BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 51306932 C\C=C\c1nc(N)c2ncn([C@@H]3O[C@H](COS(=O)(=O)NC(=O)[C@@H](N)CO)[C@@H](O)[C@H]3O)c2n1 InChI=1S/C16H23N7O8S/c1-2-3-9-20-13(18)10-14(21-9)23(6-19-10)16-12(26)11(25)8(31-16)5-30-32(28,29)22-15(27)7(17)4-24/h2-3,6-8,11-12,16,24-26H,4-5,17H2,1H3,(H,22,27)(H2,18,20,21)/b3-2+/t7-,8+,11+,12+,16+/m0/s1 LARUACVXTYJANN-NMBVCXRMSA-N 50530861 CHEMBL4452350 Serine--tRNA ligase 3460 ChEMBL 10.1021/acs.jmedchem.9b01131 10.7270/Q2GX4G11 31626547 Cain, R; Salimraj, R; Punekar, AS; Bellini, D; Fishwick, CWG; Czaplewski, L; Scott, DJ; Harris, G; Dowson, CG; Lloyd, AJ; Roper, DI University of Warwick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50530861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000740&target=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50530861&enzyme=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search 155523347 440739443 1 MLDIRLFRNEPDTVKSKIELRGDDPKVVDEILELDEQRRKLISATEEMKARRNKVSEEIALKKRNKENADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILCRIPNLISDDVPQGESDEDNVEVKKWGTPREFSFEPKAHWDIVEELKMADFDRAAKVSGARFVYLTNEGAQLERALMNYMITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFYRNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLIRLHQFDKVEMVRFEQPEDSWNALEEMTTNAEAILEELGLPYRRVILCTGDIGFSASKTYDLEVWLPSYNDYKEISSCSNCTDFQARRANIRFKRDKAAKPELAHTLNGSGLAVGRTFAAIVENYQNEDGTVTIPEALVPFMGGKTQISKPVK 6R1N Serine--tRNA ligase SYS_STAA8 P95689 Q2G2P9 51306934 N[C@@H](CO)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(nc12)-c1ccccc1 InChI=1S/C19H23N7O8S/c20-10(6-27)18(30)25-35(31,32)33-7-11-13(28)14(29)19(34-11)26-8-22-12-15(21)23-16(24-17(12)26)9-4-2-1-3-5-9/h1-5,8,10-11,13-14,19,27-29H,6-7,20H2,(H,25,30)(H2,21,23,24)/t10-,11+,13+,14+,19+/m0/s1 VNBZTBMYEVMUKC-IFHUHSRSSA-N 50530860 CHEMBL4461782 Serine--tRNA ligase 52700 ChEMBL 10.1021/acs.jmedchem.9b01131 10.7270/Q2GX4G11 31626547 Cain, R; Salimraj, R; Punekar, AS; Bellini, D; Fishwick, CWG; Czaplewski, L; Scott, DJ; Harris, G; Dowson, CG; Lloyd, AJ; Roper, DI University of Warwick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50530860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000740&target=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50530860&enzyme=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search 155528796 440739442 1 MLDIRLFRNEPDTVKSKIELRGDDPKVVDEILELDEQRRKLISATEEMKARRNKVSEEIALKKRNKENADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILCRIPNLISDDVPQGESDEDNVEVKKWGTPREFSFEPKAHWDIVEELKMADFDRAAKVSGARFVYLTNEGAQLERALMNYMITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFYRNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLIRLHQFDKVEMVRFEQPEDSWNALEEMTTNAEAILEELGLPYRRVILCTGDIGFSASKTYDLEVWLPSYNDYKEISSCSNCTDFQARRANIRFKRDKAAKPELAHTLNGSGLAVGRTFAAIVENYQNEDGTVTIPEALVPFMGGKTQISKPVK 6R1N Serine--tRNA ligase SYS_STAA8 P95689 Q2G2P9 51306939 N[C@@H](CO)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 InChI=1S/C13H19N7O8S/c14-5(1-21)12(24)19-29(25,26)27-2-6-8(22)9(23)13(28-6)20-4-18-7-10(15)16-3-17-11(7)20/h3-6,8-9,13,21-23H,1-2,14H2,(H,19,24)(H2,15,16,17)/t5-,6+,8+,9+,13+/m0/s1 HQXFJGONGJPTLZ-YTMOPEAISA-N 50339906 ((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl(S)-2-amino-3-hydroxypropanoylsulfamate::5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE::CHEMBL1163070::SerSA Serine--tRNA ligase 230 ChEMBL 10.1021/acs.jmedchem.9b01131 10.7270/Q2GX4G11 31626547 Cain, R; Salimraj, R; Punekar, AS; Bellini, D; Fishwick, CWG; Czaplewski, L; Scott, DJ; Harris, G; Dowson, CG; Lloyd, AJ; Roper, DI University of Warwick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339906 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000740&target=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339906&enzyme=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search SSA 4L87,1FYF,6X94,3QO8,3W3S,2HL2,2CJ9,6R1N,6R1M,3HXW,1SET,3HY1,7U2B,7U2A,4EO4,6OTE,6H9X,2DQ0,2DQ3,7TZB,1TKG 445736 131342842 CHEMBL1163070 ZINC13542770 1 MLDIRLFRNEPDTVKSKIELRGDDPKVVDEILELDEQRRKLISATEEMKARRNKVSEEIALKKRNKENADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILCRIPNLISDDVPQGESDEDNVEVKKWGTPREFSFEPKAHWDIVEELKMADFDRAAKVSGARFVYLTNEGAQLERALMNYMITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFYRNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLIRLHQFDKVEMVRFEQPEDSWNALEEMTTNAEAILEELGLPYRRVILCTGDIGFSASKTYDLEVWLPSYNDYKEISSCSNCTDFQARRANIRFKRDKAAKPELAHTLNGSGLAVGRTFAAIVENYQNEDGTVTIPEALVPFMGGKTQISKPVK 6R1N Serine--tRNA ligase SYS_STAA8 P95689 Q2G2P9 51306940 N[C@@H](CO)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(nc12)-c1ccco1 InChI=1S/C17H21N7O9S/c18-7(4-25)16(28)23-34(29,30)32-5-9-11(26)12(27)17(33-9)24-6-20-10-13(19)21-14(22-15(10)24)8-2-1-3-31-8/h1-3,6-7,9,11-12,17,25-27H,4-5,18H2,(H,23,28)(H2,19,21,22)/t7-,9+,11+,12+,17+/m0/s1 YGMKBICWYKKCLS-OVUSCWQTSA-N 50530863 CHEMBL4449289 Serine--tRNA ligase 32400 ChEMBL 10.1021/acs.jmedchem.9b01131 10.7270/Q2GX4G11 31626547 Cain, R; Salimraj, R; Punekar, AS; Bellini, D; Fishwick, CWG; Czaplewski, L; Scott, DJ; Harris, G; Dowson, CG; Lloyd, AJ; Roper, DI University of Warwick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50530863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000740&target=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50530863&enzyme=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search 155520866 440739445 1 MLDIRLFRNEPDTVKSKIELRGDDPKVVDEILELDEQRRKLISATEEMKARRNKVSEEIALKKRNKENADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILCRIPNLISDDVPQGESDEDNVEVKKWGTPREFSFEPKAHWDIVEELKMADFDRAAKVSGARFVYLTNEGAQLERALMNYMITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFYRNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLIRLHQFDKVEMVRFEQPEDSWNALEEMTTNAEAILEELGLPYRRVILCTGDIGFSASKTYDLEVWLPSYNDYKEISSCSNCTDFQARRANIRFKRDKAAKPELAHTLNGSGLAVGRTFAAIVENYQNEDGTVTIPEALVPFMGGKTQISKPVK 6R1N Serine--tRNA ligase SYS_STAA8 P95689 Q2G2P9 51306941 N[C@@H](CO)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(nc12)-c1ccsc1 InChI=1S/C17H21N7O8S2/c18-8(3-25)16(28)23-34(29,30)31-4-9-11(26)12(27)17(32-9)24-6-20-10-13(19)21-14(22-15(10)24)7-1-2-33-5-7/h1-2,5-6,8-9,11-12,17,25-27H,3-4,18H2,(H,23,28)(H2,19,21,22)/t8-,9+,11+,12+,17+/m0/s1 JTCJPWQFWRCCFL-RBNOTYSOSA-N 50530862 CHEMBL4446951 Serine--tRNA ligase 1240 ChEMBL 10.1021/acs.jmedchem.9b01131 10.7270/Q2GX4G11 31626547 Cain, R; Salimraj, R; Punekar, AS; Bellini, D; Fishwick, CWG; Czaplewski, L; Scott, DJ; Harris, G; Dowson, CG; Lloyd, AJ; Roper, DI University of Warwick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50530862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000740&target=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50530862&enzyme=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search 155518884 440739444 1 MLDIRLFRNEPDTVKSKIELRGDDPKVVDEILELDEQRRKLISATEEMKARRNKVSEEIALKKRNKENADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILCRIPNLISDDVPQGESDEDNVEVKKWGTPREFSFEPKAHWDIVEELKMADFDRAAKVSGARFVYLTNEGAQLERALMNYMITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFYRNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLIRLHQFDKVEMVRFEQPEDSWNALEEMTTNAEAILEELGLPYRRVILCTGDIGFSASKTYDLEVWLPSYNDYKEISSCSNCTDFQARRANIRFKRDKAAKPELAHTLNGSGLAVGRTFAAIVENYQNEDGTVTIPEALVPFMGGKTQISKPVK 6R1N Serine--tRNA ligase SYS_STAA8 P95689 Q2G2P9 51306942 N[C@@H](CO)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(nc12)-c1cccnc1 InChI=1S/C18H22N8O8S/c19-9(5-27)17(30)25-35(31,32)33-6-10-12(28)13(29)18(34-10)26-7-22-11-14(20)23-15(24-16(11)26)8-2-1-3-21-4-8/h1-4,7,9-10,12-13,18,27-29H,5-6,19H2,(H,25,30)(H2,20,23,24)/t9-,10+,12+,13+,18+/m0/s1 AJLUWRJYNKUFKX-OBXKABKQSA-N 50530859 CHEMBL4561900 Serine--tRNA ligase 6340 ChEMBL 10.1021/acs.jmedchem.9b01131 10.7270/Q2GX4G11 31626547 Cain, R; Salimraj, R; Punekar, AS; Bellini, D; Fishwick, CWG; Czaplewski, L; Scott, DJ; Harris, G; Dowson, CG; Lloyd, AJ; Roper, DI University of Warwick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50530859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000740&target=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50530859&enzyme=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search JPE 6R1O 145829192 440739441 1 MLDIRLFRNEPDTVKSKIELRGDDPKVVDEILELDEQRRKLISATEEMKARRNKVSEEIALKKRNKENADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILCRIPNLISDDVPQGESDEDNVEVKKWGTPREFSFEPKAHWDIVEELKMADFDRAAKVSGARFVYLTNEGAQLERALMNYMITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFYRNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLIRLHQFDKVEMVRFEQPEDSWNALEEMTTNAEAILEELGLPYRRVILCTGDIGFSASKTYDLEVWLPSYNDYKEISSCSNCTDFQARRANIRFKRDKAAKPELAHTLNGSGLAVGRTFAAIVENYQNEDGTVTIPEALVPFMGGKTQISKPVK 6R1N Serine--tRNA ligase SYS_STAA8 P95689 Q2G2P9 51306952 N[C@@H](CO)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(I)nc12 InChI=1S/C13H18IN7O8S/c14-13-18-9(16)6-10(19-13)21(3-17-6)12-8(24)7(23)5(29-12)2-28-30(26,27)20-11(25)4(15)1-22/h3-5,7-8,12,22-24H,1-2,15H2,(H,20,25)(H2,16,18,19)/t4-,5+,7+,8+,12+/m0/s1 DGNJFKKZVYPDMV-IZKXYQSCSA-N 50530864 CHEMBL4467050 Serine--tRNA ligase 380 ChEMBL 10.1021/acs.jmedchem.9b01131 10.7270/Q2GX4G11 31626547 Cain, R; Salimraj, R; Punekar, AS; Bellini, D; Fishwick, CWG; Czaplewski, L; Scott, DJ; Harris, G; Dowson, CG; Lloyd, AJ; Roper, DI University of Warwick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50530864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000740&target=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50530864&enzyme=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search 155531870 440739446 1 MLDIRLFRNEPDTVKSKIELRGDDPKVVDEILELDEQRRKLISATEEMKARRNKVSEEIALKKRNKENADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILCRIPNLISDDVPQGESDEDNVEVKKWGTPREFSFEPKAHWDIVEELKMADFDRAAKVSGARFVYLTNEGAQLERALMNYMITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFYRNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLIRLHQFDKVEMVRFEQPEDSWNALEEMTTNAEAILEELGLPYRRVILCTGDIGFSASKTYDLEVWLPSYNDYKEISSCSNCTDFQARRANIRFKRDKAAKPELAHTLNGSGLAVGRTFAAIVENYQNEDGTVTIPEALVPFMGGKTQISKPVK 6R1N Serine--tRNA ligase SYS_STAA8 P95689 Q2G2P9 51306959 N[C@@H](CO)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 InChI=1S/C13H19N7O8S/c14-5(1-21)12(24)19-29(25,26)27-2-6-8(22)9(23)13(28-6)20-4-18-7-10(15)16-3-17-11(7)20/h3-6,8-9,13,21-23H,1-2,14H2,(H,19,24)(H2,15,16,17)/t5-,6+,8+,9+,13+/m0/s1 HQXFJGONGJPTLZ-YTMOPEAISA-N 50339906 ((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl(S)-2-amino-3-hydroxypropanoylsulfamate::5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE::CHEMBL1163070::SerSA Serine--tRNA ligase 230 ChEMBL 10.1021/acs.jmedchem.9b01131 10.7270/Q2GX4G11 31626547 Cain, R; Salimraj, R; Punekar, AS; Bellini, D; Fishwick, CWG; Czaplewski, L; Scott, DJ; Harris, G; Dowson, CG; Lloyd, AJ; Roper, DI University of Warwick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339906 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000740&target=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339906&enzyme=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search SSA 4L87,1FYF,6X94,3QO8,3W3S,2HL2,2CJ9,6R1N,6R1M,3HXW,1SET,3HY1,7U2B,7U2A,4EO4,6OTE,6H9X,2DQ0,2DQ3,7TZB,1TKG 445736 131342842 CHEMBL1163070 ZINC13542770 1 MLDIRLFRNEPDTVKSKIELRGDDPKVVDEILELDEQRRKLISATEEMKARRNKVSEEIALKKRNKENADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILCRIPNLISDDVPQGESDEDNVEVKKWGTPREFSFEPKAHWDIVEELKMADFDRAAKVSGARFVYLTNEGAQLERALMNYMITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFYRNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLIRLHQFDKVEMVRFEQPEDSWNALEEMTTNAEAILEELGLPYRRVILCTGDIGFSASKTYDLEVWLPSYNDYKEISSCSNCTDFQARRANIRFKRDKAAKPELAHTLNGSGLAVGRTFAAIVENYQNEDGTVTIPEALVPFMGGKTQISKPVK 6R1N Serine--tRNA ligase SYS_STAA8 P95689 Q2G2P9 51306960 N[C@@H](CO)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(I)nc12 InChI=1S/C13H18IN7O8S/c14-13-18-9(16)6-10(19-13)21(3-17-6)12-8(24)7(23)5(29-12)2-28-30(26,27)20-11(25)4(15)1-22/h3-5,7-8,12,22-24H,1-2,15H2,(H,20,25)(H2,16,18,19)/t4-,5+,7+,8+,12+/m0/s1 DGNJFKKZVYPDMV-IZKXYQSCSA-N 50530864 CHEMBL4467050 Serine--tRNA ligase 380 ChEMBL 10.1021/acs.jmedchem.9b01131 10.7270/Q2GX4G11 31626547 Cain, R; Salimraj, R; Punekar, AS; Bellini, D; Fishwick, CWG; Czaplewski, L; Scott, DJ; Harris, G; Dowson, CG; Lloyd, AJ; Roper, DI University of Warwick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50530864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000740&target=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50530864&enzyme=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search 155531870 440739446 1 MLDIRLFRNEPDTVKSKIELRGDDPKVVDEILELDEQRRKLISATEEMKARRNKVSEEIALKKRNKENADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILCRIPNLISDDVPQGESDEDNVEVKKWGTPREFSFEPKAHWDIVEELKMADFDRAAKVSGARFVYLTNEGAQLERALMNYMITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFYRNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLIRLHQFDKVEMVRFEQPEDSWNALEEMTTNAEAILEELGLPYRRVILCTGDIGFSASKTYDLEVWLPSYNDYKEISSCSNCTDFQARRANIRFKRDKAAKPELAHTLNGSGLAVGRTFAAIVENYQNEDGTVTIPEALVPFMGGKTQISKPVK 6R1N Serine--tRNA ligase SYS_STAA8 P95689 Q2G2P9 51306961 N[C@@H](CO)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(nc12)-c1ccco1 InChI=1S/C17H21N7O9S/c18-7(4-25)16(28)23-34(29,30)32-5-9-11(26)12(27)17(33-9)24-6-20-10-13(19)21-14(22-15(10)24)8-2-1-3-31-8/h1-3,6-7,9,11-12,17,25-27H,4-5,18H2,(H,23,28)(H2,19,21,22)/t7-,9+,11+,12+,17+/m0/s1 YGMKBICWYKKCLS-OVUSCWQTSA-N 50530863 CHEMBL4449289 Serine--tRNA ligase 32400 ChEMBL 10.1021/acs.jmedchem.9b01131 10.7270/Q2GX4G11 31626547 Cain, R; Salimraj, R; Punekar, AS; Bellini, D; Fishwick, CWG; Czaplewski, L; Scott, DJ; Harris, G; Dowson, CG; Lloyd, AJ; Roper, DI University of Warwick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50530863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000740&target=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50530863&enzyme=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search 155520866 440739445 1 MLDIRLFRNEPDTVKSKIELRGDDPKVVDEILELDEQRRKLISATEEMKARRNKVSEEIALKKRNKENADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILCRIPNLISDDVPQGESDEDNVEVKKWGTPREFSFEPKAHWDIVEELKMADFDRAAKVSGARFVYLTNEGAQLERALMNYMITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFYRNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLIRLHQFDKVEMVRFEQPEDSWNALEEMTTNAEAILEELGLPYRRVILCTGDIGFSASKTYDLEVWLPSYNDYKEISSCSNCTDFQARRANIRFKRDKAAKPELAHTLNGSGLAVGRTFAAIVENYQNEDGTVTIPEALVPFMGGKTQISKPVK 6R1N Serine--tRNA ligase SYS_STAA8 P95689 Q2G2P9 51306962 N[C@@H](CO)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(nc12)-c1ccsc1 InChI=1S/C17H21N7O8S2/c18-8(3-25)16(28)23-34(29,30)31-4-9-11(26)12(27)17(32-9)24-6-20-10-13(19)21-14(22-15(10)24)7-1-2-33-5-7/h1-2,5-6,8-9,11-12,17,25-27H,3-4,18H2,(H,23,28)(H2,19,21,22)/t8-,9+,11+,12+,17+/m0/s1 JTCJPWQFWRCCFL-RBNOTYSOSA-N 50530862 CHEMBL4446951 Serine--tRNA ligase 1240 ChEMBL 10.1021/acs.jmedchem.9b01131 10.7270/Q2GX4G11 31626547 Cain, R; Salimraj, R; Punekar, AS; Bellini, D; Fishwick, CWG; Czaplewski, L; Scott, DJ; Harris, G; Dowson, CG; Lloyd, AJ; Roper, DI University of Warwick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50530862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000740&target=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50530862&enzyme=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search 155518884 440739444 1 MLDIRLFRNEPDTVKSKIELRGDDPKVVDEILELDEQRRKLISATEEMKARRNKVSEEIALKKRNKENADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILCRIPNLISDDVPQGESDEDNVEVKKWGTPREFSFEPKAHWDIVEELKMADFDRAAKVSGARFVYLTNEGAQLERALMNYMITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFYRNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLIRLHQFDKVEMVRFEQPEDSWNALEEMTTNAEAILEELGLPYRRVILCTGDIGFSASKTYDLEVWLPSYNDYKEISSCSNCTDFQARRANIRFKRDKAAKPELAHTLNGSGLAVGRTFAAIVENYQNEDGTVTIPEALVPFMGGKTQISKPVK 6R1N Serine--tRNA ligase SYS_STAA8 P95689 Q2G2P9 51306963 N[C@@H](CO)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(nc12)-c1cccnc1 InChI=1S/C18H22N8O8S/c19-9(5-27)17(30)25-35(31,32)33-6-10-12(28)13(29)18(34-10)26-7-22-11-14(20)23-15(24-16(11)26)8-2-1-3-21-4-8/h1-4,7,9-10,12-13,18,27-29H,5-6,19H2,(H,25,30)(H2,20,23,24)/t9-,10+,12+,13+,18+/m0/s1 AJLUWRJYNKUFKX-OBXKABKQSA-N 50530859 CHEMBL4561900 Serine--tRNA ligase 6340 ChEMBL 10.1021/acs.jmedchem.9b01131 10.7270/Q2GX4G11 31626547 Cain, R; Salimraj, R; Punekar, AS; Bellini, D; Fishwick, CWG; Czaplewski, L; Scott, DJ; Harris, G; Dowson, CG; Lloyd, AJ; Roper, DI University of Warwick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50530859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000740&target=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50530859&enzyme=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search JPE 6R1O 145829192 440739441 1 MLDIRLFRNEPDTVKSKIELRGDDPKVVDEILELDEQRRKLISATEEMKARRNKVSEEIALKKRNKENADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILCRIPNLISDDVPQGESDEDNVEVKKWGTPREFSFEPKAHWDIVEELKMADFDRAAKVSGARFVYLTNEGAQLERALMNYMITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFYRNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLIRLHQFDKVEMVRFEQPEDSWNALEEMTTNAEAILEELGLPYRRVILCTGDIGFSASKTYDLEVWLPSYNDYKEISSCSNCTDFQARRANIRFKRDKAAKPELAHTLNGSGLAVGRTFAAIVENYQNEDGTVTIPEALVPFMGGKTQISKPVK 6R1N Serine--tRNA ligase SYS_STAA8 P95689 Q2G2P9 51306968 CC1(C)O[C@@H]2[C@@H](CO)O[C@H]([C@@H]2O1)n1cnc2c(N)nc(I)nc12 InChI=1S/C13H16IN5O4/c1-13(2)22-7-5(3-20)21-11(8(7)23-13)19-4-16-6-9(15)17-12(14)18-10(6)19/h4-5,7-8,11,20H,3H2,1-2H3,(H2,15,17,18)/t5-,7-,8-,11-/m1/s1 KNWSBURSUIDKHK-IOSLPCCCSA-N 50530865 CHEMBL4471342 Serine--tRNA ligase 231000 ChEMBL 10.1021/acs.jmedchem.9b01131 10.7270/Q2GX4G11 31626547 Cain, R; Salimraj, R; Punekar, AS; Bellini, D; Fishwick, CWG; Czaplewski, L; Scott, DJ; Harris, G; Dowson, CG; Lloyd, AJ; Roper, DI University of Warwick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50530865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000740&target=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50530865&enzyme=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search 14999717 440739447 1 MLDIRLFRNEPDTVKSKIELRGDDPKVVDEILELDEQRRKLISATEEMKARRNKVSEEIALKKRNKENADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILCRIPNLISDDVPQGESDEDNVEVKKWGTPREFSFEPKAHWDIVEELKMADFDRAAKVSGARFVYLTNEGAQLERALMNYMITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFYRNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLIRLHQFDKVEMVRFEQPEDSWNALEEMTTNAEAILEELGLPYRRVILCTGDIGFSASKTYDLEVWLPSYNDYKEISSCSNCTDFQARRANIRFKRDKAAKPELAHTLNGSGLAVGRTFAAIVENYQNEDGTVTIPEALVPFMGGKTQISKPVK 6R1N Serine--tRNA ligase SYS_STAA8 P95689 Q2G2P9 51306970 N[C@@H](CO)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(Cl)nc12 InChI=1S/C13H18ClN7O8S/c14-13-18-9(16)6-10(19-13)21(3-17-6)12-8(24)7(23)5(29-12)2-28-30(26,27)20-11(25)4(15)1-22/h3-5,7-8,12,22-24H,1-2,15H2,(H,20,25)(H2,16,18,19)/t4-,5+,7+,8+,12+/m0/s1 WTBVOEZPQDNBKG-IZKXYQSCSA-N 50530866 CHEMBL4529844 Serine--tRNA ligase 260 ChEMBL 10.1021/acs.jmedchem.9b01131 10.7270/Q2GX4G11 31626547 Cain, R; Salimraj, R; Punekar, AS; Bellini, D; Fishwick, CWG; Czaplewski, L; Scott, DJ; Harris, G; Dowson, CG; Lloyd, AJ; Roper, DI University of Warwick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50530866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000740&target=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50530866&enzyme=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search 155545731 440739448 1 MLDIRLFRNEPDTVKSKIELRGDDPKVVDEILELDEQRRKLISATEEMKARRNKVSEEIALKKRNKENADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILCRIPNLISDDVPQGESDEDNVEVKKWGTPREFSFEPKAHWDIVEELKMADFDRAAKVSGARFVYLTNEGAQLERALMNYMITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFYRNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLIRLHQFDKVEMVRFEQPEDSWNALEEMTTNAEAILEELGLPYRRVILCTGDIGFSASKTYDLEVWLPSYNDYKEISSCSNCTDFQARRANIRFKRDKAAKPELAHTLNGSGLAVGRTFAAIVENYQNEDGTVTIPEALVPFMGGKTQISKPVK 6R1N Serine--tRNA ligase SYS_STAA8 P95689 Q2G2P9 51306974 C\C=C\c1nc(N)c2ncn([C@@H]3O[C@H](COS(=O)(=O)NC(=O)[C@@H](N)CO)[C@@H](O)[C@H]3O)c2n1 InChI=1S/C16H23N7O8S/c1-2-3-9-20-13(18)10-14(21-9)23(6-19-10)16-12(26)11(25)8(31-16)5-30-32(28,29)22-15(27)7(17)4-24/h2-3,6-8,11-12,16,24-26H,4-5,17H2,1H3,(H,22,27)(H2,18,20,21)/b3-2+/t7-,8+,11+,12+,16+/m0/s1 LARUACVXTYJANN-NMBVCXRMSA-N 50530861 CHEMBL4452350 Serine--tRNA ligase 3460 ChEMBL 10.1021/acs.jmedchem.9b01131 10.7270/Q2GX4G11 31626547 Cain, R; Salimraj, R; Punekar, AS; Bellini, D; Fishwick, CWG; Czaplewski, L; Scott, DJ; Harris, G; Dowson, CG; Lloyd, AJ; Roper, DI University of Warwick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50530861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000740&target=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50530861&enzyme=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search 155523347 440739443 1 MLDIRLFRNEPDTVKSKIELRGDDPKVVDEILELDEQRRKLISATEEMKARRNKVSEEIALKKRNKENADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILCRIPNLISDDVPQGESDEDNVEVKKWGTPREFSFEPKAHWDIVEELKMADFDRAAKVSGARFVYLTNEGAQLERALMNYMITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFYRNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLIRLHQFDKVEMVRFEQPEDSWNALEEMTTNAEAILEELGLPYRRVILCTGDIGFSASKTYDLEVWLPSYNDYKEISSCSNCTDFQARRANIRFKRDKAAKPELAHTLNGSGLAVGRTFAAIVENYQNEDGTVTIPEALVPFMGGKTQISKPVK 6R1N Serine--tRNA ligase SYS_STAA8 P95689 Q2G2P9 51306977 CC1(C)O[C@@H]2[C@@H](CO)O[C@H]([C@@H]2O1)n1cnc2c(N)nc(I)nc12 InChI=1S/C13H16IN5O4/c1-13(2)22-7-5(3-20)21-11(8(7)23-13)19-4-16-6-9(15)17-12(14)18-10(6)19/h4-5,7-8,11,20H,3H2,1-2H3,(H2,15,17,18)/t5-,7-,8-,11-/m1/s1 KNWSBURSUIDKHK-IOSLPCCCSA-N 50530865 CHEMBL4471342 Serine--tRNA ligase 231000 ChEMBL 10.1021/acs.jmedchem.9b01131 10.7270/Q2GX4G11 31626547 Cain, R; Salimraj, R; Punekar, AS; Bellini, D; Fishwick, CWG; Czaplewski, L; Scott, DJ; Harris, G; Dowson, CG; Lloyd, AJ; Roper, DI University of Warwick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50530865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000740&target=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50530865&enzyme=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search 14999717 440739447 1 MLDIRLFRNEPDTVKSKIELRGDDPKVVDEILELDEQRRKLISATEEMKARRNKVSEEIALKKRNKENADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILCRIPNLISDDVPQGESDEDNVEVKKWGTPREFSFEPKAHWDIVEELKMADFDRAAKVSGARFVYLTNEGAQLERALMNYMITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFYRNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLIRLHQFDKVEMVRFEQPEDSWNALEEMTTNAEAILEELGLPYRRVILCTGDIGFSASKTYDLEVWLPSYNDYKEISSCSNCTDFQARRANIRFKRDKAAKPELAHTLNGSGLAVGRTFAAIVENYQNEDGTVTIPEALVPFMGGKTQISKPVK 6R1N Serine--tRNA ligase SYS_STAA8 P95689 Q2G2P9 51306980 N[C@@H](CO)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(Cl)nc12 InChI=1S/C13H18ClN7O8S/c14-13-18-9(16)6-10(19-13)21(3-17-6)12-8(24)7(23)5(29-12)2-28-30(26,27)20-11(25)4(15)1-22/h3-5,7-8,12,22-24H,1-2,15H2,(H,20,25)(H2,16,18,19)/t4-,5+,7+,8+,12+/m0/s1 WTBVOEZPQDNBKG-IZKXYQSCSA-N 50530866 CHEMBL4529844 Serine--tRNA ligase 260 ChEMBL 10.1021/acs.jmedchem.9b01131 10.7270/Q2GX4G11 31626547 Cain, R; Salimraj, R; Punekar, AS; Bellini, D; Fishwick, CWG; Czaplewski, L; Scott, DJ; Harris, G; Dowson, CG; Lloyd, AJ; Roper, DI University of Warwick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50530866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000740&target=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50530866&enzyme=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search 155545731 440739448 1 MLDIRLFRNEPDTVKSKIELRGDDPKVVDEILELDEQRRKLISATEEMKARRNKVSEEIALKKRNKENADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILCRIPNLISDDVPQGESDEDNVEVKKWGTPREFSFEPKAHWDIVEELKMADFDRAAKVSGARFVYLTNEGAQLERALMNYMITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFYRNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLIRLHQFDKVEMVRFEQPEDSWNALEEMTTNAEAILEELGLPYRRVILCTGDIGFSASKTYDLEVWLPSYNDYKEISSCSNCTDFQARRANIRFKRDKAAKPELAHTLNGSGLAVGRTFAAIVENYQNEDGTVTIPEALVPFMGGKTQISKPVK 6R1N Serine--tRNA ligase SYS_STAA8 P95689 Q2G2P9 51306986 N[C@@H](CO)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(nc12)-c1ccccc1 InChI=1S/C19H23N7O8S/c20-10(6-27)18(30)25-35(31,32)33-7-11-13(28)14(29)19(34-11)26-8-22-12-15(21)23-16(24-17(12)26)9-4-2-1-3-5-9/h1-5,8,10-11,13-14,19,27-29H,6-7,20H2,(H,25,30)(H2,21,23,24)/t10-,11+,13+,14+,19+/m0/s1 VNBZTBMYEVMUKC-IFHUHSRSSA-N 50530860 CHEMBL4461782 Serine--tRNA ligase 52700 ChEMBL 10.1021/acs.jmedchem.9b01131 10.7270/Q2GX4G11 31626547 Cain, R; Salimraj, R; Punekar, AS; Bellini, D; Fishwick, CWG; Czaplewski, L; Scott, DJ; Harris, G; Dowson, CG; Lloyd, AJ; Roper, DI University of Warwick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50530860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000740&target=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50530860&enzyme=Serine--tRNA+ligase&column=ki&startPg=0&Increment=50&submit=Search 155528796 440739442 1 MLDIRLFRNEPDTVKSKIELRGDDPKVVDEILELDEQRRKLISATEEMKARRNKVSEEIALKKRNKENADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILCRIPNLISDDVPQGESDEDNVEVKKWGTPREFSFEPKAHWDIVEELKMADFDRAAKVSGARFVYLTNEGAQLERALMNYMITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFYRNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLIRLHQFDKVEMVRFEQPEDSWNALEEMTTNAEAILEELGLPYRRVILCTGDIGFSASKTYDLEVWLPSYNDYKEISSCSNCTDFQARRANIRFKRDKAAKPELAHTLNGSGLAVGRTFAAIVENYQNEDGTVTIPEALVPFMGGKTQISKPVK 6R1N Serine--tRNA ligase SYS_STAA8 P95689 Q2G2P9