BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 50429618 Fc1ccc2n(c(nc2c1)-c1ccccn1)-c1ccc(OCCCN2CCCCC2)cc1 InChI=1S/C26H27FN4O/c27-20-8-13-25-24(19-20)29-26(23-7-2-3-14-28-23)31(25)21-9-11-22(12-10-21)32-18-6-17-30-15-4-1-5-16-30/h2-3,7-14,19H,1,4-6,15-18H2 ILIWVAFIMXCJTB-UHFFFAOYSA-N 50264895 5-fluoro-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)-2-(pyridin-2-yl)-1H-benzo[d]imidazole::CHEMBL495698 Histamine H3 receptor Mus musculus 1.8 ChEMBL 10.1016/j.bmcl.2008.08.008 10.7270/Q2CZ370Q 18752952 Aslanian, R; Zhu, X; Vaccaro, HA; Shih, NY; Piwinski, JJ; Williams, SM; West, RE The Schering Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264895 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264895&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 11532065 104112737 CHEMBL495698 ZINC40972403 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50436014 Cc1nc2cccc(F)c2c(=O)n1-c1ccc(OC2CCN(CC2)C2CCC2)cc1 InChI=1S/C24H26FN3O2/c1-16-26-22-7-3-6-21(25)23(22)24(29)28(16)18-8-10-19(11-9-18)30-20-12-14-27(15-13-20)17-4-2-5-17/h3,6-11,17,20H,2,4-5,12-15H2,1H3 HOYKNPXNYUOCRM-UHFFFAOYSA-N 50274692 3-(4-[(1-Cyclobutyl-4-piperidinyl)oxy]phenyl)-5-fluoro-2-methyl-4(3H)-quinazolinone::CHEMBL483400 Histamine H3 receptor Mus musculus 8.4 ChEMBL 10.1021/jm800569w 10.7270/Q27P8Z60 18841880 Nagase, T; Mizutani, T; Sekino, E; Ishikawa, S; Ito, S; Mitobe, Y; Miyamoto, Y; Yoshimoto, R; Tanaka, T; Ishihara, A; Takenaga, N; Tokita, S; Sato, N Tsukuba Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274692 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274692&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 23151209 104118384 CHEMBL483400 ZINC40936938 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50436015 Cc1cccc2nc(C)n(-c3ccc(OC4CCN(CC4)C4CCC4)cc3)c(=O)c12 InChI=1S/C25H29N3O2/c1-17-5-3-8-23-24(17)25(29)28(18(2)26-23)20-9-11-21(12-10-20)30-22-13-15-27(16-14-22)19-6-4-7-19/h3,5,8-12,19,22H,4,6-7,13-16H2,1-2H3 LCORHUWUZKGEHY-UHFFFAOYSA-N 50274200 3-(4-[(1-Cyclobutyl-4-piperidinyl)oxy]phenyl)-2,5-dimethyl-4(3H)-quinazolinone::CHEMBL484946 Histamine H3 receptor Mus musculus 3.9 ChEMBL 10.1021/jm800569w 10.7270/Q27P8Z60 18841880 Nagase, T; Mizutani, T; Sekino, E; Ishikawa, S; Ito, S; Mitobe, Y; Miyamoto, Y; Yoshimoto, R; Tanaka, T; Ishihara, A; Takenaga, N; Tokita, S; Sato, N Tsukuba Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274200 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274200&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 23151367 104118041 CHEMBL484946 ZINC40943550 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50436016 Cc1nc2cccc(c2c(=O)n1-c1ccc(OC2CCN(CC2)C2CCC2)cc1)C(F)(F)F InChI=1S/C25H26F3N3O2/c1-16-29-22-7-3-6-21(25(26,27)28)23(22)24(32)31(16)18-8-10-19(11-9-18)33-20-12-14-30(15-13-20)17-4-2-5-17/h3,6-11,17,20H,2,4-5,12-15H2,1H3 ZWUFGBNOUKQGBR-UHFFFAOYSA-N 50274235 3-(4-[(1-Cyclobutyl-4-piperidinyl)oxy]phenyl)-2-methyl-5-(trifluoromethyl)-4(3H)-quinazolinone::CHEMBL485543 Histamine H3 receptor Mus musculus 3.9 ChEMBL 10.1021/jm800569w 10.7270/Q27P8Z60 18841880 Nagase, T; Mizutani, T; Sekino, E; Ishikawa, S; Ito, S; Mitobe, Y; Miyamoto, Y; Yoshimoto, R; Tanaka, T; Ishihara, A; Takenaga, N; Tokita, S; Sato, N Tsukuba Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274235 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274235&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 11973780 104118065 CHEMBL485543 ZINC40943626 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50510619 Cn1c(nc2ccccc2c1=O)-c1ccc(OCCCN2CCCC2)cc1 InChI=1S/C22H25N3O2/c1-24-21(23-20-8-3-2-7-19(20)22(24)26)17-9-11-18(12-10-17)27-16-6-15-25-13-4-5-14-25/h2-3,7-12H,4-6,13-16H2,1H3 PRPSMPHMELIHFQ-UHFFFAOYSA-N 50246289 3-methyl-2-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)quinazolin-4(3H)-one::CHEMBL488248::CHEMBL557214 Histamine H3 receptor Mus musculus 9.6 ChEMBL 10.1016/j.bmcl.2009.06.025 10.7270/Q2GQ6XSZ 19553110 Mitobe, Y; Ito, S; Mizutani, T; Nagase, T; Sato, N; Tokita, S Tsukuba Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50246289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50246289&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 11581337 104101752 CHEMBL557214CHEMBL488248 ZINC14211500 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50510620 NC(SCCCc1cnc[nH]1)=NCc1ccc(Cl)cc1 InChI=1S/C14H17ClN4S/c15-12-5-3-11(4-6-12)8-18-14(16)20-7-1-2-13-9-17-10-19-13/h3-6,9-10H,1-2,7-8H2,(H2,16,18)(H,17,19) UCAIEVHKDLMIFL-UHFFFAOYSA-N 22541 Clobenpropit::N''-[(4-chlorophenyl)methyl]{[3-(1H-imidazol-5-yl)propyl]sulfanyl}methanimidamide::VUF 9153::VUF-9153::VUF9153 Histamine H3 receptor Mus musculus 1.7 ChEMBL 10.1016/j.bmcl.2009.06.025 10.7270/Q2GQ6XSZ 19553110 Mitobe, Y; Ito, S; Mizutani, T; Nagase, T; Sato, N; Tokita, S Tsukuba Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22541 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22541&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 2790 49846355 1223 ZINC14951170 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50510621 S=C(NC1CCCCC1)N1CCC(CC1)c1cnc[nH]1 InChI=1S/C15H24N4S/c20-15(18-13-4-2-1-3-5-13)19-8-6-12(7-9-19)14-10-16-11-17-14/h10-13H,1-9H2,(H,16,17)(H,18,20) QKDDJDBFONZGBW-UHFFFAOYSA-N 22914 CHEMBL260374::N-cyclohexyl-4-(1H-imidazol-5-yl)piperidine-1-carbothioamide::Thioperamide::US11622967, Compound Thioperamide Histamine H3 receptor Mus musculus 11 ChEMBL 10.1016/j.bmcl.2009.06.025 10.7270/Q2GQ6XSZ 19553110 Mitobe, Y; Ito, S; Mizutani, T; Nagase, T; Sato, N; Tokita, S Tsukuba Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22914&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search FJZ 3MDM 3035905 49846728 CHEMBL260374 1267 ZINC13108134 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50510627 Cn1c(nc2ccccc2c1=O)-c1ccc(OCCCN2CCCC2)cc1 InChI=1S/C22H25N3O2/c1-24-21(23-20-8-3-2-7-19(20)22(24)26)17-9-11-18(12-10-17)27-16-6-15-25-13-4-5-14-25/h2-3,7-12H,4-6,13-16H2,1H3 PRPSMPHMELIHFQ-UHFFFAOYSA-N 50246289 3-methyl-2-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)quinazolin-4(3H)-one::CHEMBL488248::CHEMBL557214 Histamine H3 receptor Mus musculus 2.6 ChEMBL 10.1016/j.bmcl.2009.06.025 10.7270/Q2GQ6XSZ 19553110 Mitobe, Y; Ito, S; Mizutani, T; Nagase, T; Sato, N; Tokita, S Tsukuba Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50246289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50246289&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 11581337 104101752 CHEMBL557214CHEMBL488248 ZINC14211500 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50510628 Cn1c(nc2ccccc2c1=O)-c1ccc(OCCCN2CCCC2)cc1 InChI=1S/C22H25N3O2/c1-24-21(23-20-8-3-2-7-19(20)22(24)26)17-9-11-18(12-10-17)27-16-6-15-25-13-4-5-14-25/h2-3,7-12H,4-6,13-16H2,1H3 PRPSMPHMELIHFQ-UHFFFAOYSA-N 50246289 3-methyl-2-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)quinazolin-4(3H)-one::CHEMBL488248::CHEMBL557214 Histamine H3 receptor Mus musculus 2.4 ChEMBL 10.1016/j.bmcl.2009.06.025 10.7270/Q2GQ6XSZ 19553110 Mitobe, Y; Ito, S; Mizutani, T; Nagase, T; Sato, N; Tokita, S Tsukuba Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50246289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50246289&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 11581337 104101752 CHEMBL557214CHEMBL488248 ZINC14211500 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50510629 NC(=N)SCCc1cnc[nH]1 InChI=1S/C6H10N4S/c7-6(8)11-2-1-5-3-9-4-10-5/h3-4H,1-2H2,(H3,7,8)(H,9,10) PEHSVUKQDJULKE-UHFFFAOYSA-N 22911 2-(3H-imidazol-4-yl)ethylsulfanylmethanimidamide::CHEMBL19439::CHEMBL544911::Imetit::{[2-(1H-imidazol-4-yl)ethyl]sulfanyl}methanimidamide Histamine H3 receptor Mus musculus 2 ChEMBL 10.1016/j.bmcl.2009.06.025 10.7270/Q2GQ6XSZ 19553110 Mitobe, Y; Ito, S; Mizutani, T; Nagase, T; Sato, N; Tokita, S Tsukuba Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22911 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22911&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 3692 49846725 64156 CHEMBL544911CHEMBL19439 1250 ZINC05425255 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50510630 NCCc1cnc[nH]1 InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8) NTYJJOPFIAHURM-UHFFFAOYSA-N 7966 2-(1H-imidazol-4-yl)ethan-1-amine::CHEMBL544208::CHEMBL90::Ceplene::Ergotidine::HISTAMINE DIHYDROCHLORIDE::Histamine::L-histamine::Peremin::[3H]histamine Histamine H3 receptor Mus musculus 68 ChEMBL 10.1016/j.bmcl.2009.06.025 10.7270/Q2GQ6XSZ 19553110 Mitobe, Y; Ito, S; Mizutani, T; Nagase, T; Sato, N; Tokita, S Tsukuba Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=7966 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=7966&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 1AVN,1IKE,1JQD,1KAR,1NP1,1QFT,1QFV,1U18 774 11108702 18295 CHEMBL90CHEMBL544208 DB00667 1247 ZINC18217584 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50510631 CNCCc1cnc[nH]1 InChI=1S/C6H11N3/c1-7-3-2-6-4-8-5-9-6/h4-5,7H,2-3H2,1H3,(H,8,9) PHSPJQZRQAJPPF-UHFFFAOYSA-N 22530 N(alpha)-Methylhistamine::N-alpha-methylhistamine::N-methylhistamine::NAMH::[2-(1H-imidazol-5-yl)ethyl](methyl)amine::[3H]N-alpha-methyl histamine Histamine H3 receptor Mus musculus 19 ChEMBL 10.1016/j.bmcl.2009.06.025 10.7270/Q2GQ6XSZ 19553110 Mitobe, Y; Ito, S; Mizutani, T; Nagase, T; Sato, N; Tokita, S Tsukuba Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22530 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22530&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 912 49846344 1240 ZINC02559937 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50510632 NC(SCCCc1cnc[nH]1)=NCc1ccc(Cl)cc1 InChI=1S/C14H17ClN4S/c15-12-5-3-11(4-6-12)8-18-14(16)20-7-1-2-13-9-17-10-19-13/h3-6,9-10H,1-2,7-8H2,(H2,16,18)(H,17,19) UCAIEVHKDLMIFL-UHFFFAOYSA-N 22541 Clobenpropit::N''-[(4-chlorophenyl)methyl]{[3-(1H-imidazol-5-yl)propyl]sulfanyl}methanimidamide::VUF 9153::VUF-9153::VUF9153 Histamine H3 receptor Mus musculus 0.6 ChEMBL 10.1016/j.bmcl.2009.06.025 10.7270/Q2GQ6XSZ 19553110 Mitobe, Y; Ito, S; Mizutani, T; Nagase, T; Sato, N; Tokita, S Tsukuba Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22541 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22541&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 2790 49846355 1223 ZINC14951170 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50510633 S=C(NC1CCCCC1)N1CCC(CC1)c1cnc[nH]1 InChI=1S/C15H24N4S/c20-15(18-13-4-2-1-3-5-13)19-8-6-12(7-9-19)14-10-16-11-17-14/h10-13H,1-9H2,(H,16,17)(H,18,20) QKDDJDBFONZGBW-UHFFFAOYSA-N 22914 CHEMBL260374::N-cyclohexyl-4-(1H-imidazol-5-yl)piperidine-1-carbothioamide::Thioperamide::US11622967, Compound Thioperamide Histamine H3 receptor Mus musculus 4.8 ChEMBL 10.1016/j.bmcl.2009.06.025 10.7270/Q2GQ6XSZ 19553110 Mitobe, Y; Ito, S; Mizutani, T; Nagase, T; Sato, N; Tokita, S Tsukuba Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22914&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search FJZ 3MDM 3035905 49846728 CHEMBL260374 1267 ZINC13108134 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50510634 Cn1c(nc2ccccc2c1=O)-c1ccc(OCCCN2CCCC2)cc1 InChI=1S/C22H25N3O2/c1-24-21(23-20-8-3-2-7-19(20)22(24)26)17-9-11-18(12-10-17)27-16-6-15-25-13-4-5-14-25/h2-3,7-12H,4-6,13-16H2,1H3 PRPSMPHMELIHFQ-UHFFFAOYSA-N 50246289 3-methyl-2-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)quinazolin-4(3H)-one::CHEMBL488248::CHEMBL557214 Histamine H3 receptor Mus musculus 3.1 ChEMBL 10.1016/j.bmcl.2009.06.025 10.7270/Q2GQ6XSZ 19553110 Mitobe, Y; Ito, S; Mizutani, T; Nagase, T; Sato, N; Tokita, S Tsukuba Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50246289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50246289&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 11581337 104101752 CHEMBL557214CHEMBL488248 ZINC14211500 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50513015 COc1cccc2c1O[C@H]([C@H](C)S2(=O)=O)c1ccc(OCCCN2CCCC2)cc1 InChI=1S/C23H29NO5S/c1-17-22(29-23-20(27-2)7-5-8-21(23)30(17,25)26)18-9-11-19(12-10-18)28-16-6-15-24-13-3-4-14-24/h5,7-12,17,22H,3-4,6,13-16H2,1-2H3/t17-,22+/m0/s1 CHCVZZOPCAVWNV-HTAPYJJXSA-N 50296171 1-{3-[4-((2S,3S)-8-Methoxy-3-methyl-4,4-dioxo-3,4-dihydro-2H-4lambda*6*-benzo[1,4]oxathiin-2-yl)-phenoxy]-propyl}-pyrrolidine::CHEMBL560386 Histamine H3 receptor Mus musculus 5.9 ChEMBL 10.1016/j.bmcl.2009.05.101 10.7270/Q20G3K69 19520574 Sasaki, T; Takahashi, T; Nagase, T; Mizutani, T; Ito, S; Mitobe, Y; Miyamoto, Y; Kanesaka, M; Yoshimoto, R; Tanaka, T; Takenaga, N; Tokita, S; Sato, N Tsukuba Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50296171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50296171&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 44250288 104137702 CHEMBL560386 ZINC43009044 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50531765 Clc1cc2sc(nc2cn1)N1CCC(CC1)N1CCCCC1 InChI=1S/C16H21ClN4S/c17-15-10-14-13(11-18-15)19-16(22-14)21-8-4-12(5-9-21)20-6-2-1-3-7-20/h10-12H,1-9H2 QUGZEKVHJOWGND-UHFFFAOYSA-N 50299014 2-(1,4'-bipiperidin-1'-yl)-6-chlorothiazolo[4,5-c]pyridine::CHEMBL575474 Histamine H3 receptor Mus musculus 75 ChEMBL 10.1016/j.bmcl.2009.09.006 10.7270/Q2NC618K 19773164 Rao, AU; Palani, A; Chen, X; Huang, Y; Aslanian, RG; West, RE; Williams, SM; Wu, RL; Hwa, J; Sondey, C; Lachowicz, J Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50299014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50299014&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 45482684 104140543 CHEMBL575474 ZINC45291197 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50531766 Nc1ccc(cn1)-c1cnc2nc(sc2c1)N1CCC(CC1)N1CCCCC1 InChI=1S/C21H26N6S/c22-19-5-4-15(13-23-19)16-12-18-20(24-14-16)25-21(28-18)27-10-6-17(7-11-27)26-8-2-1-3-9-26/h4-5,12-14,17H,1-3,6-11H2,(H2,22,23) LKQAEEFKVPULTI-UHFFFAOYSA-N 50299034 5-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-b]pyridin-6-yl)pyridin-2-amine::CHEMBL575241 Histamine H3 receptor Mus musculus 32 ChEMBL 10.1016/j.bmcl.2009.09.006 10.7270/Q2NC618K 19773164 Rao, AU; Palani, A; Chen, X; Huang, Y; Aslanian, RG; West, RE; Williams, SM; Wu, RL; Hwa, J; Sondey, C; Lachowicz, J Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50299034 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50299034&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 45482705 104140563 CHEMBL575241 ZINC45289423 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50531767 CC(=O)Nc1ccc(cn1)-c1cnc2nc(sc2c1)N1CCC(CC1)N1CCCCC1 InChI=1S/C23H28N6OS/c1-16(30)26-21-6-5-17(14-24-21)18-13-20-22(25-15-18)27-23(31-20)29-11-7-19(8-12-29)28-9-3-2-4-10-28/h5-6,13-15,19H,2-4,7-12H2,1H3,(H,24,26,30) IOCHHPRTMWARFO-UHFFFAOYSA-N 50299035 CHEMBL574387::N-(5-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-b]pyridin-6-yl)pyridin-2-yl)acetamide Histamine H3 receptor Mus musculus 20 ChEMBL 10.1016/j.bmcl.2009.09.006 10.7270/Q2NC618K 19773164 Rao, AU; Palani, A; Chen, X; Huang, Y; Aslanian, RG; West, RE; Williams, SM; Wu, RL; Hwa, J; Sondey, C; Lachowicz, J Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50299035 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50299035&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 45482727 104140564 CHEMBL574387 ZINC45287498 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50531768 C1CCN(CC1)C1CCN(CC1)c1nc2ncc(cc2s1)-c1cncnc1 InChI=1S/C20H24N6S/c1-2-6-25(7-3-1)17-4-8-26(9-5-17)20-24-19-18(27-20)10-15(13-23-19)16-11-21-14-22-12-16/h10-14,17H,1-9H2 WVXYZXRHQOUJJQ-UHFFFAOYSA-N 50299036 2-(1,4'-bipiperidin-1'-yl)-6-(pyrimidin-5-yl)thiazolo[4,5-b]pyridine::CHEMBL575476 Histamine H3 receptor Mus musculus 66 ChEMBL 10.1016/j.bmcl.2009.09.006 10.7270/Q2NC618K 19773164 Rao, AU; Palani, A; Chen, X; Huang, Y; Aslanian, RG; West, RE; Williams, SM; Wu, RL; Hwa, J; Sondey, C; Lachowicz, J Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50299036 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50299036&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 45482745 104140565 CHEMBL575476 ZINC45291203 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50531769 Fc1ccc(cn1)-c1cc2sc(nc2cn1)N1CCC(CC1)N1CCCCC1 InChI=1S/C21H24FN5S/c22-20-5-4-15(13-24-20)17-12-19-18(14-23-17)25-21(28-19)27-10-6-16(7-11-27)26-8-2-1-3-9-26/h4-5,12-14,16H,1-3,6-11H2 QINCTGKEJQBZLN-UHFFFAOYSA-N 50299038 2-(1,4'-bipiperidin-1'-yl)-6-(6-fluoropyridin-3-yl)thiazolo[4,5-c]pyridine::CHEMBL575023 Histamine H3 receptor Mus musculus 89 ChEMBL 10.1016/j.bmcl.2009.09.006 10.7270/Q2NC618K 19773164 Rao, AU; Palani, A; Chen, X; Huang, Y; Aslanian, RG; West, RE; Williams, SM; Wu, RL; Hwa, J; Sondey, C; Lachowicz, J Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50299038 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50299038&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 45482756 104140567 CHEMBL575023 ZINC45301018 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50531770 O=c1ccc(c[nH]1)-c1cc2sc(nc2cn1)N1CCC(CC1)N1CCCCC1 InChI=1S/C21H25N5OS/c27-20-5-4-15(13-23-20)17-12-19-18(14-22-17)24-21(28-19)26-10-6-16(7-11-26)25-8-2-1-3-9-25/h4-5,12-14,16H,1-3,6-11H2,(H,23,27) VQVGSCXKGOBRQK-UHFFFAOYSA-N 50299045 5-(2-(1,4'-bipiperidin-1'-yl)thiazolo[4,5-c]pyridin-6-yl)pyridin-2-ol::CHEMBL578834 Histamine H3 receptor Mus musculus 20 ChEMBL 10.1016/j.bmcl.2009.09.006 10.7270/Q2NC618K 19773164 Rao, AU; Palani, A; Chen, X; Huang, Y; Aslanian, RG; West, RE; Williams, SM; Wu, RL; Hwa, J; Sondey, C; Lachowicz, J Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50299045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50299045&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 45482728 104140574 CHEMBL578834 ZINC45302983 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50604068 NC(SCCCc1cnc[nH]1)=NCc1ccc(Cl)cc1 InChI=1S/C14H17ClN4S/c15-12-5-3-11(4-6-12)8-18-14(16)20-7-1-2-13-9-17-10-19-13/h3-6,9-10H,1-2,7-8H2,(H2,16,18)(H,17,19) UCAIEVHKDLMIFL-UHFFFAOYSA-N 22541 Clobenpropit::N''-[(4-chlorophenyl)methyl]{[3-(1H-imidazol-5-yl)propyl]sulfanyl}methanimidamide::VUF 9153::VUF-9153::VUF9153 Histamine H3 receptor Mus musculus 1 ChEMBL 10.1016/j.bmcl.2010.08.099 10.7270/Q2DF6RGG 20833043 Anderson, JT; Campbell, M; Wang, J; Brunden, KR; Harrington, JJ; Stricker-Krongrad, A; Song, J; Doucette, C; Murphy, S; Bennani, YL Athersys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22541 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22541&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 2790 49846355 1223 ZINC14951170 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50604069 CC1CC(O)(C#Cc2cccc3ccccc23)C(C)CN1C InChI=1S/C20H23NO/c1-15-14-21(3)16(2)13-20(15,22)12-11-18-9-6-8-17-7-4-5-10-19(17)18/h4-10,15-16,22H,13-14H2,1-3H3 UATGXLFLKRXZBK-UHFFFAOYSA-N 50328801 1,2,5-trimethyl-4-(naphthalen-1-ylethynyl)piperidin-4-ol::CHEMBL1269843 Histamine H3 receptor Mus musculus 280 ChEMBL 10.1016/j.bmcl.2010.08.099 10.7270/Q2DF6RGG 20833043 Anderson, JT; Campbell, M; Wang, J; Brunden, KR; Harrington, JJ; Stricker-Krongrad, A; Song, J; Doucette, C; Murphy, S; Bennani, YL Athersys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50328801 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50328801&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 550705 123107916 CHEMBL1269843 ZINC05276268 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50604070 C[C@@H]1C[C@@](O)(C#Cc2cccc3ccccc23)[C@@H](C)CN1C InChI=1S/C20H23NO/c1-15-14-21(3)16(2)13-20(15,22)12-11-18-9-6-8-17-7-4-5-10-19(17)18/h4-10,15-16,22H,13-14H2,1-3H3/t15-,16+,20-/m0/s1 UATGXLFLKRXZBK-YRNRMSPPSA-N 50328802 (2R,4S,5S)-1,2,5-trimethyl-4-(naphthalen-1-ylethynyl)piperidin-4-ol::CHEMBL1269844 Histamine H3 receptor Mus musculus 119 ChEMBL 10.1016/j.bmcl.2010.08.099 10.7270/Q2DF6RGG 20833043 Anderson, JT; Campbell, M; Wang, J; Brunden, KR; Harrington, JJ; Stricker-Krongrad, A; Song, J; Doucette, C; Murphy, S; Bennani, YL Athersys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50328802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50328802&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 52941057 123107917 CHEMBL1269844 ZINC32218062 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50604071 C[C@H]1C[C@](O)(C#Cc2cccc3ccccc23)[C@H](C)CN1C InChI=1S/C20H23NO/c1-15-14-21(3)16(2)13-20(15,22)12-11-18-9-6-8-17-7-4-5-10-19(17)18/h4-10,15-16,22H,13-14H2,1-3H3/t15-,16+,20-/m1/s1 UATGXLFLKRXZBK-GQIGUUNPSA-N 50328803 (2S,4R,5R)-1,2,5-trimethyl-4-(naphthalen-1-ylethynyl)piperidin-4-ol::CHEMBL1269950 Histamine H3 receptor Mus musculus 1318 ChEMBL 10.1016/j.bmcl.2010.08.099 10.7270/Q2DF6RGG 20833043 Anderson, JT; Campbell, M; Wang, J; Brunden, KR; Harrington, JJ; Stricker-Krongrad, A; Song, J; Doucette, C; Murphy, S; Bennani, YL Athersys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50328803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50328803&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 52941061 123107918 CHEMBL1269950 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50604072 CC1CC(OC(C)=O)(C#Cc2cccc3ccccc23)C(C)CN1C InChI=1S/C22H25NO2/c1-16-15-23(4)17(2)14-22(16,25-18(3)24)13-12-20-10-7-9-19-8-5-6-11-21(19)20/h5-11,16-17H,14-15H2,1-4H3 RENBHJFCFJUFID-UHFFFAOYSA-N 50328804 CHEMBL1269951::rac-1,2,5-trimethyl-4-(naphthalen-1-ylethynyl)piperidin-4-yl acetate Histamine H3 receptor Mus musculus >10000 ChEMBL 10.1016/j.bmcl.2010.08.099 10.7270/Q2DF6RGG 20833043 Anderson, JT; Campbell, M; Wang, J; Brunden, KR; Harrington, JJ; Stricker-Krongrad, A; Song, J; Doucette, C; Murphy, S; Bennani, YL Athersys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50328804 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50328804&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 52941062 123107919 CHEMBL1269951 ZINC64512626 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50604073 CC1CC(O)(\C=C\c2cccc3ccccc23)C(C)CN1C InChI=1S/C20H25NO/c1-15-14-21(3)16(2)13-20(15,22)12-11-18-9-6-8-17-7-4-5-10-19(17)18/h4-12,15-16,22H,13-14H2,1-3H3/b12-11+ SFCXMYLLNIDIPQ-VAWYXSNFSA-N 50328805 CHEMBL1269952::rac-1,2,5-trimethyl-4-(2-(naphthalen-1-yl)vinyl)piperidin-4-ol Histamine H3 receptor Mus musculus 570 ChEMBL 10.1016/j.bmcl.2010.08.099 10.7270/Q2DF6RGG 20833043 Anderson, JT; Campbell, M; Wang, J; Brunden, KR; Harrington, JJ; Stricker-Krongrad, A; Song, J; Doucette, C; Murphy, S; Bennani, YL Athersys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50328805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50328805&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 52944686 123107920 CHEMBL1269952 ZINC64512632 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50604074 CC1CC(O)(CCc2cccc3ccccc23)C(C)CN1C InChI=1S/C20H27NO/c1-15-14-21(3)16(2)13-20(15,22)12-11-18-9-6-8-17-7-4-5-10-19(17)18/h4-10,15-16,22H,11-14H2,1-3H3 JYWKRWWPTYARAS-UHFFFAOYSA-N 50328806 CHEMBL1270058::rac-1,2,5-trimethyl-4-(2-(naphthalen-1-yl)ethyl)piperidin-4-ol Histamine H3 receptor Mus musculus 480 ChEMBL 10.1016/j.bmcl.2010.08.099 10.7270/Q2DF6RGG 20833043 Anderson, JT; Campbell, M; Wang, J; Brunden, KR; Harrington, JJ; Stricker-Krongrad, A; Song, J; Doucette, C; Murphy, S; Bennani, YL Athersys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50328806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50328806&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 52943448 123107921 CHEMBL1270058 ZINC64526847 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50604075 C[C@@H]1C[C@@](O)(CCc2cccc3ccccc23)[C@@H](C)CN1C InChI=1S/C20H27NO/c1-15-14-21(3)16(2)13-20(15,22)12-11-18-9-6-8-17-7-4-5-10-19(17)18/h4-10,15-16,22H,11-14H2,1-3H3/t15-,16+,20-/m0/s1 JYWKRWWPTYARAS-YRNRMSPPSA-N 50328807 (2R,4S,5S)-1,2,5-trimethyl-4-(2-(naphthalen-1-yl)ethyl)piperidin-4-ol::CHEMBL1270059 Histamine H3 receptor Mus musculus 85 ChEMBL 10.1016/j.bmcl.2010.08.099 10.7270/Q2DF6RGG 20833043 Anderson, JT; Campbell, M; Wang, J; Brunden, KR; Harrington, JJ; Stricker-Krongrad, A; Song, J; Doucette, C; Murphy, S; Bennani, YL Athersys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50328807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50328807&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 52941024 123107922 CHEMBL1270059 ZINC43131272 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50604076 CC1CC(O)(C#Cc2ccc3ccccc3c2)C(C)CN1C InChI=1S/C20H23NO/c1-15-14-21(3)16(2)13-20(15,22)11-10-17-8-9-18-6-4-5-7-19(18)12-17/h4-9,12,15-16,22H,13-14H2,1-3H3 NBAJUKAFIJTFNK-UHFFFAOYSA-N 50328808 CHEMBL1270060::rac-1,2,5-trimethyl-4-(naphthalen-2-ylethynyl)piperidin-4-ol Histamine H3 receptor Mus musculus 810 ChEMBL 10.1016/j.bmcl.2010.08.099 10.7270/Q2DF6RGG 20833043 Anderson, JT; Campbell, M; Wang, J; Brunden, KR; Harrington, JJ; Stricker-Krongrad, A; Song, J; Doucette, C; Murphy, S; Bennani, YL Athersys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50328808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50328808&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 52943449 123107923 CHEMBL1270060 ZINC64539095 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50604077 CC1CC(O)(CCc2ccc3ccccc3c2)C(C)CN1C InChI=1S/C20H27NO/c1-15-14-21(3)16(2)13-20(15,22)11-10-17-8-9-18-6-4-5-7-19(18)12-17/h4-9,12,15-16,22H,10-11,13-14H2,1-3H3 ICKWJAMESDNKEK-UHFFFAOYSA-N 50328809 CHEMBL1270165::rac-1,2,5-trimethyl-4-(2-(naphthalen-2-yl)ethyl)piperidin-4-ol Histamine H3 receptor Mus musculus 122 ChEMBL 10.1016/j.bmcl.2010.08.099 10.7270/Q2DF6RGG 20833043 Anderson, JT; Campbell, M; Wang, J; Brunden, KR; Harrington, JJ; Stricker-Krongrad, A; Song, J; Doucette, C; Murphy, S; Bennani, YL Athersys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50328809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50328809&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 52942843 123107924 CHEMBL1270165 ZINC64539334 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50604078 CC1CN2CCCC2CC1(O)C#Cc1cccc2ccccc12 InChI=1S/C21H23NO/c1-16-15-22-13-5-9-19(22)14-21(16,23)12-11-18-8-4-7-17-6-2-3-10-20(17)18/h2-4,6-8,10,16,19,23H,5,9,13-15H2,1H3 KJULEEZSUWCDAJ-UHFFFAOYSA-N 50328810 CHEMBL1270166::rac-6-methyl-7-(naphthalen-1-ylethynyl)octahydroindolizin-7-ol Histamine H3 receptor Mus musculus 280 ChEMBL 10.1016/j.bmcl.2010.08.099 10.7270/Q2DF6RGG 20833043 Anderson, JT; Campbell, M; Wang, J; Brunden, KR; Harrington, JJ; Stricker-Krongrad, A; Song, J; Doucette, C; Murphy, S; Bennani, YL Athersys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50328810 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50328810&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 11507778 123107925 CHEMBL1270166 ZINC64539335 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50604079 CC1CN2CCCC2CC1(O)CCc1cccc2ccccc12 InChI=1S/C21H27NO/c1-16-15-22-13-5-9-19(22)14-21(16,23)12-11-18-8-4-7-17-6-2-3-10-20(17)18/h2-4,6-8,10,16,19,23H,5,9,11-15H2,1H3 HAVRDOLEAZFMQM-UHFFFAOYSA-N 50328811 CHEMBL1270167::rac-6-methyl-7-(2-(naphthalen-1-yl)ethyl)octahydroindolizin-7-ol Histamine H3 receptor Mus musculus 345 ChEMBL 10.1016/j.bmcl.2010.08.099 10.7270/Q2DF6RGG 20833043 Anderson, JT; Campbell, M; Wang, J; Brunden, KR; Harrington, JJ; Stricker-Krongrad, A; Song, J; Doucette, C; Murphy, S; Bennani, YL Athersys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50328811 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50328811&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 52945858 123107926 CHEMBL1270167 ZINC64539337 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50604080 CC1CC(O)(C#Cc2cccc3ncccc23)C(C)CN1C InChI=1S/C19H22N2O/c1-14-13-21(3)15(2)12-19(14,22)10-9-16-6-4-8-18-17(16)7-5-11-20-18/h4-8,11,14-15,22H,12-13H2,1-3H3 DZBYCVNSQVIDBS-UHFFFAOYSA-N 50328812 CHEMBL1270264::rac-1,2,5-trimethyl-4-(quinolin-5-ylethynyl)piperidin-4-ol Histamine H3 receptor Mus musculus 690 ChEMBL 10.1016/j.bmcl.2010.08.099 10.7270/Q2DF6RGG 20833043 Anderson, JT; Campbell, M; Wang, J; Brunden, KR; Harrington, JJ; Stricker-Krongrad, A; Song, J; Doucette, C; Murphy, S; Bennani, YL Athersys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50328812 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50328812&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 52944521 123107927 CHEMBL1270264 ZINC64526392 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50604081 CC1CC(O)(C#Cc2cccc3cccnc23)C(C)CN1C InChI=1S/C19H22N2O/c1-14-13-21(3)15(2)12-19(14,22)10-9-17-7-4-6-16-8-5-11-20-18(16)17/h4-8,11,14-15,22H,12-13H2,1-3H3 KOCLLQZLNFFUQH-UHFFFAOYSA-N 50328813 CHEMBL1270265::rac-1,2,5-trimethyl-4-(quinolin-8-ylethynyl)piperidin-4-ol Histamine H3 receptor Mus musculus 9730 ChEMBL 10.1016/j.bmcl.2010.08.099 10.7270/Q2DF6RGG 20833043 Anderson, JT; Campbell, M; Wang, J; Brunden, KR; Harrington, JJ; Stricker-Krongrad, A; Song, J; Doucette, C; Murphy, S; Bennani, YL Athersys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50328813 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50328813&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 52943330 123107928 CHEMBL1270265 ZINC64528475 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50657891 CN(C)[C@H]1CC[C@H](CC1)c1ccc(OCCCN2CCCCC2)cc1 InChI=1S/C22H36N2O/c1-23(2)21-11-7-19(8-12-21)20-9-13-22(14-10-20)25-18-6-17-24-15-4-3-5-16-24/h9-10,13-14,19,21H,3-8,11-12,15-18H2,1-2H3/t19-,21+ NBCFVKKQKAXINS-TYKWCNGQSA-N 50352081 CHEMBL1824230 Histamine H3 receptor Mus musculus 0.28 ChEMBL 10.1016/j.bmcl.2011.06.102 10.7270/Q2DV1K7H 21783360 Labeeuw, O; Levoin, N; Poupardin-Olivier, O; Calmels, T; Ligneau, X; Berrebi-Bertrand, I; Robert, P; Lecomte, JM; Schwartz, JC; Capet, M Bioprojet-Biotech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50352081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50352081&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 11978858 136358767 CHEMBL1824230 ZINC43133385 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50657929 C(COc1ccc(cc1)[C@H]1CC[C@@H](CC1)NCc1ccccc1)CN1CCCCC1 InChI=1S/C27H38N2O/c1-3-8-23(9-4-1)22-28-26-14-10-24(11-15-26)25-12-16-27(17-13-25)30-21-7-20-29-18-5-2-6-19-29/h1,3-4,8-9,12-13,16-17,24,26,28H,2,5-7,10-11,14-15,18-22H2/t24-,26- MYSZKGRXICYNIZ-YOCNBXQISA-N 50352084 CHEMBL1824247 Histamine H3 receptor Mus musculus 2.1 ChEMBL 10.1016/j.bmcl.2011.06.102 10.7270/Q2DV1K7H 21783360 Labeeuw, O; Levoin, N; Poupardin-Olivier, O; Calmels, T; Ligneau, X; Berrebi-Bertrand, I; Robert, P; Lecomte, JM; Schwartz, JC; Capet, M Bioprojet-Biotech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50352084 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50352084&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 56668953 136358770 CHEMBL1824247 ZINC72180953 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50657930 C(COc1ccc(cc1)[C@H]1CC[C@@H](CC1)N1Cc2ccccc2C1)CN1CCCCC1 InChI=1S/C28H38N2O/c1-4-17-29(18-5-1)19-6-20-31-28-15-11-24(12-16-28)23-9-13-27(14-10-23)30-21-25-7-2-3-8-26(25)22-30/h2-3,7-8,11-12,15-16,23,27H,1,4-6,9-10,13-14,17-22H2/t23-,27- IEPREURIPCPAKP-JIBACQESSA-N 50352086 CHEMBL1824245 Histamine H3 receptor Mus musculus 1.4 ChEMBL 10.1016/j.bmcl.2011.06.102 10.7270/Q2DV1K7H 21783360 Labeeuw, O; Levoin, N; Poupardin-Olivier, O; Calmels, T; Ligneau, X; Berrebi-Bertrand, I; Robert, P; Lecomte, JM; Schwartz, JC; Capet, M Bioprojet-Biotech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50352086 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50352086&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 56675823 136358772 CHEMBL1824245 ZINC72180820 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50657931 C(COc1ccc(cc1)[C@H]1CC[C@@H](CC1)N1CCOCC1)CN1CCCCC1 InChI=1S/C24H38N2O2/c1-2-13-25(14-3-1)15-4-18-28-24-11-7-22(8-12-24)21-5-9-23(10-6-21)26-16-19-27-20-17-26/h7-8,11-12,21,23H,1-6,9-10,13-20H2/t21-,23- NFMCJKWXWBIFGH-AFARHQOCSA-N 50352090 CHEMBL1824241 Histamine H3 receptor Mus musculus 1.6 ChEMBL 10.1016/j.bmcl.2011.06.102 10.7270/Q2DV1K7H 21783360 Labeeuw, O; Levoin, N; Poupardin-Olivier, O; Calmels, T; Ligneau, X; Berrebi-Bertrand, I; Robert, P; Lecomte, JM; Schwartz, JC; Capet, M Bioprojet-Biotech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50352090 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50352090&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 11977494 136358776 CHEMBL1824241 ZINC34774969 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50657932 CN1CCN(CC1)[C@H]1CC[C@@H](CC1)c1ccc(OCCCN2CCCCC2)cc1 InChI=1S/C25H41N3O/c1-26-17-19-28(20-18-26)24-10-6-22(7-11-24)23-8-12-25(13-9-23)29-21-5-16-27-14-3-2-4-15-27/h8-9,12-13,22,24H,2-7,10-11,14-21H2,1H3/t22-,24- CAGJHEKGANXSNK-HCGLCNNCSA-N 50352092 CHEMBL1824239 Histamine H3 receptor Mus musculus 2.3 ChEMBL 10.1016/j.bmcl.2011.06.102 10.7270/Q2DV1K7H 21783360 Labeeuw, O; Levoin, N; Poupardin-Olivier, O; Calmels, T; Ligneau, X; Berrebi-Bertrand, I; Robert, P; Lecomte, JM; Schwartz, JC; Capet, M Bioprojet-Biotech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50352092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50352092&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 56658588 136358778 CHEMBL1824239 ZINC72182606 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50657933 C(COc1ccc(cc1)[C@H]1CC[C@@H](CC1)N1CCCCC1)CN1CCCCC1 InChI=1S/C25H40N2O/c1-3-16-26(17-4-1)18-7-21-28-25-14-10-23(11-15-25)22-8-12-24(13-9-22)27-19-5-2-6-20-27/h10-11,14-15,22,24H,1-9,12-13,16-21H2/t22-,24- DQDIOQCBDIFEQD-HCGLCNNCSA-N 50352101 CHEMBL1824236 Histamine H3 receptor Mus musculus 1 ChEMBL 10.1016/j.bmcl.2011.06.102 10.7270/Q2DV1K7H 21783360 Labeeuw, O; Levoin, N; Poupardin-Olivier, O; Calmels, T; Ligneau, X; Berrebi-Bertrand, I; Robert, P; Lecomte, JM; Schwartz, JC; Capet, M Bioprojet-Biotech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50352101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50352101&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 56662041 136358787 CHEMBL1824236 ZINC72180688 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50657934 C(COc1ccc(cc1)[C@H]1CC[C@@H](CC1)N1CCCC1)CN1CCCCC1 InChI=1S/C24H38N2O/c1-2-15-25(16-3-1)17-6-20-27-24-13-9-22(10-14-24)21-7-11-23(12-8-21)26-18-4-5-19-26/h9-10,13-14,21,23H,1-8,11-12,15-20H2/t21-,23- IIGOTHGDDVVXRO-AFARHQOCSA-N 50352095 CHEMBL1824235 Histamine H3 receptor Mus musculus 0.33 ChEMBL 10.1016/j.bmcl.2011.06.102 10.7270/Q2DV1K7H 21783360 Labeeuw, O; Levoin, N; Poupardin-Olivier, O; Calmels, T; Ligneau, X; Berrebi-Bertrand, I; Robert, P; Lecomte, JM; Schwartz, JC; Capet, M Bioprojet-Biotech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50352095 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50352095&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 11978859 136358781 CHEMBL1824235 ZINC72180687 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50657935 C(COc1ccc(cc1)[C@@H]1CC[C@@H](CC1)N1CCCC1)CN1CCCCC1 InChI=1S/C24H38N2O/c1-2-15-25(16-3-1)17-6-20-27-24-13-9-22(10-14-24)21-7-11-23(12-8-21)26-18-4-5-19-26/h9-10,13-14,21,23H,1-8,11-12,15-20H2/t21-,23+ IIGOTHGDDVVXRO-DKXQDJALSA-N 50352096 CHEMBL1824234 Histamine H3 receptor Mus musculus 1 ChEMBL 10.1016/j.bmcl.2011.06.102 10.7270/Q2DV1K7H 21783360 Labeeuw, O; Levoin, N; Poupardin-Olivier, O; Calmels, T; Ligneau, X; Berrebi-Bertrand, I; Robert, P; Lecomte, JM; Schwartz, JC; Capet, M Bioprojet-Biotech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50352096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50352096&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 11978859 136358782 CHEMBL1824234 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50657936 C(COc1ccc(cc1)[C@H]1CC[C@@H](CC1)N1CCC1)CN1CCCCC1 InChI=1S/C23H36N2O/c1-2-14-24(15-3-1)16-5-19-26-23-12-8-21(9-13-23)20-6-10-22(11-7-20)25-17-4-18-25/h8-9,12-13,20,22H,1-7,10-11,14-19H2/t20-,22- BUPDKQVYUKWVSM-AQYVVDRMSA-N 50352097 CHEMBL1824233 Histamine H3 receptor Mus musculus 1.6 ChEMBL 10.1016/j.bmcl.2011.06.102 10.7270/Q2DV1K7H 21783360 Labeeuw, O; Levoin, N; Poupardin-Olivier, O; Calmels, T; Ligneau, X; Berrebi-Bertrand, I; Robert, P; Lecomte, JM; Schwartz, JC; Capet, M Bioprojet-Biotech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50352097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50352097&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 56662040 136358783 CHEMBL1824233 ZINC72182069 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50657937 CN(C)[C@H]1CC[C@@H](CC1)c1ccc(OCCCN2CCCCC2)cc1 InChI=1S/C22H36N2O/c1-23(2)21-11-7-19(8-12-21)20-9-13-22(14-10-20)25-18-6-17-24-15-4-3-5-16-24/h9-10,13-14,19,21H,3-8,11-12,15-18H2,1-2H3/t19-,21- NBCFVKKQKAXINS-XUTJKUGGSA-N 50352099 CHEMBL1824231 Histamine H3 receptor Mus musculus 0.52 ChEMBL 10.1016/j.bmcl.2011.06.102 10.7270/Q2DV1K7H 21783360 Labeeuw, O; Levoin, N; Poupardin-Olivier, O; Calmels, T; Ligneau, X; Berrebi-Bertrand, I; Robert, P; Lecomte, JM; Schwartz, JC; Capet, M Bioprojet-Biotech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50352099 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50352099&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 11978858 136358785 CHEMBL1824231 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50710369 Nc1nc(N2CCNCC2)c2ccc(cc2n1)-c1ccco1 InChI=1S/C16H17N5O/c17-16-19-13-10-11(14-2-1-9-22-14)3-4-12(13)15(20-16)21-7-5-18-6-8-21/h1-4,9-10,18H,5-8H2,(H2,17,19,20) UBEJREHBDACTGD-UHFFFAOYSA-N 50361012 CHEMBL1935574 Histamine H3 receptor Mus musculus 1070 ChEMBL 10.1016/j.bmcl.2011.10.104 10.7270/Q2D79BT2 22153663 Smits, RA; Lim, HD; van der Meer, T; Kuhne, S; Bessembinder, K; Zuiderveld, OP; Wijtmans, M; de Esch, IJ; Leurs, R Griffin Discoveries BV http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50361012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50361012&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 56835171 136965074 CHEMBL1935574 ZINC73223166 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50934653 Cc1nnc(o1)-c1cccc(c1)-c1nnc(s1)N1CCC(CC1)N1CCCCC1 InChI=1S/C21H26N6OS/c1-15-22-23-19(28-15)16-6-5-7-17(14-16)20-24-25-21(29-20)27-12-8-18(9-13-27)26-10-3-2-4-11-26/h5-7,14,18H,2-4,8-13H2,1H3 XOBOUIANSWIUGE-UHFFFAOYSA-N 50383440 CHEMBL2031600 Histamine H3 receptor Mus musculus 40 ChEMBL 10.1016/j.bmcl.2012.02.076 10.7270/Q2DN462S 22464130 Xiao, D; Palani, A; Sofolarides, M; Aslanian, R; West, RE; Williams, SM; Wu, RL; Hwa, J; Sondey, C; Lachowicz, J; Korfmacher, WA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50383440 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50383440&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 58430446 160862523 CHEMBL2031600 ZINC68204824 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50934654 Cc1nnc2ccc(cn12)-c1nnc(s1)N1CCC(CC1)N1CCCCC1 InChI=1S/C19H25N7S/c1-14-20-21-17-6-5-15(13-26(14)17)18-22-23-19(27-18)25-11-7-16(8-12-25)24-9-3-2-4-10-24/h5-6,13,16H,2-4,7-12H2,1H3 FKURHTCFMDOGBU-UHFFFAOYSA-N 50383442 CHEMBL2031602 Histamine H3 receptor Mus musculus 2.4 ChEMBL 10.1016/j.bmcl.2012.02.076 10.7270/Q2DN462S 22464130 Xiao, D; Palani, A; Sofolarides, M; Aslanian, R; West, RE; Williams, SM; Wu, RL; Hwa, J; Sondey, C; Lachowicz, J; Korfmacher, WA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50383442 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50383442&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 70685900 160862525 CHEMBL2031602 ZINC84652321 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50934655 C1CCN(CC1)C1CCN(CC1)c1nnc(s1)-c1cccc2cccnc12 InChI=1S/C21H25N5S/c1-2-12-25(13-3-1)17-9-14-26(15-10-17)21-24-23-20(27-21)18-8-4-6-16-7-5-11-22-19(16)18/h4-8,11,17H,1-3,9-10,12-15H2 XZVMPANJGAEMPG-UHFFFAOYSA-N 50383445 CHEMBL2031605 Histamine H3 receptor Mus musculus 7.2 ChEMBL 10.1016/j.bmcl.2012.02.076 10.7270/Q2DN462S 22464130 Xiao, D; Palani, A; Sofolarides, M; Aslanian, R; West, RE; Williams, SM; Wu, RL; Hwa, J; Sondey, C; Lachowicz, J; Korfmacher, WA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50383445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50383445&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 45377641 160862528 CHEMBL2031605 ZINC84652323 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50934656 O=c1ccoc2ccc(cc12)-c1nnc(s1)N1CCC(CC1)N1CCCCC1 InChI=1S/C21H24N4O2S/c26-18-8-13-27-19-5-4-15(14-17(18)19)20-22-23-21(28-20)25-11-6-16(7-12-25)24-9-2-1-3-10-24/h4-5,8,13-14,16H,1-3,6-7,9-12H2 PNZDIUZVTSJTRC-UHFFFAOYSA-N 50383456 CHEMBL2031616 Histamine H3 receptor Mus musculus 12 ChEMBL 10.1016/j.bmcl.2012.02.076 10.7270/Q2DN462S 22464130 Xiao, D; Palani, A; Sofolarides, M; Aslanian, R; West, RE; Williams, SM; Wu, RL; Hwa, J; Sondey, C; Lachowicz, J; Korfmacher, WA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50383456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50383456&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 58430749 160862539 CHEMBL2031616 ZINC84634124 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50934657 O=c1ccnc2ccc(cn12)-c1nnc(s1)N1CCC(CC1)N1CCCCC1 InChI=1S/C20H24N6OS/c27-18-6-9-21-17-5-4-15(14-26(17)18)19-22-23-20(28-19)25-12-7-16(8-13-25)24-10-2-1-3-11-24/h4-6,9,14,16H,1-3,7-8,10-13H2 ZLLSMIOKPQAISK-UHFFFAOYSA-N 50383458 CHEMBL2031618 Histamine H3 receptor Mus musculus 25 ChEMBL 10.1016/j.bmcl.2012.02.076 10.7270/Q2DN462S 22464130 Xiao, D; Palani, A; Sofolarides, M; Aslanian, R; West, RE; Williams, SM; Wu, RL; Hwa, J; Sondey, C; Lachowicz, J; Korfmacher, WA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50383458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50383458&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 58430604 160862541 CHEMBL2031618 ZINC84758533 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50934658 O=c1ccnc2c(cccn12)-c1nnc(s1)N1CCC(CC1)N1CCCCC1 InChI=1S/C20H24N6OS/c27-17-6-9-21-18-16(5-4-12-26(17)18)19-22-23-20(28-19)25-13-7-15(8-14-25)24-10-2-1-3-11-24/h4-6,9,12,15H,1-3,7-8,10-11,13-14H2 NAMFPZSGABLQTE-UHFFFAOYSA-N 50383459 CHEMBL2031619 Histamine H3 receptor Mus musculus 2.6 ChEMBL 10.1016/j.bmcl.2012.02.076 10.7270/Q2DN462S 22464130 Xiao, D; Palani, A; Sofolarides, M; Aslanian, R; West, RE; Williams, SM; Wu, RL; Hwa, J; Sondey, C; Lachowicz, J; Korfmacher, WA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50383459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50383459&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 45376015 160862542 CHEMBL2031619 ZINC84757213 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50942031 C1CCN(CC1)C1CCN(CC1)c1nnc(s1)N1CCOC(C1)c1ccccn1 InChI=1S/C21H30N6OS/c1-4-10-25(11-5-1)17-7-12-26(13-8-17)20-23-24-21(29-20)27-14-15-28-19(16-27)18-6-2-3-9-22-18/h2-3,6,9,17,19H,1,4-5,7-8,10-16H2 KLHCFRHKLZKQGQ-UHFFFAOYSA-N 50386346 CHEMBL2048594 Histamine H3 receptor Mus musculus 4 ChEMBL 10.1021/ml200250t 10.7270/Q2736S0M 24900450 Rao, AU; Shao, N; Aslanian, RG; Chan, TY; Degrado, SJ; Wang, L; McKittrick, B; Senior, M; West, RE; Williams, SM; Wu, RL; Hwa, J; Patel, B; Zheng, S; Sondey, C; Palani, A TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50386346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50386346&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 57384004 160865429 CHEMBL2048594 ZINC84651875 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50942032 C1CCN(CC1)C1CCN(CC1)c1nnc(s1)N1CCOC(C1)c1ccccn1 InChI=1S/C21H30N6OS/c1-4-10-25(11-5-1)17-7-12-26(13-8-17)20-23-24-21(29-20)27-14-15-28-19(16-27)18-6-2-3-9-22-18/h2-3,6,9,17,19H,1,4-5,7-8,10-16H2 KLHCFRHKLZKQGQ-UHFFFAOYSA-N 50386346 CHEMBL2048594 Histamine H3 receptor Mus musculus 4.00 ChEMBL 10.1021/ml200250t 10.7270/Q2736S0M 24900450 Rao, AU; Shao, N; Aslanian, RG; Chan, TY; Degrado, SJ; Wang, L; McKittrick, B; Senior, M; West, RE; Williams, SM; Wu, RL; Hwa, J; Patel, B; Zheng, S; Sondey, C; Palani, A TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50386346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50386346&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 57384004 160865429 CHEMBL2048594 ZINC84651875 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50942033 C1CCN(CC1)C1CCN(CC1)c1nnc(s1)N1CCOC(C1)c1cnccn1 InChI=1S/C20H29N7OS/c1-2-8-25(9-3-1)16-4-10-26(11-5-16)19-23-24-20(29-19)27-12-13-28-18(15-27)17-14-21-6-7-22-17/h6-7,14,16,18H,1-5,8-13,15H2 KMZJXYXFZMVEKV-UHFFFAOYSA-N 50386347 CHEMBL2048595 Histamine H3 receptor Mus musculus 16 ChEMBL 10.1021/ml200250t 10.7270/Q2736S0M 24900450 Rao, AU; Shao, N; Aslanian, RG; Chan, TY; Degrado, SJ; Wang, L; McKittrick, B; Senior, M; West, RE; Williams, SM; Wu, RL; Hwa, J; Patel, B; Zheng, S; Sondey, C; Palani, A TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50386347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50386347&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 62705252 160865430 CHEMBL2048595 ZINC84652198 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50942034 C1CCN(CC1)C1CCN(CC1)c1nnc(s1)N1CCOC(C1)c1ccccn1 InChI=1S/C21H30N6OS/c1-4-10-25(11-5-1)17-7-12-26(13-8-17)20-23-24-21(29-20)27-14-15-28-19(16-27)18-6-2-3-9-22-18/h2-3,6,9,17,19H,1,4-5,7-8,10-16H2 KLHCFRHKLZKQGQ-UHFFFAOYSA-N 50386346 CHEMBL2048594 Histamine H3 receptor Mus musculus 67.0 ChEMBL 10.1021/ml200250t 10.7270/Q2736S0M 24900450 Rao, AU; Shao, N; Aslanian, RG; Chan, TY; Degrado, SJ; Wang, L; McKittrick, B; Senior, M; West, RE; Williams, SM; Wu, RL; Hwa, J; Patel, B; Zheng, S; Sondey, C; Palani, A TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50386346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50386346&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 57384004 160865429 CHEMBL2048594 ZINC84651875 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50942035 OC1(CCCN(C1)c1nnc(s1)N1CCC(CC1)N1CCCCC1)c1ncccn1 InChI=1S/C21H31N7OS/c29-21(18-22-9-5-10-23-18)8-4-13-28(16-21)20-25-24-19(30-20)27-14-6-17(7-15-27)26-11-2-1-3-12-26/h5,9-10,17,29H,1-4,6-8,11-16H2 WVCQFPYIAZALNI-UHFFFAOYSA-N 50386348 CHEMBL2048593 Histamine H3 receptor Mus musculus 77 ChEMBL 10.1021/ml200250t 10.7270/Q2736S0M 24900450 Rao, AU; Shao, N; Aslanian, RG; Chan, TY; Degrado, SJ; Wang, L; McKittrick, B; Senior, M; West, RE; Williams, SM; Wu, RL; Hwa, J; Patel, B; Zheng, S; Sondey, C; Palani, A TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50386348 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50386348&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 62705251 160865431 CHEMBL2048593 ZINC84651873 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50942036 OC1(CCCN(C1)c1nnc(s1)N1CCC(CC1)N1CCCCC1)c1ccccn1 InChI=1S/C22H32N6OS/c29-22(19-7-2-3-11-23-19)10-6-14-28(17-22)21-25-24-20(30-21)27-15-8-18(9-16-27)26-12-4-1-5-13-26/h2-3,7,11,18,29H,1,4-6,8-10,12-17H2 GJPYKVNDRRCAEC-UHFFFAOYSA-N 50386349 CHEMBL2048591 Histamine H3 receptor Mus musculus 55 ChEMBL 10.1021/ml200250t 10.7270/Q2736S0M 24900450 Rao, AU; Shao, N; Aslanian, RG; Chan, TY; Degrado, SJ; Wang, L; McKittrick, B; Senior, M; West, RE; Williams, SM; Wu, RL; Hwa, J; Patel, B; Zheng, S; Sondey, C; Palani, A TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50386349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50386349&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 62705249 160865432 CHEMBL2048591 ZINC84651869 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50942037 COC1(CCCN(C1)c1nnc(s1)N1CCC(CC1)N1CCCCC1)c1ccccn1 InChI=1S/C23H34N6OS/c1-30-23(20-8-3-4-12-24-20)11-7-15-29(18-23)22-26-25-21(31-22)28-16-9-19(10-17-28)27-13-5-2-6-14-27/h3-4,8,12,19H,2,5-7,9-11,13-18H2,1H3 MMDISRMOZJISAM-UHFFFAOYSA-N 50386350 CHEMBL2048590 Histamine H3 receptor Mus musculus 54 ChEMBL 10.1021/ml200250t 10.7270/Q2736S0M 24900450 Rao, AU; Shao, N; Aslanian, RG; Chan, TY; Degrado, SJ; Wang, L; McKittrick, B; Senior, M; West, RE; Williams, SM; Wu, RL; Hwa, J; Patel, B; Zheng, S; Sondey, C; Palani, A TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50386350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50386350&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 62705091 160865433 CHEMBL2048590 ZINC84651867 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50942038 C1CCN(CC1)C1CCN(CC1)c1nnc(s1)N1CCCC(=C1)c1ccccn1 InChI=1S/C22H30N6S/c1-4-12-26(13-5-1)19-9-15-27(16-10-19)21-24-25-22(29-21)28-14-6-7-18(17-28)20-8-2-3-11-23-20/h2-3,8,11,17,19H,1,4-7,9-10,12-16H2 KGTSVLOKRNDHFU-UHFFFAOYSA-N 50386351 CHEMBL2048589 Histamine H3 receptor Mus musculus 5 ChEMBL 10.1021/ml200250t 10.7270/Q2736S0M 24900450 Rao, AU; Shao, N; Aslanian, RG; Chan, TY; Degrado, SJ; Wang, L; McKittrick, B; Senior, M; West, RE; Williams, SM; Wu, RL; Hwa, J; Patel, B; Zheng, S; Sondey, C; Palani, A TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50386351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50386351&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 62705090 160865434 CHEMBL2048589 ZINC84651865 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50942039 C1CCN(CC1)C1CCN(CC1)c1nnc(s1)N1CCC=C(C1)c1ncccn1 InChI=1S/C21H29N7S/c1-2-11-26(12-3-1)18-7-14-27(15-8-18)20-24-25-21(29-20)28-13-4-6-17(16-28)19-22-9-5-10-23-19/h5-6,9-10,18H,1-4,7-8,11-16H2 YOXJNCOFPRKZNF-UHFFFAOYSA-N 50386352 CHEMBL2048588 Histamine H3 receptor Mus musculus 44 ChEMBL 10.1021/ml200250t 10.7270/Q2736S0M 24900450 Rao, AU; Shao, N; Aslanian, RG; Chan, TY; Degrado, SJ; Wang, L; McKittrick, B; Senior, M; West, RE; Williams, SM; Wu, RL; Hwa, J; Patel, B; Zheng, S; Sondey, C; Palani, A TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50386352 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50386352&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 62705089 160865435 CHEMBL2048588 ZINC84652883 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50942040 C1CCN(CC1)C1CCN(CC1)c1nnc(s1)N1CCC=C(C1)c1ccccn1 InChI=1S/C22H30N6S/c1-4-12-26(13-5-1)19-9-15-27(16-10-19)21-24-25-22(29-21)28-14-6-7-18(17-28)20-8-2-3-11-23-20/h2-3,7-8,11,19H,1,4-6,9-10,12-17H2 LCTRTTFIEYYPEI-UHFFFAOYSA-N 50386353 CHEMBL2048587 Histamine H3 receptor Mus musculus 49 ChEMBL 10.1021/ml200250t 10.7270/Q2736S0M 24900450 Rao, AU; Shao, N; Aslanian, RG; Chan, TY; Degrado, SJ; Wang, L; McKittrick, B; Senior, M; West, RE; Williams, SM; Wu, RL; Hwa, J; Patel, B; Zheng, S; Sondey, C; Palani, A TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50386353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50386353&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 62705088 160865436 CHEMBL2048587 ZINC84652882 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50942041 CC1CN(CC(C)O1)c1nnc(s1)N1CCC(CC1)N1CCCCC1 InChI=1S/C18H31N5OS/c1-14-12-23(13-15(2)24-14)18-20-19-17(25-18)22-10-6-16(7-11-22)21-8-4-3-5-9-21/h14-16H,3-13H2,1-2H3 BPOGPSWQWXFRCB-UHFFFAOYSA-N 50386354 CHEMBL2048586 Histamine H3 receptor Mus musculus 35 ChEMBL 10.1021/ml200250t 10.7270/Q2736S0M 24900450 Rao, AU; Shao, N; Aslanian, RG; Chan, TY; Degrado, SJ; Wang, L; McKittrick, B; Senior, M; West, RE; Williams, SM; Wu, RL; Hwa, J; Patel, B; Zheng, S; Sondey, C; Palani, A TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50386354 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50386354&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 58430454 160865437 CHEMBL2048586 ZINC84652881 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50942042 FC1CCCN(C1)c1nnc(s1)N1CCC(CC1)N1CCCCC1 InChI=1S/C17H28FN5S/c18-14-5-4-10-23(13-14)17-20-19-16(24-17)22-11-6-15(7-12-22)21-8-2-1-3-9-21/h14-15H,1-13H2 UUFSQJFGDUISMZ-UHFFFAOYSA-N 50386355 CHEMBL2048585 Histamine H3 receptor Mus musculus 56 ChEMBL 10.1021/ml200250t 10.7270/Q2736S0M 24900450 Rao, AU; Shao, N; Aslanian, RG; Chan, TY; Degrado, SJ; Wang, L; McKittrick, B; Senior, M; West, RE; Williams, SM; Wu, RL; Hwa, J; Patel, B; Zheng, S; Sondey, C; Palani, A TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50386355 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50386355&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 62705087 160865438 CHEMBL2048585 ZINC84670363 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50942043 OC1CCCN(C1)c1nnc(s1)N1CCC(CC1)N1CCCCC1 InChI=1S/C17H29N5OS/c23-15-5-4-10-22(13-15)17-19-18-16(24-17)21-11-6-14(7-12-21)20-8-2-1-3-9-20/h14-15,23H,1-13H2 LSGIMSTZCFZIKC-UHFFFAOYSA-N 50386356 CHEMBL2048584 Histamine H3 receptor Mus musculus 68 ChEMBL 10.1021/ml200250t 10.7270/Q2736S0M 24900450 Rao, AU; Shao, N; Aslanian, RG; Chan, TY; Degrado, SJ; Wang, L; McKittrick, B; Senior, M; West, RE; Williams, SM; Wu, RL; Hwa, J; Patel, B; Zheng, S; Sondey, C; Palani, A TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50386356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50386356&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 62707527 160865439 CHEMBL2048584 ZINC84652878 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50942044 COC1CCCN(C1)c1nnc(s1)N1CCC(CC1)N1CCCCC1 InChI=1S/C18H31N5OS/c1-24-16-6-5-11-23(14-16)18-20-19-17(25-18)22-12-7-15(8-13-22)21-9-3-2-4-10-21/h15-16H,2-14H2,1H3 IJQMPJJDNNFMLK-UHFFFAOYSA-N 50386357 CHEMBL2048583 Histamine H3 receptor Mus musculus 46 ChEMBL 10.1021/ml200250t 10.7270/Q2736S0M 24900450 Rao, AU; Shao, N; Aslanian, RG; Chan, TY; Degrado, SJ; Wang, L; McKittrick, B; Senior, M; West, RE; Williams, SM; Wu, RL; Hwa, J; Patel, B; Zheng, S; Sondey, C; Palani, A TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50386357 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50386357&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 62707526 160865440 CHEMBL2048583 ZINC84652876 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50942045 C1CCN(CC1)C1CCN(CC1)c1nnc(s1)N1CCCC(C1)c1ccccc1 InChI=1S/C23H33N5S/c1-3-8-19(9-4-1)20-10-7-15-28(18-20)23-25-24-22(29-23)27-16-11-21(12-17-27)26-13-5-2-6-14-26/h1,3-4,8-9,20-21H,2,5-7,10-18H2 UKXQJJDASUHIPZ-UHFFFAOYSA-N 50386358 CHEMBL2048582 Histamine H3 receptor Mus musculus 110 ChEMBL 10.1021/ml200250t 10.7270/Q2736S0M 24900450 Rao, AU; Shao, N; Aslanian, RG; Chan, TY; Degrado, SJ; Wang, L; McKittrick, B; Senior, M; West, RE; Williams, SM; Wu, RL; Hwa, J; Patel, B; Zheng, S; Sondey, C; Palani, A TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50386358 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50386358&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 45377639 160865441 CHEMBL2048582 ZINC84759303 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50942046 FC1(F)CCN(CC1)c1nnc(s1)N1CCC(CC1)N1CCCCC1 InChI=1S/C17H27F2N5S/c18-17(19)6-12-24(13-7-17)16-21-20-15(25-16)23-10-4-14(5-11-23)22-8-2-1-3-9-22/h14H,1-13H2 ZXSYUOXJWQFKBR-UHFFFAOYSA-N 50386359 CHEMBL2048581 Histamine H3 receptor Mus musculus 18 ChEMBL 10.1021/ml200250t 10.7270/Q2736S0M 24900450 Rao, AU; Shao, N; Aslanian, RG; Chan, TY; Degrado, SJ; Wang, L; McKittrick, B; Senior, M; West, RE; Williams, SM; Wu, RL; Hwa, J; Patel, B; Zheng, S; Sondey, C; Palani, A TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50386359 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50386359&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 58430625 160865442 CHEMBL2048581 ZINC84652823 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50942047 FC1(F)CCN(C1)c1nnc(s1)N1CCC(CC1)N1CCCCC1 InChI=1S/C16H25F2N5S/c17-16(18)6-11-23(12-16)15-20-19-14(24-15)22-9-4-13(5-10-22)21-7-2-1-3-8-21/h13H,1-12H2 NIJROOKCOFTEPG-UHFFFAOYSA-N 50386360 CHEMBL2048414 Histamine H3 receptor Mus musculus 61 ChEMBL 10.1021/ml200250t 10.7270/Q2736S0M 24900450 Rao, AU; Shao, N; Aslanian, RG; Chan, TY; Degrado, SJ; Wang, L; McKittrick, B; Senior, M; West, RE; Williams, SM; Wu, RL; Hwa, J; Patel, B; Zheng, S; Sondey, C; Palani, A TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50386360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50386360&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 58430524 160865443 CHEMBL2048414 ZINC84670987 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50942048 O=C1CCCCN1c1nnc(s1)N1CCC(CC1)N1CCCCC1 InChI=1S/C17H27N5OS/c23-15-6-2-5-11-22(15)17-19-18-16(24-17)21-12-7-14(8-13-21)20-9-3-1-4-10-20/h14H,1-13H2 GTDIJQCEVHTETC-UHFFFAOYSA-N 50386361 CHEMBL2048413 Histamine H3 receptor Mus musculus 120 ChEMBL 10.1021/ml200250t 10.7270/Q2736S0M 24900450 Rao, AU; Shao, N; Aslanian, RG; Chan, TY; Degrado, SJ; Wang, L; McKittrick, B; Senior, M; West, RE; Williams, SM; Wu, RL; Hwa, J; Patel, B; Zheng, S; Sondey, C; Palani, A TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50386361 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50386361&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 62707525 160865444 CHEMBL2048413 ZINC84670986 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50942049 O=C1N(CCCN1c1ccccc1)c1nnc(s1)N1CCC(CC1)N1CCCCC1 InChI=1S/C22H30N6OS/c29-22-27(19-8-3-1-4-9-19)14-7-15-28(22)21-24-23-20(30-21)26-16-10-18(11-17-26)25-12-5-2-6-13-25/h1,3-4,8-9,18H,2,5-7,10-17H2 OWQZUXOHJOEVBY-UHFFFAOYSA-N 50386362 CHEMBL2048412 Histamine H3 receptor Mus musculus 32 ChEMBL 10.1021/ml200250t 10.7270/Q2736S0M 24900450 Rao, AU; Shao, N; Aslanian, RG; Chan, TY; Degrado, SJ; Wang, L; McKittrick, B; Senior, M; West, RE; Williams, SM; Wu, RL; Hwa, J; Patel, B; Zheng, S; Sondey, C; Palani, A TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50386362 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50386362&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 62707524 160865445 CHEMBL2048412 ZINC84670985 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50942050 O=C1N(CCN1c1nnc(s1)N1CCC(CC1)N1CCCCC1)C1CCCC1 InChI=1S/C20H32N6OS/c27-20-25(17-6-2-3-7-17)14-15-26(20)19-22-21-18(28-19)24-12-8-16(9-13-24)23-10-4-1-5-11-23/h16-17H,1-15H2 KLQXIWPAVNHWBL-UHFFFAOYSA-N 50386363 CHEMBL2048411 Histamine H3 receptor Mus musculus 53 ChEMBL 10.1021/ml200250t 10.7270/Q2736S0M 24900450 Rao, AU; Shao, N; Aslanian, RG; Chan, TY; Degrado, SJ; Wang, L; McKittrick, B; Senior, M; West, RE; Williams, SM; Wu, RL; Hwa, J; Patel, B; Zheng, S; Sondey, C; Palani, A TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50386363 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50386363&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 58430814 160865446 CHEMBL2048411 ZINC84670984 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50942051 O=C(NC1CCCC1)Nc1nnc(s1)N1CCC(CC1)N1CCCCC1 InChI=1S/C18H30N6OS/c25-16(19-14-6-2-3-7-14)20-17-21-22-18(26-17)24-12-8-15(9-13-24)23-10-4-1-5-11-23/h14-15H,1-13H2,(H2,19,20,21,25) UEPMBFDUHOWDCI-UHFFFAOYSA-N 50333504 1-(5-(1,4'-bipiperidin-1'-yl)-1,3,4-thiadiazol-2-yl)-3-cyclopentylurea::CHEMBL1641821 Histamine H3 receptor Mus musculus 47 ChEMBL 10.1021/ml200250t 10.7270/Q2736S0M 24900450 Rao, AU; Shao, N; Aslanian, RG; Chan, TY; Degrado, SJ; Wang, L; McKittrick, B; Senior, M; West, RE; Williams, SM; Wu, RL; Hwa, J; Patel, B; Zheng, S; Sondey, C; Palani, A TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50333504 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50333504&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 53317856 125083606 CHEMBL1641821 ZINC66259898 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50942072 FC1(CCCN(C1)c1nnc(s1)N1CCC(CC1)N1CCCCC1)c1ccccn1 InChI=1S/C22H31FN6S/c23-22(19-7-2-3-11-24-19)10-6-14-29(17-22)21-26-25-20(30-21)28-15-8-18(9-16-28)27-12-4-1-5-13-27/h2-3,7,11,18H,1,4-6,8-10,12-17H2 GEJRQPROBMDGHW-UHFFFAOYSA-N 50386364 CHEMBL2048592 Histamine H3 receptor Mus musculus 7 ChEMBL 10.1021/ml200250t 10.7270/Q2736S0M 24900450 Rao, AU; Shao, N; Aslanian, RG; Chan, TY; Degrado, SJ; Wang, L; McKittrick, B; Senior, M; West, RE; Williams, SM; Wu, RL; Hwa, J; Patel, B; Zheng, S; Sondey, C; Palani, A TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50386364 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50386364&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 62705250 160865447 CHEMBL2048592 ZINC84651871 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 51079711 Nc1cc(CN2CCC(F)(CC2)C(=O)N2CCC(CC2)N2Cc3ccc(F)cc3C2)ccn1 InChI=1S/C25H31F2N5O/c26-21-2-1-19-16-32(17-20(19)14-21)22-4-9-31(10-5-22)24(33)25(27)6-11-30(12-7-25)15-18-3-8-29-23(28)13-18/h1-3,8,13-14,22H,4-7,9-12,15-17H2,(H2,28,29) MLBBOYBRPZGZGW-UHFFFAOYSA-N 50441501 CHEMBL2436630 Histamine H3 receptor Mus musculus 7.0 ChEMBL 10.1016/j.bmcl.2013.08.013 10.7270/Q2FJ2J67 24035485 de Lera Ruiz, M; Zheng, J; Berlin, MY; McCormick, KD; Aslanian, RG; West, R; Hwa, J; Lachowicz, J; van Heek, M Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441501 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441501&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 44622418 175453818 CHEMBL2436630 ZINC96285174 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 51079712 Nc1cc(CN2CCC(F)(CC2)C(=O)N2CCC(CC2)N2Cc3ccccc3C2)ccn1 InChI=1S/C25H32FN5O/c26-25(8-13-29(14-9-25)16-19-5-10-28-23(27)15-19)24(32)30-11-6-22(7-12-30)31-17-20-3-1-2-4-21(20)18-31/h1-5,10,15,22H,6-9,11-14,16-18H2,(H2,27,28) BYPZYWWDUSSBJF-UHFFFAOYSA-N 50441502 CHEMBL2436629 Histamine H3 receptor Mus musculus 4.0 ChEMBL 10.1016/j.bmcl.2013.08.013 10.7270/Q2FJ2J67 24035485 de Lera Ruiz, M; Zheng, J; Berlin, MY; McCormick, KD; Aslanian, RG; West, R; Hwa, J; Lachowicz, J; van Heek, M Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441502 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441502&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 44622417 175453819 CHEMBL2436629 ZINC68200741 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 51079713 Nc1cc(CN2CCC(F)(CC2)C(=O)N2CCC(CC2)N2CCc3ccc(cc3C2)C#N)ccn1 InChI=1S/C27H33FN6O/c28-27(7-13-32(14-8-27)18-21-3-9-31-25(30)16-21)26(35)33-11-5-24(6-12-33)34-10-4-22-2-1-20(17-29)15-23(22)19-34/h1-3,9,15-16,24H,4-8,10-14,18-19H2,(H2,30,31) WAEWFNQGFKVNEU-UHFFFAOYSA-N 50441503 CHEMBL2436628 Histamine H3 receptor Mus musculus 2.0 ChEMBL 10.1016/j.bmcl.2013.08.013 10.7270/Q2FJ2J67 24035485 de Lera Ruiz, M; Zheng, J; Berlin, MY; McCormick, KD; Aslanian, RG; West, R; Hwa, J; Lachowicz, J; van Heek, M Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441503 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441503&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 44603096 175453820 CHEMBL2436628 ZINC68200726 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 51079714 Nc1cc(CN2CCC(F)(CC2)C(=O)N2CCC(CC2)N2CCc3ccccc3C2)ccn1 InChI=1S/C26H34FN5O/c27-26(9-15-30(16-10-26)18-20-5-11-29-24(28)17-20)25(33)31-13-7-23(8-14-31)32-12-6-21-3-1-2-4-22(21)19-32/h1-5,11,17,23H,6-10,12-16,18-19H2,(H2,28,29) STNAHDQLZLCSLS-UHFFFAOYSA-N 50441504 CHEMBL2436627 Histamine H3 receptor Mus musculus 4.0 ChEMBL 10.1016/j.bmcl.2013.08.013 10.7270/Q2FJ2J67 24035485 de Lera Ruiz, M; Zheng, J; Berlin, MY; McCormick, KD; Aslanian, RG; West, R; Hwa, J; Lachowicz, J; van Heek, M Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441504 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441504&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 44622416 175453821 CHEMBL2436627 ZINC68200738 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 51079715 Nc1cc(CN2CCC(F)(CC2)C(=O)N2CCC(CC2)N2CCNc3ccccc3C2)ccn1 InChI=1S/C26H35FN6O/c27-26(8-14-31(15-9-26)18-20-5-10-30-24(28)17-20)25(34)32-12-6-22(7-13-32)33-16-11-29-23-4-2-1-3-21(23)19-33/h1-5,10,17,22,29H,6-9,11-16,18-19H2,(H2,28,30) NVORSIAIADQRIC-UHFFFAOYSA-N 50441505 CHEMBL2436626 Histamine H3 receptor Mus musculus 3.0 ChEMBL 10.1016/j.bmcl.2013.08.013 10.7270/Q2FJ2J67 24035485 de Lera Ruiz, M; Zheng, J; Berlin, MY; McCormick, KD; Aslanian, RG; West, R; Hwa, J; Lachowicz, J; van Heek, M Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441505 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441505&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 44622342 175453822 CHEMBL2436626 ZINC68200735 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 51079716 COc1ccc2CN(CCCc2c1)C1CCN(CC1)C(=O)C1(F)CCN(Cc2ccnc(N)c2)CC1 InChI=1S/C28H38FN5O2/c1-36-25-5-4-23-20-34(12-2-3-22(23)18-25)24-7-13-33(14-8-24)27(35)28(29)9-15-32(16-10-28)19-21-6-11-31-26(30)17-21/h4-6,11,17-18,24H,2-3,7-10,12-16,19-20H2,1H3,(H2,30,31) BMWUIIPULBWCPO-UHFFFAOYSA-N 50441506 CHEMBL2436625 Histamine H3 receptor Mus musculus 3.0 ChEMBL 10.1016/j.bmcl.2013.08.013 10.7270/Q2FJ2J67 24035485 de Lera Ruiz, M; Zheng, J; Berlin, MY; McCormick, KD; Aslanian, RG; West, R; Hwa, J; Lachowicz, J; van Heek, M Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441506 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441506&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 44622341 175453823 CHEMBL2436625 ZINC96285175 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 51079717 COc1ccc2CCCN(Cc2c1)C1CCN(CC1)C(=O)C1(F)CCN(Cc2ccnc(N)c2)CC1 InChI=1S/C28H38FN5O2/c1-36-25-5-4-22-3-2-12-34(20-23(22)18-25)24-7-13-33(14-8-24)27(35)28(29)9-15-32(16-10-28)19-21-6-11-31-26(30)17-21/h4-6,11,17-18,24H,2-3,7-10,12-16,19-20H2,1H3,(H2,30,31) PTPOPPWALKSUMU-UHFFFAOYSA-N 50441507 CHEMBL2436624 Histamine H3 receptor Mus musculus 4.0 ChEMBL 10.1016/j.bmcl.2013.08.013 10.7270/Q2FJ2J67 24035485 de Lera Ruiz, M; Zheng, J; Berlin, MY; McCormick, KD; Aslanian, RG; West, R; Hwa, J; Lachowicz, J; van Heek, M Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441507 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441507&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 44622340 175453824 CHEMBL2436624 ZINC96285176 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 51079718 Nc1cc(CN2CCC(F)(CC2)C(=O)N2CCC(CC2)N2CCc3ccccc3CC2)ccn1 InChI=1S/C27H36FN5O/c28-27(10-17-31(18-11-27)20-21-5-12-30-25(29)19-21)26(34)33-15-8-24(9-16-33)32-13-6-22-3-1-2-4-23(22)7-14-32/h1-5,12,19,24H,6-11,13-18,20H2,(H2,29,30) ROIWDPBJIDVJNS-UHFFFAOYSA-N 50441509 CHEMBL2436622 Histamine H3 receptor Mus musculus 3.0 ChEMBL 10.1016/j.bmcl.2013.08.013 10.7270/Q2FJ2J67 24035485 de Lera Ruiz, M; Zheng, J; Berlin, MY; McCormick, KD; Aslanian, RG; West, R; Hwa, J; Lachowicz, J; van Heek, M Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441509&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 44622339 175453826 CHEMBL2436622 ZINC68200732 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 51079719 Nc1cc(CN2CCC(F)(CC2)C(=O)N2CCC(CC2)N2CCCc3ccccc3C2)ccn1 InChI=1S/C27H36FN5O/c28-27(10-16-31(17-11-27)19-21-7-12-30-25(29)18-21)26(34)32-14-8-24(9-15-32)33-13-3-6-22-4-1-2-5-23(22)20-33/h1-2,4-5,7,12,18,24H,3,6,8-11,13-17,19-20H2,(H2,29,30) WXNHTAGZWUGZCQ-UHFFFAOYSA-N 50441508 CHEMBL2436623 Histamine H3 receptor Mus musculus 115 ChEMBL 10.1016/j.bmcl.2013.08.013 10.7270/Q2FJ2J67 24035485 de Lera Ruiz, M; Zheng, J; Berlin, MY; McCormick, KD; Aslanian, RG; West, R; Hwa, J; Lachowicz, J; van Heek, M Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441508 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441508&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 44622338 175453825 CHEMBL2436623 ZINC96285177 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 51079720 Cc1nnc2CN(C3CCN(CC3)C(=O)C3(F)CCN(Cc4ccnc(N)c4)CC3)C(=O)c3ccsc3-n12 InChI=1S/C26H31FN8O2S/c1-17-30-31-22-16-34(23(36)20-5-13-38-24(20)35(17)22)19-3-9-33(10-4-19)25(37)26(27)6-11-32(12-7-26)15-18-2-8-29-21(28)14-18/h2,5,8,13-14,19H,3-4,6-7,9-12,15-16H2,1H3,(H2,28,29) CTGSDVZVJSPCBE-UHFFFAOYSA-N 50441510 CHEMBL2436621 Histamine H3 receptor Mus musculus 70 ChEMBL 10.1016/j.bmcl.2013.08.013 10.7270/Q2FJ2J67 24035485 de Lera Ruiz, M; Zheng, J; Berlin, MY; McCormick, KD; Aslanian, RG; West, R; Hwa, J; Lachowicz, J; van Heek, M Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441510 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441510&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 72375121 175453827 CHEMBL2436621 ZINC96285178 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 51079721 Cc1nnc2CN(Cc3ccsc3-n12)C1CCN(CC1)C(=O)C1(F)CCN(Cc2ccnc(N)c2)CC1 InChI=1S/C26H33FN8OS/c1-18-30-31-23-17-34(16-20-5-13-37-24(20)35(18)23)21-3-9-33(10-4-21)25(36)26(27)6-11-32(12-7-26)15-19-2-8-29-22(28)14-19/h2,5,8,13-14,21H,3-4,6-7,9-12,15-17H2,1H3,(H2,28,29) UADYGGCZODNWRD-UHFFFAOYSA-N 50441511 CHEMBL2436620 Histamine H3 receptor Mus musculus 2.0 ChEMBL 10.1016/j.bmcl.2013.08.013 10.7270/Q2FJ2J67 24035485 de Lera Ruiz, M; Zheng, J; Berlin, MY; McCormick, KD; Aslanian, RG; West, R; Hwa, J; Lachowicz, J; van Heek, M Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441511 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441511&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 72375120 175453828 CHEMBL2436620 ZINC96285179 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 51079722 Nc1cc(CN2CCC(F)(CC2)C(=O)N2CCC(CC2)N2c3ccccc3Sc3cccnc23)ccn1 InChI=1S/C28H31FN6OS/c29-28(10-16-33(17-11-28)19-20-7-13-31-25(30)18-20)27(36)34-14-8-21(9-15-34)35-22-4-1-2-5-23(22)37-24-6-3-12-32-26(24)35/h1-7,12-13,18,21H,8-11,14-17,19H2,(H2,30,31) PFMVLMOJJHQYJP-UHFFFAOYSA-N 50441515 CHEMBL2436619 Histamine H3 receptor Mus musculus 26 ChEMBL 10.1016/j.bmcl.2013.08.013 10.7270/Q2FJ2J67 24035485 de Lera Ruiz, M; Zheng, J; Berlin, MY; McCormick, KD; Aslanian, RG; West, R; Hwa, J; Lachowicz, J; van Heek, M Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441515 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441515&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 44816866 175453832 CHEMBL2436619 ZINC96285182 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 51079723 Nc1cc(CN2CCC(F)(CC2)C(=O)N2CCC(CC2)N2c3ccccc3Sc3ccc(cc23)C(F)(F)F)ccn1 InChI=1S/C30H31F4N5OS/c31-29(10-15-37(16-11-29)19-20-7-12-36-27(35)17-20)28(40)38-13-8-22(9-14-38)39-23-3-1-2-4-25(23)41-26-6-5-21(18-24(26)39)30(32,33)34/h1-7,12,17-18,22H,8-11,13-16,19H2,(H2,35,36) PWJAOGFKLATTAX-UHFFFAOYSA-N 50441516 CHEMBL2436618 Histamine H3 receptor Mus musculus 51 ChEMBL 10.1016/j.bmcl.2013.08.013 10.7270/Q2FJ2J67 24035485 de Lera Ruiz, M; Zheng, J; Berlin, MY; McCormick, KD; Aslanian, RG; West, R; Hwa, J; Lachowicz, J; van Heek, M Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441516 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441516&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 44816517 175453833 CHEMBL2436618 ZINC96285183 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 51079724 Nc1cc(CN2CCC(F)(CC2)C(=O)N2CCC(CC2)N2Cc3ccccc3-c3ccccc3C2)ccn1 InChI=1S/C31H36FN5O/c32-31(12-17-35(18-13-31)20-23-9-14-34-29(33)19-23)30(38)36-15-10-26(11-16-36)37-21-24-5-1-3-7-27(24)28-8-4-2-6-25(28)22-37/h1-9,14,19,26H,10-13,15-18,20-22H2,(H2,33,34) NEPGOHXZJPYLLQ-UHFFFAOYSA-N 50441514 CHEMBL2436633 Histamine H3 receptor Mus musculus 4.0 ChEMBL 10.1016/j.bmcl.2013.08.013 10.7270/Q2FJ2J67 24035485 de Lera Ruiz, M; Zheng, J; Berlin, MY; McCormick, KD; Aslanian, RG; West, R; Hwa, J; Lachowicz, J; van Heek, M Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441514 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441514&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 44602971 175453831 CHEMBL2436633 ZINC68200704 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 51079725 Nc1cc(CN2CCC(F)(CC2)C(=O)N2CCC(CC2)N2Cc3ccccc3Cc3ccccc23)ccn1 InChI=1S/C31H36FN5O/c32-31(12-17-35(18-13-31)21-23-9-14-34-29(33)19-23)30(38)36-15-10-27(11-16-36)37-22-26-7-2-1-5-24(26)20-25-6-3-4-8-28(25)37/h1-9,14,19,27H,10-13,15-18,20-22H2,(H2,33,34) AUKNZSATOILHNI-UHFFFAOYSA-N 50441513 CHEMBL2436616 Histamine H3 receptor Mus musculus 44 ChEMBL 10.1016/j.bmcl.2013.08.013 10.7270/Q2FJ2J67 24035485 de Lera Ruiz, M; Zheng, J; Berlin, MY; McCormick, KD; Aslanian, RG; West, R; Hwa, J; Lachowicz, J; van Heek, M Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441513 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441513&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 44816692 175453830 CHEMBL2436616 ZINC96285181 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 51079726 Nc1cc(CN2CCC(F)(CC2)C(=O)N2CCC(CC2)N2c3ccccc3Sc3ccccc23)ccn1 InChI=1S/C29H32FN5OS/c30-29(12-17-33(18-13-29)20-21-9-14-32-27(31)19-21)28(36)34-15-10-22(11-16-34)35-23-5-1-3-7-25(23)37-26-8-4-2-6-24(26)35/h1-9,14,19,22H,10-13,15-18,20H2,(H2,31,32) CSHNEQFLMBVIPC-UHFFFAOYSA-N 50441512 CHEMBL2436617 Histamine H3 receptor Mus musculus 7.0 ChEMBL 10.1016/j.bmcl.2013.08.013 10.7270/Q2FJ2J67 24035485 de Lera Ruiz, M; Zheng, J; Berlin, MY; McCormick, KD; Aslanian, RG; West, R; Hwa, J; Lachowicz, J; van Heek, M Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441512 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441512&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 44816514 175453829 CHEMBL2436617 ZINC96285180 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 51079727 Cn1c2CCN(CCc2c2ccccc12)C1CCN(CC1)C(=O)C1(F)CCN(Cc2ccnc(N)c2)CC1 InChI=1S/C30H39FN6O/c1-34-26-5-3-2-4-24(26)25-9-16-36(17-10-27(25)34)23-7-14-37(15-8-23)29(38)30(31)11-18-35(19-12-30)21-22-6-13-33-28(32)20-22/h2-6,13,20,23H,7-12,14-19,21H2,1H3,(H2,32,33) VBAGFAWQNDYXGA-UHFFFAOYSA-N 50441500 CHEMBL2436632 Histamine H3 receptor Mus musculus 46 ChEMBL 10.1016/j.bmcl.2013.08.013 10.7270/Q2FJ2J67 24035485 de Lera Ruiz, M; Zheng, J; Berlin, MY; McCormick, KD; Aslanian, RG; West, R; Hwa, J; Lachowicz, J; van Heek, M Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441500 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441500&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 44622499 175453817 CHEMBL2436632 ZINC68200748 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 51079728 Nc1cc(CN2CCC(F)(CC2)C(=O)N2CCC(CC2)N2Cc3cccnc3C2)ccn1 InChI=1S/C24H31FN6O/c25-24(6-12-29(13-7-24)15-18-3-9-28-22(26)14-18)23(32)30-10-4-20(5-11-30)31-16-19-2-1-8-27-21(19)17-31/h1-3,8-9,14,20H,4-7,10-13,15-17H2,(H2,26,28) UCIYVMWYWYHGNV-UHFFFAOYSA-N 50441517 CHEMBL2436631 Histamine H3 receptor Mus musculus 15 ChEMBL 10.1016/j.bmcl.2013.08.013 10.7270/Q2FJ2J67 24035485 de Lera Ruiz, M; Zheng, J; Berlin, MY; McCormick, KD; Aslanian, RG; West, R; Hwa, J; Lachowicz, J; van Heek, M Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441517 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441517&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 58285100 175453834 CHEMBL2436631 ZINC96285184 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 51061786 OC(C=C)c1ccc(OCCCN2CCCCC2)cc1 InChI=1S/C17H25NO2/c1-2-17(19)15-7-9-16(10-8-15)20-14-6-13-18-11-4-3-5-12-18/h2,7-10,17,19H,1,3-6,11-14H2 QGMUPTINCBOLIA-UHFFFAOYSA-N 50433195 CHEMBL2375591 Histamine H3 receptor Mus musculus 18 ChEMBL 10.1016/j.bmcl.2013.02.118 10.7270/Q2416ZFW 23535326 Labeeuw, O; Levoin, N; Poupardin-Olivier, O; Calmels, T; Ligneau, X; Berrebi-Bertrand, I; Robert, P; Lecomte, JM; Schwartz, JC; Capet, M Bioprojet-Biotech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50433195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50433195&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 71601550 175445512 CHEMBL2375591 ZINC96258605 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 51061787 CCC(O)(CC)c1ccc(OCCCN2CCCCC2)cc1 InChI=1S/C19H31NO2/c1-3-19(21,4-2)17-9-11-18(12-10-17)22-16-8-15-20-13-6-5-7-14-20/h9-12,21H,3-8,13-16H2,1-2H3 OXDUOCLJDKRSAJ-UHFFFAOYSA-N 50433196 CHEMBL2375593 Histamine H3 receptor Mus musculus 14 ChEMBL 10.1016/j.bmcl.2013.02.118 10.7270/Q2416ZFW 23535326 Labeeuw, O; Levoin, N; Poupardin-Olivier, O; Calmels, T; Ligneau, X; Berrebi-Bertrand, I; Robert, P; Lecomte, JM; Schwartz, JC; Capet, M Bioprojet-Biotech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50433196 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50433196&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 71601692 175445513 CHEMBL2375593 ZINC96258607 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 51061788 OC1(CCCC1)c1ccc(OCCCN2CCCCC2)cc1 InChI=1S/C19H29NO2/c21-19(11-2-3-12-19)17-7-9-18(10-8-17)22-16-6-15-20-13-4-1-5-14-20/h7-10,21H,1-6,11-16H2 OVUPJCFIGACEID-UHFFFAOYSA-N 50433197 CHEMBL2375597 Histamine H3 receptor Mus musculus 7.6 ChEMBL 10.1016/j.bmcl.2013.02.118 10.7270/Q2416ZFW 23535326 Labeeuw, O; Levoin, N; Poupardin-Olivier, O; Calmels, T; Ligneau, X; Berrebi-Bertrand, I; Robert, P; Lecomte, JM; Schwartz, JC; Capet, M Bioprojet-Biotech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50433197 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50433197&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 11978736 175445514 CHEMBL2375597 ZINC96258608 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 51061789 O[C@H]1CC[C@@H](CC1)c1ccc(OCCCN2CCCCC2)cc1 InChI=1S/C20H31NO2/c22-19-9-5-17(6-10-19)18-7-11-20(12-8-18)23-16-4-15-21-13-2-1-3-14-21/h7-8,11-12,17,19,22H,1-6,9-10,13-16H2/t17-,19- VKZMICHNLVMXRJ-UAPYVXQJSA-N 50433194 CHEMBL2375587 Histamine H3 receptor Mus musculus 6.9 ChEMBL 10.1016/j.bmcl.2013.02.118 10.7270/Q2416ZFW 23535326 Labeeuw, O; Levoin, N; Poupardin-Olivier, O; Calmels, T; Ligneau, X; Berrebi-Bertrand, I; Robert, P; Lecomte, JM; Schwartz, JC; Capet, M Bioprojet-Biotech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50433194 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50433194&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 15940927 175445511 CHEMBL2375587 ZINC34775059 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 51061790 OC1CCC(Cc2ccc(OCCCN3CCCCC3)cc2)CC1 InChI=1S/C21H33NO2/c23-20-9-5-18(6-10-20)17-19-7-11-21(12-8-19)24-16-4-15-22-13-2-1-3-14-22/h7-8,11-12,18,20,23H,1-6,9-10,13-17H2 HKFWOTJVDCMHST-UHFFFAOYSA-N 50433198 CHEMBL2375588 Histamine H3 receptor Mus musculus 6.3 ChEMBL 10.1016/j.bmcl.2013.02.118 10.7270/Q2416ZFW 23535326 Labeeuw, O; Levoin, N; Poupardin-Olivier, O; Calmels, T; Ligneau, X; Berrebi-Bertrand, I; Robert, P; Lecomte, JM; Schwartz, JC; Capet, M Bioprojet-Biotech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50433198 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50433198&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 71601844 175445515 CHEMBL2375588 ZINC96258610 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 51061791 OC(CC=C)(CC=C)c1ccc(OCCCN2CCCCC2)cc1 InChI=1S/C21H31NO2/c1-3-13-21(23,14-4-2)19-9-11-20(12-10-19)24-18-8-17-22-15-6-5-7-16-22/h3-4,9-12,23H,1-2,5-8,13-18H2 SRYJREKTTRLSIX-UHFFFAOYSA-N 50433199 CHEMBL2375595 Histamine H3 receptor Mus musculus 4.3 ChEMBL 10.1016/j.bmcl.2013.02.118 10.7270/Q2416ZFW 23535326 Labeeuw, O; Levoin, N; Poupardin-Olivier, O; Calmels, T; Ligneau, X; Berrebi-Bertrand, I; Robert, P; Lecomte, JM; Schwartz, JC; Capet, M Bioprojet-Biotech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50433199 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50433199&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 11978737 175445516 CHEMBL2375595 ZINC59813035 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 51061792 CCCC(O)(CCC)c1ccc(OCCCN2CCCCC2)cc1 InChI=1S/C21H35NO2/c1-3-13-21(23,14-4-2)19-9-11-20(12-10-19)24-18-8-17-22-15-6-5-7-16-22/h9-12,23H,3-8,13-18H2,1-2H3 PETWWIOECLOXGN-UHFFFAOYSA-N 50433200 CHEMBL2375594 Histamine H3 receptor Mus musculus 2.5 ChEMBL 10.1016/j.bmcl.2013.02.118 10.7270/Q2416ZFW 23535326 Labeeuw, O; Levoin, N; Poupardin-Olivier, O; Calmels, T; Ligneau, X; Berrebi-Bertrand, I; Robert, P; Lecomte, JM; Schwartz, JC; Capet, M Bioprojet-Biotech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50433200 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50433200&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 11978735 175445517 CHEMBL2375594 ZINC96258612 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 51061793 C(COc1ccc(cc1)[C@H]1CC[C@@H](CC1)N1CCOCC1)CN1CCCCC1 InChI=1S/C24H38N2O2/c1-2-13-25(14-3-1)15-4-18-28-24-11-7-22(8-12-24)21-5-9-23(10-6-21)26-16-19-27-20-17-26/h7-8,11-12,21,23H,1-6,9-10,13-20H2/t21-,23- NFMCJKWXWBIFGH-AFARHQOCSA-N 50352090 CHEMBL1824241 Histamine H3 receptor Mus musculus 1.6 ChEMBL 10.1016/j.bmcl.2013.02.118 10.7270/Q2416ZFW 23535326 Labeeuw, O; Levoin, N; Poupardin-Olivier, O; Calmels, T; Ligneau, X; Berrebi-Bertrand, I; Robert, P; Lecomte, JM; Schwartz, JC; Capet, M Bioprojet-Biotech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50352090 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50352090&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 11977494 136358776 CHEMBL1824241 ZINC34774969 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 50925601 Clc1ccc(CCCOCCCN2CCCCC2)cc1 InChI=1S/C17H26ClNO/c18-17-9-7-16(8-10-17)6-4-14-20-15-5-13-19-11-2-1-3-12-19/h7-10H,1-6,11-15H2 NNACHAUCXXVJSP-UHFFFAOYSA-N 50247053 1-(3-(3-(4-chlorophenyl)propoxy)propyl)piperidine::CHEMBL462605::Tiprolisant Histamine H3 receptor Mus musculus 14 ChEMBL 10.1016/j.bmc.2018.04.023 10.7270/Q2TQ641P 29681486 Łażewska, D; Kaleta, M; Hagenow, S; Mogilski, S; Latacz, G; Karcz, T; Lubelska, A; Honkisz, E; Handzlik, J; Reiner, D; Satała, G; Filipek, B; Stark, H; Kieć-Kononowicz, K Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50247053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50247053&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 9948102 104102226 CHEMBL462605 ZINC34045468 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 51257948 O.OC(=O)\C=C\C(O)=O.CCCNC1CN(C1)c1ccnc(N)n1 InChI=1S/C10H17N5.C4H4O4.H2O/c1-2-4-12-8-6-15(7-8)9-3-5-13-10(11)14-9;5-3(6)1-2-4(7)8;/h3,5,8,12H,2,4,6-7H2,1H3,(H2,11,13,14);1-2H,(H,5,6)(H,7,8);1H2/b;2-1+; UZVUVIRYRBXPBX-JITBQSAISA-N 50514105 CHEMBL4441731 Histamine H3 receptor Mus musculus 0.100000 ChEMBL 10.1021/acs.jmedchem.9b01462 10.7270/Q2M61PKJ 31675226 Wágner, G; Mocking, TAM; Arimont, M; Provensi, G; Rani, B; Silva-Marques, B; Latacz, G; Da Costa Pereira, D; Karatzidou, C; Vischer, HF; Wijtmans, M; Kieć-Kononowicz, K; de Esch, IJP; Leurs, R Vrije Universiteit Amsterdam http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514105 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514105&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 155515478 440722687 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406 51257961 O.OC(=O)\C=C\C(O)=O.CCCNC1CN(C1)c1ccnc(N)n1 InChI=1S/C10H17N5.C4H4O4.H2O/c1-2-4-12-8-6-15(7-8)9-3-5-13-10(11)14-9;5-3(6)1-2-4(7)8;/h3,5,8,12H,2,4,6-7H2,1H3,(H2,11,13,14);1-2H,(H,5,6)(H,7,8);1H2/b;2-1+; UZVUVIRYRBXPBX-JITBQSAISA-N 50514105 CHEMBL4441731 Histamine H3 receptor Mus musculus 1.000000 ChEMBL 10.1021/acs.jmedchem.9b01462 10.7270/Q2M61PKJ 31675226 Wágner, G; Mocking, TAM; Arimont, M; Provensi, G; Rani, B; Silva-Marques, B; Latacz, G; Da Costa Pereira, D; Karatzidou, C; Vischer, HF; Wijtmans, M; Kieć-Kononowicz, K; de Esch, IJP; Leurs, R Vrije Universiteit Amsterdam http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514105 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50001382&target=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514105&enzyme=Histamine+H3+receptor&column=ki&startPg=0&Increment=50&submit=Search 155515478 440722687 1 MERAPPDGLMNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVETGEAGLGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK Histamine H3 receptor HRH3_MOUSE P58406