BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 50278006 Oc1ccc(cc1)-c1cc(=O)c2c(O)c(O)c(O)cc2o1 InChI=1S/C15H10O6/c16-8-3-1-7(2-4-8)11-5-9(17)13-12(21-11)6-10(18)14(19)15(13)20/h1-6,16,18-20H JVXZRQGOGOXCEC-UHFFFAOYSA-N 23411 5,6,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one::Scutel-larei::Scutellarein::Scutellarein (2)::Scutellarein (28)::US10252984, Table 2.2 Succinate-semialdehyde dehydrogenase, mitochondrial Homo sapiens 7200000 ChEMBL 10.1016/j.ejmech.2014.07.013 10.7270/Q2GH9KMN 25019478 Singh, M; Kaur, M; Silakari, O Punjabi University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23411 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000277&target=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23411&enzyme=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 5281697 50091675 9062 C10184 ZINC05842416 1 MATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLRCYAGRLAGLSAALLRTDSFVGGRWLPAAATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGDIIHTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYVCYGGL 2W8N,2W8O Succinate-semialdehyde dehydrogenase, mitochondrial SSDH_HUMAN P51649 B2RD26 G5E949 Q546H9 Q8N3W6 50328391 OC[C@H]1O[C@@H](Oc2ccc(C=O)cc2)[C@H](O)[C@H](O)[C@@H]1O InChI=1S/C13H16O7/c14-5-7-1-3-8(4-2-7)19-13-12(18)11(17)10(16)9(6-15)20-13/h1-5,9-13,15-18H,6H2/t9-,10-,11-,12-,13-/m1/s1 OLZAGZCCJJBKNZ-SYLRKERUSA-N 50177404 4-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-tetrahydro-2H-pyran-2-yloxy)benzaldehyde::4-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)benzaldehyde::CHEMBL201358::Helicide Succinate-semialdehyde dehydrogenase, mitochondrial Homo sapiens >1000000 ChEMBL 10.1016/j.bmcl.2005.10.040 10.7270/Q29G5MCH 16290145 Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177404 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000277&target=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177404&enzyme=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 12896796 104062872 CHEMBL201358 ZINC28568062 1 MATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLRCYAGRLAGLSAALLRTDSFVGGRWLPAAATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGDIIHTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYVCYGGL 2W8N,2W8O Succinate-semialdehyde dehydrogenase, mitochondrial SSDH_HUMAN P51649 B2RD26 G5E949 Q546H9 Q8N3W6 50328392 COc1cc(C=O)ccc1O InChI=1S/C8H8O3/c1-11-8-4-6(5-9)2-3-7(8)10/h2-5,10H,1H3 MWOOGOJBHIARFG-UHFFFAOYSA-N 50177405 3-methoxy-4-hydroxybenzaldehyde::4-hydroxy-3-methoxybenzaldehyde::4-hydroxy-m-anisaldehyde::CHEMBL13883::p-hydroxy-m-methoxybenzaldehyde::p-vanillin::vanillin Succinate-semialdehyde dehydrogenase, mitochondrial Homo sapiens 15600 ChEMBL 10.1016/j.bmcl.2005.10.040 10.7270/Q29G5MCH 16290145 Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177405 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000277&target=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177405&enzyme=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search V55 2VSU,2VSS,5OMR,6XM9,7R0S,7R0U,7XWV,5J55,4RGS,6HOU,6HOP,6YCT,6YCK,6YCL,6YCM,5FXP 1183 104062873 18346 CHEMBL13883 6412 C00755 ZINC02567933 1 MATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLRCYAGRLAGLSAALLRTDSFVGGRWLPAAATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGDIIHTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYVCYGGL 2W8N,2W8O Succinate-semialdehyde dehydrogenase, mitochondrial SSDH_HUMAN P51649 B2RD26 G5E949 Q546H9 Q8N3W6 50328393 COc1ccc(C=O)cc1 InChI=1S/C8H8O2/c1-10-8-4-2-7(6-9)3-5-8/h2-6H,1H3 ZRSNZINYAWTAHE-UHFFFAOYSA-N 50139370 4-Methoxy-benzaldehyde::4-methoxybenzaldehyde::CHEMBL161598 Succinate-semialdehyde dehydrogenase, mitochondrial Homo sapiens >1000000 ChEMBL 10.1016/j.bmcl.2005.10.040 10.7270/Q29G5MCH 16290145 Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139370 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000277&target=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139370&enzyme=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 31244 104029263 CHEMBL161598 C10761 ZINC00157146 1 MATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLRCYAGRLAGLSAALLRTDSFVGGRWLPAAATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGDIIHTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYVCYGGL 2W8N,2W8O Succinate-semialdehyde dehydrogenase, mitochondrial SSDH_HUMAN P51649 B2RD26 G5E949 Q546H9 Q8N3W6 50328394 Oc1ccc(cc1)C(=O)C=C InChI=1S/C9H8O2/c1-2-9(11)7-3-5-8(10)6-4-7/h2-6,10H,1H2 NKPPNPJUBLEKAD-UHFFFAOYSA-N 50177407 1-(4-hydroxyphenyl)prop-2-en-1-one::4-acryloylphenol::CHEMBL378577 Succinate-semialdehyde dehydrogenase, mitochondrial Homo sapiens 350 ChEMBL 10.1016/j.bmcl.2005.10.040 10.7270/Q29G5MCH 16290145 Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177407 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000277&target=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177407&enzyme=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 16036927 104062875 CHEMBL378577 ZINC28567957 1 MATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLRCYAGRLAGLSAALLRTDSFVGGRWLPAAATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGDIIHTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYVCYGGL 2W8N,2W8O Succinate-semialdehyde dehydrogenase, mitochondrial SSDH_HUMAN P51649 B2RD26 G5E949 Q546H9 Q8N3W6 50328395 Oc1ccc(CN=O)cc1 InChI=1S/C7H7NO2/c9-7-3-1-6(2-4-7)5-8-10/h1-4,9H,5H2 UCMJYLGFDFZTDU-UHFFFAOYSA-N 50177406 4-hydroxybenzaldehyde oxime::CHEMBL202611 Succinate-semialdehyde dehydrogenase, mitochondrial Homo sapiens >1000000 ChEMBL 10.1016/j.bmcl.2005.10.040 10.7270/Q29G5MCH 16290145 Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177406 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000277&target=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177406&enzyme=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search OX5 2OOZ 54346225 104062874 CHEMBL202611 ZINC04578804 1 MATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLRCYAGRLAGLSAALLRTDSFVGGRWLPAAATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGDIIHTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYVCYGGL 2W8N,2W8O Succinate-semialdehyde dehydrogenase, mitochondrial SSDH_HUMAN P51649 B2RD26 G5E949 Q546H9 Q8N3W6 50328397 OCc1ccc(O)cc1 InChI=1S/C7H8O2/c8-5-6-1-3-7(9)4-2-6/h1-4,8-9H,5H2 BVJSUAQZOZWCKN-UHFFFAOYSA-N 50177408 4-(hydroxymethyl)phenol::4-Hydroxybenzyl alcohol::4HBA::CHEMBL202132::parahydroxybenzyl alcohol Succinate-semialdehyde dehydrogenase, mitochondrial Homo sapiens >1000000 ChEMBL 10.1016/j.bmcl.2005.10.040 10.7270/Q29G5MCH 16290145 Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177408 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000277&target=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177408&enzyme=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 125 104062876 67410 CHEMBL202132 C17467 ZINC00388762 1 MATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLRCYAGRLAGLSAALLRTDSFVGGRWLPAAATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGDIIHTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYVCYGGL 2W8N,2W8O Succinate-semialdehyde dehydrogenase, mitochondrial SSDH_HUMAN P51649 B2RD26 G5E949 Q546H9 Q8N3W6 50328401 Oc1ccc(C=O)cc1 InChI=1S/C7H6O2/c8-5-6-1-3-7(9)4-2-6/h1-5,9H RGHHSNMVTDWUBI-UHFFFAOYSA-N 50177411 4-formylphenol::4-hydroxybenzaldehyde::CHEMBL14193::p-formylphenol Succinate-semialdehyde dehydrogenase, mitochondrial Homo sapiens 24700 ChEMBL 10.1016/j.bmcl.2005.10.040 10.7270/Q29G5MCH 16290145 Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177411 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000277&target=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177411&enzyme=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search HBA 1Z42,4TMC,7PHO,1OYB,4JQN,3ZOE,3ZOC,1EB9,2VQ5,7OFT,1K03,3ATZ,5V4P,4RNV,5DY3,2GQ9,3HGJ,5E4M,7ETI,4JIP,5K1K,6S31 126 104062879 17597 CHEMBL14193 DB03560 C00633 ZINC00156709 1 MATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLRCYAGRLAGLSAALLRTDSFVGGRWLPAAATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGDIIHTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYVCYGGL 2W8N,2W8O Succinate-semialdehyde dehydrogenase, mitochondrial SSDH_HUMAN P51649 B2RD26 G5E949 Q546H9 Q8N3W6 50328402 NCc1ccc(O)cc1 InChI=1S/C7H9NO/c8-5-6-1-3-7(9)4-2-6/h1-4,9H,5,8H2 RQJDUEKERVZLLU-UHFFFAOYSA-N 50177412 4-(aminomethyl)phenol::4-hydroxybenzylamine::CHEMBL202519 Succinate-semialdehyde dehydrogenase, mitochondrial Homo sapiens >1000000 ChEMBL 10.1016/j.bmcl.2005.10.040 10.7270/Q29G5MCH 16290145 Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177412 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000277&target=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177412&enzyme=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 97472 104062880 50336 CHEMBL202519 ZINC00153933 1 MATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLRCYAGRLAGLSAALLRTDSFVGGRWLPAAATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGDIIHTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYVCYGGL 2W8N,2W8O Succinate-semialdehyde dehydrogenase, mitochondrial SSDH_HUMAN P51649 B2RD26 G5E949 Q546H9 Q8N3W6 50328403 COc1cc(CN=O)ccc1O InChI=1S/C8H9NO3/c1-12-8-4-6(5-9-11)2-3-7(8)10/h2-4,10H,5H2,1H3 GLXIIOGHIFKSBY-UHFFFAOYSA-N 50177413 4-hydroxy-3-methoxybenzaldehyde oxime::CHEMBL202440 Succinate-semialdehyde dehydrogenase, mitochondrial Homo sapiens >1000000 ChEMBL 10.1016/j.bmcl.2005.10.040 10.7270/Q29G5MCH 16290145 Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177413 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000277&target=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177413&enzyme=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 53845260 104062881 CHEMBL202440 ZINC18217828 1 MATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLRCYAGRLAGLSAALLRTDSFVGGRWLPAAATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGDIIHTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYVCYGGL 2W8N,2W8O Succinate-semialdehyde dehydrogenase, mitochondrial SSDH_HUMAN P51649 B2RD26 G5E949 Q546H9 Q8N3W6 50328406 CC(=O)c1ccc(O)cc1 InChI=1S/C8H8O2/c1-6(9)7-2-4-8(10)5-3-7/h2-5,10H,1H3 TXFPEBPIARQUIG-UHFFFAOYSA-N 50177409 (4-hydroxyphenyl)ethan-1-one::1-(4-hydroxyphenyl)ethanone::4'-hydroxyacetophenone::4-Acetylphenol::4-Hydroxyacetophenone::CHEMBL201083::Methyl p-hydroxyphenyl ketone::p-Hydroxyacetophenone::p-Hydroxyphenyl methyl ketone::para-Hydroxyacetophenone Succinate-semialdehyde dehydrogenase, mitochondrial Homo sapiens 166000 ChEMBL 10.1016/j.bmcl.2005.10.040 10.7270/Q29G5MCH 16290145 Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177409 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000277&target=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177409&enzyme=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search AC6 7FKN,5CQ8,5PHN,2O48,2GQ8,5PB8 7469 104062877 28032 CHEMBL201083 C10700 ZINC00330136 1 MATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLRCYAGRLAGLSAALLRTDSFVGGRWLPAAATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGDIIHTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYVCYGGL 2W8N,2W8O Succinate-semialdehyde dehydrogenase, mitochondrial SSDH_HUMAN P51649 B2RD26 G5E949 Q546H9 Q8N3W6 50328408 OC(=O)c1ccc(O)cc1 InChI=1S/C7H6O3/c8-6-3-1-5(2-4-6)7(9)10/h1-4,8H,(H,9,10) FJKROLUGYXJWQN-UHFFFAOYSA-N 26194 4-Hydroxybenzoate, III::4-hydroxybenzoic acid::CHEMBL441343::p-Hydroxybenzoic acid::phenol derivative, 8 Succinate-semialdehyde dehydrogenase, mitochondrial Homo sapiens >1000000 ChEMBL 10.1016/j.bmcl.2005.10.040 10.7270/Q29G5MCH 16290145 Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26194 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000277&target=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26194&enzyme=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search PHB 2BUW,2BUR,1G81,1BKW,6KCL,6KCM,6KCK,1IUW,1IUV,1IUX,1PXB,1PDH,3ZYB,1G1B,1CJ2,1Q4S,5D2A,4LKE,4LKD,4LKF,4OD5,1CC4,1PBE,1BF3,4EVS,4EVQ,4EY3,3TYB,1BGJ,1BGN,1DOB,1DOC,5IGA,2PHH,1PXA,7CUO,1K0I,4F06,3PCC,5I5P,1CJ3,7DQB,1TT8,6AL9,1JD3,1PXC,1CC6,1YKJ,3HGR,3HGS,1D7L,5RTJ,4E3G,1CJ4,3R3A,3R36,1FW9,7ON9,5W1E,5M21 135 56464631 30763 CHEMBL441343 DB04242 C00156 ZINC00332752 1 MATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLRCYAGRLAGLSAALLRTDSFVGGRWLPAAATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGDIIHTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYVCYGGL 2W8N,2W8O Succinate-semialdehyde dehydrogenase, mitochondrial SSDH_HUMAN P51649 B2RD26 G5E949 Q546H9 Q8N3W6 50328409 OC[C@H]1O[C@@H](Oc2ccc(CO)cc2)[C@H](O)[C@@H](O)[C@@H]1O InChI=1S/C13H18O7/c14-5-7-1-3-8(4-2-7)19-13-12(18)11(17)10(16)9(6-15)20-13/h1-4,9-18H,5-6H2/t9-,10-,11+,12-,13-/m1/s1 PUQSUZTXKPLAPR-UJPOAAIJSA-N 50177403 (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(4-(hydroxymethyl)phenoxy)-tetrahydro-2H-pyran-3,4,5-triol::CHEMBL274739 Succinate-semialdehyde dehydrogenase, mitochondrial Homo sapiens >1000000 ChEMBL 10.1016/j.bmcl.2005.10.040 10.7270/Q29G5MCH 16290145 Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177403 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000277&target=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177403&enzyme=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 115067 104062871 CHEMBL274739 C03400 ZINC03881790 1 MATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLRCYAGRLAGLSAALLRTDSFVGGRWLPAAATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGDIIHTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYVCYGGL 2W8N,2W8O Succinate-semialdehyde dehydrogenase, mitochondrial SSDH_HUMAN P51649 B2RD26 G5E949 Q546H9 Q8N3W6 50328411 CCC(=O)c1ccc(O)cc1 InChI=1S/C9H10O2/c1-2-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H3 RARSHUDCJQSEFJ-UHFFFAOYSA-N 50177402 1-(4-hydroxy-phenyl)-propan-1-one::1-(4-hydroxyphenyl)propan-1-one::4'-Hydroxypropiophenone::CHEMBL312311::Paroxypropione Succinate-semialdehyde dehydrogenase, mitochondrial Homo sapiens 293000 ChEMBL 10.1016/j.bmcl.2005.10.040 10.7270/Q29G5MCH 16290145 Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177402 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000277&target=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177402&enzyme=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 6271 104062870 CHEMBL312311 C13342 ZINC00001890 1 MATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLRCYAGRLAGLSAALLRTDSFVGGRWLPAAATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGDIIHTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYVCYGGL 2W8N,2W8O Succinate-semialdehyde dehydrogenase, mitochondrial SSDH_HUMAN P51649 B2RD26 G5E949 Q546H9 Q8N3W6 50328413 Oc1ccc(C=O)cc1[N+]([O-])=O InChI=1S/C7H5NO4/c9-4-5-1-2-7(10)6(3-5)8(11)12/h1-4,10H YTHJCZRFJGXPTL-UHFFFAOYSA-N 50177410 4-hydroxy-3-nitrobenzaldehyde::CHEMBL378361 Succinate-semialdehyde dehydrogenase, mitochondrial Homo sapiens 33100 ChEMBL 10.1016/j.bmcl.2005.10.040 10.7270/Q29G5MCH 16290145 Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177410 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000277&target=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177410&enzyme=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 18169 104062878 CHEMBL378361 ZINC00562702 1 MATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLRCYAGRLAGLSAALLRTDSFVGGRWLPAAATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGDIIHTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYVCYGGL 2W8N,2W8O Succinate-semialdehyde dehydrogenase, mitochondrial SSDH_HUMAN P51649 B2RD26 G5E949 Q546H9 Q8N3W6 50328414 Nc1ccc(cc1)C(O)=O InChI=1S/C7H7NO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,8H2,(H,9,10) ALYNCZNDIQEVRV-UHFFFAOYSA-N 50145829 4-Aminobenzoesaeure::4-aminobenzoic acid::CHEMBL542::PABA::p-Aminobenzoesaeure::p-aminobenzoic acid::para-aminobenzoic acid Succinate-semialdehyde dehydrogenase, mitochondrial Homo sapiens >1000000 ChEMBL 10.1016/j.bmcl.2005.10.040 10.7270/Q29G5MCH 16290145 Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145829 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000277&target=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145829&enzyme=Succinate-semialdehyde+dehydrogenase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search PAB 1IUU,1IUT,1IUS,7S2K,8SCD,3Q2A,6DAY,1PBD,7R86,3TYZ,5Z79,2DZA,7PD5 978 104034518 30753 CHEMBL542 DB02362 C00568 ZINC00000920 1 MATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLRCYAGRLAGLSAALLRTDSFVGGRWLPAAATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGDIIHTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYVCYGGL 2W8N,2W8O Succinate-semialdehyde dehydrogenase, mitochondrial SSDH_HUMAN P51649 B2RD26 G5E949 Q546H9 Q8N3W6