BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 50036338 Nc1nc2c(c[nH]c2c(=O)[nH]1)C(CC#N)c1cccc(Cl)c1 InChI=1S/C15H12ClN5O/c16-9-3-1-2-8(6-9)10(4-5-17)11-7-19-13-12(11)20-15(18)21-14(13)22/h1-3,6-7,10,19H,4H2,(H3,18,20,21,22) OHFLESATPONDTK-UHFFFAOYSA-N 50039549 3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)-3-(3-chloro-phenyl)-propionitrile::CHEMBL81839 Purine nucleoside phosphorylase Rattus norvegicus 11 ChEMBL 10.1021/jm00041a027 10.7270/Q21G0K9T 8057293 Niwas, S; Chand, P; Pathak, VP; Montgomery, JA Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039549 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039549&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 19692440 103946746 CHEMBL81839 ZINC13738104 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50036339 Nc1nc2nc(N)[nH]c(=O)c2[nH]1 InChI=1S/C5H6N6O/c6-4-8-1-2(9-4)10-5(7)11-3(1)12/h(H6,6,7,8,9,10,11,12) WYDKPTZGVLTYPG-UHFFFAOYSA-N 50022243 2,8-Diamino-1,9-dihydro-purin-6-one::8-AMINOGUANINE::CHEMBL8040 Purine nucleoside phosphorylase Rattus norvegicus 100 ChEMBL 10.1021/jm00041a027 10.7270/Q21G0K9T 8057293 Niwas, S; Chand, P; Pathak, VP; Montgomery, JA Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50022243 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50022243&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 95201 103932866 CHEMBL8040 ZINC13514984 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50036340 O=c1[nH]cnc2c(Cc3ccsc3)c[nH]c12 InChI=1S/C11H9N3OS/c15-11-10-9(13-6-14-11)8(4-12-10)3-7-1-2-16-5-7/h1-2,4-6,12H,3H2,(H,13,14,15) DZRJGBKWVIJPOL-UHFFFAOYSA-N 50039556 7-Thiophen-3-ylmethyl-3,5-dihydro-pyrrolo[3,2-d]pyrimidin-4-one::CHEMBL81348 Purine nucleoside phosphorylase Rattus norvegicus 28 ChEMBL 10.1021/jm00041a027 10.7270/Q21G0K9T 8057293 Niwas, S; Chand, P; Pathak, VP; Montgomery, JA Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039556 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039556&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 10331461 103946753 CHEMBL81348 ZINC00019375 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50036341 O=c1[nH]cnc2c(CC3CCCC3)c[nH]c12 InChI=1S/C12H15N3O/c16-12-11-10(14-7-15-12)9(6-13-11)5-8-3-1-2-4-8/h6-8,13H,1-5H2,(H,14,15,16) LUYOAOZVQYOVFL-UHFFFAOYSA-N 50039553 7-Cyclopentylmethyl-3,5-dihydro-pyrrolo[3,2-d]pyrimidin-4-one::CHEMBL310458 Purine nucleoside phosphorylase Rattus norvegicus 29 ChEMBL 10.1021/jm00041a027 10.7270/Q21G0K9T 8057293 Niwas, S; Chand, P; Pathak, VP; Montgomery, JA Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039553 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039553&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 10082075 103946750 CHEMBL310458 ZINC00019374 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50036342 OP(O)(=O)CCCCCn1cnc2c1nc[nH]c2=O InChI=1S/C10H15N4O4P/c15-10-8-9(11-6-12-10)14(7-13-8)4-2-1-3-5-19(16,17)18/h6-7H,1-5H2,(H,11,12,15)(H2,16,17,18) HKVZDTLGAPBOBY-UHFFFAOYSA-N 50039555 CHEMBL13130::[5-(6-Oxo-1,6-dihydro-purin-9-yl)-pentyl]-phosphonic acid Purine nucleoside phosphorylase Rattus norvegicus 1000 ChEMBL 10.1021/jm00041a027 10.7270/Q21G0K9T 8057293 Niwas, S; Chand, P; Pathak, VP; Montgomery, JA Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039555 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039555&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 44268673 103946752 CHEMBL13130 ZINC13735751 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50036343 Nc1nc2c(nc[nH]c2=O)n1Cc1ccccc1 InChI=1S/C12H11N5O/c13-12-16-9-10(14-7-15-11(9)18)17(12)6-8-4-2-1-3-5-8/h1-5,7H,6H2,(H2,13,16)(H,14,15,18) UKSFYWIMCRRBDH-UHFFFAOYSA-N 50039543 8-Amino-9-benzyl-1,9-dihydro-purin-6-one::CHEMBL84493 Purine nucleoside phosphorylase Rattus norvegicus 150000 ChEMBL 10.1021/jm00041a027 10.7270/Q21G0K9T 8057293 Niwas, S; Chand, P; Pathak, VP; Montgomery, JA Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039543&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 44461537 103946741 CHEMBL84493 ZINC26500524 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50036344 O=c1[nH]cnc2c(Cc3cccc(OCc4ccccc4)c3)c[nH]c12 InChI=1S/C20H17N3O2/c24-20-19-18(22-13-23-20)16(11-21-19)9-15-7-4-8-17(10-15)25-12-14-5-2-1-3-6-14/h1-8,10-11,13,21H,9,12H2,(H,22,23,24) KPGUOANHRAPLEA-UHFFFAOYSA-N 50039558 7-(3-Benzyloxy-benzyl)-3,5-dihydro-pyrrolo[3,2-d]pyrimidin-4-one::CHEMBL84475 Purine nucleoside phosphorylase Rattus norvegicus 190 ChEMBL 10.1021/jm00041a027 10.7270/Q21G0K9T 8057293 Niwas, S; Chand, P; Pathak, VP; Montgomery, JA Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039558&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 10314632 103946755 CHEMBL84475 ZINC00019376 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50036345 Clc1cccc(c1)C(CC#N)c1c[nH]c2c1nc[nH]c2=O InChI=1S/C15H11ClN4O/c16-10-3-1-2-9(6-10)11(4-5-17)12-7-18-14-13(12)19-8-20-15(14)21/h1-3,6-8,11,18H,4H2,(H,19,20,21) USKRFMSFROSNJF-UHFFFAOYSA-N 50039561 3-(3-Chloro-phenyl)-3-(4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)-propionitrile::CHEMBL315570 Purine nucleoside phosphorylase Rattus norvegicus 10 ChEMBL 10.1021/jm00041a027 10.7270/Q21G0K9T 8057293 Niwas, S; Chand, P; Pathak, VP; Montgomery, JA Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039561 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039561&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 10357360 103946758 CHEMBL315570 ZINC13738103 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50036346 OCCCCn1cnc2c1nc[nH]c2=O InChI=1S/C9H12N4O2/c14-4-2-1-3-13-6-12-7-8(13)10-5-11-9(7)15/h5-6,14H,1-4H2,(H,10,11,15) BZOSXNLDTQTFOK-UHFFFAOYSA-N 50039560 9-(4-Hydroxy-butyl)-1,9-dihydro-purin-6-one::CHEMBL83421 Purine nucleoside phosphorylase Rattus norvegicus >200000 ChEMBL 10.1021/jm00041a027 10.7270/Q21G0K9T 8057293 Niwas, S; Chand, P; Pathak, VP; Montgomery, JA Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039560 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039560&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 362756 103946757 CHEMBL83421 ZINC08656001 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50036347 Nc1nc2c(CC3CCCC3)c[nH]c2c(=O)[nH]1 InChI=1S/C12H16N4O/c13-12-15-9-8(5-7-3-1-2-4-7)6-14-10(9)11(17)16-12/h6-7,14H,1-5H2,(H3,13,15,16,17) YFJGSWQEEMSQEI-UHFFFAOYSA-N 50039562 2-Amino-7-cyclopentylmethyl-3,5-dihydro-pyrrolo[3,2-d]pyrimidin-4-one::CHEMBL56593 Purine nucleoside phosphorylase Rattus norvegicus 29 ChEMBL 10.1021/jm00041a027 10.7270/Q21G0K9T 8057293 Niwas, S; Chand, P; Pathak, VP; Montgomery, JA Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039562 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039562&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 15646012 103946759 CHEMBL56593 ZINC13738105 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50036348 Nc1nc2c(Cc3cccc(OCc4ccccc4)c3)c[nH]c2c(=O)[nH]1 InChI=1S/C20H18N4O2/c21-20-23-17-15(11-22-18(17)19(25)24-20)9-14-7-4-8-16(10-14)26-12-13-5-2-1-3-6-13/h1-8,10-11,22H,9,12H2,(H3,21,23,24,25) VHZPIMFKLUZYKJ-UHFFFAOYSA-N 50039557 2-Amino-7-(3-benzyloxy-benzyl)-3,5-dihydro-pyrrolo[3,2-d]pyrimidin-4-one::CHEMBL83056 Purine nucleoside phosphorylase Rattus norvegicus 147 ChEMBL 10.1021/jm00041a027 10.7270/Q21G0K9T 8057293 Niwas, S; Chand, P; Pathak, VP; Montgomery, JA Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039557&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 10427725 103946754 CHEMBL83056 ZINC13738106 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50036349 Nc1nc2c(Cc3cccnc3)c[nH]c2c(=O)[nH]1 InChI=1S/C12H11N5O/c13-12-16-9-8(4-7-2-1-3-14-5-7)6-15-10(9)11(18)17-12/h1-3,5-6,15H,4H2,(H3,13,16,17,18) DOHVAKFYAHLCJP-UHFFFAOYSA-N 50039542 2-Amino-7-pyridin-3-ylmethyl-3,5-dihydro-pyrrolo[3,2-d]pyrimidin-4-one::2-amino-7-(pyridin-3-ylmethyl)-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one::2-amino-7-(pyridin-3-ylmethyl)-3H-pyrrolo[3,2-d]pyrimidin-4(5H)-one::CHEMBL311300 Purine nucleoside phosphorylase Rattus norvegicus 25 ChEMBL 10.1021/jm00041a027 10.7270/Q21G0K9T 8057293 Niwas, S; Chand, P; Pathak, VP; Montgomery, JA Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039542 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039542&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search BC3 3DJF 60817 103946740 CHEMBL311300 ZINC05420970 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50036350 CC(C)(CCn1cnc2c1nc(N)[nH]c2=O)CCP(O)(O)=O InChI=1S/C12H20N5O4P/c1-12(2,4-6-22(19,20)21)3-5-17-7-14-8-9(17)15-11(13)16-10(8)18/h7H,3-6H2,1-2H3,(H2,19,20,21)(H3,13,15,16,18) UYGTVQNSPBEEPR-UHFFFAOYSA-N 50039551 CHEMBL13448::[5-(2-Amino-6-oxo-1,6-dihydro-purin-9-yl)-3,3-dimethyl-pentyl]-phosphonic acid Purine nucleoside phosphorylase Rattus norvegicus 45 ChEMBL 10.1021/jm00041a027 10.7270/Q21G0K9T 8057293 Niwas, S; Chand, P; Pathak, VP; Montgomery, JA Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039551&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 192696 103946748 CHEMBL13448 ZINC31538469 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50036351 Nc1nc2nc[nH]c(=O)c2[nH]1 InChI=1S/C5H5N5O/c6-5-9-2-3(10-5)7-1-8-4(2)11/h1H,(H4,6,7,8,9,10,11) NVDXOOZGKFFGDJ-UHFFFAOYSA-N 50039554 8-Amino-1,7-dihydro-purin-6-one::CHEMBL83601 Purine nucleoside phosphorylase Rattus norvegicus 10000 ChEMBL 10.1021/jm00041a027 10.7270/Q21G0K9T 8057293 Niwas, S; Chand, P; Pathak, VP; Montgomery, JA Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039554 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039554&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 5243960 103946751 CHEMBL83601 ZINC04429564 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50036352 O=c1[nH]cnc2c(Cc3ccccc3)c[nH]c12 InChI=1S/C13H11N3O/c17-13-12-11(15-8-16-13)10(7-14-12)6-9-4-2-1-3-5-9/h1-5,7-8,14H,6H2,(H,15,16,17) XTZNEYRTGZTVGE-UHFFFAOYSA-N 50039548 7-Benzyl-3,5-dihydro-pyrrolo[3,2-d]pyrimidin-4-one::CHEMBL81055 Purine nucleoside phosphorylase Rattus norvegicus 35 ChEMBL 10.1021/jm00041a027 10.7270/Q21G0K9T 8057293 Niwas, S; Chand, P; Pathak, VP; Montgomery, JA Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039548 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039548&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 10353609 103946745 CHEMBL81055 ZINC00006234 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50036353 Nc1nc2n(CCCCO)cnc2c(=O)[nH]1 InChI=1S/C9H13N5O2/c10-9-12-7-6(8(16)13-9)11-5-14(7)3-1-2-4-15/h5,15H,1-4H2,(H3,10,12,13,16) DVQJDXCYEPGOCF-UHFFFAOYSA-N 21868 2-amino-9-(4-hydroxybutyl)-6,9-dihydro-3H-purin-6-one::9-(4-hydroxybutyl)guanine::CHEMBL258513::HBG Purine nucleoside phosphorylase Rattus norvegicus 77000 ChEMBL 10.1021/jm00041a027 10.7270/Q21G0K9T 8057293 Niwas, S; Chand, P; Pathak, VP; Montgomery, JA Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21868&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 161408 49700972 CHEMBL258513 ZINC06119296 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50036354 NC(Cn1cnc2c1nc[nH]c2=O)C(O)CO InChI=1S/C9H13N5O3/c10-5(6(16)2-15)1-14-4-13-7-8(14)11-3-12-9(7)17/h3-6,15-16H,1-2,10H2,(H,11,12,17) YMQWBLRLMCNGGN-UHFFFAOYSA-N 50039550 9-(2-Amino-3,4-dihydroxy-butyl)-1,9-dihydro-purin-6-one::CHEMBL79666 Purine nucleoside phosphorylase Rattus norvegicus >100000 ChEMBL 10.1021/jm00041a027 10.7270/Q21G0K9T 8057293 Niwas, S; Chand, P; Pathak, VP; Montgomery, JA Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039550 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039550&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 44461313 103946747 CHEMBL79666 ZINC26499679 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50036355 Nc1nc2c(Cc3ccsc3)c[nH]c2c(=O)[nH]1 InChI=1S/C11H10N4OS/c12-11-14-8-7(3-6-1-2-17-5-6)4-13-9(8)10(16)15-11/h1-2,4-5,13H,3H2,(H3,12,14,15,16) QDPMHXUWMPNTEQ-UHFFFAOYSA-N 50039544 2-Amino-7-thiophen-3-ylmethyl-3,5-dihydro-pyrrolo[3,2-d]pyrimidin-4-one::CHEMBL79784 Purine nucleoside phosphorylase Rattus norvegicus 25 ChEMBL 10.1021/jm00041a027 10.7270/Q21G0K9T 8057293 Niwas, S; Chand, P; Pathak, VP; Montgomery, JA Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039544 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039544&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 3035609 103946742 CHEMBL79784 ZINC00005543 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50036356 CC(C)(CCn1cnc2c1nc[nH]c2=O)CCP(O)(O)=O InChI=1S/C12H19N4O4P/c1-12(2,4-6-21(18,19)20)3-5-16-8-15-9-10(16)13-7-14-11(9)17/h7-8H,3-6H2,1-2H3,(H,13,14,17)(H2,18,19,20) KIMPUJXERPVMFK-UHFFFAOYSA-N 50039552 CHEMBL267312::[3,3-Dimethyl-5-(6-oxo-1,6-dihydro-purin-9-yl)-pentyl]-phosphonic acid Purine nucleoside phosphorylase Rattus norvegicus 210 ChEMBL 10.1021/jm00041a027 10.7270/Q21G0K9T 8057293 Niwas, S; Chand, P; Pathak, VP; Montgomery, JA Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039552 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039552&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 44268617 103946749 CHEMBL267312 ZINC13735748 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50036357 Nc1nc2c(nc(N)[nH]c2=O)n1Cc1ccccc1 InChI=1S/C12H12N6O/c13-11-16-9-8(10(19)17-11)15-12(14)18(9)6-7-4-2-1-3-5-7/h1-5H,6H2,(H2,14,15)(H3,13,16,17,19) DPDYTYOWSIRPMB-UHFFFAOYSA-N 50005799 2,8-Diamino-9-benzyl-1,9-dihydro-purin-6-one::CHEMBL8230 Purine nucleoside phosphorylase Rattus norvegicus 200 ChEMBL 10.1021/jm00041a027 10.7270/Q21G0K9T 8057293 Niwas, S; Chand, P; Pathak, VP; Montgomery, JA Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005799&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 127668 103919224 CHEMBL8230 ZINC16958226 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50036358 Nc1nc2n(CCCCCP(O)(O)=O)cnc2c(=O)[nH]1 InChI=1S/C10H16N5O4P/c11-10-13-8-7(9(16)14-10)12-6-15(8)4-2-1-3-5-20(17,18)19/h6H,1-5H2,(H2,17,18,19)(H3,11,13,14,16) ZQMIYPAADORARG-UHFFFAOYSA-N 50039559 CHEMBL267803::[5-(2-Amino-6-oxo-1,6-dihydro-purin-9-yl)-pentyl]-phosphonic acid Purine nucleoside phosphorylase Rattus norvegicus 170 ChEMBL 10.1021/jm00041a027 10.7270/Q21G0K9T 8057293 Niwas, S; Chand, P; Pathak, VP; Montgomery, JA Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039559 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039559&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 10017722 103946756 CHEMBL267803 ZINC13735754 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50036359 Nc1nc2nc[nH]c2c(=O)[nH]1 InChI=1S/C5H5N5O/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11) UYTPUPDQBNUYGX-UHFFFAOYSA-N 50200094 2-amino-1,9-dihydro-6H-purin-6-one::CHEMBL219568::Gua::guanine Purine nucleoside phosphorylase Rattus norvegicus 5000 ChEMBL 10.1021/jm00041a027 10.7270/Q21G0K9T 8057293 Niwas, S; Chand, P; Pathak, VP; Montgomery, JA Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50200094 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50200094&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 764 104080533 30755 CHEMBL219568 4556 ZINC00895129 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50036360 Nc1nc2c(Cc3ccccc3)c[nH]c2c(=O)[nH]1 InChI=1S/C13H12N4O/c14-13-16-10-9(6-8-4-2-1-3-5-8)7-15-11(10)12(18)17-13/h1-5,7,15H,6H2,(H3,14,16,17,18) ZBEJFMQAPZKPCM-UHFFFAOYSA-N 50039547 2-Amino-7-benzyl-3,5-dihydro-pyrrolo[3,2-d]pyrimidin-4-one::2-amino-7-benzyl-3H-pyrrolo[3,2-d]pyrimidin-4(5H)-one::CHEMBL310202 Purine nucleoside phosphorylase Rattus norvegicus 51 ChEMBL 10.1021/jm00041a027 10.7270/Q21G0K9T 8057293 Niwas, S; Chand, P; Pathak, VP; Montgomery, JA Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039547 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039547&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 9881238 103946744 CHEMBL310202 ZINC00005887 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50036361 O=c1[nH]cnc2nc[nH]c12 InChI=1S/C5H2N4O/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H UYLWKSJTHLRFBX-UHFFFAOYSA-N 82018 CAS_790::CHEMBL1427::Hypoxanthine::NSC_790 Purine nucleoside phosphorylase Rattus norvegicus 17000 ChEMBL 10.1021/jm00041a027 10.7270/Q21G0K9T 8057293 Niwas, S; Chand, P; Pathak, VP; Montgomery, JA Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82018&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search HPA 2W55,2EES,2EET,2EEU,2EEV,2EEW,1ZAY,1PNR,4NYD,1BDI,1BDH,5MX4,1JFS,1JFT,6HGQ,1VPW,6II7,3ENZ,1VFN,4FEL,4FEN,4FEJ,4FE5,3OZF,3OZB,2PUD,2PUG,1A9Q,1A9T,3SCZ,3LBA,3PAN,4DAB,5MX6,3NRZ,2W3R,5C7W,5C7U,1QQA,1QQB,5IFK,1JH9,1QPZ,1QP7,1QP4,1QP0,3FNQ,1A9R,5TBU,5MX8,4UC0 790 131342592 17368 CHEMBL1427 4555 ZINC18153302 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50036362 O=c1[nH]cnc2c(Cc3cccnc3)c[nH]c12 InChI=1S/C12H10N4O/c17-12-11-10(15-7-16-12)9(6-14-11)4-8-2-1-3-13-5-8/h1-3,5-7,14H,4H2,(H,15,16,17) HFPSHRVJTXLPIA-UHFFFAOYSA-N 50039546 7-Pyridin-3-ylmethyl-3,5-dihydro-pyrrolo[3,2-d]pyrimidin-4-one::CHEMBL83053 Purine nucleoside phosphorylase Rattus norvegicus 40 ChEMBL 10.1021/jm00041a027 10.7270/Q21G0K9T 8057293 Niwas, S; Chand, P; Pathak, VP; Montgomery, JA Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039546 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039546&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 10376401 103946743 CHEMBL83053 ZINC00019373 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50038693 CC(C)(CCS)CCn1cnc2c1nc(N)[nH]c2=S InChI=1S/C12H19N5S2/c1-12(2,4-6-18)3-5-17-7-14-8-9(17)15-11(13)16-10(8)19/h7,18H,3-6H2,1-2H3,(H3,13,15,16,19) JNBAIHIYEHDFMN-UHFFFAOYSA-N 50041096 2-Amino-9-(5-mercapto-3,3-dimethyl-pentyl)-1,9-dihydro-purine-6-thione::CHEMBL268288 Purine nucleoside phosphorylase Rattus norvegicus 95000 ChEMBL 10.1021/jm00034a008 10.7270/Q2348JFD 8164252 Guida, WC; Elliott, RD; Thomas, HJ; Secrist, JA; Babu, YS; Bugg, CE; Erion, MD; Ealick, SE; Montgomery, JA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041096&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 10424727 103972940 CHEMBL268288 ZINC13735775 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50038706 CC(C)(CCn1cnc2c1nc(N)[nH]c2=O)CCS(O)(=O)=O InChI=1S/C12H19N5O4S/c1-12(2,4-6-22(19,20)21)3-5-17-7-14-8-9(17)15-11(13)16-10(8)18/h7H,3-6H2,1-2H3,(H,19,20,21)(H3,13,15,16,18) FHNIPDPZHMAHGR-UHFFFAOYSA-N 50041095 5-(2-Amino-6-oxo-1,6-dihydro-purin-9-yl)-3,3-dimethyl-pentane-1-sulfonic acid::CHEMBL13415 Purine nucleoside phosphorylase Rattus norvegicus 180 ChEMBL 10.1021/jm00034a008 10.7270/Q2348JFD 8164252 Guida, WC; Elliott, RD; Thomas, HJ; Secrist, JA; Babu, YS; Bugg, CE; Erion, MD; Ealick, SE; Montgomery, JA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041095 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041095&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 10336678 103972939 CHEMBL13415 C15521 ZINC13735760 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50038710 CC(C)(CCC#N)CCn1cnc2c1nc(N)[nH]c2=O InChI=1S/C13H18N6O/c1-13(2,4-3-6-14)5-7-19-8-16-9-10(19)17-12(15)18-11(9)20/h8H,3-5,7H2,1-2H3,(H3,15,17,18,20) AWDFTSRKFYMKCG-UHFFFAOYSA-N 50041094 6-(2-Amino-6-oxo-1,6-dihydro-purin-9-yl)-4,4-dimethyl-hexanenitrile::CHEMBL13115 Purine nucleoside phosphorylase Rattus norvegicus >300000 ChEMBL 10.1021/jm00034a008 10.7270/Q2348JFD 8164252 Guida, WC; Elliott, RD; Thomas, HJ; Secrist, JA; Babu, YS; Bugg, CE; Erion, MD; Ealick, SE; Montgomery, JA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041094 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041094&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 10265360 103972938 CHEMBL13115 ZINC13735772 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50038712 CC(C)(CCC(O)=O)CCn1cnc2c1nc(N)[nH]c2=O InChI=1S/C13H19N5O3/c1-13(2,4-3-8(19)20)5-6-18-7-15-9-10(18)16-12(14)17-11(9)21/h7H,3-6H2,1-2H3,(H,19,20)(H3,14,16,17,21) JQCMGWXHGBXXRX-UHFFFAOYSA-N 50041097 6-(2-Amino-6-oxo-1,6-dihydro-purin-9-yl)-4,4-dimethyl-hexanoic acid::CHEMBL13195 Purine nucleoside phosphorylase Rattus norvegicus 290000 ChEMBL 10.1021/jm00034a008 10.7270/Q2348JFD 8164252 Guida, WC; Elliott, RD; Thomas, HJ; Secrist, JA; Babu, YS; Bugg, CE; Erion, MD; Ealick, SE; Montgomery, JA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041097&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 10040040 103972941 CHEMBL13195 ZINC13735766 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50038713 CC(C)(CCC(N)=O)CCn1cnc2c1nc(N)[nH]c2=O InChI=1S/C13H20N6O2/c1-13(2,4-3-8(14)20)5-6-19-7-16-9-10(19)17-12(15)18-11(9)21/h7H,3-6H2,1-2H3,(H2,14,20)(H3,15,17,18,21) KESWIHGGNHKQFL-UHFFFAOYSA-N 50041098 6-(2-Amino-6-oxo-1,6-dihydro-purin-9-yl)-4,4-dimethyl-hexanoic acid amide::CHEMBL268940 Purine nucleoside phosphorylase Rattus norvegicus >300000 ChEMBL 10.1021/jm00034a008 10.7270/Q2348JFD 8164252 Guida, WC; Elliott, RD; Thomas, HJ; Secrist, JA; Babu, YS; Bugg, CE; Erion, MD; Ealick, SE; Montgomery, JA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041098 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041098&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 10266338 103972942 CHEMBL268940 ZINC13735769 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50038714 CC(C)(CCn1cnc2c1nc(N)[nH]c2=O)CCP(O)(O)=O InChI=1S/C12H20N5O4P/c1-12(2,4-6-22(19,20)21)3-5-17-7-14-8-9(17)15-11(13)16-10(8)18/h7H,3-6H2,1-2H3,(H2,19,20,21)(H3,13,15,16,18) UYGTVQNSPBEEPR-UHFFFAOYSA-N 50039551 CHEMBL13448::[5-(2-Amino-6-oxo-1,6-dihydro-purin-9-yl)-3,3-dimethyl-pentyl]-phosphonic acid Purine nucleoside phosphorylase Rattus norvegicus 2000 ChEMBL 10.1021/jm00034a008 10.7270/Q2348JFD 8164252 Guida, WC; Elliott, RD; Thomas, HJ; Secrist, JA; Babu, YS; Bugg, CE; Erion, MD; Ealick, SE; Montgomery, JA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039551&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 192696 103946748 CHEMBL13448 ZINC31538469 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50038715 CC(C)(CCn1cnc2c1nc(N)[nH]c2=O)CCS(N)(=O)=O InChI=1S/C12H20N6O3S/c1-12(2,4-6-22(14,20)21)3-5-18-7-15-8-9(18)16-11(13)17-10(8)19/h7H,3-6H2,1-2H3,(H2,14,20,21)(H3,13,16,17,19) OFKKAIVCUDNIFM-UHFFFAOYSA-N 50041093 5-(2-Amino-6-oxo-1,6-dihydro-purin-9-yl)-3,3-dimethyl-pentane-1-sulfonic acid amide::CHEMBL443212 Purine nucleoside phosphorylase Rattus norvegicus 100000 ChEMBL 10.1021/jm00034a008 10.7270/Q2348JFD 8164252 Guida, WC; Elliott, RD; Thomas, HJ; Secrist, JA; Babu, YS; Bugg, CE; Erion, MD; Ealick, SE; Montgomery, JA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041093&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 9996602 103972937 CHEMBL443212 ZINC13735763 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50065444 CC(C)(CCn1cnc2c1nc(N)[nH]c2=O)CCS(N)(=O)=O InChI=1S/C12H20N6O3S/c1-12(2,4-6-22(14,20)21)3-5-18-7-15-8-9(18)16-11(13)17-10(8)19/h7H,3-6H2,1-2H3,(H2,14,20,21)(H3,13,16,17,19) OFKKAIVCUDNIFM-UHFFFAOYSA-N 50041093 5-(2-Amino-6-oxo-1,6-dihydro-purin-9-yl)-3,3-dimethyl-pentane-1-sulfonic acid amide::CHEMBL443212 Purine nucleoside phosphorylase Rattus norvegicus >300000 ChEMBL 10.1021/jm00034a008 10.7270/Q2348JFD 8164252 Guida, WC; Elliott, RD; Thomas, HJ; Secrist, JA; Babu, YS; Bugg, CE; Erion, MD; Ealick, SE; Montgomery, JA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041093&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 9996602 103972937 CHEMBL443212 ZINC13735763 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50065445 CC(C)(CCC#N)CCn1cnc2c1nc(N)[nH]c2=O InChI=1S/C13H18N6O/c1-13(2,4-3-6-14)5-7-19-8-16-9-10(19)17-12(15)18-11(9)20/h8H,3-5,7H2,1-2H3,(H3,15,17,18,20) AWDFTSRKFYMKCG-UHFFFAOYSA-N 50041094 6-(2-Amino-6-oxo-1,6-dihydro-purin-9-yl)-4,4-dimethyl-hexanenitrile::CHEMBL13115 Purine nucleoside phosphorylase Rattus norvegicus 260000 ChEMBL 10.1021/jm00034a008 10.7270/Q2348JFD 8164252 Guida, WC; Elliott, RD; Thomas, HJ; Secrist, JA; Babu, YS; Bugg, CE; Erion, MD; Ealick, SE; Montgomery, JA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041094 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041094&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 10265360 103972938 CHEMBL13115 ZINC13735772 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50065448 CC(C)(CCS)CCn1cnc2c1nc(N)[nH]c2=S InChI=1S/C12H19N5S2/c1-12(2,4-6-18)3-5-17-7-14-8-9(17)15-11(13)16-10(8)19/h7,18H,3-6H2,1-2H3,(H3,13,15,16,19) JNBAIHIYEHDFMN-UHFFFAOYSA-N 50041096 2-Amino-9-(5-mercapto-3,3-dimethyl-pentyl)-1,9-dihydro-purine-6-thione::CHEMBL268288 Purine nucleoside phosphorylase Rattus norvegicus 50000 ChEMBL 10.1021/jm00034a008 10.7270/Q2348JFD 8164252 Guida, WC; Elliott, RD; Thomas, HJ; Secrist, JA; Babu, YS; Bugg, CE; Erion, MD; Ealick, SE; Montgomery, JA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041096&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 10424727 103972940 CHEMBL268288 ZINC13735775 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50065450 CC(C)(CCC(O)=O)CCn1cnc2c1nc(N)[nH]c2=O InChI=1S/C13H19N5O3/c1-13(2,4-3-8(19)20)5-6-18-7-15-9-10(18)16-12(14)17-11(9)21/h7H,3-6H2,1-2H3,(H,19,20)(H3,14,16,17,21) JQCMGWXHGBXXRX-UHFFFAOYSA-N 50041097 6-(2-Amino-6-oxo-1,6-dihydro-purin-9-yl)-4,4-dimethyl-hexanoic acid::CHEMBL13195 Purine nucleoside phosphorylase Rattus norvegicus 8000 ChEMBL 10.1021/jm00034a008 10.7270/Q2348JFD 8164252 Guida, WC; Elliott, RD; Thomas, HJ; Secrist, JA; Babu, YS; Bugg, CE; Erion, MD; Ealick, SE; Montgomery, JA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041097&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 10040040 103972941 CHEMBL13195 ZINC13735766 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50065452 CC(C)(CCC(N)=O)CCn1cnc2c1nc(N)[nH]c2=O InChI=1S/C13H20N6O2/c1-13(2,4-3-8(14)20)5-6-19-7-16-9-10(19)17-12(15)18-11(9)21/h7H,3-6H2,1-2H3,(H2,14,20)(H3,15,17,18,21) KESWIHGGNHKQFL-UHFFFAOYSA-N 50041098 6-(2-Amino-6-oxo-1,6-dihydro-purin-9-yl)-4,4-dimethyl-hexanoic acid amide::CHEMBL268940 Purine nucleoside phosphorylase Rattus norvegicus 200000 ChEMBL 10.1021/jm00034a008 10.7270/Q2348JFD 8164252 Guida, WC; Elliott, RD; Thomas, HJ; Secrist, JA; Babu, YS; Bugg, CE; Erion, MD; Ealick, SE; Montgomery, JA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041098 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041098&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 10266338 103972942 CHEMBL268940 ZINC13735769 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50065454 CC(C)(CCn1cnc2c1nc(N)[nH]c2=O)CCS(O)(=O)=O InChI=1S/C12H19N5O4S/c1-12(2,4-6-22(19,20)21)3-5-17-7-14-8-9(17)15-11(13)16-10(8)18/h7H,3-6H2,1-2H3,(H,19,20,21)(H3,13,15,16,18) FHNIPDPZHMAHGR-UHFFFAOYSA-N 50041095 5-(2-Amino-6-oxo-1,6-dihydro-purin-9-yl)-3,3-dimethyl-pentane-1-sulfonic acid::CHEMBL13415 Purine nucleoside phosphorylase Rattus norvegicus 9000 ChEMBL 10.1021/jm00034a008 10.7270/Q2348JFD 8164252 Guida, WC; Elliott, RD; Thomas, HJ; Secrist, JA; Babu, YS; Bugg, CE; Erion, MD; Ealick, SE; Montgomery, JA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041095 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041095&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 10336678 103972939 CHEMBL13415 C15521 ZINC13735760 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5 50065457 CC(C)(CCn1cnc2c1nc(N)[nH]c2=O)CCP(O)(O)=O InChI=1S/C12H20N5O4P/c1-12(2,4-6-22(19,20)21)3-5-17-7-14-8-9(17)15-11(13)16-10(8)18/h7H,3-6H2,1-2H3,(H2,19,20,21)(H3,13,15,16,18) UYGTVQNSPBEEPR-UHFFFAOYSA-N 50039551 CHEMBL13448::[5-(2-Amino-6-oxo-1,6-dihydro-purin-9-yl)-3,3-dimethyl-pentyl]-phosphonic acid Purine nucleoside phosphorylase Rattus norvegicus 44 ChEMBL 10.1021/jm00034a008 10.7270/Q2348JFD 8164252 Guida, WC; Elliott, RD; Thomas, HJ; Secrist, JA; Babu, YS; Bugg, CE; Erion, MD; Ealick, SE; Montgomery, JA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000576&target=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039551&enzyme=Purine+nucleoside+phosphorylase&column=ki&startPg=0&Increment=50&submit=Search 192696 103946748 CHEMBL13448 ZINC31538469 1 MENEFTYEDYQRTAEWLRSHTKHRPQVAVICGSGLGGLTAKLTQPQAFDYNEIPNFPQSTVQGHAGRLVFGFLNGRSCVMMQGRFHMYEGYSLSKVTFPVRVFHLLGVDTLVVTNAAGGLNPKFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFNAWKQMGEQRELQEGTYIMSAGPTFETVAESCLLRMLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVVMDYNNLEKASHQEVLEAGKAAAQKLEQFVSILMESIPPRERAN Purine nucleoside phosphorylase PNPH_RAT P85973 A6KEC5