BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 120728 Clc1ccccc1C(=O)Nc1c(C#N)c2nc3ccccc3nc2n1CC=C InChI=1S/C21H14ClN5O/c1-2-11-27-19(26-21(28)13-7-3-4-8-15(13)22)14(12-23)18-20(27)25-17-10-6-5-9-16(17)24-18/h2-10H,1,11H2,(H,26,28) SZRJZDDPKYJEDA-UHFFFAOYSA-N 32030 2-chloranyl-N-(3-cyano-1-prop-2-enyl-pyrrolo[3,2-b]quinoxalin-2-yl)benzamide::2-chloro-N-(3-cyano-1-prop-2-enyl-2-pyrrolo[3,2-b]quinoxalinyl)benzamide::2-chloro-N-(3-cyano-1-prop-2-enylpyrrolo[3,2-b]quinoxalin-2-yl)benzamide::MLS000079922::N-(1-allyl-3-cyano-pyrrolo[3,2-b]quinoxalin-2-yl)-2-chloro-benzamide::SMR000039798::cid_658849 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 43617 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32030&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 658849 252615487 ZINC02280965 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120729 CCCCn1c(NC(=O)c2ccco2)c(C(=O)OCC)c2nc3ccccc3nc12 InChI=1S/C22H22N4O4/c1-3-5-12-26-19(25-21(27)16-11-8-13-30-16)17(22(28)29-4-2)18-20(26)24-15-10-7-6-9-14(15)23-18/h6-11,13H,3-5,12H2,1-2H3,(H,25,27) UAQNRDOGNLUULA-UHFFFAOYSA-N 32033 1-butyl-2-(2-furoylamino)pyrrolo[3,2-b]quinoxaline-3-carboxylic acid ethyl ester::1-butyl-2-[[2-furanyl(oxo)methyl]amino]-3-pyrrolo[3,2-b]quinoxalinecarboxylic acid ethyl ester::MLS000079916::SMR000040037::cid_659124::ethyl 1-butyl-2-(furan-2-carbonylamino)pyrrolo[3,2-b]quinoxaline-3-carboxylate::ethyl 1-butyl-2-(furan-2-ylcarbonylamino)pyrrolo[3,2-b]quinoxaline-3-carboxylate Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 62464 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32033&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 659124 252615490 ZINC02290053 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120730 OC1(NC(=O)c2ccccc2)C(=O)c2ccccc2C1=O InChI=1S/C16H11NO4/c18-13-11-8-4-5-9-12(11)14(19)16(13,21)17-15(20)10-6-2-1-3-7-10/h1-9,21H,(H,17,20) FICSYWUBABJDHB-UHFFFAOYSA-N 32085 MLS000085603::N-(2-hydroxy-1,3-diketo-indan-2-yl)benzamide::N-(2-hydroxy-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)benzamide::N-(2-hydroxy-1,3-dioxo-2-indenyl)benzamide::N-(2-hydroxy-1,3-dioxoinden-2-yl)benzamide::N-[2-oxidanyl-1,3-bis(oxidanylidene)inden-2-yl]benzamide::SMR000020538::cid_3237318 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 48978 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32085 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32085&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 3237318 252615537 ZINC03647975 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120731 Cc1nnc(NC(=O)C2C3OC(C=C3)C2C(O)=O)s1 InChI=1S/C11H11N3O4S/c1-4-13-14-11(19-4)12-9(15)7-5-2-3-6(18-5)8(7)10(16)17/h2-3,5-8H,1H3,(H,16,17)(H,12,14,15) NQNCLYCHYSUUSL-UHFFFAOYSA-N 64774 2-[(5-methyl-1,3,4-thiadiazol-2-yl)carbamoyl]-7-oxabicyclo[2.2.1]hept-5-ene-3-carboxylic acid::2-[[(5-methyl-1,3,4-thiadiazol-2-yl)amino]-oxomethyl]-7-oxabicyclo[2.2.1]hept-5-ene-3-carboxylic acid::3-{[(5-methyl-1,3,4-thiadiazol-2-yl)amino]carbonyl}-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid::MLS000085389::SMR000020125::cid_3241653 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64774&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 3241653 252643732 ZINC03906533 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120732 OC12OC3=C(C(=O)CCC3)C1(O)C(=O)c1ccccc21 InChI=1S/C15H12O5/c16-10-6-3-7-11-12(10)14(18)13(17)8-4-1-2-5-9(8)15(14,19)20-11/h1-2,4-5,18-19H,3,6-7H2 RQRSZYHVVUHFRF-UHFFFAOYSA-N 39886 4b,9b-bis(oxidanyl)-7,8-dihydro-6H-indeno[1,2-b][1]benzofuran-9,10-dione::4b,9b-dihydroxy-7,8-dihydro-6H-indeno[1,2-b][1]benzofuran-9,10-dione::4b,9b-dihydroxy-7,8-dihydro-6H-indeno[1,2-b]benzofuran-9,10-dione::4b,9b-dihydroxy-7,8-dihydro-6H-indeno[1,2-b]benzofuran-9,10-quinone::MLS000104338::SMR000054273::cid_2834991 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=39886 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=39886&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 2834991 252620720 ZINC00230059 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120733 CCOC(=O)c1nn(-c2ccc(C)cc2)c(=O)c2c(N)scc12 InChI=1S/C16H15N3O3S/c1-3-22-16(21)13-11-8-23-14(17)12(11)15(20)19(18-13)10-6-4-9(2)5-7-10/h4-8H,3,17H2,1-2H3 NLXRCLZMANQSNK-UHFFFAOYSA-N 64775 5-Amino-4-oxo-3-p-tolyl-3,4-dihydro-thieno[3,4-d]pyridazine-1-carboxylic acid ethyl ester::5-amino-3-(4-methylphenyl)-4-oxo-1-thieno[3,4-d]pyridazinecarboxylic acid ethyl ester::5-amino-4-keto-3-(p-tolyl)thieno[3,4-d]pyridazine-1-carboxylic acid ethyl ester::MLS000528230::SMR000120805::cid_3153302::ethyl 5-amino-3-(4-methylphenyl)-4-oxothieno[3,4-d]pyridazine-1-carboxylate::ethyl 5-azanyl-3-(4-methylphenyl)-4-oxidanylidene-thieno[3,4-d]pyridazine-1-carboxylate Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64775&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 3153302 252643733 ZINC04352490 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120734 O=C1C(Nc2ccccc2)=C(N2CCCCC2)C(=O)c2ccccc12 InChI=1S/C21H20N2O2/c24-20-16-11-5-6-12-17(16)21(25)19(23-13-7-2-8-14-23)18(20)22-15-9-3-1-4-10-15/h1,3-6,9-12,22H,2,7-8,13-14H2 ZTVZJPLQFQZWPX-UHFFFAOYSA-N 42195 2-Phenylamino-3-piperidin-1-yl-[1,4]naphthoquinone::2-anilino-3-(1-piperidinyl)naphthalene-1,4-dione::2-anilino-3-piperidin-1-ylnaphthalene-1,4-dione::2-anilino-3-piperidino-1,4-naphthoquinone::2-phenylazanyl-3-piperidin-1-yl-naphthalene-1,4-dione::MLS000528379::SMR000120954::cid_3147878 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=42195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=42195&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 3147878 252622902 ZINC03904083 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120735 CC(C)CNC(=O)c1c(N)n(Cc2ccc3OCOc3c2)c2nc3ccccc3nc12 InChI=1S/C23H23N5O3/c1-13(2)10-25-23(29)19-20-22(27-16-6-4-3-5-15(16)26-20)28(21(19)24)11-14-7-8-17-18(9-14)31-12-30-17/h3-9,13H,10-12,24H2,1-2H3,(H,25,29) NGMDGQSGCZAQOL-UHFFFAOYSA-N 41677 2-Amino-1-benzo[1,3]dioxol-5-ylmethyl-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylic acid isobutyl-amide::2-amino-1-(1,3-benzodioxol-5-ylmethyl)-N-(2-methylpropyl)-3-pyrrolo[3,2-b]quinoxalinecarboxamide::2-amino-1-(1,3-benzodioxol-5-ylmethyl)-N-(2-methylpropyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide::2-amino-N-isobutyl-1-piperonyl-pyrrolo[3,2-b]quinoxaline-3-carboxamide::2-azanyl-1-(1,3-benzodioxol-5-ylmethyl)-N-(2-methylpropyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide::MLS000556577::SMR000147894::cid_3800606 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41677 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41677&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 3800606 252622398 ZINC05066950 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120736 COCCNC(=O)c1c(N)n(CCC(C)C)c2nc3ccccc3nc12 InChI=1S/C19H25N5O2/c1-12(2)8-10-24-17(20)15(19(25)21-9-11-26-3)16-18(24)23-14-7-5-4-6-13(14)22-16/h4-7,12H,8-11,20H2,1-3H3,(H,21,25) SXUNJBHDIOMXFY-UHFFFAOYSA-N 64776 2-Amino-1-(3-methyl-butyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxylic acid (2-methoxy-ethyl)-amide::2-amino-1-isoamyl-N-(2-methoxyethyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide::2-amino-N-(2-methoxyethyl)-1-(3-methylbutyl)-3-pyrrolo[3,2-b]quinoxalinecarboxamide::2-amino-N-(2-methoxyethyl)-1-(3-methylbutyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide::2-azanyl-N-(2-methoxyethyl)-1-(3-methylbutyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide::MLS000559054::SMR000149370::cid_2031291 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 56486 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64776 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64776&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 2031291 252643734 ZINC02435029 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120737 CCCCN(CC)c1nc(N)c2c(N)nc(OCC)cc2c1C#N InChI=1S/C17H24N6O/c1-4-7-8-23(5-2)17-12(10-18)11-9-13(24-6-3)21-15(19)14(11)16(20)22-17/h9H,4-8H2,1-3H3,(H2,19,21)(H2,20,22) PYLKIUBYVAMNEF-UHFFFAOYSA-N 64777 1,8-bis(azanyl)-3-[butyl(ethyl)amino]-6-ethoxy-2,7-naphthyridine-4-carbonitrile::1,8-diamino-3-[butyl(ethyl)amino]-6-ethoxy-2,7-naphthyridine-4-carbonitrile::MLS000564759::SMR000151991::cid_5216640 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64777&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 5216640 252643735 ZINC25386666 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120738 CCCN(CC1CC1)c1nc(N)c2c(N)nc(OC)cc2c1C#N InChI=1S/C17H22N6O/c1-3-6-23(9-10-4-5-10)17-12(8-18)11-7-13(24-2)21-15(19)14(11)16(20)22-17/h7,10H,3-6,9H2,1-2H3,(H2,19,21)(H2,20,22) QTJLJMNEZPZJLU-UHFFFAOYSA-N 64778 1,8-bis(azanyl)-3-[cyclopropylmethyl(propyl)amino]-6-methoxy-2,7-naphthyridine-4-carbonitrile::1,8-diamino-3-[cyclopropylmethyl(propyl)amino]-6-methoxy-2,7-naphthyridine-4-carbonitrile::MLS000567785::SMR000154351::cid_4875518 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64778 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64778&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 4875518 252643736 ZINC25720008 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120739 Cc1ccc(Cl)cc1NC1=CC(=NS(=O)(=O)c2cccs2)c2ccccc2C1=O InChI=1S/C21H15ClN2O3S2/c1-13-8-9-14(22)11-17(13)23-19-12-18(15-5-2-3-6-16(15)21(19)25)24-29(26,27)20-7-4-10-28-20/h2-12,23H,1H3 BGOWMRGDUSUEFJ-UHFFFAOYSA-N 41036 (NE)-N-[3-(5-chloro-2-methyl-anilino)-4-keto-1-naphthylidene]thiophene-2-sulfonamide::(NE)-N-[3-(5-chloro-2-methylanilino)-4-oxo-1-naphthalenylidene]-2-thiophenesulfonamide::(NE)-N-[3-(5-chloro-2-methylanilino)-4-oxonaphthalen-1-ylidene]thiophene-2-sulfonamide::(NE)-N-[3-[(5-chloranyl-2-methyl-phenyl)amino]-4-oxidanylidene-naphthalen-1-ylidene]thiophene-2-sulfonamide::MLS000535841::SMR000151319::cid_11834461 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 38913 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41036 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41036&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 11834461 252621813 ZINC17823489 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120740 Cc1ccccc1NC1=CC(=NS(=O)(=O)c2cccs2)c2ccccc2C1=O InChI=1S/C21H16N2O3S2/c1-14-7-2-5-10-17(14)22-19-13-18(15-8-3-4-9-16(15)21(19)24)23-28(25,26)20-11-6-12-27-20/h2-13,22H,1H3 DBVTXTMIOWGNNH-UHFFFAOYSA-N 41038 (NE)-N-[3-(2-methylanilino)-4-oxo-1-naphthalenylidene]-2-thiophenesulfonamide::(NE)-N-[3-(2-methylanilino)-4-oxonaphthalen-1-ylidene]thiophene-2-sulfonamide::(NE)-N-[3-[(2-methylphenyl)amino]-4-oxidanylidene-naphthalen-1-ylidene]thiophene-2-sulfonamide::(NE)-N-[4-keto-3-(o-toluidino)-1-naphthylidene]thiophene-2-sulfonamide::MLS000536576::SMR000151472::cid_11834470 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 22349 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41038 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41038&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 11834470 252621815 ZINC18066878 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120741 [O-][N+](=O)c1ccc(=O)[c-](c1)-c1[nH]nn[nH+]1 InChI=1S/C7H4N5O3/c13-6-2-1-4(12(14)15)3-5(6)7-8-10-11-9-7/h1-3H,(H,8,9,10,11)/q-1/p+1 TWWNEEGKMNSDBE-UHFFFAOYSA-O 64779 (6Z)-6-(1,2-dihydro-1,2,3,4-tetrazol-5-ylidene)-4-nitro-cyclohexa-2,4-dien-1-one::(6Z)-6-(1,2-dihydrotetrazol-5-ylidene)-4-nitro-1-cyclohexa-2,4-dienone::(6Z)-6-(1,2-dihydrotetrazol-5-ylidene)-4-nitro-cyclohexa-2,4-dien-1-one::(6Z)-6-(1,2-dihydrotetrazol-5-ylidene)-4-nitrocyclohexa-2,4-dien-1-one::4-nitro-2-(2H-tetraazol-5-yl)phenol::MLS000540078::SMR000162423::cid_11839800 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64779 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64779&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 11839800 252643737 ZINC17154752 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120742 Cc1ccc(cc1)C(=O)NNc1cc(nc(n1)N1CCCC1)N1CCCC1 InChI=1S/C20H26N6O/c1-15-6-8-16(9-7-15)19(27)24-23-17-14-18(25-10-2-3-11-25)22-20(21-17)26-12-4-5-13-26/h6-9,14H,2-5,10-13H2,1H3,(H,24,27)(H,21,22,23) AVHYTXJNAXLTFO-UHFFFAOYSA-N 64780 4-Methyl-benzoic acid N'-(2,6-di-pyrrolidin-1-yl-pyrimidin-4-yl)-hydrazide::MLS000551080::N'-(2,6-dipyrrolidin-1-ylpyrimidin-4-yl)-4-methyl-benzohydrazide::N'-(2,6-dipyrrolidin-1-ylpyrimidin-4-yl)-4-methylbenzohydrazide::N'-(2,6-dipyrrolidinopyrimidin-4-yl)-4-methyl-benzohydrazide::N'-[2,6-bis(1-pyrrolidinyl)-4-pyrimidinyl]-4-methylbenzohydrazide::SMR000176238::cid_1109408 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 64048 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64780 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64780&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 1109408 252643738 ZINC00842943 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120743 Nc1cc2nsnc2cc1Br InChI=1S/C6H4BrN3S/c7-3-1-5-6(2-4(3)8)10-11-9-5/h1-2H,8H2 CDEJXRZSAIZTRF-UHFFFAOYSA-N 40726 (6-bromopiazthiol-5-yl)amine::5-bromanyl-2,1,3-benzothiadiazol-6-amine::5-bromo-2,1,3-benzothiadiazol-6-amine::6-Bromo-benzo[1,2,5]thiadiazol-5-ylamine::MLS000556153::SMR000174162::cid_3096032 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=40726 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=40726&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 3096032 252621543 ZINC02566853 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120744 Cc1ccc(NC2=C(N3CCOCC3)C(=O)c3ccccc3C2=O)cc1 InChI=1S/C21H20N2O3/c1-14-6-8-15(9-7-14)22-18-19(23-10-12-26-13-11-23)21(25)17-5-3-2-4-16(17)20(18)24/h2-9,22H,10-13H2,1H3 UBKOWVOSSLUPDI-UHFFFAOYSA-N 42219 2-(4-methylanilino)-3-(4-morpholinyl)naphthalene-1,4-dione::2-(4-methylanilino)-3-morpholin-4-ylnaphthalene-1,4-dione::2-Morpholin-4-yl-3-p-tolylamino-[1,4]naphthoquinone::2-[(4-methylphenyl)amino]-3-morpholin-4-yl-naphthalene-1,4-dione::2-morpholino-3-(p-toluidino)-1,4-naphthoquinone::MLS000557780::SMR000178047::cid_2893413 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=42219 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=42219&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 2893413 252622924 ZINC04063181 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120745 Oc1ccc(C=CC(=O)c2ccc(NC3=C(N4CCCCC4)C(=O)c4ccccc4C3=O)cc2)cc1 InChI=1S/C30H26N2O4/c33-23-15-8-20(9-16-23)10-17-26(34)21-11-13-22(14-12-21)31-27-28(32-18-4-1-5-19-32)30(36)25-7-3-2-6-24(25)29(27)35/h2-3,6-17,31,33H,1,4-5,18-19H2 XJOPTGLQFWIKGR-UHFFFAOYSA-N 42221 2-({4-[3-(4-hydroxyphenyl)acryloyl]phenyl}amino)-3-(1-piperidinyl)naphthoquinone::2-[4-[(E)-3-(4-hydroxyphenyl)-1-oxoprop-2-enyl]anilino]-3-(1-piperidinyl)naphthalene-1,4-dione::2-[4-[(E)-3-(4-hydroxyphenyl)acryloyl]anilino]-3-piperidino-1,4-naphthoquinone::2-[4-[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]anilino]-3-piperidin-1-ylnaphthalene-1,4-dione::2-[[4-[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]phenyl]amino]-3-piperidin-1-yl-naphthalene-1,4-dione::MLS000578787::SMR000186576::cid_5341375 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=42221 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=42221&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 5341375 252622926 ZINC96243300 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120746 CC(=O)c1ccc(NC2=C(N3CCOCC3)C(=O)c3ccccc3C2=O)cc1 InChI=1S/C22H20N2O4/c1-14(25)15-6-8-16(9-7-15)23-19-20(24-10-12-28-13-11-24)22(27)18-5-3-2-4-17(18)21(19)26/h2-9,23H,10-13H2,1H3 QVZQFHHACGJXKD-UHFFFAOYSA-N 42222 2-(4-acetylanilino)-3-(4-morpholinyl)naphthalene-1,4-dione::2-(4-acetylanilino)-3-morpholin-4-ylnaphthalene-1,4-dione::2-(4-acetylanilino)-3-morpholino-1,4-naphthoquinone::2-[(4-acetylphenyl)amino]-3-(4-morpholinyl)naphthoquinone::2-[(4-ethanoylphenyl)amino]-3-morpholin-4-yl-naphthalene-1,4-dione::MLS000579716::SMR000186447::cid_2854583 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=42222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=42222&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 2854583 252622927 ZINC04785588 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120747 Oc1ccc(CN=Nc2cc(nc(n2)N2CCCC2)N2CCCC2)cc1 InChI=1S/C19H24N6O/c26-16-7-5-15(6-8-16)14-20-23-17-13-18(24-9-1-2-10-24)22-19(21-17)25-11-3-4-12-25/h5-8,13,26H,1-4,9-12,14H2 KAACMQXCCLGJPW-UHFFFAOYSA-N 64781 4-[[2-(2,6-dipyrrolidin-1-ylpyrimidin-4-yl)hydrazinyl]methylidene]cyclohexa-2,5-dien-1-one::4-[[N'-(2,6-dipyrrolidinopyrimidin-4-yl)hydrazino]methylene]cyclohexa-2,5-dien-1-one::4-[[[2,6-bis(1-pyrrolidinyl)-4-pyrimidinyl]hydrazo]methylidene]-1-cyclohexa-2,5-dienone::4-hydroxybenzaldehyde (2,6-di-1-pyrrolidinyl-4-pyrimidinyl)hydrazone::MLS000578760::SMR000186252::cid_5340670 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64781 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64781&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 91897576 252643739 ZINC13130552 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120748 Oc1ccccc1CN=Nc1cc(nc(n1)N1CCCC1)N1CCCC1 InChI=1S/C19H24N6O/c26-16-8-2-1-7-15(16)14-20-23-17-13-18(24-9-3-4-10-24)22-19(21-17)25-11-5-6-12-25/h1-2,7-8,13,26H,3-6,9-12,14H2 JXFIFHFQPYKXLG-UHFFFAOYSA-N 64782 (6E)-6-[[2-(2,6-dipyrrolidin-1-ylpyrimidin-4-yl)hydrazinyl]methylidene]cyclohexa-2,4-dien-1-one::(6E)-6-[[N'-(2,6-dipyrrolidinopyrimidin-4-yl)hydrazino]methylene]cyclohexa-2,4-dien-1-one::(6E)-6-[[[2,6-bis(1-pyrrolidinyl)-4-pyrimidinyl]hydrazo]methylidene]-1-cyclohexa-2,4-dienone::2-hydroxybenzaldehyde (2,6-di-1-pyrrolidinyl-4-pyrimidinyl)hydrazone::MLS000577672::SMR000186087::cid_6614484 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 34360 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64782&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 91897577 252643740 ZINC04599116 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120749 CCOc1ccc(NC(=S)Nc2ccc3nsnc3c2)cc1 InChI=1S/C15H14N4OS2/c1-2-20-12-6-3-10(4-7-12)16-15(21)17-11-5-8-13-14(9-11)19-22-18-13/h3-9H,2H2,1H3,(H2,16,17,21) BESWLCDPXSVTTF-UHFFFAOYSA-N 64783 1-(2,1,3-benzothiadiazol-5-yl)-3-(4-ethoxyphenyl)thiourea::1-piazthiol-5-yl-3-p-phenetyl-thiourea::MLS000576242::N-2,1,3-benzothiadiazol-5-yl-N'-(4-ethoxyphenyl)thiourea::SMR000197073::cid_804043 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64783 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64783&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 804043 252643741 ZINC08690078 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120750 Oc1ccc(CN=Nc2cc(nc(n2)N2CCOCC2)N2CCOCC2)c(O)c1 InChI=1S/C19H24N6O4/c26-15-2-1-14(16(27)11-15)13-20-23-17-12-18(24-3-7-28-8-4-24)22-19(21-17)25-5-9-29-10-6-25/h1-2,11-12,26-27H,3-10,13H2 AMCMFWIDXWPRTG-UHFFFAOYSA-N 64784 (4E)-4-[[2-(2,6-dimorpholin-4-ylpyrimidin-4-yl)hydrazinyl]methylidene]-3-hydroxycyclohexa-2,5-dien-1-one::(4E)-4-[[2-(2,6-dimorpholin-4-ylpyrimidin-4-yl)hydrazinyl]methylidene]-3-oxidanyl-cyclohexa-2,5-dien-1-one::(4E)-4-[[N'-(2,6-dimorpholinopyrimidin-4-yl)hydrazino]methylene]-3-hydroxy-cyclohexa-2,5-dien-1-one::(4E)-4-[[[2,6-bis(4-morpholinyl)-4-pyrimidinyl]hydrazo]methylidene]-3-hydroxy-1-cyclohexa-2,5-dienone::4-[(2,6-Di-morpholin-4-yl-pyrimidin-4-yl)-hydrazonomethyl]-benzene-1,3-diol::MLS000553546::SMR000171512::cid_6614507 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64784&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 91429170 252643742 ZINC13118855 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120751 Clc1ccc(cc1)C1OC11C(=O)c2ccccc2C1=O InChI=1S/C16H9ClO3/c17-10-7-5-9(6-8-10)15-16(20-15)13(18)11-3-1-2-4-12(11)14(16)19/h1-8,15H TXOAAFVHJAZXAJ-UHFFFAOYSA-N 61173 3'-(4-chlorophenyl)spiro[indane-2,2'-oxirane]-1,3-quinone::3'-(4-chlorophenyl)spiro[indene-2,2'-oxirane]-1,3-dione::MLS000567016::SMR000177648::cid_3142215 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=61173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=61173&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 3142215 252640334 ZINC00349859 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120752 COc1ccc(CN=Nc2cc(nc(n2)N(C)C)N(C)C)cc1 InChI=1S/C16H22N6O/c1-21(2)15-10-14(18-16(19-15)22(3)4)20-17-11-12-6-8-13(23-5)9-7-12/h6-10H,11H2,1-5H3 BBLXPLJXFFEROW-UHFFFAOYSA-N 34768 6-N-[(4-methoxyphenyl)methylideneamino]-2-N,2-N,4-N,4-N-tetramethylpyrimidine-2,4,6-triamine::6-[N'-(4-Methoxy-benzylidene)-hydrazino]-N*2*,N*2*,N*4*,N*4*-tetramethyl-pyrimidine-2,4-diamine::MLS000566872::N6-[(4-methoxyphenyl)methylideneamino]-N2,N2,N4,N4-tetramethyl-pyrimidine-2,4,6-triamine::N6-[(4-methoxyphenyl)methylideneamino]-N2,N2,N4,N4-tetramethylpyrimidine-2,4,6-triamine::SMR000175280::[2-(dimethylamino)-6-(N'-p-anisylidenehydrazino)pyrimidin-4-yl]-dimethyl-amine::cid_2850301 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34768 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34768&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 91896219 252617415 ZINC33395645 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120753 Oc1cccc(CN=Nc2cc(nc(n2)N2CCCC2)N2CCCC2)c1 InChI=1S/C19H24N6O/c26-16-7-5-6-15(12-16)14-20-23-17-13-18(24-8-1-2-9-24)22-19(21-17)25-10-3-4-11-25/h5-7,12-13,26H,1-4,8-11,14H2 HYWJTLYOGDKCED-UHFFFAOYSA-N 64785 3-[(2,6-Di-pyrrolidin-1-yl-pyrimidin-4-yl)-hydrazonomethyl]-phenol::3-[[(2,6-dipyrrolidin-1-ylpyrimidin-4-yl)hydrazinylidene]methyl]phenol::3-[[(2,6-dipyrrolidinopyrimidin-4-yl)hydrazono]methyl]phenol::3-[[[2,6-bis(1-pyrrolidinyl)-4-pyrimidinyl]hydrazinylidene]methyl]phenol::MLS000553694::SMR000171513::cid_2851959 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 21556 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64785&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 91897578 252643743 ZINC33395956 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120754 Cc1cc(C)c(cc1C)S(=O)(=O)N=C1C=C(Sc2nnc[nH]2)C(=O)c2ccccc12 InChI=1S/C21H18N4O3S2/c1-12-8-14(3)19(9-13(12)2)30(27,28)25-17-10-18(29-21-22-11-23-24-21)20(26)16-7-5-4-6-15(16)17/h4-11H,1-3H3,(H,22,23,24) VQVNQUVGIDYCOK-UHFFFAOYSA-N 50253 (NZ)-N-[4-keto-3-(1H-1,2,4-triazol-5-ylthio)-1-naphthylidene]-2,4,5-trimethyl-benzenesulfonamide::2,4,5-trimethyl-N-[(1Z)-4-oxo-3-(1H-1,2,4-triazol-3-ylthio)naphthalen-1(4H)-ylidene]benzenesulfonamide::2,4,5-trimethyl-N-[4-oxidanylidene-3-(1H-1,2,4-triazol-5-ylsulfanyl)naphthalen-1-ylidene]benzenesulfonamide::2,4,5-trimethyl-N-[4-oxo-3-(1H-1,2,4-triazol-5-ylsulfanyl)naphthalen-1-ylidene]benzenesulfonamide::2,4,5-trimethyl-N-[4-oxo-3-(1H-1,2,4-triazol-5-ylthio)-1-naphthalenylidene]benzenesulfonamide::MLS000585904::N-[4-keto-3-(1H-1,2,4-triazol-5-ylthio)-1-naphthylidene]-2,4,5-trimethyl-benzenesulfonamide::SMR000207685::cid_3318213 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 18550 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 45489546 252630519 ZINC02259160 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120755 COc1ccc(NC(=S)Nc2ccc3nsnc3c2)cc1 InChI=1S/C14H12N4OS2/c1-19-11-5-2-9(3-6-11)15-14(20)16-10-4-7-12-13(8-10)18-21-17-12/h2-8H,1H3,(H2,15,16,20) FXZNHTKAOTUVHO-UHFFFAOYSA-N 64786 1-(2,1,3-benzothiadiazol-5-yl)-3-(4-methoxyphenyl)thiourea::1-(4-methoxyphenyl)-3-piazthiol-5-yl-thiourea::MLS000585342::N-2,1,3-benzothiadiazol-5-yl-N'-(4-methoxyphenyl)thiourea::SMR000204105::cid_753169 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64786&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 753169 252643744 ZINC08683197 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120756 CC(=O)C(C(C)=O)C1(O)C(=O)c2ccccc2C1=O InChI=1S/C14H12O5/c1-7(15)11(8(2)16)14(19)12(17)9-5-3-4-6-10(9)13(14)18/h3-6,11,19H,1-2H3 UNWNYZDNRAAMSU-UHFFFAOYSA-N 64787 2-(1-Acetyl-2-oxo-propyl)-2-hydroxy-indan-1,3-dione::2-(1-acetyl-2-keto-propyl)-2-hydroxy-indane-1,3-quinone::2-(2,4-dioxopentan-3-yl)-2-hydroxyindene-1,3-dione::2-[2,4-bis(oxidanylidene)pentan-3-yl]-2-oxidanyl-indene-1,3-dione::MLS000588745::SMR000212365::cid_766079 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64787&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 766079 252643745 ZINC12436967 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120757 Cc1[nH]n(-c2ccccc2)c(=O)c1C(c1c(C)[nH]n(-c2ccccc2)c1=O)c1ccc(cc1)[N+]([O-])=O InChI=1S/C27H23N5O4/c1-17-23(26(33)30(28-17)20-9-5-3-6-10-20)25(19-13-15-22(16-14-19)32(35)36)24-18(2)29-31(27(24)34)21-11-7-4-8-12-21/h3-16,25,28-29H,1-2H3 KFOMNSILEPOUOI-UHFFFAOYSA-N 64788 4-[(5-keto-3-methyl-1-phenyl-3-pyrazolin-4-yl)-(4-nitrophenyl)methyl]-5-methyl-2-phenyl-3-pyrazolin-3-one::5-methyl-4-[(5-methyl-3-oxidanylidene-2-phenyl-1H-pyrazol-4-yl)-(4-nitrophenyl)methyl]-2-phenyl-1H-pyrazol-3-one::5-methyl-4-[(5-methyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-(4-nitrophenyl)methyl]-2-phenyl-1H-pyrazol-3-one::MLS000592130::SMR000218378::cid_2251550 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 29894 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64788&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 2251550 252643746 ZINC17747492 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120758 [O-][N+](=O)c1ccccc1N1CCN(CC1)C1=C(Cl)C(=O)c2ccccc2C1=O InChI=1S/C20H16ClN3O4/c21-17-18(20(26)14-6-2-1-5-13(14)19(17)25)23-11-9-22(10-12-23)15-7-3-4-8-16(15)24(27)28/h1-8H,9-12H2 SPHZCDKPHYBGQR-UHFFFAOYSA-N 33124 2-Chloro-3-[4-(2-nitro-phenyl)-piperazin-1-yl]-[1,4]naphthoquinone::2-chloranyl-3-[4-(2-nitrophenyl)piperazin-1-yl]naphthalene-1,4-dione::2-chloro-3-[4-(2-nitrophenyl)-1-piperazinyl]naphthalene-1,4-dione::2-chloro-3-[4-(2-nitrophenyl)piperazin-1-yl]naphthalene-1,4-dione::2-chloro-3-[4-(2-nitrophenyl)piperazino]-1,4-naphthoquinone::MLS000588199::SMR000220218::cid_4561725 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=33124 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=33124&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 4561725 252616252 ZINC04703347 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120759 OC(=O)c1[nH]nnc1-c1ccccc1 InChI=1S/C9H7N3O2/c13-9(14)8-7(10-12-11-8)6-4-2-1-3-5-6/h1-5H,(H,13,14)(H,10,11,12) KZVFXYXQNAYXFT-UHFFFAOYSA-N 64789 5-phenyl-2H-1,2,3-triazole-4-carboxylic acid::5-phenyl-2H-triazole-4-carboxylic acid::MLS000716530::SMR000278047::cid_3159718 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64789 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64789&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 3159718 252643747 ZINC04384478 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120760 CN(C)c1cc(N=NCc2ccccc2)nc(n1)N(C)C InChI=1S/C15H20N6/c1-20(2)14-10-13(17-15(18-14)21(3)4)19-16-11-12-8-6-5-7-9-12/h5-10H,11H2,1-4H3 AAUUMJRQTYQEHL-UHFFFAOYSA-N 34893 6-N-(benzylideneamino)-2-N,2-N,4-N,4-N-tetramethylpyrimidine-2,4,6-triamine::MLS000709098::N2,N2,N4,N4-tetramethyl-N6-[(phenylmethylene)amino]pyrimidine-2,4,6-triamine::N2,N2,N4,N4-tetramethyl-N6-[(phenylmethylidene)amino]pyrimidine-2,4,6-triamine::SMR000282965::[4-(N'-benzalhydrazino)-6-(dimethylamino)pyrimidin-2-yl]-dimethyl-amine::[4-[(N''Z)-N''-benzalhydrazino]-6-(dimethylamino)pyrimidin-2-yl]-dimethyl-amine::[4-[(N'Z)-N'-benzalhydrazino]-6-(dimethylamino)pyrimidin-2-yl]-dimethyl-amine::cid_2853497 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34893 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34893&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 91896227 252617538 ZINC32606264 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120761 [O-][N+](=O)c1ccc(cc1)C(=O)NNc1cc(nc(n1)N1CCCC1)N1CCCC1 InChI=1S/C19H23N7O3/c27-18(14-5-7-15(8-6-14)26(28)29)23-22-16-13-17(24-9-1-2-10-24)21-19(20-16)25-11-3-4-12-25/h5-8,13H,1-4,9-12H2,(H,23,27)(H,20,21,22) XMGBAJDKCRZPLQ-UHFFFAOYSA-N 61195 MLS000765857::N'-(2,6-dipyrrolidin-1-ylpyrimidin-4-yl)-4-nitro-benzohydrazide::N'-(2,6-dipyrrolidin-1-ylpyrimidin-4-yl)-4-nitrobenzohydrazide::N'-(2,6-dipyrrolidinopyrimidin-4-yl)-4-nitro-benzohydrazide::N'-[2,6-bis(1-pyrrolidinyl)-4-pyrimidinyl]-4-nitrobenzohydrazide::SMR000278963::cid_3121369 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=61195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=61195&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 3121369 252640356 ZINC00842944 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120762 COc1ccccc1CN=Nc1cc(nc(n1)N(C)C)N(C)C InChI=1S/C16H22N6O/c1-21(2)15-10-14(18-16(19-15)22(3)4)20-17-11-12-8-6-7-9-13(12)23-5/h6-10H,11H2,1-5H3 LOVGAQIEXBOEEJ-UHFFFAOYSA-N 61198 2-methoxybenzaldehyde [2,6-bis(dimethylamino)pyrimidin-4-yl]hydrazone::6-N-[(2-methoxyphenyl)methylideneamino]-2-N,2-N,4-N,4-N-tetramethylpyrimidine-2,4,6-triamine::MLS000720211::N6-[(2-methoxyphenyl)methylideneamino]-N2,N2,N4,N4-tetramethyl-pyrimidine-2,4,6-triamine::N6-[(2-methoxyphenyl)methylideneamino]-N2,N2,N4,N4-tetramethylpyrimidine-2,4,6-triamine::SMR000304740::[2-(dimethylamino)-6-(N'-o-anisylidenehydrazino)pyrimidin-4-yl]-dimethyl-amine::cid_4035805 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=61198 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=61198&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 91897466 252640359 ZINC13139825 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120763 CC(=O)Nc1ccc(NC2=CC(=NS(=O)(=O)c3cccs3)c3ccccc3C2=O)cc1 InChI=1S/C22H17N3O4S2/c1-14(26)23-15-8-10-16(11-9-15)24-20-13-19(17-5-2-3-6-18(17)22(20)27)25-31(28,29)21-7-4-12-30-21/h2-13,24H,1H3,(H,23,26) DQKXIWVDLDLOSL-UHFFFAOYSA-N 47968 MLS000686315::N-[4-({(4Z)-1-oxo-4-[(thien-2-ylsulfonyl)imino]-1,4-dihydronaphthalen-2-yl}amino)phenyl]acetamide::N-[4-[(1-oxidanylidene-4-thiophen-2-ylsulfonylimino-naphthalen-2-yl)amino]phenyl]ethanamide::N-[4-[(1-oxo-4-thiophen-2-ylsulfonylimino-2-naphthalenyl)amino]phenyl]acetamide::N-[4-[(1-oxo-4-thiophen-2-ylsulfonyliminonaphthalen-2-yl)amino]phenyl]acetamide::N-[4-[[(4Z)-1-keto-4-(2-thienylsulfonylimino)-2-naphthyl]amino]phenyl]acetamide::N-[4-[[1-keto-4-(2-thienylsulfonylimino)-2-naphthyl]amino]phenyl]acetamide::SMR000313158::cid_3715121 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=47968 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=47968&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 44786402 252628266 ZINC13143205 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120764 CC(=O)C1=C(C)OC2(O)c3ccccc3C(=O)C12O InChI=1S/C14H12O5/c1-7(15)11-8(2)19-14(18)10-6-4-3-5-9(10)12(16)13(11,14)17/h3-6,17-18H,1-2H3 RSHLNQWVQAWODW-UHFFFAOYSA-N 61210 3-Acetyl-3a,8b-dihydroxy-2-methyl-3a,8b-dihydro-indeno[1,2-b]furan-4-one::3-acetyl-3a,8b-dihydroxy-2-methyl-4-indeno[1,2-b]furanone::3-acetyl-3a,8b-dihydroxy-2-methyl-indeno[1,2-b]furan-4-one::3-acetyl-3a,8b-dihydroxy-2-methylindeno[1,2-b]furan-4-one::3-ethanoyl-2-methyl-3a,8b-bis(oxidanyl)indeno[1,2-b]furan-4-one::MLS000768249::SMR000431570::cid_2828331 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=61210 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=61210&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 2828331 252640371 ZINC00507884 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120765 CCOC(=O)C1=C(C)OC2(O)c3ccccc3C(=O)C12O InChI=1S/C15H14O6/c1-3-20-13(17)11-8(2)21-15(19)10-7-5-4-6-9(10)12(16)14(11,15)18/h4-7,18-19H,3H2,1-2H3 UGGKRXKFQMVAEG-UHFFFAOYSA-N 64790 3a,8b-Dihydroxy-2-methyl-4-oxo-4,8b-dihydro-3aH-indeno[1,2-b]furan-3-carboxylic acid ethyl ester::3a,8b-dihydroxy-2-methyl-4-oxo-3-indeno[1,2-b]furancarboxylic acid ethyl ester::3a,8b-dihydroxy-4-keto-2-methyl-indeno[1,2-b]furan-3-carboxylic acid ethyl ester::MLS000768248::SMR000431569::cid_2828330::ethyl 2-methyl-3a,8b-bis(oxidanyl)-4-oxidanylidene-indeno[1,2-b]furan-3-carboxylate::ethyl 3a,8b-dihydroxy-2-methyl-4-oxoindeno[1,2-b]furan-3-carboxylate Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 49020 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64790&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 2828330 252643748 ZINC00187384 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120766 Nc1nc(SCC(O)=O)cc2c(C#N)c(nc(N)c12)N1CCCCC1 InChI=1S/C16H18N6O2S/c17-7-10-9-6-11(25-8-12(23)24)20-14(18)13(9)15(19)21-16(10)22-4-2-1-3-5-22/h6H,1-5,8H2,(H2,18,20)(H2,19,21)(H,23,24) BGYDUWHYSPAIGF-UHFFFAOYSA-N 46589 2-[(1,8-diamino-5-cyano-6-piperidin-1-yl-2,7-naphthyridin-3-yl)sulfanyl]acetic acid::2-[(1,8-diamino-5-cyano-6-piperidino-2,7-naphthyridin-3-yl)thio]acetic acid::2-[[1,8-bis(azanyl)-5-cyano-6-piperidin-1-yl-2,7-naphthyridin-3-yl]sulfanyl]ethanoic acid::2-[[1,8-diamino-5-cyano-6-(1-piperidinyl)-2,7-naphthyridin-3-yl]thio]acetic acid::MLS000773334::SMR000364051::cid_3327739 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 44079 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=46589 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=46589&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 3327739 252627140 ZINC25265399 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120767 COC(=O)CCC(=O)OC1(C)C(=O)C=C2C=C(C3CC3)N(C=C2C1=O)C1CCCC1 InChI=1S/C23H27NO6/c1-23(30-21(27)10-9-20(26)29-2)19(25)12-15-11-18(14-7-8-14)24(13-17(15)22(23)28)16-5-3-4-6-16/h11-14,16H,3-10H2,1-2H3 SJPMMUYFNDBMJH-UHFFFAOYSA-N 64791 4-O-(2-cyclopentyl-3-cyclopropyl-7-methyl-6,8-dioxoisoquinolin-7-yl) 1-O-methyl butanedioate::CMLD003523::MLS000438592::O4-[2-cyclopentyl-3-cyclopropyl-7-methyl-6,8-bis(oxidanylidene)isoquinolin-7-yl] O1-methyl butanedioate::SMR000452644::butanedioic acid O4-(2-cyclopentyl-3-cyclopropyl-7-methyl-6,8-dioxo-7-isoquinolinyl) ester O1-methyl ester::cid_16745570::succinic acid O4-(2-cyclopentyl-3-cyclopropyl-6,8-diketo-7-methyl-7-isoquinolyl) ester O1-methyl ester Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64791&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 16745570 252643749 ZINC13817205 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120768 COC(=O)CCC(=O)OC1(C)C(=O)C=C2C=C(C3CC3)N(CCCCO)C=C2C1=O InChI=1S/C22H27NO7/c1-22(30-20(27)8-7-19(26)29-2)18(25)12-15-11-17(14-5-6-14)23(9-3-4-10-24)13-16(15)21(22)28/h11-14,24H,3-10H2,1-2H3 XXIWCJHYACCRFZ-UHFFFAOYSA-N 64792 4-O-[3-cyclopropyl-2-(4-hydroxybutyl)-7-methyl-6,8-dioxoisoquinolin-7-yl] 1-O-methyl butanedioate::CMLD003552::MLS000438594::O4-[3-cyclopropyl-7-methyl-2-(4-oxidanylbutyl)-6,8-bis(oxidanylidene)isoquinolin-7-yl] O1-methyl butanedioate::SMR000452646::butanedioic acid O4-[3-cyclopropyl-2-(4-hydroxybutyl)-7-methyl-6,8-dioxo-7-isoquinolinyl] ester O1-methyl ester::cid_16745608::succinic acid O4-[3-cyclopropyl-2-(4-hydroxybutyl)-6,8-diketo-7-methyl-7-isoquinolyl] ester O1-methyl ester Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 57600 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64792&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 16745608 252643750 ZINC13817327 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120769 COC(=O)CCC(=O)OC1(C)C(=O)C=C2C=C(C3CC3)N(CC3CC3)C=C2C1=O InChI=1S/C22H25NO6/c1-22(29-20(26)8-7-19(25)28-2)18(24)10-15-9-17(14-5-6-14)23(11-13-3-4-13)12-16(15)21(22)27/h9-10,12-14H,3-8,11H2,1-2H3 STPBNYUWOIHWNL-UHFFFAOYSA-N 64793 4-O-[3-cyclopropyl-2-(cyclopropylmethyl)-7-methyl-6,8-dioxoisoquinolin-7-yl] 1-O-methyl butanedioate::CMLD004011::MLS000438609::O4-[3-cyclopropyl-2-(cyclopropylmethyl)-7-methyl-6,8-bis(oxidanylidene)isoquinolin-7-yl] O1-methyl butanedioate::SMR000452660::butanedioic acid O4-[3-cyclopropyl-2-(cyclopropylmethyl)-7-methyl-6,8-dioxo-7-isoquinolinyl] ester O1-methyl ester::cid_16745655::succinic acid O4-[3-cyclopropyl-2-(cyclopropylmethyl)-6,8-diketo-7-methyl-7-isoquinolyl] ester O1-methyl ester Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 63577 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64793&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 16745655 252643751 ZINC13817279 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120770 COC(=O)CCC(=O)OC1(C)C(=O)C=C2C=C(C3CC3)N(CCCOC(C)C)C=C2C1=O InChI=1S/C24H31NO7/c1-15(2)31-11-5-10-25-14-18-17(12-19(25)16-6-7-16)13-20(26)24(3,23(18)29)32-22(28)9-8-21(27)30-4/h12-16H,5-11H2,1-4H3 WEDNYZSWAYARFW-UHFFFAOYSA-N 64794 4-O-[3-cyclopropyl-7-methyl-6,8-dioxo-2-(3-propan-2-yloxypropyl)isoquinolin-7-yl] 1-O-methyl butanedioate::CMLD004055::MLS000438605::O4-[3-cyclopropyl-7-methyl-6,8-bis(oxidanylidene)-2-(3-propan-2-yloxypropyl)isoquinolin-7-yl] O1-methyl butanedioate::SMR000452656::butanedioic acid O4-[3-cyclopropyl-7-methyl-6,8-dioxo-2-(3-propan-2-yloxypropyl)-7-isoquinolinyl] ester O1-methyl ester::cid_16745656::succinic acid O4-[3-cyclopropyl-2-(3-isopropoxypropyl)-6,8-diketo-7-methyl-7-isoquinolyl] ester O1-methyl ester Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 32124 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64794&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 16745656 252643752 ZINC13817050 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120771 COC(=O)CCC(=O)OC1(C)C(=O)C(Br)=C2C=C(N(CC(C)C)C=C2C1=O)c1ccc(OC)cc1 InChI=1S/C26H28BrNO7/c1-15(2)13-28-14-19-18(12-20(28)16-6-8-17(33-4)9-7-16)23(27)25(32)26(3,24(19)31)35-22(30)11-10-21(29)34-5/h6-9,12,14-15H,10-11,13H2,1-5H3 MFAIIRGKMQBKFB-UHFFFAOYSA-N 64795 4-O-[5-bromo-3-(4-methoxyphenyl)-7-methyl-2-(2-methylpropyl)-6,8-dioxoisoquinolin-7-yl] 1-O-methyl butanedioate::CMLD004098::MLS001045834::O4-[5-bromanyl-3-(4-methoxyphenyl)-7-methyl-2-(2-methylpropyl)-6,8-bis(oxidanylidene)isoquinolin-7-yl] O1-methyl butanedioate::SMR000452731::butanedioic acid O4-[5-bromo-3-(4-methoxyphenyl)-7-methyl-2-(2-methylpropyl)-6,8-dioxo-7-isoquinolinyl] ester O1-methyl ester::cid_16745758::succinic acid O4-[5-bromo-2-isobutyl-6,8-diketo-3-(4-methoxyphenyl)-7-methyl-7-isoquinolyl] ester O1-methyl ester Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 28288 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64795 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64795&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 16745758 252643753 ZINC17596078 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120772 Cc1ccc(cc1C)C(=O)NC1(O)C(=O)c2ccccc2C1=O InChI=1S/C18H15NO4/c1-10-7-8-12(9-11(10)2)17(22)19-18(23)15(20)13-5-3-4-6-14(13)16(18)21/h3-9,23H,1-2H3,(H,19,22) TVSOMCJVQKDEQZ-UHFFFAOYSA-N 61226 3,4-dimethyl-N-[2-oxidanyl-1,3-bis(oxidanylidene)inden-2-yl]benzamide::MLS000830217::N-(2-hydroxy-1,3-diketo-indan-2-yl)-3,4-dimethyl-benzamide::N-(2-hydroxy-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)-3,4-dimethylbenzamide::N-(2-hydroxy-1,3-dioxo-2-indenyl)-3,4-dimethylbenzamide::N-(2-hydroxy-1,3-dioxoinden-2-yl)-3,4-dimethylbenzamide::SMR000458138::cid_2810379 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=61226 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=61226&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 2810379 252640387 ZINC00143724 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120773 OC1(NC(=O)c2c(Cl)cccc2Cl)C(=O)c2ccccc2C1=O InChI=1S/C16H9Cl2NO4/c17-10-6-3-7-11(18)12(10)15(22)19-16(23)13(20)8-4-1-2-5-9(8)14(16)21/h1-7,23H,(H,19,22) AFVBNYYWHQHUGU-UHFFFAOYSA-N 46593 2,6-bis(chloranyl)-N-[2-oxidanyl-1,3-bis(oxidanylidene)inden-2-yl]benzamide::2,6-dichloro-N-(2-hydroxy-1,3-diketo-indan-2-yl)benzamide::2,6-dichloro-N-(2-hydroxy-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)benzamide::2,6-dichloro-N-(2-hydroxy-1,3-dioxo-2-indenyl)benzamide::2,6-dichloro-N-(2-hydroxy-1,3-dioxoinden-2-yl)benzamide::MLS000830225::SMR000458146::cid_2810445 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=46593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=46593&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 2810445 252627144 ZINC01029980 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120774 OC1(NC(=O)c2ccc(cc2)C(F)(F)F)C(=O)c2ccccc2C1=O InChI=1S/C17H10F3NO4/c18-17(19,20)10-7-5-9(6-8-10)15(24)21-16(25)13(22)11-3-1-2-4-12(11)14(16)23/h1-8,25H,(H,21,24) MCLXGPFUHLXFEK-UHFFFAOYSA-N 64796 MLS000861878::N-(2-hydroxy-1,3-diketo-indan-2-yl)-4-(trifluoromethyl)benzamide::N-(2-hydroxy-1,3-dioxo-2-indenyl)-4-(trifluoromethyl)benzamide::N-(2-hydroxy-1,3-dioxoinden-2-yl)-4-(trifluoromethyl)benzamide::N-[2-oxidanyl-1,3-bis(oxidanylidene)inden-2-yl]-4-(trifluoromethyl)benzamide::N1-(2-hydroxy-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)-4-(trifluoromethyl)benzamide::SMR000460662::cid_2732881 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64796&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 2732881 252643754 ZINC00103174 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120775 COC(=O)CCC(=O)OC1(C)C(=O)C(Br)=C2C=C(N(C=C2C1=O)C1CC1)c1ccc(OC)cc1 InChI=1S/C25H24BrNO7/c1-25(34-21(29)11-10-20(28)33-3)23(30)18-13-27(15-6-7-15)19(12-17(18)22(26)24(25)31)14-4-8-16(32-2)9-5-14/h4-5,8-9,12-13,15H,6-7,10-11H2,1-3H3 ZWILRIIIGUBNDA-UHFFFAOYSA-N 43838 4-O-[5-bromo-2-cyclopropyl-3-(4-methoxyphenyl)-7-methyl-6,8-dioxoisoquinolin-7-yl] 1-O-methyl butanedioate::CMLD004038::Glucosamine derivative, 11::MLS000438679::O4-[5-bromanyl-2-cyclopropyl-3-(4-methoxyphenyl)-7-methyl-6,8-bis(oxidanylidene)isoquinolin-7-yl] O1-methyl butanedioate::SMR000452728::butanedioic acid O4-[5-bromo-2-cyclopropyl-3-(4-methoxyphenyl)-7-methyl-6,8-dioxo-7-isoquinolinyl] ester O1-methyl ester::cid_16759689::succinic acid O4-[5-bromo-2-cyclopropyl-6,8-diketo-3-(4-methoxyphenyl)-7-methyl-7-isoquinolyl] ester O1-methyl ester Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 46188 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=43838 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=43838&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 16759689 123080196 ZINC17654274 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120776 O=c1[nH]c(Nc2ccccc2)cc2ccccc12 InChI=1S/C15H12N2O/c18-15-13-9-5-4-6-11(13)10-14(17-15)16-12-7-2-1-3-8-12/h1-10H,(H2,16,17,18) UZQIOQVHUUAJOZ-UHFFFAOYSA-N 34182 3-anilino-2H-isoquinolin-1-one::3-anilinoisocarbostyril::3-anilinoisoquinolin-1(2H)-one::3-phenylazanyl-2H-isoquinolin-1-one::MLS000043701::SMR000020713::cid_2142225 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34182 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34182&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 2142225 252616869 ZINC08578180 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120777 CCCOc1cc2c(C#N)c(nc(N)c2c(N)n1)N1CCCC1 InChI=1S/C16H20N6O/c1-2-7-23-12-8-10-11(9-17)16(22-5-3-4-6-22)21-15(19)13(10)14(18)20-12/h8H,2-7H2,1H3,(H2,18,20)(H2,19,21) SFOWVXGRGNFIHI-UHFFFAOYSA-N 64797 1,8-bis(azanyl)-6-propoxy-3-pyrrolidin-1-yl-2,7-naphthyridine-4-carbonitrile::1,8-diamino-6-propoxy-3-(1-pyrrolidinyl)-2,7-naphthyridine-4-carbonitrile::1,8-diamino-6-propoxy-3-pyrrolidin-1-yl-2,7-naphthyridine-4-carbonitrile::1,8-diamino-6-propoxy-3-pyrrolidino-2,7-naphthyridine-4-carbonitrile::MLS000541660::SMR000472233::cid_11958363 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64797&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 11958363 252643755 ZINC15974472 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120778 Brc1ccc2c(c1)cc(Nc1ccccc1)[nH]c2=O InChI=1S/C15H11BrN2O/c16-11-6-7-13-10(8-11)9-14(18-15(13)19)17-12-4-2-1-3-5-12/h1-9H,(H2,17,18,19) XFUGVANZIRUHLB-UHFFFAOYSA-N 64798 3-anilino-6-bromo-2H-isoquinolin-1-one::3-anilino-6-bromo-isocarbostyril::6-bromanyl-3-phenylazanyl-2H-isoquinolin-1-one::MLS000541775::SMR000472405::cid_16727376 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 46923 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64798&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 16727376 252643756 ZINC15952502 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120779 COc1cc(Br)c(cc1OC)C(=O)c1nccc2cc(OC)c(OC)cc12 InChI=1S/C20H18BrNO5/c1-24-15-7-11-5-6-22-19(12(11)8-16(15)25-2)20(23)13-9-17(26-3)18(27-4)10-14(13)21/h5-10H,1-4H3 KNIHFXMFUCCLGH-UHFFFAOYSA-N 61232 (2-bromanyl-4,5-dimethoxy-phenyl)-(6,7-dimethoxyisoquinolin-1-yl)methanone::(2-bromo-4,5-dimethoxy-phenyl)-(6,7-dimethoxy-1-isoquinolyl)methanone::(2-bromo-4,5-dimethoxyphenyl)(6,7-dimethoxy-1-isoquinolinyl)methanone::(2-bromo-4,5-dimethoxyphenyl)-(6,7-dimethoxy-1-isoquinolinyl)methanone::(2-bromo-4,5-dimethoxyphenyl)-(6,7-dimethoxyisoquinolin-1-yl)methanone::MLS001001832::SMR000498332::cid_2974206 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 52139 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=61232 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=61232&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 2974206 252640393 ZINC13152931 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120780 NS(=O)(=O)c1ccc(NC2=CC(=O)C(=O)c3ccccc23)cc1 InChI=1S/C16H12N2O4S/c17-23(21,22)11-7-5-10(6-8-11)18-14-9-15(19)16(20)13-4-2-1-3-12(13)14/h1-9,18H,(H2,17,21,22) DIHFBNUDSJVTRQ-UHFFFAOYSA-N 61233 4-[(3,4-diketo-1-naphthyl)amino]benzenesulfonamide::4-[(3,4-dioxo-1-naphthalenyl)amino]benzenesulfonamide::4-[(3,4-dioxo-3,4-dihydro-1-naphthalenyl)amino]benzenesulfonamide::4-[(3,4-dioxonaphthalen-1-yl)amino]benzenesulfonamide::4-[[3,4-bis(oxidanylidene)naphthalen-1-yl]amino]benzenesulfonamide::MLS001164435::SMR000496650::cid_367783 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 38859 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=61233 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=61233&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 367783 252640394 ZINC01625324 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120781 CN1C2ON(C)CC[C@@]2(C)c2cc(O)ccc12 InChI=1S/C13H18N2O2/c1-13-6-7-14(2)17-12(13)15(3)11-5-4-9(16)8-10(11)13/h4-5,8,12,16H,6-7H2,1-3H3/t12?,13-/m0/s1 OPAXVHIAQIXNAM-ABLWVSNPSA-N 64799 (4aS)-2,4a,9-trimethyl-2,3,4,4a,9,9a-hexahydro-[1,2]oxazino[6,5-b]indol-6-ol::(4aS)-2,4a,9-trimethyl-4,9a-dihydro-3H-[1,2]oxazino[6,5-b]indol-6-ol::(4aS)-2,4a,9-trimethyl-4,9a-dihydro-3H-oxazin[6,5-b]indol-6-ol::(4aS)-2,4a,9-trimethyl-4,9a-dihydro-3H-oxazino[6,5-b]indol-6-ol::MLS001060820::SMR000486281::cid_24747147 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 52346 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64799&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 24747147 252643757 ZINC12480611 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120782 OC(=O)c1ccc(cc1)S(=O)(=O)N=C1C=C(Nc2ccccc2F)C(=O)c2ccccc12 InChI=1S/C23H15FN2O5S/c24-18-7-3-4-8-19(18)25-21-13-20(16-5-1-2-6-17(16)22(21)27)26-32(30,31)15-11-9-14(10-12-15)23(28)29/h1-13,25H,(H,28,29) LWAKZCIYRXJCJV-UHFFFAOYSA-N 48030 4-[(E)-[3-(2-fluoroanilino)-4-keto-1-naphthylidene]amino]sulfonylbenzoic acid::4-[(E)-[3-(2-fluoroanilino)-4-oxo-1-naphthalenylidene]amino]sulfonylbenzoic acid::4-[(E)-[3-(2-fluoroanilino)-4-oxonaphthalen-1-ylidene]amino]sulfonylbenzoic acid::4-[(E)-[3-[(2-fluorophenyl)amino]-4-oxidanylidene-naphthalen-1-ylidene]amino]sulfonylbenzoic acid::MLS000948172::SMR000620457::cid_6023694 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 15546 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48030&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 6023694 252628328 ZINC01926319 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120783 CCc1ccc(cc1)S(=O)(=O)N=C1C=C(Nc2cccc(c2)C(O)=O)C(=O)c2ccccc12 InChI=1S/C25H20N2O5S/c1-2-16-10-12-19(13-11-16)33(31,32)27-22-15-23(24(28)21-9-4-3-8-20(21)22)26-18-7-5-6-17(14-18)25(29)30/h3-15,26H,2H2,1H3,(H,29,30) RYVRPCQNGCQISY-UHFFFAOYSA-N 48036 3-[[(4E)-4-(4-ethylphenyl)sulfonylimino-1-keto-2-naphthyl]amino]benzoic acid::3-[[(4E)-4-(4-ethylphenyl)sulfonylimino-1-oxidanylidene-naphthalen-2-yl]amino]benzoic acid::3-[[(4E)-4-(4-ethylphenyl)sulfonylimino-1-oxo-2-naphthalenyl]amino]benzoic acid::3-[[(4E)-4-(4-ethylphenyl)sulfonylimino-1-oxonaphthalen-2-yl]amino]benzoic acid::MLS000948071::SMR000620248::cid_5824727 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 22658 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48036 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48036&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 5824727 252628334 ZINC00944513 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120784 Cc1ccc(c(C)c1)S(=O)(=O)N=C1C=C(Nc2cccc(c2)C(O)=O)C(=O)c2ccccc12 InChI=1S/C25H20N2O5S/c1-15-10-11-23(16(2)12-15)33(31,32)27-21-14-22(24(28)20-9-4-3-8-19(20)21)26-18-7-5-6-17(13-18)25(29)30/h3-14,26H,1-2H3,(H,29,30) RUWHEBZPTCVEMQ-UHFFFAOYSA-N 48039 3-[[(4E)-4-(2,4-dimethylphenyl)sulfonylimino-1-keto-2-naphthyl]amino]benzoic acid::3-[[(4E)-4-(2,4-dimethylphenyl)sulfonylimino-1-oxidanylidene-naphthalen-2-yl]amino]benzoic acid::3-[[(4E)-4-(2,4-dimethylphenyl)sulfonylimino-1-oxo-2-naphthalenyl]amino]benzoic acid::3-[[(4E)-4-(2,4-dimethylphenyl)sulfonylimino-1-oxonaphthalen-2-yl]amino]benzoic acid::MLS000948061::SMR000620247::cid_5824726 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 27075 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48039&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 5824726 252628337 ZINC00944511 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120785 [O-][N+]1=C(C(=O)c2ccccc12)c1ccccc1 InChI=1S/C14H9NO2/c16-14-11-8-4-5-9-12(11)15(17)13(14)10-6-2-1-3-7-10/h1-9H WXFLHMJSSLDOPA-UHFFFAOYSA-N 64800 1-oxidanidyl-2-phenyl-indol-1-ium-3-one::1-oxido-2-phenyl-3-indol-1-iumone::1-oxido-2-phenyl-indol-1-ium-3-one::1-oxido-2-phenylindol-1-ium-3-one::MLS001241052::SMR000841197::cid_74787 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 2667 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64800&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 74787 252643758 ZINC01723988 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120786 COc1ccc(Cn2c(N)c(C(=O)NCc3ccco3)c3nc4ccccc4nc23)cc1OC InChI=1S/C25H23N5O4/c1-32-19-10-9-15(12-20(19)33-2)14-30-23(26)21(25(31)27-13-16-6-5-11-34-16)22-24(30)29-18-8-4-3-7-17(18)28-22/h3-12H,13-14,26H2,1-2H3,(H,27,31) FJHSDGISPUKBLU-UHFFFAOYSA-N 64801 2-amino-1-[(3,4-dimethoxyphenyl)methyl]-N-(2-furanylmethyl)-3-pyrrolo[3,2-b]quinoxalinecarboxamide::2-amino-1-[(3,4-dimethoxyphenyl)methyl]-N-(furan-2-ylmethyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide::2-amino-N-(2-furfuryl)-1-veratryl-pyrrolo[3,2-b]quinoxaline-3-carboxamide::2-azanyl-1-[(3,4-dimethoxyphenyl)methyl]-N-(furan-2-ylmethyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide::MLS001305721::SMR000045376::cid_664512 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64801 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64801&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 664512 252643759 ZINC02393369 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 120787 COc1ccc(cc1OC)C(=O)c1nccc2cc(OC)c(OC)cc12 InChI=1S/C20H19NO5/c1-23-15-6-5-13(10-16(15)24-2)20(22)19-14-11-18(26-4)17(25-3)9-12(14)7-8-21-19/h5-11H,1-4H3 QJTBIAMBPGGIGI-UHFFFAOYSA-N 64802 (6,7-dimethoxy-1-isoquinolinyl)-(3,4-dimethoxyphenyl)methanone::(6,7-dimethoxy-1-isoquinolyl)-(3,4-dimethoxyphenyl)methanone::(6,7-dimethoxyisoquinolin-1-yl)-(3,4-dimethoxyphenyl)methanone::MLS001360484::SMR001223913::cid_96932 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 67047 PubChem 10.7270/Q27M06CD aid2394 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64802&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 96932 252643760 ZINC01609699 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 50229624 Cc1cc(OCCCONC(N)=N)cc(OS(=O)(=O)c2ccccc2S(C)(=O)=O)c1 InChI=1S/C18H23N3O7S2/c1-13-10-14(26-8-5-9-27-21-18(19)20)12-15(11-13)28-30(24,25)17-7-4-3-6-16(17)29(2,22)23/h3-4,6-7,10-12H,5,8-9H2,1-2H3,(H4,19,20,21) CFBZFBMYIQZREO-UHFFFAOYSA-N 50126635 3-[3-({[(Z)-amino(imino)methyl]amino}oxy)ethoxy]-5-methylphenyl 2-methylsulfonylbenzenesulfonate::3-[3-({[(Z)-amino(imino)methyl]amino}oxy)propoxy]-5-methylphenyl 2-methylsulfonylbenzenesulfonate::CHEMBL37637 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens >67000 ChEMBL 10.1016/s0960-894x(03)00125-2 10.7270/Q2668CJ9 12668020 Tomczuk, B; Lu, T; Soll, RM; Fedde, C; Wang, A; Murphy, L; Crysler, C; Dasgupta, M; Eisennagel, S; Spurlino, J; Bone, R 3-Dimensional Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126635 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126635&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 9955758 104018710 CHEMBL37637 ZINC29306174 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161 51111319 CC(C)C[C@@H]1NC(=O)[C@@H](C)NC(=O)CN(C)C(=O)CC[C@@H](NC(=O)[C@@H](C)[C@H](C)NC(=O)[C@H](Cc2ccccc2)NC(=O)C[C@@H](NC1=O)C(O)=O)C(O)=O InChI=1S/C35H51N7O11/c1-18(2)14-24-33(49)41-26(35(52)53)16-27(43)38-25(15-22-10-8-7-9-11-22)32(48)37-20(4)19(3)30(46)39-23(34(50)51)12-13-29(45)42(6)17-28(44)36-21(5)31(47)40-24/h7-11,18-21,23-26H,12-17H2,1-6H3,(H,36,44)(H,37,48)(H,38,43)(H,39,46)(H,40,47)(H,41,49)(H,50,51)(H,52,53)/t19-,20-,21+,23+,24-,25-,26+/m0/s1 ZCDKYAHFMSVFHS-ZWUHPVAQSA-N 50453860 CHEMBL4210922 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit Homo sapiens 253500 ChEMBL 10.1016/j.bmc.2017.08.040 10.7270/Q2N58PZ3 28893598 Fontanillo, M; Köhn, M European Molecular Biology Laboratory (EMBL) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000369&target=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453860&enzyme=Serine%2Fthreonine-protein+phosphatase+PP1-alpha+catalytic+subunit&column=ki&startPg=0&Increment=50&submit=Search 145964099 433922292 1 MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK 1FJM,1S70,1U32,3EGG,3EGH,3HVQ,3N5U,3V4Y,4G9J,6DCX,6G0I,6G0J,6GHM,6OBN,6OBP,6ZEH,6ZEJ,7TVF,7UPI Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PP1A_HUMAN P62136 A6NNR3 B2R908 P08129 P20653 P22802 Q07161