BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 50032598 OC(=O)CNC(=S)Nc1ccccc1 InChI=1S/C9H10N2O2S/c12-8(13)6-10-9(14)11-7-4-2-1-3-5-7/h1-5H,6H2,(H,12,13)(H2,10,11,14) UWTLARNSDZXILM-UHFFFAOYSA-N 50021645 (3-Phenyl-thioureido)-acetic acid::CHEMBL311337::N-Phenylthiohydantoic acid 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 91000 ChEMBL 10.1021/jm00385a003 10.7270/Q2SF2V5K 3027337 Wermuth, CG; Bourguignon, JJ; Schlewer, G; Gies, JP; Schoenfelder, A; Melikian, A; Bouchet, MJ; Chantreux, D; Molimard, JC; Heaulme, M TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021645 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021645&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 3000722 103932343 CHEMBL311337 ZINC19899035 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50037235 [NH3+]C\C=C(/CF)C([O-])=O InChI=1S/C5H8FNO2/c6-3-4(1-2-7)5(8)9/h1H,2-3,7H2,(H,8,9)/b4-1+ YAOAKJZTKSOIOL-DAFODLJHSA-N 50024968 (2Z)-4-ammonio-2-(fluoromethyl)but-2-enoate::CHEMBL353363 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 9000 ChEMBL 10.1021/jm00155a029 10.7270/Q2668C6T 3701787 Silverman, RB; Durkee, SC; Invergo, BJ TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024968 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024968&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 44378094 103934938 58001 CHEMBL353363 ZINC27868777 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50214937 N[C@H]1C=CCC[C@@H]1C(O)=O InChI=1S/C7H11NO2/c8-6-4-2-1-3-5(6)7(9)10/h2,4-6H,1,3,8H2,(H,9,10)/t5-,6-/m0/s1 CIXNUOPCFXQTTK-WDSKDSINSA-N 50118884 2-Amino-cyclohex-3-enecarboxylic acid::CHEMBL141917 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 125000 ChEMBL 10.1021/jm020134i 10.7270/Q2G1605T 12238932 Choi, S; Silverman, RB Northwestern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118884&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 10103265 104012139 CHEMBL141917 ZINC13491558 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50214938 N[C@@H]1C[C@H](CC=C1)C(O)=O InChI=1S/C7H11NO2/c8-6-3-1-2-5(4-6)7(9)10/h1,3,5-6H,2,4,8H2,(H,9,10)/t5-,6-/m0/s1 QOUDZMWPQSGONB-WDSKDSINSA-N 50118885 5-Amino-cyclohex-3-enecarboxylic acid::CHEMBL137992 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 100000 ChEMBL 10.1021/jm020134i 10.7270/Q2G1605T 12238932 Choi, S; Silverman, RB Northwestern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118885&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 10011990 104012140 CHEMBL137992 ZINC13491557 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50214939 NC(CCC(O)=O)C=C InChI=1S/C6H11NO2/c1-2-5(7)3-4-6(8)9/h2,5H,1,3-4,7H2,(H,8,9) PJDFLNIOAUIZSL-UHFFFAOYSA-N 50118886 4-Amino-hex-5-enoic acid::CHEMBL89598::US10189807, (S)-vigabatrin::VIGABATRIN 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 850000.0 ChEMBL 10.1021/jm020134i 10.7270/Q2G1605T 12238932 Choi, S; Silverman, RB Northwestern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118886 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118886&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 5665 104012141 63638 CHEMBL89598 DB01080 4821 C07500 ZINC03798750 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50214940 N[C@@H]1C=CCC[C@@H]1C(O)=O InChI=1S/C7H11NO2/c8-6-4-2-1-3-5(6)7(9)10/h2,4-6H,1,3,8H2,(H,9,10)/t5-,6+/m0/s1 CIXNUOPCFXQTTK-NTSWFWBYSA-N 50118887 2-Amino-cyclohex-3-enecarboxylic acid::CHEMBL138407 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 13000000 ChEMBL 10.1021/jm020134i 10.7270/Q2G1605T 12238932 Choi, S; Silverman, RB Northwestern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118887 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118887&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 7016465 104012142 CHEMBL138407 ZINC02526822 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50214941 N[C@H]1C[C@H](CC=C1)C(O)=O InChI=1S/C7H11NO2/c8-6-3-1-2-5(4-6)7(9)10/h1,3,5-6H,2,4,8H2,(H,9,10)/t5-,6+/m0/s1 QOUDZMWPQSGONB-NTSWFWBYSA-N 50118888 5-Amino-cyclohex-3-enecarboxylic acid::CHEMBL336887 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 2300000 ChEMBL 10.1021/jm020134i 10.7270/Q2G1605T 12238932 Choi, S; Silverman, RB Northwestern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118888&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 10419269 104012143 CHEMBL336887 ZINC27521839 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50278008 Oc1cc2oc(cc(=O)c2c(O)c1O)-c1ccccc1 InChI=1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H FXNFHKRTJBSTCS-UHFFFAOYSA-N 50009001 5,6,7-Trihydroxyflavone::5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one::Baicalein::Baicalein, 14::Baicalein, 8::CHEMBL8260::US10252984, Table 2.33 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 12800000 ChEMBL 10.1016/j.ejmech.2014.07.013 10.7270/Q2GH9KMN 25019478 Singh, M; Kaur, M; Silakari, O Punjabi University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009001 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009001&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 3WL 7XAX,6M2N,8A0Q,4X2A 5281605 103922066 2979 CHEMBL8260 5144 C10023 ZINC03871633 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50328389 CCC(=O)c1ccc(O)cc1 InChI=1S/C9H10O2/c1-2-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H3 RARSHUDCJQSEFJ-UHFFFAOYSA-N 50177402 1-(4-hydroxy-phenyl)-propan-1-one::1-(4-hydroxyphenyl)propan-1-one::4'-Hydroxypropiophenone::CHEMBL312311::Paroxypropione 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 176000 ChEMBL 10.1016/j.bmcl.2005.10.040 10.7270/Q29G5MCH 16290145 Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177402 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177402&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 6271 104062870 CHEMBL312311 C13342 ZINC00001890 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50328390 OC[C@H]1O[C@@H](Oc2ccc(CO)cc2)[C@H](O)[C@@H](O)[C@@H]1O InChI=1S/C13H18O7/c14-5-7-1-3-8(4-2-7)19-13-12(18)11(17)10(16)9(6-15)20-13/h1-4,9-18H,5-6H2/t9-,10-,11+,12-,13-/m1/s1 PUQSUZTXKPLAPR-UJPOAAIJSA-N 50177403 (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(4-(hydroxymethyl)phenoxy)-tetrahydro-2H-pyran-3,4,5-triol::CHEMBL274739 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens >1000000 ChEMBL 10.1016/j.bmcl.2005.10.040 10.7270/Q29G5MCH 16290145 Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177403 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177403&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 115067 104062871 CHEMBL274739 C03400 ZINC03881790 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50328396 Oc1ccc(CN=O)cc1 InChI=1S/C7H7NO2/c9-7-3-1-6(2-4-7)5-8-10/h1-4,9H,5H2 UCMJYLGFDFZTDU-UHFFFAOYSA-N 50177406 4-hydroxybenzaldehyde oxime::CHEMBL202611 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens >1000000 ChEMBL 10.1016/j.bmcl.2005.10.040 10.7270/Q29G5MCH 16290145 Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177406 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177406&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search OX5 2OOZ 54346225 104062874 CHEMBL202611 ZINC04578804 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50328398 OCc1ccc(O)cc1 InChI=1S/C7H8O2/c8-5-6-1-3-7(9)4-2-6/h1-4,8-9H,5H2 BVJSUAQZOZWCKN-UHFFFAOYSA-N 50177408 4-(hydroxymethyl)phenol::4-Hydroxybenzyl alcohol::4HBA::CHEMBL202132::parahydroxybenzyl alcohol 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens >1000000 ChEMBL 10.1016/j.bmcl.2005.10.040 10.7270/Q29G5MCH 16290145 Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177408 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177408&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 125 104062876 67410 CHEMBL202132 C17467 ZINC00388762 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50328399 CC(=O)c1ccc(O)cc1 InChI=1S/C8H8O2/c1-6(9)7-2-4-8(10)5-3-7/h2-5,10H,1H3 TXFPEBPIARQUIG-UHFFFAOYSA-N 50177409 (4-hydroxyphenyl)ethan-1-one::1-(4-hydroxyphenyl)ethanone::4'-hydroxyacetophenone::4-Acetylphenol::4-Hydroxyacetophenone::CHEMBL201083::Methyl p-hydroxyphenyl ketone::p-Hydroxyacetophenone::p-Hydroxyphenyl methyl ketone::para-Hydroxyacetophenone 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 188000 ChEMBL 10.1016/j.bmcl.2005.10.040 10.7270/Q29G5MCH 16290145 Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177409 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177409&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search AC6 7FKN,5CQ8,5PHN,2O48,2GQ8,5PB8 7469 104062877 28032 CHEMBL201083 C10700 ZINC00330136 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50328400 Oc1ccc(C=O)cc1[N+]([O-])=O InChI=1S/C7H5NO4/c9-4-5-1-2-7(10)6(3-5)8(11)12/h1-4,10H YTHJCZRFJGXPTL-UHFFFAOYSA-N 50177410 4-hydroxy-3-nitrobenzaldehyde::CHEMBL378361 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 15500 ChEMBL 10.1016/j.bmcl.2005.10.040 10.7270/Q29G5MCH 16290145 Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177410 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177410&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 18169 104062878 CHEMBL378361 ZINC00562702 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50328404 COc1ccc(C=O)cc1 InChI=1S/C8H8O2/c1-10-8-4-2-7(6-9)3-5-8/h2-6H,1H3 ZRSNZINYAWTAHE-UHFFFAOYSA-N 50139370 4-Methoxy-benzaldehyde::4-methoxybenzaldehyde::CHEMBL161598 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens >1000000 ChEMBL 10.1016/j.bmcl.2005.10.040 10.7270/Q29G5MCH 16290145 Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139370 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139370&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 31244 104029263 CHEMBL161598 C10761 ZINC00157146 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50328405 COc1cc(CN=O)ccc1O InChI=1S/C8H9NO3/c1-12-8-4-6(5-9-11)2-3-7(8)10/h2-4,10H,5H2,1H3 GLXIIOGHIFKSBY-UHFFFAOYSA-N 50177413 4-hydroxy-3-methoxybenzaldehyde oxime::CHEMBL202440 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens >1000000 ChEMBL 10.1016/j.bmcl.2005.10.040 10.7270/Q29G5MCH 16290145 Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177413 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177413&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 53845260 104062881 CHEMBL202440 ZINC18217828 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50328407 COc1cc(C=O)ccc1O InChI=1S/C8H8O3/c1-11-8-4-6(5-9)2-3-7(8)10/h2-5,10H,1H3 MWOOGOJBHIARFG-UHFFFAOYSA-N 50177405 3-methoxy-4-hydroxybenzaldehyde::4-hydroxy-3-methoxybenzaldehyde::4-hydroxy-m-anisaldehyde::CHEMBL13883::p-hydroxy-m-methoxybenzaldehyde::p-vanillin::vanillin 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 17100 ChEMBL 10.1016/j.bmcl.2005.10.040 10.7270/Q29G5MCH 16290145 Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177405 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177405&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search V55 2VSU,2VSS,5OMR,6XM9,7R0S,7R0U,7XWV,5J55,4RGS,6HOU,6HOP,6YCT,6YCK,6YCL,6YCM,5FXP 1183 104062873 18346 CHEMBL13883 6412 C00755 ZINC02567933 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50328410 OC(=O)c1ccc(O)cc1 InChI=1S/C7H6O3/c8-6-3-1-5(2-4-6)7(9)10/h1-4,8H,(H,9,10) FJKROLUGYXJWQN-UHFFFAOYSA-N 26194 4-Hydroxybenzoate, III::4-hydroxybenzoic acid::CHEMBL441343::p-Hydroxybenzoic acid::phenol derivative, 8 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens >1000000 ChEMBL 10.1016/j.bmcl.2005.10.040 10.7270/Q29G5MCH 16290145 Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26194 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26194&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search PHB 2BUW,2BUR,1G81,1BKW,6KCL,6KCM,6KCK,1IUW,1IUV,1IUX,1PXB,1PDH,3ZYB,1G1B,1CJ2,1Q4S,5D2A,4LKE,4LKD,4LKF,4OD5,1CC4,1PBE,1BF3,4EVS,4EVQ,4EY3,3TYB,1BGJ,1BGN,1DOB,1DOC,5IGA,2PHH,1PXA,7CUO,1K0I,4F06,3PCC,5I5P,1CJ3,7DQB,1TT8,6AL9,1JD3,1PXC,1CC6,1YKJ,3HGR,3HGS,1D7L,5RTJ,4E3G,1CJ4,3R3A,3R36,1FW9,7ON9,5W1E,5M21 135 56464631 30763 CHEMBL441343 DB04242 C00156 ZINC00332752 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50328412 Oc1ccc(cc1)C(=O)C=C InChI=1S/C9H8O2/c1-2-9(11)7-3-5-8(10)6-4-7/h2-6,10H,1H2 NKPPNPJUBLEKAD-UHFFFAOYSA-N 50177407 1-(4-hydroxyphenyl)prop-2-en-1-one::4-acryloylphenol::CHEMBL378577 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 5480 ChEMBL 10.1016/j.bmcl.2005.10.040 10.7270/Q29G5MCH 16290145 Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177407 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177407&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 16036927 104062875 CHEMBL378577 ZINC28567957 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50328415 Oc1ccc(C=O)cc1 InChI=1S/C7H6O2/c8-5-6-1-3-7(9)4-2-6/h1-5,9H RGHHSNMVTDWUBI-UHFFFAOYSA-N 50177411 4-formylphenol::4-hydroxybenzaldehyde::CHEMBL14193::p-formylphenol 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 16500 ChEMBL 10.1016/j.bmcl.2005.10.040 10.7270/Q29G5MCH 16290145 Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177411 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177411&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search HBA 1Z42,4TMC,7PHO,1OYB,4JQN,3ZOE,3ZOC,1EB9,2VQ5,7OFT,1K03,3ATZ,5V4P,4RNV,5DY3,2GQ9,3HGJ,5E4M,7ETI,4JIP,5K1K,6S31 126 104062879 17597 CHEMBL14193 DB03560 C00633 ZINC00156709 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50328416 NCc1ccc(O)cc1 InChI=1S/C7H9NO/c8-5-6-1-3-7(9)4-2-6/h1-4,9H,5,8H2 RQJDUEKERVZLLU-UHFFFAOYSA-N 50177412 4-(aminomethyl)phenol::4-hydroxybenzylamine::CHEMBL202519 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 15400 ChEMBL 10.1016/j.bmcl.2005.10.040 10.7270/Q29G5MCH 16290145 Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177412 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177412&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 97472 104062880 50336 CHEMBL202519 ZINC00153933 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50328417 Nc1ccc(cc1)C(O)=O InChI=1S/C7H7NO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,8H2,(H,9,10) ALYNCZNDIQEVRV-UHFFFAOYSA-N 50145829 4-Aminobenzoesaeure::4-aminobenzoic acid::CHEMBL542::PABA::p-Aminobenzoesaeure::p-aminobenzoic acid::para-aminobenzoic acid 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens >1000000 ChEMBL 10.1016/j.bmcl.2005.10.040 10.7270/Q29G5MCH 16290145 Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145829 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145829&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search PAB 1IUU,1IUT,1IUS,7S2K,8SCD,3Q2A,6DAY,1PBD,7R86,3TYZ,5Z79,2DZA,7PD5 978 104034518 30753 CHEMBL542 DB02362 C00568 ZINC00000920 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50328418 OC[C@H]1O[C@@H](Oc2ccc(C=O)cc2)[C@H](O)[C@H](O)[C@@H]1O InChI=1S/C13H16O7/c14-5-7-1-3-8(4-2-7)19-13-12(18)11(17)10(16)9(6-15)20-13/h1-5,9-13,15-18H,6H2/t9-,10-,11-,12-,13-/m1/s1 OLZAGZCCJJBKNZ-SYLRKERUSA-N 50177404 4-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-tetrahydro-2H-pyran-2-yloxy)benzaldehyde::4-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)benzaldehyde::CHEMBL201358::Helicide 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens >1000000 ChEMBL 10.1016/j.bmcl.2005.10.040 10.7270/Q29G5MCH 16290145 Tao, YH; Yuan, Z; Tang, XQ; Xu, HB; Yang, XL Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177404 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177404&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 12896796 104062872 CHEMBL201358 ZINC28568062 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50867578 NCc1cccc(c1)C(O)=O InChI=1S/C8H9NO2/c9-5-6-2-1-3-7(4-6)8(10)11/h1-4H,5,9H2,(H,10,11) GSWYUZQBLVUEPH-UHFFFAOYSA-N 50376750 CHEMBL541141 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens >5000000 ChEMBL 10.1016/j.bmcl.2007.10.060 10.7270/Q22J6CRF 17988865 Clift, MD; Silverman, RB Northwestern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376750 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376750&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 3AZ 3O3E,3O3D,3O3B,3O3A 506073 160855833 CHEMBL541141 ZINC04202416 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50867579 Nc1ccccc1C(O)=O InChI=1S/C7H7NO2/c8-6-4-2-1-3-5(6)7(9)10/h1-4H,8H2,(H,9,10) RWZYAGGXGHYGMB-UHFFFAOYSA-N 50376751 ANTHRANILIC ACID 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens >5000000 ChEMBL 10.1016/j.bmcl.2007.10.060 10.7270/Q22J6CRF 17988865 Clift, MD; Silverman, RB Northwestern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376751 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376751&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 6AB 227 160855834 30754 DB04166 C00108 ZINC00047985 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50867580 NCc1ccccc1CC(O)=O InChI=1S/C9H11NO2/c10-6-8-4-2-1-3-7(8)5-9(11)12/h1-4H,5-6,10H2,(H,11,12) VLOIVYPDUSVCLZ-UHFFFAOYSA-N 50376752 CHEMBL535644 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens >5000000 ChEMBL 10.1016/j.bmcl.2007.10.060 10.7270/Q22J6CRF 17988865 Clift, MD; Silverman, RB Northwestern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376752 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376752&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 1514158 160855835 CHEMBL535644 ZINC04202816 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50867581 NCc1ccccc1C(O)=O InChI=1S/C8H9NO2/c9-5-6-3-1-2-4-7(6)8(10)11/h1-4H,5,9H2,(H,10,11) CLTMYNWFSDZKKI-UHFFFAOYSA-N 50376753 CHEMBL535415 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens >5000000 ChEMBL 10.1016/j.bmcl.2007.10.060 10.7270/Q22J6CRF 17988865 Clift, MD; Silverman, RB Northwestern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376753 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376753&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 277942 160855836 CHEMBL535415 ZINC01715584 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50867582 Nc1cccc(CC(O)=O)c1 InChI=1S/C8H9NO2/c9-7-3-1-2-6(4-7)5-8(10)11/h1-4H,5,9H2,(H,10,11) XUSKZLBLGHBCLD-UHFFFAOYSA-N 50376754 CHEMBL535865 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens >5000000 ChEMBL 10.1016/j.bmcl.2007.10.060 10.7270/Q22J6CRF 17988865 Clift, MD; Silverman, RB Northwestern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376754&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 571807 160855837 CHEMBL535865 ZINC00154768 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50867583 Nc1cccc(c1)C(O)=O InChI=1S/C7H7NO2/c8-6-3-1-2-5(4-6)7(9)10/h1-4H,8H2,(H,9,10) XFDUHJPVQKIXHO-UHFFFAOYSA-N 50226518 3-Aminobenzoesaeure::3-aminobenzoic acid::CHEMBL307782::m-Aminobenzoesaeure 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens >5000000 ChEMBL 10.1016/j.bmcl.2007.10.060 10.7270/Q22J6CRF 17988865 Clift, MD; Silverman, RB Northwestern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50226518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50226518&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search GAB 1GBN,5CSV,3FQA,3GSB,3FHB,2PQF,5K3W,6SPU,6XU3 7419 104097156 42682 CHEMBL307782 DB02054 ZINC00388179 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50867584 NCc1cccc(CC(O)=O)c1 InChI=1S/C9H11NO2/c10-6-8-3-1-2-7(4-8)5-9(11)12/h1-4H,5-6,10H2,(H,11,12) OMILONVYAUZURK-UHFFFAOYSA-N 50376755 CHEMBL535643 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens >5000000 ChEMBL 10.1016/j.bmcl.2007.10.060 10.7270/Q22J6CRF 17988865 Clift, MD; Silverman, RB Northwestern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376755&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search V8N 8AQK,8AQB,8AQA,7OC2,7PFZ,7PGC 22247029 160855838 CHEMBL535643 ZINC29043818 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50977498 [NH3+]Cc1ccc(F)c([O-])c1F InChI=1S/C7H7F2NO/c8-5-2-1-4(3-10)6(9)7(5)11/h1-2,11H,3,10H2 ARLSXSJLCYMMDM-UHFFFAOYSA-N 50082127 3-(ammoniomethyl)-2,6-difluorobenzenolate::3-Aminomethyl-2,6-difluoro-phenol::CHEMBL321931 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 6300000 ChEMBL 10.1021/jm1013693 10.7270/Q24M95PH 21413808 Meanwell, NA Bristol-Myers Squibb Pharmaceutical Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082127 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082127&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 44335610 103981986 58001 CHEMBL321931 ZINC13556339 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50977499 NCc1cc(F)c(O)c(F)c1 InChI=1S/C7H7F2NO/c8-5-1-4(3-10)2-6(9)7(5)11/h1-2,11H,3,10H2 XIGBWMMDVPCKSD-UHFFFAOYSA-N 50073151 4-(ammoniomethyl)-2,6-difluorobenzenolate::4-Aminomethyl-2,6-difluoro-phenol::CHEMBL112496 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 11000000 ChEMBL 10.1021/jm1013693 10.7270/Q24M95PH 21413808 Meanwell, NA Bristol-Myers Squibb Pharmaceutical Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073151 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073151&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 10419448 103966619 CHEMBL112496 ZINC26832456 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 50977947 NC(CCC(O)=O)C=C InChI=1S/C6H11NO2/c1-2-5(7)3-4-6(8)9/h2,5H,1,3-4,7H2,(H,8,9) PJDFLNIOAUIZSL-UHFFFAOYSA-N 50118886 4-Amino-hex-5-enoic acid::CHEMBL89598::US10189807, (S)-vigabatrin::VIGABATRIN 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 3200000 ChEMBL 10.1021/jm201231w 10.7270/Q2QF8V1F 22128851 Pan, Y; Gerasimov, MR; Kvist, T; Wellendorph, P; Madsen, KK; Pera, E; Lee, H; Schousboe, A; Chebib, M; Brauner-Osborne, H; Craft, CM; Brodie, JD; Schiffer, WK; Dewey, SL; Miller, SR; Silverman, RB Northwestern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118886 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118886&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 5665 104012141 63638 CHEMBL89598 DB01080 4821 C07500 ZINC03798750 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 637068 N[C@@H]1CS[C@@H](C1)C(O)=O InChI=1S/C5H9NO2S/c6-3-1-4(5(7)8)9-2-3/h3-4H,1-2,6H2,(H,7,8)/t3-,4-/m0/s1 DHQBUVNDDNLKOA-IMJSIDKUSA-N 323799 (2S,4S)-4-Aminotetrahydrothiophene-2-carboxylic acid::US10189807, Compound 17 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 182000 US Patent 10.7270/Q2C82CDG aid1796742 US10189807 Silverman, RB; Le, HV; Hawker, DD Northwestern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=323799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=323799&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 96636364 384578873 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 637069 N[C@@H]1CS[C@H](C1)C(O)=O InChI=1S/C5H9NO2S/c6-3-1-4(5(7)8)9-2-3/h3-4H,1-2,6H2,(H,7,8)/t3-,4+/m0/s1 DHQBUVNDDNLKOA-IUYQGCFVSA-N 323800 (2R,4S)-4-Aminotetrahydrothiophene-2-carboxylic acid::US10189807, Compound 18::US10800753, Compound 18 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 2230000 US Patent 10.7270/Q2C82CDG aid1796742 US10189807 Silverman, RB; Le, HV; Hawker, DD Northwestern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=323800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=323800&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 96636366 384578874 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 637070 [NH3+][C@H]1C[C@H](C([O-])=O)S(=O)(=O)C1 InChI=1S/C5H9NO4S/c6-3-1-4(5(7)8)11(9,10)2-3/h3-4H,1-2,6H2,(H,7,8)/t3-,4+/m0/s1 XXXGOEMFPBKAPK-IUYQGCFVSA-N 323801 (4S)-4-Aminotetrahydrothiophene-2-carboxylic acid 1,1-dioxide::US10189807, Compound 19 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 3200000 US Patent 10.7270/Q2C82CDG aid1796742 US10189807 Silverman, RB; Le, HV; Hawker, DD Northwestern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=323801 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=323801&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 138403899 384578875 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 637071 [NH3+][C@H]1CS[C@H](C1)C([O-])=O InChI=1S/C5H9NO2S/c6-3-1-4(5(7)8)9-2-3/h3-4H,1-2,6H2,(H,7,8)/t3-,4-/m1/s1 DHQBUVNDDNLKOA-QWWZWVQMSA-N 323802 US10189807, Compound 20 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 3400000 US Patent 10.7270/Q2C82CDG aid1796742 US10189807 Silverman, RB; Le, HV; Hawker, DD Northwestern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=323802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=323802&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 138403901 384578876 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 637072 [NH3+][C@H]1CS[C@@H](C1)C([O-])=O InChI=1S/C5H9NO2S/c6-3-1-4(5(7)8)9-2-3/h3-4H,1-2,6H2,(H,7,8)/t3-,4+/m1/s1 DHQBUVNDDNLKOA-DMTCNVIQSA-N 323803 US10189807, Compound 21 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 3300000 US Patent 10.7270/Q2C82CDG aid1796742 US10189807 Silverman, RB; Le, HV; Hawker, DD Northwestern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=323803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=323803&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 138403902 384578877 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 637073 [NH3+][C@@H]1CC(C([O-])=O)S(=O)(=O)C1 InChI=1S/C5H9NO4S/c6-3-1-4(5(7)8)11(9,10)2-3/h3-4H,1-2,6H2,(H,7,8)/t3-,4?/m1/s1 XXXGOEMFPBKAPK-SYPWQXSBSA-N 323805 US10189807, Compound 22 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 7500000 US Patent 10.7270/Q2C82CDG aid1796742 US10189807 Silverman, RB; Le, HV; Hawker, DD Northwestern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=323805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=323805&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 138403903 384578879 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 637074 NC(CCC(O)=O)C=C InChI=1S/C6H11NO2/c1-2-5(7)3-4-6(8)9/h2,5H,1,3-4,7H2,(H,8,9) PJDFLNIOAUIZSL-UHFFFAOYSA-N 50118886 4-Amino-hex-5-enoic acid::CHEMBL89598::US10189807, (S)-vigabatrin::VIGABATRIN 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 3200000 US Patent 10.7270/Q2C82CDG aid1796742 US10189807 Silverman, RB; Le, HV; Hawker, DD Northwestern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118886 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118886&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 5665 104012141 63638 CHEMBL89598 DB01080 4821 C07500 ZINC03798750 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 51268235 [NH3+]Cc1ccc(F)c([O-])c1F InChI=1S/C7H7F2NO/c8-5-2-1-4(3-10)6(9)7(5)11/h1-2,11H,3,10H2 ARLSXSJLCYMMDM-UHFFFAOYSA-N 50082127 3-(ammoniomethyl)-2,6-difluorobenzenolate::3-Aminomethyl-2,6-difluoro-phenol::CHEMBL321931 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 6300000 ChEMBL 10.1021/acs.jmedchem.7b01788 10.7270/Q232008T 29400967 Meanwell, NA Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082127 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082127&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 44335610 103981986 58001 CHEMBL321931 ZINC13556339 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 51268300 NCc1cc(F)c(O)c(F)c1 InChI=1S/C7H7F2NO/c8-5-1-4(3-10)2-6(9)7(5)11/h1-2,11H,3,10H2 XIGBWMMDVPCKSD-UHFFFAOYSA-N 50073151 4-(ammoniomethyl)-2,6-difluorobenzenolate::4-Aminomethyl-2,6-difluoro-phenol::CHEMBL112496 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 11000000 ChEMBL 10.1021/acs.jmedchem.7b01788 10.7270/Q232008T 29400967 Meanwell, NA Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073151 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073151&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 10419448 103966619 CHEMBL112496 ZINC26832456 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 963794 COC(=O)[C@@H]1C[C@H](N)CS1 InChI=1S/C6H11NO2S/c1-9-6(8)5-2-4(7)3-10-5/h4-5H,2-3,7H2,1H3/t4-,5-/m0/s1 YVWUCJPPXTUFKU-WHFBIAKZSA-N 466532 US10800753, Compound 17 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 182000 US Patent 10.7270/Q2ZC85ZR aid1804883 US10800753 Silverman, RB; Le, HV; Hawker, DD Northwestern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=466532 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=466532&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 96633981 441576238 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 963795 N[C@@H]1CS[C@H](C1)C(O)=O InChI=1S/C5H9NO2S/c6-3-1-4(5(7)8)9-2-3/h3-4H,1-2,6H2,(H,7,8)/t3-,4+/m0/s1 DHQBUVNDDNLKOA-IUYQGCFVSA-N 323800 (2R,4S)-4-Aminotetrahydrothiophene-2-carboxylic acid::US10189807, Compound 18::US10800753, Compound 18 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 2230000 US Patent 10.7270/Q2ZC85ZR aid1804883 US10800753 Silverman, RB; Le, HV; Hawker, DD Northwestern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=323800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=323800&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 96636366 384578874 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 963796 N[C@H]1CC(C(O)=O)S(=O)(=O)C1 InChI=1S/C5H9NO4S/c6-3-1-4(5(7)8)11(9,10)2-3/h3-4H,1-2,6H2,(H,7,8)/t3-,4?/m0/s1 XXXGOEMFPBKAPK-WUCPZUCCSA-N 466536 US10800753, Compound 19 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 3200000 US Patent 10.7270/Q2ZC85ZR aid1804883 US10800753 Silverman, RB; Le, HV; Hawker, DD Northwestern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=466536 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=466536&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 122403361 441576242 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 963797 N[C@H]1CS[C@H](C1)C(O)=O InChI=1S/C5H9NO2S/c6-3-1-4(5(7)8)9-2-3/h3-4H,1-2,6H2,(H,7,8)/t3-,4-/m1/s1 DHQBUVNDDNLKOA-QWWZWVQMSA-N 466537 US10800753, Compound 20 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 3400000 US Patent 10.7270/Q2ZC85ZR aid1804883 US10800753 Silverman, RB; Le, HV; Hawker, DD Northwestern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=466537 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=466537&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 96636367 441576243 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 963798 N[C@H]1CS[C@@H](C1)C(O)=O InChI=1S/C5H9NO2S/c6-3-1-4(5(7)8)9-2-3/h3-4H,1-2,6H2,(H,7,8)/t3-,4+/m1/s1 DHQBUVNDDNLKOA-DMTCNVIQSA-N 466538 US10800753, Compound 21 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 3300000 US Patent 10.7270/Q2ZC85ZR aid1804883 US10800753 Silverman, RB; Le, HV; Hawker, DD Northwestern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=466538 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=466538&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 96636365 441576244 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 963799 N[C@@H]1CC(C(O)=O)S(=O)(=O)C1 InChI=1S/C5H9NO4S/c6-3-1-4(5(7)8)11(9,10)2-3/h3-4H,1-2,6H2,(H,7,8)/t3-,4?/m1/s1 XXXGOEMFPBKAPK-SYPWQXSBSA-N 466539 US10800753, Compound 22 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 7500000 US Patent 10.7270/Q2ZC85ZR aid1804883 US10800753 Silverman, RB; Le, HV; Hawker, DD Northwestern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=466539 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=466539&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 122403365 441576245 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 963800 N[C@H](CCC(O)=O)C=C InChI=1S/C6H11NO2/c1-2-5(7)3-4-6(8)9/h2,5H,1,3-4,7H2,(H,8,9)/t5-/m0/s1 PJDFLNIOAUIZSL-YFKPBYRVSA-N 50357219 CHEMBL1361446::US10800753, Compound (S)-vigabatrin::VIGABATRIN 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 3200000 US Patent 10.7270/Q2ZC85ZR aid1804883 US10800753 Silverman, RB; Le, HV; Hawker, DD Northwestern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50357219 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50357219&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 157018 136961243 63638 CHEMBL1361446 C07500 ZINC00403618 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 51573213 N[C@H]1CC(CC1=C(F)F)C(O)=O InChI=1S/C7H9F2NO2/c8-6(9)4-1-3(7(11)12)2-5(4)10/h3,5H,1-2,10H2,(H,11,12)/t3?,5-/m0/s1 CBSRETZPFOBWNG-PVPKANODSA-N 50632820 CHEMBL5404015 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 31000 ChEMBL 10.1021/acs.jmedchem.2c01975 10.7270/Q2SQ94V8 37012671 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632820 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632820&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 51573214 N[C@H]1C=C(CC1=C(F)F)C(O)=O InChI=1S/C7H7F2NO2/c8-6(9)4-1-3(7(11)12)2-5(4)10/h2,5H,1,10H2,(H,11,12)/t5-/m0/s1 FBLNZOCTNRXJQD-YFKPBYRVSA-N 50561618 CHEMBL4746439 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 9690 ChEMBL 10.1021/acs.jmedchem.2c01975 10.7270/Q2SQ94V8 37012671 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50561618 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50561618&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 126764043 461832010 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 51573215 COc1ccc(cc1)N1C(CC(=NC1=S)c1ccccc1)c1ccccc1 InChI=1S/C23H20N2OS/c1-26-20-14-12-19(13-15-20)25-22(18-10-6-3-7-11-18)16-21(24-23(25)27)17-8-4-2-5-9-17/h2-15,22H,16H2,1H3 RDNVAXRZOSLCCO-UHFFFAOYSA-N 50632821 CHEMBL4750359 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 18420 ChEMBL 10.1021/acs.jmedchem.2c01975 10.7270/Q2SQ94V8 37012671 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632821 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632821&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 51573216 Oc1ccc(cc1)C1=NC(=S)N(C(C1)c1ccccc1)c1ccccc1[N+]([O-])=O InChI=1S/C22H17N3O3S/c26-17-12-10-15(11-13-17)18-14-21(16-6-2-1-3-7-16)24(22(29)23-18)19-8-4-5-9-20(19)25(27)28/h1-13,21,26H,14H2 MKKDREKCTHQQNM-UHFFFAOYSA-N 50632822 CHEMBL5408239 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 19230 ChEMBL 10.1021/acs.jmedchem.2c01975 10.7270/Q2SQ94V8 37012671 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632822&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800 51573217 Cc1ccc(NC(=S)N2C(CC(=NC2=S)c2ccccc2)c2ccc(O)cc2)cc1 InChI=1S/C24H21N3OS2/c1-16-7-11-19(12-8-16)25-23(29)27-22(18-9-13-20(28)14-10-18)15-21(26-24(27)30)17-5-3-2-4-6-17/h2-14,22,28H,15H2,1H3,(H,25,29) YMAFDZYZUPMMAI-UHFFFAOYSA-N 50632823 CHEMBL4740703 4-aminobutyrate aminotransferase, mitochondrial Homo sapiens 12230 ChEMBL 10.1021/acs.jmedchem.2c01975 10.7270/Q2SQ94V8 37012671 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50632823 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50000150&target=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50632823&enzyme=4-aminobutyrate+aminotransferase%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 1 MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK 4-aminobutyrate aminotransferase, mitochondrial GABT_HUMAN P80404 A8K386 Q16260 Q8N5W2 Q96BG2 Q99800