BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 50093825 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cc\c(=N\OCCCC(O)=O)[nH]c1=O InChI=1S/C13H22N3O17P3/c17-9(18)2-1-5-29-15-8-3-4-16(13(21)14-8)12-11(20)10(19)7(31-12)6-30-35(25,26)33-36(27,28)32-34(22,23)24/h3-4,7,10-12,19-20H,1-2,5-6H2,(H,17,18)(H,25,26)(H,27,28)(H,14,15,21)(H2,22,23,24)/t7-,10-,11-,12-/m1/s1 RFTFMAKDHFXRTP-FAQVLOEFSA-N 50012953 CHEMBL3261359 P2Y purinoceptor 4 Homo sapiens 470 ChEMBL 10.1021/jm500367e 10.7270/Q2V989M9 24712832 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Hammes, E; Balasubramanian, R; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012953 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012953&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 90656210 103925203 CHEMBL3261359 C03517 ZINC03919333 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50093826 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cc\c(=N\OCCCCc2ccccc2)[nH]c1=O InChI=1S/C19H28N3O15P3/c23-16-14(12-34-39(29,30)37-40(31,32)36-38(26,27)28)35-18(17(16)24)22-10-9-15(20-19(22)25)21-33-11-5-4-8-13-6-2-1-3-7-13/h1-3,6-7,9-10,14,16-18,23-24H,4-5,8,11-12H2,(H,29,30)(H,31,32)(H,20,21,25)(H2,26,27,28)/t14-,16-,17-,18-/m1/s1 YIIHWWZMFGDXDI-VDHUWJSZSA-N 50012954 CHEMBL3261360 P2Y purinoceptor 4 Homo sapiens 54 ChEMBL 10.1021/jm500367e 10.7270/Q2V989M9 24712832 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Hammes, E; Balasubramanian, R; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012954&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 90656211 242058164 CHEMBL3261360 C03517 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50093827 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cc\c(=N\OCCOc2ccccc2)[nH]c1=O InChI=1S/C17H24N3O16P3/c21-14-12(10-33-38(27,28)36-39(29,30)35-37(24,25)26)34-16(15(14)22)20-7-6-13(18-17(20)23)19-32-9-8-31-11-4-2-1-3-5-11/h1-7,12,14-16,21-22H,8-10H2,(H,27,28)(H,29,30)(H,18,19,23)(H2,24,25,26)/t12-,14-,15-,16-/m1/s1 AXEDFADFROXMCZ-DTZQCDIJSA-N 50012955 CHEMBL3261361 P2Y purinoceptor 4 Homo sapiens 430 ChEMBL 10.1021/jm500367e 10.7270/Q2V989M9 24712832 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Hammes, E; Balasubramanian, R; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012955&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 90656212 242058165 CHEMBL3261361 C03517 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50093828 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cc\c(=N\OCCCc2cccc(F)c2)[nH]c1=O InChI=1S/C18H25FN3O15P3/c19-12-5-1-3-11(9-12)4-2-8-33-21-14-6-7-22(18(25)20-14)17-16(24)15(23)13(35-17)10-34-39(29,30)37-40(31,32)36-38(26,27)28/h1,3,5-7,9,13,15-17,23-24H,2,4,8,10H2,(H,29,30)(H,31,32)(H,20,21,25)(H2,26,27,28)/t13-,15-,16-,17-/m1/s1 IVCDMZNEXSTYPU-MWQQHZPXSA-N 50012958 CHEMBL3261362 P2Y purinoceptor 4 Homo sapiens 100 ChEMBL 10.1021/jm500367e 10.7270/Q2V989M9 24712832 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Hammes, E; Balasubramanian, R; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012958&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 90656213 103925206 CHEMBL3261362 C03517 ZINC26845790 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50093829 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cc\c(=N\OCCCc2ccc(F)cc2)[nH]c1=O InChI=1S/C18H25FN3O15P3/c19-12-5-3-11(4-6-12)2-1-9-33-21-14-7-8-22(18(25)20-14)17-16(24)15(23)13(35-17)10-34-39(29,30)37-40(31,32)36-38(26,27)28/h3-8,13,15-17,23-24H,1-2,9-10H2,(H,29,30)(H,31,32)(H,20,21,25)(H2,26,27,28)/t13-,15-,16-,17-/m1/s1 CHNFEKRMOKHRTP-MWQQHZPXSA-N 50012972 CHEMBL3261363 P2Y purinoceptor 4 Homo sapiens 105 ChEMBL 10.1021/jm500367e 10.7270/Q2V989M9 24712832 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Hammes, E; Balasubramanian, R; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012972 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012972&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 90656214 242058166 CHEMBL3261363 C03517 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50093830 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cc\c(=N\OCCCc2ccc(Br)cc2)[nH]c1=O InChI=1S/C18H25BrN3O15P3/c19-12-5-3-11(4-6-12)2-1-9-33-21-14-7-8-22(18(25)20-14)17-16(24)15(23)13(35-17)10-34-39(29,30)37-40(31,32)36-38(26,27)28/h3-8,13,15-17,23-24H,1-2,9-10H2,(H,29,30)(H,31,32)(H,20,21,25)(H2,26,27,28)/t13-,15-,16-,17-/m1/s1 ZZVKCNXEXXPUFN-MWQQHZPXSA-N 50012973 CHEMBL3261364 P2Y purinoceptor 4 Homo sapiens 141 ChEMBL 10.1021/jm500367e 10.7270/Q2V989M9 24712832 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Hammes, E; Balasubramanian, R; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012973 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012973&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 90656215 242058167 CHEMBL3261364 C03517 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50093834 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cc\c(=N\OCCCc2cccc(I)c2)[nH]c1=O InChI=1S/C18H25IN3O15P3/c19-12-5-1-3-11(9-12)4-2-8-33-21-14-6-7-22(18(25)20-14)17-16(24)15(23)13(35-17)10-34-39(29,30)37-40(31,32)36-38(26,27)28/h1,3,5-7,9,13,15-17,23-24H,2,4,8,10H2,(H,29,30)(H,31,32)(H,20,21,25)(H2,26,27,28)/t13-,15-,16-,17-/m1/s1 BSXYCTKWYPJKSC-MWQQHZPXSA-N 50012974 CHEMBL3261365 P2Y purinoceptor 4 Homo sapiens 114 ChEMBL 10.1021/jm500367e 10.7270/Q2V989M9 24712832 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Hammes, E; Balasubramanian, R; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012974&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 90656216 242058168 CHEMBL3261365 C03517 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50093835 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cc\c(=N\OCCCc2ccc(I)cc2)[nH]c1=O InChI=1S/C18H25IN3O15P3/c19-12-5-3-11(4-6-12)2-1-9-33-21-14-7-8-22(18(25)20-14)17-16(24)15(23)13(35-17)10-34-39(29,30)37-40(31,32)36-38(26,27)28/h3-8,13,15-17,23-24H,1-2,9-10H2,(H,29,30)(H,31,32)(H,20,21,25)(H2,26,27,28)/t13-,15-,16-,17-/m1/s1 XUECUURNOIRWRO-MWQQHZPXSA-N 50012975 CHEMBL3261366 P2Y purinoceptor 4 Homo sapiens 91 ChEMBL 10.1021/jm500367e 10.7270/Q2V989M9 24712832 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Hammes, E; Balasubramanian, R; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012975&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 90656217 242058169 CHEMBL3261366 C03517 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50093836 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cc\c(=N\OCCCc2cccc(c2)[N+]([O-])=O)[nH]c1=O InChI=1S/C18H25N4O17P3/c23-15-13(10-36-41(31,32)39-42(33,34)38-40(28,29)30)37-17(16(15)24)21-7-6-14(19-18(21)25)20-35-8-2-4-11-3-1-5-12(9-11)22(26)27/h1,3,5-7,9,13,15-17,23-24H,2,4,8,10H2,(H,31,32)(H,33,34)(H,19,20,25)(H2,28,29,30)/t13-,15-,16-,17-/m1/s1 VRMSKJWDXHXVTC-MWQQHZPXSA-N 50012976 CHEMBL3261367 P2Y purinoceptor 4 Homo sapiens 95 ChEMBL 10.1021/jm500367e 10.7270/Q2V989M9 24712832 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Hammes, E; Balasubramanian, R; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012976 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012976&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 90656218 242058170 CHEMBL3261367 C03517 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50093837 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cc\c(=N\OCCCc2ccc(cc2)[N+]([O-])=O)[nH]c1=O InChI=1S/C18H25N4O17P3/c23-15-13(10-36-41(31,32)39-42(33,34)38-40(28,29)30)37-17(16(15)24)21-8-7-14(19-18(21)25)20-35-9-1-2-11-3-5-12(6-4-11)22(26)27/h3-8,13,15-17,23-24H,1-2,9-10H2,(H,31,32)(H,33,34)(H,19,20,25)(H2,28,29,30)/t13-,15-,16-,17-/m1/s1 FDWSSYHSADJRQV-MWQQHZPXSA-N 50012977 CHEMBL3261368 P2Y purinoceptor 4 Homo sapiens 84 ChEMBL 10.1021/jm500367e 10.7270/Q2V989M9 24712832 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Hammes, E; Balasubramanian, R; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012977 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012977&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 90656219 242058171 CHEMBL3261368 C03517 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50093839 COc1ccc(CCCO\N=c2\ccn([C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)c(=O)[nH]2)cc1 InChI=1S/C19H28N3O16P3/c1-33-13-6-4-12(5-7-13)3-2-10-34-21-15-8-9-22(19(25)20-15)18-17(24)16(23)14(36-18)11-35-40(29,30)38-41(31,32)37-39(26,27)28/h4-9,14,16-18,23-24H,2-3,10-11H2,1H3,(H,29,30)(H,31,32)(H,20,21,25)(H2,26,27,28)/t14-,16-,17-,18-/m1/s1 NIHFTZIOZPMEPG-VDHUWJSZSA-N 50012978 CHEMBL3261369 P2Y purinoceptor 4 Homo sapiens 23 ChEMBL 10.1021/jm500367e 10.7270/Q2V989M9 24712832 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Hammes, E; Balasubramanian, R; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012978&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 90656220 242058172 CHEMBL3261369 C03517 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50093841 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cc\c(=N\OCCCc2cccnc2)[nH]c1=O InChI=1S/C17H25N4O15P3/c22-14-12(10-33-38(28,29)36-39(30,31)35-37(25,26)27)34-16(15(14)23)21-7-5-13(19-17(21)24)20-32-8-2-4-11-3-1-6-18-9-11/h1,3,5-7,9,12,14-16,22-23H,2,4,8,10H2,(H,28,29)(H,30,31)(H,19,20,24)(H2,25,26,27)/t12-,14-,15-,16-/m1/s1 HSMPKTMBTKQCEP-DTZQCDIJSA-N 50012979 CHEMBL3261370 P2Y purinoceptor 4 Homo sapiens 300 ChEMBL 10.1021/jm500367e 10.7270/Q2V989M9 24712832 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Hammes, E; Balasubramanian, R; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012979 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012979&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 90656221 242058173 CHEMBL3261370 C03517 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50093842 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cc\c(=N\OCCCc2ccncc2)[nH]c1=O InChI=1S/C17H25N4O15P3/c22-14-12(10-33-38(28,29)36-39(30,31)35-37(25,26)27)34-16(15(14)23)21-8-5-13(19-17(21)24)20-32-9-1-2-11-3-6-18-7-4-11/h3-8,12,14-16,22-23H,1-2,9-10H2,(H,28,29)(H,30,31)(H,19,20,24)(H2,25,26,27)/t12-,14-,15-,16-/m1/s1 GDYLVBZFJDZQBP-DTZQCDIJSA-N 50013009 CHEMBL3261371 P2Y purinoceptor 4 Homo sapiens 250 ChEMBL 10.1021/jm500367e 10.7270/Q2V989M9 24712832 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Hammes, E; Balasubramanian, R; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013009 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013009&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 90656222 242058174 CHEMBL3261371 C03517 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50093843 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cc\c(=N\OCCCc2ccsc2)[nH]c1=O InChI=1S/C16H24N3O15P3S/c20-13-11(8-31-36(26,27)34-37(28,29)33-35(23,24)25)32-15(14(13)21)19-5-3-12(17-16(19)22)18-30-6-1-2-10-4-7-38-9-10/h3-5,7,9,11,13-15,20-21H,1-2,6,8H2,(H,26,27)(H,28,29)(H,17,18,22)(H2,23,24,25)/t11-,13-,14-,15-/m1/s1 SGLXVPVUSHCSPV-NMFUWQPSSA-N 50013010 CHEMBL3261372 P2Y purinoceptor 4 Homo sapiens 20 ChEMBL 10.1021/jm500367e 10.7270/Q2V989M9 24712832 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Hammes, E; Balasubramanian, R; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013010&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 90656223 242058175 CHEMBL3261372 C03517 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50093846 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cc\c(=N\OCCCC#C)[nH]c1=O InChI=1S/C14H22N3O15P3/c1-2-3-4-7-28-16-10-5-6-17(14(20)15-10)13-12(19)11(18)9(30-13)8-29-34(24,25)32-35(26,27)31-33(21,22)23/h1,5-6,9,11-13,18-19H,3-4,7-8H2,(H,24,25)(H,26,27)(H,15,16,20)(H2,21,22,23)/t9-,11-,12-,13-/m1/s1 CYLHTYSEZSCXEN-OJAKKHQRSA-N 50013011 CHEMBL3261373 P2Y purinoceptor 4 Homo sapiens 410 ChEMBL 10.1021/jm500367e 10.7270/Q2V989M9 24712832 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Hammes, E; Balasubramanian, R; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013011&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 90656224 242058176 CHEMBL3261373 C03517 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50093853 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cc\c(=N\OCCCc2ccc3ccccc3c2)[nH]c1=O InChI=1S/C22H28N3O15P3/c26-19-17(13-37-42(32,33)40-43(34,35)39-41(29,30)31)38-21(20(19)27)25-10-9-18(23-22(25)28)24-36-11-3-4-14-7-8-15-5-1-2-6-16(15)12-14/h1-2,5-10,12,17,19-21,26-27H,3-4,11,13H2,(H,32,33)(H,34,35)(H,23,24,28)(H2,29,30,31)/t17-,19-,20-,21-/m1/s1 MXBRGZVUXNVHNI-CWJKEVGVSA-N 50013012 CHEMBL3261374 P2Y purinoceptor 4 Homo sapiens 128 ChEMBL 10.1021/jm500367e 10.7270/Q2V989M9 24712832 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Hammes, E; Balasubramanian, R; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013012&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 90656225 242058177 CHEMBL3261374 C03517 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50093856 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cc\c(=N\OCCC(C#N)(c2ccccc2)c2ccccc2)[nH]c1=O InChI=1S/C25H29N4O15P3/c26-16-25(17-7-3-1-4-8-17,18-9-5-2-6-10-18)12-14-40-28-20-11-13-29(24(32)27-20)23-22(31)21(30)19(42-23)15-41-46(36,37)44-47(38,39)43-45(33,34)35/h1-11,13,19,21-23,30-31H,12,14-15H2,(H,36,37)(H,38,39)(H,27,28,32)(H2,33,34,35)/t19-,21-,22-,23-/m1/s1 YWGARZGMLXLDKP-JMJGKCIBSA-N 50013013 CHEMBL3261375 P2Y purinoceptor 4 Homo sapiens 47 ChEMBL 10.1021/jm500367e 10.7270/Q2V989M9 24712832 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Hammes, E; Balasubramanian, R; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013013&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 90656226 242058178 CHEMBL3261375 C03517 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50093857 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cc\c(=N\OCCCc2ccc(OCC(=O)NCCC#C)cc2)[nH]c1=O InChI=1S/C24H33N4O17P3/c1-2-3-11-25-20(29)15-40-17-8-6-16(7-9-17)5-4-13-41-27-19-10-12-28(24(32)26-19)23-22(31)21(30)18(43-23)14-42-47(36,37)45-48(38,39)44-46(33,34)35/h1,6-10,12,18,21-23,30-31H,3-5,11,13-15H2,(H,25,29)(H,36,37)(H,38,39)(H,26,27,32)(H2,33,34,35)/t18-,21-,22-,23-/m1/s1 XFDQWGJBBWWSOY-RLLPEYFOSA-N 50013014 CHEMBL3261376 P2Y purinoceptor 4 Homo sapiens 40 ChEMBL 10.1021/jm500367e 10.7270/Q2V989M9 24712832 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Hammes, E; Balasubramanian, R; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013014&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 90656227 242058179 CHEMBL3261376 C03517 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50093858 Nc1ccc2c(-c3ccc(cc3C([O-])=O)C(=O)NCCCCCCn3cc(CCNC(=O)COc4ccc(CCCO\N=c5\ccn([C@@H]6O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]6O)c(=O)[nH]5)cc4)nn3)c3ccc(=[NH2+])c(c3oc2c1S([O-])(=O)=O)S([O-])(=O)=O InChI=1S/C51H59N10O27P3S2.2C6H15N/c52-36-15-13-33-41(34-14-16-37(53)47(93(79,80)81)45(34)86-44(33)46(36)92(76,77)78)32-12-9-29(24-35(32)50(66)67)48(65)55-19-3-1-2-4-21-60-25-30(57-59-60)17-20-54-40(62)27-82-31-10-7-28(8-11-31)6-5-23-83-58-39-18-22-61(51(68)56-39)49-43(64)42(63)38(85-49)26-84-90(72,73)88-91(74,75)87-89(69,70)71;2*1-4-7(5-2)6-3/h7-16,18,22,24-25,38,42-43,49,52,63-64H,1-6,17,19-21,23,26-27,53H2,(H,54,62)(H,55,65)(H,66,67)(H,72,73)(H,74,75)(H,56,58,68)(H2,69,70,71)(H,76,77,78)(H,79,80,81);2*4-6H2,1-3H3/t38-,42-,43-,49-;;/m1../s1 CYHLQEIGNQACKC-FDZRIHCXSA-N 50013028 CHEMBL3261377 P2Y purinoceptor 4 Homo sapiens 200 ChEMBL 10.1021/jm500367e 10.7270/Q2V989M9 24712832 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Hammes, E; Balasubramanian, R; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013028&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 90656228 242058180 CHEMBL3261377 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50093864 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cc\c(=N\OCCCc2ccc(OCC(=O)NCCc3cn(CCCNC(=O)CCCCCNC(=O)COc4ccc(\C=C\c5ccc6C=C7C=CC(c8cccs8)=[N+]7[B-](F)(F)n56)cc4)nn3)cc2)[nH]c1=O InChI=1S/C56H67BF2N11O20P3S/c58-57(59)69-41(16-17-42(69)33-43-18-23-46(70(43)57)48-8-5-32-94-48)15-10-39-13-21-45(22-14-39)84-36-51(72)61-26-3-1-2-9-50(71)60-27-6-29-67-34-40(64-66-67)24-28-62-52(73)37-85-44-19-11-38(12-20-44)7-4-31-86-65-49-25-30-68(56(76)63-49)55-54(75)53(74)47(88-55)35-87-92(80,81)90-93(82,83)89-91(77,78)79/h5,8,10-23,25,30,32-34,47,53-55,74-75H,1-4,6-7,9,24,26-29,31,35-37H2,(H,60,71)(H,61,72)(H,62,73)(H,80,81)(H,82,83)(H,63,65,76)(H2,77,78,79)/b15-10+/t47-,53-,54-,55-/m1/s1 IKFGJXBDIZQEHP-NJFIWEGUSA-N 50013029 CHEMBL3261378 P2Y purinoceptor 4 Homo sapiens 70 ChEMBL 10.1021/jm500367e 10.7270/Q2V989M9 24712832 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Hammes, E; Balasubramanian, R; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013029&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 90656230 242058181 CHEMBL3261378 C03517 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50093912 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cc\c(=N\OCCCc3ccccc3)[nH]c2=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C27H37N5O23P4/c33-19-9-11-32(27(39)29-19)25-23(37)21(35)17(52-25)14-50-57(42,43)54-59(46,47)55-58(44,45)53-56(40,41)49-13-16-20(34)22(36)24(51-16)31-10-8-18(28-26(31)38)30-48-12-4-7-15-5-2-1-3-6-15/h1-3,5-6,8-11,16-17,20-25,34-37H,4,7,12-14H2,(H,40,41)(H,42,43)(H,44,45)(H,46,47)(H,28,30,38)(H,29,33,39)/t16-,17-,20-,21-,22-,23-,24-,25-/m1/s1 FNDQFKHGGXLPEC-MQCKZRQRSA-N 50013030 CHEMBL3261379 P2Y purinoceptor 4 Homo sapiens 93 ChEMBL 10.1021/jm500367e 10.7270/Q2V989M9 24712832 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Hammes, E; Balasubramanian, R; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013030&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 90656231 242058182 CHEMBL3261379 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50093913 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cc\c(=N\OCCCc3ccccc3)[nH]c2=O)O[C@H]([C@@H]1O)n1cc\c(=N\OCCCc2ccccc2)[nH]c1=O InChI=1S/C36H48N6O23P4/c43-29-25(61-33(31(29)45)41-17-15-27(37-35(41)47)39-57-19-7-13-23-9-3-1-4-10-23)21-59-66(49,50)63-68(53,54)65-69(55,56)64-67(51,52)60-22-26-30(44)32(46)34(62-26)42-18-16-28(38-36(42)48)40-58-20-8-14-24-11-5-2-6-12-24/h1-6,9-12,15-18,25-26,29-34,43-46H,7-8,13-14,19-22H2,(H,49,50)(H,51,52)(H,53,54)(H,55,56)(H,37,39,47)(H,38,40,48)/t25-,26-,29-,30-,31-,32-,33-,34-/m1/s1 QMCHGCVSODSXDQ-ZHELWVPESA-N 50013031 CHEMBL3261380 P2Y purinoceptor 4 Homo sapiens 1330 ChEMBL 10.1021/jm500367e 10.7270/Q2V989M9 24712832 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Hammes, E; Balasubramanian, R; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013031&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 90656232 242058183 CHEMBL3261380 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50173535 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C9H15N2O15P3/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1 PGAVKCOVUIYSFO-XVFCMESISA-N 50118213 5'-UTP::CHEMBL336296::H4utp::UTP::uridine 5'-(tetrahydrogen triphosphate)::uridine 5'-triphosphoric acid P2Y purinoceptor 4 Homo sapiens 90 ChEMBL 10.1021/jm101591j 10.7270/Q22F7NT0 21528910 Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118213&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search UTP 6133 104011550 15713 CHEMBL336296 1734 C03517 ZINC19796107 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50173538 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O)n1ccc(=O)[nH]c1=O InChI=1S/C18H26N4O23P4/c23-9-1-3-21(17(29)19-9)15-13(27)11(25)7(41-15)5-39-46(31,32)43-48(35,36)45-49(37,38)44-47(33,34)40-6-8-12(26)14(28)16(42-8)22-4-2-10(24)20-18(22)30/h1-4,7-8,11-16,25-28H,5-6H2,(H,31,32)(H,33,34)(H,35,36)(H,37,38)(H,19,23,29)(H,20,24,30)/p-4/t7-,8-,11-,12-,13-,14-,15-,16-/m1/s1 NMLMACJWHPHKGR-NCOIDOBVSA-J 50341879 CHEMBL1767408::Diquafosol P2Y purinoceptor 4 Homo sapiens 870 ChEMBL 10.1021/jm101591j 10.7270/Q22F7NT0 21528910 Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341879 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341879&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91932423 131344815 27791 CHEMBL1767408 C06198 ZINC85433146 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50172567 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)n1ccc(=S)[nH]c1=O InChI=1S/C9H15N2O14P3S/c12-6-4(3-22-27(18,19)25-28(20,21)24-26(15,16)17)23-8(7(6)13)11-2-1-5(29)10-9(11)14/h1-2,4,6-8,12-13H,3H2,(H,18,19)(H,20,21)(H,10,14,29)(H2,15,16,17)/t4-,6-,7-,8-/m1/s1 GKVHYBAWZAYQDO-XVFCMESISA-N 50341880 ((2R,3S,4R,5R)-3,4-dihydroxy-5-(2-oxo-4-thioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl triphosphate::CHEMBL1767409 P2Y purinoceptor 4 Homo sapiens 23 ChEMBL 10.1021/jm1016297 10.7270/Q2VT1SFC 21417463 El-Tayeb, A; Qi, A; Nicholas, RA; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341880 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341880&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 3033941 131344816 CHEMBL1767409 1730 C03517 ZINC13527358 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50203122 CNc1nc(Cl)nc2n(cnc12)[C@H]1C[C@@H](OP(O)(O)=O)[C@]2(COP(O)(O)=O)C[C@H]12 InChI=1S/C13H18ClN5O8P2/c1-15-10-9-11(18-12(14)17-10)19(5-16-9)7-2-8(27-29(23,24)25)13(3-6(7)13)4-26-28(20,21)22/h5-8H,2-4H2,1H3,(H,15,17,18)(H2,20,21,22)(H2,23,24,25)/t6-,7+,8-,13+/m1/s1 NDCFGYFBDZLTJB-LJYOZPSBSA-N 50026893 CHEMBL3085531 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/jm020046y 10.7270/Q2VX0H71 12213051 Jacobson, KA; Jarvis, MF; Williams, M National Institute of Diabetes http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026893 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026893&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 76324375 103936477 CHEMBL3085531 ZINC02567918 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50200793 [BH3-]P(=O)(OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O)OP([O-])(=O)OP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C18H28BN4O22P4/c19-46(32,39-5-7-11(26)13(28)15(41-7)22-3-1-9(24)20-17(22)30)43-48(35,36)45-49(37,38)44-47(33,34)40-6-8-12(27)14(29)16(42-8)23-4-2-10(25)21-18(23)31/h1-4,7-8,11-16,26-29H,5-6H2,19H3,(H,33,34)(H,35,36)(H,37,38)(H,20,24,30)(H,21,25,31)/q-1/p-3/t7-,8-,11-,12-,13-,14-,15-,16-,46?/m1/s1 QHGIIPGNSPHLFM-VMOKYWTHSA-K 50364066 CHEMBL1950678 P2Y purinoceptor 4 Homo sapiens 9400 ChEMBL 10.1021/jm2013198 10.7270/Q2Z60PJT 22107038 Yelovitch, S; Camden, J; Weisman, GA; Fischer, B Bar-Ilan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50364066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50364066&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91930575 136968128 CHEMBL1950678 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50578777 CC(C)(C)ONc1ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)n1 InChI=1S/C13H23N3O12P2/c1-13(2,3)27-15-8-4-5-16(12(19)14-8)11-10(18)9(17)7(26-11)6-25-30(23,24)28-29(20,21)22/h4-5,7,9-11,17-18H,6H2,1-3H3,(H,23,24)(H,14,15,19)(H2,20,21,22)/t7-,9-,10-,11-/m1/s1 CHTRDLZHJUNBLO-QCNRFFRDSA-N 50319126 CHEMBL1084296::N4-tert-Butyloxycytidine 5'-Diphosphate triethylammonium Salt P2Y purinoceptor 4 Homo sapiens 6230 ChEMBL 10.1021/jm100287t 10.7270/Q2RB74SH 20446735 Maruoka, H; Barrett, MO; Ko, H; Tosh, DK; Melman, A; Burianek, LE; Balasubramanian, R; Berk, B; Costanzi, S; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50319126 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50319126&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 46831386 104153487 CHEMBL1084296 C03517 ZINC49089302 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50578780 CONc1ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)n1 InChI=1S/C10H17N3O12P2/c1-22-12-6-2-3-13(10(16)11-6)9-8(15)7(14)5(24-9)4-23-27(20,21)25-26(17,18)19/h2-3,5,7-9,14-15H,4H2,1H3,(H,20,21)(H,11,12,16)(H2,17,18,19)/t5-,7-,8-,9-/m1/s1 GSCCOZXWAPBMKO-ZOQUXTDFSA-N 50319129 CHEMBL1084020::CHEMBL1204010::N4-Methoxycytidine 5'-Diphosphate triethylammonium Salt P2Y purinoceptor 4 Homo sapiens 6450 ChEMBL 10.1021/jm100287t 10.7270/Q2RB74SH 20446735 Maruoka, H; Barrett, MO; Ko, H; Tosh, DK; Melman, A; Burianek, LE; Balasubramanian, R; Berk, B; Costanzi, S; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50319129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50319129&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 45485253 104153490 CHEMBL1084020CHEMBL1204010 C03517 ZINC45335021 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50578802 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(NOCc2ccccc2)nc1=O InChI=1S/C16H21N3O12P2/c20-13-11(9-29-33(26,27)31-32(23,24)25)30-15(14(13)21)19-7-6-12(17-16(19)22)18-28-8-10-4-2-1-3-5-10/h1-7,11,13-15,20-21H,8-9H2,(H,26,27)(H,17,18,22)(H2,23,24,25)/t11-,13-,14-,15-/m1/s1 YNDKQBMZPIWHEC-NMFUWQPSSA-N 50319131 CHEMBL1084612::N4-Benzyloxycytidine 5'-Diphosphate triethylammonium Salt P2Y purinoceptor 4 Homo sapiens 1150 ChEMBL 10.1021/jm100287t 10.7270/Q2RB74SH 20446735 Maruoka, H; Barrett, MO; Ko, H; Tosh, DK; Melman, A; Burianek, LE; Balasubramanian, R; Berk, B; Costanzi, S; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50319131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50319131&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 46831686 104153492 CHEMBL1084612 C03517 ZINC49045225 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50578803 CONc1ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n3ccc(=O)[nH]c3=O)[C@@H](O)[C@H]2O)c(=O)n1 InChI=1S/C19H28N5O20P3/c1-38-22-10-2-4-23(18(30)20-10)16-14(28)12(26)8(41-16)6-39-45(32,33)43-47(36,37)44-46(34,35)40-7-9-13(27)15(29)17(42-9)24-5-3-11(25)21-19(24)31/h2-5,8-9,12-17,26-29H,6-7H2,1H3,(H,32,33)(H,34,35)(H,36,37)(H,20,22,30)(H,21,25,31)/t8-,9-,12-,13-,14-,15-,16-,17-/m1/s1 SIKKMGJHOOQSAP-RTGFKBDUSA-N 50319139 CHEMBL1083256::P1-Uridine5'-P3-Cyclohexyltriphosphate TriethylammoniumSalt P2Y purinoceptor 4 Homo sapiens 790 ChEMBL 10.1021/jm100287t 10.7270/Q2RB74SH 20446735 Maruoka, H; Barrett, MO; Ko, H; Tosh, DK; Melman, A; Burianek, LE; Balasubramanian, R; Berk, B; Costanzi, S; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50319139 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50319139&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 46830491 104153500 CHEMBL1083256 ZINC95538238 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50578804 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C18H25N4O20P3/c23-9-1-3-21(17(29)19-9)15-13(27)11(25)7(39-15)5-37-43(31,32)41-45(35,36)42-44(33,34)38-6-8-12(26)14(28)16(40-8)22-4-2-10(24)20-18(22)30/h1-4,7-8,11-16,25-28H,5-6H2,(H,31,32)(H,33,34)(H,35,36)(H,19,23,29)(H,20,24,30)/t7-,8-,11-,12-,13-,14-,15-,16-/m1/s1 JPNWHMPVXHYIKN-NCOIDOBVSA-N 50241299 CHEMBL239151::{[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphinic acid P2Y purinoceptor 4 Homo sapiens 870 ChEMBL 10.1021/jm100287t 10.7270/Q2RB74SH 20446735 Maruoka, H; Barrett, MO; Ko, H; Tosh, DK; Melman, A; Burianek, LE; Balasubramanian, R; Berk, B; Costanzi, S; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241299&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 9875011 104098700 CHEMBL239151 ZINC49946842 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50578807 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H]2C[C@]2([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C11H17N2O14P3/c14-7-1-2-13(10(17)12-7)11-3-6(11)5(8(15)9(11)16)4-25-29(21,22)27-30(23,24)26-28(18,19)20/h1-2,5-6,8-9,15-16H,3-4H2,(H,21,22)(H,23,24)(H,12,14,17)(H2,18,19,20)/t5-,6-,8+,9+,11-/m0/s1 ZLMXVYJQUSHKBL-UVWAWMSZSA-N 50319140 (S)-Methanocarbauridine5'-Triphosphate TriethylammoniumSalt::CHEMBL1083148 P2Y purinoceptor 4 Homo sapiens 300 ChEMBL 10.1021/jm100287t 10.7270/Q2RB74SH 20446735 Maruoka, H; Barrett, MO; Ko, H; Tosh, DK; Melman, A; Burianek, LE; Balasubramanian, R; Berk, B; Costanzi, S; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50319140 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50319140&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 46890063 104153501 CHEMBL1083148 C03517 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50578812 CONc1ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n3ccc(NOC)nc3=O)[C@@H](O)[C@H]2O)c(=O)n1 InChI=1S/C20H31N6O20P3/c1-39-23-11-3-5-25(19(31)21-11)17-15(29)13(27)9(43-17)7-41-47(33,34)45-49(37,38)46-48(35,36)42-8-10-14(28)16(30)18(44-10)26-6-4-12(24-40-2)22-20(26)32/h3-6,9-10,13-18,27-30H,7-8H2,1-2H3,(H,33,34)(H,35,36)(H,37,38)(H,21,23,31)(H,22,24,32)/t9-,10-,13-,14-,15-,16-,17-,18-/m1/s1 VRDDLMOUKGBIFO-ZNYGVHBGSA-N 50319130 ((((2R,3S,4R,5R)-3,4-dihydroxy-5-((E)-4-(methoxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)methylphosphonic(((2R,3S,4R,5R)-3,4-dihydroxy-5-(4-(methoxyamino)-2-oxopyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl phosphoric)anhydride::CHEMBL1083257 P2Y purinoceptor 4 Homo sapiens 560 ChEMBL 10.1021/jm100287t 10.7270/Q2RB74SH 20446735 Maruoka, H; Barrett, MO; Ko, H; Tosh, DK; Melman, A; Burianek, LE; Balasubramanian, R; Berk, B; Costanzi, S; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50319130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50319130&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 46830492 104153491 CHEMBL1083257 ZINC95538365 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50578816 CCONc1ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)n1 InChI=1S/C11H19N3O12P2/c1-2-23-13-7-3-4-14(11(17)12-7)10-9(16)8(15)6(25-10)5-24-28(21,22)26-27(18,19)20/h3-4,6,8-10,15-16H,2,5H2,1H3,(H,21,22)(H,12,13,17)(H2,18,19,20)/t6-,8-,9-,10-/m1/s1 GIRDCYBYUOKKAL-PEBGCTIMSA-N 50319141 CHEMBL1084295::N4-Ethoxycytidine 5'-Diphosphate triethylAmmonium Salt P2Y purinoceptor 4 Homo sapiens 180 ChEMBL 10.1021/jm100287t 10.7270/Q2RB74SH 20446735 Maruoka, H; Barrett, MO; Ko, H; Tosh, DK; Melman, A; Burianek, LE; Balasubramanian, R; Berk, B; Costanzi, S; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50319141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50319141&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 46831384 104153502 CHEMBL1084295 C03517 ZINC49034717 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50578820 CONc1ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)n1 InChI=1S/C10H18N3O15P3/c1-24-12-6-2-3-13(10(16)11-6)9-8(15)7(14)5(26-9)4-25-30(20,21)28-31(22,23)27-29(17,18)19/h2-3,5,7-9,14-15H,4H2,1H3,(H,20,21)(H,22,23)(H,11,12,16)(H2,17,18,19)/t5-,7-,8-,9-/m1/s1 JFCPDJMYRHCAHH-ZOQUXTDFSA-N 50319143 CHEMBL1083764::CHEMBL1198849::N4-Methoxycytidine 5'-Triphosphate triethylammonium Salt P2Y purinoceptor 4 Homo sapiens 50 ChEMBL 10.1021/jm100287t 10.7270/Q2RB74SH 20446735 Maruoka, H; Barrett, MO; Ko, H; Tosh, DK; Melman, A; Burianek, LE; Balasubramanian, R; Berk, B; Costanzi, S; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50319143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50319143&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 46831692 104153504 CHEMBL1198849CHEMBL1083764 C03517 ZINC13516041 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50578828 O[C@H]1C[C@@H]([C@H]2C[C@]12COP(O)(=O)OP(O)(=O)OP(O)(O)=O)n1ccc(=O)[nH]c1=O InChI=1S/C11H17N2O13P3/c14-8-3-7(13-2-1-9(15)12-10(13)16)6-4-11(6,8)5-24-28(20,21)26-29(22,23)25-27(17,18)19/h1-2,6-8,14H,3-5H2,(H,20,21)(H,22,23)(H,12,15,16)(H2,17,18,19)/t6-,7+,8+,11-/m1/s1 RPNVUPIADXEPEY-OFHVYEONSA-N 50319144 ((1S,2S,4S,5S)-4-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-hydroxybicyclo[3.1.0]hexan-1-yl)methyl tetrahydrogen triphosphate::CHEMBL1083763 P2Y purinoceptor 4 Homo sapiens 85 ChEMBL 10.1021/jm100287t 10.7270/Q2RB74SH 20446735 Maruoka, H; Barrett, MO; Ko, H; Tosh, DK; Melman, A; Burianek, LE; Balasubramanian, R; Berk, B; Costanzi, S; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50319144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50319144&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 46890111 104153505 CHEMBL1083763 C03517 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50635146 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O)n1ccc(=O)[nH]c1=O InChI=1S/C18H26N4O23P4/c23-9-1-3-21(17(29)19-9)15-13(27)11(25)7(41-15)5-39-46(31,32)43-48(35,36)45-49(37,38)44-47(33,34)40-6-8-12(26)14(28)16(42-8)22-4-2-10(24)20-18(22)30/h1-4,7-8,11-16,25-28H,5-6H2,(H,31,32)(H,33,34)(H,35,36)(H,37,38)(H,19,23,29)(H,20,24,30)/p-4/t7-,8-,11-,12-,13-,14-,15-,16-/m1/s1 NMLMACJWHPHKGR-NCOIDOBVSA-J 50341879 CHEMBL1767408::Diquafosol P2Y purinoceptor 4 Homo sapiens 400 ChEMBL 10.1021/jm1016297 10.7270/Q2VT1SFC 21417463 El-Tayeb, A; Qi, A; Nicholas, RA; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341879 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341879&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91932423 131344815 27791 CHEMBL1767408 C06198 ZINC85433146 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50635150 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)n1ccc(=S)[nH]c1=O InChI=1S/C9H15N2O14P3S/c12-6-4(3-22-27(18,19)25-28(20,21)24-26(15,16)17)23-8(7(6)13)11-2-1-5(29)10-9(11)14/h1-2,4,6-8,12-13H,3H2,(H,18,19)(H,20,21)(H,10,14,29)(H2,15,16,17)/t4-,6-,7-,8-/m1/s1 GKVHYBAWZAYQDO-XVFCMESISA-N 50341880 ((2R,3S,4R,5R)-3,4-dihydroxy-5-(2-oxo-4-thioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl triphosphate::CHEMBL1767409 P2Y purinoceptor 4 Homo sapiens 23 ChEMBL 10.1021/jm1016297 10.7270/Q2VT1SFC 21417463 El-Tayeb, A; Qi, A; Nicholas, RA; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341880 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341880&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 3033941 131344816 CHEMBL1767409 1730 C03517 ZINC13527358 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50635176 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C9H14N2O12P2/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1 XCCTYIAWTASOJW-XVFCMESISA-N 50118239 CHEMBL130266::UDP::Uridine diphosphate::uridine 5'-(trihydrogen diphosphate) P2Y purinoceptor 4 Homo sapiens 14000 ChEMBL 10.1021/jm1016297 10.7270/Q2VT1SFC 21417463 El-Tayeb, A; Qi, A; Nicholas, RA; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118239 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118239&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search UDP 6031 104011576 17659 CHEMBL130266 1749 C03517 ZINC12493522 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50635177 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C9H15N2O15P3/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1 PGAVKCOVUIYSFO-XVFCMESISA-N 50118213 5'-UTP::CHEMBL336296::H4utp::UTP::uridine 5'-(tetrahydrogen triphosphate)::uridine 5'-triphosphoric acid P2Y purinoceptor 4 Homo sapiens 88 ChEMBL 10.1021/jm1016297 10.7270/Q2VT1SFC 21417463 El-Tayeb, A; Qi, A; Nicholas, RA; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118213&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search UTP 6133 104011550 15713 CHEMBL336296 1734 C03517 ZINC19796107 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50635178 CSc1nc(=O)ccn1[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O InChI=1S/C10H16N2O11P2S/c1-26-10-11-6(13)2-3-12(10)9-8(15)7(14)5(22-9)4-21-25(19,20)23-24(16,17)18/h2-3,5,7-9,14-15H,4H2,1H3,(H,19,20)(H2,16,17,18)/t5-,7-,8-,9-/m1/s1 QJLQRMYFIFRKMR-ZOQUXTDFSA-N 50341881 2-methylthio-1-beta-D-ribofuranosylpyrimidine-4-one-5'-diphosphate::CHEMBL1767410 P2Y purinoceptor 4 Homo sapiens 1520 ChEMBL 10.1021/jm1016297 10.7270/Q2VT1SFC 21417463 El-Tayeb, A; Qi, A; Nicholas, RA; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341881 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341881&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 52952280 131344817 CHEMBL1767410 C03517 ZINC71329849 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50635179 CCCSc1nc(=O)ccn1[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O InChI=1S/C12H20N2O11P2S/c1-2-5-28-12-13-8(15)3-4-14(12)11-10(17)9(16)7(24-11)6-23-27(21,22)25-26(18,19)20/h3-4,7,9-11,16-17H,2,5-6H2,1H3,(H,21,22)(H2,18,19,20)/t7-,9-,10-,11-/m1/s1 PSPSPUIWAWTIGL-QCNRFFRDSA-N 50341882 2-propylthio-1-beta-D-ribofuranosylpyramidine-4-one-5'-diphosphate::CHEMBL1767411 P2Y purinoceptor 4 Homo sapiens 4900 ChEMBL 10.1021/jm1016297 10.7270/Q2VT1SFC 21417463 El-Tayeb, A; Qi, A; Nicholas, RA; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341882 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341882&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 52952281 131344818 CHEMBL1767411 C03517 ZINC71296730 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50635180 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)nc1SCc1ccccc1 InChI=1S/C16H20N2O11P2S/c19-12-6-7-18(16(17-12)32-9-10-4-2-1-3-5-10)15-14(21)13(20)11(28-15)8-27-31(25,26)29-30(22,23)24/h1-7,11,13-15,20-21H,8-9H2,(H,25,26)(H2,22,23,24)/t11-,13-,14-,15-/m1/s1 PFEYFSWPCKPKPU-NMFUWQPSSA-N 50341883 2-benzylthio-1-beta-D-ribofuranosylpyrimidine-4-one-5'-diphosphate::CHEMBL1767412 P2Y purinoceptor 4 Homo sapiens 5980 ChEMBL 10.1021/jm1016297 10.7270/Q2VT1SFC 21417463 El-Tayeb, A; Qi, A; Nicholas, RA; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341883 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341883&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 52952282 131344819 CHEMBL1767412 C03517 ZINC71316171 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50635181 COc1nc(=O)ccn1[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O InChI=1S/C10H16N2O12P2/c1-21-10-11-6(13)2-3-12(10)9-8(15)7(14)5(23-9)4-22-26(19,20)24-25(16,17)18/h2-3,5,7-9,14-15H,4H2,1H3,(H,19,20)(H2,16,17,18)/t5-,7-,8-,9-/m1/s1 LZLCEEVUQLXSAY-ZOQUXTDFSA-N 50341885 2-methoxy-1-beta-D-ribofuranosylpyrimidine-4-one-5'-diphosphate::CHEMBL1767414 P2Y purinoceptor 4 Homo sapiens 4490 ChEMBL 10.1021/jm1016297 10.7270/Q2VT1SFC 21417463 El-Tayeb, A; Qi, A; Nicholas, RA; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341885&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 52952391 131344821 CHEMBL1767414 C03517 ZINC71296335 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50635182 CSc1nc(=O)ccn1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O InChI=1S/C10H15N2O8PS/c1-22-10-11-6(13)2-3-12(10)9-8(15)7(14)5(20-9)4-19-21(16,17)18/h2-3,5,7-9,14-15H,4H2,1H3,(H2,16,17,18)/t5-,7-,8-,9-/m1/s1 VFWZRSQLLBLMNH-ZOQUXTDFSA-N 50341888 2-Methylthio-1-beta-D-ribofuranosylpyrimidine-4-one-5'-monophosphate::CHEMBL1767417 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/jm1016297 10.7270/Q2VT1SFC 21417463 El-Tayeb, A; Qi, A; Nicholas, RA; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341888&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 52952394 131344824 CHEMBL1767417 ZINC71329868 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50635183 CCSc1nc(=O)ccn1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O InChI=1S/C11H17N2O8PS/c1-2-23-11-12-7(14)3-4-13(11)10-9(16)8(15)6(21-10)5-20-22(17,18)19/h3-4,6,8-10,15-16H,2,5H2,1H3,(H2,17,18,19)/t6-,8-,9-,10-/m1/s1 HAIWBDSVRZGGKI-PEBGCTIMSA-N 50341889 2-Ethylthio-1-beta-D-ribofuranosylpyrimidine-4-one-5'-monophosphate::CHEMBL1767418 P2Y purinoceptor 4 Homo sapiens 4330 ChEMBL 10.1021/jm1016297 10.7270/Q2VT1SFC 21417463 El-Tayeb, A; Qi, A; Nicholas, RA; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341889 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341889&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 52952395 131344825 CHEMBL1767418 ZINC71319154 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50635184 CCCSc1nc(=O)ccn1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O InChI=1S/C12H19N2O8PS/c1-2-5-24-12-13-8(15)3-4-14(12)11-10(17)9(16)7(22-11)6-21-23(18,19)20/h3-4,7,9-11,16-17H,2,5-6H2,1H3,(H2,18,19,20)/t7-,9-,10-,11-/m1/s1 FENPKUDFWRAYIO-QCNRFFRDSA-N 50341890 2-Propylthio-1-beta-D-ribofuranosylpyrimidine-4-one-5'-monophosphate::CHEMBL1767419 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/jm1016297 10.7270/Q2VT1SFC 21417463 El-Tayeb, A; Qi, A; Nicholas, RA; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341890&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 52952396 131344826 CHEMBL1767419 ZINC71296303 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50635185 O[C@@H]1[C@@H](COP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)nc1SCc1ccccc1 InChI=1S/C16H19N2O8PS/c19-12-6-7-18(16(17-12)28-9-10-4-2-1-3-5-10)15-14(21)13(20)11(26-15)8-25-27(22,23)24/h1-7,11,13-15,20-21H,8-9H2,(H2,22,23,24)/t11-,13-,14-,15-/m1/s1 UAVDUKDOQBEXDY-NMFUWQPSSA-N 50341903 2-Benzylthio-1-beta-D-ribofuranosylpyrimidine-4-one-5'-monophosphate::CHEMBL1767420 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/jm1016297 10.7270/Q2VT1SFC 21417463 El-Tayeb, A; Qi, A; Nicholas, RA; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341903 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341903&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 52952397 131344839 CHEMBL1767420 ZINC71316949 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50635186 O[C@@H]1[C@@H](COP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)nc1SCCc1ccccc1 InChI=1S/C17H21N2O8PS/c20-13-6-8-19(17(18-13)29-9-7-11-4-2-1-3-5-11)16-15(22)14(21)12(27-16)10-26-28(23,24)25/h1-6,8,12,14-16,21-22H,7,9-10H2,(H2,23,24,25)/t12-,14-,15-,16-/m1/s1 DKLOPLNHUFXHPV-DTZQCDIJSA-N 50341891 2-Phenylethylthio-1-beta-D-ribofuranosylpyrimidine-4-one-5'-monophosphate::CHEMBL1767421 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/jm1016297 10.7270/Q2VT1SFC 21417463 El-Tayeb, A; Qi, A; Nicholas, RA; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341891 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341891&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 52952494 131344827 CHEMBL1767421 ZINC71318792 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50635187 COc1nc(=O)ccn1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O InChI=1S/C10H15N2O9P/c1-19-10-11-6(13)2-3-12(10)9-8(15)7(14)5(21-9)4-20-22(16,17)18/h2-3,5,7-9,14-15H,4H2,1H3,(H2,16,17,18)/t5-,7-,8-,9-/m1/s1 YZHHOKQNKLNAMB-ZOQUXTDFSA-N 50341892 2-Methoxy-1-beta-D-ribofuranosylpyrimidine-4-one-5'-monophosphate::CHEMBL1767422 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/jm1016297 10.7270/Q2VT1SFC 21417463 El-Tayeb, A; Qi, A; Nicholas, RA; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341892 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341892&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 52952495 131344828 CHEMBL1767422 ZINC71318032 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50635188 Nc1nc(=O)ccn1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O InChI=1S/C9H14N3O8P/c10-9-11-5(13)1-2-12(9)8-7(15)6(14)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,14-15H,3H2,(H2,10,11,13)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1 ONSQLDCEJIIUJS-XVFCMESISA-N 50341893 ((2R,3S,4R,5R)-5-(2-amino-4-oxopyrimidin-1(4H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate::CHEMBL1233534::ISOCYTIDINE-5'-MONOPHOSPHATE P2Y purinoceptor 4 Homo sapiens 4980 ChEMBL 10.1021/jm1016297 10.7270/Q2VT1SFC 21417463 El-Tayeb, A; Qi, A; Nicholas, RA; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341893 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341893&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search IC 49867142 131344829 CHEMBL1233534 6201 ZINC58638426 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50635189 CNc1nc(=O)ccn1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O InChI=1S/C10H16N3O8P/c1-11-10-12-6(14)2-3-13(10)9-8(16)7(15)5(21-9)4-20-22(17,18)19/h2-3,5,7-9,15-16H,4H2,1H3,(H,11,12,14)(H2,17,18,19)/t5-,7-,8-,9-/m1/s1 PCXZWACWCNBIAD-ZOQUXTDFSA-N 50341894 ((2R,3S,4R,5R)-3,4-dihydroxy-5-(2-(methylamino)-4-oxopyrimidin-1(4H)-yl)tetrahydrofuran-2-yl)methyl dihydrogen phosphate::CHEMBL1767423 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/jm1016297 10.7270/Q2VT1SFC 21417463 El-Tayeb, A; Qi, A; Nicholas, RA; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341894 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341894&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 52952496 131344830 CHEMBL1767423 ZINC71315750 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50635190 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(O)=O)n1ccc(=S)[nH]c1=O InChI=1S/C9H13N2O8PS/c12-6-4(3-18-20(15,16)17)19-8(7(6)13)11-2-1-5(21)10-9(11)14/h1-2,4,6-8,12-13H,3H2,(H,10,14,21)(H2,15,16,17)/t4-,6-,7-,8-/m1/s1 CKTAUHRBDDXUDJ-XVFCMESISA-N 50341895 ((2R,3S,4R,5R)-3,4-dihydroxy-5-(2-oxo-4-thioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl dihydrogen phosphate::4-THIOURIDINE-5'-MONOPHOSPHATE::4-THIOURIDINE-5'-PHOSPHATE::CHEMBL1230331 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/jm1016297 10.7270/Q2VT1SFC 21417463 El-Tayeb, A; Qi, A; Nicholas, RA; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341895 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341895&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 4SU 16655024 131344831 CHEMBL1230331 ZINC13518042 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50635191 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)C(Cl)(Cl)P(O)(O)=O)n1ccc(=O)n(CC(=O)c2ccccc2)c1=O InChI=1S/C18H21Cl2N2O15P3/c19-18(20,38(28,29)30)39(31,32)37-40(33,34)35-9-12-14(25)15(26)16(36-12)21-7-6-13(24)22(17(21)27)8-11(23)10-4-2-1-3-5-10/h1-7,12,14-16,25-26H,8-9H2,(H,31,32)(H,33,34)(H2,28,29,30)/t12-,14-,15-,16-/m1/s1 VFXKDYBJGPCICW-DTZQCDIJSA-N 50341897 3-Phenacyl-5'-uridylic Acid(1,1-Chloro-1-phosphonomethyl-1-phosphonyl)anhydride::CHEMBL1765115 P2Y purinoceptor 4 Homo sapiens 7300 ChEMBL 10.1021/jm1016297 10.7270/Q2VT1SFC 21417463 El-Tayeb, A; Qi, A; Nicholas, RA; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341897 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341897&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 52952497 131344833 CHEMBL1765115 ZINC72129913 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50635192 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)C(Cl)(Cl)P(O)(O)=O)n1ccc(=O)[nH]c1=S InChI=1S/C10H15Cl2N2O13P3S/c11-10(12,28(18,19)20)29(21,22)27-30(23,24)25-3-4-6(16)7(17)8(26-4)14-2-1-5(15)13-9(14)31/h1-2,4,6-8,16-17H,3H2,(H,21,22)(H,23,24)(H,13,15,31)(H2,18,19,20)/t4-,6-,7-,8-/m1/s1 BAIJAODZQNTGJN-XVFCMESISA-N 50271187 CHEMBL519835::[dichloro({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(4-oxo-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl})methyl]phosphonic acid P2Y purinoceptor 4 Homo sapiens 3850 ChEMBL 10.1021/jm1016297 10.7270/Q2VT1SFC 21417463 El-Tayeb, A; Qi, A; Nicholas, RA; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50271187 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50271187&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44585987 104116112 CHEMBL519835 ZINC42878349 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50635193 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)C(Cl)(Cl)P(O)(O)=O)n1ccc(=S)[nH]c1=O InChI=1S/C10H15Cl2N2O13P3S/c11-10(12,28(18,19)20)29(21,22)27-30(23,24)25-3-4-6(15)7(16)8(26-4)14-2-1-5(31)13-9(14)17/h1-2,4,6-8,15-16H,3H2,(H,21,22)(H,23,24)(H,13,17,31)(H2,18,19,20)/t4-,6-,7-,8-/m1/s1 LUWOVOPRCPGURH-XVFCMESISA-N 50341898 4-Thio-5'-uridylic Acid(1,1-Chloro-1-phosphonomethyl-1-phosphonyl)anhydride::CHEMBL1765116 P2Y purinoceptor 4 Homo sapiens 7870 ChEMBL 10.1021/jm1016297 10.7270/Q2VT1SFC 21417463 El-Tayeb, A; Qi, A; Nicholas, RA; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341898 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341898&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 52952603 131344834 CHEMBL1765116 ZINC71316914 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50635194 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)C(F)(F)P(O)(O)=O)n1ccc(=O)[nH]c1=O InChI=1S/C10H15F2N2O14P3/c11-10(12,29(19,20)21)30(22,23)28-31(24,25)26-3-4-6(16)7(17)8(27-4)14-2-1-5(15)13-9(14)18/h1-2,4,6-8,16-17H,3H2,(H,22,23)(H,24,25)(H,13,15,18)(H2,19,20,21)/t4-,6-,7-,8-/m1/s1 GMYHHUUHBVBEKO-XVFCMESISA-N 50341899 (((((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryloxy)(hydroxy)phosphoryl)difluoromethylphosphonic acid::CHEMBL1765117 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/jm1016297 10.7270/Q2VT1SFC 21417463 El-Tayeb, A; Qi, A; Nicholas, RA; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341899 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341899&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 11606036 131344835 CHEMBL1765117 ZINC71316198 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50635195 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)C(F)(F)P(O)(O)=O)n1ccc(=O)n(CC(=O)c2ccccc2)c1=O InChI=1S/C18H21F2N2O15P3/c19-18(20,38(28,29)30)39(31,32)37-40(33,34)35-9-12-14(25)15(26)16(36-12)21-7-6-13(24)22(17(21)27)8-11(23)10-4-2-1-3-5-10/h1-7,12,14-16,25-26H,8-9H2,(H,31,32)(H,33,34)(H2,28,29,30)/t12-,14-,15-,16-/m1/s1 CSVGAEIOFXFKIT-DTZQCDIJSA-N 50341900 3-Phenacyl-5'-uridylic Acid(1,1-Difluoro-1-phosphonomethyl-1-phosphonyl)anhydride::CHEMBL1765118 P2Y purinoceptor 4 Homo sapiens 3930 ChEMBL 10.1021/jm1016297 10.7270/Q2VT1SFC 21417463 El-Tayeb, A; Qi, A; Nicholas, RA; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341900 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341900&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 52952604 131344836 CHEMBL1765118 ZINC72131677 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50635196 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)C(F)(F)P(O)(O)=O)n1ccc(=S)[nH]c1=O InChI=1S/C10H15F2N2O13P3S/c11-10(12,28(18,19)20)29(21,22)27-30(23,24)25-3-4-6(15)7(16)8(26-4)14-2-1-5(31)13-9(14)17/h1-2,4,6-8,15-16H,3H2,(H,21,22)(H,23,24)(H,13,17,31)(H2,18,19,20)/t4-,6-,7-,8-/m1/s1 DFGBPSGNGNHNQM-XVFCMESISA-N 50341901 4-Thio-5'-uridylic Acid(1,1-Difluoro-1-phosphonomethyl-1-phosphonyl)anhydride::CHEMBL1765119 P2Y purinoceptor 4 Homo sapiens 9300 ChEMBL 10.1021/jm1016297 10.7270/Q2VT1SFC 21417463 El-Tayeb, A; Qi, A; Nicholas, RA; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341901 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341901&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 52952605 131344837 CHEMBL1765119 5902 ZINC71296342 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50635197 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(=O)Nc1ccccc1)n1cc(Br)c(=O)[nH]c1=O InChI=1S/C15H19BrN3O14P3/c16-9-6-19(15(23)17-13(9)22)14-12(21)11(20)10(31-14)7-30-35(26,27)33-36(28,29)32-34(24,25)18-8-4-2-1-3-5-8/h1-6,10-12,14,20-21H,7H2,(H,26,27)(H,28,29)(H,17,22,23)(H2,18,24,25)/t10-,11-,12-,14-/m1/s1 BECOTGWWMSOOEA-HKUMRIAESA-N 50341902 5-Bromo-1-beta-D-ribofuranosyl(3H)pyrimidine-2,4-dione 5'-(gamma-phenylamino)triphosphate::CHEMBL1765120 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/jm1016297 10.7270/Q2VT1SFC 21417463 El-Tayeb, A; Qi, A; Nicholas, RA; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341902 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341902&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 52952183 131344838 CHEMBL1765120 ZINC72131678 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50635223 Nc1ccn([C@H]2C[C@H](O)[C@@H](COP([O-])(=O)OP([O-])(=O)OP([O-])(=O)OP([O-])(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n3ccc(=O)[nH]c3=O)O2)c(=O)n1 InChI=1S/C18H27N5O21P4/c19-11-1-3-22(17(28)20-11)13-5-8(24)9(40-13)6-38-45(30,31)42-47(34,35)44-48(36,37)43-46(32,33)39-7-10-14(26)15(27)16(41-10)23-4-2-12(25)21-18(23)29/h1-4,8-10,13-16,24,26-27H,5-7H2,(H,30,31)(H,32,33)(H,34,35)(H,36,37)(H2,19,20,28)(H,21,25,29)/p-4/t8-,9+,10+,13+,14+,15+,16+/m0/s1 FPNPSEMJLALQSA-MIYUEGBISA-J 50341904 CHEMBL1767407::[P(1)-(uridine 5')-P(4)-(2'-deoxycytidine 5')tetraphosphate,tetrasodium salt] P2Y purinoceptor 4 Homo sapiens 800 ChEMBL 10.1021/jm1016297 10.7270/Q2VT1SFC 21417463 El-Tayeb, A; Qi, A; Nicholas, RA; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341904 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341904&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91932424 131344840 CHEMBL1767407 ZINC85540154 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50643296 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1N=[N+]=[N-])n1ccc(=O)[nH]c1=O InChI=1S/C9H14N5O14P3/c10-13-12-6-7(16)4(26-8(6)14-2-1-5(15)11-9(14)17)3-25-30(21,22)28-31(23,24)27-29(18,19)20/h1-2,4,6-8,16H,3H2,(H,21,22)(H,23,24)(H,11,15,17)(H2,18,19,20)/t4-,6-,7-,8-/m1/s1 JKLOYZCVXRYXFE-XVFCMESISA-N 50345480 ((2R,3S,4R,5R)-4-azido-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate::CHEMBL1784888 P2Y purinoceptor 4 Homo sapiens 1100 ChEMBL 10.1021/jm101591j 10.7270/Q22F7NT0 21528910 Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345480&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 54584406 131348411 CHEMBL1784888 C03517 ZINC71294389 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50643327 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C9H15N2O15P3/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1 PGAVKCOVUIYSFO-XVFCMESISA-N 50118213 5'-UTP::CHEMBL336296::H4utp::UTP::uridine 5'-(tetrahydrogen triphosphate)::uridine 5'-triphosphoric acid P2Y purinoceptor 4 Homo sapiens 80 ChEMBL 10.1021/jm101591j 10.7270/Q22F7NT0 21528910 Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118213&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search UTP 6133 104011550 15713 CHEMBL336296 1734 C03517 ZINC19796107 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50643328 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O)n1ccc(=O)[nH]c1=O InChI=1S/C18H26N4O23P4/c23-9-1-3-21(17(29)19-9)15-13(27)11(25)7(41-15)5-39-46(31,32)43-48(35,36)45-49(37,38)44-47(33,34)40-6-8-12(26)14(28)16(42-8)22-4-2-10(24)20-18(22)30/h1-4,7-8,11-16,25-28H,5-6H2,(H,31,32)(H,33,34)(H,35,36)(H,37,38)(H,19,23,29)(H,20,24,30)/p-4/t7-,8-,11-,12-,13-,14-,15-,16-/m1/s1 NMLMACJWHPHKGR-NCOIDOBVSA-J 50341879 CHEMBL1767408::Diquafosol P2Y purinoceptor 4 Homo sapiens 130 ChEMBL 10.1021/jm101591j 10.7270/Q22F7NT0 21528910 Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341879 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341879&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91932423 131344815 27791 CHEMBL1767408 C06198 ZINC85433146 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50643329 OC[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H](O)[C@@H]1O InChI=1S/C15H26N2O23P4/c18-3-5-8(20)10(22)12(24)14(36-5)37-42(28,29)39-44(32,33)40-43(30,31)38-41(26,27)34-4-6-9(21)11(23)13(35-6)17-2-1-7(19)16-15(17)25/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,30,31)(H,32,33)(H,16,19,25)/t5-,6-,8-,9-,10+,11-,12-,13-,14-/m1/s1 AJLLTXOUJGYGAA-JZMIEXBBSA-N 50270545 CHEMBL499138::Uridine-5'-glucose-1'-tetraphosphate P2Y purinoceptor 4 Homo sapiens 2060 ChEMBL 10.1021/jm101591j 10.7270/Q22F7NT0 21528910 Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270545 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270545&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44585518 104115716 CHEMBL499138 C01140 ZINC95540729 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50643330 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)n1ccc(=O)[nH]c1=S InChI=1S/C9H15N2O14P3S/c12-5-1-2-11(9(29)10-5)8-7(14)6(13)4(23-8)3-22-27(18,19)25-28(20,21)24-26(15,16)17/h1-2,4,6-8,13-14H,3H2,(H,18,19)(H,20,21)(H,10,12,29)(H2,15,16,17)/t4-,6-,7-,8-/m1/s1 KHYOUGAATNYCAZ-XVFCMESISA-N 50199176 2-thio-1-beta-D-ribofuranosyl(3H)pyrimidine-2,4-dione 5'-triphosphate::CHEMBL217803 P2Y purinoceptor 4 Homo sapiens 350 ChEMBL 10.1021/jm101591j 10.7270/Q22F7NT0 21528910 Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199176&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 10174453 104079840 CHEMBL217803 C03517 ZINC13540486 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50643331 CONc1ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)n1 InChI=1S/C10H18N3O15P3/c1-24-12-6-2-3-13(10(16)11-6)9-8(15)7(14)5(26-9)4-25-30(20,21)28-31(22,23)27-29(17,18)19/h2-3,5,7-9,14-15H,4H2,1H3,(H,20,21)(H,22,23)(H,11,12,16)(H2,17,18,19)/t5-,7-,8-,9-/m1/s1 JFCPDJMYRHCAHH-ZOQUXTDFSA-N 50319143 CHEMBL1083764::CHEMBL1198849::N4-Methoxycytidine 5'-Triphosphate triethylammonium Salt P2Y purinoceptor 4 Homo sapiens 25 ChEMBL 10.1021/jm101591j 10.7270/Q22F7NT0 21528910 Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50319143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50319143&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 46831692 104153504 CHEMBL1198849CHEMBL1083764 C03517 ZINC13516041 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50643332 CCONc1ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)n1 InChI=1S/C11H20N3O15P3/c1-2-25-13-7-3-4-14(11(17)12-7)10-9(16)8(15)6(27-10)5-26-31(21,22)29-32(23,24)28-30(18,19)20/h3-4,6,8-10,15-16H,2,5H2,1H3,(H,21,22)(H,23,24)(H,12,13,17)(H2,18,19,20)/t6-,8-,9-,10-/m1/s1 NXRKGUXDYPFZFP-PEBGCTIMSA-N 50345482 CHEMBL1784890::N4-Ethoxycytidine-5'-triphosphate P2Y purinoceptor 4 Homo sapiens 210 ChEMBL 10.1021/jm101591j 10.7270/Q22F7NT0 21528910 Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345482 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345482&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 53308826 131348413 CHEMBL1784890 C03517 ZINC71296040 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50643333 CC(C)(C)ONc1ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)n1 InChI=1S/C13H24N3O15P3/c1-13(2,3)29-15-8-4-5-16(12(19)14-8)11-10(18)9(17)7(28-11)6-27-33(23,24)31-34(25,26)30-32(20,21)22/h4-5,7,9-11,17-18H,6H2,1-3H3,(H,23,24)(H,25,26)(H,14,15,19)(H2,20,21,22)/t7-,9-,10-,11-/m1/s1 UJSOQUAGCZVHGO-QCNRFFRDSA-N 50345483 CHEMBL1784891::N4-t-Butyloxycytidine-5'-triphosphate P2Y purinoceptor 4 Homo sapiens 2110 ChEMBL 10.1021/jm101591j 10.7270/Q22F7NT0 21528910 Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345483&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 53308961 131348414 CHEMBL1784891 C03517 ZINC71296176 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50643334 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(NOCc2ccccc2)nc1=O InChI=1S/C16H22N3O15P3/c20-13-11(9-31-36(26,27)34-37(28,29)33-35(23,24)25)32-15(14(13)21)19-7-6-12(17-16(19)22)18-30-8-10-4-2-1-3-5-10/h1-7,11,13-15,20-21H,8-9H2,(H,26,27)(H,28,29)(H,17,18,22)(H2,23,24,25)/t11-,13-,14-,15-/m1/s1 BQIJGMRNEJCCQG-NMFUWQPSSA-N 50345484 CHEMBL1784892::N4-Benzyloxycytidine-5'-triphosphate P2Y purinoceptor 4 Homo sapiens 97 ChEMBL 10.1021/jm101591j 10.7270/Q22F7NT0 21528910 Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345484&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 53308272 131348415 CHEMBL1784892 C03517 ZINC71282457 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50643335 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(NOCCc2ccccc2)nc1=O InChI=1S/C17H24N3O15P3/c21-14-12(10-32-37(27,28)35-38(29,30)34-36(24,25)26)33-16(15(14)22)20-8-6-13(18-17(20)23)19-31-9-7-11-4-2-1-3-5-11/h1-6,8,12,14-16,21-22H,7,9-10H2,(H,27,28)(H,29,30)(H,18,19,23)(H2,24,25,26)/t12-,14-,15-,16-/m1/s1 WREOTYWODABZMH-DTZQCDIJSA-N 50345485 CHEMBL1784893::N4-Phenylethoxycytidine-5'-triphosphate P2Y purinoceptor 4 Homo sapiens 73 ChEMBL 10.1021/jm101591j 10.7270/Q22F7NT0 21528910 Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345485 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345485&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 53262890 131348416 CHEMBL1784893 6200 C03517 ZINC71296163 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50643336 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(NOCCCc2ccccc2)nc1=O InChI=1S/C18H26N3O15P3/c22-15-13(11-33-38(28,29)36-39(30,31)35-37(25,26)27)34-17(16(15)23)21-9-8-14(19-18(21)24)20-32-10-4-7-12-5-2-1-3-6-12/h1-3,5-6,8-9,13,15-17,22-23H,4,7,10-11H2,(H,28,29)(H,30,31)(H,19,20,24)(H2,25,26,27)/t13-,15-,16-,17-/m1/s1 FAYLMQPZASAIOS-MWQQHZPXSA-N 50345486 CHEMBL1784894::N4-Phenylpropoxycytidine-5'-triphosphate P2Y purinoceptor 4 Homo sapiens 23 ChEMBL 10.1021/jm101591j 10.7270/Q22F7NT0 21528910 Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345486 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345486&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 53262902 131348417 CHEMBL1784894 C03517 ZINC71294960 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50643337 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C9H16N2O18P4/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(26-8)3-25-31(19,20)28-33(23,24)29-32(21,22)27-30(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,23,24)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1 SBVYRQFJZOKNGO-XVFCMESISA-N 50271251 CHEMBL483502::{[({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}phosphonic acid P2Y purinoceptor 4 Homo sapiens 7300 ChEMBL 10.1021/jm101591j 10.7270/Q22F7NT0 21528910 Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50271251 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50271251&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 189010 104116140 CHEMBL483502 C03517 ZINC49872132 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50643338 COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C10H18N2O18P4/c1-25-31(17,18)28-33(21,22)30-34(23,24)29-32(19,20)26-4-5-7(14)8(15)9(27-5)12-3-2-6(13)11-10(12)16/h2-3,5,7-9,14-15H,4H2,1H3,(H,17,18)(H,19,20)(H,21,22)(H,23,24)(H,11,13,16)/t5-,7-,8-,9-/m1/s1 LRBUKMYVKOITTQ-ZOQUXTDFSA-N 50271289 CHEMBL519991::Uridine-5'-methyl-tetraphosphate P2Y purinoceptor 4 Homo sapiens 2700 ChEMBL 10.1021/jm101591j 10.7270/Q22F7NT0 21528910 Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50271289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50271289&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44586042 104116167 CHEMBL519991 ZINC42887869 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50643339 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OCCC#N)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C12H19N3O18P4/c13-3-1-5-28-34(20,21)31-36(24,25)33-37(26,27)32-35(22,23)29-6-7-9(17)10(18)11(30-7)15-4-2-8(16)14-12(15)19/h2,4,7,9-11,17-18H,1,5-6H2,(H,20,21)(H,22,23)(H,24,25)(H,26,27)(H,14,16,19)/t7-,9-,10-,11-/m1/s1 YXQHIYLIDUDMIY-QCNRFFRDSA-N 50271291 CHEMBL484105::Uridine-5'-(2-cyanoethyl)-tetraphosphate P2Y purinoceptor 4 Homo sapiens 1960 ChEMBL 10.1021/jm101591j 10.7270/Q22F7NT0 21528910 Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50271291 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50271291&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44586044 104116169 CHEMBL484105 ZINC49872213 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50643340 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)Oc1cccc(c1)[N+]([O-])=O)n1ccc(=O)[nH]c1=O InChI=1S/C15H19N3O20P4/c19-11-4-5-17(15(22)16-11)14-13(21)12(20)10(34-14)7-33-39(25,26)36-41(29,30)38-42(31,32)37-40(27,28)35-9-3-1-2-8(6-9)18(23)24/h1-6,10,12-14,20-21H,7H2,(H,25,26)(H,27,28)(H,29,30)(H,31,32)(H,16,19,22)/t10-,12-,13-,14-/m1/s1 YQIPYVWBJKTEKU-FMKGYKFTSA-N 50345490 CHEMBL1784900::Uridine-5'-(3-nitrophenyl)-tetraphosphate P2Y purinoceptor 4 Homo sapiens 2540 ChEMBL 10.1021/jm101591j 10.7270/Q22F7NT0 21528910 Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345490 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345490&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 53309242 131348421 CHEMBL1784900 ZINC72129834 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50643341 OC[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H](O)[C@H]1O InChI=1S/C15H26N2O23P4/c18-3-5-8(20)10(22)12(24)14(36-5)37-42(28,29)39-44(32,33)40-43(30,31)38-41(26,27)34-4-6-9(21)11(23)13(35-6)17-2-1-7(19)16-15(17)25/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,30,31)(H,32,33)(H,16,19,25)/t5-,6-,8+,9-,10+,11-,12-,13-,14-/m1/s1 AJLLTXOUJGYGAA-ABVWGUQPSA-N 50270546 CHEMBL444212::Uridine-5'-galactose-1'-tetraphosphate P2Y purinoceptor 4 Homo sapiens 1770 ChEMBL 10.1021/jm101591j 10.7270/Q22F7NT0 21528910 Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270546 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270546&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44585519 104115717 CHEMBL444212 ZINC95614922 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50643342 OC[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@H](O)[C@H](O)[C@@H]1O InChI=1S/C15H26N2O23P4/c18-3-5-8(20)10(22)12(24)14(36-5)37-42(28,29)39-44(32,33)40-43(30,31)38-41(26,27)34-4-6-9(21)11(23)13(35-6)17-2-1-7(19)16-15(17)25/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,30,31)(H,32,33)(H,16,19,25)/t5-,6-,8-,9-,10-,11-,12-,13-,14-/m1/s1 AJLLTXOUJGYGAA-NQQHDEILSA-N 50345491 CHEMBL1784885::Uridine-5'-allose-1'-tetraphosphate P2Y purinoceptor 4 Homo sapiens 183 ChEMBL 10.1021/jm101591j 10.7270/Q22F7NT0 21528910 Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345491 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345491&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 53309244 131348422 CHEMBL1784885 ZINC95547953 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50643343 OC[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@@H](O)[C@@H](O)[C@@H]1O InChI=1S/C15H26N2O23P4/c18-3-5-8(20)10(22)12(24)14(36-5)37-42(28,29)39-44(32,33)40-43(30,31)38-41(26,27)34-4-6-9(21)11(23)13(35-6)17-2-1-7(19)16-15(17)25/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,30,31)(H,32,33)(H,16,19,25)/t5-,6-,8-,9-,10+,11-,12+,13-,14-/m1/s1 AJLLTXOUJGYGAA-NYYOCOOHSA-N 50345492 CHEMBL1784886::Uridine-5'-mannose-1'-tetraphosphate P2Y purinoceptor 4 Homo sapiens 4480 ChEMBL 10.1021/jm101591j 10.7270/Q22F7NT0 21528910 Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345492 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345492&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 53309245 131348423 CHEMBL1784886 C02603 ZINC95547954 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50643344 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)O[C@H]2OC[C@@H](O)[C@H](O)[C@H]2O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C14H24N2O22P4/c17-5-3-32-13(11(22)8(5)19)35-40(26,27)37-42(30,31)38-41(28,29)36-39(24,25)33-4-6-9(20)10(21)12(34-6)16-2-1-7(18)15-14(16)23/h1-2,5-6,8-13,17,19-22H,3-4H2,(H,24,25)(H,26,27)(H,28,29)(H,30,31)(H,15,18,23)/t5-,6-,8+,9-,10-,11-,12-,13-/m1/s1 RNFGZTCOJKAIRF-OCIMBMBZSA-N 50345493 CHEMBL1784887::Uridine-5'-xylose-1'-tetraphosphate P2Y purinoceptor 4 Homo sapiens 620 ChEMBL 10.1021/jm101591j 10.7270/Q22F7NT0 21528910 Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345493&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 53309379 131348424 CHEMBL1784887 ZINC72110505 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50643345 CC(=O)N[C@H]1[C@@H](OP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)O[C@H](CO)[C@@H](O)[C@@H]1O InChI=1S/C17H29N3O23P4/c1-6(22)18-10-13(26)11(24)7(4-21)39-16(10)40-45(31,32)42-47(35,36)43-46(33,34)41-44(29,30)37-5-8-12(25)14(27)15(38-8)20-3-2-9(23)19-17(20)28/h2-3,7-8,10-16,21,24-27H,4-5H2,1H3,(H,18,22)(H,29,30)(H,31,32)(H,33,34)(H,35,36)(H,19,23,28)/t7-,8-,10-,11-,12-,13-,14-,15-,16-/m1/s1 SMSKYAZAKPGTPK-CFRASDGPSA-N 50345494 CHEMBL1784889::P1-(Uridine-5'-)P4-(2'-deoxy-2'-acetamidoglucose-1'-)tetraphosphate P2Y purinoceptor 4 Homo sapiens 910 ChEMBL 10.1021/jm101591j 10.7270/Q22F7NT0 21528910 Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345494 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345494&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 53309380 131348425 CHEMBL1784889 C03518 ZINC95548049 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50643346 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)O[C@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C15H24N2O24P4/c18-5-1-2-17(15(26)16-5)12-9(22)6(19)4(36-12)3-35-42(27,28)39-44(31,32)41-45(33,34)40-43(29,30)38-14-10(23)7(20)8(21)11(37-14)13(24)25/h1-2,4,6-12,14,19-23H,3H2,(H,24,25)(H,27,28)(H,29,30)(H,31,32)(H,33,34)(H,16,18,26)/t4-,6-,7+,8+,9-,10-,11+,12-,14-/m1/s1 NLYVASMWOWKGJP-LXQIFKJMSA-N 50345495 CHEMBL1784902::P1-(Uridine-5'-)P4-(glucuronic acid-1'-)tetraphosphate P2Y purinoceptor 4 Homo sapiens 227 ChEMBL 10.1021/jm101591j 10.7270/Q22F7NT0 21528910 Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345495&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 53309381 131348426 CHEMBL1784902 C06370 ZINC95547997 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50643347 OC[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H](F)[C@@H]1O InChI=1S/C15H25FN2O22P4/c16-8-9(21)5(3-19)36-14(11(8)23)37-42(28,29)39-44(32,33)40-43(30,31)38-41(26,27)34-4-6-10(22)12(24)13(35-6)18-2-1-7(20)17-15(18)25/h1-2,5-6,8-14,19,21-24H,3-4H2,(H,26,27)(H,28,29)(H,30,31)(H,32,33)(H,17,20,25)/t5-,6-,8+,9-,10-,11-,12-,13-,14-/m1/s1 IDFAEUCMIWFSPP-SAINOKEESA-N 50345496 CHEMBL1784904::P1-(Uridine-5'-)P4-(3'-deoxy-3'-fluoroglucose-1'-)tetraphosphate P2Y purinoceptor 4 Homo sapiens 62 ChEMBL 10.1021/jm101591j 10.7270/Q22F7NT0 21528910 Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345496 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345496&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 53262904 131348427 CHEMBL1784904 ZINC95548090 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50643348 OC[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(NOCc3ccccc3)nc2=O)[C@H](O)[C@@H](F)[C@@H]1O InChI=1S/C22H32FN3O22P4/c23-15-16(28)12(8-27)44-21(18(15)30)45-50(35,36)47-52(39,40)48-51(37,38)46-49(33,34)42-10-13-17(29)19(31)20(43-13)26-7-6-14(24-22(26)32)25-41-9-11-4-2-1-3-5-11/h1-7,12-13,15-21,27-31H,8-10H2,(H,33,34)(H,35,36)(H,37,38)(H,39,40)(H,24,25,32)/t12-,13-,15+,16-,17-,18-,19-,20-,21-/m1/s1 VNAVHLYUKQZQDG-PUTNOJKFSA-N 50345497 CHEMBL1784291::P1-(N4-Benzyloxycytidine-5'-)P4-(3'-deoxy-3'-fluoroglucose-1'-)tetraphosphate P2Y purinoceptor 4 Homo sapiens 670 ChEMBL 10.1021/jm101591j 10.7270/Q22F7NT0 21528910 Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345497 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345497&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 53309528 131348428 CHEMBL1784291 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50643349 CONc1ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)O[C@H]3O[C@H](CO)[C@@H](O)[C@H](F)[C@H]3O)[C@@H](O)[C@H]2O)c(=O)n1 InChI=1S/C16H28FN3O22P4/c1-35-19-8-2-3-20(16(26)18-8)14-13(25)11(23)7(37-14)5-36-43(27,28)40-45(31,32)42-46(33,34)41-44(29,30)39-15-12(24)9(17)10(22)6(4-21)38-15/h2-3,6-7,9-15,21-25H,4-5H2,1H3,(H,27,28)(H,29,30)(H,31,32)(H,33,34)(H,18,19,26)/t6-,7-,9+,10-,11-,12-,13-,14-,15-/m1/s1 URJOBJGVBHZRMG-YIPCRTQPSA-N 50345498 CHEMBL1784292::P1-(N4-Methoxycytidine-5'-)P4-(3'-deoxy-3'-fluoroglucose-1'-)tetraphosphate P2Y purinoceptor 4 Homo sapiens 310 ChEMBL 10.1021/jm101591j 10.7270/Q22F7NT0 21528910 Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345498 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345498&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 53309529 131348429 CHEMBL1784292 ZINC95548058 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50643350 OC[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H](O)[C@@H]1F InChI=1S/C15H25FN2O22P4/c16-8-5(3-19)36-14(12(24)10(8)22)37-42(28,29)39-44(32,33)40-43(30,31)38-41(26,27)34-4-6-9(21)11(23)13(35-6)18-2-1-7(20)17-15(18)25/h1-2,5-6,8-14,19,21-24H,3-4H2,(H,26,27)(H,28,29)(H,30,31)(H,32,33)(H,17,20,25)/t5-,6-,8-,9-,10+,11-,12-,13-,14-/m1/s1 NVBJHOWMMXNNQT-JZMIEXBBSA-N 50345499 CHEMBL1784293::P1-(Uridine-5'-)P4-(4'-deoxy-4'-fluoroglucose-1'-)tetraphosphate P2Y purinoceptor 4 Homo sapiens 220 ChEMBL 10.1021/jm101591j 10.7270/Q22F7NT0 21528910 Maruoka, H; Jayasekara, MP; Barrett, MO; Franklin, DA; de Castro, S; Kim, N; Costanzi, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345499 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345499&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 53309530 131348430 CHEMBL1784293 ZINC95548059 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50806993 Cc1ccc(cc1NC(=O)c1cccc(NC(=O)Nc2cccc(c2)C(=O)Nc2cc(ccc2C)C(=O)Nc2ccc(c3cc(cc(c23)S(O)(=O)=O)S(O)(=O)=O)S(O)(=O)=O)c1)C(=O)Nc1ccc(c2cc(cc(c12)S(O)(=O)=O)S(O)(=O)=O)S(O)(=O)=O InChI=1S/C51H40N6O23S6/c1-25-9-11-29(49(60)54-37-13-15-41(83(69,70)71)35-21-33(81(63,64)65)23-43(45(35)37)85(75,76)77)19-39(25)56-47(58)27-5-3-7-31(17-27)52-51(62)53-32-8-4-6-28(18-32)48(59)57-40-20-30(12-10-26(40)2)50(61)55-38-14-16-42(84(72,73)74)36-22-34(82(66,67)68)24-44(46(36)38)86(78,79)80/h3-24H,1-2H3,(H,54,60)(H,55,61)(H,56,58)(H,57,59)(H2,52,53,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80) FIAFUQMPZJWCLV-UHFFFAOYSA-N 50336799 5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino)]tris[1,3-benzenesulfonate analogue::8,8'-(Carbonylbis(imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino))bisnaphthalene-1,3,5-trisulphonic acid::8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFONIC ACID::8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonyl-imino]]bis-1,3,5-naphthalenetrisulfonic acid(suramin)::8-[(4-methyl-3-{[3-({[3-({2-methyl-5-[(4,6,8-trisulfonaphthalen-1-yl)carbamoyl]phenyl}carbamoyl)phenyl]carbamoyl}amino)benzene]amido}benzene)amido]naphthalene-1,3,5-trisulfonic acid::CHEMBL265502::Germanin::Suramin hexasodium::US8835659, Suramin::Urea derivative::suramin P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/jm020046y 10.7270/Q2VX0H71 12213051 Jacobson, KA; Jarvis, MF; Williams, M National Institute of Diabetes http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336799&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search SVR 5361 125086901 45906 CHEMBL265502 DB04786 1728 C07974 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50807028 CNc1ncnc2n(cnc12)[C@H]1C[C@H](OP(O)(O)=O)[C@@H](COP(O)(O)=O)O1 InChI=1S/C11H17N5O9P2/c1-12-10-9-11(14-4-13-10)16(5-15-9)8-2-6(25-27(20,21)22)7(24-8)3-23-26(17,18)19/h4-8H,2-3H2,1H3,(H,12,13,14)(H2,17,18,19)(H2,20,21,22)/t6-,7+,8+/m0/s1 CCPLITQNIFLYQB-XLPZGREQSA-N 50118229 CHEMBL129841::MRS 2179 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/jm020046y 10.7270/Q2VX0H71 12213051 Jacobson, KA; Jarvis, MF; Williams, M National Institute of Diabetes http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118229 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118229&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 5311303 104011566 CHEMBL129841 ZINC03985980 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50807029 Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O InChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1 ZKHQWZAMYRWXGA-KQYNXXCUSA-N 50366480 ADENOSINE TRIPHOSPHATE::ATP P2Y purinoceptor 4 Homo sapiens 43000 ChEMBL 10.1021/jm020046y 10.7270/Q2VX0H71 12213051 Jacobson, KA; Jarvis, MF; Williams, M National Institute of Diabetes http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366480&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search ATP 5957 160845582 15422 C03517 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50806945 Cc1nc(N=Nc2ccc(cc2S(O)(=O)=O)S(O)(=O)=O)c(COP(O)(O)=O)c(C=O)c1O InChI=1S/C14H14N3O12PS2/c1-7-13(19)9(5-18)10(6-29-30(20,21)22)14(15-7)17-16-11-3-2-8(31(23,24)25)4-12(11)32(26,27)28/h2-5,19H,6H2,1H3,(H2,20,21,22)(H,23,24,25)(H,26,27,28) PNFZSRRRZNXSMF-UHFFFAOYSA-N 85043 CAS_149017-66-3::CHEMBL69234::NSC_6093163::PPADS P2Y purinoceptor 4 Homo sapiens >10000 ChEMBL 10.1021/jm020046y 10.7270/Q2VX0H71 12213051 Jacobson, KA; Jarvis, MF; Williams, M National Institute of Diabetes http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85043&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 5478935 136351143 CHEMBL69234 ZINC18247107 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50850037 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)n1ccc2ccc(Cl)cc2c1=O InChI=1S/C14H17ClNO14P3/c15-8-2-1-7-3-4-16(13(19)9(7)5-8)14-12(18)11(17)10(28-14)6-27-32(23,24)30-33(25,26)29-31(20,21)22/h1-5,10-12,14,17-18H,6H2,(H,23,24)(H,25,26)(H2,20,21,22)/t10-,11-,12-,14-/m1/s1 OIBMBKVCJFCFMA-HKUMRIAESA-N 50195828 ({[({[(2R,3S,4R,5R)-5-(7-chloro-1-oxo-1,2-dihydroisoquinolin-2-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid::CHEMBL240201 P2Y purinoceptor 4 Homo sapiens 20000 ChEMBL 10.1016/j.bmcl.2006.09.017 10.7270/Q2CC11JS 17011188 Brookings, D; Davenport, RJ; Davis, J; Galvin, FC; Lloyd, S; Mack, SR; Owens, R; Sabin, V; Wynn, J UCB-Group http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50195828 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50195828&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44439758 104077776 CHEMBL240201 C03517 ZINC14165117 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50850046 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)n1ccc2ccc(F)cc2c1=O InChI=1S/C14H17FNO14P3/c15-8-2-1-7-3-4-16(13(19)9(7)5-8)14-12(18)11(17)10(28-14)6-27-32(23,24)30-33(25,26)29-31(20,21)22/h1-5,10-12,14,17-18H,6H2,(H,23,24)(H,25,26)(H2,20,21,22)/t10-,11-,12-,14-/m1/s1 PWMTWCIWTNGYAD-HKUMRIAESA-N 50195825 ({[({[(2R,3S,4R,5R)-5-(7-fluoro-1-oxo-1,2-dihydroisoquinolin-2-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid::CHEMBL399017 P2Y purinoceptor 4 Homo sapiens 3583 ChEMBL 10.1016/j.bmcl.2006.09.017 10.7270/Q2CC11JS 17011188 Brookings, D; Davenport, RJ; Davis, J; Galvin, FC; Lloyd, S; Mack, SR; Owens, R; Sabin, V; Wynn, J UCB-Group http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50195825 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50195825&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44439757 104077773 CHEMBL399017 C03517 ZINC14165173 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50850048 CSc1cc2ccn([C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)c(=O)c2cc1F InChI=1S/C15H19FNO14P3S/c1-35-11-4-7-2-3-17(14(20)8(7)5-9(11)16)15-13(19)12(18)10(29-15)6-28-33(24,25)31-34(26,27)30-32(21,22)23/h2-5,10,12-13,15,18-19H,6H2,1H3,(H,24,25)(H,26,27)(H2,21,22,23)/t10-,12-,13-,15-/m1/s1 PIOIJNXBHLURIU-BPGGGUHBSA-N 50195835 ({[({[(2R,3S,4R,5R)-5-[7-fluoro-6-(methylsulfanyl)-1-oxo-1,2-dihydroisoquinolin-2-yl]-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid::CHEMBL427685 P2Y purinoceptor 4 Homo sapiens >20000 ChEMBL 10.1016/j.bmcl.2006.09.017 10.7270/Q2CC11JS 17011188 Brookings, D; Davenport, RJ; Davis, J; Galvin, FC; Lloyd, S; Mack, SR; Owens, R; Sabin, V; Wynn, J UCB-Group http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50195835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50195835&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 16216480 104077783 CHEMBL427685 C03517 ZINC14165197 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50850049 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)n1ccc2ccccc2c1=O InChI=1S/C14H18NO14P3/c16-11-10(7-26-31(22,23)29-32(24,25)28-30(19,20)21)27-14(12(11)17)15-6-5-8-3-1-2-4-9(8)13(15)18/h1-6,10-12,14,16-17H,7H2,(H,22,23)(H,24,25)(H2,19,20,21)/t10-,11-,12-,14-/m1/s1 VNYFQXUDSXOXNV-HKUMRIAESA-N 50195826 ({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(1-oxo-1,2-dihydroisoquinolin-2-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid::CHEMBL393100 P2Y purinoceptor 4 Homo sapiens 7043 ChEMBL 10.1016/j.bmcl.2006.09.017 10.7270/Q2CC11JS 17011188 Brookings, D; Davenport, RJ; Davis, J; Galvin, FC; Lloyd, S; Mack, SR; Owens, R; Sabin, V; Wynn, J UCB-Group http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50195826 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50195826&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44439743 104077774 CHEMBL393100 C03517 ZINC14165100 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50850060 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)n1ccc2cc(F)c(F)cc2c1=O InChI=1S/C14H16F2NO14P3/c15-8-3-6-1-2-17(13(20)7(6)4-9(8)16)14-12(19)11(18)10(29-14)5-28-33(24,25)31-34(26,27)30-32(21,22)23/h1-4,10-12,14,18-19H,5H2,(H,24,25)(H,26,27)(H2,21,22,23)/t10-,11-,12-,14-/m1/s1 UVFKSFDIWKHRJL-HKUMRIAESA-N 50195822 ({[({[(2R,3S,4R,5R)-5-(6,7-difluoro-1-oxo-1,2-dihydroisoquinolin-2-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid::CHEMBL391663 P2Y purinoceptor 4 Homo sapiens >20000 ChEMBL 10.1016/j.bmcl.2006.09.017 10.7270/Q2CC11JS 17011188 Brookings, D; Davenport, RJ; Davis, J; Galvin, FC; Lloyd, S; Mack, SR; Owens, R; Sabin, V; Wynn, J UCB-Group http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50195822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50195822&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44439765 104077770 CHEMBL391663 C03517 ZINC44086874 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50850155 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)c1nc2cc(ccc2s1)C(F)(F)F InChI=1S/C13H15F3NO13P3S/c14-13(15,16)5-1-2-8-6(3-5)17-12(34-8)11-10(19)9(18)7(28-11)4-27-32(23,24)30-33(25,26)29-31(20,21)22/h1-3,7,9-11,18-19H,4H2,(H,23,24)(H,25,26)(H2,20,21,22)/t7-,9-,10-,11-/m1/s1 JWOOVSDBHPDOSN-QCNRFFRDSA-N 50197696 ({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid::CHEMBL391317 P2Y purinoceptor 4 Homo sapiens >20000 ChEMBL 10.1016/j.bmcl.2006.10.038 10.7270/Q2QN67MX 17079144 Davenport, RJ; Diaz, P; Galvin, FC; Lloyd, S; Mack, SR; Owens, R; Sabin, V; Wynn, J UCB-Group http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197696 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197696&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 10168108 104078956 CHEMBL391317 C03517 ZINC44086673 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50850162 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)c1nc2c(F)cc(Cl)cc2s1 InChI=1S/C12H14ClFNO13P3S/c13-4-1-5(14)8-7(2-4)32-12(15-8)11-10(17)9(16)6(26-11)3-25-30(21,22)28-31(23,24)27-29(18,19)20/h1-2,6,9-11,16-17H,3H2,(H,21,22)(H,23,24)(H2,18,19,20)/t6-,9-,10-,11-/m1/s1 NZDFJQYCJSIIQR-FOBYXSAKSA-N 50197694 ({[({[(2R,3S,4R,5R)-5-(6-chloro-4-fluoro-1,3-benzothiazol-2-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid::CHEMBL392989 P2Y purinoceptor 4 Homo sapiens 4233 ChEMBL 10.1016/j.bmcl.2006.10.038 10.7270/Q2QN67MX 17079144 Davenport, RJ; Diaz, P; Galvin, FC; Lloyd, S; Mack, SR; Owens, R; Sabin, V; Wynn, J UCB-Group http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197694 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197694&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 10191162 104078954 CHEMBL392989 C03517 ZINC44086590 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50850167 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)c1nc2ccccc2s1 InChI=1S/C12H16NO13P3S/c14-9-7(5-23-28(19,20)26-29(21,22)25-27(16,17)18)24-11(10(9)15)12-13-6-3-1-2-4-8(6)30-12/h1-4,7,9-11,14-15H,5H2,(H,19,20)(H,21,22)(H2,16,17,18)/t7-,9-,10-,11-/m1/s1 CIAGCYTVMPWBBD-QCNRFFRDSA-N 50197697 ({[({[(2R,3S,4R,5R)-5-(1,3-benzothiazol-2-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid::CHEMBL241481 P2Y purinoceptor 4 Homo sapiens 4121 ChEMBL 10.1016/j.bmcl.2006.10.038 10.7270/Q2QN67MX 17079144 Davenport, RJ; Diaz, P; Galvin, FC; Lloyd, S; Mack, SR; Owens, R; Sabin, V; Wynn, J UCB-Group http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197697 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197697&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 10303040 104078957 CHEMBL241481 C03517 ZINC38475908 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50840452 O[C@@H]1C[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]1n1ccc(=O)[nH]c1=O InChI=1S/C9H14N2O11P2/c12-6-3-5(4-20-24(18,19)22-23(15,16)17)21-8(6)11-2-1-7(13)10-9(11)14/h1-2,5-6,8,12H,3-4H2,(H,18,19)(H,10,13,14)(H2,15,16,17)/t5-,6+,8+/m0/s1 LVHDDSZQFIKYOE-SHYZEUOFSA-N 50194161 (2R,3R,5S)-1-(5-(diphosphoryloxymethyl)-3-hydroxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione triethylammonium salt P2Y purinoceptor 4 Homo sapiens 3100 ChEMBL 10.1021/jm060485n 10.7270/Q2ZC83NW 16942026 Besada, P; Shin, DH; Costanzi, S; Ko, H; Mathe, C; Gagneron, J; Gosselin, G; Maddileti, S; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50194161 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50194161&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 15485121 104076492 C03517 ZINC34569913 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50855172 COc1ccccc1Nc1cc(c(N)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C21H16N2O6S/c1-29-15-9-5-4-8-13(15)23-14-10-16(30(26,27)28)19(22)18-17(14)20(24)11-6-2-3-7-12(11)21(18)25/h2-10,23H,22H2,1H3,(H,26,27,28)/p-1 WCRXWKFBJBYISN-UHFFFAOYSA-M 50336767 CHEMBL257495::PSB-716::sodium 1-amino-4-(2-methoxyphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 50000 ChEMBL 10.1016/j.bmcl.2007.10.082 10.7270/Q2RX9CXT 18006312 Weyler, S; Baqi, Y; Hillmann, P; Kaulich, M; Hunder, AM; Muller, IA; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336767 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336767&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 59448190 125086869 CHEMBL257495 ZINC29130857 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50840834 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(O)=O)n1cc(Br)c(=O)[nH]c1=O InChI=1S/C9H13BrN2O12P2/c10-3-1-12(9(16)11-7(3)15)8-6(14)5(13)4(23-8)2-22-26(20,21)24-25(17,18)19/h1,4-6,8,13-14H,2H2,(H,20,21)(H,11,15,16)(H2,17,18,19)/t4-,5-,6-,8-/m1/s1 LEODOYNQKMXKRC-UAKXSSHOSA-N 50199173 ((2R,3S,4R,5R)-5-(5-bromo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl trihydrogen diphosphate::5-bromo-1-beta-D-ribofuranosyl(3H)pyrimidine-2,4-dione 5'-diphosphate::CHEMBL214698 P2Y purinoceptor 4 Homo sapiens 7200 ChEMBL 10.1021/jm060848j 10.7270/Q2SN09RW 17125260 El-Tayeb, A; Qi, A; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199173&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 23379800 104079837 CHEMBL214698 C03517 ZINC38149753 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50840839 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(O)=O)n1ccc(=O)[nH]c1=S InChI=1S/C9H13N2O8PS/c12-5-1-2-11(9(21)10-5)8-7(14)6(13)4(19-8)3-18-20(15,16)17/h1-2,4,6-8,13-14H,3H2,(H,10,12,21)(H2,15,16,17)/t4-,6-,7-,8-/m1/s1 OEUXFECIJDETRF-XVFCMESISA-N 50199180 1-(BETA-D-RIBOFURANOSYL)-2-THIO-URACIL-5'-PHOSPHATE::2-thio-1-beta-D-ribofuranosyl(3H)pyrimidine-2,4-dione 5'-monophosphate::CHEMBL384771 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/jm060848j 10.7270/Q2SN09RW 17125260 El-Tayeb, A; Qi, A; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199180 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199180&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search SUR 3081495 104079844 CHEMBL384771 ZINC13517211 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50840841 O[C@@H]1[C@@H](COP(O)(O)=O)O[C@H]([C@@H]1O)n1c(O)cc(=O)[nH]c1=O InChI=1S/C9H13N2O10P/c12-4-1-5(13)11(9(16)10-4)8-7(15)6(14)3(21-8)2-20-22(17,18)19/h1,3,6-8,13-15H,2H2,(H,10,12,16)(H2,17,18,19)/t3-,6-,7-,8-/m1/s1 UDOBICLZEKUKCV-YXZULKJRSA-N 50199178 1-beta-D-ribofuranosyl(3H)pyrimidine-2,4,6-trione 5'-monophosphate::3,4-dihydroxy-5-(6-oxido-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl phosphate::6-HYDROXYURIDINE-5'-PHOSPHATE::6-hydroxy-UMP::CHEMBL383923 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/jm060848j 10.7270/Q2SN09RW 17125260 El-Tayeb, A; Qi, A; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199178 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199178&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search BMP 161647 104079842 CHEMBL383923 ZINC24479522 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50840843 Cn1c(=O)ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c1=O InChI=1S/C10H17N2O15P3/c1-11-6(13)2-3-12(10(11)16)9-8(15)7(14)5(25-9)4-24-29(20,21)27-30(22,23)26-28(17,18)19/h2-3,5,7-9,14-15H,4H2,1H3,(H,20,21)(H,22,23)(H2,17,18,19)/t5-,7-,8-,9-/m1/s1 JHGDTDPUVDFPIL-ZOQUXTDFSA-N 50199183 3-methyl-1-beta-D-ribofuranosylpyrimidine-2,4-dione 5'-triphosphate::CHEMBL215783 P2Y purinoceptor 4 Homo sapiens 2920 ChEMBL 10.1021/jm060848j 10.7270/Q2SN09RW 17125260 El-Tayeb, A; Qi, A; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199183 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199183&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44417696 104079847 CHEMBL215783 C03517 ZINC38149755 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50840847 CCCc1cc(=O)n([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@H]3OP(O)(=O)O[C@@H]23)c(=O)[nH]1 InChI=1S/C12H20N2O17P4/c1-2-3-6-4-8(15)14(12(16)13-6)11-10-9(28-34(22,23)29-10)7(27-11)5-26-33(20,21)31-35(24,25)30-32(17,18)19/h4,7,9-11H,2-3,5H2,1H3,(H,13,16)(H,20,21)(H,22,23)(H,24,25)(H2,17,18,19)/t7-,9-,10-,11-/m1/s1 TVHZXCKQSILXQE-QCNRFFRDSA-N 50199187 6-propyl-3-beta-D-ribofuranosyl(1H)pyrimidine-2,4-dione 2',3'-(cyclic phosphate) 5'-triphosphate::CHEMBL217370 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/jm060848j 10.7270/Q2SN09RW 17125260 El-Tayeb, A; Qi, A; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199187 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199187&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 11994005 104079851 CHEMBL217370 C03517 ZINC43543903 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50840851 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)n1ccc(=O)n(CC(=O)c2ccccc2)c1=O InChI=1S/C17H21N2O16P3/c20-11(10-4-2-1-3-5-10)8-19-13(21)6-7-18(17(19)24)16-15(23)14(22)12(33-16)9-32-37(28,29)35-38(30,31)34-36(25,26)27/h1-7,12,14-16,22-23H,8-9H2,(H,28,29)(H,30,31)(H2,25,26,27)/t12-,14-,15-,16-/m1/s1 BTNPGBJHKRUBLX-DTZQCDIJSA-N 50199177 3-phenacyl-1-beta-D-ribofuranosylpyrimidine-2,4-dione 5'-triphosphate::CHEMBL385488 P2Y purinoceptor 4 Homo sapiens >1000 ChEMBL 10.1021/jm060848j 10.7270/Q2SN09RW 17125260 El-Tayeb, A; Qi, A; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199177 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199177&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 11994007 104079841 CHEMBL385488 C03517 ZINC44069179 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50840854 Cc1cc(=O)n([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)[nH]1 InChI=1S/C10H17N2O15P3/c1-4-2-6(13)12(10(16)11-4)9-8(15)7(14)5(25-9)3-24-29(20,21)27-30(22,23)26-28(17,18)19/h2,5,7-9,14-15H,3H2,1H3,(H,11,16)(H,20,21)(H,22,23)(H2,17,18,19)/t5-,7-,8-,9-/m1/s1 AROARRWARGPJJC-ZOQUXTDFSA-N 50199189 6-methyl-3-beta-D-ribofuranosyl(1H)pyrimidine-2,4-dione 5'-triphosphate::CHEMBL413841 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/jm060848j 10.7270/Q2SN09RW 17125260 El-Tayeb, A; Qi, A; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199189 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199189&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 11994009 104079853 CHEMBL413841 C03517 ZINC40791377 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50840855 Cc1cc(=O)n([C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)[nH]1 InChI=1S/C10H16N2O12P2/c1-4-2-6(13)12(10(16)11-4)9-8(15)7(14)5(23-9)3-22-26(20,21)24-25(17,18)19/h2,5,7-9,14-15H,3H2,1H3,(H,11,16)(H,20,21)(H2,17,18,19)/t5-,7-,8-,9-/m1/s1 AZLXOEYOOFJHLI-ZOQUXTDFSA-N 50199175 6-methyl-3-beta-D-ribofuranosyl(1H)pyrimidine-2,4-dione 5'-diphosphate::CHEMBL386096 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/jm060848j 10.7270/Q2SN09RW 17125260 El-Tayeb, A; Qi, A; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199175 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199175&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 11993883 104079839 CHEMBL386096 C03517 ZINC40766689 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50840857 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)C(Cl)(Cl)P(O)(O)=O)n1cc(Br)c(=O)[nH]c1=O InChI=1S/C10H14BrCl2N2O14P3/c11-3-1-15(9(19)14-7(3)18)8-6(17)5(16)4(28-8)2-27-32(25,26)29-31(23,24)10(12,13)30(20,21)22/h1,4-6,8,16-17H,2H2,(H,23,24)(H,25,26)(H,14,18,19)(H2,20,21,22)/t4-,5-,6-,8-/m1/s1 KMOKHPPESJJVPB-UAKXSSHOSA-N 50199186 5-bromouridine-5'-uridylic acid (1,1-dichloro-1-phosphonomethyl-1-phosphonyl)anhydride::CHEMBL217467 P2Y purinoceptor 4 Homo sapiens 3990 ChEMBL 10.1021/jm060848j 10.7270/Q2SN09RW 17125260 El-Tayeb, A; Qi, A; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199186 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199186&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 11993891 104079850 CHEMBL217467 ZINC49942323 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50840859 CCCc1cc(=O)n([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)[nH]1 InChI=1S/C12H21N2O15P3/c1-2-3-6-4-8(15)14(12(18)13-6)11-10(17)9(16)7(27-11)5-26-31(22,23)29-32(24,25)28-30(19,20)21/h4,7,9-11,16-17H,2-3,5H2,1H3,(H,13,18)(H,22,23)(H,24,25)(H2,19,20,21)/t7-,9-,10-,11-/m1/s1 NHAYKDHIHBRAHL-QCNRFFRDSA-N 50199172 6-propyl-3-beta-D-ribofuranosyl(1H)pyrimidine-2,4-dione 5'-triphosphate::CHEMBL425805 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/jm060848j 10.7270/Q2SN09RW 17125260 El-Tayeb, A; Qi, A; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199172 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199172&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 11995643 104079836 CHEMBL425805 C03517 ZINC44220619 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50840868 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1c(O)cc(=O)[nH]c1=O InChI=1S/C9H15N2O16P3/c12-4-1-5(13)11(9(16)10-4)8-7(15)6(14)3(25-8)2-24-29(20,21)27-30(22,23)26-28(17,18)19/h1,3,6-8,13-15H,2H2,(H,20,21)(H,22,23)(H,10,12,16)(H2,17,18,19)/t3-,6-,7-,8-/m1/s1 MTOPXBLKWYGUFG-YXZULKJRSA-N 50199188 1-beta-D-ribofuranosyl(3H)pyrimidine-2,4,6-trione 5'-triphosphate::CHEMBL436959 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/jm060848j 10.7270/Q2SN09RW 17125260 El-Tayeb, A; Qi, A; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199188 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199188&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 11995641 104079852 CHEMBL436959 C03517 ZINC40818464 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50840869 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)n1cc(Br)c(=O)[nH]c1=O InChI=1S/C9H14BrN2O15P3/c10-3-1-12(9(16)11-7(3)15)8-6(14)5(13)4(25-8)2-24-29(20,21)27-30(22,23)26-28(17,18)19/h1,4-6,8,13-14H,2H2,(H,20,21)(H,22,23)(H,11,15,16)(H2,17,18,19)/t4-,5-,6-,8-/m1/s1 IWFHOSULCAJGRM-UAKXSSHOSA-N 50199192 ((2R,3S,4R,5R)-5-(5-bromo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate::5-bromo-1-beta-D-ribofuranosyl(3H)pyrimidine-2,4-dione 5'-triphosphate::5-bromo-UTP::CHEMBL384527 P2Y purinoceptor 4 Homo sapiens 3460 ChEMBL 10.1021/jm060848j 10.7270/Q2SN09RW 17125260 El-Tayeb, A; Qi, A; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199192 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199192&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search BUP 9872620 104079856 CHEMBL384527 C03517 ZINC38149754 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50840870 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(O)=O)n1ccc(=O)n(CC(=O)c2ccccc2)c1=O InChI=1S/C17H20N2O13P2/c20-11(10-4-2-1-3-5-10)8-19-13(21)6-7-18(17(19)24)16-15(23)14(22)12(31-16)9-30-34(28,29)32-33(25,26)27/h1-7,12,14-16,22-23H,8-9H2,(H,28,29)(H2,25,26,27)/t12-,14-,15-,16-/m1/s1 SEUHNFHNNANEAJ-DTZQCDIJSA-N 50199191 ((2R,3S,4R,5R)-5-(2,4-dioxo-3-(2-oxo-2-phenylethyl)-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl trihydrogen diphosphate::3-phenacyl-1-beta-D-ribofuranosylpyrimidine-2,4-dione 5'-diphosphate::CHEMBL215294 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/jm060848j 10.7270/Q2SN09RW 17125260 El-Tayeb, A; Qi, A; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199191&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 11994011 104079855 CHEMBL215294 1745 C03517 ZINC38149756 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50840871 CCCc1cc(=O)n([C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)[nH]1 InChI=1S/C12H20N2O12P2/c1-2-3-6-4-8(15)14(12(18)13-6)11-10(17)9(16)7(25-11)5-24-28(22,23)26-27(19,20)21/h4,7,9-11,16-17H,2-3,5H2,1H3,(H,13,18)(H,22,23)(H2,19,20,21)/t7-,9-,10-,11-/m1/s1 LNRVNOYVTJQVGH-QCNRFFRDSA-N 50199181 6-propyl-3-beta-D-ribofuranosyl(1H)pyrimidine-2,4-dione 5'-diphosphate::CHEMBL385506 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/jm060848j 10.7270/Q2SN09RW 17125260 El-Tayeb, A; Qi, A; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199181&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 11994013 104079845 CHEMBL385506 C03517 ZINC40767062 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50840876 Cn1c(=O)ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c1=O InChI=1S/C10H16N2O12P2/c1-11-6(13)2-3-12(10(11)16)9-8(15)7(14)5(23-9)4-22-26(20,21)24-25(17,18)19/h2-3,5,7-9,14-15H,4H2,1H3,(H,20,21)(H2,17,18,19)/t5-,7-,8-,9-/m1/s1 YCOAHNQUHLQMSA-ZOQUXTDFSA-N 50194162 3-methyl-1-beta-D-ribofuranosylpyrimidine-2,4-dione 5'-diphosphate::CHEMBL215447::[(2R,3S,4R,5R)-3,4-dihydroxy-5-(3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methyl trihydrogen diphosphate P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/jm060848j 10.7270/Q2SN09RW 17125260 El-Tayeb, A; Qi, A; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50194162 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50194162&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44415751 104076493 CHEMBL215447 C03517 ZINC38149512 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50840878 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(O)=O)n1cc(Br)c(=O)[nH]c1=O InChI=1S/C9H12BrN2O9P/c10-3-1-12(9(16)11-7(3)15)8-6(14)5(13)4(21-8)2-20-22(17,18)19/h1,4-6,8,13-14H,2H2,(H,11,15,16)(H2,17,18,19)/t4-,5-,6-,8-/m1/s1 IDPVUMJNEZFMNU-UAKXSSHOSA-N 50199184 5-BROMO-URIDINE-5'-MONOPHOSPHATE::5-bromo-1-beta-D-ribofuranosyl(3H)pyrimidine-2,4-dione 5'-monophosphate::CHEMBL214830 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/jm060848j 10.7270/Q2SN09RW 17125260 El-Tayeb, A; Qi, A; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199184 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199184&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 5BU 150973 104079848 47131 CHEMBL214830 ZINC13518134 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50840879 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(O)=O)n1ccc(=O)[nH]c1=S InChI=1S/C9H14N2O11P2S/c12-5-1-2-11(9(25)10-5)8-7(14)6(13)4(21-8)3-20-24(18,19)22-23(15,16)17/h1-2,4,6-8,13-14H,3H2,(H,18,19)(H,10,12,25)(H2,15,16,17)/t4-,6-,7-,8-/m1/s1 BMJOHSBBMARQHC-XVFCMESISA-N 50194160 (2R,3R,4S,5R)-1-(3,4-dihydroxy-5-(diphosphoryloxymethyl)-tetrahydrofuran-2-yl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one ammonium salt::CHEMBL216011 P2Y purinoceptor 4 Homo sapiens >1000 ChEMBL 10.1021/jm060848j 10.7270/Q2SN09RW 17125260 El-Tayeb, A; Qi, A; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50194160 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50194160&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 16082712 104076491 CHEMBL216011 C03517 ZINC35033723 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50840883 Cn1c(=O)ccn([C@@H]2O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]2O)c1=O InChI=1S/C10H15N2O9P/c1-11-6(13)2-3-12(10(11)16)9-8(15)7(14)5(21-9)4-20-22(17,18)19/h2-3,5,7-9,14-15H,4H2,1H3,(H2,17,18,19)/t5-,7-,8-,9-/m1/s1 KZSHODFDDQCIMT-ZOQUXTDFSA-N 50199190 3-METHYLURIDINE-5'-MONOPHOSHATE::3-methyl-1-beta-D-ribofuranosyl-pyrimidine-2,4-dione 5'-monophosphate::CHEMBL215940 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/jm060848j 10.7270/Q2SN09RW 17125260 El-Tayeb, A; Qi, A; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199190&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 3MU 44602426 104079854 74773 CHEMBL215940 ZINC13517711 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50840889 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(O)=O)n1ccc(=O)n(CC(=O)c2ccccc2)c1=O InChI=1S/C17H19N2O10P/c20-11(10-4-2-1-3-5-10)8-19-13(21)6-7-18(17(19)24)16-15(23)14(22)12(29-16)9-28-30(25,26)27/h1-7,12,14-16,22-23H,8-9H2,(H2,25,26,27)/t12-,14-,15-,16-/m1/s1 BVOHBCXZDSIVFU-DTZQCDIJSA-N 50199174 3-phenacyl-1-beta-D-ribofuranosylpyrimidine-2,4-dione 5'-monophosphate::CHEMBL215381 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/jm060848j 10.7270/Q2SN09RW 17125260 El-Tayeb, A; Qi, A; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199174 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199174&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 11993885 104079838 CHEMBL215381 ZINC40568302 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50840890 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1OP(O)(O)=O)n1ccc(=O)n(CC(=O)c2ccccc2)c1=O InChI=1S/C17H22N2O19P4/c20-11(10-4-2-1-3-5-10)8-19-13(21)6-7-18(17(19)23)16-15(36-39(24,25)26)14(22)12(35-16)9-34-41(30,31)38-42(32,33)37-40(27,28)29/h1-7,12,14-16,22H,8-9H2,(H,30,31)(H,32,33)(H2,24,25,26)(H2,27,28,29)/t12-,14-,15-,16-/m1/s1 QTOAFQFXYVDFKV-DTZQCDIJSA-N 50199193 3-phenacyl-1-beta-D-ribofuranosylpyrimidine-2,4-dione 2'-Monophosphate-5'-triphosphate::CHEMBL265170 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/jm060848j 10.7270/Q2SN09RW 17125260 El-Tayeb, A; Qi, A; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199193 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199193&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 11993889 104079857 CHEMBL265170 C03517 ZINC49592701 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50840891 CCCc1cc(=O)n([C@@H]2O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)[nH]1 InChI=1S/C12H19N2O9P/c1-2-3-6-4-8(15)14(12(18)13-6)11-10(17)9(16)7(23-11)5-22-24(19,20)21/h4,7,9-11,16-17H,2-3,5H2,1H3,(H,13,18)(H2,19,20,21)/t7-,9-,10-,11-/m1/s1 XPXCQFUBYLUZRO-QCNRFFRDSA-N 50199182 6-propyl-3-beta-D-ribofuranosyl(1H)pyrimidine-2,4-dione 5'-monophosphate::CHEMBL217391 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/jm060848j 10.7270/Q2SN09RW 17125260 El-Tayeb, A; Qi, A; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199182 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199182&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 11993887 104079846 CHEMBL217391 ZINC40576003 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50840893 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)n1ccc(=O)[nH]c1=S InChI=1S/C9H15N2O14P3S/c12-5-1-2-11(9(29)10-5)8-7(14)6(13)4(23-8)3-22-27(18,19)25-28(20,21)24-26(15,16)17/h1-2,4,6-8,13-14H,3H2,(H,18,19)(H,20,21)(H,10,12,29)(H2,15,16,17)/t4-,6-,7-,8-/m1/s1 KHYOUGAATNYCAZ-XVFCMESISA-N 50199176 2-thio-1-beta-D-ribofuranosyl(3H)pyrimidine-2,4-dione 5'-triphosphate::CHEMBL217803 P2Y purinoceptor 4 Homo sapiens 1770 ChEMBL 10.1021/jm060848j 10.7270/Q2SN09RW 17125260 El-Tayeb, A; Qi, A; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199176&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 10174453 104079840 CHEMBL217803 C03517 ZINC13540486 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50840894 Cc1cc(=O)n([C@@H]2O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)[nH]1 InChI=1S/C10H15N2O9P/c1-4-2-6(13)12(10(16)11-4)9-8(15)7(14)5(21-9)3-20-22(17,18)19/h2,5,7-9,14-15H,3H2,1H3,(H,11,16)(H2,17,18,19)/t5-,7-,8-,9-/m1/s1 BBIBNZFXLBFONK-ZOQUXTDFSA-N 50199179 6-methyl-3-beta-D-ribofuranosyl(1H)pyrimidine-2,4-dione 5'-monophosphate::CHEMBL215263 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/jm060848j 10.7270/Q2SN09RW 17125260 El-Tayeb, A; Qi, A; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199179 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199179&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44417704 104079843 CHEMBL215263 ZINC40568209 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50843475 CC(C)(C)C(=O)N[C@@H]1[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1n1ccc(=O)[nH]c1=S InChI=1S/C14H24N3O14P3S/c1-14(2,3)12(20)16-9-10(19)7(29-11(9)17-5-4-8(18)15-13(17)35)6-28-33(24,25)31-34(26,27)30-32(21,22)23/h4-5,7,9-11,19H,6H2,1-3H3,(H,16,20)(H,24,25)(H,26,27)(H,15,18,35)(H2,21,22,23)/t7-,9-,10-,11-/m1/s1 YDDXXQBOCIZVFB-QCNRFFRDSA-N 50205408 2'-trifluoroacetylamino-2'-deoxy-2-thiouridine 5'-triphosphate::CHEMBL221162 P2Y purinoceptor 4 Homo sapiens 8300 ChEMBL 10.1021/jm060903o 10.7270/Q2PK0GZ1 17302398 Ivanov, AA; Ko, H; Cosyn, L; Maddileti, S; Besada, P; Fricks, I; Costanzi, S; Harden, TK; Calenbergh, SV; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50205408 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50205408&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44420650 104083756 CHEMBL221162 C03517 ZINC38151341 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50843477 N[C@@H]1[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1n1ccc(=O)[nH]c1=O InChI=1S/C9H16N3O14P3/c10-6-7(14)4(24-8(6)12-2-1-5(13)11-9(12)15)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,14H,3,10H2,(H,19,20)(H,21,22)(H,11,13,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1 RJZLOYMABJJGTA-XVFCMESISA-N 50205405 ({[({[(2R,3S,4R,5R)-4-amino-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid::CHEMBL385098 P2Y purinoceptor 4 Homo sapiens 1200 ChEMBL 10.1021/jm060903o 10.7270/Q2PK0GZ1 17302398 Ivanov, AA; Ko, H; Cosyn, L; Maddileti, S; Besada, P; Fricks, I; Costanzi, S; Harden, TK; Calenbergh, SV; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50205405 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50205405&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 11525909 104083753 CHEMBL385098 C03517 ZINC38151343 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50843485 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C18H26N4O23P4/c23-9-1-3-21(17(29)19-9)15-13(27)11(25)7(41-15)5-39-46(31,32)43-48(35,36)45-49(37,38)44-47(33,34)40-6-8-12(26)14(28)16(42-8)22-4-2-10(24)20-18(22)30/h1-4,7-8,11-16,25-28H,5-6H2,(H,31,32)(H,33,34)(H,35,36)(H,37,38)(H,19,23,29)(H,20,24,30)/t7-,8-,11-,12-,13-,14-,15-,16-/m1/s1 NMLMACJWHPHKGR-NCOIDOBVSA-N 50205413 CHEMBL221326::P(1),P(4)-bis(uridin-5'-yl) tetraphosphate::P1,P4-Bis(5'-uridyl) tetrahydrogen tetraphosphate P2Y purinoceptor 4 Homo sapiens 130 ChEMBL 10.1021/jm060903o 10.7270/Q2PK0GZ1 17302398 Ivanov, AA; Ko, H; Cosyn, L; Maddileti, S; Besada, P; Fricks, I; Costanzi, S; Harden, TK; Calenbergh, SV; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50205413 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50205413&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 148197 104083761 27791 CHEMBL221326 C06198 ZINC85433146 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50843486 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)n1ccc(=O)[nH]c1=S InChI=1S/C9H15N2O14P3S/c12-5-1-2-11(9(29)10-5)8-7(14)6(13)4(23-8)3-22-27(18,19)25-28(20,21)24-26(15,16)17/h1-2,4,6-8,13-14H,3H2,(H,18,19)(H,20,21)(H,10,12,29)(H2,15,16,17)/t4-,6-,7-,8-/m1/s1 KHYOUGAATNYCAZ-XVFCMESISA-N 50199176 2-thio-1-beta-D-ribofuranosyl(3H)pyrimidine-2,4-dione 5'-triphosphate::CHEMBL217803 P2Y purinoceptor 4 Homo sapiens 350 ChEMBL 10.1021/jm060903o 10.7270/Q2PK0GZ1 17302398 Ivanov, AA; Ko, H; Cosyn, L; Maddileti, S; Besada, P; Fricks, I; Costanzi, S; Harden, TK; Calenbergh, SV; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199176&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 10174453 104079840 CHEMBL217803 C03517 ZINC13540486 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50843496 Cc1cn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)[nH]c1=O InChI=1S/C10H17N2O15P3/c1-4-2-12(10(16)11-8(4)15)9-7(14)6(13)5(25-9)3-24-29(20,21)27-30(22,23)26-28(17,18)19/h2,5-7,9,13-14H,3H2,1H3,(H,20,21)(H,22,23)(H,11,15,16)(H2,17,18,19)/t5-,6-,7-,9-/m1/s1 RZCIEJXAILMSQK-JXOAFFINSA-N 50205415 ({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid::CHEMBL220940 P2Y purinoceptor 4 Homo sapiens 3900 ChEMBL 10.1021/jm060903o 10.7270/Q2PK0GZ1 17302398 Ivanov, AA; Ko, H; Cosyn, L; Maddileti, S; Besada, P; Fricks, I; Costanzi, S; Harden, TK; Calenbergh, SV; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50205415 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50205415&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 5T 451388 104083763 63550 CHEMBL220940 C03517 ZINC13519612 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50843502 N[C@@H]1[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1n1ccc(=O)[nH]c1=S InChI=1S/C9H16N3O13P3S/c10-6-7(14)4(23-8(6)12-2-1-5(13)11-9(12)29)3-22-27(18,19)25-28(20,21)24-26(15,16)17/h1-2,4,6-8,14H,3,10H2,(H,18,19)(H,20,21)(H,11,13,29)(H2,15,16,17)/t4-,6-,7-,8-/m1/s1 UWTUUIWWVPWHAA-XVFCMESISA-N 50205406 ((2R,3S,4R,5R)-4-amino-3-hydroxy-5-(4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate::2'-amino-2'-deoxy-2-thiouridine 5'-triphosphate::CHEMBL373780 P2Y purinoceptor 4 Homo sapiens 2400 ChEMBL 10.1021/jm060903o 10.7270/Q2PK0GZ1 17302398 Ivanov, AA; Ko, H; Cosyn, L; Maddileti, S; Besada, P; Fricks, I; Costanzi, S; Harden, TK; Calenbergh, SV; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50205406 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50205406&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 16116566 104083754 CHEMBL373780 1733 C03517 ZINC35276442 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50873351 Nc1c(cc(Nc2ccc(Nc3nc(Cl)nc(Nc4cccc(c4)S([O-])(=O)=O)n3)c(c2)S([O-])(=O)=O)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C29H20ClN7O11S3/c30-27-35-28(33-13-4-3-5-15(10-13)49(40,41)42)37-29(36-27)34-18-9-8-14(11-20(18)50(43,44)45)32-19-12-21(51(46,47)48)24(31)23-22(19)25(38)16-6-1-2-7-17(16)26(23)39/h1-12,32H,31H2,(H,40,41,42)(H,43,44,45)(H,46,47,48)(H2,33,34,35,36,37)/p-3 JQYMGXZJTCOARG-UHFFFAOYSA-K 50029031 1-Amino-4-{4-[4-chloro-6-(3-sulfo-phenylamino)-[1,3,5]triazin-2-ylamino]-3-sulfo-phenylamino}-9,10-dioxo-9,10-dihydro-anthracene-2-sulfonic acid1-Amino-4-{4-[4-chloro-6-(4-sulfo-phenylamino)-[1,3,5]triazin-2-ylamino]-3-sulfo-phenylamino}-9,10-dioxo-9,10-dihydro-anthracene-2-sulfonic acid::CHEMBL223344::CID44285648::basilen blue::cibacron blue (mixer, meta and para isomers P2Y purinoceptor 4 Homo sapiens 5750 ChEMBL 10.1021/jm800175e 10.7270/Q2XW4KQX 18630897 Brunschweiger, A; Iqbal, J; Umbach, F; Scheiff, AB; Munkonda, MN; Sevigny, J; Knowles, AF; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029031&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44285647 103938145 CHEMBL223344 C13746 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50873380 Cc1cc(N=Nc2ccc(cc2S([O-])(=O)=O)S([O-])(=O)=O)c(COP([O-])([O-])=O)c(C=O)c1O InChI=1S/C15H15N2O12PS2/c1-8-4-13(11(7-29-30(20,21)22)10(6-18)15(8)19)17-16-12-3-2-9(31(23,24)25)5-14(12)32(26,27)28/h2-6,19H,7H2,1H3,(H2,20,21,22)(H,23,24,25)(H,26,27,28)/p-4 FFLAALLXNFGXRL-UHFFFAOYSA-J 50262422 CHEMBL477339::sodium (E)-4-((3-formyl-4-hydroxy-5-methyl-2-(phosphonatooxymethyl)phenyl)diazenyl)benzene-1,3-disulfonate P2Y purinoceptor 4 Homo sapiens 73000 ChEMBL 10.1021/jm800175e 10.7270/Q2XW4KQX 18630897 Brunschweiger, A; Iqbal, J; Umbach, F; Scheiff, AB; Munkonda, MN; Sevigny, J; Knowles, AF; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50262422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50262422&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91935431 104111119 CHEMBL477339 ZINC40917879 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871772 Nc1nc2n(cnc2c(=O)[nH]1)[C@H]1C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)O1 InChI=1S/C19H27N7O21P4/c20-18-23-15-12(16(31)24-18)21-6-26(15)11-3-7(27)8(43-11)4-41-48(33,34)45-50(37,38)47-51(39,40)46-49(35,36)42-5-9-13(29)14(30)17(44-9)25-2-1-10(28)22-19(25)32/h1-2,6-9,11,13-14,17,27,29-30H,3-5H2,(H,33,34)(H,35,36)(H,37,38)(H,39,40)(H,22,28,32)(H3,20,23,24,31)/t7-,8+,9+,11+,13+,14+,17+/m0/s1 FZOKIFDNPVZUQG-DBBURVGMSA-N 50270555 CHEMBL505403::{[(2R,3S,5R)-5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy}({[({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy})phosphinic acid P2Y purinoceptor 4 Homo sapiens 540 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270555 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270555&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 10190954 104115726 CHEMBL505403 ZINC95535687 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871773 Nc1ccn([C@H]2C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n3ccc(=O)[nH]c3=S)O2)c(=O)n1 InChI=1S/C18H27N5O20P4S/c19-11-1-3-22(17(28)20-11)13-5-8(24)9(39-13)6-37-44(29,30)41-46(33,34)43-47(35,36)42-45(31,32)38-7-10-14(26)15(27)16(40-10)23-4-2-12(25)21-18(23)48/h1-4,8-10,13-16,24,26-27H,5-7H2,(H,29,30)(H,31,32)(H,33,34)(H,35,36)(H2,19,20,28)(H,21,25,48)/t8-,9+,10+,13+,14+,15+,16+/m0/s1 FYCRPTCGPHMUOQ-MIYUEGBISA-N 50270554 CHEMBL509434::P1-(2-thiouridine 5'-)-P4-(2'-deoxycytidine 5'-)tetraphosphate P2Y purinoceptor 4 Homo sapiens 710 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270554 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270554&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 24857827 104115725 CHEMBL509434 ZINC95616053 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871774 Nc1ccn([C@H]2C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n3ccc(=O)[nH]c3=O)O2)c(=O)n1 InChI=1S/C18H27N5O21P4/c19-11-1-3-22(17(28)20-11)13-5-8(24)9(40-13)6-38-45(30,31)42-47(34,35)44-48(36,37)43-46(32,33)39-7-10-14(26)15(27)16(41-10)23-4-2-12(25)21-18(23)29/h1-4,8-10,13-16,24,26-27H,5-7H2,(H,30,31)(H,32,33)(H,34,35)(H,36,37)(H2,19,20,28)(H,21,25,29)/t8-,9+,10+,13+,14+,15+,16+/m0/s1 FPNPSEMJLALQSA-MIYUEGBISA-N 50270553 CHEMBL507282::INS-37217::INS37217 P2Y purinoceptor 4 Homo sapiens 140 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270553 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270553&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 9875516 104115724 CHEMBL507282 ZINC85540154 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871775 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)C(F)(F)P(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O)n1ccc(=O)[nH]c1=O InChI=1S/C19H26F2N4O22P4/c20-19(21,48(34,35)46-50(38,39)42-5-7-11(28)13(30)15(44-7)24-3-1-9(26)22-17(24)32)49(36,37)47-51(40,41)43-6-8-12(29)14(31)16(45-8)25-4-2-10(27)23-18(25)33/h1-4,7-8,11-16,28-31H,5-6H2,(H,34,35)(H,36,37)(H,38,39)(H,40,41)(H,22,26,32)(H,23,27,33)/t7-,8-,11-,12-,13-,14-,15-,16-/m1/s1 YQQXUGVEZWDLKO-NCOIDOBVSA-N 50270551 CHEMBL502712::P1,P4-di(uridine 5'-)beta,gamma-difluoromethylenetetraphosphate P2Y purinoceptor 4 Homo sapiens >10000 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270551&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 10234467 104115722 CHEMBL502712 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871776 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=S)[nH]c1=O)n1ccc(=S)[nH]c1=O InChI=1S/C18H26N4O21P4S2/c23-11-7(39-15(13(11)25)21-3-1-9(48)19-17(21)27)5-37-44(29,30)41-46(33,34)43-47(35,36)42-45(31,32)38-6-8-12(24)14(26)16(40-8)22-4-2-10(49)20-18(22)28/h1-4,7-8,11-16,23-26H,5-6H2,(H,29,30)(H,31,32)(H,33,34)(H,35,36)(H,19,27,48)(H,20,28,49)/t7-,8-,11-,12-,13-,14-,15-,16-/m1/s1 HIKNCKKYLUUROS-NCOIDOBVSA-N 50270550 CHEMBL503798::{[(2R,3S,4R,5R)-3,4-dihydroxy-5-(2-oxo-4-sulfanylidene-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}({[({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(2-oxo-4-sulfanylidene-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy})phosphinic acid P2Y purinoceptor 4 Homo sapiens 80 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270550 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270550&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 9853990 104115721 CHEMBL503798 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871777 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C18H26N4O23P4/c23-9-1-3-21(17(29)19-9)15-13(27)11(25)7(41-15)5-39-46(31,32)43-48(35,36)45-49(37,38)44-47(33,34)40-6-8-12(26)14(28)16(42-8)22-4-2-10(24)20-18(22)30/h1-4,7-8,11-16,25-28H,5-6H2,(H,31,32)(H,33,34)(H,35,36)(H,37,38)(H,19,23,29)(H,20,24,30)/t7-,8-,11-,12-,13-,14-,15-,16-/m1/s1 NMLMACJWHPHKGR-NCOIDOBVSA-N 50205413 CHEMBL221326::P(1),P(4)-bis(uridin-5'-yl) tetraphosphate::P1,P4-Bis(5'-uridyl) tetrahydrogen tetraphosphate P2Y purinoceptor 4 Homo sapiens 130 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50205413 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50205413&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 148197 104083761 27791 CHEMBL221326 C06198 ZINC85433146 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871778 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C18H25N4O20P3/c23-9-1-3-21(17(29)19-9)15-13(27)11(25)7(39-15)5-37-43(31,32)41-45(35,36)42-44(33,34)38-6-8-12(26)14(28)16(40-8)22-4-2-10(24)20-18(22)30/h1-4,7-8,11-16,25-28H,5-6H2,(H,31,32)(H,33,34)(H,35,36)(H,19,23,29)(H,20,24,30)/t7-,8-,11-,12-,13-,14-,15-,16-/m1/s1 JPNWHMPVXHYIKN-NCOIDOBVSA-N 50241299 CHEMBL239151::{[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphinic acid P2Y purinoceptor 4 Homo sapiens 870 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241299&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 9875011 104098700 CHEMBL239151 ZINC49946842 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871779 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2OC(O)C[C@@H](O)[C@@H]2O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C15H26N2O22P4/c18-6-3-10(20)35-7(11(6)21)4-33-40(25,26)37-42(29,30)39-43(31,32)38-41(27,28)34-5-8-12(22)13(23)14(36-8)17-2-1-9(19)16-15(17)24/h1-2,6-8,10-14,18,20-23H,3-5H2,(H,25,26)(H,27,28)(H,29,30)(H,31,32)(H,16,19,24)/t6-,7-,8-,10?,11+,12-,13-,14-/m1/s1 HBRQZJDFQWHINU-SELJRJPRSA-N 50270548 CHEMBL454230::Uridine-5'-(2'-deoxy-glucose)-6'-tetraphosphate P2Y purinoceptor 4 Homo sapiens 4320 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270548 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270548&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44585521 104115719 CHEMBL454230 ZINC49841423 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871780 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2OC(O)[C@@H](O)[C@@H](O)[C@@H]2O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C15H26N2O23P4/c18-7-1-2-17(15(25)16-7)13-11(22)9(20)5(36-13)3-34-41(26,27)38-43(30,31)40-44(32,33)39-42(28,29)35-4-6-8(19)10(21)12(23)14(24)37-6/h1-2,5-6,8-14,19-24H,3-4H2,(H,26,27)(H,28,29)(H,30,31)(H,32,33)(H,16,18,25)/t5-,6-,8-,9-,10+,11-,12+,13-,14?/m1/s1 RZHCKCCBWWACOW-BHARQNLVSA-N 50270547 CHEMBL508122::Uridine-5'-mannose-6'-tetraphosphate P2Y purinoceptor 4 Homo sapiens >10000 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270547 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270547&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44585520 104115718 CHEMBL508122 ZINC95615794 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871781 OC[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H](O)[C@H]1O InChI=1S/C15H26N2O23P4/c18-3-5-8(20)10(22)12(24)14(36-5)37-42(28,29)39-44(32,33)40-43(30,31)38-41(26,27)34-4-6-9(21)11(23)13(35-6)17-2-1-7(19)16-15(17)25/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,30,31)(H,32,33)(H,16,19,25)/t5-,6-,8+,9-,10+,11-,12-,13-,14-/m1/s1 AJLLTXOUJGYGAA-ABVWGUQPSA-N 50270546 CHEMBL444212::Uridine-5'-galactose-1'-tetraphosphate P2Y purinoceptor 4 Homo sapiens 1770 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270546 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270546&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44585519 104115717 CHEMBL444212 ZINC95614922 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871782 OC[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H](O)[C@@H]1O InChI=1S/C15H26N2O23P4/c18-3-5-8(20)10(22)12(24)14(36-5)37-42(28,29)39-44(32,33)40-43(30,31)38-41(26,27)34-4-6-9(21)11(23)13(35-6)17-2-1-7(19)16-15(17)25/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,30,31)(H,32,33)(H,16,19,25)/t5-,6-,8-,9-,10+,11-,12-,13-,14-/m1/s1 AJLLTXOUJGYGAA-JZMIEXBBSA-N 50270545 CHEMBL499138::Uridine-5'-glucose-1'-tetraphosphate P2Y purinoceptor 4 Homo sapiens 2060 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270545 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270545&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44585518 104115716 CHEMBL499138 C01140 ZINC95540729 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871783 CC[C@]1(O)O[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@H](O)[C@H]1O InChI=1S/C16H28N2O22P4/c1-2-16(25)13(23)11(21)8(37-16)6-35-42(28,29)39-44(32,33)40-43(30,31)38-41(26,27)34-5-7-10(20)12(22)14(36-7)18-4-3-9(19)17-15(18)24/h3-4,7-8,10-14,20-23,25H,2,5-6H2,1H3,(H,26,27)(H,28,29)(H,30,31)(H,32,33)(H,17,19,24)/t7-,8+,10-,11+,12-,13-,14-,16+/m1/s1 IRHOAYPWMKMNPQ-MLTZJJJHSA-N 50270544 CHEMBL500840::Uridine-5'-fructose-6'-tetraphosphate P2Y purinoceptor 4 Homo sapiens 6300 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270544 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270544&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44585517 104115715 CHEMBL500840 ZINC95615718 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871784 N[C@@H]1[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1n1ccc(=O)[nH]c1=S InChI=1S/C9H16N3O13P3S/c10-6-7(14)4(23-8(6)12-2-1-5(13)11-9(12)29)3-22-27(18,19)25-28(20,21)24-26(15,16)17/h1-2,4,6-8,14H,3,10H2,(H,18,19)(H,20,21)(H,11,13,29)(H2,15,16,17)/t4-,6-,7-,8-/m1/s1 UWTUUIWWVPWHAA-XVFCMESISA-N 50205406 ((2R,3S,4R,5R)-4-amino-3-hydroxy-5-(4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate::2'-amino-2'-deoxy-2-thiouridine 5'-triphosphate::CHEMBL373780 P2Y purinoceptor 4 Homo sapiens 2400 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50205406 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50205406&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 16116566 104083754 CHEMBL373780 1733 C03517 ZINC35276442 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871785 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)n1ccc(=O)[nH]c1=S InChI=1S/C9H15N2O14P3S/c12-5-1-2-11(9(29)10-5)8-7(14)6(13)4(23-8)3-22-27(18,19)25-28(20,21)24-26(15,16)17/h1-2,4,6-8,13-14H,3H2,(H,18,19)(H,20,21)(H,10,12,29)(H2,15,16,17)/t4-,6-,7-,8-/m1/s1 KHYOUGAATNYCAZ-XVFCMESISA-N 50199176 2-thio-1-beta-D-ribofuranosyl(3H)pyrimidine-2,4-dione 5'-triphosphate::CHEMBL217803 P2Y purinoceptor 4 Homo sapiens 350 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199176&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 10174453 104079840 CHEMBL217803 C03517 ZINC13540486 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871786 N[C@@H]1[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1n1ccc(=O)[nH]c1=O InChI=1S/C9H16N3O14P3/c10-6-7(14)4(24-8(6)12-2-1-5(13)11-9(12)15)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,14H,3,10H2,(H,19,20)(H,21,22)(H,11,13,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1 RJZLOYMABJJGTA-XVFCMESISA-N 50205405 ({[({[(2R,3S,4R,5R)-4-amino-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid::CHEMBL385098 P2Y purinoceptor 4 Homo sapiens 1200 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50205405 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50205405&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 11525909 104083753 CHEMBL385098 C03517 ZINC38151343 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871799 OC1O[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H]1O InChI=1S/C14H24N2O22P4/c17-7-1-2-16(14(23)15-7)12-10(20)8(18)5(34-12)3-32-39(24,25)36-41(28,29)38-42(30,31)37-40(26,27)33-4-6-9(19)11(21)13(22)35-6/h1-2,5-6,8-13,18-22H,3-4H2,(H,24,25)(H,26,27)(H,28,29)(H,30,31)(H,15,17,23)/t5-,6+,8-,9+,10-,11+,12-,13?/m1/s1 HPDQGYIGIVCECG-IGZWYBIHSA-N 50270543 CHEMBL448985::[({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]({[hydroxy({[hydroxy({[(2S,3R,4S)-3,4,5-trihydroxyoxolan-2-yl]methoxy})phosphoryl]oxy})phosphoryl]oxy})phosphinic acid P2Y purinoceptor 4 Homo sapiens 4780 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270543&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44585516 104115714 CHEMBL448985 ZINC49833227 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871800 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC2CCCCC2)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C15H26N2O18P4/c18-11-6-7-17(15(21)16-11)14-13(20)12(19)10(31-14)8-30-36(22,23)33-38(26,27)35-39(28,29)34-37(24,25)32-9-4-2-1-3-5-9/h6-7,9-10,12-14,19-20H,1-5,8H2,(H,22,23)(H,24,25)(H,26,27)(H,28,29)(H,16,18,21)/t10-,12-,13-,14-/m1/s1 QQTHTJVJKRGTAC-FMKGYKFTSA-N 50270542 CHEMBL474887::Uridine-5'-cyclohexane-tetraphosphate P2Y purinoceptor 4 Homo sapiens >10000 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50270542 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50270542&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44585515 104115713 CHEMBL474887 ZINC49853692 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871801 OCC(O)COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C12H22N2O20P4/c15-3-6(16)4-29-35(21,22)32-37(25,26)34-38(27,28)33-36(23,24)30-5-7-9(18)10(19)11(31-7)14-2-1-8(17)13-12(14)20/h1-2,6-7,9-11,15-16,18-19H,3-5H2,(H,21,22)(H,23,24)(H,25,26)(H,27,28)(H,13,17,20)/t6?,7-,9-,10-,11-/m1/s1 OSWBYGPIMIOTRO-JANFQQFMSA-N 50271292 CHEMBL482895::Uridine-5'-alpha-glycerol-tetraphosphate P2Y purinoceptor 4 Homo sapiens 1120 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50271292 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50271292&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44586045 104116170 CHEMBL482895 ZINC49872188 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871802 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OCCC#N)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C12H19N3O18P4/c13-3-1-5-28-34(20,21)31-36(24,25)33-37(26,27)32-35(22,23)29-6-7-9(17)10(18)11(30-7)15-4-2-8(16)14-12(15)19/h2,4,7,9-11,17-18H,1,5-6H2,(H,20,21)(H,22,23)(H,24,25)(H,26,27)(H,14,16,19)/t7-,9-,10-,11-/m1/s1 YXQHIYLIDUDMIY-QCNRFFRDSA-N 50271291 CHEMBL484105::Uridine-5'-(2-cyanoethyl)-tetraphosphate P2Y purinoceptor 4 Homo sapiens 1960 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50271291 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50271291&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44586044 104116169 CHEMBL484105 ZINC49872213 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871803 CP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C10H18N2O17P4/c1-30(17,18)27-32(21,22)29-33(23,24)28-31(19,20)25-4-5-7(14)8(15)9(26-5)12-3-2-6(13)11-10(12)16/h2-3,5,7-9,14-15H,4H2,1H3,(H,17,18)(H,19,20)(H,21,22)(H,23,24)(H,11,13,16)/t5-,7-,8-,9-/m1/s1 WUXWLMUYIMIUQQ-ZOQUXTDFSA-N 50271290 CHEMBL483913::Uridine-5'-methyl(C-P)-tetraphosphate P2Y purinoceptor 4 Homo sapiens 2530 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50271290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50271290&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44586043 104116168 CHEMBL483913 ZINC49872234 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871804 COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C10H18N2O18P4/c1-25-31(17,18)28-33(21,22)30-34(23,24)29-32(19,20)26-4-5-7(14)8(15)9(27-5)12-3-2-6(13)11-10(12)16/h2-3,5,7-9,14-15H,4H2,1H3,(H,17,18)(H,19,20)(H,21,22)(H,23,24)(H,11,13,16)/t5-,7-,8-,9-/m1/s1 LRBUKMYVKOITTQ-ZOQUXTDFSA-N 50271289 CHEMBL519991::Uridine-5'-methyl-tetraphosphate P2Y purinoceptor 4 Homo sapiens 2700 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50271289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50271289&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44586042 104116167 CHEMBL519991 ZINC42887869 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871805 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(O)=O)n1ccc(=O)[nH]c1=S InChI=1S/C9H17N2O20P5S/c12-5-1-2-11(9(37)10-5)8-7(14)6(13)4(27-8)3-26-33(18,19)29-35(22,23)31-36(24,25)30-34(20,21)28-32(15,16)17/h1-2,4,6-8,13-14H,3H2,(H,18,19)(H,20,21)(H,22,23)(H,24,25)(H,10,12,37)(H2,15,16,17)/t4-,6-,7-,8-/m1/s1 HBRMVVAUYWZZGM-XVFCMESISA-N 50271254 2-Thio-uridine-5'-pentaphosphate::CHEMBL482683 P2Y purinoceptor 4 Homo sapiens 5270 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50271254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50271254&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44586027 104116143 CHEMBL482683 C03517 ZINC49867779 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871806 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(O)=O)n1ccc(=S)[nH]c1=O InChI=1S/C9H16N2O17P4S/c12-6-4(25-8(7(6)13)11-2-1-5(33)10-9(11)14)3-24-30(18,19)27-32(22,23)28-31(20,21)26-29(15,16)17/h1-2,4,6-8,12-13H,3H2,(H,18,19)(H,20,21)(H,22,23)(H,10,14,33)(H2,15,16,17)/t4-,6-,7-,8-/m1/s1 XRTFVZJYXZGIOL-XVFCMESISA-N 50271253 4-Thio-uridine-5'-tetraphosphate::CHEMBL521451 P2Y purinoceptor 4 Homo sapiens 280 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50271253 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50271253&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44586026 104116142 CHEMBL521451 C03517 ZINC42887953 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871807 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(O)=O)n1ccc(=O)[nH]c1=S InChI=1S/C9H16N2O17P4S/c12-5-1-2-11(9(33)10-5)8-7(14)6(13)4(25-8)3-24-30(18,19)27-32(22,23)28-31(20,21)26-29(15,16)17/h1-2,4,6-8,13-14H,3H2,(H,18,19)(H,20,21)(H,22,23)(H,10,12,33)(H2,15,16,17)/t4-,6-,7-,8-/m1/s1 ULAQHHDKUXIVNV-XVFCMESISA-N 50271252 2-Thio-uridine-5'-tetraphosphate::CHEMBL482485 P2Y purinoceptor 4 Homo sapiens 5520 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50271252 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50271252&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44586025 104116141 CHEMBL482485 C03517 ZINC49867467 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871808 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C9H16N2O18P4/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(26-8)3-25-31(19,20)28-33(23,24)29-32(21,22)27-30(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,23,24)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1 SBVYRQFJZOKNGO-XVFCMESISA-N 50271251 CHEMBL483502::{[({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}phosphonic acid P2Y purinoceptor 4 Homo sapiens 4640 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50271251 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50271251&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 189010 104116140 CHEMBL483502 C03517 ZINC49872132 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871809 C[C@@]1(O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1n1ccc(=O)[nH]c1=O InChI=1S/C10H17N2O15P3/c1-10(16)7(14)5(25-8(10)12-3-2-6(13)11-9(12)15)4-24-29(20,21)27-30(22,23)26-28(17,18)19/h2-3,5,7-8,14,16H,4H2,1H3,(H,20,21)(H,22,23)(H,11,13,15)(H2,17,18,19)/t5-,7-,8-,10-/m1/s1 JPNBLHSBLCCTEO-VPCXQMTMSA-N 50271224 2'-C-Methyl-uridine-5'-triphosphate::CHEMBL521487 P2Y purinoceptor 4 Homo sapiens 1260 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50271224 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50271224&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44586007 104116126 CHEMBL521487 C03517 ZINC40938445 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871810 O[C@H]1[C@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)n1ccc(=O)[nH]c1=S InChI=1S/C9H15N2O14P3S/c12-5-1-2-11(9(29)10-5)8-7(14)6(13)4(23-8)3-22-27(18,19)25-28(20,21)24-26(15,16)17/h1-2,4,6-8,13-14H,3H2,(H,18,19)(H,20,21)(H,10,12,29)(H2,15,16,17)/t4-,6-,7+,8-/m1/s1 KHYOUGAATNYCAZ-CCXZUQQUSA-N 50271223 ({[({[(2R,3S,4S,5R)-3,4-dihydroxy-5-(4-oxo-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid::CHEMBL484494 P2Y purinoceptor 4 Homo sapiens 7930 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50271223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50271223&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44586006 104116125 CHEMBL484494 C03517 ZINC40938442 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871811 NC(=O)N[C@@H]1[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1n1ccc(=O)[nH]c1=O InChI=1S/C10H17N4O15P3/c11-9(17)13-6-7(16)4(27-8(6)14-2-1-5(15)12-10(14)18)3-26-31(22,23)29-32(24,25)28-30(19,20)21/h1-2,4,6-8,16H,3H2,(H,22,23)(H,24,25)(H3,11,13,17)(H,12,15,18)(H2,19,20,21)/t4-,6-,7-,8-/m1/s1 FJFHGGAQNNVYRH-XVFCMESISA-N 50271222 ({[({[(2R,3S,4R,5R)-4-(carbamoylamino)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid::CHEMBL484295 P2Y purinoceptor 4 Homo sapiens 4640 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50271222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50271222&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44586005 104116124 CHEMBL484295 C03517 ZINC49872137 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871812 CSc1ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=S)n1 InChI=1S/C10H17N2O13P3S2/c1-30-6-2-3-12(10(29)11-6)9-8(14)7(13)5(23-9)4-22-27(18,19)25-28(20,21)24-26(15,16)17/h2-3,5,7-9,13-14H,4H2,1H3,(H,18,19)(H,20,21)(H2,15,16,17)/t5-,7-,8-,9-/m1/s1 CQECTHWDXPJZNI-ZOQUXTDFSA-N 50271188 2-Thio-4-methylthio-uridine-5'-triphosphate::CHEMBL482472 P2Y purinoceptor 4 Homo sapiens 5350 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50271188 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50271188&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44585988 104116113 CHEMBL482472 C03517 ZINC49867465 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871813 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)C(Cl)(Cl)P(O)(O)=O)n1ccc(=O)[nH]c1=S InChI=1S/C10H15Cl2N2O13P3S/c11-10(12,28(18,19)20)29(21,22)27-30(23,24)25-3-4-6(16)7(17)8(26-4)14-2-1-5(15)13-9(14)31/h1-2,4,6-8,16-17H,3H2,(H,21,22)(H,23,24)(H,13,15,31)(H2,18,19,20)/t4-,6-,7-,8-/m1/s1 BAIJAODZQNTGJN-XVFCMESISA-N 50271187 CHEMBL519835::[dichloro({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(4-oxo-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl})methyl]phosphonic acid P2Y purinoceptor 4 Homo sapiens 90 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50271187 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50271187&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44585987 104116112 CHEMBL519835 ZINC42878349 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50871814 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)C(F)(F)P(O)(O)=O)n1ccc(=O)[nH]c1=S InChI=1S/C10H15F2N2O13P3S/c11-10(12,28(18,19)20)29(21,22)27-30(23,24)25-3-4-6(16)7(17)8(26-4)14-2-1-5(15)13-9(14)31/h1-2,4,6-8,16-17H,3H2,(H,21,22)(H,23,24)(H,13,15,31)(H2,18,19,20)/t4-,6-,7-,8-/m1/s1 SMBXLASXMSOQPT-XVFCMESISA-N 50271186 ({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(4-oxo-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}difluoromethyl)phosphonic acid::CHEMBL484290 P2Y purinoceptor 4 Homo sapiens 8110 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50271186 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50271186&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44585986 104116111 CHEMBL484290 ZINC49872125 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50907361 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)n1cc(F)c(=O)[nH]c1=O InChI=1S/C9H14FN2O15P3/c10-3-1-12(9(16)11-7(3)15)8-6(14)5(13)4(25-8)2-24-29(20,21)27-30(22,23)26-28(17,18)19/h1,4-6,8,13-14H,2H2,(H,20,21)(H,22,23)(H,11,15,16)(H2,17,18,19)/t4-,5-,6-,8-/m1/s1 AREUQFTVCMGENT-UAKXSSHOSA-N 50306705 ((2R,3S,4R,5R)-5-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate::CHEMBL1774 P2Y purinoceptor 4 Homo sapiens 600 ChEMBL 10.1021/jm901450d 10.7270/Q2ZW1MWR 20095577 Ginsburg-Shmuel, T; Haas, M; Schumann, M; Reiser, G; Kalid, O; Stern, N; Fischer, B Bar-Ilan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306705 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306705&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 10255482 104161066 CHEMBL1774 C03517 ZINC31392792 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50907364 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(O)=O)n1cc(F)c(=O)[nH]c1=O InChI=1S/C9H13FN2O12P2/c10-3-1-12(9(16)11-7(3)15)8-6(14)5(13)4(23-8)2-22-26(20,21)24-25(17,18)19/h1,4-6,8,13-14H,2H2,(H,20,21)(H,11,15,16)(H2,17,18,19)/t4-,5-,6-,8-/m1/s1 FOZCNVFQOJRHFF-UAKXSSHOSA-N 50306707 ((2R,3S,4R,5R)-5-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl trihydrogen diphosphate::CHEMBL590981 P2Y purinoceptor 4 Homo sapiens 3500 ChEMBL 10.1021/jm901450d 10.7270/Q2ZW1MWR 20095577 Ginsburg-Shmuel, T; Haas, M; Schumann, M; Reiser, G; Kalid, O; Stern, N; Fischer, B Bar-Ilan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306707 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306707&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 10432343 104161068 CHEMBL590981 C03517 ZINC13542911 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50907370 O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)n1cc(Br)c(=O)[nH]c1=O InChI=1S/C9H14BrN2O15P3/c10-3-1-12(9(16)11-7(3)15)8-6(14)5(13)4(25-8)2-24-29(20,21)27-30(22,23)26-28(17,18)19/h1,4-6,8,13-14H,2H2,(H,20,21)(H,22,23)(H,11,15,16)(H2,17,18,19)/t4-,5-,6-,8-/m1/s1 IWFHOSULCAJGRM-UAKXSSHOSA-N 50199192 ((2R,3S,4R,5R)-5-(5-bromo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate::5-bromo-1-beta-D-ribofuranosyl(3H)pyrimidine-2,4-dione 5'-triphosphate::5-bromo-UTP::CHEMBL384527 P2Y purinoceptor 4 Homo sapiens 10000 ChEMBL 10.1021/jm901450d 10.7270/Q2ZW1MWR 20095577 Ginsburg-Shmuel, T; Haas, M; Schumann, M; Reiser, G; Kalid, O; Stern, N; Fischer, B Bar-Ilan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199192 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199192&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search BUP 9872620 104079856 CHEMBL384527 C03517 ZINC38149754 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50907898 Nc1c(cc(Nc2ccc(Nc3nc(Cl)nc(Nc4cccc(c4)S([O-])(=O)=O)n3)c(c2)S([O-])(=O)=O)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C29H20ClN7O11S3/c30-27-35-28(33-13-4-3-5-15(10-13)49(40,41)42)37-29(36-27)34-18-9-8-14(11-20(18)50(43,44)45)32-19-12-21(51(46,47)48)24(31)23-22(19)25(38)16-6-1-2-7-17(16)26(23)39/h1-12,32H,31H2,(H,40,41,42)(H,43,44,45)(H,46,47,48)(H2,33,34,35,36,37)/p-3 JQYMGXZJTCOARG-UHFFFAOYSA-K 50029031 1-Amino-4-{4-[4-chloro-6-(3-sulfo-phenylamino)-[1,3,5]triazin-2-ylamino]-3-sulfo-phenylamino}-9,10-dioxo-9,10-dihydro-anthracene-2-sulfonic acid1-Amino-4-{4-[4-chloro-6-(4-sulfo-phenylamino)-[1,3,5]triazin-2-ylamino]-3-sulfo-phenylamino}-9,10-dioxo-9,10-dihydro-anthracene-2-sulfonic acid::CHEMBL223344::CID44285648::basilen blue::cibacron blue (mixer, meta and para isomers P2Y purinoceptor 4 Homo sapiens 9790 ChEMBL 10.1021/jm901851t 10.7270/Q2DZ097V 20146483 Baqi, Y; Lee, SY; Iqbal, J; Ripphausen, P; Lehr, A; Scheiff, AB; Zimmermann, H; Bajorath, J; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029031&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44285647 103938145 CHEMBL223344 C13746 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50907899 Nc1c2C(=O)c3ccccc3C(=O)c2c(Nc2ccccc2)cc1S([O-])(=O)=O InChI=1S/C20H14N2O5S/c21-18-15(28(25,26)27)10-14(22-11-6-2-1-3-7-11)16-17(18)20(24)13-9-5-4-8-12(13)19(16)23/h1-10,22H,21H2,(H,25,26,27)/p-1 OPBOOIFXQHPAPJ-UHFFFAOYSA-M 50227032 CHEMBL256057::acid blue 25::sodium 1-amino-9,10-dioxo-4-(phenylamino)-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 25800 ChEMBL 10.1021/jm901851t 10.7270/Q2DZ097V 20146483 Baqi, Y; Lee, SY; Iqbal, J; Ripphausen, P; Lehr, A; Scheiff, AB; Zimmermann, H; Bajorath, J; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227032&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 7072970 104097288 CHEMBL256057 ZINC04016164 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50907900 Nc1c(cc(Nc2ccc(O)cc2)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C20H14N2O6S/c21-18-15(29(26,27)28)9-14(22-10-5-7-11(23)8-6-10)16-17(18)20(25)13-4-2-1-3-12(13)19(16)24/h1-9,22-23H,21H2,(H,26,27,28)/p-1 KFBGXLCLNATBFL-UHFFFAOYSA-M 50268725 CHEMBL496030::sodium 1-amino-4-(4-hydroxyphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 2370 ChEMBL 10.1021/jm901851t 10.7270/Q2DZ097V 20146483 Baqi, Y; Lee, SY; Iqbal, J; Ripphausen, P; Lehr, A; Scheiff, AB; Zimmermann, H; Bajorath, J; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50268725 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50268725&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 59448191 104114982 CHEMBL496030 ZINC05162649 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50907901 Nc1c(cc(Nc2ccc(F)cc2C(O)=O)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C21H13FN2O7S/c22-9-5-6-13(12(7-9)21(27)28)24-14-8-15(32(29,30)31)18(23)17-16(14)19(25)10-3-1-2-4-11(10)20(17)26/h1-8,24H,23H2,(H,27,28)(H,29,30,31)/p-1 OBFSYBSKXOCXQH-UHFFFAOYSA-M 50307835 CHEMBL590956::Sodium 1-amino-4-[4-fluoro-2-carboxyphenylamino]-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens >10000 ChEMBL 10.1021/jm901851t 10.7270/Q2DZ097V 20146483 Baqi, Y; Lee, SY; Iqbal, J; Ripphausen, P; Lehr, A; Scheiff, AB; Zimmermann, H; Bajorath, J; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50307835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50307835&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91934095 104162196 CHEMBL590956 ZINC45335732 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50907902 Nc1c2C(=O)c3ccccc3C(=O)c2c(Nc2ccc3cc4ccccc4cc3c2)cc1S([O-])(=O)=O InChI=1S/C28H18N2O5S/c29-26-23(36(33,34)35)14-22(24-25(26)28(32)21-8-4-3-7-20(21)27(24)31)30-19-10-9-17-11-15-5-1-2-6-16(15)12-18(17)13-19/h1-14,30H,29H2,(H,33,34,35)/p-1 JXFRJOYKTCEJDG-UHFFFAOYSA-M 50307836 CHEMBL608559::Sodium 1-Amino-4-(2-anthracenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens >10000 ChEMBL 10.1021/jm901851t 10.7270/Q2DZ097V 20146483 Baqi, Y; Lee, SY; Iqbal, J; Ripphausen, P; Lehr, A; Scheiff, AB; Zimmermann, H; Bajorath, J; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50307836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50307836&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91934096 104162197 CHEMBL608559 ZINC45391793 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50907903 Nc1c2C(=O)c3ccccc3C(=O)c2c(Nc2cccc3ccccc23)cc1S([O-])(=O)=O InChI=1S/C24H16N2O5S/c25-22-19(32(29,30)31)12-18(26-17-11-5-7-13-6-1-2-8-14(13)17)20-21(22)24(28)16-10-4-3-9-15(16)23(20)27/h1-12,26H,25H2,(H,29,30,31)/p-1 ZHQRPIRGSWEALJ-UHFFFAOYSA-M 50268574 CHEMBL498423::Sodium 1-Amino-4-(1-naphthylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate::Sodium 1-amino-4-[1-naphthylamino]-9,10-dioxo-9,10 dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 10100 ChEMBL 10.1021/jm901851t 10.7270/Q2DZ097V 20146483 Baqi, Y; Lee, SY; Iqbal, J; Ripphausen, P; Lehr, A; Scheiff, AB; Zimmermann, H; Bajorath, J; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50268574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50268574&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 24868314 104114923 CHEMBL498423 ZINC13831235 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50921061 Nc1c2C(=O)c3ccccc3C(=O)c2c(Nc2ccccc2)cc1S([O-])(=O)=O InChI=1S/C20H14N2O5S/c21-18-15(28(25,26)27)10-14(22-11-6-2-1-3-7-11)16-17(18)20(24)13-9-5-4-8-12(13)19(16)23/h1-10,22H,21H2,(H,25,26,27)/p-1 OPBOOIFXQHPAPJ-UHFFFAOYSA-M 50227032 CHEMBL256057::acid blue 25::sodium 1-amino-9,10-dioxo-4-(phenylamino)-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 25800 ChEMBL 10.1021/jm1012193 10.7270/Q2VH5PTG 21207957 Baqi, Y; Hausmann, R; Rosefort, C; Rettinger, J; Schmalzing, G; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227032&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 7072970 104097288 CHEMBL256057 ZINC04016164 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50921062 Cc1cccc(Nc2cc(c(N)c3C(=O)c4ccccc4C(=O)c23)S([O-])(=O)=O)c1 InChI=1S/C21H16N2O5S/c1-11-5-4-6-12(9-11)23-15-10-16(29(26,27)28)19(22)18-17(15)20(24)13-7-2-3-8-14(13)21(18)25/h2-10,23H,22H2,1H3,(H,26,27,28)/p-1 AYMOWRNYHLSUHI-UHFFFAOYSA-M 50336787 CHEMBL445413::sodium 1-amino-9,10-dioxo-4-(m-tolylamino)-9,10-dihydroanthracene-2-sulfonate::sodium 4-(m-toluidino)-1-amino-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens >10000 ChEMBL 10.1021/jm1012193 10.7270/Q2VH5PTG 21207957 Baqi, Y; Hausmann, R; Rosefort, C; Rettinger, J; Schmalzing, G; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336787&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91932498 125086889 CHEMBL445413 ZINC29131032 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50921063 Nc1c(cc(Nc2ccc(O)cc2)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C20H14N2O6S/c21-18-15(29(26,27)28)9-14(22-10-5-7-11(23)8-6-10)16-17(18)20(25)13-4-2-1-3-12(13)19(16)24/h1-9,22-23H,21H2,(H,26,27,28)/p-1 KFBGXLCLNATBFL-UHFFFAOYSA-M 50268725 CHEMBL496030::sodium 1-amino-4-(4-hydroxyphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 2220 ChEMBL 10.1021/jm1012193 10.7270/Q2VH5PTG 21207957 Baqi, Y; Hausmann, R; Rosefort, C; Rettinger, J; Schmalzing, G; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50268725 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50268725&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 59448191 104114982 CHEMBL496030 ZINC05162649 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50921064 COc1cccc(Nc2cc(c(N)c3C(=O)c4ccccc4C(=O)c23)S([O-])(=O)=O)c1 InChI=1S/C21H16N2O6S/c1-29-12-6-4-5-11(9-12)23-15-10-16(30(26,27)28)19(22)18-17(15)20(24)13-7-2-3-8-14(13)21(18)25/h2-10,23H,22H2,1H3,(H,26,27,28)/p-1 UOXSNOOWASRNHS-UHFFFAOYSA-M 50336768 CHEMBL1671995::sodium 1-amino-4-(3-methoxyphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 10000 ChEMBL 10.1021/jm1012193 10.7270/Q2VH5PTG 21207957 Baqi, Y; Hausmann, R; Rosefort, C; Rettinger, J; Schmalzing, G; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336768 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336768&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 59448192 125086870 CHEMBL1671995 ZINC33606789 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50921065 Nc1c(cc(Nc2cccc(Cl)c2)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C20H13ClN2O5S/c21-10-4-3-5-11(8-10)23-14-9-15(29(26,27)28)18(22)17-16(14)19(24)12-6-1-2-7-13(12)20(17)25/h1-9,23H,22H2,(H,26,27,28)/p-1 NTYGNNJMCYGTJX-UHFFFAOYSA-M 50227020 CHEMBL271672::sodium 1-amino-4-(3-chlorophenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 21800 ChEMBL 10.1021/jm1012193 10.7270/Q2VH5PTG 21207957 Baqi, Y; Hausmann, R; Rosefort, C; Rettinger, J; Schmalzing, G; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227020&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 59448189 104097286 CHEMBL271672 ZINC29130781 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50921066 Nc1c(cc(Nc2cccc(Cc3ccccc3)c2)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C27H20N2O5S/c28-25-22(35(32,33)34)15-21(23-24(25)27(31)20-12-5-4-11-19(20)26(23)30)29-18-10-6-9-17(14-18)13-16-7-2-1-3-8-16/h1-12,14-15,29H,13,28H2,(H,32,33,34)/p-1 PWFGNCPUVKMCGC-UHFFFAOYSA-M 50336801 CHEMBL1672100::Sodium1-Amino-4-(3-benzylphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens >10000 ChEMBL 10.1021/jm1012193 10.7270/Q2VH5PTG 21207957 Baqi, Y; Hausmann, R; Rosefort, C; Rettinger, J; Schmalzing, G; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336801 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336801&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91932509 125086903 CHEMBL1672100 ZINC66079286 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50921067 Nc1c(cc(Nc2ccc(c(Nc3nc(Cl)nc(Cl)n3)c2)S([O-])(=O)=O)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C23H14Cl2N6O8S2/c24-21-29-22(25)31-23(30-21)28-12-7-9(5-6-14(12)40(34,35)36)27-13-8-15(41(37,38)39)18(26)17-16(13)19(32)10-3-1-2-4-11(10)20(17)33/h1-8,27H,26H2,(H,34,35,36)(H,37,38,39)(H,28,29,30,31)/p-2 RTLULCVBFCRQKI-UHFFFAOYSA-L 50336781 CHEMBL1672104::Disodium 1-Amino-4-[3-(4,6-dichloro[1,3,5]triazine-2-ylamino)-4-sulfophenylamino]-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens >10000 ChEMBL 10.1021/jm1012193 10.7270/Q2VH5PTG 21207957 Baqi, Y; Hausmann, R; Rosefort, C; Rettinger, J; Schmalzing, G; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336781 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336781&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 45100265 125086883 CHEMBL1672104 ZINC06830021 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50921068 Nc1c(cc(Nc2cc(Nc3nc(Cl)nc(Cl)n3)cc(c2)C(O)=O)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C24H14Cl2N6O7S/c25-22-30-23(26)32-24(31-22)29-11-6-9(21(35)36)5-10(7-11)28-14-8-15(40(37,38)39)18(27)17-16(14)19(33)12-3-1-2-4-13(12)20(17)34/h1-8,28H,27H2,(H,35,36)(H,37,38,39)(H,29,30,31,32)/p-1 WNDJATPAYNDPLE-UHFFFAOYSA-M 50268874 CHEMBL499580::Sodium 1-Amino-4-[3-(4,6-dichloro-[1,3,5]triazine-2-ylamino)-5-carboxyphenylamino]-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 1450 ChEMBL 10.1021/jm1012193 10.7270/Q2VH5PTG 21207957 Baqi, Y; Hausmann, R; Rosefort, C; Rettinger, J; Schmalzing, G; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50268874 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50268874&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91935135 104115032 CHEMBL499580 ZINC49888955 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50921069 Nc1c(cc(Nc2ccc(Nc3nc(Cl)nc(Cl)n3)cc2)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C23H14Cl2N6O5S/c24-21-29-22(25)31-23(30-21)28-11-7-5-10(6-8-11)27-14-9-15(37(34,35)36)18(26)17-16(14)19(32)12-3-1-2-4-13(12)20(17)33/h1-9,27H,26H2,(H,34,35,36)(H,28,29,30,31)/p-1 UIPXJMQJSGBYIZ-UHFFFAOYSA-M 50268875 CHEMBL496401::Sodium 1-amino-4-[4-(4,6-dichloro-[1,3,5]triazine-2-ylamino)-phenylamino]-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 10000 ChEMBL 10.1021/jm1012193 10.7270/Q2VH5PTG 21207957 Baqi, Y; Hausmann, R; Rosefort, C; Rettinger, J; Schmalzing, G; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50268875 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50268875&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91935136 104115033 CHEMBL496401 ZINC49888706 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50921070 Nc1c(cc(Nc2cccc(Nc3nc(Cl)nc(Cl)n3)c2)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C23H14Cl2N6O5S/c24-21-29-22(25)31-23(30-21)28-11-5-3-4-10(8-11)27-14-9-15(37(34,35)36)18(26)17-16(14)19(32)12-6-1-2-7-13(12)20(17)33/h1-9,27H,26H2,(H,34,35,36)(H,28,29,30,31)/p-1 BLCUJFVIEUPNOP-UHFFFAOYSA-M 50336796 CHEMBL1672105::Sodium 1-Amino-4-[3-(4,6-dichloro[1,3,5]triazine-2-ylamino)-phenylamino]-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 10000 ChEMBL 10.1021/jm1012193 10.7270/Q2VH5PTG 21207957 Baqi, Y; Hausmann, R; Rosefort, C; Rettinger, J; Schmalzing, G; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336796&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91932506 125086898 CHEMBL1672105 ZINC66076201 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50921071 COc1nc(Cl)nc(Nc2ccc(Nc3cc(c(N)c4C(=O)c5ccccc5C(=O)c34)S([O-])(=O)=O)cc2S([O-])(=O)=O)n1 InChI=1S/C24H17ClN6O9S2/c1-40-24-30-22(25)29-23(31-24)28-13-7-6-10(8-15(13)41(34,35)36)27-14-9-16(42(37,38)39)19(26)18-17(14)20(32)11-4-2-3-5-12(11)21(18)33/h2-9,27H,26H2,1H3,(H,34,35,36)(H,37,38,39)(H,28,29,30,31)/p-2 MQIWIMRDOFFCID-UHFFFAOYSA-L 50268876 CHEMBL509572::Disodium 1-amino-4-[4-(4-chloro-6-methoxy-[1,3,5]triazine-2-ylamino)-3-sulfophenylamino]-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens >10000 ChEMBL 10.1021/jm1012193 10.7270/Q2VH5PTG 21207957 Baqi, Y; Hausmann, R; Rosefort, C; Rettinger, J; Schmalzing, G; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50268876 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50268876&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91935137 104115034 CHEMBL509572 ZINC49899400 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50921072 Nc1c(cc(Nc2ccc(Nc3nc(=O)[nH]c(=O)[nH]3)cc2)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C23H16N6O7S/c24-18-15(37(34,35)36)9-14(16-17(18)20(31)13-4-2-1-3-12(13)19(16)30)25-10-5-7-11(8-6-10)26-21-27-22(32)29-23(33)28-21/h1-9,25H,24H2,(H,34,35,36)(H3,26,27,28,29,32,33)/p-1 SUBUVWLVTJOKQD-UHFFFAOYSA-M 50336782 CHEMBL1672106::Sodium 1-Amino-4-[4-(4,6-dihydroxy[1,3,5]triazine-2-ylamino)-phenylamino]-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 10000 ChEMBL 10.1021/jm1012193 10.7270/Q2VH5PTG 21207957 Baqi, Y; Hausmann, R; Rosefort, C; Rettinger, J; Schmalzing, G; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336782&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91932496 125086884 CHEMBL1672106 ZINC66076903 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50921196 Nc1c(cc(Nc2ccc(Nc3nc(Cl)nc(Nc4cccc(c4)S([O-])(=O)=O)n3)c(c2)S([O-])(=O)=O)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C29H20ClN7O11S3/c30-27-35-28(33-13-4-3-5-15(10-13)49(40,41)42)37-29(36-27)34-18-9-8-14(11-20(18)50(43,44)45)32-19-12-21(51(46,47)48)24(31)23-22(19)25(38)16-6-1-2-7-17(16)26(23)39/h1-12,32H,31H2,(H,40,41,42)(H,43,44,45)(H,46,47,48)(H2,33,34,35,36,37)/p-3 JQYMGXZJTCOARG-UHFFFAOYSA-K 50029031 1-Amino-4-{4-[4-chloro-6-(3-sulfo-phenylamino)-[1,3,5]triazin-2-ylamino]-3-sulfo-phenylamino}-9,10-dioxo-9,10-dihydro-anthracene-2-sulfonic acid1-Amino-4-{4-[4-chloro-6-(4-sulfo-phenylamino)-[1,3,5]triazin-2-ylamino]-3-sulfo-phenylamino}-9,10-dioxo-9,10-dihydro-anthracene-2-sulfonic acid::CHEMBL223344::CID44285648::basilen blue::cibacron blue (mixer, meta and para isomers P2Y purinoceptor 4 Homo sapiens 9790 ChEMBL 10.1021/jm1012193 10.7270/Q2VH5PTG 21207957 Baqi, Y; Hausmann, R; Rosefort, C; Rettinger, J; Schmalzing, G; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029031&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44285647 103938145 CHEMBL223344 C13746 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50985218 O[C@H]1[C@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)O[C@@H]([C@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C18H26N4O23P4/c23-9-1-3-21(17(29)19-9)15-13(27)11(25)7(41-15)5-39-46(31,32)43-48(35,36)45-49(37,38)44-47(33,34)40-6-8-12(26)14(28)16(42-8)22-4-2-10(24)20-18(22)30/h1-4,7-8,11-16,25-28H,5-6H2,(H,31,32)(H,33,34)(H,35,36)(H,37,38)(H,19,23,29)(H,20,24,30)/t7-,8+,11-,12+,13-,14+,15-,16+ NMLMACJWHPHKGR-WWMDGMSNSA-N 50403873 CHEMBL1207447 P2Y purinoceptor 4 Homo sapiens 400 ChEMBL 10.1016/s0960-894x(00)00612-0 10.7270/Q2BG2PH9 11206448 Pendergast, W; Yerxa, BR; Douglass, JG; Shaver, SR; Dougherty, RW; Redick, CC; Sims, IF; Rideout, JL Inspire Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403873 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403873&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44457427 163352897 CHEMBL1207447 ZINC95543482 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50985222 O[C@H]1[C@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)O[C@@H]([C@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C18H28N4O29P6/c23-9-1-3-21(17(29)19-9)15-13(27)11(25)7(45-15)5-43-52(31,32)47-54(35,36)49-56(39,40)51-57(41,42)50-55(37,38)48-53(33,34)44-6-8-12(26)14(28)16(46-8)22-4-2-10(24)20-18(22)30/h1-4,7-8,11-16,25-28H,5-6H2,(H,31,32)(H,33,34)(H,35,36)(H,37,38)(H,39,40)(H,41,42)(H,19,23,29)(H,20,24,30)/t7-,8+,11-,12+,13-,14+,15-,16+ MHMPIASZRJDSQE-WWMDGMSNSA-N 50403874 CHEMBL2113465 P2Y purinoceptor 4 Homo sapiens >30000 ChEMBL 10.1016/s0960-894x(00)00612-0 10.7270/Q2BG2PH9 11206448 Pendergast, W; Yerxa, BR; Douglass, JG; Shaver, SR; Dougherty, RW; Redick, CC; Sims, IF; Rideout, JL Inspire Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403874 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403874&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 71459959 163352898 CHEMBL2113465 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50985225 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C9H15N2O15P3/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1 PGAVKCOVUIYSFO-XVFCMESISA-N 50118213 5'-UTP::CHEMBL336296::H4utp::UTP::uridine 5'-(tetrahydrogen triphosphate)::uridine 5'-triphosphoric acid P2Y purinoceptor 4 Homo sapiens 100 ChEMBL 10.1016/s0960-894x(00)00612-0 10.7270/Q2BG2PH9 11206448 Pendergast, W; Yerxa, BR; Douglass, JG; Shaver, SR; Dougherty, RW; Redick, CC; Sims, IF; Rideout, JL Inspire Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118213&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search UTP 6133 104011550 15713 CHEMBL336296 1734 C03517 ZINC19796107 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50985227 O[C@H]1[C@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)O[C@@H]([C@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C18H29N4O32P7/c23-9-1-3-21(17(29)19-9)15-13(27)11(25)7(47-15)5-45-55(31,32)49-57(35,36)51-59(39,40)53-61(43,44)54-60(41,42)52-58(37,38)50-56(33,34)46-6-8-12(26)14(28)16(48-8)22-4-2-10(24)20-18(22)30/h1-4,7-8,11-16,25-28H,5-6H2,(H,31,32)(H,33,34)(H,35,36)(H,37,38)(H,39,40)(H,41,42)(H,43,44)(H,19,23,29)(H,20,24,30)/t7-,8+,11-,12+,13-,14+,15-,16+ KUEVKDRCJQJOTF-WWMDGMSNSA-N 50403875 CHEMBL2113398 P2Y purinoceptor 4 Homo sapiens >30000 ChEMBL 10.1016/s0960-894x(00)00612-0 10.7270/Q2BG2PH9 11206448 Pendergast, W; Yerxa, BR; Douglass, JG; Shaver, SR; Dougherty, RW; Redick, CC; Sims, IF; Rideout, JL Inspire Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403875 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403875&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 71459956 163352899 CHEMBL2113398 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50985230 O[C@H]1[C@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)O[C@@H]([C@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C18H25N4O20P3/c23-9-1-3-21(17(29)19-9)15-13(27)11(25)7(39-15)5-37-43(31,32)41-45(35,36)42-44(33,34)38-6-8-12(26)14(28)16(40-8)22-4-2-10(24)20-18(22)30/h1-4,7-8,11-16,25-28H,5-6H2,(H,31,32)(H,33,34)(H,35,36)(H,19,23,29)(H,20,24,30)/t7-,8+,11-,12+,13-,14+,15-,16+ JPNWHMPVXHYIKN-WWMDGMSNSA-N 50371609 CHEMBL1162193 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1016/s0960-894x(00)00612-0 10.7270/Q2BG2PH9 11206448 Pendergast, W; Yerxa, BR; Douglass, JG; Shaver, SR; Dougherty, RW; Redick, CC; Sims, IF; Rideout, JL Inspire Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50371609 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50371609&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44457390 160850710 CHEMBL1162193 ZINC49803938 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50985223 O[C@H]1[C@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)O[C@@H]([C@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C18H27N4O26P5/c23-9-1-3-21(17(29)19-9)15-13(27)11(25)7(43-15)5-41-49(31,32)45-51(35,36)47-53(39,40)48-52(37,38)46-50(33,34)42-6-8-12(26)14(28)16(44-8)22-4-2-10(24)20-18(22)30/h1-4,7-8,11-16,25-28H,5-6H2,(H,31,32)(H,33,34)(H,35,36)(H,37,38)(H,39,40)(H,19,23,29)(H,20,24,30)/t7-,8+,11-,12+,13-,14+,15-,16+ DTPUCAAWIZAYGN-WWMDGMSNSA-N 50403872 CHEMBL2113401 P2Y purinoceptor 4 Homo sapiens >20000 ChEMBL 10.1016/s0960-894x(00)00612-0 10.7270/Q2BG2PH9 11206448 Pendergast, W; Yerxa, BR; Douglass, JG; Shaver, SR; Dougherty, RW; Redick, CC; Sims, IF; Rideout, JL Inspire Pharmaceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403872&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 71459957 163352896 CHEMBL2113401 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 51014274 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C9H15N2O15P3/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1 PGAVKCOVUIYSFO-XVFCMESISA-N 50118213 5'-UTP::CHEMBL336296::H4utp::UTP::uridine 5'-(tetrahydrogen triphosphate)::uridine 5'-triphosphoric acid P2Y purinoceptor 4 Homo sapiens 500 ChEMBL 10.1021/jm901450d 10.7270/Q2ZW1MWR 20095577 Ginsburg-Shmuel, T; Haas, M; Schumann, M; Reiser, G; Kalid, O; Stern, N; Fischer, B Bar-Ilan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118213&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search UTP 6133 104011550 15713 CHEMBL336296 1734 C03517 ZINC19796107 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 51003889 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C9H15N2O15P3/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1 PGAVKCOVUIYSFO-XVFCMESISA-N 50118213 5'-UTP::CHEMBL336296::H4utp::UTP::uridine 5'-(tetrahydrogen triphosphate)::uridine 5'-triphosphoric acid P2Y purinoceptor 4 Homo sapiens 73 ChEMBL 10.1021/jm060903o 10.7270/Q2PK0GZ1 17302398 Ivanov, AA; Ko, H; Cosyn, L; Maddileti, S; Besada, P; Fricks, I; Costanzi, S; Harden, TK; Calenbergh, SV; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118213&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search UTP 6133 104011550 15713 CHEMBL336296 1734 C03517 ZINC19796107 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50998545 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C9H15N2O15P3/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1 PGAVKCOVUIYSFO-XVFCMESISA-N 50118213 5'-UTP::CHEMBL336296::H4utp::UTP::uridine 5'-(tetrahydrogen triphosphate)::uridine 5'-triphosphoric acid P2Y purinoceptor 4 Homo sapiens 2500 ChEMBL 10.1021/jm020046y 10.7270/Q2VX0H71 12213051 Jacobson, KA; Jarvis, MF; Williams, M National Institute of Diabetes http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118213&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search UTP 6133 104011550 15713 CHEMBL336296 1734 C03517 ZINC19796107 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 51006652 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C9H15N2O15P3/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1 PGAVKCOVUIYSFO-XVFCMESISA-N 50118213 5'-UTP::CHEMBL336296::H4utp::UTP::uridine 5'-(tetrahydrogen triphosphate)::uridine 5'-triphosphoric acid P2Y purinoceptor 4 Homo sapiens 90 ChEMBL 10.1016/j.bmc.2008.05.013 10.7270/Q2K07569 18514530 Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118213&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search UTP 6133 104011550 15713 CHEMBL336296 1734 C03517 ZINC19796107 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 51003404 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C9H15N2O15P3/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1 PGAVKCOVUIYSFO-XVFCMESISA-N 50118213 5'-UTP::CHEMBL336296::H4utp::UTP::uridine 5'-(tetrahydrogen triphosphate)::uridine 5'-triphosphoric acid P2Y purinoceptor 4 Homo sapiens 87 ChEMBL 10.1021/jm060848j 10.7270/Q2SN09RW 17125260 El-Tayeb, A; Qi, A; Muller, CE University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118213&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search UTP 6133 104011550 15713 CHEMBL336296 1734 C03517 ZINC19796107 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 51010362 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C9H15N2O15P3/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1 PGAVKCOVUIYSFO-XVFCMESISA-N 50118213 5'-UTP::CHEMBL336296::H4utp::UTP::uridine 5'-(tetrahydrogen triphosphate)::uridine 5'-triphosphoric acid P2Y purinoceptor 4 Homo sapiens 480 ChEMBL 10.1016/j.ejmech.2008.07.015 10.7270/Q2W37X7P 18760862 Eliahu, SE; Camden, J; Lecka, J; Weisman, GA; Sevigny, J; Gelinas, S; Fischer, B Bar-Ilan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118213&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search UTP 6133 104011550 15713 CHEMBL336296 1734 C03517 ZINC19796107 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 51004673 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C9H15N2O15P3/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1 PGAVKCOVUIYSFO-XVFCMESISA-N 50118213 5'-UTP::CHEMBL336296::H4utp::UTP::uridine 5'-(tetrahydrogen triphosphate)::uridine 5'-triphosphoric acid P2Y purinoceptor 4 Homo sapiens 39 ChEMBL 10.1016/j.bmcl.2006.09.017 10.7270/Q2CC11JS 17011188 Brookings, D; Davenport, RJ; Davis, J; Galvin, FC; Lloyd, S; Mack, SR; Owens, R; Sabin, V; Wynn, J UCB-Group http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118213&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search UTP 6133 104011550 15713 CHEMBL336296 1734 C03517 ZINC19796107 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 51004676 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C9H15N2O15P3/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1 PGAVKCOVUIYSFO-XVFCMESISA-N 50118213 5'-UTP::CHEMBL336296::H4utp::UTP::uridine 5'-(tetrahydrogen triphosphate)::uridine 5'-triphosphoric acid P2Y purinoceptor 4 Homo sapiens 39 ChEMBL 10.1016/j.bmcl.2006.10.038 10.7270/Q2QN67MX 17079144 Davenport, RJ; Diaz, P; Galvin, FC; Lloyd, S; Mack, SR; Owens, R; Sabin, V; Wynn, J UCB-Group http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118213&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search UTP 6133 104011550 15713 CHEMBL336296 1734 C03517 ZINC19796107 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50998252 O[C@@H]1[C@H](O)[C@]2(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C[C@@H]2[C@H]1n1ccc(=O)[nH]c1=O InChI=1S/C11H17N2O14P3/c14-6-1-2-13(10(17)12-6)7-5-3-11(5,9(16)8(7)15)4-25-29(21,22)27-30(23,24)26-28(18,19)20/h1-2,5,7-9,15-16H,3-4H2,(H,21,22)(H,23,24)(H,12,14,17)(H2,18,19,20)/t5-,7-,8+,9+,11+/m1/s1 XWFVJTIKQWQNID-KAACBLBJSA-N 50306712 ((1R,2R,3S,4R,5S)-4-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,3-dihydroxybicyclo[3.1.0]hexan-1-yl)methyl tetrahydrogen triphosphate::CHEMBL606210 P2Y purinoceptor 4 Homo sapiens 85 ChEMBL 10.1021/jm010369e 10.7270/Q2JS9R58 11754592 Kim, HS; Ravi, RG; Marquez, VE; Maddileti, S; Wihlborg, AK; Erlinge, D; Malmsjo, M; Boyer, JL; Harden, TK; Jacobson, KA National Institute of Diabetes http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306712 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306712&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 10929115 104161073 CHEMBL606210 C03517 ZINC45389461 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50998258 O[C@@H]1[C@H](O)[C@]2(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C[C@@H]2[C@H]1n1ccc(=O)[nH]c1=O InChI=1S/C11H17N2O14P3/c14-6-1-2-13(10(17)12-6)7-5-3-11(5,9(16)8(7)15)4-25-29(21,22)27-30(23,24)26-28(18,19)20/h1-2,5,7-9,15-16H,3-4H2,(H,21,22)(H,23,24)(H,12,14,17)(H2,18,19,20)/t5-,7-,8+,9+,11+/m1/s1 XWFVJTIKQWQNID-KAACBLBJSA-N 50306712 ((1R,2R,3S,4R,5S)-4-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,3-dihydroxybicyclo[3.1.0]hexan-1-yl)methyl tetrahydrogen triphosphate::CHEMBL606210 P2Y purinoceptor 4 Homo sapiens 85.0 ChEMBL 10.1021/jm010369e 10.7270/Q2JS9R58 11754592 Kim, HS; Ravi, RG; Marquez, VE; Maddileti, S; Wihlborg, AK; Erlinge, D; Malmsjo, M; Boyer, JL; Harden, TK; Jacobson, KA National Institute of Diabetes http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306712 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306712&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 10929115 104161073 CHEMBL606210 C03517 ZINC45389461 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 51025060 [BH3-]P(=O)(OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O)OP([O-])(=O)OP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C18H28BN4O22P4/c19-46(32,39-5-7-11(26)13(28)15(41-7)22-3-1-9(24)20-17(22)30)43-48(35,36)45-49(37,38)44-47(33,34)40-6-8-12(27)14(29)16(42-8)23-4-2-10(25)21-18(23)31/h1-4,7-8,11-16,26-29H,5-6H2,19H3,(H,33,34)(H,35,36)(H,37,38)(H,20,24,30)(H,21,25,31)/q-1/p-3/t7-,8-,11-,12-,13-,14-,15-,16-,46?/m1/s1 QHGIIPGNSPHLFM-VMOKYWTHSA-K 50364066 CHEMBL1950678 P2Y purinoceptor 4 Homo sapiens 9400 ChEMBL 10.1021/jm2013198 10.7270/Q2Z60PJT 22107038 Yelovitch, S; Camden, J; Weisman, GA; Fischer, B Bar-Ilan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50364066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50364066&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91930575 136968128 CHEMBL1950678 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 51025062 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C9H15N2O15P3/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1 PGAVKCOVUIYSFO-XVFCMESISA-N 50118213 5'-UTP::CHEMBL336296::H4utp::UTP::uridine 5'-(tetrahydrogen triphosphate)::uridine 5'-triphosphoric acid P2Y purinoceptor 4 Homo sapiens 480 ChEMBL 10.1021/jm2013198 10.7270/Q2Z60PJT 22107038 Yelovitch, S; Camden, J; Weisman, GA; Fischer, B Bar-Ilan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118213&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search UTP 6133 104011550 15713 CHEMBL336296 1734 C03517 ZINC19796107 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 51015861 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C9H15N2O15P3/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1 PGAVKCOVUIYSFO-XVFCMESISA-N 50118213 5'-UTP::CHEMBL336296::H4utp::UTP::uridine 5'-(tetrahydrogen triphosphate)::uridine 5'-triphosphoric acid P2Y purinoceptor 4 Homo sapiens 90 ChEMBL 10.1021/jm100287t 10.7270/Q2RB74SH 20446735 Maruoka, H; Barrett, MO; Ko, H; Tosh, DK; Melman, A; Burianek, LE; Balasubramanian, R; Berk, B; Costanzi, S; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118213&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search UTP 6133 104011550 15713 CHEMBL336296 1734 C03517 ZINC19796107 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 51029187 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C9H15N2O15P3/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1 PGAVKCOVUIYSFO-XVFCMESISA-N 50118213 5'-UTP::CHEMBL336296::H4utp::UTP::uridine 5'-(tetrahydrogen triphosphate)::uridine 5'-triphosphoric acid P2Y purinoceptor 4 Homo sapiens 900 ChEMBL 10.1016/j.bmc.2012.07.042 10.7270/Q21837S1 22901672 Ginsburg-Shmuel, T; Haas, M; Grbic, D; Arguin, G; Nadel, Y; Gendron, FP; Reiser, G; Fischer, B Bar-Ilan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118213&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search UTP 6133 104011550 15713 CHEMBL336296 1734 C03517 ZINC19796107 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738767 CCc1ccccc1Nc1cc(c(N)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C22H18N2O5S/c1-2-12-7-3-6-10-15(12)24-16-11-17(30(27,28)29)20(23)19-18(16)21(25)13-8-4-5-9-14(13)22(19)26/h3-11,24H,2,23H2,1H3,(H,27,28,29)/p-1 MKRYZWYODXUWEP-UHFFFAOYSA-M 50371702 CHEMBL402238 P2Y purinoceptor 4 Homo sapiens 3530 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50371702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50371702&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91930083 160850803 CHEMBL402238 ZINC29130947 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738768 CCc1cccc(Nc2cc(c(N)c3C(=O)c4ccccc4C(=O)c23)S([O-])(=O)=O)c1 InChI=1S/C22H18N2O5S/c1-2-12-6-5-7-13(10-12)24-16-11-17(30(27,28)29)20(23)19-18(16)21(25)14-8-3-4-9-15(14)22(19)26/h3-11,24H,2,23H2,1H3,(H,27,28,29)/p-1 OEEJYMAIKRMZLF-UHFFFAOYSA-M 50336790 CHEMBL1671993::Sodium 1-amino-4-(3-ethylphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 1510 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336790&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91932500 125086892 CHEMBL1671993 ZINC66065928 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738769 [Na+].CCCc1cccc(Nc2cc(c(N)c3C(=O)c4ccccc4C(=O)c23)S([O-])(=O)=O)c1 InChI=1S/C23H20N2O5S/c1-2-6-13-7-5-8-14(11-13)25-17-12-18(31(28,29)30)21(24)20-19(17)22(26)15-9-3-4-10-16(15)23(20)27/h3-5,7-12,25H,2,6,24H2,1H3,(H,28,29,30)/p-1 WLBSVGDJAHFOEG-UHFFFAOYSA-M 50237557 CHEMBL4063945 P2Y purinoceptor 4 Homo sapiens 2990 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50237557&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 137635546 385453538 CHEMBL4063945 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738770 COc1ccccc1Nc1cc(c(N)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C21H16N2O6S/c1-29-15-9-5-4-8-13(15)23-14-10-16(30(26,27)28)19(22)18-17(14)20(24)11-6-2-3-7-12(11)21(18)25/h2-10,23H,22H2,1H3,(H,26,27,28)/p-1 WCRXWKFBJBYISN-UHFFFAOYSA-M 50336767 CHEMBL257495::PSB-716::sodium 1-amino-4-(2-methoxyphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 3980 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336767 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336767&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 59448190 125086869 CHEMBL257495 ZINC29130857 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738771 COc1cccc(Nc2cc(c(N)c3C(=O)c4ccccc4C(=O)c23)S([O-])(=O)=O)c1 InChI=1S/C21H16N2O6S/c1-29-12-6-4-5-11(9-12)23-15-10-16(30(26,27)28)19(22)18-17(15)20(24)13-7-2-3-8-14(13)21(18)25/h2-10,23H,22H2,1H3,(H,26,27,28)/p-1 UOXSNOOWASRNHS-UHFFFAOYSA-M 50336768 CHEMBL1671995::sodium 1-amino-4-(3-methoxyphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 1700 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336768 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336768&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 59448192 125086870 CHEMBL1671995 ZINC33606789 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738772 Nc1c(cc(Nc2ccc(O)cc2)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C20H14N2O6S/c21-18-15(29(26,27)28)9-14(22-10-5-7-11(23)8-6-10)16-17(18)20(25)13-4-2-1-3-12(13)19(16)24/h1-9,22-23H,21H2,(H,26,27,28)/p-1 KFBGXLCLNATBFL-UHFFFAOYSA-M 50268725 CHEMBL496030::sodium 1-amino-4-(4-hydroxyphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 3160 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50268725 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50268725&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 59448191 104114982 CHEMBL496030 ZINC05162649 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738773 Nc1c(cc(Nc2ccccc2C(O)=O)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C21H14N2O7S/c22-18-15(31(28,29)30)9-14(23-13-8-4-3-7-12(13)21(26)27)16-17(18)20(25)11-6-2-1-5-10(11)19(16)24/h1-9,23H,22H2,(H,26,27)(H,28,29,30)/p-1 CRGRFFSHCCZVQW-UHFFFAOYSA-M 50268685 CHEMBL524064::sodium 1-amino-4-(2-carboxyphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 6100 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50268685 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50268685&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 59448159 104114971 CHEMBL524064 ZINC40953702 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738774 Nc1c(cc(Nc2ccc(cc2)C(O)=O)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C21H14N2O7S/c22-18-15(31(28,29)30)9-14(23-11-7-5-10(6-8-11)21(26)27)16-17(18)20(25)13-4-2-1-3-12(13)19(16)24/h1-9,23H,22H2,(H,26,27)(H,28,29,30)/p-1 QNQAEGCXDAVKAX-UHFFFAOYSA-M 50336775 CHEMBL604300::sodium 1-amino-4-(4-carboxyphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 30000 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336775&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 59448175 125086877 CHEMBL604300 ZINC45389821 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738775 Cc1cccc(Nc2cc(c(N)c3C(=O)c4ccccc4C(=O)c23)S([O-])(=O)=O)c1C InChI=1S/C22H18N2O5S/c1-11-6-5-9-15(12(11)2)24-16-10-17(30(27,28)29)20(23)19-18(16)21(25)13-7-3-4-8-14(13)22(19)26/h3-10,24H,23H2,1-2H3,(H,27,28,29)/p-1 KKWWXCGTSPOABZ-UHFFFAOYSA-M 50336791 CHEMBL402239::sodium 1-amino-4-(2,3-dimethylphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 2630 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336791&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91932501 125086893 CHEMBL402239 ZINC29130954 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738776 Cc1ccc(Nc2cc(c(N)c3C(=O)c4ccccc4C(=O)c23)S([O-])(=O)=O)c(C)c1 InChI=1S/C22H18N2O5S/c1-11-7-8-15(12(2)9-11)24-16-10-17(30(27,28)29)20(23)19-18(16)21(25)13-5-3-4-6-14(13)22(19)26/h3-10,24H,23H2,1-2H3,(H,27,28,29)/p-1 FYTJTDPRQJFSHH-UHFFFAOYSA-M 50336792 CHEMBL256688::sodium 1-amino-4-(2,4-dimethylphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 3580 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336792&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91932502 125086894 CHEMBL256688 ZINC29130950 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738777 [Na+].Cc1cc(C)cc(Nc2cc(c(N)c3C(=O)c4ccccc4C(=O)c23)S([O-])(=O)=O)c1 InChI=1S/C22H18N2O5S/c1-11-7-12(2)9-13(8-11)24-16-10-17(30(27,28)29)20(23)19-18(16)21(25)14-5-3-4-6-15(14)22(19)26/h3-10,24H,23H2,1-2H3,(H,27,28,29)/p-1 QNCHUZFQWQGZGX-UHFFFAOYSA-M 50237558 CHEMBL1671994 P2Y purinoceptor 4 Homo sapiens 6450 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50237558&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 53318846 385453539 CHEMBL1671994 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738778 [Na+].COc1ccc(Nc2cc(c(N)c3C(=O)c4ccccc4C(=O)c23)S([O-])(=O)=O)cc1OC InChI=1S/C22H18N2O7S/c1-30-15-8-7-11(9-16(15)31-2)24-14-10-17(32(27,28)29)20(23)19-18(14)21(25)12-5-3-4-6-13(12)22(19)26/h3-10,24H,23H2,1-2H3,(H,27,28,29)/p-1 JEBDYXUYQPCGII-UHFFFAOYSA-M 50237559 CHEMBL4063599 P2Y purinoceptor 4 Homo sapiens 4980 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237559 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50237559&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 137635749 385453540 CHEMBL4063599 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738779 COc1cc(Nc2cc(c(N)c3C(=O)c4ccccc4C(=O)c23)S([O-])(=O)=O)cc(OC)c1 InChI=1S/C22H18N2O7S/c1-30-12-7-11(8-13(9-12)31-2)24-16-10-17(32(27,28)29)20(23)19-18(16)21(25)14-5-3-4-6-15(14)22(19)26/h3-10,24H,23H2,1-2H3,(H,27,28,29)/p-1 UTSRSFVHJOAISY-UHFFFAOYSA-M 50336793 CHEMBL1671996::Sodium 1-amino-4-(3,5-dimethoxyphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 9250 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336793&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91932503 125086895 CHEMBL1671996 ZINC66074538 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738780 [Na+].Cc1cc(Cl)ccc1Nc1cc(c(N)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C21H15ClN2O5S/c1-10-8-11(22)6-7-14(10)24-15-9-16(30(27,28)29)19(23)18-17(15)20(25)12-4-2-3-5-13(12)21(18)26/h2-9,24H,23H2,1H3,(H,27,28,29)/p-1 VEHWEJIYNLSNHM-UHFFFAOYSA-M 50237560 CHEMBL4060811 P2Y purinoceptor 4 Homo sapiens 2200 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237560 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50237560&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 71531031 385453541 CHEMBL4060811 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738781 [Na+].Cc1cc(Nc2cc(c(N)c3C(=O)c4ccccc4C(=O)c23)S([O-])(=O)=O)ccc1Cl InChI=1S/C21H15ClN2O5S/c1-10-8-11(6-7-14(10)22)24-15-9-16(30(27,28)29)19(23)18-17(15)20(25)12-4-2-3-5-13(12)21(18)26/h2-9,24H,23H2,1H3,(H,27,28,29)/p-1 VIGDYRBYZHSJLY-UHFFFAOYSA-M 50237561 CHEMBL4082692 P2Y purinoceptor 4 Homo sapiens 1650 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237561 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50237561&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 137648855 385453542 CHEMBL4082692 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738782 [Na+].COc1cc(Nc2cc(c(N)c3C(=O)c4ccccc4C(=O)c23)S([O-])(=O)=O)ccc1F InChI=1S/C21H15FN2O6S/c1-30-15-8-10(6-7-13(15)22)24-14-9-16(31(27,28)29)19(23)18-17(14)20(25)11-4-2-3-5-12(11)21(18)26/h2-9,24H,23H2,1H3,(H,27,28,29)/p-1 LPYKJAHRITUHLJ-UHFFFAOYSA-M 50237562 CHEMBL4090513 P2Y purinoceptor 4 Homo sapiens 1540 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237562 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50237562&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 137644032 385453543 CHEMBL4090513 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738783 [Na+].COc1cc(Nc2cc(c(N)c3C(=O)c4ccccc4C(=O)c23)S([O-])(=O)=O)ccc1Cl InChI=1S/C21H15ClN2O6S/c1-30-15-8-10(6-7-13(15)22)24-14-9-16(31(27,28)29)19(23)18-17(14)20(25)11-4-2-3-5-12(11)21(18)26/h2-9,24H,23H2,1H3,(H,27,28,29)/p-1 VJSPZIKSYWLAFM-UHFFFAOYSA-M 50237563 CHEMBL4081964 P2Y purinoceptor 4 Homo sapiens 3370 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50237563&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 137647423 385453544 CHEMBL4081964 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738784 Nc1c(cc(Nc2cc(F)cc(F)c2)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C20H12F2N2O5S/c21-9-5-10(22)7-11(6-9)24-14-8-15(30(27,28)29)18(23)17-16(14)19(25)12-3-1-2-4-13(12)20(17)26/h1-8,24H,23H2,(H,27,28,29)/p-1 RWTLBALVZXOAHG-UHFFFAOYSA-M 50336795 CHEMBL1672099::Sodium 1-amino-4-(3,5-difluorophenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 12500 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336795 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336795&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91932505 125086897 CHEMBL1672099 ZINC66066275 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738785 Nc1c(cc(Nc2ccc(Cl)cc2C(O)=O)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C21H13ClN2O7S/c22-9-5-6-13(12(7-9)21(27)28)24-14-8-15(32(29,30)31)18(23)17-16(14)19(25)10-3-1-2-4-11(10)20(17)26/h1-8,24H,23H2,(H,27,28)(H,29,30,31)/p-1 AWDHCCPCIMVLNR-UHFFFAOYSA-M 50268767 CHEMBL524284::sodium 1-amino-4-(2-carboxy-4-chlorophenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50268767 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50268767&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 59448155 104114998 CHEMBL524284 ZINC04016165 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738786 [Na+].Nc1c(cc(Nc2ccc(Br)cc2C(O)=O)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C21H13BrN2O7S/c22-9-5-6-13(12(7-9)21(27)28)24-14-8-15(32(29,30)31)18(23)17-16(14)19(25)10-3-1-2-4-11(10)20(17)26/h1-8,24H,23H2,(H,27,28)(H,29,30,31)/p-1 UQBSXCLKYAVRBU-UHFFFAOYSA-M 50237565 CHEMBL603260 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237565 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50237565&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 46228816 385453545 CHEMBL603260 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738787 [Na+].Nc1c(cc(Nc2cccc(F)c2C(O)=O)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C21H13FN2O7S/c22-11-6-3-7-12(15(11)21(27)28)24-13-8-14(32(29,30)31)18(23)17-16(13)19(25)9-4-1-2-5-10(9)20(17)26/h1-8,24H,23H2,(H,27,28)(H,29,30,31)/p-1 ZWKKCBUYBTXINN-UHFFFAOYSA-M 50237566 CHEMBL4079524 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237566 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50237566&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 137651974 385453546 CHEMBL4079524 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738788 Nc1c(cc(Nc2cc(Cl)ccc2C(O)=O)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C21H13ClN2O7S/c22-9-5-6-12(21(27)28)13(7-9)24-14-8-15(32(29,30)31)18(23)17-16(14)19(25)10-3-1-2-4-11(10)20(17)26/h1-8,24H,23H2,(H,27,28)(H,29,30,31)/p-1 ROOPBYWMELIWRC-UHFFFAOYSA-M 50268768 CHEMBL522053::sodium 1-amino-4-(2-carboxy-5-chlorophenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 2760 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50268768 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50268768&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 59448156 104114999 CHEMBL522053 ZINC35300295 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738789 COc1cccc(Nc2cc(C)c(N)c3C(=O)c4ccccc4C(=O)c23)c1 InChI=1S/C22H18N2O3/c1-12-10-17(24-13-6-5-7-14(11-13)27-2)18-19(20(12)23)22(26)16-9-4-3-8-15(16)21(18)25/h3-11,24H,23H2,1-2H3 RWIHERISEREYPS-UHFFFAOYSA-N 50237569 CHEMBL4098596 P2Y purinoceptor 4 Homo sapiens >30000 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50237569&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 137659976 385453549 CHEMBL4098596 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738790 Cc1cccc(Nc2cc(c(N)c3C(=O)c4ccccc4C(=O)c23)S([O-])(=O)=O)c1 InChI=1S/C21H16N2O5S/c1-11-5-4-6-12(9-11)23-15-10-16(29(26,27)28)19(22)18-17(15)20(24)13-7-2-3-8-14(13)21(18)25/h2-10,23H,22H2,1H3,(H,26,27,28)/p-1 AYMOWRNYHLSUHI-UHFFFAOYSA-M 50336787 CHEMBL445413::sodium 1-amino-9,10-dioxo-4-(m-tolylamino)-9,10-dihydroanthracene-2-sulfonate::sodium 4-(m-toluidino)-1-amino-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 2220 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336787&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91932498 125086889 CHEMBL445413 ZINC29131032 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738794 Cc1ccc(Nc2cc(c(N)c3C(=O)c4ccccc4C(=O)c23)S([O-])(=O)=O)cc1 InChI=1S/C21H16N2O5S/c1-11-6-8-12(9-7-11)23-15-10-16(29(26,27)28)19(22)18-17(15)20(24)13-4-2-3-5-14(13)21(18)25/h2-10,23H,22H2,1H3,(H,26,27,28)/p-1 BSXYUOSITLGJAD-UHFFFAOYSA-M 50336788 CHEMBL404450::sodium 1-amino-9,10-dioxo-4-(p-tolylamino)-9,10-dihydroanthracene-2-sulfonate::sodium 4-(p-toluidino)-1-amino-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 2820 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336788&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 3362671 125086890 CHEMBL404450 ZINC04044209 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738796 Cc1ccccc1Nc1cc(c(N)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C21H16N2O5S/c1-11-6-2-5-9-14(11)23-15-10-16(29(26,27)28)19(22)18-17(15)20(24)12-7-3-4-8-13(12)21(18)25/h2-10,23H,22H2,1H3,(H,26,27,28)/p-1 IDRCEVKPWMZGEN-UHFFFAOYSA-M 50336786 CHEMBL256864::sodium 1-amino-9,10-dioxo-4-(o-tolylamino)-9,10-dihydroanthracene-2-sulfonate::sodium 4-(o-toluidino)-1-amino-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 3490 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336786&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91932497 125086888 CHEMBL256864 ZINC05161338 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738813 [Na+].Nc1c(cc(Nc2ccc(SCc3cccnc3)cc2)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C26H19N3O5S2/c27-24-21(36(32,33)34)12-20(22-23(24)26(31)19-6-2-1-5-18(19)25(22)30)29-16-7-9-17(10-8-16)35-14-15-4-3-11-28-13-15/h1-13,29H,14,27H2,(H,32,33,34)/p-1 JGUPAJPEKSBWAV-UHFFFAOYSA-M 50237573 CHEMBL4090874 P2Y purinoceptor 4 Homo sapiens 409 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50237573&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 137641946 385453553 CHEMBL4090874 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738815 [Na+].Cc1ccc(C)c(Sc2ccc(Nc3cc(c(N)c4C(=O)c5ccccc5C(=O)c34)S([O-])(=O)=O)cc2)c1 InChI=1S/C28H22N2O5S2/c1-15-7-8-16(2)22(13-15)36-18-11-9-17(10-12-18)30-21-14-23(37(33,34)35)26(29)25-24(21)27(31)19-5-3-4-6-20(19)28(25)32/h3-14,30H,29H2,1-2H3,(H,33,34,35)/p-1 KNEAPBAFQUQBSR-UHFFFAOYSA-M 50237574 CHEMBL4081274 P2Y purinoceptor 4 Homo sapiens 395 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50237574&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 137648798 385453554 CHEMBL4081274 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738816 Nc1c(cc(Nc2cccc(Br)c2)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C20H13BrN2O5S/c21-10-4-3-5-11(8-10)23-14-9-15(29(26,27)28)18(22)17-16(14)19(24)12-6-1-2-7-13(12)20(17)25/h1-9,23H,22H2,(H,26,27,28)/p-1 HTYPARFZJKMPJI-UHFFFAOYSA-M 50336772 CHEMBL1672098::sodium 1-amino-4-(3-bromophenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 6960 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336772 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336772&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 59448173 125086874 CHEMBL1672098 ZINC66066274 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738818 Nc1c(cc(Nc2ccc(Sc3ccccc3)cc2)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C26H18N2O5S2/c27-24-21(35(31,32)33)14-20(22-23(24)26(30)19-9-5-4-8-18(19)25(22)29)28-15-10-12-17(13-11-15)34-16-6-2-1-3-7-16/h1-14,28H,27H2,(H,31,32,33)/p-1 OBEHOHKAKLKSNL-UHFFFAOYSA-M 50268916 CHEMBL496620::Sodium 1-Amino-4-(4-phenylthiophenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 1180 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50268916 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50268916&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91935140 104115050 CHEMBL496620 ZINC40973232 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738819 Nc1c(cc(Nc2cccc(F)c2)c2C(=O)c3ccccc3C(=O)c12)S(O)(=O)=O InChI=1S/C20H13FN2O5S/c21-10-4-3-5-11(8-10)23-14-9-15(29(26,27)28)18(22)17-16(14)19(24)12-6-1-2-7-13(12)20(17)25/h1-9,23H,22H2,(H,26,27,28) XPJJVUHZNXODOA-UHFFFAOYSA-N 50237581 CHEMBL1741100 P2Y purinoceptor 4 Homo sapiens 30000 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237581 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50237581&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 51050133 385453561 CHEMBL1741100 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738821 [Na+].Nc1c(cc(Nc2ccc(O)cc2C(O)=O)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C21H14N2O8S/c22-18-15(32(29,30)31)8-14(23-13-6-5-9(24)7-12(13)21(27)28)16-17(18)20(26)11-4-2-1-3-10(11)19(16)25/h1-8,23-24H,22H2,(H,27,28)(H,29,30,31)/p-1 BVOFWVHPAOJBDJ-UHFFFAOYSA-M 50237583 CHEMBL4067679 P2Y purinoceptor 4 Homo sapiens 21100 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237583 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50237583&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 137631394 385453563 CHEMBL4067679 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738822 Cc1ccc(C)c(Nc2cc(c(N)c3C(=O)c4ccccc4C(=O)c23)S([O-])(=O)=O)c1 InChI=1S/C22H18N2O5S/c1-11-7-8-12(2)15(9-11)24-16-10-17(30(27,28)29)20(23)19-18(16)21(25)13-5-3-4-6-14(13)22(19)26/h3-10,24H,23H2,1-2H3,(H,27,28,29)/p-1 JSXNWKUMZUKQCQ-UHFFFAOYSA-M 50371703 CHEMBL256689 P2Y purinoceptor 4 Homo sapiens 11200 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50371703 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50371703&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91930084 160850804 CHEMBL256689 ZINC29130951 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738824 Nc1c(cc(Nc2ccc(Nc3nc(Cl)nc(Nc4cccc(c4)S([O-])(=O)=O)n3)c(c2)S([O-])(=O)=O)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C29H20ClN7O11S3/c30-27-35-28(33-13-4-3-5-15(10-13)49(40,41)42)37-29(36-27)34-18-9-8-14(11-20(18)50(43,44)45)32-19-12-21(51(46,47)48)24(31)23-22(19)25(38)16-6-1-2-7-17(16)26(23)39/h1-12,32H,31H2,(H,40,41,42)(H,43,44,45)(H,46,47,48)(H2,33,34,35,36,37)/p-3 JQYMGXZJTCOARG-UHFFFAOYSA-K 50029031 1-Amino-4-{4-[4-chloro-6-(3-sulfo-phenylamino)-[1,3,5]triazin-2-ylamino]-3-sulfo-phenylamino}-9,10-dioxo-9,10-dihydro-anthracene-2-sulfonic acid1-Amino-4-{4-[4-chloro-6-(4-sulfo-phenylamino)-[1,3,5]triazin-2-ylamino]-3-sulfo-phenylamino}-9,10-dioxo-9,10-dihydro-anthracene-2-sulfonic acid::CHEMBL223344::CID44285648::basilen blue::cibacron blue (mixer, meta and para isomers P2Y purinoceptor 4 Homo sapiens 1140 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029031&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 44285647 103938145 CHEMBL223344 C13746 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738826 [Na+].Nc1c(cc(Nc2ccccc2Cl)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C20H13ClN2O5S/c21-12-7-3-4-8-13(12)23-14-9-15(29(26,27)28)18(22)17-16(14)19(24)10-5-1-2-6-11(10)20(17)25/h1-9,23H,22H2,(H,26,27,28)/p-1 FCDNXKYADBFANH-UHFFFAOYSA-M 50237570 CHEMBL4084432 P2Y purinoceptor 4 Homo sapiens 9340 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50237570&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 137645875 385453550 CHEMBL4084432 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738829 Nc1c(cc(Nc2cccc(c2)C(O)=O)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C21H14N2O7S/c22-18-15(31(28,29)30)9-14(23-11-5-3-4-10(8-11)21(26)27)16-17(18)20(25)13-7-2-1-6-12(13)19(16)24/h1-9,23H,22H2,(H,26,27)(H,28,29,30)/p-1 DNGXTKJLUVIIRF-UHFFFAOYSA-M 50336774 CHEMBL598857::sodium 1-amino-4-(3-carboxyphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 23400 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336774&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 59448172 125086876 CHEMBL598857 ZINC13509468 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738830 [Na+].Cc1cc(Nc2cc(c(N)c3C(=O)c4ccccc4C(=O)c23)S([O-])(=O)=O)ccc1O InChI=1S/C21H16N2O6S/c1-10-8-11(6-7-15(10)24)23-14-9-16(30(27,28)29)19(22)18-17(14)20(25)12-4-2-3-5-13(12)21(18)26/h2-9,23-24H,22H2,1H3,(H,27,28,29)/p-1 XRIVZBSGEPKYFL-UHFFFAOYSA-M 50237576 CHEMBL4069492 P2Y purinoceptor 4 Homo sapiens 746 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50237576&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 137632198 385453556 CHEMBL4069492 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738831 Nc1c(cc(NCc2ccccc2)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C21H16N2O5S/c22-19-16(29(26,27)28)10-15(23-11-12-6-2-1-3-7-12)17-18(19)21(25)14-9-5-4-8-13(14)20(17)24/h1-10,23H,11,22H2,(H,26,27,28)/p-1 QNZLWFZNJCGPKX-UHFFFAOYSA-M 50268571 CHEMBL498223::Sodium 1-Amino-4-(benzylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 14400 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50268571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50268571&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91935116 104114920 CHEMBL498223 ZINC40425286 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738832 Nc1c2C(=O)c3ccccc3C(=O)c2c(Nc2ccccc2)cc1S([O-])(=O)=O InChI=1S/C20H14N2O5S/c21-18-15(28(25,26)27)10-14(22-11-6-2-1-3-7-11)16-17(18)20(24)13-9-5-4-8-12(13)19(16)23/h1-10,22H,21H2,(H,25,26,27)/p-1 OPBOOIFXQHPAPJ-UHFFFAOYSA-M 50227032 CHEMBL256057::acid blue 25::sodium 1-amino-9,10-dioxo-4-(phenylamino)-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 1970 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227032&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 7072970 104097288 CHEMBL256057 ZINC04016164 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738833 Nc1c(cc(NCCc2ccccc2)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C22H18N2O5S/c23-20-17(30(27,28)29)12-16(24-11-10-13-6-2-1-3-7-13)18-19(20)22(26)15-9-5-4-8-14(15)21(18)25/h1-9,12,24H,10-11,23H2,(H,27,28,29)/p-1 DERVVUPFXYMBNQ-UHFFFAOYSA-M 50268572 CHEMBL498224::Sodium 1-amino-4-(2-phenethylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate::sodium 1-amino-9,10-dioxo-4-(phenethylamino)-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 7180 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50268572 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50268572&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91935117 104114921 CHEMBL498224 ZINC40976294 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738835 Nc1c(cc(Nc2ccc(Cc3ccccc3)cc2)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C27H20N2O5S/c28-25-22(35(32,33)34)15-21(23-24(25)27(31)20-9-5-4-8-19(20)26(23)30)29-18-12-10-17(11-13-18)14-16-6-2-1-3-7-16/h1-13,15,29H,14,28H2,(H,32,33,34)/p-1 SZDMMMDMLDBHCB-UHFFFAOYSA-M 50268878 CHEMBL495605::Sodium 1-Amino-4-(4-benzylphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 3450 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50268878 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50268878&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91935139 104115036 CHEMBL495605 ZINC40953676 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738836 COc1ccc(Nc2cc(c(N)c3C(=O)c4ccccc4C(=O)c23)S([O-])(=O)=O)cc1 InChI=1S/C21H16N2O6S/c1-29-12-8-6-11(7-9-12)23-15-10-16(30(26,27)28)19(22)18-17(15)20(24)13-4-2-3-5-14(13)21(18)25/h2-10,23H,22H2,1H3,(H,26,27,28)/p-1 MURCBJRRFKMCAT-UHFFFAOYSA-M 50227023 1-amino-4-(4-methoxyphenyl)-2-sulfoanthraquinone::CHEMBL401735::SB-416::sodium 1-amino-4-(4-methoxyphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 2590 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227023&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 59448176 104097287 CHEMBL401735 ZINC29130859 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738839 [Na+].Nc1c2C(=O)c3ccccc3C(=O)c2c(Nc2ccc(Oc3ccc(Cl)cc3)cc2)cc1S([O-])(=O)=O InChI=1S/C26H17ClN2O6S/c27-14-5-9-16(10-6-14)35-17-11-7-15(8-12-17)29-20-13-21(36(32,33)34)24(28)23-22(20)25(30)18-3-1-2-4-19(18)26(23)31/h1-13,29H,28H2,(H,32,33,34)/p-1 QQHSLWIRLHGQRO-UHFFFAOYSA-M 50237575 CHEMBL4094930 P2Y purinoceptor 4 Homo sapiens 373 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237575 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50237575&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 137654771 385453555 CHEMBL4094930 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738840 Nc1c(cc(Nc2ccc(Br)cc2)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C20H13BrN2O5S/c21-10-5-7-11(8-6-10)23-14-9-15(29(26,27)28)18(22)17-16(14)19(24)12-3-1-2-4-13(12)20(17)25/h1-9,23H,22H2,(H,26,27,28)/p-1 AUTSWDYUCALUAF-UHFFFAOYSA-M 50378648 CHEMBL599050 P2Y purinoceptor 4 Homo sapiens 3300 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378648 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378648&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91929989 160857731 CHEMBL599050 ZINC45358393 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738841 Nc1c(cc(Nc2ccc(F)cc2)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C20H13FN2O5S/c21-10-5-7-11(8-6-10)23-14-9-15(29(26,27)28)18(22)17-16(14)19(24)12-3-1-2-4-13(12)20(17)25/h1-9,23H,22H2,(H,26,27,28)/p-1 HCTWKQCCDOTHIE-UHFFFAOYSA-M 50336771 CHEMBL604158::sodium 1-amino-4-(4-fluorophenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 4040 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336771&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 59448182 125086873 CHEMBL604158 ZINC45392019 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738843 Cc1cc(Nc2ccc(F)cc2C(O)=O)c2C(=O)c3ccccc3C(=O)c2c1N InChI=1S/C22H15FN2O4/c1-10-8-16(25-15-7-6-11(23)9-14(15)22(28)29)17-18(19(10)24)21(27)13-5-3-2-4-12(13)20(17)26/h2-9,25H,24H2,1H3,(H,28,29) BULNEEBWYIZDTB-UHFFFAOYSA-N 50237585 CHEMBL4080560 P2Y purinoceptor 4 Homo sapiens 100000 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237585 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50237585&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 137648293 385453565 CHEMBL4080560 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738845 Nc1c(cc(Nc2ccc(Oc3ccccc3)cc2)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C26H18N2O6S/c27-24-21(35(31,32)33)14-20(22-23(24)26(30)19-9-5-4-8-18(19)25(22)29)28-15-10-12-17(13-11-15)34-16-6-2-1-3-7-16/h1-14,28H,27H2,(H,31,32,33)/p-1 LBWABNLVVJJHCX-UHFFFAOYSA-M 50336770 CHEMBL597203::Sodium 1-amino-4-(4-phenoxyphenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate::sodium 1-amino-9,10-dioxo-4-(4-phenoxyphenylamino)-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 1940 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336770 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336770&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91932494 125086872 CHEMBL597203 ZINC45355160 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738846 Nc1c2C(=O)c3ccccc3C(=O)c2c(Nc2cccc3ccccc23)cc1S([O-])(=O)=O InChI=1S/C24H16N2O5S/c25-22-19(32(29,30)31)12-18(26-17-11-5-7-13-6-1-2-8-14(13)17)20-21(22)24(28)16-10-4-3-9-15(16)23(20)27/h1-12,26H,25H2,(H,29,30,31)/p-1 ZHQRPIRGSWEALJ-UHFFFAOYSA-M 50268574 CHEMBL498423::Sodium 1-Amino-4-(1-naphthylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate::Sodium 1-amino-4-[1-naphthylamino]-9,10-dioxo-9,10 dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 7420 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50268574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50268574&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 24868314 104114923 CHEMBL498423 ZINC13831235 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738847 Nc1c(cc(Nc2ccc(F)cc2C(O)=O)c2C(=O)c3ccccc3C(=O)c12)S(O)(=O)=O InChI=1S/C21H13FN2O7S/c22-9-5-6-13(12(7-9)21(27)28)24-14-8-15(32(29,30)31)18(23)17-16(14)19(25)10-3-1-2-4-11(10)20(17)26/h1-8,24H,23H2,(H,27,28)(H,29,30,31) OBFSYBSKXOCXQH-UHFFFAOYSA-N 50237584 CHEMBL1208510 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237584 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50237584&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 45141594 385453564 CHEMBL1208510 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738848 [Na+].COc1cc(Nc2cc(c(N)c3C(=O)c4ccccc4C(=O)c23)S([O-])(=O)=O)ccc1C InChI=1S/C22H18N2O6S/c1-11-7-8-12(9-16(11)30-2)24-15-10-17(31(27,28)29)20(23)19-18(15)21(25)13-5-3-4-6-14(13)22(19)26/h3-10,24H,23H2,1-2H3,(H,27,28,29)/p-1 YILXLDXCALMCFG-UHFFFAOYSA-M 50237582 CHEMBL4072198 P2Y purinoceptor 4 Homo sapiens 4130 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237582 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50237582&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 137639602 385453562 CHEMBL4072198 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738857 Nc1c(cc(Nc2ccc(Nc3nc(Cl)nc(Nc4ccc(cc4)S([O-])(=O)=O)n3)c(c2)S([O-])(=O)=O)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C29H20ClN7O11S3/c30-27-35-28(33-13-5-8-15(9-6-13)49(40,41)42)37-29(36-27)34-18-10-7-14(11-20(18)50(43,44)45)32-19-12-21(51(46,47)48)24(31)23-22(19)25(38)16-3-1-2-4-17(16)26(23)39/h1-12,32H,31H2,(H,40,41,42)(H,43,44,45)(H,46,47,48)(H2,33,34,35,36,37)/p-3 IYZXGLGVLYBKAI-UHFFFAOYSA-K 50029028 (cibacron blue,para isomer)1-Amino-4-{4-[4-chloro-6-(4-sulfo-phenylamino)-[1,3,5]triazin-2-ylamino]-3-sulfo-phenylamino}-9,10-dioxo-9,10-dihydro-anthracene-2-sulfonic acid P2Y purinoceptor 4 Homo sapiens 625 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029028&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 3638736 103938142 ZINC08035172 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738863 Nc1c(cc(Nc2cccc(F)c2)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C20H13FN2O5S/c21-10-4-3-5-11(8-10)23-14-9-15(29(26,27)28)18(22)17-16(14)19(24)12-6-1-2-7-13(12)20(17)25/h1-9,23H,22H2,(H,26,27,28)/p-1 XPJJVUHZNXODOA-UHFFFAOYSA-M 50336794 CHEMBL1671997::Sodium 1-amino-4-(3-flourophenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 1390 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336794&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91932504 125086896 CHEMBL1671997 ZINC66074518 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738879 [Na+].Nc1c(cc(Nc2cc(F)ccc2C(O)=O)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C21H13FN2O7S/c22-9-5-6-12(21(27)28)13(7-9)24-14-8-15(32(29,30)31)18(23)17-16(14)19(25)10-3-1-2-4-11(10)20(17)26/h1-8,24H,23H2,(H,27,28)(H,29,30,31)/p-1 VXOKFGIBXXFYOE-UHFFFAOYSA-M 50237578 CHEMBL603678 P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50237578&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 45141778 385453558 CHEMBL603678 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738896 Nc1c2C(=O)c3ccccc3C(=O)c2c(Nc2ccc(Nc3ccccc3)cc2)cc1S([O-])(=O)=O InChI=1S/C26H19N3O5S/c27-24-21(35(32,33)34)14-20(22-23(24)26(31)19-9-5-4-8-18(19)25(22)30)29-17-12-10-16(11-13-17)28-15-6-2-1-3-7-15/h1-14,28-29H,27H2,(H,32,33,34)/p-1 SLKPUOMONGLJQP-UHFFFAOYSA-M 50227016 CHEMBL401859::Sodium 1-amino-4-(4-anilinophenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate::sodium 1-amino-9,10-dioxo-4-(4-(phenylamino)phenylamino)-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 1910 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227016 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227016&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91935664 104097283 CHEMBL401859 ZINC29130725 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738907 [Na+].Cc1ccc(Sc2ccc(Nc3cc(c(N)c4C(=O)c5ccccc5C(=O)c34)S([O-])(=O)=O)cc2)cc1C InChI=1S/C28H22N2O5S2/c1-15-7-10-19(13-16(15)2)36-18-11-8-17(9-12-18)30-22-14-23(37(33,34)35)26(29)25-24(22)27(31)20-5-3-4-6-21(20)28(25)32/h3-14,30H,29H2,1-2H3,(H,33,34,35)/p-1 QXOGPTXQGKQSJT-UHFFFAOYSA-M 50237587 CHEMBL4099292 P2Y purinoceptor 4 Homo sapiens 482 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237587 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50237587&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 132574706 385453567 CHEMBL4099292 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738911 [Na+].Nc1c2C(=O)c3ccccc3C(=O)c2c(Nc2ccc(cc2C(O)=O)[N+]([O-])=O)cc1S([O-])(=O)=O InChI=1S/C21H13N3O9S/c22-18-15(34(31,32)33)8-14(23-13-6-5-9(24(29)30)7-12(13)21(27)28)16-17(18)20(26)11-4-2-1-3-10(11)19(16)25/h1-8,23H,22H2,(H,27,28)(H,31,32,33)/p-1 YVKRFSKUBIPTLX-UHFFFAOYSA-M 50237579 CHEMBL4095092 P2Y purinoceptor 4 Homo sapiens >30000 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237579 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50237579&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 137654054 385453559 CHEMBL4095092 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738919 Nc1c(cc(Nc2cccc(Cl)c2)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C20H13ClN2O5S/c21-10-4-3-5-11(8-10)23-14-9-15(29(26,27)28)18(22)17-16(14)19(24)12-6-1-2-7-13(12)20(17)25/h1-9,23H,22H2,(H,26,27,28)/p-1 NTYGNNJMCYGTJX-UHFFFAOYSA-M 50227020 CHEMBL271672::sodium 1-amino-4-(3-chlorophenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 2340 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227020&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 59448189 104097286 CHEMBL271672 ZINC29130781 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738920 Nc1c(cc(Nc2ccc(Cl)cc2)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C20H13ClN2O5S/c21-10-5-7-11(8-6-10)23-14-9-15(29(26,27)28)18(22)17-16(14)19(24)12-3-1-2-4-13(12)20(17)25/h1-9,23H,22H2,(H,26,27,28)/p-1 MHSMKEQLFFWYOS-UHFFFAOYSA-M 50227019 CHEMBL271673::sodium 1-amino-4-(4-chlorophenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens 3030 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227019&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 24868312 104097285 CHEMBL271673 ZINC13831234 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738922 [Na+].Nc1c2C(=O)c3ccccc3C(=O)c2c(Nc2ccc(Oc3ccc(F)cc3)cc2)cc1S([O-])(=O)=O InChI=1S/C26H17FN2O6S/c27-14-5-9-16(10-6-14)35-17-11-7-15(8-12-17)29-20-13-21(36(32,33)34)24(28)23-22(20)25(30)18-3-1-2-4-19(18)26(23)31/h1-13,29H,28H2,(H,32,33,34)/p-1 ZJMIBWMUXSTXHI-UHFFFAOYSA-M 50237580 CHEMBL4074456 P2Y purinoceptor 4 Homo sapiens 1690 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237580 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50237580&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 137640480 385453560 CHEMBL4074456 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738923 [Na+].CCc1ccc(Nc2cc(c(N)c3C(=O)c4ccccc4C(=O)c23)S([O-])(=O)=O)cc1 InChI=1S/C22H18N2O5S/c1-2-12-7-9-13(10-8-12)24-16-11-17(30(27,28)29)20(23)19-18(16)21(25)14-5-3-4-6-15(14)22(19)26/h3-11,24H,2,23H2,1H3,(H,27,28,29)/p-1 QZBPBRSWGHHNKJ-UHFFFAOYSA-M 50237586 CHEMBL4078095 P2Y purinoceptor 4 Homo sapiens 3210 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237586 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50237586&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 56944330 385453566 CHEMBL4078095 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738925 COc1cccc(Nc2cc(c(N)c3C(=O)c4ccccc4C(=O)c23)S(O)(=O)=O)c1 InChI=1S/C21H16N2O6S/c1-29-12-6-4-5-11(9-12)23-15-10-16(30(26,27)28)19(22)18-17(15)20(24)13-7-2-3-8-14(13)21(18)25/h2-10,23H,22H2,1H3,(H,26,27,28) UOXSNOOWASRNHS-UHFFFAOYSA-N 50237571 CHEMBL1741070 P2Y purinoceptor 4 Homo sapiens >10000 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50237571&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 3018777 385453551 CHEMBL1741070 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738926 Nc1c(cc(Nc2ccc(F)cc2C(O)=O)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O InChI=1S/C21H13FN2O7S/c22-9-5-6-13(12(7-9)21(27)28)24-14-8-15(32(29,30)31)18(23)17-16(14)19(25)10-3-1-2-4-11(10)20(17)26/h1-8,24H,23H2,(H,27,28)(H,29,30,31)/p-1 OBFSYBSKXOCXQH-UHFFFAOYSA-M 50307835 CHEMBL590956::Sodium 1-amino-4-[4-fluoro-2-carboxyphenylamino]-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate P2Y purinoceptor 4 Homo sapiens >100000 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50307835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50307835&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 91934095 104162196 CHEMBL590956 ZINC45335732 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738927 [Na+].Cc1ccc(Sc2ccc(Nc3cc(c(N)c4C(=O)c5ccccc5C(=O)c34)S([O-])(=O)=O)cc2)c(C)c1 InChI=1S/C28H22N2O5S2/c1-15-7-12-22(16(2)13-15)36-18-10-8-17(9-11-18)30-21-14-23(37(33,34)35)26(29)25-24(21)27(31)19-5-3-4-6-20(19)28(25)32/h3-14,30H,29H2,1-2H3,(H,33,34,35)/p-1 MHNSICQXIMKCDK-UHFFFAOYSA-M 50237577 CHEMBL4087247 P2Y purinoceptor 4 Homo sapiens 233 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50237577&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 137643396 385453557 CHEMBL4087247 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738930 [Na+].Nc1c2C(=O)c3ccccc3C(=O)c2c(Nc2ccc(Oc3ccc(Br)cc3)cc2)cc1S([O-])(=O)=O InChI=1S/C26H17BrN2O6S/c27-14-5-9-16(10-6-14)35-17-11-7-15(8-12-17)29-20-13-21(36(32,33)34)24(28)23-22(20)25(30)18-3-1-2-4-19(18)26(23)31/h1-13,29H,28H2,(H,32,33,34)/p-1 ZUVMPTRKHFZSQK-UHFFFAOYSA-M 50237572 CHEMBL4065831 P2Y purinoceptor 4 Homo sapiens 1760 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237572 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50237572&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 137633744 385453552 CHEMBL4065831 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 50738932 Cc1cc(Nc2cccc(F)c2)c2C(=O)c3ccccc3C(=O)c2c1N InChI=1S/C21H15FN2O2/c1-11-9-16(24-13-6-4-5-12(22)10-13)17-18(19(11)23)21(26)15-8-3-2-7-14(15)20(17)25/h2-10,24H,23H2,1H3 OTAPRFKQDKDOES-UHFFFAOYSA-N 50237568 CHEMBL4069875 P2Y purinoceptor 4 Homo sapiens >30000 ChEMBL 10.1021/acs.jmedchem.7b00030 10.7270/Q2G73H15 28306255 Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50237568&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 137639206 385453548 CHEMBL4069875 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 51209271 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cc\c(=N\OCc2ccc(Br)cc2)[nH]c1=O InChI=1S/C16H20BrN3O12P2/c17-10-3-1-9(2-4-10)7-29-19-12-5-6-20(16(23)18-12)15-14(22)13(21)11(31-15)8-30-34(27,28)32-33(24,25)26/h1-6,11,13-15,21-22H,7-8H2,(H,27,28)(H,18,19,23)(H2,24,25,26)/t11-,13-,14-,15-/m1/s1 IWXAQKCGEZAJBX-NMFUWQPSSA-N 50496855 CHEMBL3220048 P2Y purinoceptor 4 Homo sapiens 7440 ChEMBL 10.1039/c3md00132f 10.7270/Q20G3P36 26161252 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Kozma, E; Costanzi, S; Squarcialupi, L; Balasubramanian, R; Maruoka, H; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50496855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50496855&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 90666791 433964120 C03517 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 51209276 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cc\c(=N\OCc2ccc(cc2)[N+]([O-])=O)[nH]c1=O InChI=1S/C16H20N4O14P2/c21-13-11(8-32-36(29,30)34-35(26,27)28)33-15(14(13)22)19-6-5-12(17-16(19)23)18-31-7-9-1-3-10(4-2-9)20(24)25/h1-6,11,13-15,21-22H,7-8H2,(H,29,30)(H,17,18,23)(H2,26,27,28)/t11-,13-,14-,15-/m1/s1 HFBYGNURQMHJFJ-NMFUWQPSSA-N 50496858 CHEMBL3220050 P2Y purinoceptor 4 Homo sapiens 2200 ChEMBL 10.1039/c3md00132f 10.7270/Q20G3P36 26161252 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Kozma, E; Costanzi, S; Squarcialupi, L; Balasubramanian, R; Maruoka, H; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50496858 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50496858&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 90666793 433964123 C03517 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 51209292 CO\N=c1/ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)[nH]1 InChI=1S/C10H18N3O15P3/c1-24-12-6-2-3-13(10(16)11-6)9-8(15)7(14)5(26-9)4-25-30(20,21)28-31(22,23)27-29(17,18)19/h2-3,5,7-9,14-15H,4H2,1H3,(H,20,21)(H,22,23)(H,11,12,16)(H2,17,18,19)/t5-,7-,8-,9-/m1/s1 JFCPDJMYRHCAHH-ZOQUXTDFSA-N 50496860 CHEMBL1198849 P2Y purinoceptor 4 Homo sapiens 25 ChEMBL 10.1039/c3md00132f 10.7270/Q20G3P36 26161252 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Kozma, E; Costanzi, S; Squarcialupi, L; Balasubramanian, R; Maruoka, H; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50496860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50496860&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 46831692 433964125 C03517 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 51209293 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cc\c(=N\OCc2cccc(I)c2)[nH]c1=O InChI=1S/C16H20IN3O12P2/c17-10-3-1-2-9(6-10)7-29-19-12-4-5-20(16(23)18-12)15-14(22)13(21)11(31-15)8-30-34(27,28)32-33(24,25)26/h1-6,11,13-15,21-22H,7-8H2,(H,27,28)(H,18,19,23)(H2,24,25,26)/t11-,13-,14-,15-/m1/s1 VFLQFYSBULVBTG-NMFUWQPSSA-N 50496856 CHEMBL3220047 P2Y purinoceptor 4 Homo sapiens 352 ChEMBL 10.1039/c3md00132f 10.7270/Q20G3P36 26161252 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Kozma, E; Costanzi, S; Squarcialupi, L; Balasubramanian, R; Maruoka, H; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50496856 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50496856&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 90666790 433964121 C03517 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 51209294 CO\N=c1\ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n3ccc(=O)[nH]c3=O)[C@@H](O)[C@H]2O)c(=O)[nH]1 InChI=1S/C19H28N5O20P3/c1-38-22-10-2-4-23(18(30)20-10)16-14(28)12(26)8(41-16)6-39-45(32,33)43-47(36,37)44-46(34,35)40-7-9-13(27)15(29)17(42-9)24-5-3-11(25)21-19(24)31/h2-5,8-9,12-17,26-29H,6-7H2,1H3,(H,32,33)(H,34,35)(H,36,37)(H,20,22,30)(H,21,25,31)/t8-,9-,12-,13-,14-,15-,16-,17-/m1/s1 SIKKMGJHOOQSAP-RTGFKBDUSA-N 50496853 CHEMBL1198754 P2Y purinoceptor 4 Homo sapiens 790 ChEMBL 10.1039/c3md00132f 10.7270/Q20G3P36 26161252 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Kozma, E; Costanzi, S; Squarcialupi, L; Balasubramanian, R; Maruoka, H; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50496853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50496853&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 46830491 433964118 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 51209295 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cc\c(=N\OCc2ccccc2)[nH]c1=O InChI=1S/C16H21N3O12P2/c20-13-11(9-29-33(26,27)31-32(23,24)25)30-15(14(13)21)19-7-6-12(17-16(19)22)18-28-8-10-4-2-1-3-5-10/h1-7,11,13-15,20-21H,8-9H2,(H,26,27)(H,17,18,22)(H2,23,24,25)/t11-,13-,14-,15-/m1/s1 YNDKQBMZPIWHEC-NMFUWQPSSA-N 50496854 CHEMBL1198872 P2Y purinoceptor 4 Homo sapiens 1150 ChEMBL 10.1039/c3md00132f 10.7270/Q20G3P36 26161252 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Kozma, E; Costanzi, S; Squarcialupi, L; Balasubramanian, R; Maruoka, H; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50496854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50496854&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 46831686 433964119 C03517 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 51209296 CC(=O)NCCn1cc(CCOP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cc\c(=N\OCc3ccccc3)[nH]c2=O)nn1 InChI=1S/C24H34N7O16P3/c1-16(32)25-9-11-30-13-18(27-29-30)8-12-43-48(36,37)46-50(40,41)47-49(38,39)44-15-19-21(33)22(34)23(45-19)31-10-7-20(26-24(31)35)28-42-14-17-5-3-2-4-6-17/h2-7,10,13,19,21-23,33-34H,8-9,11-12,14-15H2,1H3,(H,25,32)(H,36,37)(H,38,39)(H,40,41)(H,26,28,35)/t19-,21-,22-,23-/m1/s1 RYWQVZLIGJOUIY-JMJGKCIBSA-N 50496864 CHEMBL3220058 P2Y purinoceptor 4 Homo sapiens 3300 ChEMBL 10.1039/c3md00132f 10.7270/Q20G3P36 26161252 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Kozma, E; Costanzi, S; Squarcialupi, L; Balasubramanian, R; Maruoka, H; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50496864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50496864&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 90666802 433964129 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 51209303 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(NOCc2ccccc2)nc1=O InChI=1S/C16H22N3O15P3/c20-13-11(9-31-36(26,27)34-37(28,29)33-35(23,24)25)32-15(14(13)21)19-7-6-12(17-16(19)22)18-30-8-10-4-2-1-3-5-10/h1-7,11,13-15,20-21H,8-9H2,(H,26,27)(H,28,29)(H,17,18,22)(H2,23,24,25)/t11-,13-,14-,15-/m1/s1 BQIJGMRNEJCCQG-NMFUWQPSSA-N 50345484 CHEMBL1784892::N4-Benzyloxycytidine-5'-triphosphate P2Y purinoceptor 4 Homo sapiens 97 ChEMBL 10.1039/c3md00132f 10.7270/Q20G3P36 26161252 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Kozma, E; Costanzi, S; Squarcialupi, L; Balasubramanian, R; Maruoka, H; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345484&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 53308272 131348415 CHEMBL1784892 C03517 ZINC71282457 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 51209304 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cc\c(=N\OCc2cccc(c2)C#CCCC#C)[nH]c1=O InChI=1S/C22H25N3O12P2/c1-2-3-4-5-7-15-8-6-9-16(12-15)13-34-24-18-10-11-25(22(28)23-18)21-20(27)19(26)17(36-21)14-35-39(32,33)37-38(29,30)31/h1,6,8-12,17,19-21,26-27H,3-4,13-14H2,(H,32,33)(H,23,24,28)(H2,29,30,31)/t17-,19-,20-,21-/m1/s1 HBDLPKDBEOEVAO-CWJKEVGVSA-N 50496862 CHEMBL3220051 P2Y purinoceptor 4 Homo sapiens 952 ChEMBL 10.1039/c3md00132f 10.7270/Q20G3P36 26161252 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Kozma, E; Costanzi, S; Squarcialupi, L; Balasubramanian, R; Maruoka, H; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50496862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50496862&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 90666794 433964127 C03517 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 51209305 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cc\c(=N\OCc2cccc(Br)c2)[nH]c1=O InChI=1S/C16H20BrN3O12P2/c17-10-3-1-2-9(6-10)7-29-19-12-4-5-20(16(23)18-12)15-14(22)13(21)11(31-15)8-30-34(27,28)32-33(24,25)26/h1-6,11,13-15,21-22H,7-8H2,(H,27,28)(H,18,19,23)(H2,24,25,26)/t11-,13-,14-,15-/m1/s1 FGMXILSWRVITJV-NMFUWQPSSA-N 50496857 CHEMBL3220046 P2Y purinoceptor 4 Homo sapiens >10000 ChEMBL 10.1039/c3md00132f 10.7270/Q20G3P36 26161252 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Kozma, E; Costanzi, S; Squarcialupi, L; Balasubramanian, R; Maruoka, H; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50496857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50496857&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 90666789 433964122 C03517 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 51209307 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cc\c(=N\OCc3ccccc3)[nH]c2=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C25H32N5O20P3/c31-17-7-9-30(25(37)27-17)23-21(35)19(33)15(48-23)12-46-52(40,41)50-53(42,43)49-51(38,39)45-11-14-18(32)20(34)22(47-14)29-8-6-16(26-24(29)36)28-44-10-13-4-2-1-3-5-13/h1-9,14-15,18-23,32-35H,10-12H2,(H,38,39)(H,40,41)(H,42,43)(H,26,28,36)(H,27,31,37)/t14-,15-,18-,19-,20-,21-,22-,23-/m1/s1 PAOIUUIZGOVIOK-XIZJPJQXSA-N 50496861 CHEMBL3220054 P2Y purinoceptor 4 Homo sapiens 636 ChEMBL 10.1039/c3md00132f 10.7270/Q20G3P36 26161252 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Kozma, E; Costanzi, S; Squarcialupi, L; Balasubramanian, R; Maruoka, H; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50496861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50496861&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 90666798 433964126 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 51209309 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C18H25N4O20P3/c23-9-1-3-21(17(29)19-9)15-13(27)11(25)7(39-15)5-37-43(31,32)41-45(35,36)42-44(33,34)38-6-8-12(26)14(28)16(40-8)22-4-2-10(24)20-18(22)30/h1-4,7-8,11-16,25-28H,5-6H2,(H,31,32)(H,33,34)(H,35,36)(H,19,23,29)(H,20,24,30)/t7-,8-,11-,12-,13-,14-,15-,16-/m1/s1 JPNWHMPVXHYIKN-NCOIDOBVSA-N 50241299 CHEMBL239151::{[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphinic acid P2Y purinoceptor 4 Homo sapiens 870 ChEMBL 10.1039/c3md00132f 10.7270/Q20G3P36 26161252 Jayasekara, PS; Barrett, MO; Ball, CB; Brown, KA; Kozma, E; Costanzi, S; Squarcialupi, L; Balasubramanian, R; Maruoka, H; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241299&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 9875011 104098700 CHEMBL239151 ZINC49946842 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 51314478 OC(=O)c1cc(-c2ccc(cc2)C2CCNCC2)c2ccc(cc2c1)-c1ccc(cc1)C(F)(F)F InChI=1S/C29H24F3NO2/c30-29(31,32)25-8-5-19(6-9-25)22-7-10-26-23(15-22)16-24(28(34)35)17-27(26)21-3-1-18(2-4-21)20-11-13-33-14-12-20/h1-10,15-17,20,33H,11-14H2,(H,34,35) FOECKIWHCOYYFL-UHFFFAOYSA-N 50456168 CHEMBL1800685 P2Y purinoceptor 4 Homo sapiens >10000 ChEMBL 10.1021/acs.jmedchem.6b00044 10.7270/Q2DJ5K34 27331270 Junker, A; Balasubramanian, R; Ciancetta, A; Uliassi, E; Kiselev, E; Martiriggiano, C; Trujillo, K; Mtchedlidze, G; Birdwell, L; Brown, KA; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50456168 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50456168&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 42611190 225147084 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 51314486 OC(=O)c1cc(-c2ccc(cc2)C2CCNCC2)c2ccc(cc2c1)-c1ccc(cc1)C(F)(F)F InChI=1S/C29H24F3NO2/c30-29(31,32)25-8-5-19(6-9-25)22-7-10-26-23(15-22)16-24(28(34)35)17-27(26)21-3-1-18(2-4-21)20-11-13-33-14-12-20/h1-10,15-17,20,33H,11-14H2,(H,34,35) FOECKIWHCOYYFL-UHFFFAOYSA-N 50456168 CHEMBL1800685 P2Y purinoceptor 4 Homo sapiens >10000 ChEMBL 10.1021/acs.jmedchem.6b00044 10.7270/Q2DJ5K34 27331270 Junker, A; Balasubramanian, R; Ciancetta, A; Uliassi, E; Kiselev, E; Martiriggiano, C; Trujillo, K; Mtchedlidze, G; Birdwell, L; Brown, KA; Harden, TK; Jacobson, KA National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50456168 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50456168&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 42611190 225147084 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 51527094 O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O InChI=1S/C9H15N2O15P3/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1 PGAVKCOVUIYSFO-XVFCMESISA-N 50118213 5'-UTP::CHEMBL336296::H4utp::UTP::uridine 5'-(tetrahydrogen triphosphate)::uridine 5'-triphosphoric acid P2Y purinoceptor 4 Homo sapiens 550 ChEMBL 10.7270/Q2KD236Q 27413802 Conroy, S; Kindon, N; Kellam, B; Stocks, MJ University of Nottingham http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118213&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search UTP 6133 104011550 15713 CHEMBL336296 1734 C03517 ZINC19796107 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 51527095 Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O InChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1 ZKHQWZAMYRWXGA-KQYNXXCUSA-N 50366480 ADENOSINE TRIPHOSPHATE::ATP P2Y purinoceptor 4 Homo sapiens 6200 ChEMBL 10.7270/Q2KD236Q 27413802 Conroy, S; Kindon, N; Kellam, B; Stocks, MJ University of Nottingham http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366480&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search ATP 5957 160845582 15422 C03517 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 51494809 FC(F)(F)c1cc(NS(=O)(=O)c2cc3N(CCc3cc2Br)C(=O)C2CC2)ccc1Cl InChI=1S/C19H15BrClF3N2O3S/c20-14-7-11-5-6-26(18(27)10-1-2-10)16(11)9-17(14)30(28,29)25-12-3-4-15(21)13(8-12)19(22,23)24/h3-4,7-10,25H,1-2,5-6H2 OGXJZCDFFBDSJJ-UHFFFAOYSA-N 50602133 CHEMBL5191550 P2Y purinoceptor 4 Homo sapiens 13640 ChEMBL 10.7270/Q26D5Z20 36394994 Wang, YH; Zhou, MZ; Ye, T; Wang, PP; Lu, R; Wang, YL; Liu, CX; Xiao, W; Li, JY; Meng, ZB; Xu, LL; Hu, QH; Jiang, C China Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50602133 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50602133&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 46504926 482612984 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22 51494815 OC(=O)c1cc(-c2ccc(cc2)C2CCNCC2)c2ccc(cc2c1)-c1ccc(cc1)C(F)(F)F InChI=1S/C29H24F3NO2/c30-29(31,32)25-8-5-19(6-9-25)22-7-10-26-23(15-22)16-24(28(34)35)17-27(26)21-3-1-18(2-4-21)20-11-13-33-14-12-20/h1-10,15-17,20,33H,11-14H2,(H,34,35) FOECKIWHCOYYFL-UHFFFAOYSA-N 50456168 CHEMBL1800685 P2Y purinoceptor 4 Homo sapiens >10000 ChEMBL 10.7270/Q26D5Z20 36394994 Wang, YH; Zhou, MZ; Ye, T; Wang, PP; Lu, R; Wang, YL; Liu, CX; Xiao, W; Li, JY; Meng, ZB; Xu, LL; Hu, QH; Jiang, C China Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50456168 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000727&target=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50456168&enzyme=P2Y+purinoceptor+4&column=ki&startPg=0&Increment=50&submit=Search 42611190 225147084 1 MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL P2Y purinoceptor 4 P2RY4_HUMAN P51582 Q4VBB7 Q4VBB8 Q502W2 Q5JT22