BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 51034064 COc1cccc(c1)[C@H](N1C[C@@H](C)N(Cc2ccccc2)C[C@@H]1C)c1ccc2CCN(CC(O)=O)Cc2c1 InChI=1S/C32H39N3O3/c1-23-19-35(24(2)18-34(23)20-25-8-5-4-6-9-25)32(27-10-7-11-30(17-27)38-3)28-13-12-26-14-15-33(22-31(36)37)21-29(26)16-28/h4-13,16-17,23-24,32H,14-15,18-22H2,1-3H3,(H,36,37)/t23-,24+,32+/m1/s1 VZHGAQSLJSYVIX-FXZPAHAQSA-N 50422792 CHEMBL202478 Mu-type opioid receptor Cavia cutleri 5012 ChEMBL 10.1016/j.bmcl.2005.10.102 10.7270/Q2930VG2 16290934 Middleton, DS; Maw, GN; Challenger, C; Jessiman, A; Johnson, PS; Million, WA; Nichols, CL; Price, JA; Trevethick, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422792&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11555338 164151667 CHEMBL202478 ZINC28568852 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51034065 C[C@@H]1CN([C@H](c2ccc3CN(Cc3c2)C(=O)c2ccccc2C(O)=O)c2cccc(O)c2)[C@@H](C)CN1Cc1ccccc1 InChI=1S/C36H37N3O4/c1-24-20-39(25(2)19-37(24)21-26-9-4-3-5-10-26)34(27-11-8-12-31(40)18-27)28-15-16-29-22-38(23-30(29)17-28)35(41)32-13-6-7-14-33(32)36(42)43/h3-18,24-25,34,40H,19-23H2,1-2H3,(H,42,43)/t24-,25+,34+/m1/s1 WHLHPAOIEWMCRA-ISVMRZDUSA-N 50422793 CHEMBL203903 Mu-type opioid receptor Cavia cutleri 50 ChEMBL 10.1016/j.bmcl.2005.10.102 10.7270/Q2930VG2 16290934 Middleton, DS; Maw, GN; Challenger, C; Jessiman, A; Johnson, PS; Million, WA; Nichols, CL; Price, JA; Trevethick, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422793&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44407732 164151668 CHEMBL203903 ZINC28570400 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51034066 C[C@@H]1CN([C@@H](c2cccc(O)c2)c2ccc3CCN(Cc3c2)C(=O)CC(O)=O)[C@@H](C)CN1Cc1ccccc1 InChI=1S/C32H37N3O4/c1-22-19-35(23(2)18-34(22)20-24-7-4-3-5-8-24)32(26-9-6-10-29(36)16-26)27-12-11-25-13-14-33(21-28(25)15-27)30(37)17-31(38)39/h3-12,15-16,22-23,32,36H,13-14,17-21H2,1-2H3,(H,38,39)/t22-,23+,32+/m1/s1 LNHGYHTWTCRAMU-MODXFSQWSA-N 50422795 CHEMBL202585 Mu-type opioid receptor Cavia cutleri 200 ChEMBL 10.1016/j.bmcl.2005.10.102 10.7270/Q2930VG2 16290934 Middleton, DS; Maw, GN; Challenger, C; Jessiman, A; Johnson, PS; Million, WA; Nichols, CL; Price, JA; Trevethick, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422795 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422795&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44407564 164151670 CHEMBL202585 C01656 ZINC28568771 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51034069 C[C@@H]1CN([C@H](c2ccc3CN(CC(O)=O)Cc3c2)c2cccc(O)c2)[C@@H](C)CN1Cc1ccccc1 InChI=1S/C30H35N3O3/c1-21-16-33(22(2)15-32(21)17-23-7-4-3-5-8-23)30(24-9-6-10-28(34)14-24)25-11-12-26-18-31(20-29(35)36)19-27(26)13-25/h3-14,21-22,30,34H,15-20H2,1-2H3,(H,35,36)/t21-,22+,30+/m1/s1 GRRGEIIPSQHREY-DGIFUFQNSA-N 50422798 CHEMBL201678 Mu-type opioid receptor Cavia cutleri 126 ChEMBL 10.1016/j.bmcl.2005.10.102 10.7270/Q2930VG2 16290934 Middleton, DS; Maw, GN; Challenger, C; Jessiman, A; Johnson, PS; Million, WA; Nichols, CL; Price, JA; Trevethick, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422798&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44407550 164151673 CHEMBL201678 ZINC28568834 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51034079 C[C@@H]1CN([C@H](c2ccc3CN(CCC(O)=O)Cc3c2)c2cccc(O)c2)[C@@H](C)CN1Cc1ccccc1 InChI=1S/C31H37N3O3/c1-22-18-34(23(2)17-33(22)19-24-7-4-3-5-8-24)31(25-9-6-10-29(35)16-25)26-11-12-27-20-32(14-13-30(36)37)21-28(27)15-26/h3-12,15-16,22-23,31,35H,13-14,17-21H2,1-2H3,(H,36,37)/t22-,23+,31+/m1/s1 LWDBFMLELKVTQP-UDKTZTBJSA-N 50422796 CHEMBL201205 Mu-type opioid receptor Cavia cutleri 631 ChEMBL 10.1016/j.bmcl.2005.10.102 10.7270/Q2930VG2 16290934 Middleton, DS; Maw, GN; Challenger, C; Jessiman, A; Johnson, PS; Million, WA; Nichols, CL; Price, JA; Trevethick, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422796&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44407699 164151671 CHEMBL201205 ZINC28569086 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51034088 COc1cccc(c1)[C@H](N1C[C@@H](C)N(Cc2ccccc2)C[C@@H]1C)c1ccc2CN(Cc2c1)C(=O)c1ccc(cc1)C(O)=O InChI=1S/C37H39N3O4/c1-25-21-40(26(2)20-38(25)22-27-8-5-4-6-9-27)35(30-10-7-11-34(19-30)44-3)31-16-17-32-23-39(24-33(32)18-31)36(41)28-12-14-29(15-13-28)37(42)43/h4-19,25-26,35H,20-24H2,1-3H3,(H,42,43)/t25-,26+,35+/m1/s1 DHZNWMDZVMDMAC-AWYDNWMNSA-N 50422810 CHEMBL381534 Mu-type opioid receptor Cavia cutleri 3162 ChEMBL 10.1016/j.bmcl.2005.10.102 10.7270/Q2930VG2 16290934 Middleton, DS; Maw, GN; Challenger, C; Jessiman, A; Johnson, PS; Million, WA; Nichols, CL; Price, JA; Trevethick, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422810 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422810&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44407877 164151685 CHEMBL381534 ZINC28570015 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51034090 C[C@@H]1CN([C@H](c2ccc3CN(Cc3c2)C(=O)c2cccc(c2)C(O)=O)c2cccc(O)c2)[C@@H](C)CN1Cc1ccccc1 InChI=1S/C36H37N3O4/c1-24-20-39(25(2)19-37(24)21-26-8-4-3-5-9-26)34(27-10-7-13-33(40)18-27)28-14-15-31-22-38(23-32(31)16-28)35(41)29-11-6-12-30(17-29)36(42)43/h3-18,24-25,34,40H,19-23H2,1-2H3,(H,42,43)/t24-,25+,34+/m1/s1 FZFSEHRCJNQRIE-ISVMRZDUSA-N 50422801 CHEMBL382761 Mu-type opioid receptor Cavia cutleri 100 ChEMBL 10.1016/j.bmcl.2005.10.102 10.7270/Q2930VG2 16290934 Middleton, DS; Maw, GN; Challenger, C; Jessiman, A; Johnson, PS; Million, WA; Nichols, CL; Price, JA; Trevethick, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422801 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422801&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44407876 164151676 CHEMBL382761 ZINC28570206 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51034097 C[C@@H]1CN([C@@H](c2cccc(O)c2)c2ccc3CCN(Cc3c2)C(=O)C(O)=O)[C@@H](C)CN1Cc1ccccc1 InChI=1S/C31H35N3O4/c1-21-18-34(22(2)17-33(21)19-23-7-4-3-5-8-23)29(25-9-6-10-28(35)16-25)26-12-11-24-13-14-32(20-27(24)15-26)30(36)31(37)38/h3-12,15-16,21-22,29,35H,13-14,17-20H2,1-2H3,(H,37,38)/t21-,22+,29+/m1/s1 XUYXSBCTKCHFMO-BXOOBUKZSA-N 50422811 CHEMBL204716 Mu-type opioid receptor Cavia cutleri 200 ChEMBL 10.1016/j.bmcl.2005.10.102 10.7270/Q2930VG2 16290934 Middleton, DS; Maw, GN; Challenger, C; Jessiman, A; Johnson, PS; Million, WA; Nichols, CL; Price, JA; Trevethick, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422811 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422811&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44407790 164151686 CHEMBL204716 ZINC28570512 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51034098 C[C@@H]1CN([C@@H](c2cccc(O)c2)c2ccc3CCN(CCC(O)=O)Cc3c2)[C@@H](C)CN1Cc1ccccc1 InChI=1S/C32H39N3O3/c1-23-20-35(24(2)19-34(23)21-25-7-4-3-5-8-25)32(27-9-6-10-30(36)18-27)28-12-11-26-13-15-33(16-14-31(37)38)22-29(26)17-28/h3-12,17-18,23-24,32,36H,13-16,19-22H2,1-2H3,(H,37,38)/t23-,24+,32+/m1/s1 LSPFSEDULXVHTC-FXZPAHAQSA-N 50422791 CHEMBL204480 Mu-type opioid receptor Cavia cutleri 1000 ChEMBL 10.1016/j.bmcl.2005.10.102 10.7270/Q2930VG2 16290934 Middleton, DS; Maw, GN; Challenger, C; Jessiman, A; Johnson, PS; Million, WA; Nichols, CL; Price, JA; Trevethick, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422791&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44407736 164151666 CHEMBL204480 ZINC28570257 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51034099 C[C@@H]1CN([C@@H](c2cccc(O)c2)c2ccc3CCN(CC(O)=O)Cc3c2)[C@@H](C)CN1Cc1ccccc1 InChI=1S/C31H37N3O3/c1-22-18-34(23(2)17-33(22)19-24-7-4-3-5-8-24)31(26-9-6-10-29(35)16-26)27-12-11-25-13-14-32(21-30(36)37)20-28(25)15-27/h3-12,15-16,22-23,31,35H,13-14,17-21H2,1-2H3,(H,36,37)/t22-,23+,31+/m1/s1 RADOBVBWYWWWKV-UDKTZTBJSA-N 50422804 CHEMBL202578 Mu-type opioid receptor Cavia cutleri 316 ChEMBL 10.1016/j.bmcl.2005.10.102 10.7270/Q2930VG2 16290934 Middleton, DS; Maw, GN; Challenger, C; Jessiman, A; Johnson, PS; Million, WA; Nichols, CL; Price, JA; Trevethick, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422804 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422804&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44407697 164151679 CHEMBL202578 ZINC28568906 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51056271 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CC[C@@H](C1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=C)C(N)=O)c1ccco1 InChI=1S/C33H36N6O6/c1-19(30(35)41)29(28-7-4-14-45-28)38-32(43)27(16-22-17-36-26-6-3-2-5-24(22)26)37-31(42)21-12-13-39(18-21)33(44)25(34)15-20-8-10-23(40)11-9-20/h2-11,14,17,21,25,27,29,36,40H,1,12-13,15-16,18,34H2,(H2,35,41)(H,37,42)(H,38,43)/t21-,25-,27-,29+/m0/s1 QYOGKEMLQNWNLK-AWIVKJGVSA-N 50430804 CHEMBL2334769 Mu-type opioid receptor Cavia cutleri 8.1 ChEMBL 10.1021/jm400195y 10.7270/Q2KS6SW8 23477419 Liu, X; Wang, Y; Xing, Y; Yu, J; Ji, H; Kai, M; Wang, Z; Wang, D; Zhang, Y; Zhao, D; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50430804 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50430804&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71605421 164159679 CHEMBL2334769 ZINC95588274 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51056274 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CC[C@@H](C1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=C)C(N)=O)c1ccccc1 InChI=1S/C35H38N6O5/c1-21(32(37)43)31(23-7-3-2-4-8-23)40-34(45)30(18-25-19-38-29-10-6-5-9-27(25)29)39-33(44)24-15-16-41(20-24)35(46)28(36)17-22-11-13-26(42)14-12-22/h2-14,19,24,28,30-31,38,42H,1,15-18,20,36H2,(H2,37,43)(H,39,44)(H,40,45)/t24-,28-,30-,31+/m0/s1 AGAQXKAFDAOXKW-GLWIQRGKSA-N 50430805 CHEMBL2334768 Mu-type opioid receptor Cavia cutleri 3.2 ChEMBL 10.1021/jm400195y 10.7270/Q2KS6SW8 23477419 Liu, X; Wang, Y; Xing, Y; Yu, J; Ji, H; Kai, M; Wang, Z; Wang, D; Zhang, Y; Zhao, D; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50430805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50430805&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71605420 164159680 CHEMBL2334768 ZINC95590117 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51056278 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CC[C@H](C1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=C)C(N)=O)c1ccccc1 InChI=1S/C35H38N6O5/c1-21(32(37)43)31(23-7-3-2-4-8-23)40-34(45)30(18-25-19-38-29-10-6-5-9-27(25)29)39-33(44)24-15-16-41(20-24)35(46)28(36)17-22-11-13-26(42)14-12-22/h2-14,19,24,28,30-31,38,42H,1,15-18,20,36H2,(H2,37,43)(H,39,44)(H,40,45)/t24-,28+,30+,31-/m1/s1 AGAQXKAFDAOXKW-FSYRHIKOSA-N 50430807 CHEMBL2334770 Mu-type opioid receptor Cavia cutleri 1.8 ChEMBL 10.1021/jm400195y 10.7270/Q2KS6SW8 23477419 Liu, X; Wang, Y; Xing, Y; Yu, J; Ji, H; Kai, M; Wang, Z; Wang, D; Zhang, Y; Zhao, D; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50430807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50430807&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71605418 164159682 CHEMBL2334770 ZINC95591457 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51056279 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CC[C@H](C1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=C)C(N)=O)c1ccco1 InChI=1S/C33H36N6O6/c1-19(30(35)41)29(28-7-4-14-45-28)38-32(43)27(16-22-17-36-26-6-3-2-5-24(22)26)37-31(42)21-12-13-39(18-21)33(44)25(34)15-20-8-10-23(40)11-9-20/h2-11,14,17,21,25,27,29,36,40H,1,12-13,15-16,18,34H2,(H2,35,41)(H,37,42)(H,38,43)/t21-,25+,27+,29-/m1/s1 QYOGKEMLQNWNLK-JNAYRKKUSA-N 50430806 CHEMBL2334771 Mu-type opioid receptor Cavia cutleri 1.7 ChEMBL 10.1021/jm400195y 10.7270/Q2KS6SW8 23477419 Liu, X; Wang, Y; Xing, Y; Yu, J; Ji, H; Kai, M; Wang, Z; Wang, D; Zhang, Y; Zhao, D; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50430806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50430806&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71605419 164159681 CHEMBL2334771 ZINC95588845 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51056282 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CC[C@@H](C1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=C)C(N)=O)c1ccco1 InChI=1S/C35H40N6O6/c1-19-13-24(42)14-20(2)26(19)16-27(36)35(46)41-11-10-22(18-41)33(44)39-29(15-23-17-38-28-8-5-4-7-25(23)28)34(45)40-31(21(3)32(37)43)30-9-6-12-47-30/h4-9,12-14,17,22,27,29,31,38,42H,3,10-11,15-16,18,36H2,1-2H3,(H2,37,43)(H,39,44)(H,40,45)/t22-,27-,29-,31+/m0/s1 RIAOSVMITNWHAH-HFASDWQVSA-N 50430802 CHEMBL2334775 Mu-type opioid receptor Cavia cutleri 0.834000 ChEMBL 10.1021/jm400195y 10.7270/Q2KS6SW8 23477419 Liu, X; Wang, Y; Xing, Y; Yu, J; Ji, H; Kai, M; Wang, Z; Wang, D; Zhang, Y; Zhao, D; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50430802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50430802&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71605756 164159677 CHEMBL2334775 ZINC95592056 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51056283 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=C)C(O)=O)c1ccco1 InChI=1S/C35H39N5O7/c1-19-14-23(41)15-20(2)25(19)17-26(36)34(44)40-12-6-10-29(40)33(43)38-28(16-22-18-37-27-9-5-4-8-24(22)27)32(42)39-31(21(3)35(45)46)30-11-7-13-47-30/h4-5,7-9,11,13-15,18,26,28-29,31,37,41H,3,6,10,12,16-17,36H2,1-2H3,(H,38,43)(H,39,42)(H,45,46)/t26-,28-,29-,31+/m0/s1 QBPGLGPDPFXICV-YQOCYVMFSA-N 50430800 CHEMBL2334773 Mu-type opioid receptor Cavia cutleri 0.767000 ChEMBL 10.1021/jm400195y 10.7270/Q2KS6SW8 23477419 Liu, X; Wang, Y; Xing, Y; Yu, J; Ji, H; Kai, M; Wang, Z; Wang, D; Zhang, Y; Zhao, D; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50430800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50430800&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71719454 164159675 CHEMBL2334773 ZINC95592077 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51056289 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CC[C@@H](C1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=C)C(N)=O)c1ccccc1 InChI=1S/C37H42N6O5/c1-21-15-27(44)16-22(2)29(21)18-30(38)37(48)43-14-13-25(20-43)35(46)41-32(17-26-19-40-31-12-8-7-11-28(26)31)36(47)42-33(23(3)34(39)45)24-9-5-4-6-10-24/h4-12,15-16,19,25,30,32-33,40,44H,3,13-14,17-18,20,38H2,1-2H3,(H2,39,45)(H,41,46)(H,42,47)/t25-,30-,32-,33+/m0/s1 WPSMFHOVBQABMZ-RJILNQQKSA-N 50430803 CHEMBL2334774 Mu-type opioid receptor Cavia cutleri 0.539000 ChEMBL 10.1021/jm400195y 10.7270/Q2KS6SW8 23477419 Liu, X; Wang, Y; Xing, Y; Yu, J; Ji, H; Kai, M; Wang, Z; Wang, D; Zhang, Y; Zhao, D; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50430803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50430803&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71605755 164159678 CHEMBL2334774 ZINC95590609 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51056291 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=C)C(O)=O)c1ccccc1 InChI=1S/C37H41N5O6/c1-21-16-26(43)17-22(2)28(21)19-29(38)36(46)42-15-9-14-32(42)35(45)40-31(18-25-20-39-30-13-8-7-12-27(25)30)34(44)41-33(23(3)37(47)48)24-10-5-4-6-11-24/h4-8,10-13,16-17,20,29,31-33,39,43H,3,9,14-15,18-19,38H2,1-2H3,(H,40,45)(H,41,44)(H,47,48)/t29-,31-,32-,33+/m0/s1 VMGFMOIZZDBILY-DMBLRCPMSA-N 50430799 CHEMBL2334772 Mu-type opioid receptor Cavia cutleri 0.467000 ChEMBL 10.1021/jm400195y 10.7270/Q2KS6SW8 23477419 Liu, X; Wang, Y; Xing, Y; Yu, J; Ji, H; Kai, M; Wang, Z; Wang, D; Zhang, Y; Zhao, D; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50430799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50430799&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71720682 164159674 CHEMBL2334772 ZINC95591029 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51056294 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CC[C@H](C1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=C)C(N)=O)c1ccccc1 InChI=1S/C37H42N6O5/c1-21-15-27(44)16-22(2)29(21)18-30(38)37(48)43-14-13-25(20-43)35(46)41-32(17-26-19-40-31-12-8-7-11-28(26)31)36(47)42-33(23(3)34(39)45)24-9-5-4-6-10-24/h4-12,15-16,19,25,30,32-33,40,44H,3,13-14,17-18,20,38H2,1-2H3,(H2,39,45)(H,41,46)(H,42,47)/t25-,30+,32+,33-/m1/s1 WPSMFHOVBQABMZ-VWKWMHJASA-N 50430801 CHEMBL2334776 Mu-type opioid receptor Cavia cutleri 0.226000 ChEMBL 10.1021/jm400195y 10.7270/Q2KS6SW8 23477419 Liu, X; Wang, Y; Xing, Y; Yu, J; Ji, H; Kai, M; Wang, Z; Wang, D; Zhang, Y; Zhao, D; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50430801 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50430801&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71605588 164159676 CHEMBL2334776 ZINC95590014 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51056295 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CC[C@H](C1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=C)C(N)=O)c1ccco1 InChI=1S/C35H40N6O6/c1-19-13-24(42)14-20(2)26(19)16-27(36)35(46)41-11-10-22(18-41)33(44)39-29(15-23-17-38-28-8-5-4-7-25(23)28)34(45)40-31(21(3)32(37)43)30-9-6-12-47-30/h4-9,12-14,17,22,27,29,31,38,42H,3,10-11,15-16,18,36H2,1-2H3,(H2,37,43)(H,39,44)(H,40,45)/t22-,27+,29+,31-/m1/s1 RIAOSVMITNWHAH-XDERILFOSA-N 50430798 CHEMBL2335120 Mu-type opioid receptor Cavia cutleri 0.167000 ChEMBL 10.1021/jm400195y 10.7270/Q2KS6SW8 23477419 Liu, X; Wang, Y; Xing, Y; Yu, J; Ji, H; Kai, M; Wang, Z; Wang, D; Zhang, Y; Zhao, D; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50430798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50430798&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71605589 164159673 CHEMBL2335120 ZINC95589979 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 158994 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(O)=O InChI=1S/C154H248N42O44S/c1-17-82(10)123(150(235)191-121(80(6)7)148(233)181-98(43-28-33-60-159)133(218)185-108(69-115(163)205)138(223)170-83(11)127(212)182-107(68-91-71-165-77-169-91)143(228)177-95(40-25-30-57-156)131(216)174-94(39-24-29-56-155)130(215)168-74-119(209)172-102(154(239)240)50-53-114(162)204)192-128(213)84(12)171-139(224)109(70-116(164)206)184-132(217)96(41-26-31-58-157)176-142(227)106(67-89-37-22-19-23-38-89)183-140(225)103(63-78(2)3)187-151(236)125(86(14)200)194-149(234)122(81(8)9)190-144(229)104(64-79(4)5)186-147(232)112-44-34-61-196(112)153(238)126(87(15)201)195-136(221)99(49-52-113(161)203)178-145(230)110(75-197)188-134(219)97(42-27-32-59-158)175-135(220)100(51-54-120(210)211)179-146(231)111(76-198)189-152(237)124(85(13)199)193-137(222)101(55-62-241-16)180-141(226)105(66-88-35-20-18-21-36-88)173-118(208)73-166-117(207)72-167-129(214)93(160)65-90-45-47-92(202)48-46-90/h18-23,35-38,45-48,71,77-87,93-112,121-126,197-202H,17,24-34,39-44,49-70,72-76,155-160H2,1-16H3,(H2,161,203)(H2,162,204)(H2,163,205)(H2,164,206)(H,165,169)(H,166,207)(H,167,214)(H,168,215)(H,170,223)(H,171,224)(H,172,209)(H,173,208)(H,174,216)(H,175,220)(H,176,227)(H,177,228)(H,178,230)(H,179,231)(H,180,226)(H,181,233)(H,182,212)(H,183,225)(H,184,217)(H,185,218)(H,186,232)(H,187,236)(H,188,219)(H,189,237)(H,190,229)(H,191,235)(H,192,213)(H,193,222)(H,194,234)(H,195,221)(H,210,211)(H,239,240)/t82-,83-,84-,85+,86+,87+,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,121-,122-,123-,124-,125-,126-/m0/s1 WAGZGJMGRRVHFE-XTLYPBBASA-N 81934 Beta-Endorphin Mu-type opioid receptor Cavia cutleri 37.1 PDSP Ki 10.7270/Q2NC5ZPR 6248635 Leslie, FM; Chavkin, C; Cox, BM Stanford University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81934 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81934&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16144003 131342508 C02716 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 158995 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C)[C@@H](Cc1ccccc1)C(=O)NCCO InChI=1S/C26H35N5O6/c1-17(30-25(36)21(27)14-19-8-10-20(33)11-9-19)24(35)29-16-23(34)31(2)22(26(37)28-12-13-32)15-18-6-4-3-5-7-18/h3-11,17,21-22,32-33H,12-16,27H2,1-2H3,(H,28,37)(H,29,35)(H,30,36)/t17-,21+,22+/m1/s1 HPZJMUBDEAMBFI-WTNAPCKOSA-N 21015 (2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]-N-methylacetamido}-N-(2-hydroxyethyl)-3-phenylpropanamide::2-Ala-4-MePhe-5-Gly-Enkephalin::CHEMBL38874::D-Ala2-MePhe4-Met(0)5-enkephalin-ol::DAMGO::RX 783006::US11492374, ID 2::[3H]DAMGO::[tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephalin Mu-type opioid receptor Cavia cutleri 6 PDSP Ki 10.7270/Q2NC5ZPR 6248635 Leslie, FM; Chavkin, C; Cox, BM Stanford University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21015&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5462471 49689088 CHEMBL38874 1647 C04080 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 158998 CC(C)C[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C29H39N5O7/c1-17(2)13-24(29(40)41)34-28(39)23(15-19-7-5-4-6-8-19)33-25(36)16-31-26(37)18(3)32-27(38)22(30)14-20-9-11-21(35)12-10-20/h4-12,17-18,22-24,35H,13-16,30H2,1-3H3,(H,31,37)(H,32,38)(H,33,36)(H,34,39)(H,40,41)/t18-,22+,23+,24-/m1/s1 ZHUJMSMQIPIPTF-IBURTVSXSA-N 21025 (2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanamido]-4-methylpentanoic acid::(D-Ala2,D-Leu5)-Enkephalin::BW-180C::CHEMBL340032::DADLE::DADLE-OH::H-Tyr-D-Ala-Gly-Phe-D-Leu-OH::[D-Ala2-D-Leu5]enkephalin Mu-type opioid receptor Cavia cutleri 15.6 PDSP Ki 10.7270/Q2NC5ZPR 6248635 Leslie, FM; Chavkin, C; Cox, BM Stanford University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21025&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 6917707 49689098 CHEMBL340032 ZINC14952092 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 159001 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C29H39N5O7/c1-17(2)13-24(29(40)41)34-28(39)23(15-19-7-5-4-6-8-19)33-25(36)16-31-26(37)18(3)32-27(38)22(30)14-20-9-11-21(35)12-10-20/h4-12,17-18,22-24,35H,13-16,30H2,1-3H3,(H,31,37)(H,32,38)(H,33,36)(H,34,39)(H,40,41)/t18-,22+,23+,24+/m1/s1 ZHUJMSMQIPIPTF-JMBSJVKXSA-N 82090 DALLE Mu-type opioid receptor Cavia cutleri 18.2 PDSP Ki 10.7270/Q2NC5ZPR 6248635 Leslie, FM; Chavkin, C; Cox, BM Stanford University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82090 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82090&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10099522 131342664 ZINC14952096 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 159004 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1C3CC[C@@H]4O)ccc5O InChI=1S/C17H21NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2,4,10-11,13,16,19-20H,3,5-8H2,1H3/t10?,11-,13+,16+,17+/m1/s1 IJVCSMSMFSCRME-OONJBDFYSA-N 50021325 4-methyl-(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-triene-10,14-diol(DHM)::CHEMBL1281::DIHYDROMORPHINE Mu-type opioid receptor Cavia cutleri 1.94 PDSP Ki 10.7270/Q2NC5ZPR 6248635 Leslie, FM; Chavkin, C; Cox, BM Stanford University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021325&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25126776 103932033 CHEMBL1281 ZINC27625757 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 159007 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 2.69 PDSP Ki 10.7270/Q2NC5ZPR 6248635 Leslie, FM; Chavkin, C; Cox, BM Stanford University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 159010 Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1 UZHSEJADLWPNLE-GRGSLBFTSA-N 50000788 (morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(naloxone) 4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::(naloxone)4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::(naloxone)4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one (naloxone)::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one( Naloxone)::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(Naxolone)::4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(naloxone)C2H2O4::Analog of 14-(Arylhydroxyamino)codeinone::NALOXONE::NARCAN::SUBOXONE::[17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydroxymorphinan-6-one Mu-type opioid receptor Cavia cutleri 2.34 PDSP Ki 10.7270/Q2NC5ZPR 6248635 Leslie, FM; Chavkin, C; Cox, BM Stanford University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000788&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5284596 103915330 7459 DB01183 1676 C07252 ZINC00389747 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 174600 COc1cc(OC)c(cc1N[S](=O)(=O)c1ccc(cc1)C(F)(F)F)C(=O)CCCCN1CCC2(CC1)NC(=O)NC2=O InChI=1S/C27H31F3N4O7S/c1-40-22-16-23(41-2)20(33-42(38,39)18-8-6-17(7-9-18)27(28,29)30)15-19(22)21(35)5-3-4-12-34-13-10-26(11-14-34)24(36)31-25(37)32-26/h6-9,15-16,33H,3-5,10-14H2,1-2H3,(H2,31,32,36,37) HZZZZODVDSHQRG-UHFFFAOYSA-N 85098 N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)-1-oxopentyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)benzenesulfonamide::RS-102221 Mu-type opioid receptor Cavia cutleri >10000 PDSP Ki 10.1016/s0028-3908(97)00049-x 10.7270/Q2NV9GSN 9225287 Bonhaus, DW; Weinhardt, KK; Taylor, M; DeSouza, A; McNeeley, PM; Szczepanski, K; Fontana, DJ; Trinh, J; Rocha, CL; Dawson, MW; Flippin, LA; Eglen, RM Roche Bioscience http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85098 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85098&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3693566 136351198 187 ZINC26580328 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177729 COC(=O)\C=C\C(=O)NC1CC[C@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45 InChI=1S/C25H30N2O6/c1-32-20(30)7-6-19(29)26-16-8-9-25(31)18-12-15-4-5-17(28)22-21(15)24(25,23(16)33-22)10-11-27(18)13-14-2-3-14/h4-7,14,16,18,23,28,31H,2-3,8-13H2,1H3,(H,26,29)/b7-6+/t16?,18-,23+,24+,25+/m1/s1 PQKHESYTSKMWFP-IQUTTXILSA-N 82553 BETA-FUNALTREXAMINE::CAS_72786-10-8::b-FNA-HCl Mu-type opioid receptor Cavia cutleri 0.4 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82553 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82553&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 57339688 136350523 ZINC89455216 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177731 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)[C@@H](C)O)[C@@H](C)O)C(C)C)[C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(O)=O InChI=1S/C154H248N42O44S/c1-17-82(10)123(150(235)191-121(80(6)7)148(233)181-98(43-28-33-60-159)133(218)185-108(69-115(163)205)138(223)170-83(11)127(212)182-107(68-91-71-165-77-169-91)143(228)177-95(40-25-30-57-156)131(216)174-94(39-24-29-56-155)130(215)168-74-119(209)172-102(154(239)240)50-53-114(162)204)192-128(213)84(12)171-139(224)109(70-116(164)206)184-132(217)96(41-26-31-58-157)176-142(227)106(67-89-37-22-19-23-38-89)183-140(225)103(63-78(2)3)187-151(236)125(86(14)200)194-149(234)122(81(8)9)190-144(229)104(64-79(4)5)186-147(232)112-44-34-61-196(112)153(238)126(87(15)201)195-136(221)99(49-52-113(161)203)178-145(230)110(75-197)188-134(219)97(42-27-32-59-158)175-135(220)100(51-54-120(210)211)179-146(231)111(76-198)189-152(237)124(85(13)199)193-137(222)101(55-62-241-16)180-141(226)105(66-88-35-20-18-21-36-88)173-118(208)73-166-117(207)72-167-129(214)93(160)65-90-45-47-92(202)48-46-90/h18-23,35-38,45-48,71,77-87,93-112,121-126,197-202H,17,24-34,39-44,49-70,72-76,155-160H2,1-16H3,(H2,161,203)(H2,162,204)(H2,163,205)(H2,164,206)(H,165,169)(H,166,207)(H,167,214)(H,168,215)(H,170,223)(H,171,224)(H,172,209)(H,173,208)(H,174,216)(H,175,220)(H,176,227)(H,177,228)(H,178,230)(H,179,231)(H,180,226)(H,181,233)(H,182,212)(H,183,225)(H,184,217)(H,185,218)(H,186,232)(H,187,236)(H,188,219)(H,189,237)(H,190,229)(H,191,235)(H,192,213)(H,193,222)(H,194,234)(H,195,221)(H,210,211)(H,239,240)/t82-,83-,84-,85+,86+,87+,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,121-,122-,123-,124-,125-,126-/m0/s1 WAGZGJMGRRVHFE-XTLYPBBASA-N 81934 Beta-Endorphin Mu-type opioid receptor Cavia cutleri 2.3 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81934 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81934&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16144003 131342508 C02716 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177733 Oc1ccc2CC3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)C(C[C@@]35O)=Cc1ccccc1 InChI=1S/C27H27NO4/c29-20-9-8-18-13-21-27(31)14-19(12-16-4-2-1-3-5-16)23(30)25-26(27,22(18)24(20)32-25)10-11-28(21)15-17-6-7-17/h1-5,8-9,12,17,21,25,29,31H,6-7,10-11,13-15H2/t21?,25-,26-,27+/m0/s1 WXOUFNFMPVMGFZ-SSNGLDLMSA-N 50040485 15-benzyl-4-cyclopropylmethyl-10,17-dihydroxy-(1S,13R,15R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-trien-14-one::BNTX Mu-type opioid receptor Cavia cutleri 1.9 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040485 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040485&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44369694 103972528 ZINC03932773 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177735 CCC12CCN(CC3(O)CC3)C(Cc3ccc(O)cc13)C2(C)C InChI=1S/C20H29NO2/c1-4-20-9-10-21(13-19(23)7-8-19)17(18(20,2)3)11-14-5-6-15(22)12-16(14)20/h5-6,12,17,22-23H,4,7-11,13H2,1-3H3 ZDXGFIXMPOUDFF-UHFFFAOYSA-N 50013388 6-Ethyl-3-(1-hydroxy-cyclopropylmethyl)-11,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::BREMAZOCINE(-)::Bremazocine::CHEMBL350384 Mu-type opioid receptor Cavia cutleri 0.1 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013388 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013388&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 1223 103925603 CHEMBL350384 ZINC03870315 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177737 CO[C@@]12CC[C@@]3(C[C@@H]1[C@@](C)(O)C(C)(C)C)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45 InChI=1S/C29H41NO4/c1-25(2,3)26(4,32)20-15-27-10-11-29(20,33-5)24-28(27)12-13-30(16-17-6-7-17)21(27)14-18-8-9-19(31)23(34-24)22(18)28/h8-9,17,20-21,24,31-32H,6-7,10-16H2,1-5H3/t20-,21-,24-,26-,27-,28+,29+/m1/s1 RMRJXGBAOAMLHD-AGMYMXDYSA-N 50028147 2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(14R)-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-16-yl]-3,3-dimethyl-2-butanol::2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(15S)-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-16-yl]-3,3-dimethyl-2-butanol(Buprenorphine)::BUPRENORPHINE::Buprenorphine(+)::Buprenorphine(-)::Buprenorphine2-(3-cyclopropylmethyl-11-hydroxy-15-methoxy-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-16-yl)-3,3-dimethyl-2-butanol(::CHEMBL560511 Mu-type opioid receptor Cavia cutleri 1.3 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028147 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028147&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9811785 103937516 CHEMBL560511 C08007 ZINC38156722 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177739 COc1ccc2CC3C4C=CC(O)C5Oc1c2C45CCN3C InChI=1S/C18H21NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3-6,11-13,17,20H,7-9H2,1-2H3 OROGSEYTTFOCAN-UHFFFAOYSA-N 82266 CAS_29485-83-4::CODEINE SULFATE::Codeine::NSC_223652 Mu-type opioid receptor Cavia cutleri 152 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82266 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82266&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 2828 136350238 ZINC03830598 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177741 C[C@@H](O)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CS)NC(=O)[C@H](N)Cc1ccccc1)[C@@H](C)O)C(C)(C)S)C(N)=O InChI=1S/C51H71N13O11S2/c1-26(65)39(42(53)68)62-49(75)41(51(3,4)77)64-48(74)40(27(2)66)63-44(70)35(15-10-20-56-50(54)55)58-46(72)37(23-30-24-57-34-14-9-8-13-32(30)34)60-45(71)36(22-29-16-18-31(67)19-17-29)59-47(73)38(25-76)61-43(69)33(52)21-28-11-6-5-7-12-28/h5-9,11-14,16-19,24,26-27,33,35-41,57,65-67,76-77H,10,15,20-23,25,52H2,1-4H3,(H2,53,68)(H,58,72)(H,59,73)(H,60,71)(H,61,69)(H,62,75)(H,63,70)(H,64,74)(H4,54,55,56)/t26-,27-,33-,35+,36+,37-,38+,39+,40+,41-/m1/s1 GLWPFSWTTGSQRY-FGHAYEPSSA-N 85334 CTAP-NH2 Mu-type opioid receptor Cavia cutleri 0.5 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85334 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85334&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11804285 136351434 C02248 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177743 C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C18H25NO/c1-12-17-9-14-5-6-15(20)10-16(14)18(12,2)7-8-19(17)11-13-3-4-13/h5-6,10,12-13,17,20H,3-4,7-9,11H2,1-2H3/t12-,17+,18+/m1/s1 YQYVFVRQLZMJKJ-UUWFMWQGSA-N 50001022 (2S,6S,11S)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::(SSS)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyclo[9.1.1.0*3,8*]trideca-3(8),4,6-trien-6-ol(cyclazocine)::3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL293349::CYCLAZOCINE (-)::Cyclazocine::Cyclazocine (+) Mu-type opioid receptor Cavia cutleri 0.1 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001022 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001022&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603759 103915555 CHEMBL293349 ZINC07996837 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177745 CC(C)C[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C29H39N5O7/c1-17(2)13-24(29(40)41)34-28(39)23(15-19-7-5-4-6-8-19)33-25(36)16-31-26(37)18(3)32-27(38)22(30)14-20-9-11-21(35)12-10-20/h4-12,17-18,22-24,35H,13-16,30H2,1-3H3,(H,31,37)(H,32,38)(H,33,36)(H,34,39)(H,40,41)/t18-,22+,23+,24-/m1/s1 ZHUJMSMQIPIPTF-IBURTVSXSA-N 21025 (2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanamido]-4-methylpentanoic acid::(D-Ala2,D-Leu5)-Enkephalin::BW-180C::CHEMBL340032::DADLE::DADLE-OH::H-Tyr-D-Ala-Gly-Phe-D-Leu-OH::[D-Ala2-D-Leu5]enkephalin Mu-type opioid receptor Cavia cutleri 3.2 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21025&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 6917707 49689098 CHEMBL340032 ZINC14952092 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177747 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C)[C@@H](Cc1ccccc1)C(=O)NCCO InChI=1S/C26H35N5O6/c1-17(30-25(36)21(27)14-19-8-10-20(33)11-9-19)24(35)29-16-23(34)31(2)22(26(37)28-12-13-32)15-18-6-4-3-5-7-18/h3-11,17,21-22,32-33H,12-16,27H2,1-2H3,(H,28,37)(H,29,35)(H,30,36)/t17-,21+,22+/m1/s1 HPZJMUBDEAMBFI-WTNAPCKOSA-N 21015 (2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]-N-methylacetamido}-N-(2-hydroxyethyl)-3-phenylpropanamide::2-Ala-4-MePhe-5-Gly-Enkephalin::CHEMBL38874::D-Ala2-MePhe4-Met(0)5-enkephalin-ol::DAMGO::RX 783006::US11492374, ID 2::[3H]DAMGO::[tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephalin Mu-type opioid receptor Cavia cutleri 1.1 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21015&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5462471 49689088 CHEMBL38874 1647 C04080 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177750 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1C3CC[C@@H]4O)ccc5O InChI=1S/C17H21NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2,4,10-11,13,16,19-20H,3,5-8H2,1H3/t10?,11-,13+,16+,17+/m1/s1 IJVCSMSMFSCRME-OONJBDFYSA-N 50021325 4-methyl-(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-triene-10,14-diol(DHM)::CHEMBL1281::DIHYDROMORPHINE Mu-type opioid receptor Cavia cutleri 0.8 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021325&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25126776 103932033 CHEMBL1281 ZINC27625757 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177752 CO[C@]12CC[C@@]3(C[C@@H]1C(C)(C)O)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45 InChI=1S/C26H35NO4/c1-23(2,29)18-13-24-8-9-26(18,30-3)22-25(24)10-11-27(14-15-4-5-15)19(24)12-16-6-7-17(28)21(31-22)20(16)25/h6-7,15,18-19,22,28-29H,4-5,8-14H2,1-3H3/t18-,19-,22-,24-,25+,26-/m1/s1 OIJXLIIMXHRJJH-KNLIIKEYSA-N 50001714 2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1S,2R,6S,14R,15R,16R)-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-16-yl]-2-propanol::2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1S,2R,6S,14R,15R,16R)-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-16-yl]-2-propanol(diprenorphine)::2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7(12),8,10-trien-16-yl]-2-propanol::CHEMBL281786::DIPRENORPHINE-HCl::Diprenorphine Mu-type opioid receptor Cavia cutleri 0.2 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001714 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001714&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 443408 103916129 CHEMBL281786 C11794 ZINC04102215 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177753 CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21-,23-,24-/m0/s1 MCMMCRYPQBNCPH-WMIMKTLMSA-N 21008 (4S,7S,13S)-13-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid::CHEMBL31421::DPDPE::DPDPE-Cl::DPDPE-OH::Enkephalin, [Tyrosyl-2,6-3H(N)]- (2-D-Penicillamine, 5-D-Penicillamine)::[3H]DPDPE Mu-type opioid receptor Cavia cutleri 180 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21008 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21008&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 104787 49689081 73356 CHEMBL31421 1608 ZINC29206920 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177755 CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21-,23-,24-/m0/s1 MCMMCRYPQBNCPH-WMIMKTLMSA-N 21008 (4S,7S,13S)-13-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid::CHEMBL31421::DPDPE::DPDPE-Cl::DPDPE-OH::Enkephalin, [Tyrosyl-2,6-3H(N)]- (2-D-Penicillamine, 5-D-Penicillamine)::[3H]DPDPE Mu-type opioid receptor Cavia cutleri >10000 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21008 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21008&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 104787 49689081 73356 CHEMBL31421 1608 ZINC29206920 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177757 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](CO)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H]([C@@H](C)O)C(O)=O InChI=1S/C33H46N6O10/c1-18(2)13-24(32(47)39-28(19(3)41)33(48)49)37-31(46)25(15-20-7-5-4-6-8-20)36-27(43)16-35-30(45)26(17-40)38-29(44)23(34)14-21-9-11-22(42)12-10-21/h4-12,18-19,23-26,28,40-42H,13-17,34H2,1-3H3,(H,35,45)(H,36,43)(H,37,46)(H,38,44)(H,39,47)(H,48,49)/t19-,23+,24+,25+,26-,28+/m1/s1 PKSODCLCMBUCPW-LVNBQDLPSA-N 50018708 2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-3-hydroxy-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-3-hydroxy-butyric acid::CHEMBL124283::DSLET::DSLET-OH::Tyr-D-Ser-Gly-Phe-Leu-Thr Mu-type opioid receptor Cavia cutleri 20.6 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018708 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018708&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 107847 103929785 CHEMBL124283 1609 C06396 ZINC27215004 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177759 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(O)=O InChI=1S/C74H115N21O17/c1-40(2)34-53(91-68(107)54(36-44-18-10-8-11-19-44)86-58(100)39-84-57(99)38-85-62(101)48(76)35-46-25-27-47(97)28-26-46)67(106)89-51(24-17-33-83-74(80)81)63(102)87-50(23-16-32-82-73(78)79)64(103)90-52(29-30-56(77)98)65(104)92-55(37-45-20-12-9-13-21-45)69(108)88-49(22-14-15-31-75)66(105)93-59(41(3)4)70(109)94-60(42(5)6)71(110)95-61(43(7)96)72(111)112/h8-13,18-21,25-28,40-43,48-55,59-61,96-97H,14-17,22-24,29-39,75-76H2,1-7H3,(H2,77,98)(H,84,99)(H,85,101)(H,86,100)(H,87,102)(H,88,108)(H,89,106)(H,90,103)(H,91,107)(H,92,104)(H,93,105)(H,94,109)(H,95,110)(H,111,112)(H4,78,79,82)(H4,80,81,83)/t43-,48+,49+,50+,51+,52+,53+,54+,55+,59+,60+,61+/m1/s1 AGTSSZRZBSNTGQ-ITZCFHCWSA-N 85325 DYNORPHIN B-OH::Dynorphin B (1-13) Mu-type opioid receptor Cavia cutleri 5.5 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85325&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25075991 136351425 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177761 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C64H105N21O13/c1-6-37(4)51(59(95)81-45(21-14-30-75-64(71)72)60(96)85-31-15-22-49(85)58(94)82-46(61(97)98)18-10-11-27-65)84-55(91)44(20-13-29-74-63(69)70)79-54(90)43(19-12-28-73-62(67)68)80-56(92)47(32-36(2)3)83-57(93)48(34-39-16-8-7-9-17-39)78-50(87)35-76-52(88)38(5)77-53(89)42(66)33-40-23-25-41(86)26-24-40/h7-9,16-17,23-26,36-38,42-49,51,86H,6,10-15,18-22,27-35,65-66H2,1-5H3,(H,76,88)(H,77,89)(H,78,87)(H,79,90)(H,80,92)(H,81,95)(H,82,94)(H,83,93)(H,84,91)(H,97,98)(H4,67,68,73)(H4,69,70,74)(H4,71,72,75)/t37-,38+,42-,43-,44-,45-,46-,47-,48-,49-,51-/m0/s1 VTPKWYYFTHZENR-DFQGMJKVSA-N 85333 DYNORPHIN(1-11)-OH Mu-type opioid receptor Cavia cutleri 2.3 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85333 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85333&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5490755 136351433 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177763 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C75H126N24O15/c1-7-45(6)61(70(111)94-53(25-17-35-87-75(83)84)71(112)99-36-18-26-58(99)69(110)93-50(21-11-13-31-76)64(105)96-56(38-44(4)5)67(108)95-54(72(113)114)22-12-14-32-77)98-65(106)52(24-16-34-86-74(81)82)91-63(104)51(23-15-33-85-73(79)80)92-66(107)55(37-43(2)3)97-68(109)57(40-46-19-9-8-10-20-46)90-60(102)42-88-59(101)41-89-62(103)49(78)39-47-27-29-48(100)30-28-47/h8-10,19-20,27-30,43-45,49-58,61,100H,7,11-18,21-26,31-42,76-78H2,1-6H3,(H,88,101)(H,89,103)(H,90,102)(H,91,104)(H,92,107)(H,93,110)(H,94,111)(H,95,108)(H,96,105)(H,97,109)(H,98,106)(H,113,114)(H4,79,80,85)(H4,81,82,86)(H4,83,84,87)/t45-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,61-/m0/s1 OVVIBUHLQIYUEU-IWIISZHXSA-N 224024 BDBM50241435::Dynorphin A (1-13)::YGGFLRRXRPKLK Mu-type opioid receptor Cavia cutleri 3.3 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=224024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=224024&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25075996 374884564 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177765 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(O)=O InChI=1S/C99H155N31O23/c1-7-55(6)81(129-86(142)66(28-18-40-112-98(107)108)118-83(139)65(27-17-39-111-97(105)106)120-88(144)70(44-54(4)5)125-89(145)71(46-56-21-9-8-10-22-56)117-79(135)52-115-78(134)51-116-82(138)61(102)45-57-31-33-59(131)34-32-57)94(150)122-67(29-19-41-113-99(109)110)95(151)130-42-20-30-75(130)93(149)121-64(26-14-16-38-101)85(141)124-69(43-53(2)3)87(143)119-63(25-13-15-37-100)84(140)126-72(47-58-50-114-62-24-12-11-23-60(58)62)90(146)128-74(49-80(136)137)92(148)127-73(48-77(104)133)91(147)123-68(96(152)153)35-36-76(103)132/h8-12,21-24,31-34,50,53-55,61,63-75,81,114,131H,7,13-20,25-30,35-49,51-52,100-102H2,1-6H3,(H2,103,132)(H2,104,133)(H,115,134)(H,116,138)(H,117,135)(H,118,139)(H,119,143)(H,120,144)(H,121,149)(H,122,150)(H,123,147)(H,124,141)(H,125,145)(H,126,140)(H,127,148)(H,128,146)(H,129,142)(H,136,137)(H,152,153)(H4,105,106,111)(H4,107,108,112)(H4,109,110,113)/t55-,61-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,81-/m0/s1 JMNJYGMAUMANNW-FIXZTSJVSA-N 50010702 CHEMBL411557::DYNORPHIN(1-17)-OH::Dynorphin A (1-17)::H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln-OH::Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln::dynorphin A Mu-type opioid receptor Cavia cutleri 8.1 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010702&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 91928823 103923448 CHEMBL411557 C02716 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177768 CC[C@]12CCN(CC3CC3)C([C@@H]1C)C(=O)c1ccc(O)cc21 InChI=1S/C19H25NO2/c1-3-19-8-9-20(11-13-4-5-13)17(12(19)2)18(22)15-7-6-14(21)10-16(15)19/h6-7,10,12-13,17,21H,3-5,8-9,11H2,1-2H3/t12-,17?,19-/m0/s1 SEJUQQOPVAUETF-BKBNBNODSA-N 50000091 (6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::(6S,11R)-3-Cyclopropylmethyl-9-hydroxy-6,11-dimethyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one (ethylketocyclazocine)::3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one(Ethylketazocine, EKC)::CHEMBL279968::EKC::EKC(-) Mu-type opioid receptor Cavia cutleri 0.4 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000091&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44273397 103914788 CHEMBL279968 ZINC00967957 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177770 CCOc1ccc(Cc2nc3cc(ccc3n2CCN(CC)CC)[N+]([O-])=O)cc1 InChI=1S/C22H28N4O3/c1-4-24(5-2)13-14-25-21-12-9-18(26(27)28)16-20(21)23-22(25)15-17-7-10-19(11-8-17)29-6-3/h7-12,16H,4-6,13-15H2,1-3H3 PXDBZSCGSQSKST-UHFFFAOYSA-N 50013847 CHEMBL312040::Etonitazene::{2-[2-(4-Ethoxy-benzyl)-5-nitro-benzoimidazol-1-yl]-ethyl}-diethyl-amine Mu-type opioid receptor Cavia cutleri 1.6 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013847&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 13493 103925881 CHEMBL312040 DB01462 1624 ZINC04215955 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177772 CCCC(C)(O)C1CC23C=CC1(OC)C1Oc4c5c(CC2N(C)CCC315)ccc4O InChI=1S/C25H33NO4/c1-5-8-22(2,28)17-14-23-9-10-25(17,29-4)21-24(23)11-12-26(3)18(23)13-15-6-7-16(27)20(30-21)19(15)24/h6-7,9-10,17-18,21,27-28H,5,8,11-14H2,1-4H3 CAHCBJPUTCKATP-UHFFFAOYSA-N 82425 CAS_61677::ETORPHINE - HCI::NSC_61677 Mu-type opioid receptor Cavia cutleri 1.5 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82425 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82425&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 518962 136350396 ZINC05649422 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177774 CCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 InChI=1S/C22H28N2O/c1-2-22(25)24(20-11-7-4-8-12-20)21-14-17-23(18-15-21)16-13-19-9-5-3-6-10-19/h3-12,21H,2,13-18H2,1H3 PJMPHNIQZUBGLI-UHFFFAOYSA-N 50008984 4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-phthalazin-1-one::CHEMBL596::Duragesic-100::Duragesic-12::Duragesic-25::Duragesic-50::Duragesic-75::FENTANYL::FENTANYL CITRATE::FENTANYL-HCl::Fentanyl-100::Fentanyl-12::Fentanyl-25::Fentanyl-50::Fentanyl-75::Fentora::Innovar::Ionsys::N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide::N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide(Fentanyl)::N-(1-phenethylpiperidin-4-yl)-N-phenylpropionamide Mu-type opioid receptor Cavia cutleri 1 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008984&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 7V7 5TZO,8EF5,7U64 3345 103922051 119915 CHEMBL596 DB00813 1626 ZINC02522669 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177776 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C28H37N5O7/c1-17(2)12-23(28(39)40)33-27(38)22(14-18-6-4-3-5-7-18)32-25(36)16-30-24(35)15-31-26(37)21(29)13-19-8-10-20(34)11-9-19/h3-11,17,21-23,34H,12-16,29H2,1-2H3,(H,30,35)(H,31,37)(H,32,36)(H,33,38)(H,39,40)/t21-,22-,23-/m0/s1 URLZCHNOLZSCCA-VABKMULXSA-N 50001465 (S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::([Leu]-enkephalin)2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::(enkephalin)2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-1-oxo-3-phenyl-propylamino]-4-methyl-pentanoic acid::2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::2-[1-[1-amino-2-(4-hydroxyphenyl)-(1S)-ethylcarboxamidomethylcarboxamidomethylcarboxamido]-2-phenyl-(1S)-ethylcarboxamido]-4-methyl-(2S)-pentanoic acid::2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid(Enkephalin)::2-{1-[1-amino-2-(4-hydroxyphenyl)ethylcarboxamidomethylcarboxamidomethylcarboxamido]-2-phenylethylcarboxamido}-4-methylpentanoic acid::CHEMBL8234::ENKEPHALIN::Leu-ENKEPHALIN::Leu5-Enkephalin::Tyr-Gly-Gly-Phe-Leu-OH Mu-type opioid receptor Cavia cutleri 21.7 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001465&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 461776 103915930 CHEMBL8234 ZINC14952116 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177778 CN1CC[C@]23CCCC[C@H]2[C@H]1Cc1ccc(O)cc31 InChI=1S/C17H23NO/c1-18-9-8-17-7-3-2-4-14(17)16(18)10-12-5-6-13(19)11-15(12)17/h5-6,11,14,16,19H,2-4,7-10H2,1H3/t14-,16+,17+/m0/s1 JAQUASYNZVUNQP-USXIJHARSA-N 82427 CAS_5985-38-6::LEVORPHANOL-tartarate Mu-type opioid receptor Cavia cutleri 0.3 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82427 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82427&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5359272 136350398 DB00854 C08014 ZINC03812984 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177780 CCC(=O)C(CC(C)N(C)C)(c1ccccc1)c1ccccc1 InChI=1S/C21H27NO/c1-5-20(23)21(16-17(2)22(3)4,18-12-8-6-9-13-18)19-14-10-7-11-15-19/h6-15,17H,5,16H2,1-4H3 USSIQXCVUWKGNF-UHFFFAOYSA-N 82507 (+/-)-Methadone::CAS_5967-73-7::METHADONE::Methadone-HCL,(-)::NSC_22266 Mu-type opioid receptor Cavia cutleri 1.4 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82507 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82507&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 4095 136350478 50140 DB00333 C07163 ZINC01530707 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177782 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 2 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177784 Oc1ccc2CC3N(CC=C)CCC45[C@H](Oc1c24)C(CCC35O)=NNC(=O)c1ccccc1 InChI=1S/C26H27N3O4/c1-2-13-29-14-12-25-21-17-8-9-19(30)22(21)33-23(25)18(10-11-26(25,32)20(29)15-17)27-28-24(31)16-6-4-3-5-7-16/h2-9,20,23,30,32H,1,10-15H2,(H,28,31)/t20?,23-,25?,26?/m1/s1 AKXCFAYOTIEFOH-MJZKPUTMSA-N 50189257 CHEMBL378753::NalBzOH Mu-type opioid receptor Cavia cutleri 0.2 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189257&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44414890 104072943 CHEMBL378753 ZINC03874473 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177786 Oc1ccc2CC3N(CC4CC4)CCC45C(Oc1c24)C(=C)CCC35O InChI=1S/C21H25NO3/c1-12-6-7-21(24)16-10-14-4-5-15(23)18-17(14)20(21,19(12)25-18)8-9-22(16)11-13-2-3-13/h4-5,13,16,19,23-24H,1-3,6-11H2 WJBLNOPPDWQMCH-UHFFFAOYSA-N 85326 CAS_119501::NALMEFENE-HCl::NSC_119501::nalmefene Mu-type opioid receptor Cavia cutleri 0.3 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85326 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85326&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 4422 136351426 ZINC03831179 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177788 O[C@H]1C=CC2[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC=C)c45 InChI=1S/C19H21NO3/c1-2-8-20-9-7-19-12-4-6-15(22)18(19)23-17-14(21)5-3-11(16(17)19)10-13(12)20/h2-6,12-13,15,18,21-22H,1,7-10H2/t12?,13-,15+,18+,19+/m1/s1 UIQMVEYFGZJHCZ-OQRBEVHLSA-N 50021560 4-allyl-(13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol:hydrocholride(Nalorphine)::4-allyl-(1S,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol; Hydrochloride(Nalorphine)::4-allyl-(1S,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolhydrochloride(Nalorphine hydrochloride)::4-allyl-(5R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; hydrochloride(Nalorphine hydrochloride)::CHEMBL553080::NALORPHINE - HCI Mu-type opioid receptor Cavia cutleri 1.9 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021560 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021560&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 12313112 103932261 CHEMBL553080 ZINC26259212 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177790 Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1 UZHSEJADLWPNLE-GRGSLBFTSA-N 50000788 (morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(naloxone) 4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::(naloxone)4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::(naloxone)4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one (naloxone)::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one( Naloxone)::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(Naxolone)::4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(naloxone)C2H2O4::Analog of 14-(Arylhydroxyamino)codeinone::NALOXONE::NARCAN::SUBOXONE::[17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydroxymorphinan-6-one Mu-type opioid receptor Cavia cutleri 1.5 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000788&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5284596 103915330 7459 DB01183 1676 C07252 ZINC00389747 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177792 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1 DQCKKXVULJGBQN-XFWGSAIBSA-N 60212 (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::MLS000069607::NALTREXONE HYDROCHLORIDE::SMR000058767::US10988481, Compound NTX::US9107954, naltrexone::cid_5485201 Mu-type opioid receptor Cavia cutleri 0.4 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60212&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5360515 252639834 DB00704 C07253 ZINC00001773 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177794 Oc1ccc2C[C@H]3N(CC4CC4)CCC45C(Oc1c24)c1[nH]c2ccccc2c1CC35O InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1 WIYUZYBFCWCCQJ-XEWUMVRVSA-N 21864 (21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.0^{1,13}.0^{2,21}.0^{4,12}.0^{5,10}.0^{19,25}]pentacosa-4(12),5,7,9,15,17,19(25)-heptaene-2,16-diol::(8R)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol::NALTRINDOLE::[3H]-naltrindole Mu-type opioid receptor Cavia cutleri 0.2 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21864&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3034754 49700969 ZINC62153992 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177796 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2[C@@H]4Oc6c7c(C[C@H]8N(CC9CC9)CC[C@@]47[C@@]8(O)Cc2c1C[C@@]35O)ccc6O InChI=1S/C40H43N3O6/c44-25-7-5-21-13-27-39(46)15-23-24-16-40(47)28-14-22-6-8-26(45)34-30(22)38(40,10-12-43(28)18-20-3-4-20)36(49-34)32(24)41-31(23)35-37(39,29(21)33(25)48-35)9-11-42(27)17-19-1-2-19/h5-8,19-20,27-28,35-36,41,44-47H,1-4,9-18H2/t27-,28-,35+,36+,37+,38+,39-,40-/m1/s1 APSUXPSYBJVPPS-YAUKWVCOSA-N 82551 C18130::CAS_105618-26-6::NOR-BNI (HCI)2::NORBNI Mu-type opioid receptor Cavia cutleri 8.3 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82551&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5480230 136350521 C18130 ZINC03995590 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177798 OC1C=CC2C3Cc4ccc(O)c5OC1C2(CCN3)c45 InChI=1S/C16H17NO3/c18-11-3-1-8-7-10-9-2-4-12(19)15-16(9,5-6-17-10)13(8)14(11)20-15/h1-4,9-10,12,15,17-19H,5-7H2 ONBWJWYUHXVEJS-UHFFFAOYSA-N 85329 NORMORPHINE Mu-type opioid receptor Cavia cutleri 3.9 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85329 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85329&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 430245 136351429 1630 ZINC05440560 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177800 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1oc2ccccc2c1C[C@@]35O InChI=1S/C26H25NO4/c28-18-8-7-15-11-20-26(29)12-17-16-3-1-2-4-19(16)30-22(17)24-25(26,21(15)23(18)31-24)9-10-27(20)13-14-5-6-14/h1-4,7-8,14,20,24,28-29H,5-6,9-13H2/t20-,24+,25+,26-/m1/s1 ZHVWWEYETMPAMX-IFKAHUTRSA-N 82552 CAS_111555-58-9::NTB::naltrindolebenzofuran Mu-type opioid receptor Cavia cutleri 6.5 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82552 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82552&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search ZY8 8SI5,8SI6 5486827 136350522 ZINC03874478 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177802 C[C@H]1[C@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CC=C(C)C InChI=1S/C19H27NO/c1-13(2)7-9-20-10-8-19(4)14(3)18(20)11-15-5-6-16(21)12-17(15)19/h5-7,12,14,18,21H,8-11H2,1-4H3/t14-,18+,19+/m0/s1 VOKSWYLNZZRQPF-GDIGMMSISA-N 50001028 (+)-PENTAZOCINE::(-)-pentazocine::(2R,6R,11R)-6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::(6R,11S)-6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Pentazocine)::CHEMBL560::PENTAZOCINE (+)::PENTAZOCINE (-)::Pentazocine::Pentazocine,(+/-)::Talacen::Talwin::US10231963, Table B.8::US10736890, Compound TABLE B.8::US11534436, Compound Table B.8::US9656961, Example 00125::rel-(2R,6R,11R)-6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol Mu-type opioid receptor Cavia cutleri 5.7 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001028&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 441278 103915561 CHEMBL560 DB00652 1606 C07421 ZINC00000596 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177804 CN([C@H](Cc1ccccc1)C(=O)N1CCC[C@@H]1C(N)=O)C(=O)C1CCCN1C(=O)C(N)Cc1ccc(O)cc1 InChI=1S/C29H37N5O5/c1-32(25(18-19-7-3-2-4-8-19)29(39)33-15-5-9-23(33)26(31)36)28(38)24-10-6-16-34(24)27(37)22(30)17-20-11-13-21(35)14-12-20/h2-4,7-8,11-14,22-25,35H,5-6,9-10,15-18,30H2,1H3,(H2,31,36)/t22?,23-,24?,25-/m1/s1 JAKBYSTWCHUQOK-RULIFZQXSA-N 50044897 CHEMBL163808::PL017::Tyr-Pro-D-(NMe)Phe-D-Pro-NH2 Mu-type opioid receptor Cavia cutleri 8.1 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044897 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044897&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44375783 103976005 CHEMBL163808 ZINC27842551 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177806 N[C@@H](Cc1ccc(O)cc1)C(=O)N1Cc2ccccc2C[C@H]1CN[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O InChI=1S/C37H40N4O5/c38-32(19-27-15-17-31(42)18-16-27)36(44)41-24-29-14-8-7-13-28(29)22-30(41)23-39-33(20-25-9-3-1-4-10-25)35(43)40-34(37(45)46)21-26-11-5-2-6-12-26/h1-18,30,32-34,39,42H,19-24,38H2,(H,40,43)(H,45,46)/t30-,32-,33-,34-/m0/s1 RPKMHCAOERKVEC-DYTOPAQESA-N 85328 TIPP-PSI::TIPPpsi Mu-type opioid receptor Cavia cutleri >10000 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85328 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85328&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311481 136351428 ZINC65731305 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177808 CN(C1CCCC[C@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C19H26Cl2N2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17?,18-/m1/s1 VQLPLYSROCPWFF-QRWMCTBCSA-N 50169774 2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide; compound with methanesulfonic acid::CHEMBL360943::U-50488H::U50,488H Mu-type opioid receptor Cavia cutleri 294 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50169774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50169774&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 68616 104054543 CHEMBL360943 C11796 ZINC00643032 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177810 CN([C@H]1CC[C@@]2(CCCO2)C[C@@H]1N1CCCC1)C(=O)Cc1ccccc1 InChI=1S/C22H32N2O2/c1-23(21(25)16-18-8-3-2-4-9-18)19-10-12-22(11-7-15-26-22)17-20(19)24-13-5-6-14-24/h2-4,8-9,19-20H,5-7,10-17H2,1H3/t19-,20-,22-/m0/s1 PGZRDDYTKFZSFR-ONTIZHBOSA-N 21130 N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl)-1-oxaspiro[4.5]decan-8-yl]acetamide::N-methyl-N-(7-(1-pyrrolidinyl)-1-oxaspiro(4,5)dec-8-yl)benzeneacetamide::U-69593::U69,593::[3H]U69593 Mu-type opioid receptor Cavia cutleri 692 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21130&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 105104 49689203 73357 1655 ZINC02517042 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 177812 CN1CCC2(C)c3cc(O)ccc3CC1C2(C)CCC(=O)CCC1CCCC1 InChI=1S/C25H37NO2/c1-24-14-15-26(3)23(16-19-9-11-21(28)17-22(19)24)25(24,2)13-12-20(27)10-8-18-6-4-5-7-18/h9,11,17-18,23,28H,4-8,10,12-16H2,1-3H3 LOYWOYCPSWPKFH-UHFFFAOYSA-N 85331 CAS_115077::NSC_115077::WIN 44,441(-) Mu-type opioid receptor Cavia cutleri 0.1 PDSP Ki 10.7270/Q23J3BH2 9686407 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS SRI International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85331 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85331&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10322880 136351431 ZINC06032293 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 181514 NCCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O InChI=1S/C30H45N9O5/c31-15-5-4-9-23(26(33)41)37-29(44)25(18-19-7-2-1-3-8-19)39-28(43)24(10-6-16-36-30(34)35)38-27(42)22(32)17-20-11-13-21(40)14-12-20/h1-3,7-8,11-14,22-25,40H,4-6,9-10,15-18,31-32H2,(H2,33,41)(H,37,44)(H,38,42)(H,39,43)(H4,34,35,36)/t22-,23-,24+,25-/m0/s1 UEVAHGMTRWGMTB-JBXUNAHCSA-N 85737 CAS_122222::DALDA::NSC_122222 Mu-type opioid receptor Cavia cutleri 1.69 PDSP Ki 10.1016/s0223-5234(00)01171-5 10.7270/Q23X856N 11121615 Schiller, PW; Nguyen, TM; Berezowska, I; Dupuis, S; Weltrowska, G; Chung, NN; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85737&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 122222 136351837 ZINC14951239 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 181515 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCN)C(N)=O InChI=1S/C30H45N9O5/c1-17-13-20(40)14-18(2)21(17)16-22(32)27(42)38-24(9-6-12-36-30(34)35)28(43)39-25(15-19-7-4-3-5-8-19)29(44)37-23(10-11-31)26(33)41/h3-5,7-8,13-14,22-25,40H,6,9-12,15-16,31-32H2,1-2H3,(H2,33,41)(H,37,44)(H,38,42)(H,39,43)(H4,34,35,36)/t22-,23-,24+,25-/m0/s1 PDGOKQOUTUDKQQ-JBXUNAHCSA-N 85733 H-Dmt-D-Arg-Phe-A2bu-NH2 Mu-type opioid receptor Cavia cutleri 0.803 PDSP Ki 10.1016/s0223-5234(00)01171-5 10.7270/Q23X856N 11121615 Schiller, PW; Nguyen, TM; Berezowska, I; Dupuis, S; Weltrowska, G; Chung, NN; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85733 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85733&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15458892 136351833 ZINC67961491 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 181516 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN)C(N)=O InChI=1S/C31H47N9O5/c1-18-14-21(41)15-19(2)22(18)17-23(33)28(43)39-25(11-7-13-37-31(35)36)29(44)40-26(16-20-8-4-3-5-9-20)30(45)38-24(27(34)42)10-6-12-32/h3-5,8-9,14-15,23-26,41H,6-7,10-13,16-17,32-33H2,1-2H3,(H2,34,42)(H,38,45)(H,39,43)(H,40,44)(H4,35,36,37)/t23-,24-,25+,26-/m0/s1 YJZGZJUNCTZJLV-SSUZURRFSA-N 85736 Dmt-d-Arg-Phe-Orn-NH2::H-Dmt-D-Arg-Phe-Orn-NH2 Mu-type opioid receptor Cavia cutleri 0.151 PDSP Ki 10.1016/s0223-5234(00)01171-5 10.7270/Q23X856N 11121615 Schiller, PW; Nguyen, TM; Berezowska, I; Dupuis, S; Weltrowska, G; Chung, NN; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85736 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85736&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9809338 136351836 ZINC67961490 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 181517 Cc1cc(O)ccc1C[C@H](N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C31H47N9O5/c1-19-16-22(41)13-12-21(19)18-23(33)28(43)39-25(11-7-15-37-31(35)36)29(44)40-26(17-20-8-3-2-4-9-20)30(45)38-24(27(34)42)10-5-6-14-32/h2-4,8-9,12-13,16,23-26,41H,5-7,10-11,14-15,17-18,32-33H2,1H3,(H2,34,42)(H,38,45)(H,39,43)(H,40,44)(H4,35,36,37)/t23-,24-,25+,26-/m0/s1 VDYDFOLHCMWLDM-SSUZURRFSA-N 85734 H-Hmt-D-Arg-Phe-Lys-NH2 I::H-Hmt-D-Arg-Phe-Lys-NH2 II::H-Mmt-D-Arg-Phe-Lys-NH2 Mu-type opioid receptor Cavia cutleri 1.76 PDSP Ki 10.1016/s0223-5234(00)01171-5 10.7270/Q23X856N 11121615 Schiller, PW; Nguyen, TM; Berezowska, I; Dupuis, S; Weltrowska, G; Chung, NN; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85734&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9809339 136351834 ZINC67961492 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 181518 Cc1cc(O)ccc1C[C@H](N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C31H47N9O5/c1-19-16-22(41)13-12-21(19)18-23(33)28(43)39-25(11-7-15-37-31(35)36)29(44)40-26(17-20-8-3-2-4-9-20)30(45)38-24(27(34)42)10-5-6-14-32/h2-4,8-9,12-13,16,23-26,41H,5-7,10-11,14-15,17-18,32-33H2,1H3,(H2,34,42)(H,38,45)(H,39,43)(H,40,44)(H4,35,36,37)/t23-,24-,25+,26-/m0/s1 VDYDFOLHCMWLDM-SSUZURRFSA-N 85734 H-Hmt-D-Arg-Phe-Lys-NH2 I::H-Hmt-D-Arg-Phe-Lys-NH2 II::H-Mmt-D-Arg-Phe-Lys-NH2 Mu-type opioid receptor Cavia cutleri 11.3 PDSP Ki 10.1016/s0223-5234(00)01171-5 10.7270/Q23X856N 11121615 Schiller, PW; Nguyen, TM; Berezowska, I; Dupuis, S; Weltrowska, G; Chung, NN; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85734&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9809339 136351834 ZINC67961492 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 181519 Cc1cc(O)ccc1C[C@H](N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C31H47N9O5/c1-19-16-22(41)13-12-21(19)18-23(33)28(43)39-25(11-7-15-37-31(35)36)29(44)40-26(17-20-8-3-2-4-9-20)30(45)38-24(27(34)42)10-5-6-14-32/h2-4,8-9,12-13,16,23-26,41H,5-7,10-11,14-15,17-18,32-33H2,1H3,(H2,34,42)(H,38,45)(H,39,43)(H,40,44)(H4,35,36,37)/t23-,24-,25+,26-/m0/s1 VDYDFOLHCMWLDM-SSUZURRFSA-N 85734 H-Hmt-D-Arg-Phe-Lys-NH2 I::H-Hmt-D-Arg-Phe-Lys-NH2 II::H-Mmt-D-Arg-Phe-Lys-NH2 Mu-type opioid receptor Cavia cutleri 0.222 PDSP Ki 10.1016/s0223-5234(00)01171-5 10.7270/Q23X856N 11121615 Schiller, PW; Nguyen, TM; Berezowska, I; Dupuis, S; Weltrowska, G; Chung, NN; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85734&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9809339 136351834 ZINC67961492 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 181520 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C32H37N5O5/c33-25(18-23-13-15-24(38)16-14-23)32(42)37-17-7-12-28(37)31(41)36-27(20-22-10-5-2-6-11-22)30(40)35-26(29(34)39)19-21-8-3-1-4-9-21/h1-6,8-11,13-16,25-28,38H,7,12,17-20,33H2,(H2,34,39)(H,35,40)(H,36,41)/t25-,26-,27-,28-/m0/s1 XIJHWXXXIMEHKW-LJWNLINESA-N 50139013 (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::(S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxamide::1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylicacid[1-((S)-(S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL333357::H-Tyr-Pro-Phe-Phe-NH2::Tyr-Pro-Phe-Phe-NH2::endomorphin-2 Mu-type opioid receptor Cavia cutleri 2.06 PDSP Ki 10.1016/s0223-5234(00)01171-5 10.7270/Q23X856N 11121615 Schiller, PW; Nguyen, TM; Berezowska, I; Dupuis, S; Weltrowska, G; Chung, NN; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139013&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311081 104029000 CHEMBL333357 3668 ZINC14951634 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 181521 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C28H37N5O7/c1-17(2)12-23(28(39)40)33-27(38)22(14-18-6-4-3-5-7-18)32-25(36)16-30-24(35)15-31-26(37)21(29)13-19-8-10-20(34)11-9-19/h3-11,17,21-23,34H,12-16,29H2,1-2H3,(H,30,35)(H,31,37)(H,32,36)(H,33,38)(H,39,40)/t21-,22-,23-/m0/s1 URLZCHNOLZSCCA-VABKMULXSA-N 50001465 (S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::([Leu]-enkephalin)2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::(enkephalin)2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-1-oxo-3-phenyl-propylamino]-4-methyl-pentanoic acid::2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::2-[1-[1-amino-2-(4-hydroxyphenyl)-(1S)-ethylcarboxamidomethylcarboxamidomethylcarboxamido]-2-phenyl-(1S)-ethylcarboxamido]-4-methyl-(2S)-pentanoic acid::2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid(Enkephalin)::2-{1-[1-amino-2-(4-hydroxyphenyl)ethylcarboxamidomethylcarboxamidomethylcarboxamido]-2-phenylethylcarboxamido}-4-methylpentanoic acid::CHEMBL8234::ENKEPHALIN::Leu-ENKEPHALIN::Leu5-Enkephalin::Tyr-Gly-Gly-Phe-Leu-OH Mu-type opioid receptor Cavia cutleri 9.43 PDSP Ki 10.1016/s0223-5234(00)01171-5 10.7270/Q23X856N 11121615 Schiller, PW; Nguyen, TM; Berezowska, I; Dupuis, S; Weltrowska, G; Chung, NN; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001465&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 461776 103915930 CHEMBL8234 ZINC14952116 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 181522 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 1 PDSP Ki 10.1016/s0223-5234(00)01171-5 10.7270/Q23X856N 11121615 Schiller, PW; Nguyen, TM; Berezowska, I; Dupuis, S; Weltrowska, G; Chung, NN; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 181523 CN[C@@H](Cc1c(C)cc(O)cc1C)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C33H51N9O5/c1-20-16-23(43)17-21(2)24(20)19-27(38-3)31(46)41-26(13-9-15-39-33(36)37)30(45)42-28(18-22-10-5-4-6-11-22)32(47)40-25(29(35)44)12-7-8-14-34/h4-6,10-11,16-17,25-28,38,43H,7-9,12-15,18-19,34H2,1-3H3,(H2,35,44)(H,40,47)(H,41,46)(H,42,45)(H4,36,37,39)/t25-,26+,27-,28-/m0/s1 QTVCRCBVZNGBRM-PUHABZHSSA-N 85732 Tmt-D-Arg-Phe-Lys-NH2 Mu-type opioid receptor Cavia cutleri 0.192 PDSP Ki 10.1016/s0223-5234(00)01171-5 10.7270/Q23X856N 11121615 Schiller, PW; Nguyen, TM; Berezowska, I; Dupuis, S; Weltrowska, G; Chung, NN; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85732 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85732&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9809761 136351832 ZINC67961494 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 181524 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C32H49N9O5/c1-19-15-22(42)16-20(2)23(19)18-24(34)29(44)40-26(12-8-14-38-32(36)37)30(45)41-27(17-21-9-4-3-5-10-21)31(46)39-25(28(35)43)11-6-7-13-33/h3-5,9-10,15-16,24-27,42H,6-8,11-14,17-18,33-34H2,1-2H3,(H2,35,43)(H,39,46)(H,40,44)(H,41,45)(H4,36,37,38)/t24-,25-,26+,27-/m0/s1 FIAKHZXVLBNZLW-NFGXINMFSA-N 85731 [Dmt1]DALDA Mu-type opioid receptor Cavia cutleri 0.143 PDSP Ki 10.1016/s0223-5234(00)01171-5 10.7270/Q23X856N 11121615 Schiller, PW; Nguyen, TM; Berezowska, I; Dupuis, S; Weltrowska, G; Chung, NN; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85731 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85731&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9809562 136351831 ZINC28470648 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 179556 CO[C@@]12CC[C@@]3(C[C@@H]1[C@@](C)(O)C(C)(C)C)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45 InChI=1S/C29H41NO4/c1-25(2,3)26(4,32)20-15-27-10-11-29(20,33-5)24-28(27)12-13-30(16-17-6-7-17)21(27)14-18-8-9-19(31)23(34-24)22(18)28/h8-9,17,20-21,24,31-32H,6-7,10-16H2,1-5H3/t20-,21-,24-,26-,27-,28+,29+/m1/s1 RMRJXGBAOAMLHD-AGMYMXDYSA-N 50028147 2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(14R)-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-16-yl]-3,3-dimethyl-2-butanol::2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(15S)-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-16-yl]-3,3-dimethyl-2-butanol(Buprenorphine)::BUPRENORPHINE::Buprenorphine(+)::Buprenorphine(-)::Buprenorphine2-(3-cyclopropylmethyl-11-hydroxy-15-methoxy-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-16-yl)-3,3-dimethyl-2-butanol(::CHEMBL560511 Mu-type opioid receptor Cavia cutleri 0.57 PDSP Ki 10.7270/Q2707ZZK 10565829 Traynor, JR; Guo, L; Coop, A; Lewis, JW; Woods, JH Loughborough University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028147 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028147&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9811785 103937516 CHEMBL560511 C08007 ZINC38156722 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 179605 C[C@@H](O)[C@H](NC(=O)[C@H]1NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC1(C)C)NC(=O)[C@H](N)Cc1ccccc1)[C@@H](C)O)C(N)=O InChI=1S/C51H69N13O11S2/c1-26(65)39(42(53)68)62-49(75)41-51(3,4)77-76-25-38(61-43(69)33(52)21-28-11-6-5-7-12-28)47(73)59-36(22-29-16-18-31(67)19-17-29)45(71)60-37(23-30-24-57-34-14-9-8-13-32(30)34)46(72)58-35(15-10-20-56-50(54)55)44(70)63-40(27(2)66)48(74)64-41/h5-9,11-14,16-19,24,26-27,33,35-41,57,65-67H,10,15,20-23,25,52H2,1-4H3,(H2,53,68)(H,58,72)(H,59,73)(H,60,71)(H,61,69)(H,62,75)(H,63,70)(H,64,74)(H4,54,55,56)/t26-,27-,33-,35+,36+,37-,38+,39+,40+,41-/m1/s1 OFMQLVRLOGHAJI-FGHAYEPSSA-N 50346948 CHEMBL1795717::CTAP-NH2 Mu-type opioid receptor Cavia cutleri 48.1 PDSP Ki 10.1016/s0014-2999(99)00610-x 10.7270/Q2TT4PJ9 10585536 Marki, A; Monory, K; Otvos, F; Toth, G; Krassnig, R; Schmidhammer, H; Traynor, JR; Roques, BP; Maldonado, R; Borsodi, A Hungarian Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346948&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10418702 136353634 CHEMBL1795717 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 179607 COc1cccc2CC3N(CC4CC4)CC[C@@]4(CC(=O)CC[C@@]34OC)c12 InChI=1S/C22H29NO3/c1-25-18-5-3-4-16-12-19-22(26-2)9-8-17(24)13-21(22,20(16)18)10-11-23(19)14-15-6-7-15/h3-5,15,19H,6-14H2,1-2H3/t19?,21-,22-/m1/s1 INUCRGMCKDQKNA-CEAUUGKZSA-N 50016847 CHEMBL337041::Cyprodime Mu-type opioid receptor Cavia cutleri 26.6 PDSP Ki 10.1016/s0014-2999(99)00610-x 10.7270/Q2TT4PJ9 10585536 Marki, A; Monory, K; Otvos, F; Toth, G; Krassnig, R; Schmidhammer, H; Traynor, JR; Roques, BP; Maldonado, R; Borsodi, A Hungarian Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016847&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9975501 103928196 CHEMBL337041 ZINC13580323 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 179610 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C)[C@@H](Cc1ccccc1)C(=O)NCCO InChI=1S/C26H35N5O6/c1-17(30-25(36)21(27)14-19-8-10-20(33)11-9-19)24(35)29-16-23(34)31(2)22(26(37)28-12-13-32)15-18-6-4-3-5-7-18/h3-11,17,21-22,32-33H,12-16,27H2,1-2H3,(H,28,37)(H,29,35)(H,30,36)/t17-,21+,22+/m1/s1 HPZJMUBDEAMBFI-WTNAPCKOSA-N 21015 (2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]-N-methylacetamido}-N-(2-hydroxyethyl)-3-phenylpropanamide::2-Ala-4-MePhe-5-Gly-Enkephalin::CHEMBL38874::D-Ala2-MePhe4-Met(0)5-enkephalin-ol::DAMGO::RX 783006::US11492374, ID 2::[3H]DAMGO::[tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephalin Mu-type opioid receptor Cavia cutleri 2.6 PDSP Ki 10.1016/s0014-2999(99)00610-x 10.7270/Q2TT4PJ9 10585536 Marki, A; Monory, K; Otvos, F; Toth, G; Krassnig, R; Schmidhammer, H; Traynor, JR; Roques, BP; Maldonado, R; Borsodi, A Hungarian Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21015&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5462471 49689088 CHEMBL38874 1647 C04080 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 179612 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1C3CC[C@@H]4O)ccc5O InChI=1S/C17H21NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2,4,10-11,13,16,19-20H,3,5-8H2,1H3/t10?,11-,13+,16+,17+/m1/s1 IJVCSMSMFSCRME-OONJBDFYSA-N 50021325 4-methyl-(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-triene-10,14-diol(DHM)::CHEMBL1281::DIHYDROMORPHINE Mu-type opioid receptor Cavia cutleri 6 PDSP Ki 10.1016/s0014-2999(99)00610-x 10.7270/Q2TT4PJ9 10585536 Marki, A; Monory, K; Otvos, F; Toth, G; Krassnig, R; Schmidhammer, H; Traynor, JR; Roques, BP; Maldonado, R; Borsodi, A Hungarian Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021325&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25126776 103932033 CHEMBL1281 ZINC27625757 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 183603 C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)C(N)=O InChI=1S/C19H26N2O/c1-12-17-10-14-5-6-15(18(20)22)9-16(14)19(12,2)7-8-21(17)11-13-3-4-13/h5-6,9,12-13,17H,3-4,7-8,10-11H2,1-2H3,(H2,20,22)/t12-,17?,19-/m0/s1 FAVQVALXVLMHLE-BKBNBNODSA-N 50097579 (6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid amide::8-CAC::8-carboxamidocyclazocine::CHEMBL58646::US9656961, Example 00157 Mu-type opioid receptor Cavia cutleri 0.34 PDSP Ki 10.1124/jpet.302.1.374 10.7270/Q2959G3P 12065740 Bidlack, JM; Cohen, DJ; McLaughlin, JP; Lou, R; Ye, Y; Wentland, MP University of Rochester http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097579 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097579&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10086063 103994787 CHEMBL58646 ZINC29411253 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 183604 C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C18H25NO/c1-12-17-9-14-5-6-15(20)10-16(14)18(12,2)7-8-19(17)11-13-3-4-13/h5-6,10,12-13,17,20H,3-4,7-9,11H2,1-2H3/t12-,17+,18+/m1/s1 YQYVFVRQLZMJKJ-UUWFMWQGSA-N 50001022 (2S,6S,11S)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::(SSS)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyclo[9.1.1.0*3,8*]trideca-3(8),4,6-trien-6-ol(cyclazocine)::3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL293349::CYCLAZOCINE (-)::Cyclazocine::Cyclazocine (+) Mu-type opioid receptor Cavia cutleri 0.32 PDSP Ki 10.1124/jpet.302.1.374 10.7270/Q2959G3P 12065740 Bidlack, JM; Cohen, DJ; McLaughlin, JP; Lou, R; Ye, Y; Wentland, MP University of Rochester http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001022 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001022&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603759 103915555 CHEMBL293349 ZINC07996837 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 183605 CN(C1CCCC[C@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C19H26Cl2N2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17?,18-/m1/s1 VQLPLYSROCPWFF-QRWMCTBCSA-N 50169774 2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide; compound with methanesulfonic acid::CHEMBL360943::U-50488H::U50,488H Mu-type opioid receptor Cavia cutleri 220 PDSP Ki 10.1124/jpet.302.1.374 10.7270/Q2959G3P 12065740 Bidlack, JM; Cohen, DJ; McLaughlin, JP; Lou, R; Ye, Y; Wentland, MP University of Rochester http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50169774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50169774&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 68616 104054543 CHEMBL360943 C11796 ZINC00643032 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50001715 CC(C)[C@H](NC(=O)[C@H]1CSSC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](CC(O)=O)C(=O)N1)C(=O)NCC(N)=O InChI=1S/C35H46N8O10S2/c1-18(2)29(35(53)38-15-27(37)45)43-34(52)26-17-55-54-16-25(41-30(48)22(36)12-20-8-10-21(44)11-9-20)33(51)39-23(13-19-6-4-3-5-7-19)31(49)40-24(14-28(46)47)32(50)42-26/h3-11,18,22-26,29,44H,12-17,36H2,1-2H3,(H2,37,45)(H,38,53)(H,39,51)(H,40,49)(H,41,48)(H,42,50)(H,43,52)(H,46,47)/t22-,23-,24+,25-,26+,29-/m0/s1 YOZBAOXLTILTGR-PXIRGPTDSA-N 50280456 CHEMBL153466::{(4S,7R,10S,13R)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-10-benzyl-4-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradec-7-yl}-acetic acid Mu-type opioid receptor Cavia cutleri 3 ChEMBL 10.1016/S0960-894X(01)81195-1 10.7270/Q23R0STD Misicka, A; Nikiforovich, G; Lipkowski, AW; Horvath, R; Davis, P; Kramer, TH; Yamamura, HI; Hruby, VJ TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280456&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44367780 104122160 CHEMBL153466 ZINC95605937 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50001718 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C37H52N8O10/c1-19(2)30(36(54)40-18-28(39)47)45-37(55)31(20(3)4)44-35(53)27(17-29(48)49)43-34(52)26(16-22-9-7-6-8-10-22)42-32(50)21(5)41-33(51)25(38)15-23-11-13-24(46)14-12-23/h6-14,19-21,25-27,30-31,46H,15-18,38H2,1-5H3,(H2,39,47)(H,40,54)(H,41,51)(H,42,50)(H,43,52)(H,44,53)(H,45,55)(H,48,49)/t21-,25+,26+,27+,30+,31+/m1/s1 CJAORFIPPWIGPG-QXYJMILXSA-N 50001468 (S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::3-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL317956::H-Tyr-D-Ala-Phe-Asp-Val-Val-Gly-NH2::deltorphin C Mu-type opioid receptor Cavia cutleri 2.9 ChEMBL 10.1016/S0960-894X(01)81195-1 10.7270/Q23R0STD Misicka, A; Nikiforovich, G; Lipkowski, AW; Horvath, R; Davis, P; Kramer, TH; Yamamura, HI; Hruby, VJ TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001468&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10055958 103915933 CHEMBL317956 C18097 ZINC95610551 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50003914 COc1cccc2CC3N(CCc4ccccc4)CC[C@@]4(CC(=O)CC[C@@]34OC)c12 InChI=1S/C26H31NO3/c1-29-22-10-6-9-20-17-23-26(30-2)13-11-21(28)18-25(26,24(20)22)14-16-27(23)15-12-19-7-4-3-5-8-19/h3-10,23H,11-18H2,1-2H3/t23?,25-,26-/m1/s1 NWFRYEOZMKEEMS-NYJWAPBASA-N 50285003 3,10-dimethoxy-17-phenethyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-13-one; with HBr::CHEMBL545208 Mu-type opioid receptor Cavia cutleri 0.900000 ChEMBL 10.1016/0960-894X(95)00325-N 10.7270/Q2FX79XF Schmidhammer, H; Stangl, A; Furst, Z; Szabo, E; Borsodi, A; Patel, D; Traynor, JR TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50285003 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50285003&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10431410 104126574 CHEMBL545208 ZINC29560164 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50003917 COc1cccc2C[C@H]3N(C)CC[C@@]4(CC(=O)CC[C@@]34OC)c12 InChI=1S/C19H25NO3/c1-20-10-9-18-12-14(21)7-8-19(18,23-3)16(20)11-13-5-4-6-15(22-2)17(13)18/h4-6,16H,7-12H2,1-3H3/t16-,18-,19-/m1/s1 FXPIRWWMNVRGSD-BHIYHBOVSA-N 50326659 3,10-dimethoxy-17-methyl-(10S)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-13-one::3,10-dimethoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-13-one::CHEMBL606644 Mu-type opioid receptor Cavia cutleri 0.700000 ChEMBL 10.1016/0960-894X(95)00325-N 10.7270/Q2FX79XF Schmidhammer, H; Stangl, A; Furst, Z; Szabo, E; Borsodi, A; Patel, D; Traynor, JR TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326659 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326659&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 13559317 123105774 CHEMBL606644 ZINC29330780 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50003920 COc1cccc2C[C@H]3N(CC4CC4)CC[C@@]4(CC(=O)CC[C@@]34OC)c12 InChI=1S/C22H29NO3/c1-25-18-5-3-4-16-12-19-22(26-2)9-8-17(24)13-21(22,20(16)18)10-11-23(19)14-15-6-7-15/h3-5,15,19H,6-14H2,1-2H3/t19-,21-,22-/m1/s1 INUCRGMCKDQKNA-CEMLEFRQSA-N 50148071 (-)-N-(Cycloproylmethyl)-4,14-dimethoxymorphinan-6-one(Cyprodime)::17-cyclopropylmethyl-10-hydroxy-4,14-dimethoxy-(1S,9R,10S)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3-dien-6-one(cyprodime)::17-cyclopropylmethyl-3,10-dimethoxy-(1R,9R,10S)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-13-one::CHEMBL322796::CYPRODIME BROMIDE::Naltrindole analogue::cyprodime Mu-type opioid receptor Cavia cutleri 24 ChEMBL 10.1016/0960-894X(95)00325-N 10.7270/Q2FX79XF Schmidhammer, H; Stangl, A; Furst, Z; Szabo, E; Borsodi, A; Patel, D; Traynor, JR TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50148071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50148071&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5748293 104036454 CHEMBL322796 ZINC13580323 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50001989 CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)C12CC3CC(CC(C3)C1)C2)C(=O)N[C@@H](CC(C)C)C(O)=O InChI=1S/C43H66N6O8/c1-5-26(4)36(39(53)46-34(41(55)56)17-25(2)3)48-37(51)33(21-27-11-13-31(50)14-12-27)45-38(52)35-10-8-16-49(35)40(54)32(9-6-7-15-44)47-42(57)43-22-28-18-29(23-43)20-30(19-28)24-43/h11-14,25-26,28-30,32-36,50H,5-10,15-24,44H2,1-4H3,(H,45,52)(H,46,53)(H,47,57)(H,48,51)(H,55,56)/t26-,28?,29?,30?,32-,33-,34-,35-,36-,43?/m0/s1 UIMKLZHPVRXKRP-UBFYEMQFSA-N 50281811 (S)-2-{(2S,3S)-2-[(S)-2-[((S)-1-{(S)-2-[(Adamantane-1-carbonyl)-amino]-6-amino-hexanoyl}-pyrrolidine-2-carbonyl)-amino]-3-(4-hydroxy-phenyl)-propionylamino]-3-methyl-pentanoylamino}-4-methyl-pentanoic acid::CHEMBL2372106 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1016/S0960-894X(01)81014-3 10.7270/Q2M045XW Cain, GA; Christos, TE; Johnson, AL; Pottorf, RS; Confalone, PN; William Tam, S; Schmidt, WK TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281811 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281811&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10463024 104123485 CHEMBL2372106 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50003173 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5-c1ccsc1 InChI=1S/C21H21NO2S/c1-22-8-7-21-15-4-5-17(23)20(21)24-19-14(13-6-9-25-11-13)3-2-12(18(19)21)10-16(15)22/h2-6,9,11,15-17,20,23H,7-8,10H2,1H3/t15-,16+,17-,20-,21-/m0/s1 AQBOBFADHSBHCU-ZCZMFWIKSA-N 50283519 4-methyl-10-(3-thienyl)-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraen-14-ol::CHEMBL442709 Mu-type opioid receptor Cavia cutleri 3300 ChEMBL 10.1016/S0960-894X(01)80277-8 10.7270/Q2V124R0 Hedberg, MH; Johansson, AM; Fowler, CJ; Terenius, L; Hacksell, U TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50283519 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50283519&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44319000 104125176 CHEMBL442709 ZINC26506483 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50003175 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5-c1ccco1 InChI=1S/C21H21NO3/c1-22-9-8-21-14-6-7-16(23)20(21)25-19-13(17-3-2-10-24-17)5-4-12(18(19)21)11-15(14)22/h2-7,10,14-16,20,23H,8-9,11H2,1H3/t14-,15+,16-,20-,21-/m0/s1 PMCBOIGZSINBJD-OBRACTJBSA-N 50283521 10-(2-furyl)-4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraen-14-ol::CHEMBL84484 Mu-type opioid receptor Cavia cutleri 2600 ChEMBL 10.1016/S0960-894X(01)80277-8 10.7270/Q2V124R0 Hedberg, MH; Johansson, AM; Fowler, CJ; Terenius, L; Hacksell, U TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50283521 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50283521&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44319001 104125178 CHEMBL84484 ZINC26506488 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50003176 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5C(C)=O InChI=1S/C19H21NO3/c1-10(21)12-4-3-11-9-14-13-5-6-15(22)18-19(13,7-8-20(14)2)16(11)17(12)23-18/h3-6,13-15,18,22H,7-9H2,1-2H3/t13-,14+,15-,18-,19-/m0/s1 GIHASMBCZZCZMC-HZMZCJTDSA-N 50283516 1-[14-hydroxy-4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraen-10-yl]-1-ethanone::CHEMBL82576 Mu-type opioid receptor Cavia cutleri 640 ChEMBL 10.1016/S0960-894X(01)80277-8 10.7270/Q2V124R0 Hedberg, MH; Johansson, AM; Fowler, CJ; Terenius, L; Hacksell, U TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50283516 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50283516&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44319002 104125173 CHEMBL82576 ZINC26506493 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50003182 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5OS(=O)(=O)C(F)(F)F InChI=1S/C18H18F3NO5S/c1-22-7-6-17-10-3-4-12(23)16(17)26-15-13(27-28(24,25)18(19,20)21)5-2-9(14(15)17)8-11(10)22/h2-5,10-12,16,23H,6-8H2,1H3/t10-,11+,12-,16-,17-/m0/s1 BDSVSSUCVRQXEW-KOFBORESSA-N 50283518 14-hydroxy-4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraen-10-yl trifluoromethanesulfonate::CHEMBL440694 Mu-type opioid receptor Cavia cutleri 6400 ChEMBL 10.1016/S0960-894X(01)80277-8 10.7270/Q2V124R0 Hedberg, MH; Johansson, AM; Fowler, CJ; Terenius, L; Hacksell, U TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50283518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50283518&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15677950 104125175 CHEMBL440694 ZINC36221967 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50003183 CN1CC[C@]23[C@H]4Oc5cccc(C[C@@H]1[C@@H]2C=C[C@@H]4O)c35 InChI=1S/C17H19NO2/c1-18-8-7-17-11-5-6-13(19)16(17)20-14-4-2-3-10(15(14)17)9-12(11)18/h2-6,11-13,16,19H,7-9H2,1H3/t11-,12+,13-,16-,17-/m0/s1 MKMUIMIVJSNWCJ-ZWRJDUBHSA-N 50283522 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraen-14-ol::CHEMBL85457 Mu-type opioid receptor Cavia cutleri 530 ChEMBL 10.1016/S0960-894X(01)80277-8 10.7270/Q2V124R0 Hedberg, MH; Johansson, AM; Fowler, CJ; Terenius, L; Hacksell, U TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50283522 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50283522&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15677953 104125179 CHEMBL85457 ZINC26566774 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50003185 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 8.5 ChEMBL 10.1016/S0960-894X(01)80277-8 10.7270/Q2V124R0 Hedberg, MH; Johansson, AM; Fowler, CJ; Terenius, L; Hacksell, U TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50003187 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5-c1ccoc1 InChI=1S/C21H21NO3/c1-22-8-7-21-15-4-5-17(23)20(21)25-19-14(13-6-9-24-11-13)3-2-12(18(19)21)10-16(15)22/h2-6,9,11,15-17,20,23H,7-8,10H2,1H3/t15-,16+,17-,20-,21-/m0/s1 WPMZRKCFTBNYRK-ZCZMFWIKSA-N 50283517 10-(3-furyl)-4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraen-14-ol::CHEMBL87247 Mu-type opioid receptor Cavia cutleri 200 ChEMBL 10.1016/S0960-894X(01)80277-8 10.7270/Q2V124R0 Hedberg, MH; Johansson, AM; Fowler, CJ; Terenius, L; Hacksell, U TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50283517 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50283517&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44318784 104125174 CHEMBL87247 ZINC26574421 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50003188 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5C InChI=1S/C18H21NO2/c1-10-3-4-11-9-13-12-5-6-14(20)17-18(12,7-8-19(13)2)15(11)16(10)21-17/h3-6,12-14,17,20H,7-9H2,1-2H3/t12-,13+,14-,17-,18-/m0/s1 IBGSIGRPLGVTPB-UKCJKJFHSA-N 50283523 4,10-dimethyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraen-14-ol::CHEMBL85089 Mu-type opioid receptor Cavia cutleri 4500 ChEMBL 10.1016/S0960-894X(01)80277-8 10.7270/Q2V124R0 Hedberg, MH; Johansson, AM; Fowler, CJ; Terenius, L; Hacksell, U TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50283523 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50283523&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15677952 104125180 CHEMBL85089 ZINC26569212 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50002334 CC(C)[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](CCC(=O)NCCCC[C@H](NC1=O)C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C InChI=1S/C41H59N9O9/c1-23(2)34-40(58)47-29(36(43)54)12-8-9-19-44-32(52)18-17-30(38(56)49-35(24(3)4)41(59)50-34)48-39(57)31(21-25-10-6-5-7-11-25)46-33(53)22-45-37(55)28(42)20-26-13-15-27(51)16-14-26/h5-7,10-11,13-16,23-24,28-31,34-35,51H,8-9,12,17-22,42H2,1-4H3,(H2,43,54)(H,44,52)(H,45,55)(H,46,53)(H,47,58)(H,48,57)(H,49,56)(H,50,59)/t28-,29-,30+,31-,34-,35+/m0/s1 FYZAGLMEHOJAIB-AVLNBOPFSA-N 50001457 17-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-3-phenyl-propionylamino)-2,5-diisopropyl-3,6,14,18-tetraoxo-1,4,7,13tetraaza-cyclooctadecane-8-carboxylic acid amide::CHEMBL338985 Mu-type opioid receptor Cavia cutleri 3880 ChEMBL 10.1021/jm00099a025 10.7270/Q2H70DRH 1331451 Schiller, PW; Weltrowska, G; Nguyen, TM; Wilkes, BC; Chung, NN; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001457 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001457&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44351748 103915922 CHEMBL338985 ZINC95611420 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50002343 CSCC[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(N)=O InChI=1S/C44H62N10O10S2/c1-25(2)18-34(42(62)50-32(15-17-66-4)40(60)51-33(38(46)58)22-37(56)57)52-44(64)36(21-28-23-47-24-48-28)54-43(63)35(20-26-8-6-5-7-9-26)53-41(61)31(14-16-65-3)49-39(59)30(45)19-27-10-12-29(55)13-11-27/h5-13,23-25,30-36,55H,14-22,45H2,1-4H3,(H2,46,58)(H,47,48)(H,49,59)(H,50,62)(H,51,60)(H,52,64)(H,53,61)(H,54,63)(H,56,57)/t30-,31+,32-,33-,34-,35-,36-/m0/s1 BHSURCCZOBVHJJ-NWOHMYAQSA-N 50000518 3-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyrylamino}-3-phenyl-propionylamino)-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-4-methylsulfanyl-butyrylamino)-succinamic acid::3-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyrylamino}-3-phenyl-propionylamino)-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-4-methylsulfanyl-butyrylamino)-succinamic acid (deltorphin A)::CHEMBL20775 Mu-type opioid receptor Cavia cutleri 281 ChEMBL 10.1021/jm00099a025 10.7270/Q2H70DRH 1331451 Schiller, PW; Weltrowska, G; Nguyen, TM; Wilkes, BC; Chung, NN; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000518&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3035060 103915066 CHEMBL20775 C18010 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50002367 CCCC[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCC)C(=O)N[C@@H](CC(O)=O)C(N)=O InChI=1S/C46H66N10O10/c1-5-7-14-33(51-41(61)32(47)21-29-16-18-31(57)19-17-29)43(63)55-37(22-28-12-10-9-11-13-28)45(65)56-38(23-30-25-49-26-50-30)46(66)54-36(20-27(3)4)44(64)52-34(15-8-6-2)42(62)53-35(40(48)60)24-39(58)59/h9-13,16-19,25-27,32-38,57H,5-8,14-15,20-24,47H2,1-4H3,(H2,48,60)(H,49,50)(H,51,61)(H,52,64)(H,53,62)(H,54,66)(H,55,63)(H,56,65)(H,58,59)/t32-,33+,34-,35-,36-,37-,38-/m0/s1 HCGVYWATRUEXKG-GDFXEKLASA-N 50001456 3-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-hexanoylamino}-3-phenyl-propionylamino)-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-hexanoylamino)-succinamic acid::CHEMBL436590 Mu-type opioid receptor Cavia cutleri 241 ChEMBL 10.1021/jm00099a025 10.7270/Q2H70DRH 1331451 Schiller, PW; Weltrowska, G; Nguyen, TM; Wilkes, BC; Chung, NN; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001456&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10328441 103915921 CHEMBL436590 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50004580 COC12C=CC34C[C@@]1(C)C(=N[C@H]2C31CCN(C)C4Cc2ccc(O)cc12)c1ccccc1 InChI=1S/C28H30N2O2/c1-25-17-26-11-12-28(25,32-3)24(29-23(25)18-7-5-4-6-8-18)27(26)13-14-30(2)22(26)15-19-9-10-20(31)16-21(19)27/h4-12,16,22,24,31H,13-15,17H2,1-3H3/t22?,24-,25-,26?,27?,28?/m0/s1 DIWFHEYPDQRWTR-IRLVDXFISA-N 50286103 CHEMBL102092::Morphinan Cyclic Imine analogue Mu-type opioid receptor Cavia cutleri 0.330000 ChEMBL 10.1016/0960-894X(95)00522-1 10.7270/Q24F1QQT Husbands, SM; Lewis, JW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286103 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286103&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44331854 104127674 CHEMBL102092 ZINC26745696 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50004581 CO[C@]12C=C[C@]34C[C@@]1(C)[C@@H](N(C)[C@H]2C31CCN(C)C4Cc2ccc(O)cc12)c1ccccc1 InChI=1S/C29H34N2O2/c1-26-18-27-12-13-29(26,33-4)25(31(3)24(26)19-8-6-5-7-9-19)28(27)14-15-30(2)23(27)16-20-10-11-21(32)17-22(20)28/h5-13,17,23-25,32H,14-16,18H2,1-4H3/t23?,24-,25-,26-,27+,28?,29-/m0/s1 VAZGOUQKUKGVDX-GRHZWHQTSA-N 50286105 CHEMBL318636::Morphinan Cyclic Imine analogue Mu-type opioid receptor Cavia cutleri 0.360000 ChEMBL 10.1016/0960-894X(95)00522-1 10.7270/Q24F1QQT Husbands, SM; Lewis, JW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286105 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286105&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44331873 104127676 CHEMBL318636 ZINC26816833 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50004585 CCOc1ccc(cc1)C1=N[C@@H]2[C@@]3(OC)C=C[C@@]4(C[C@@]13C)C1Cc3ccc(OC)c(O)c3C24CCN1C InChI=1S/C31H36N2O4/c1-6-37-21-10-7-19(8-11-21)26-28(2)18-29-13-14-31(28,36-5)27(32-26)30(29)15-16-33(3)23(29)17-20-9-12-22(35-4)25(34)24(20)30/h7-14,23,27,34H,6,15-18H2,1-5H3/t23?,27-,28-,29+,30?,31-/m0/s1 UBHZAZPYIIUMET-GEVOMTDJSA-N 50286102 CHEMBL353736::Morphinan Cyclic Imine analogue Mu-type opioid receptor Cavia cutleri 0.890000 ChEMBL 10.1016/0960-894X(95)00522-1 10.7270/Q24F1QQT Husbands, SM; Lewis, JW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286102 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286102&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44386782 104127673 CHEMBL353736 ZINC36221415 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50004586 COC12C=CC34C[C@@]1(C)[C@@H](N[C@H]2C31CCN(C)C4Cc2ccc(O)cc12)c1ccccc1 InChI=1S/C28H32N2O2/c1-25-17-26-11-12-28(25,32-3)24(29-23(25)18-7-5-4-6-8-18)27(26)13-14-30(2)22(26)15-19-9-10-20(31)16-21(19)27/h4-12,16,22-24,29,31H,13-15,17H2,1-3H3/t22?,23-,24-,25-,26?,27?,28?/m0/s1 RGJHUVJQGAAZLK-KKVBBDEKSA-N 50286106 CHEMBL321570::Morphinan Cyclic Imine analogue Mu-type opioid receptor Cavia cutleri 0.150000 ChEMBL 10.1016/0960-894X(95)00522-1 10.7270/Q24F1QQT Husbands, SM; Lewis, JW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286106 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286106&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44331862 104127677 CHEMBL321570 ZINC26746348 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50004589 COc1ccc2CC3N(C)CCC4([C@@H]5N=C(c6ccccc6)[C@]6(C)CC34C=CC56OC)c2c1O InChI=1S/C29H32N2O3/c1-26-17-27-12-13-29(26,34-4)25(30-24(26)18-8-6-5-7-9-18)28(27)14-15-31(2)21(27)16-19-10-11-20(33-3)23(32)22(19)28/h5-13,21,25,32H,14-17H2,1-4H3/t21?,25-,26-,27?,28?,29?/m0/s1 ZRGVFUGLXNQEIK-GKGBAPQUSA-N 50286104 CHEMBL410909::Morphinan Cyclic Imine analogue Mu-type opioid receptor Cavia cutleri 0.250000 ChEMBL 10.1016/0960-894X(95)00522-1 10.7270/Q24F1QQT Husbands, SM; Lewis, JW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286104 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286104&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44331831 104127675 CHEMBL410909 ZINC36221191 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50004592 [I-].COc1ccc2C[C@@H]3[C@]45C[C@@]6(C)C(=N[C@H]([C@@]6(OC)C=C4)[C@]5(CC[N+]3(C)C)c2c1OC)c1ccccc1 InChI=1S/C31H37N2O3.HI/c1-28-19-29-14-15-31(28,36-6)27(32-26(28)20-10-8-7-9-11-20)30(29)16-17-33(2,3)23(29)18-21-12-13-22(34-4)25(35-5)24(21)30;/h7-15,23,27H,16-19H2,1-6H3;1H/q+1;/p-1/t23-,27+,28+,29-,30+,31+;/m1./s1 YTLUPTQMEWWZIA-CKIJOASCSA-M 50286101 CHEMBL3037845::Morphinan Cyclic Imine analogue Mu-type opioid receptor Cavia cutleri 0.560000 ChEMBL 10.1016/0960-894X(95)00522-1 10.7270/Q24F1QQT Husbands, SM; Lewis, JW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286101&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73355784 104127672 CHEMBL3037845 ZINC43120378 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50003634 CCC(=O)N1C2CCN(CCc3ccccc3)C[C@H]2COc2ccccc12 InChI=1S/C23H28N2O2/c1-2-23(26)25-20-13-15-24(14-12-18-8-4-3-5-9-18)16-19(20)17-27-22-11-7-6-10-21(22)25/h3-11,19-20H,2,12-17H2,1H3/t19-,20?/m0/s1 XJZCYMONKQXDLC-XJDOXCRVSA-N 50450285 CHEMBL2079638 Mu-type opioid receptor Cavia cutleri 5.1 ChEMBL 10.1016/0960-894X(95)00190-5 10.7270/Q2513Z5G Kudzma, LV; Evans, SM; Turnbull, SP; Severnak, SA; Ezell, EF TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50450285 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50450285&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 70682644 225145040 CHEMBL2079638 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50003635 CCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 InChI=1S/C22H28N2O/c1-2-22(25)24(20-11-7-4-8-12-20)21-14-17-23(18-15-21)16-13-19-9-5-3-6-10-19/h3-12,21H,2,13-18H2,1H3 PJMPHNIQZUBGLI-UHFFFAOYSA-N 50008984 4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-phthalazin-1-one::CHEMBL596::Duragesic-100::Duragesic-12::Duragesic-25::Duragesic-50::Duragesic-75::FENTANYL::FENTANYL CITRATE::FENTANYL-HCl::Fentanyl-100::Fentanyl-12::Fentanyl-25::Fentanyl-50::Fentanyl-75::Fentora::Innovar::Ionsys::N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide::N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide(Fentanyl)::N-(1-phenethylpiperidin-4-yl)-N-phenylpropionamide Mu-type opioid receptor Cavia cutleri 3.1 ChEMBL 10.1016/0960-894X(95)00190-5 10.7270/Q2513Z5G Kudzma, LV; Evans, SM; Turnbull, SP; Severnak, SA; Ezell, EF TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008984&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 7V7 5TZO,8EF5,7U64 3345 103922051 119915 CHEMBL596 DB00813 1626 ZINC02522669 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50003637 CCC(=O)N1C2CCN(CCc3ccccc3)C[C@@H]2COc2ccccc12 InChI=1S/C23H28N2O2/c1-2-23(26)25-20-13-15-24(14-12-18-8-4-3-5-9-18)16-19(20)17-27-22-11-7-6-10-21(22)25/h3-11,19-20H,2,12-17H2,1H3/t19-,20?/m1/s1 XJZCYMONKQXDLC-FIWHBWSRSA-N 50450284 CHEMBL2079569 Mu-type opioid receptor Cavia cutleri 5.8 ChEMBL 10.1016/0960-894X(95)00190-5 10.7270/Q2513Z5G Kudzma, LV; Evans, SM; Turnbull, SP; Severnak, SA; Ezell, EF TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50450284 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50450284&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 70695247 225145039 CHEMBL2079569 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50008528 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1 DQCKKXVULJGBQN-XFWGSAIBSA-N 60212 (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::MLS000069607::NALTREXONE HYDROCHLORIDE::SMR000058767::US10988481, Compound NTX::US9107954, naltrexone::cid_5485201 Mu-type opioid receptor Cavia cutleri 0.560000 ChEMBL 10.1016/s0960-894x(98)00576-9 10.7270/Q2S75FGQ 9873693 Thomas, JB; Mascarella, SW; Burgess, JP; Xu, H; McCullough, KB; Rothman, RB; Flippen-Anderson, JL; George, CF; Cantrell, BE; Zimmerman, DM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60212&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5360515 252639834 DB00704 C07253 ZINC00001773 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50008520 C[C@H]1CN(CCc2ccccc2)CC[C@@]1(C)c1cccc(O)c1 InChI=1S/C21H27NO/c1-17-16-22(13-11-18-7-4-3-5-8-18)14-12-21(17,2)19-9-6-10-20(23)15-19/h3-10,15,17,23H,11-14,16H2,1-2H3/t17-,21+/m0/s1 ULOGPOOAAOSAOC-LAUBAEHRSA-N 50045767 (+)-N-phenethyl trans-3(R),4(R)-dimethyl-4-(3-hydroxyphenyl)piperidine::3-((3R,4R)-3,4-Dimethyl-1-phenethyl-piperidin-4-yl)-phenol::3-(3,4-Dimethyl-1-phenethyl-piperidin-4-yl)-phenol::3-(trans-3,4-dimethyl-1-phenethylpiperidin-4-yl)phenol::CHEMBL319536::N-phenethyltrans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidine Mu-type opioid receptor Cavia cutleri 1.5 ChEMBL 10.1016/s0960-894x(98)00576-9 10.7270/Q2S75FGQ 9873693 Thomas, JB; Mascarella, SW; Burgess, JP; Xu, H; McCullough, KB; Rothman, RB; Flippen-Anderson, JL; George, CF; Cantrell, BE; Zimmerman, DM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045767 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045767&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 134131 103976640 CHEMBL319536 ZINC06037805 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50008521 C[C@@]12CN(CCc3ccccc3)CC[C@@]1(Cc1ccccc1C2)c1cccc(O)c1 InChI=1S/C28H31NO/c1-27-19-23-10-5-6-11-24(23)20-28(27,25-12-7-13-26(30)18-25)15-17-29(21-27)16-14-22-8-3-2-4-9-22/h2-13,18,30H,14-17,19-21H2,1H3/t27-,28-/m1/s1 ITGNKLZJCRMFGA-VSGBNLITSA-N 50072452 3-((4aS,10aS)-10a-Methyl-2-phenethyl-1,3,4,5,10,10a-hexahydro-2H-benzo[g]isoquinolin-4a-yl)-phenol::CHEMBL107398 Mu-type opioid receptor Cavia cutleri 10 ChEMBL 10.1016/s0960-894x(98)00576-9 10.7270/Q2S75FGQ 9873693 Thomas, JB; Mascarella, SW; Burgess, JP; Xu, H; McCullough, KB; Rothman, RB; Flippen-Anderson, JL; George, CF; Cantrell, BE; Zimmerman, DM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072452 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072452&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9843770 103966080 CHEMBL107398 ZINC26842794 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50008527 CN1CC[C@@]2(Cc3ccccc3C[C@]2(C)C1)c1cccc(O)c1 InChI=1S/C21H25NO/c1-20-13-16-6-3-4-7-17(16)14-21(20,10-11-22(2)15-20)18-8-5-9-19(23)12-18/h3-9,12,23H,10-11,13-15H2,1-2H3/t20-,21-/m1/s1 POUJDAQKDOGDRQ-NHCUHLMSSA-N 50072453 3-((4aS,10aS)-2,10a-Dimethyl-1,3,4,5,10,10a-hexahydro-2H-benzo[g]isoquinolin-4a-yl)-phenol::CHEMBL324681 Mu-type opioid receptor Cavia cutleri 119 ChEMBL 10.1016/s0960-894x(98)00576-9 10.7270/Q2S75FGQ 9873693 Thomas, JB; Mascarella, SW; Burgess, JP; Xu, H; McCullough, KB; Rothman, RB; Flippen-Anderson, JL; George, CF; Cantrell, BE; Zimmerman, DM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072453&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9948520 103966081 CHEMBL324681 ZINC26942056 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50008530 C[C@H]1CN(C)CC[C@@]1(C)c1cccc(O)c1 InChI=1S/C14H21NO/c1-11-10-15(3)8-7-14(11,2)12-5-4-6-13(16)9-12/h4-6,9,11,16H,7-8,10H2,1-3H3/t11-,14+/m0/s1 XYCWBUDSPOTODB-SMDDNHRTSA-N 50045772 3-((3R,4R)-1,3,4-Trimethyl-piperidin-4-yl)-phenol::3-(1,3,4-Trimethyl-piperidin-4-yl)-phenol::CHEMBL318723 Mu-type opioid receptor Cavia cutleri 80 ChEMBL 10.1016/s0960-894x(98)00576-9 10.7270/Q2S75FGQ 9873693 Thomas, JB; Mascarella, SW; Burgess, JP; Xu, H; McCullough, KB; Rothman, RB; Flippen-Anderson, JL; George, CF; Cantrell, BE; Zimmerman, DM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045772 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045772&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 132913 103976645 CHEMBL318723 ZINC06037803 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50008535 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1 DQCKKXVULJGBQN-XFWGSAIBSA-N 60212 (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::MLS000069607::NALTREXONE HYDROCHLORIDE::SMR000058767::US10988481, Compound NTX::US9107954, naltrexone::cid_5485201 Mu-type opioid receptor Cavia cutleri 0.930000 ChEMBL 10.1016/s0960-894x(98)00576-9 10.7270/Q2S75FGQ 9873693 Thomas, JB; Mascarella, SW; Burgess, JP; Xu, H; McCullough, KB; Rothman, RB; Flippen-Anderson, JL; George, CF; Cantrell, BE; Zimmerman, DM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60212&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5360515 252639834 DB00704 C07253 ZINC00001773 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50007449 C[C@H]([C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(O)=O)c1c(C)cc(O)cc1C InChI=1S/C22H26N2O4/c1-12-8-17(25)9-13(2)19(12)14(3)20(23)21(26)24-11-16-7-5-4-6-15(16)10-18(24)22(27)28/h4-9,14,18,20,25H,10-11,23H2,1-3H3,(H,27,28)/t14-,18-,20-/m0/s1 FCXFTRJOTXZTEP-DCPHZVHLSA-N 50290892 (S)-2-[(2S,3S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-butyryl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid; hydrochloride::CHEMBL557027 Mu-type opioid receptor Cavia cutleri >80000 ChEMBL 10.1016/S0960-894X(97)10145-7 10.7270/Q2H13211 Liao, S; Lin, J; Shenderovich, MD; Han, Y; Hasohata, K; Davis, P; Qiu, W; Porreca, F; Yamamura, HI; Hruby, VJ TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290892 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290892&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44334445 104132444 CHEMBL557027 ZINC26819314 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50007451 C[C@@H]([C@@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(O)=O)c1c(C)cc(O)cc1C InChI=1S/C22H26N2O4/c1-12-8-17(25)9-13(2)19(12)14(3)20(23)21(26)24-11-16-7-5-4-6-15(16)10-18(24)22(27)28/h4-9,14,18,20,25H,10-11,23H2,1-3H3,(H,27,28)/t14-,18+,20-/m1/s1 FCXFTRJOTXZTEP-HEFCMCLBSA-N 50290891 (S)-2-[(2R,3R)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-butyryl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid; hydrochloride::CHEMBL540302 Mu-type opioid receptor Cavia cutleri >80000 ChEMBL 10.1016/S0960-894X(97)10145-7 10.7270/Q2H13211 Liao, S; Lin, J; Shenderovich, MD; Han, Y; Hasohata, K; Davis, P; Qiu, W; Porreca, F; Yamamura, HI; Hruby, VJ TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290891 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290891&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10251488 104132443 CHEMBL540302 ZINC26828991 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50007452 CC(C(NC(=O)OC(C)(C)C)C(=O)N1Cc2ccccc2C[C@H]1C(=O)OCc1ccccc1)c1c(C)cc(O)cc1C InChI=1S/C34H40N2O6/c1-21-16-27(37)17-22(2)29(21)23(3)30(35-33(40)42-34(4,5)6)31(38)36-19-26-15-11-10-14-25(26)18-28(36)32(39)41-20-24-12-8-7-9-13-24/h7-17,23,28,30,37H,18-20H2,1-6H3,(H,35,40)/t23?,28-,30?/m0/s1 GRLHRVKEPJNPBL-IGIYDSRNSA-N 50290890 (S)-2-[2-tert-Butoxycarbonylamino-3-(4-hydroxy-2,6-dimethyl-phenyl)-butyryl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid benzyl ester::CHEMBL104950 Mu-type opioid receptor Cavia cutleri 8400 ChEMBL 10.1016/S0960-894X(97)10145-7 10.7270/Q2H13211 Liao, S; Lin, J; Shenderovich, MD; Han, Y; Hasohata, K; Davis, P; Qiu, W; Porreca, F; Yamamura, HI; Hruby, VJ TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290890&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44334192 104132442 CHEMBL104950 ZINC26829012 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50007453 C[C@@H]([C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(O)=O)c1c(C)cc(O)cc1C InChI=1S/C22H26N2O4/c1-12-8-17(25)9-13(2)19(12)14(3)20(23)21(26)24-11-16-7-5-4-6-15(16)10-18(24)22(27)28/h4-9,14,18,20,25H,10-11,23H2,1-3H3,(H,27,28)/t14-,18+,20+/m1/s1 FCXFTRJOTXZTEP-WNYOCNMUSA-N 50290894 (S)-2-[(2S,3R)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-butyryl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid; hydrochloride::CHEMBL545269 Mu-type opioid receptor Cavia cutleri 35000 ChEMBL 10.1016/S0960-894X(97)10145-7 10.7270/Q2H13211 Liao, S; Lin, J; Shenderovich, MD; Han, Y; Hasohata, K; Davis, P; Qiu, W; Porreca, F; Yamamura, HI; Hruby, VJ TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290894 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290894&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44334179 104132446 CHEMBL545269 ZINC26829563 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50007454 N[C@@H](Cc1ccc(O)cc1)C(=O)N1Cc2ccccc2C[C@H]1C(O)=O InChI=1S/C19H20N2O4/c20-16(9-12-5-7-15(22)8-6-12)18(23)21-11-14-4-2-1-3-13(14)10-17(21)19(24)25/h1-8,16-17,22H,9-11,20H2,(H,24,25)/t16-,17-/m0/s1 VUOZTGVYOFFWCN-IRXDYDNUSA-N 50060080 2-({2-[(R)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-propionic acid::CHEMBL485576 Mu-type opioid receptor Cavia cutleri 28411 ChEMBL 10.1016/S0960-894X(97)10145-7 10.7270/Q2H13211 Liao, S; Lin, J; Shenderovich, MD; Han, Y; Hasohata, K; Davis, P; Qiu, W; Porreca, F; Yamamura, HI; Hruby, VJ TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060080&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44588783 103955852 CHEMBL485576 ZINC26831732 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50007455 C[C@H]([C@@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(O)=O)c1c(C)cc(O)cc1C InChI=1S/C22H26N2O4/c1-12-8-17(25)9-13(2)19(12)14(3)20(23)21(26)24-11-16-7-5-4-6-15(16)10-18(24)22(27)28/h4-9,14,18,20,25H,10-11,23H2,1-3H3,(H,27,28)/t14-,18-,20+/m0/s1 FCXFTRJOTXZTEP-ADLFWFRXSA-N 50290889 (S)-2-[(2R,3S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-butyryl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid; hydrochloride::CHEMBL545265 Mu-type opioid receptor Cavia cutleri >80000 ChEMBL 10.1016/S0960-894X(97)10145-7 10.7270/Q2H13211 Liao, S; Lin, J; Shenderovich, MD; Han, Y; Hasohata, K; Davis, P; Qiu, W; Porreca, F; Yamamura, HI; Hruby, VJ TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290889 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290889&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44334190 104132441 CHEMBL545265 ZINC26825023 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50008771 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C46H56N10O10/c1-27(51-43(63)35(47)21-31-13-17-33(57)18-14-31)41(61)49-25-39(59)53-37(23-29-9-5-3-6-10-29)45(65)55-56-46(66)38(24-30-11-7-4-8-12-30)54-40(60)26-50-42(62)28(2)52-44(64)36(48)22-32-15-19-34(58)20-16-32/h3-20,27-28,35-38,57-58H,21-26,47-48H2,1-2H3,(H,49,61)(H,50,62)(H,51,63)(H,52,64)(H,53,59)(H,54,60)(H,55,65)(H,56,66)/t27-,28+,35-,36-,37-,38-/m0/s1 DESSEGDLRYOPTJ-LWXVJZBWSA-N 50069558 2-Amino-N-((S)-1-{[(2-{N'-[2-(2-{(S)-2-[2-amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-acetylamino)-3-phenyl-propionyl]-hydrazino}-1-benzyl-2-oxo-ethylcarbamoyl)-methyl]-carbamoyl}-ethyl)-3-(4-hydroxy-phenyl)-propionamide::CHEMBL2371056 Mu-type opioid receptor Cavia cutleri 8.8 ChEMBL 10.1016/s0960-894x(98)00065-1 10.7270/Q2736Q17 9871617 Li, G; Haq, W; Xiang, L; Lou, BS; Hughes, R; De Leon, IA; Davis, P; Gillespie, TJ; Romanowski, M; Zhu, X; Misicka, A; Lipkowski, AW; Porreca, F; Davis, TP; Yamamura, HI; O'Brien, DF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069558&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 134377 103963618 CHEMBL2371056 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50008773 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1cccc2ccccc12)C(=O)NNC(=O)[C@H](Cc1cccc2ccccc12)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C54H60N10O10/c1-31(59-51(71)43(55)25-33-17-21-39(65)22-18-33)49(69)57-29-47(67)61-45(27-37-13-7-11-35-9-3-5-15-41(35)37)53(73)63-64-54(74)46(28-38-14-8-12-36-10-4-6-16-42(36)38)62-48(68)30-58-50(70)32(2)60-52(72)44(56)26-34-19-23-40(66)24-20-34/h3-24,31-32,43-46,65-66H,25-30,55-56H2,1-2H3,(H,57,69)(H,58,70)(H,59,71)(H,60,72)(H,61,67)(H,62,68)(H,63,73)(H,64,74)/t31-,32-,43+,44+,45+,46+/m1/s1 GLZFVTVMXOQFMT-ATTIMZMDSA-N 50069559 Biphalin Analogue::CHEMBL2371057 Mu-type opioid receptor Cavia cutleri 1.7 ChEMBL 10.1016/s0960-894x(98)00065-1 10.7270/Q2736Q17 9871617 Li, G; Haq, W; Xiang, L; Lou, BS; Hughes, R; De Leon, IA; Davis, P; Gillespie, TJ; Romanowski, M; Zhu, X; Misicka, A; Lipkowski, AW; Porreca, F; Davis, TP; Yamamura, HI; O'Brien, DF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069559 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069559&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9963195 103963619 CHEMBL2371057 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50008778 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H]([C@H](C)c1ccccc1)C(=O)NNC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)[C@H](C)c1ccccc1 InChI=1S/C48H60N10O10/c1-27(33-11-7-5-8-12-33)41(55-39(61)25-51-43(63)29(3)53-45(65)37(49)23-31-15-19-35(59)20-16-31)47(67)57-58-48(68)42(28(2)34-13-9-6-10-14-34)56-40(62)26-52-44(64)30(4)54-46(66)38(50)24-32-17-21-36(60)22-18-32/h5-22,27-30,37-38,41-42,59-60H,23-26,49-50H2,1-4H3,(H,51,63)(H,52,64)(H,53,65)(H,54,66)(H,55,61)(H,56,62)(H,57,67)(H,58,68)/t27-,28-,29-,30-,37+,38+,41+,42+/m1/s1 LBULAXFRDMUFHP-DYFNZJEASA-N 50069562 2-Amino-N-((S)-1-{[((R)-1-{N'-[(R)-2-(2-{(S)-2-[2-amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-acetylamino)-3-phenyl-butyryl]-hydrazinocarbonyl}-2-phenyl-propylcarbamoyl)-methyl]-carbamoyl}-ethyl)-3-(4-hydroxy-phenyl)-propionamide::CHEMBL2371082 Mu-type opioid receptor Cavia cutleri 21 ChEMBL 10.1016/s0960-894x(98)00065-1 10.7270/Q2736Q17 9871617 Li, G; Haq, W; Xiang, L; Lou, BS; Hughes, R; De Leon, IA; Davis, P; Gillespie, TJ; Romanowski, M; Zhu, X; Misicka, A; Lipkowski, AW; Porreca, F; Davis, TP; Yamamura, HI; O'Brien, DF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069562 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069562&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73354631 103963622 CHEMBL2371082 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50008779 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H]([C@@H](C)c1ccccc1)C(=O)NNC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)[C@@H](C)c1ccccc1 InChI=1S/C48H60N10O10/c1-27(33-11-7-5-8-12-33)41(55-39(61)25-51-43(63)29(3)53-45(65)37(49)23-31-15-19-35(59)20-16-31)47(67)57-58-48(68)42(28(2)34-13-9-6-10-14-34)56-40(62)26-52-44(64)30(4)54-46(66)38(50)24-32-17-21-36(60)22-18-32/h5-22,27-30,37-38,41-42,59-60H,23-26,49-50H2,1-4H3,(H,51,63)(H,52,64)(H,53,65)(H,54,66)(H,55,61)(H,56,62)(H,57,67)(H,58,68)/t27-,28-,29+,30+,37-,38-,41-,42-/m0/s1 LBULAXFRDMUFHP-SAUILYIYSA-N 50069561 2-Amino-N-((S)-1-{[((S)-1-{N'-[(S)-2-(2-{(S)-2-[2-amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-acetylamino)-3-phenyl-butyryl]-hydrazinocarbonyl}-2-phenyl-propylcarbamoyl)-methyl]-carbamoyl}-ethyl)-3-(4-hydroxy-phenyl)-propionamide::CHEMBL2371081 Mu-type opioid receptor Cavia cutleri 41 ChEMBL 10.1016/s0960-894x(98)00065-1 10.7270/Q2736Q17 9871617 Li, G; Haq, W; Xiang, L; Lou, BS; Hughes, R; De Leon, IA; Davis, P; Gillespie, TJ; Romanowski, M; Zhu, X; Misicka, A; Lipkowski, AW; Porreca, F; Davis, TP; Yamamura, HI; O'Brien, DF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069561 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069561&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73350143 103963621 CHEMBL2371081 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50008781 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1c(F)c(F)c(F)c(F)c1F)C(=O)NNC(=O)[C@H](Cc1c(F)c(F)c(F)c(F)c1F)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C46H46F10N10O10/c1-17(61-43(73)25(57)11-19-3-7-21(67)8-4-19)41(71)59-15-29(69)63-27(13-23-31(47)35(51)39(55)36(52)32(23)48)45(75)65-66-46(76)28(14-24-33(49)37(53)40(56)38(54)34(24)50)64-30(70)16-60-42(72)18(2)62-44(74)26(58)12-20-5-9-22(68)10-6-20/h3-10,17-18,25-28,67-68H,11-16,57-58H2,1-2H3,(H,59,71)(H,60,72)(H,61,73)(H,62,74)(H,63,69)(H,64,70)(H,65,75)(H,66,76)/t17-,18-,25+,26+,27+,28+/m1/s1 GCVFQGNOWGFECF-UWPALRQLSA-N 50069560 Biphalin Analogue::CHEMBL2371080 Mu-type opioid receptor Cavia cutleri 8.9 ChEMBL 10.1016/s0960-894x(98)00065-1 10.7270/Q2736Q17 9871617 Li, G; Haq, W; Xiang, L; Lou, BS; Hughes, R; De Leon, IA; Davis, P; Gillespie, TJ; Romanowski, M; Zhu, X; Misicka, A; Lipkowski, AW; Porreca, F; Davis, TP; Yamamura, HI; O'Brien, DF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069560 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069560&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73350142 103963620 CHEMBL2371080 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50008783 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)NNC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C54H60N10O10/c1-31(59-51(71)43(55)25-33-13-19-41(65)20-14-33)49(69)57-29-47(67)61-45(27-35-11-17-37-7-3-5-9-39(37)23-35)53(73)63-64-54(74)46(28-36-12-18-38-8-4-6-10-40(38)24-36)62-48(68)30-58-50(70)32(2)60-52(72)44(56)26-34-15-21-42(66)22-16-34/h3-24,31-32,43-46,65-66H,25-30,55-56H2,1-2H3,(H,57,69)(H,58,70)(H,59,71)(H,60,72)(H,61,67)(H,62,68)(H,63,73)(H,64,74)/t31-,32-,43+,44+,45+,46+/m1/s1 XBOROKFRDNQVOY-ATTIMZMDSA-N 50069563 Biphalin Analogue::CHEMBL2371079 Mu-type opioid receptor Cavia cutleri 2.2 ChEMBL 10.1016/s0960-894x(98)00065-1 10.7270/Q2736Q17 9871617 Li, G; Haq, W; Xiang, L; Lou, BS; Hughes, R; De Leon, IA; Davis, P; Gillespie, TJ; Romanowski, M; Zhu, X; Misicka, A; Lipkowski, AW; Porreca, F; Davis, TP; Yamamura, HI; O'Brien, DF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069563&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73345526 103963623 CHEMBL2371079 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50007848 CC1Oc2c(cccc2O)C11CCN(C)CC1 InChI=1S/C14H19NO2/c1-10-14(6-8-15(2)9-7-14)11-4-3-5-12(16)13(11)17-10/h3-5,10,16H,6-9H2,1-2H3 BOUCSCXAHDVKAT-UHFFFAOYSA-N 50070948 1',2-dimethylspiro[2,3-dihydrobenzo[b]furan-3,4'-(hexahydropyridine)]-7-ol::CHEMBL50098 Mu-type opioid receptor Cavia cutleri 124 ChEMBL 10.1016/s0960-894x(98)00318-7 10.7270/Q2K073D5 9873439 Tsai, YC; Liou, JP; Liao, R; Cheng, CY; Tao, PL National Taiwan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070948&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44296582 103964756 CHEMBL50098 ZINC29481606 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50007852 CCC1Oc2c(cccc2O)C11CCN(C)CC1 InChI=1S/C15H21NO2/c1-3-13-15(7-9-16(2)10-8-15)11-5-4-6-12(17)14(11)18-13/h4-6,13,17H,3,7-10H2,1-2H3 LQACPCZDXSYESU-UHFFFAOYSA-N 50070947 2-ethyl-1'-methylspiro[2,3-dihydrobenzo[b]furan-3,4'-(hexahydropyridine)]-7-ol::CHEMBL431156 Mu-type opioid receptor Cavia cutleri 102 ChEMBL 10.1016/s0960-894x(98)00318-7 10.7270/Q2K073D5 9873439 Tsai, YC; Liou, JP; Liao, R; Cheng, CY; Tao, PL National Taiwan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070947&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44296549 103964755 CHEMBL431156 ZINC29479095 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50007856 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 38 ChEMBL 10.1016/s0960-894x(98)00318-7 10.7270/Q2K073D5 9873439 Tsai, YC; Liou, JP; Liao, R; Cheng, CY; Tao, PL National Taiwan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50007857 CC1CN(C)CCC11COc2c1cccc2O InChI=1S/C14H19NO2/c1-10-8-15(2)7-6-14(10)9-17-13-11(14)4-3-5-12(13)16/h3-5,10,16H,6-9H2,1-2H3 BQENLWFUKSDROS-UHFFFAOYSA-N 50070946 1',3'-dimethylspiro[2,3-dihydrobenzo[b]furan-3,4'-(hexahydropyridine)]-7-ol::CHEMBL300689 Mu-type opioid receptor Cavia cutleri 1015 ChEMBL 10.1016/s0960-894x(98)00318-7 10.7270/Q2K073D5 9873439 Tsai, YC; Liou, JP; Liao, R; Cheng, CY; Tao, PL National Taiwan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070946&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44296512 103964754 CHEMBL300689 ZINC29481392 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50007858 CN1CCC2(COc3c2cccc3O)CC1 InChI=1S/C13H17NO2/c1-14-7-5-13(6-8-14)9-16-12-10(13)3-2-4-11(12)15/h2-4,15H,5-9H2,1H3 YNRDWVIYBCVSGZ-UHFFFAOYSA-N 50070949 1'-methylspiro[2,3-dihydrobenzo[b]furan-3,4'-(hexahydropyridine)]-7-ol::CHEMBL297281 Mu-type opioid receptor Cavia cutleri 1654 ChEMBL 10.1016/s0960-894x(98)00318-7 10.7270/Q2K073D5 9873439 Tsai, YC; Liou, JP; Liao, R; Cheng, CY; Tao, PL National Taiwan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070949 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070949&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10680393 103964757 CHEMBL297281 ZINC29481386 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50007863 CCOC(=O)C1(CCN(C)CC1)c1ccccc1 InChI=1S/C15H21NO2/c1-3-18-14(17)15(9-11-16(2)12-10-15)13-7-5-4-6-8-13/h4-8H,3,9-12H2,1-2H3 XADCESSVHJOZHK-UHFFFAOYSA-N 50026752 1-Methyl-4-phenyl-piperidine-4-carboxylic acid ethyl ester::1-Methyl-4-phenyl-piperidine-4-carboxylic acid ethyl ester(Meperidine)::4-Ethoxycarbonyl-1-methyl-4-phenyl-piperidinium::CHEMBL607::Demerol::MEPERIDINE::MEPERIDINE HYDROCHLORIDE::Mepergan::Pethidine::ethyl 1-methyl-4-phenylpiperidine-4-carboxylate Mu-type opioid receptor Cavia cutleri 451 ChEMBL 10.1016/s0960-894x(98)00318-7 10.7270/Q2K073D5 9873439 Tsai, YC; Liou, JP; Liao, R; Cheng, CY; Tao, PL National Taiwan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026752 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026752&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 4058 103936336 CHEMBL607 DB00454 7221 C07128 ZINC00001681 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057610 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)C1(CCc2ccccc2C1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C39H54N8O10/c1-20(2)31(36(55)42-19-29(41)49)46-37(56)32(21(3)4)45-35(54)28(17-30(50)51)44-38(57)39(15-14-24-8-6-7-9-25(24)18-39)47-33(52)22(5)43-34(53)27(40)16-23-10-12-26(48)13-11-23/h6-13,20-22,27-28,31-32,48H,14-19,40H2,1-5H3,(H2,41,49)(H,42,55)(H,43,53)(H,44,57)(H,45,54)(H,46,56)(H,47,52)(H,50,51)/t22-,27+,28+,31+,32+,39?/m1/s1 WCJNWJPRBIKFOI-RKPARCAKSA-N 50001459 3-[(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-1,2,3,4-tetrahydro-naphthalene-2-carbonyl)-amino]-N-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL124941::H-Tyr-D-Ala-(R or S)Atc-Asp-Val-Val-Gly-NH2 Mu-type opioid receptor Cavia cutleri 1380 ChEMBL 10.1021/jm00099a025 10.7270/Q2H70DRH 1331451 Schiller, PW; Weltrowska, G; Nguyen, TM; Wilkes, BC; Chung, NN; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001459&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44348645 103915924 CHEMBL124941 ZINC95548274 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50005621 Oc1ccc2C[C@H]3N(CC4CC4)CCC45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)NC(=O)\C=C\c1ccc(Cl)cc1 InChI=1S/C29H31ClN2O4/c30-20-7-3-17(4-8-20)5-10-24(34)31-21-11-12-29(35)23-15-19-6-9-22(33)26-25(19)28(29,27(21)36-26)13-14-32(23)16-18-1-2-18/h3-10,18,21,23,27,33,35H,1-2,11-16H2,(H,31,34)/b10-5+/t21-,23-,27+,28?,29-/m1/s1 RPKXTHDVAPAPMQ-VPJFHMJASA-N 50287928 1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-yl]-3-(4-chlorophenyl)-(E)-2-propenamide::CHEMBL296693 Mu-type opioid receptor Cavia cutleri 0.100000 ChEMBL 10.1016/0960-894X(95)00583-F 10.7270/Q2QJ7H83 Derrick, I; Moynihan, HA; Broadbear, J; Woods, JH; Lewis, JW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287928 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287928&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44292987 104129499 CHEMBL296693 ZINC29411261 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50005624 Oc1ccc2C[C@H]3N(CC4CC4)CCC45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)NC(=O)\C=C\c1ccc(cc1)[N+]([O-])=O InChI=1S/C29H31N3O6/c33-22-9-6-19-15-23-29(35)12-11-21(30-24(34)10-5-17-3-7-20(8-4-17)32(36)37)27-28(29,25(19)26(22)38-27)13-14-31(23)16-18-1-2-18/h3-10,18,21,23,27,33,35H,1-2,11-16H2,(H,30,34)/b10-5+/t21-,23-,27+,28?,29-/m1/s1 XSKHBVUTYWENGE-VPJFHMJASA-N 50287927 1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-yl]-3-(4-nitrophenyl)-(E)-2-propenamide::CHEMBL417535 Mu-type opioid receptor Cavia cutleri 0.200000 ChEMBL 10.1016/0960-894X(95)00583-F 10.7270/Q2QJ7H83 Derrick, I; Moynihan, HA; Broadbear, J; Woods, JH; Lewis, JW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287927 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287927&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10256020 104129498 CHEMBL417535 ZINC29413339 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50005640 Cc1ccc(\C=C\C(=O)N[C@@H]2CC[C@@]3(O)[C@H]4Cc5ccc(O)c6O[C@@H]2C3(CCN4CC2CC2)c56)cc1 InChI=1S/C30H34N2O4/c1-18-2-4-19(5-3-18)8-11-25(34)31-22-12-13-30(35)24-16-21-9-10-23(33)27-26(21)29(30,28(22)36-27)14-15-32(24)17-20-6-7-20/h2-5,8-11,20,22,24,28,33,35H,6-7,12-17H2,1H3,(H,31,34)/b11-8+/t22-,24-,28+,29?,30-/m1/s1 JZKZQHCZPOYVJT-GPBMLUTFSA-N 50287929 1N-[4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,14R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-yl]-3-(4-methylphenyl)-(E)-2-propenamide::CHEMBL297756 Mu-type opioid receptor Cavia cutleri 0.230000 ChEMBL 10.1016/0960-894X(95)00583-F 10.7270/Q2QJ7H83 Derrick, I; Moynihan, HA; Broadbear, J; Woods, JH; Lewis, JW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287929 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287929&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44292946 104129500 CHEMBL297756 ZINC29414863 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50005644 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)NC(=O)\C=C\c1ccccc1 InChI=1S/C29H32N2O4/c32-22-10-9-20-16-23-29(34)13-12-21(30-24(33)11-8-18-4-2-1-3-5-18)27-28(29,25(20)26(22)35-27)14-15-31(23)17-19-6-7-19/h1-5,8-11,19,21,23,27,32,34H,6-7,12-17H2,(H,30,33)/b11-8+/t21-,23-,27+,28+,29-/m1/s1 LZOHGRMVIRLGGP-ZHWHHXEDSA-N 50248793 17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5alpha-epoxy-6beta-(cinnamoylamino)morphinan::CHEMBL473362 Mu-type opioid receptor Cavia cutleri 0.070000 ChEMBL 10.1016/0960-894X(95)00583-F 10.7270/Q2QJ7H83 Derrick, I; Moynihan, HA; Broadbear, J; Woods, JH; Lewis, JW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50248793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50248793&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 24822299 104103334 CHEMBL473362 ZINC29405055 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50005646 COC(=O)\C=C\C(=O)N[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45 InChI=1S/C25H30N2O6/c1-32-20(30)7-6-19(29)26-16-8-9-25(31)18-12-15-4-5-17(28)22-21(15)24(25,23(16)33-22)10-11-27(18)13-14-2-3-14/h4-7,14,16,18,23,28,31H,2-3,8-13H2,1H3,(H,26,29)/b7-6+/t16-,18-,23+,24+,25-/m1/s1 PQKHESYTSKMWFP-WZJCLRDWSA-N 50247803 Beta-Funeltrexamine::CHEMBL473136::beta-funaltrexamine::methyl (2E)-3-{[(1S,5R,13R,14R,17S)-4-(cyclopropylmethyl)-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10-trien-14-yl]carbamoyl}prop-2-enoate::methyl 3-[4-cyclopropylmethyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-ylcarbamoyl]-(E)-2-propenoate Mu-type opioid receptor Cavia cutleri 0.400000 ChEMBL 10.1016/0960-894X(95)00583-F 10.7270/Q2QJ7H83 Derrick, I; Moynihan, HA; Broadbear, J; Woods, JH; Lewis, JW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50247803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50247803&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311018 104102600 CHEMBL473136 1631 C18127 ZINC03995756 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50006894 CN([C@@H](CN1CCCC1)c1cccc(N)c1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C21H25Cl2N3O/c1-25(21(27)12-15-7-8-18(22)19(23)11-15)20(14-26-9-2-3-10-26)16-5-4-6-17(24)13-16/h4-8,11,13,20H,2-3,9-10,12,14,24H2,1H3/t20-/m0/s1 GZGGYQMNFMHDFI-FQEVSTJZSA-N 50290074 CHEMBL558597::N-[(R)-1-(3-Amino-phenyl)-2-pyrrolidin-1-yl-ethyl]-2-(3,4-dichloro-phenyl)-N-methyl-acetamide; hydrochloride Mu-type opioid receptor Cavia cutleri 1380 ChEMBL 10.1016/S0960-894X(97)00406-X 10.7270/Q2GB242Q Pechulis, AD; Archer, S; Wentland, MP; Colasurdo, AM; Bidlack, JM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290074&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15130837 104131645 CHEMBL558597 ZINC11689574 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50006896 CN([C@H](CN1CCCC1)c1cccc(N)c1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C21H25Cl2N3O/c1-25(21(27)12-15-7-8-18(22)19(23)11-15)20(14-26-9-2-3-10-26)16-5-4-6-17(24)13-16/h4-8,11,13,20H,2-3,9-10,12,14,24H2,1H3/t20-/m1/s1 GZGGYQMNFMHDFI-HXUWFJFHSA-N 50290071 CHEMBL542149::N-[(S)-1-(3-Amino-phenyl)-2-pyrrolidin-1-yl-ethyl]-2-(3,4-dichloro-phenyl)-N-methyl-acetamide; hydrochloride Mu-type opioid receptor Cavia cutleri 7.7 ChEMBL 10.1016/S0960-894X(97)00406-X 10.7270/Q2GB242Q Pechulis, AD; Archer, S; Wentland, MP; Colasurdo, AM; Bidlack, JM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290071&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10456060 104131642 CHEMBL542149 ZINC00599445 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50006898 CN([C@@H](CN1CCCC1)c1cccc(NC(=S)Nc2ccc(c(c2)C(O)=O)-c2c3ccc(O)cc3oc3cc(=O)ccc23)c1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C42H36Cl2N4O6S/c1-47(39(51)18-24-7-14-34(43)35(44)17-24)36(23-48-15-2-3-16-48)25-5-4-6-26(19-25)45-42(55)46-27-8-11-30(33(20-27)41(52)53)40-31-12-9-28(49)21-37(31)54-38-22-29(50)10-13-32(38)40/h4-14,17,19-22,36,49H,2-3,15-16,18,23H2,1H3,(H,52,53)(H2,45,46,55)/t36-/m0/s1 BNQHZDZAQDLXCJ-BHVANESWSA-N 50290073 5-{3-[3-((R)-1-{[2-(3,4-Dichloro-phenyl)-acetyl]-methyl-amino}-2-pyrrolidin-1-yl-ethyl)-phenyl]-thioureido}-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-benzoic acid::CHEMBL310636 Mu-type opioid receptor Cavia cutleri 1190 ChEMBL 10.1016/S0960-894X(97)00406-X 10.7270/Q2GB242Q Pechulis, AD; Archer, S; Wentland, MP; Colasurdo, AM; Bidlack, JM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290073&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44312914 104131644 CHEMBL310636 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50006899 CN([C@H](CN1CCCC1)c1cccc(NC(=S)Nc2ccc(c(c2)C(O)=O)-c2c3ccc(O)cc3oc3cc(=O)ccc23)c1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C42H36Cl2N4O6S/c1-47(39(51)18-24-7-14-34(43)35(44)17-24)36(23-48-15-2-3-16-48)25-5-4-6-26(19-25)45-42(55)46-27-8-11-30(33(20-27)41(52)53)40-31-12-9-28(49)21-37(31)54-38-22-29(50)10-13-32(38)40/h4-14,17,19-22,36,49H,2-3,15-16,18,23H2,1H3,(H,52,53)(H2,45,46,55)/t36-/m1/s1 BNQHZDZAQDLXCJ-PSXMRANNSA-N 50290072 5-{3-[3-((S)-1-{[2-(3,4-Dichloro-phenyl)-acetyl]-methyl-amino}-2-pyrrolidin-1-yl-ethyl)-phenyl]-thioureido}-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-benzoic acid::CHEMBL308813 Mu-type opioid receptor Cavia cutleri 98 ChEMBL 10.1016/S0960-894X(97)00406-X 10.7270/Q2GB242Q Pechulis, AD; Archer, S; Wentland, MP; Colasurdo, AM; Bidlack, JM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290072&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10676779 104131643 CHEMBL308813 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50006920 CN(C(CN1CCCC1)c1cccc(NC(=S)Nc2ccc(c(c2)C(O)=O)-c2c3ccc(O)cc3oc3cc(=O)ccc23)c1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C42H36Cl2N4O6S/c1-47(39(51)18-24-7-14-34(43)35(44)17-24)36(23-48-15-2-3-16-48)25-5-4-6-26(19-25)45-42(55)46-27-8-11-30(33(20-27)41(52)53)40-31-12-9-28(49)21-37(31)54-38-22-29(50)10-13-32(38)40/h4-14,17,19-22,36,49H,2-3,15-16,18,23H2,1H3,(H,52,53)(H2,45,46,55) BNQHZDZAQDLXCJ-UHFFFAOYSA-N 50290070 5-{3-[3-(1-{[2-(3,4-Dichloro-phenyl)-acetyl]-methyl-amino}-2-pyrrolidin-1-yl-ethyl)-phenyl]-thioureido}-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-benzoic acid::CHEMBL307919 Mu-type opioid receptor Cavia cutleri 176 ChEMBL 10.1016/S0960-894X(97)00406-X 10.7270/Q2GB242Q Pechulis, AD; Archer, S; Wentland, MP; Colasurdo, AM; Bidlack, JM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290070 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290070&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10533341 104131641 CHEMBL307919 ZINC95540575 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50006922 CN([C@@H](CN1CCCC1)c1cccc(NC(C)=O)c1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C23H27Cl2N3O2/c1-16(29)26-19-7-5-6-18(14-19)22(15-28-10-3-4-11-28)27(2)23(30)13-17-8-9-20(24)21(25)12-17/h5-9,12,14,22H,3-4,10-11,13,15H2,1-2H3,(H,26,29)/t22-/m0/s1 FCEBQYDCYXPCAL-QFIPXVFZSA-N 50290075 CHEMBL542403::N-[(R)-1-(3-Acetylamino-phenyl)-2-pyrrolidin-1-yl-ethyl]-2-(3,4-dichloro-phenyl)-N-methyl-acetamide; hydrochloride Mu-type opioid receptor Cavia cutleri 1040 ChEMBL 10.1016/S0960-894X(97)00406-X 10.7270/Q2GB242Q Pechulis, AD; Archer, S; Wentland, MP; Colasurdo, AM; Bidlack, JM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290075 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290075&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15130838 104131646 CHEMBL542403 ZINC13446391 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50006924 CN([C@H](CN1CCCC1)c1cccc(NC(C)=O)c1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C23H27Cl2N3O2/c1-16(29)26-19-7-5-6-18(14-19)22(15-28-10-3-4-11-28)27(2)23(30)13-17-8-9-20(24)21(25)12-17/h5-9,12,14,22H,3-4,10-11,13,15H2,1-2H3,(H,26,29)/t22-/m1/s1 FCEBQYDCYXPCAL-JOCHJYFZSA-N 50290076 CHEMBL558596::N-[(S)-1-(3-Acetylamino-phenyl)-2-pyrrolidin-1-yl-ethyl]-2-(3,4-dichloro-phenyl)-N-methyl-acetamide; hydrochloride Mu-type opioid receptor Cavia cutleri 8.4 ChEMBL 10.1016/S0960-894X(97)00406-X 10.7270/Q2GB242Q Pechulis, AD; Archer, S; Wentland, MP; Colasurdo, AM; Bidlack, JM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290076&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10028324 104131647 CHEMBL558596 ZINC00599446 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50008167 CC1(C)SSC[C@@H](NC(=O)[C@@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(O)=O InChI=1S/C26H32N4O5S2/c1-26(2)21(25(34)35)30-23(32)19(14-17-11-7-4-8-12-17)28-24(33)20(15-36-37-26)29-22(31)18(27)13-16-9-5-3-6-10-16/h3-12,18-21H,13-15,27H2,1-2H3,(H,28,33)(H,29,31)(H,30,32)(H,34,35)/t18-,19-,20+,21+/m0/s1 MVYCTWGUOLFOFH-UWHLTILDSA-N 50071862 10-(2-Amino-3-phenyl-propionylamino)-7-benzyl-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL2370162 Mu-type opioid receptor Cavia cutleri 610 ChEMBL 10.1016/s0960-894x(98)00476-4 10.7270/Q24T6JWP 9873602 Mosberg, HI; Ho, JC; Sobczyk-Kojiro, K University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071862&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73350058 103965572 CHEMBL2370162 ZINC36221810 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50008168 CC1(C)SCCSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(N)=O InChI=1S/C28H37N5O5S2/c1-28(2)23(24(30)35)33-26(37)21(15-17-6-4-3-5-7-17)31-27(38)22(16-39-12-13-40-28)32-25(36)20(29)14-18-8-10-19(34)11-9-18/h3-11,20-23,34H,12-16,29H2,1-2H3,(H2,30,35)(H,31,38)(H,32,36)(H,33,37)/t20-,21-,22+,23+/m0/s1 LPNIKGPUPANXLO-MYDTUXCISA-N 50071861 12-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-9-benzyl-5,5-dimethyl-8,11-dioxo-1,4-dithia-7,10-diaza-cyclotridecane-6-carboxylic acid amide::CHEMBL2370165 Mu-type opioid receptor Cavia cutleri 0.290000 ChEMBL 10.1016/s0960-894x(98)00476-4 10.7270/Q24T6JWP 9873602 Mosberg, HI; Ho, JC; Sobczyk-Kojiro, K University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071861&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73348469 103965571 CHEMBL2370165 ZINC36221804 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50008172 CC1(C)SSC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(O)=O InChI=1S/C26H32N4O6S2/c1-26(2)21(25(35)36)30-23(33)19(13-15-6-4-3-5-7-15)28-24(34)20(14-37-38-26)29-22(32)18(27)12-16-8-10-17(31)11-9-16/h3-11,18-21,31H,12-14,27H2,1-2H3,(H,28,34)(H,29,32)(H,30,33)(H,35,36)/t18-,19-,20-,21+/m0/s1 BLNPATOSLCUUSL-XSDIEEQYSA-N 50000655 (4R,7S,10R)-10-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL39192 Mu-type opioid receptor Cavia cutleri 52 ChEMBL 10.1016/s0960-894x(98)00476-4 10.7270/Q24T6JWP 9873602 Mosberg, HI; Ho, JC; Sobczyk-Kojiro, K University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000655 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000655&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44285718 103915203 CHEMBL39192 ZINC26648527 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50008175 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C)[C@@H](Cc1ccccc1)C(=O)NCCO InChI=1S/C26H35N5O6/c1-17(30-25(36)21(27)14-19-8-10-20(33)11-9-19)24(35)29-16-23(34)31(2)22(26(37)28-12-13-32)15-18-6-4-3-5-7-18/h3-11,17,21-22,32-33H,12-16,27H2,1-2H3,(H,28,37)(H,29,35)(H,30,36)/t17-,21+,22+/m1/s1 HPZJMUBDEAMBFI-WTNAPCKOSA-N 21015 (2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]-N-methylacetamido}-N-(2-hydroxyethyl)-3-phenylpropanamide::2-Ala-4-MePhe-5-Gly-Enkephalin::CHEMBL38874::D-Ala2-MePhe4-Met(0)5-enkephalin-ol::DAMGO::RX 783006::US11492374, ID 2::[3H]DAMGO::[tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephalin Mu-type opioid receptor Cavia cutleri 0.990000 ChEMBL 10.1016/s0960-894x(98)00476-4 10.7270/Q24T6JWP 9873602 Mosberg, HI; Ho, JC; Sobczyk-Kojiro, K University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21015&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5462471 49689088 CHEMBL38874 1647 C04080 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50008176 CC1(C)SCCSC[C@@H](NC(=O)[C@@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(N)=O InChI=1S/C28H37N5O4S2/c1-28(2)23(24(30)34)33-26(36)21(16-19-11-7-4-8-12-19)31-27(37)22(17-38-13-14-39-28)32-25(35)20(29)15-18-9-5-3-6-10-18/h3-12,20-23H,13-17,29H2,1-2H3,(H2,30,34)(H,31,37)(H,32,35)(H,33,36)/t20-,21-,22+,23+/m0/s1 TUBSLXKBCFFBPE-MYDTUXCISA-N 50071860 12-(2-Amino-3-phenyl-propionylamino)-9-benzyl-5,5-dimethyl-8,11-dioxo-1,4-dithia-7,10-diaza-cyclotridecane-6-carboxylic acid amide::CHEMBL2370161 Mu-type opioid receptor Cavia cutleri 1.4 ChEMBL 10.1016/s0960-894x(98)00476-4 10.7270/Q24T6JWP 9873602 Mosberg, HI; Ho, JC; Sobczyk-Kojiro, K University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071860&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73345445 103965570 CHEMBL2370161 ZINC36221165 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50008180 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 6.5 ChEMBL 10.1016/s0960-894x(98)00472-7 10.7270/Q2154HJJ 9873603 Wang, C; McFadyen, IJ; Traynor, JR; Mosberg, HI University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50008182 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NC1CCNc2ccc(Cc3ccccc3)cc12 InChI=1S/C27H31N3O2/c1-17-12-21(31)13-18(2)22(17)16-24(28)27(32)30-26-10-11-29-25-9-8-20(15-23(25)26)14-19-6-4-3-5-7-19/h3-9,12-13,15,24,26,29,31H,10-11,14,16,28H2,1-2H3,(H,30,32)/t24-,26?/m0/s1 VTFUYBNMSGPAQU-QSAPEBAKSA-N 50071865 (S)-2-Amino-N-(6-benzyl-1,2,3,4-tetrahydro-quinolin-4-yl)-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionamide::CHEMBL432045 Mu-type opioid receptor Cavia cutleri 2.6 ChEMBL 10.1016/s0960-894x(98)00472-7 10.7270/Q2154HJJ 9873603 Wang, C; McFadyen, IJ; Traynor, JR; Mosberg, HI University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071865&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323614 103965575 CHEMBL432045 ZINC26646700 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50008221 CCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 InChI=1S/C22H28N2O/c1-2-22(25)24(20-11-7-4-8-12-20)21-14-17-23(18-15-21)16-13-19-9-5-3-6-10-19/h3-12,21H,2,13-18H2,1H3 PJMPHNIQZUBGLI-UHFFFAOYSA-N 50008984 4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-phthalazin-1-one::CHEMBL596::Duragesic-100::Duragesic-12::Duragesic-25::Duragesic-50::Duragesic-75::FENTANYL::FENTANYL CITRATE::FENTANYL-HCl::Fentanyl-100::Fentanyl-12::Fentanyl-25::Fentanyl-50::Fentanyl-75::Fentora::Innovar::Ionsys::N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide::N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide(Fentanyl)::N-(1-phenethylpiperidin-4-yl)-N-phenylpropionamide Mu-type opioid receptor Cavia cutleri 8.5 ChEMBL 10.1016/s0960-894x(98)00472-7 10.7270/Q2154HJJ 9873603 Wang, C; McFadyen, IJ; Traynor, JR; Mosberg, HI University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008984&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 7V7 5TZO,8EF5,7U64 3345 103922051 119915 CHEMBL596 DB00813 1626 ZINC02522669 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50008222 CC1(C)SSC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(O)=O InChI=1S/C26H32N4O6S2/c1-26(2)21(25(35)36)30-23(33)19(13-15-6-4-3-5-7-15)28-24(34)20(14-37-38-26)29-22(32)18(27)12-16-8-10-17(31)11-9-16/h3-11,18-21,31H,12-14,27H2,1-2H3,(H,28,34)(H,29,32)(H,30,33)(H,35,36)/t18-,19-,20-,21+/m0/s1 BLNPATOSLCUUSL-XSDIEEQYSA-N 50000655 (4R,7S,10R)-10-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL39192 Mu-type opioid receptor Cavia cutleri 52 ChEMBL 10.1016/s0960-894x(98)00472-7 10.7270/Q2154HJJ 9873603 Wang, C; McFadyen, IJ; Traynor, JR; Mosberg, HI University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000655 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000655&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44285718 103915203 CHEMBL39192 ZINC26648527 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50008226 CC1(C)SSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(N)=O InChI=1S/C26H33N5O5S2/c1-26(2)21(22(28)33)31-24(35)19(13-15-6-4-3-5-7-15)29-25(36)20(14-37-38-26)30-23(34)18(27)12-16-8-10-17(32)11-9-16/h3-11,18-21,32H,12-14,27H2,1-2H3,(H2,28,33)(H,29,36)(H,30,34)(H,31,35)/t18-,19-,20+,21+/m0/s1 VDYOLQMTBBHOCK-UWHLTILDSA-N 50071864 10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid amide::CHEMBL2370163 Mu-type opioid receptor Cavia cutleri 7 ChEMBL 10.1016/s0960-894x(98)00472-7 10.7270/Q2154HJJ 9873603 Wang, C; McFadyen, IJ; Traynor, JR; Mosberg, HI University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071864&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73348468 103965574 CHEMBL2370163 ZINC36221817 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50012724 CNc1ccc2CC3[C@H](C)[C@](C)(CCN3CC3CC3)c2c1 InChI=1S/C19H28N2/c1-13-18-10-15-6-7-16(20-3)11-17(15)19(13,2)8-9-21(18)12-14-4-5-14/h6-7,11,13-14,18,20H,4-5,8-10,12H2,1-3H3/t13-,18?,19-/m0/s1 ZYIYQDGBJHOITC-IMWIMMFESA-N 50085029 ((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-methyl-amine::(3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-methyl-amine::(3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-methyl-amine.2HCl.C2H6O.H2O::CHEMBL291751 Mu-type opioid receptor Cavia cutleri 13 ChEMBL 10.1016/s0960-894x(99)00670-8 10.7270/Q2571CH7 10673107 Wentland, MP; Xu, G; Cioffi, CL; Ye, Y; Duan, W; Cohen, DJ; Colasurdo, AM; Bidlack, JM Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085029&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44298233 103984512 CHEMBL291751 ZINC29553596 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50012727 C[C@H]1[C@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C18H25NO/c1-12-17-9-14-5-6-15(20)10-16(14)18(12,2)7-8-19(17)11-13-3-4-13/h5-6,10,12-13,17,20H,3-4,7-9,11H2,1-2H3/t12-,17?,18-/m0/s1 YQYVFVRQLZMJKJ-PEYLTSRESA-N 50083926 (6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::(SSR)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyclo[9.1.1.0*3,8*]trideca-3(8),4,6-trien-6-ol(cyclazocine)::(cyclazocine)2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid::10-cyclopropylmethyl-1,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol(Cyclazocine)::3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol (cyclazocine)::3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Cyclazocine)::3-Cyclopropylmethyl-8-hydroxy-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocinium::3-Cyclopropylmethyl-8-hydroxy-6,11-dimethyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one ((-)cyclazocine)::BDBM50451129::CHEMBL3085528::CYCLAZOCINE Mu-type opioid receptor Cavia cutleri 0.320000 ChEMBL 10.1016/s0960-894x(99)00670-8 10.7270/Q2571CH7 10673107 Wentland, MP; Xu, G; Cioffi, CL; Ye, Y; Duan, W; Cohen, DJ; Colasurdo, AM; Bidlack, JM Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083926 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083926&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10016044 103983527 CHEMBL3085528 ZINC01699599 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50012728 C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)N(C)C InChI=1S/C20H30N2/c1-14-19-11-16-7-8-17(21(3)4)12-18(16)20(14,2)9-10-22(19)13-15-5-6-15/h7-8,12,14-15,19H,5-6,9-11,13H2,1-4H3/t14-,19?,20-/m0/s1 YXOMKMVDHCVFCR-JUJMCKSGSA-N 50085022 ((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-dimethyl-amine::(3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-dimethyl-amine::(3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-dimethyl-amine.2HCl::CHEMBL299114 Mu-type opioid receptor Cavia cutleri 82 ChEMBL 10.1016/s0960-894x(99)00670-8 10.7270/Q2571CH7 10673107 Wentland, MP; Xu, G; Cioffi, CL; Ye, Y; Duan, W; Cohen, DJ; Colasurdo, AM; Bidlack, JM Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085022 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085022&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44298207 103984505 CHEMBL299114 ZINC13493437 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50012729 C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)N1CCCC1 InChI=1S/C22H32N2/c1-16-21-13-18-7-8-19(23-10-3-4-11-23)14-20(18)22(16,2)9-12-24(21)15-17-5-6-17/h7-8,14,16-17,21H,3-6,9-13,15H2,1-2H3/t16-,21?,22-/m0/s1 RHNGZRXXVLXNOE-URJRECBDSA-N 50085025 (6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-8-pyrrolidin-1-yl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::3-Cyclopropylmethyl-6,11-dimethyl-8-pyrrolidin-1-yl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::CHEMBL55948 Mu-type opioid receptor Cavia cutleri 770 ChEMBL 10.1016/s0960-894x(99)00670-8 10.7270/Q2571CH7 10673107 Wentland, MP; Xu, G; Cioffi, CL; Ye, Y; Duan, W; Cohen, DJ; Colasurdo, AM; Bidlack, JM Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085025&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44298206 103984508 CHEMBL55948 ZINC29547240 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50012731 C[C@H]1C2Cc3ccc(N)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C18H26N2/c1-12-17-9-14-5-6-15(19)10-16(14)18(12,2)7-8-20(17)11-13-3-4-13/h5-6,10,12-13,17H,3-4,7-9,11,19H2,1-2H3/t12-,17?,18-/m0/s1 STNPURITMRUHGJ-PEYLTSRESA-N 50085024 (6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ylamine::3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ylamine::3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ylamine.2HCl::CHEMBL52399 Mu-type opioid receptor Cavia cutleri 780 ChEMBL 10.1016/s0960-894x(99)00670-8 10.7270/Q2571CH7 10673107 Wentland, MP; Xu, G; Cioffi, CL; Ye, Y; Duan, W; Cohen, DJ; Colasurdo, AM; Bidlack, JM Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085024&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44298187 103984507 CHEMBL52399 ZINC13493410 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50012822 C[C@H]1C2Cc3ccc(NCCc4ccccc4)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C26H34N2/c1-19-25-16-22-10-11-23(27-14-12-20-6-4-3-5-7-20)17-24(22)26(19,2)13-15-28(25)18-21-8-9-21/h3-7,10-11,17,19,21,25,27H,8-9,12-16,18H2,1-2H3/t19-,25?,26-/m0/s1 CBEQNEFYEBRKMD-JKEZHHNBSA-N 50085023 ((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-phenethyl-amine::(3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-phenethyl-amine::CHEMBL56165 Mu-type opioid receptor Cavia cutleri 9 ChEMBL 10.1016/s0960-894x(99)00670-8 10.7270/Q2571CH7 10673107 Wentland, MP; Xu, G; Cioffi, CL; Ye, Y; Duan, W; Cohen, DJ; Colasurdo, AM; Bidlack, JM Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085023&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44298221 103984506 CHEMBL56165 ZINC29553517 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50012824 C[C@H]1[C@H]2Cc3ccc(Nc4ccccc4)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C24H30N2/c1-17-23-14-19-10-11-21(25-20-6-4-3-5-7-20)15-22(19)24(17,2)12-13-26(23)16-18-8-9-18/h3-7,10-11,15,17-18,23,25H,8-9,12-14,16H2,1-2H3/t17-,23+,24-/m0/s1 FUMBLBJFVJXVBV-VWMXVWASSA-N 50369586 CHEMBL326516 Mu-type opioid receptor Cavia cutleri 1.30 ChEMBL 10.1016/s0960-894x(99)00670-8 10.7270/Q2571CH7 10673107 Wentland, MP; Xu, G; Cioffi, CL; Ye, Y; Duan, W; Cohen, DJ; Colasurdo, AM; Bidlack, JM Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369586 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369586&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73351393 160848688 CHEMBL326516 ZINC13493417 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010706 FC(F)(F)c1ccc(CC(=O)N2CCCC[C@H]2CN2CCCC2)cc1 InChI=1S/C19H25F3N2O/c20-19(21,22)16-8-6-15(7-9-16)13-18(25)24-12-2-1-5-17(24)14-23-10-3-4-11-23/h6-9,17H,1-5,10-14H2/t17-/m0/s1 RFTWMVGLYKJUCZ-KRWDZBQOSA-N 50007164 (S)-1-(2-Pyrrolidin-1-ylmethyl-piperidin-1-yl)-2-(4-trifluoromethyl-phenyl)-ethanone(BRL 52656)::1-((S)-2-Pyrrolidin-1-ylmethyl-piperidin-1-yl)-2-(4-trifluoromethyl-phenyl)-ethanone::1-(2-Pyrrolidin-1-ylmethyl-piperidin-1-yl)-2-(4-trifluoromethyl-phenyl)-ethanone::BRL-52656::CHEMBL433508 Mu-type opioid receptor Cavia cutleri 2341 ChEMBL 10.1021/jm00112a042 10.7270/Q2CV4GPX 1652025 Vecchietti, V; Clarke, GD; Colle, R; Giardina, G; Petrone, G; Sbacchi, M Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007164 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007164&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9865223 103920447 CHEMBL433508 ZINC00575546 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010708 Clc1ccc(CC(=O)N2CCc3[nH]c4ccccc4c3C2CN2CCCC2)cc1Cl InChI=1S/C24H25Cl2N3O/c25-18-8-7-16(13-19(18)26)14-23(30)29-12-9-21-24(17-5-1-2-6-20(17)27-21)22(29)15-28-10-3-4-11-28/h1-2,5-8,13,22,27H,3-4,9-12,14-15H2 SRBDHMOWSKFOIL-UHFFFAOYSA-N 50007163 2-(3,4-Dichloro-phenyl)-1-(1-pyrrolidin-1-ylmethyl-1,3,4,5-tetrahydro-pyrido[4,3-b]indol-2-yl)-ethanone;0.5H2O::CHEMBL330449 Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm00112a042 10.7270/Q2CV4GPX 1652025 Vecchietti, V; Clarke, GD; Colle, R; Giardina, G; Petrone, G; Sbacchi, M Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007163 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007163&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15697379 103920446 CHEMBL330449 ZINC13823977 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010709 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 3.3 ChEMBL 10.1021/jm00112a042 10.7270/Q2CV4GPX 1652025 Vecchietti, V; Clarke, GD; Colle, R; Giardina, G; Petrone, G; Sbacchi, M Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010710 CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C19H26Cl2N2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17-,18-/m1/s1 VQLPLYSROCPWFF-QZTJIDSGSA-N 50000296 CHEMBL441765::CHEMBL482811::U-50488H::US11492374, ID 1 Mu-type opioid receptor Cavia cutleri 616 ChEMBL 10.1021/jm00112a042 10.7270/Q2CV4GPX 1652025 Vecchietti, V; Clarke, GD; Colle, R; Giardina, G; Petrone, G; Sbacchi, M Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000296&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036289 103914903 73358 CHEMBL482811CHEMBL441765 1654 C11796 ZINC00643032 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010712 Clc1ccc(CC(=O)N2CCc3ccccc3C2CN2CCCC2)cc1Cl InChI=1S/C22H24Cl2N2O/c23-19-8-7-16(13-20(19)24)14-22(27)26-12-9-17-5-1-2-6-18(17)21(26)15-25-10-3-4-11-25/h1-2,5-8,13,21H,3-4,9-12,14-15H2 ATTHVGBIVYJECI-UHFFFAOYSA-N 50001108 2-(3,4-Dichloro-phenyl)-1-(1-pyrrolidin-1-ylmethyl-3,4-dihydro-1H-isoquinolin-2-yl)-ethanone::2-(3,4-Dichloro-phenyl)-1-(1-pyrrolidin-1-ylmethyl-3,4-dihydro-1H-isoquinolin-2-yl)-ethanone;C4H6O6::2-(3,4-Dichloro-phenyl)-1-(1-pyrrolidin-1-ylmethyl-3,4-dihydro-1H-isoquinolin-2-yl)-ethanone;HCl::CHEMBL275025 Mu-type opioid receptor Cavia cutleri 30 ChEMBL 10.1021/jm00112a042 10.7270/Q2CV4GPX 1652025 Vecchietti, V; Clarke, GD; Colle, R; Giardina, G; Petrone, G; Sbacchi, M Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001108 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001108&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14726012 103915600 CHEMBL275025 ZINC13726265 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010713 Clc1ccc(CC(=O)N2CCc3ccsc3C2CN2CCCC2)cc1Cl InChI=1S/C20H22Cl2N2OS/c21-16-4-3-14(11-17(16)22)12-19(25)24-9-5-15-6-10-26-20(15)18(24)13-23-7-1-2-8-23/h3-4,6,10-11,18H,1-2,5,7-9,12-13H2 UFRFKPDRMYNUAU-UHFFFAOYSA-N 50007166 2-(3,4-Dichloro-phenyl)-1-(7-pyrrolidin-1-ylmethyl-4,7-dihydro-5H-thieno[2,3-c]pyridin-6-yl)-ethanone;HCl::CHEMBL88168 Mu-type opioid receptor Cavia cutleri 47 ChEMBL 10.1021/jm00112a042 10.7270/Q2CV4GPX 1652025 Vecchietti, V; Clarke, GD; Colle, R; Giardina, G; Petrone, G; Sbacchi, M Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007166 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007166&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9822764 103920449 CHEMBL88168 ZINC13823973 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010714 FC(F)(F)c1ccc(CC(=O)N2CCc3ccccc3[C@H]2CN2CCCC2)cc1 InChI=1S/C23H25F3N2O/c24-23(25,26)19-9-7-17(8-10-19)15-22(29)28-14-11-18-5-1-2-6-20(18)21(28)16-27-12-3-4-13-27/h1-2,5-10,21H,3-4,11-16H2/t21-/m1/s1 YOLQXHYBPFPWEI-OAQYLSRUSA-N 50453089 CHEMBL2114225 Mu-type opioid receptor Cavia cutleri 11 ChEMBL 10.1021/jm00112a042 10.7270/Q2CV4GPX 1652025 Vecchietti, V; Clarke, GD; Colle, R; Giardina, G; Petrone, G; Sbacchi, M Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453089 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453089&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10069687 225145851 CHEMBL2114225 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010715 Clc1ccc(CC(=O)N2CCCC[C@H]2CN2CCCC2)cc1Cl InChI=1S/C18H24Cl2N2O/c19-16-7-6-14(11-17(16)20)12-18(23)22-10-2-1-5-15(22)13-21-8-3-4-9-21/h6-7,11,15H,1-5,8-10,12-13H2/t15-/m0/s1 GHCCBWMZKJQGLS-HNNXBMFYSA-N 50007158 (S)-2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone(BRL 52537)::2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone::CHEMBL71294 Mu-type opioid receptor Cavia cutleri 1559 ChEMBL 10.1021/jm00112a042 10.7270/Q2CV4GPX 1652025 Vecchietti, V; Clarke, GD; Colle, R; Giardina, G; Petrone, G; Sbacchi, M Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007158&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603740 103920441 CHEMBL71294 ZINC02567733 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010716 CN(C)CC1N(CCc2ccccc12)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C20H22Cl2N2O.C4H6O6.C2H6O/c1-23(2)13-19-16-6-4-3-5-15(16)9-10-24(19)20(25)12-14-7-8-17(21)18(22)11-14;5-1(3(7)8)2(6)4(9)10;1-2-3/h3-8,11,19H,9-10,12-13H2,1-2H3;1-2,5-6H,(H,7,8)(H,9,10);3H,2H2,1H3 JWVNTYAIFVDODJ-UHFFFAOYSA-N 50453088 CHEMBL2114226 Mu-type opioid receptor Cavia cutleri 293 ChEMBL 10.1021/jm00112a042 10.7270/Q2CV4GPX 1652025 Vecchietti, V; Clarke, GD; Colle, R; Giardina, G; Petrone, G; Sbacchi, M Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453088 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453088&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71458085 225145850 CHEMBL2114226 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010719 Clc1ccc(CC(=O)N2CCc3sccc3C2CN2CCCCC2)cc1Cl InChI=1S/C21H24Cl2N2OS/c22-17-5-4-15(12-18(17)23)13-21(26)25-10-6-20-16(7-11-27-20)19(25)14-24-8-2-1-3-9-24/h4-5,7,11-12,19H,1-3,6,8-10,13-14H2 CFDUQHHQBATUFR-UHFFFAOYSA-N 50007165 2-(3,4-Dichloro-phenyl)-1-(4-piperidin-1-ylmethyl-6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)-ethanone;HCl::CHEMBL87010 Mu-type opioid receptor Cavia cutleri 445 ChEMBL 10.1021/jm00112a042 10.7270/Q2CV4GPX 1652025 Vecchietti, V; Clarke, GD; Colle, R; Giardina, G; Petrone, G; Sbacchi, M Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007165 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007165&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15697375 103920448 CHEMBL87010 ZINC03797738 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010721 Clc1ccc(CC(=O)N2CCc3c([nH]c4ccccc34)C2CN2CCCC2)cc1Cl InChI=1S/C24H25Cl2N3O/c25-19-8-7-16(13-20(19)26)14-23(30)29-12-9-18-17-5-1-2-6-21(17)27-24(18)22(29)15-28-10-3-4-11-28/h1-2,5-8,13,22,27H,3-4,9-12,14-15H2 SNEYMUAQCKBVHQ-UHFFFAOYSA-N 50007162 2-(3,4-Dichloro-phenyl)-1-(1-pyrrolidin-1-ylmethyl-1,3,4,9-tetrahydro-beta-carbolin-2-yl)-ethanone;HCl::CHEMBL329343 Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm00112a042 10.7270/Q2CV4GPX 1652025 Vecchietti, V; Clarke, GD; Colle, R; Giardina, G; Petrone, G; Sbacchi, M Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007162 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007162&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15697380 103920445 CHEMBL329343 ZINC13823981 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010731 FC(F)(F)c1ccc(CC(=O)N2CCc3ccccc3C2CN2CCCCC2)cc1 InChI=1S/C24H27F3N2O/c25-24(26,27)20-10-8-18(9-11-20)16-23(30)29-15-12-19-6-2-3-7-21(19)22(29)17-28-13-4-1-5-14-28/h2-3,6-11,22H,1,4-5,12-17H2 FHVYBRJOURPHKM-UHFFFAOYSA-N 50007157 (-)-1-(1-Piperidin-1-ylmethyl-3,4-dihydro-1H-isoquinolin-2-yl)-2-(4-trifluoromethyl-phenyl)-ethanone;C4H6O6::CHEMBL88393 Mu-type opioid receptor Cavia cutleri 231 ChEMBL 10.1021/jm00112a042 10.7270/Q2CV4GPX 1652025 Vecchietti, V; Clarke, GD; Colle, R; Giardina, G; Petrone, G; Sbacchi, M Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007157 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007157&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15697369 103920440 CHEMBL88393 ZINC26579191 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010734 FC(F)(F)c1ccc(CC(=O)N2CCc3sccc3C2CN2CCCCC2)cc1 InChI=1S/C22H25F3N2OS/c23-22(24,25)17-6-4-16(5-7-17)14-21(28)27-12-8-20-18(9-13-29-20)19(27)15-26-10-2-1-3-11-26/h4-7,9,13,19H,1-3,8,10-12,14-15H2 AWRJQLFBUIUNHN-UHFFFAOYSA-N 50007167 1-(4-Piperidin-1-ylmethyl-6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)-2-(4-trifluoromethyl-phenyl)-ethanone;C4H6O6::CHEMBL329114 Mu-type opioid receptor Cavia cutleri 420 ChEMBL 10.1021/jm00112a042 10.7270/Q2CV4GPX 1652025 Vecchietti, V; Clarke, GD; Colle, R; Giardina, G; Petrone, G; Sbacchi, M Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007167 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007167&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15697378 103920450 CHEMBL329114 ZINC03797740 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010776 N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](Cc2ccccc2)NC(=O)CNC1=O)C(N)=O InChI=1S/C26H32N6O5S2/c27-18(11-16-7-3-1-4-8-16)24(35)32-21-15-39-38-14-20(23(28)34)31-26(37)19(12-17-9-5-2-6-10-17)30-22(33)13-29-25(21)36/h1-10,18-21H,11-15,27H2,(H2,28,34)(H,29,36)(H,30,33)(H,31,37)(H,32,35)/t18-,19+,20-,21-/m0/s1 VBQUWIWZYQXBPT-WOZUAGRISA-N 50083737 13-((S)-2-Amino-3-phenyl-propionylamino)-7-benzyl-6,12-di(R)-oxo-9-oxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid amide::CHEMBL432238 Mu-type opioid receptor Cavia cutleri 42 ChEMBL 10.1016/s0960-894x(99)00625-3 10.7270/Q2P55MQ9 10617088 Burden, JE; Davis, P; Porreca, F; Spatola, AF University of Louisville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083737&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44343358 103983338 CHEMBL432238 ZINC27098321 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010777 CC1(C)SSC[C@H](NC(=O)[C@@H](N)Cc2ccccc2)C(=O)N[C@H](Cc2ccccc2)C(=O)N[C@@H]1C(N)=O InChI=1S/C26H33N5O4S2/c1-26(2)21(22(28)32)31-24(34)19(14-17-11-7-4-8-12-17)29-25(35)20(15-36-37-26)30-23(33)18(27)13-16-9-5-3-6-10-16/h3-12,18-21H,13-15,27H2,1-2H3,(H2,28,32)(H,29,35)(H,30,33)(H,31,34)/t18-,19+,20-,21+/m0/s1 IYVHIOLNKLWIGU-JSXRDJHFSA-N 50083732 (6R,9R)-10-((S)-2-Amino-3-phenyl-propionylamino)-7-benzyl-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid amide::CHEMBL324390 Mu-type opioid receptor Cavia cutleri 9.1 ChEMBL 10.1016/s0960-894x(99)00625-3 10.7270/Q2P55MQ9 10617088 Burden, JE; Davis, P; Porreca, F; Spatola, AF University of Louisville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083732 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083732&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44343030 103983333 CHEMBL324390 ZINC27091390 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010785 N[C@H](Cc1ccccc1)C(=O)N[C@@H]1CCCCNC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O InChI=1S/C35H40N6O5/c36-27(18-22-8-2-1-3-9-22)32(43)39-29-12-6-7-17-37-33(44)31(21-25-20-24-10-4-5-11-28(24)38-25)41-35(46)30(40-34(29)45)19-23-13-15-26(42)16-14-23/h1-5,8-11,13-16,20,27,29-31,38,42H,6-7,12,17-19,21,36H2,(H,37,44)(H,39,43)(H,40,45)(H,41,46)/t27-,29-,30+,31+/m1/s1 RDORPONJAXSNEH-JIBNBMRDSA-N 50083733 2-Amino-N-[(S)-6-(4-hydroxy-benzyl)-3-(1H-indol-2-ylmethyl)-2,5,8-trioxo-1,4,7triaza-cyclotridec-9-yl]-3-phenyl-propionamide::CHEMBL2370486 Mu-type opioid receptor Cavia cutleri 627 ChEMBL 10.1016/s0960-894x(99)00625-3 10.7270/Q2P55MQ9 10617088 Burden, JE; Davis, P; Porreca, F; Spatola, AF University of Louisville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083733 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083733&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73354566 103983334 CHEMBL2370486 ZINC44201705 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010787 C[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CCCCNC1=O)NC(=O)[C@H](N)Cc1ccccc1 InChI=1S/C27H35N5O5/c1-17-24(34)29-14-6-5-9-22(31-25(35)21(28)15-18-7-3-2-4-8-18)26(36)32-23(27(37)30-17)16-19-10-12-20(33)13-11-19/h2-4,7-8,10-13,17,21-23,33H,5-6,9,14-16,28H2,1H3,(H,29,34)(H,30,37)(H,31,35)(H,32,36)/t17-,21+,22+,23-/m0/s1 WTSQRSCMGUSYGR-VAFVZNMKSA-N 50083735 (R)-2-Amino-N-[(R)-6-(4-hydroxy-benzyl)-3-methyl-2,5,8-trioxo-1,4,7triaza-cyclotridec-9-yl]-3-phenyl-propionamide::CHEMBL2370484 Mu-type opioid receptor Cavia cutleri 1827 ChEMBL 10.1016/s0960-894x(99)00625-3 10.7270/Q2P55MQ9 10617088 Burden, JE; Davis, P; Porreca, F; Spatola, AF University of Louisville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083735&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73345475 103983336 CHEMBL2370484 ZINC27085365 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010788 C[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](CCCCNC1=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C27H35N5O5/c1-17-24(34)29-14-6-5-9-22(31-25(35)21(28)15-19-10-12-20(33)13-11-19)26(36)32-23(27(37)30-17)16-18-7-3-2-4-8-18/h2-4,7-8,10-13,17,21-23,33H,5-6,9,14-16,28H2,1H3,(H,29,34)(H,30,37)(H,31,35)(H,32,36)/t17-,21-,22+,23-/m0/s1 SOWBCHKRRDXSQT-QMZRJTEUSA-N 50083734 2-Amino-N-[(R)-6-(4-hydroxy-benzyl)-3-methyl-2,5,8-trioxo-1,4,7triaza-cyclotridec-9-yl]-3-phenyl-propionamide::CHEMBL2370485 Mu-type opioid receptor Cavia cutleri 0.110000 ChEMBL 10.1016/s0960-894x(99)00625-3 10.7270/Q2P55MQ9 10617088 Burden, JE; Davis, P; Porreca, F; Spatola, AF University of Louisville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083734&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73351576 103983335 CHEMBL2370485 ZINC40479633 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010789 N[C@@H](Cc1ccccc1)C(=O)N[C@@H]1CCCCNC(=O)[C@H](Cc2cc3ccccc3[nH]2)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O InChI=1S/C35H40N6O5/c36-27(18-22-8-2-1-3-9-22)32(43)39-29-12-6-7-17-37-33(44)31(21-25-20-24-10-4-5-11-28(24)38-25)41-35(46)30(40-34(29)45)19-23-13-15-26(42)16-14-23/h1-5,8-11,13-16,20,27,29-31,38,42H,6-7,12,17-19,21,36H2,(H,37,44)(H,39,43)(H,40,45)(H,41,46)/t27-,29+,30-,31-/m0/s1 RDORPONJAXSNEH-LYXINOJLSA-N 50083730 (R)-2-Amino-N-[(S)-6-(4-hydroxy-benzyl)-3-(1H-indol-2-ylmethyl)-2,5,8-trioxo-1,4,7triaza-cyclotridec-9-yl]-3-phenyl-propionamide::CHEMBL2370482 Mu-type opioid receptor Cavia cutleri 18 ChEMBL 10.1016/s0960-894x(99)00625-3 10.7270/Q2P55MQ9 10617088 Burden, JE; Davis, P; Porreca, F; Spatola, AF University of Louisville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083730 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083730&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73345473 103983331 CHEMBL2370482 ZINC27083928 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010790 C[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CCCCNC1=O)NC(=O)[C@@H](N)Cc1ccccc1 InChI=1S/C27H35N5O5/c1-17-24(34)29-14-6-5-9-22(31-25(35)21(28)15-18-7-3-2-4-8-18)26(36)32-23(27(37)30-17)16-19-10-12-20(33)13-11-19/h2-4,7-8,10-13,17,21-23,33H,5-6,9,14-16,28H2,1H3,(H,29,34)(H,30,37)(H,31,35)(H,32,36)/t17-,21-,22+,23-/m0/s1 WTSQRSCMGUSYGR-QMZRJTEUSA-N 50083729 2-Amino-N-((R)-6-benzyl-3-methyl-2,5,8-trioxo-1,4,7triaza-cyclotridec-9-yl)-3-(4-hydroxy-phenyl)-propionamide::CHEMBL2370483 Mu-type opioid receptor Cavia cutleri 30 ChEMBL 10.1016/s0960-894x(99)00625-3 10.7270/Q2P55MQ9 10617088 Burden, JE; Davis, P; Porreca, F; Spatola, AF University of Louisville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083729 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083729&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73345474 103983330 CHEMBL2370483 ZINC40701161 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010792 N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](Cc2ccc(cc2)[N+]([O-])=O)NC(=O)CNC1=O)C(N)=O InChI=1S/C26H31N7O7S2/c27-18(10-15-4-2-1-3-5-15)24(36)32-21-14-42-41-13-20(23(28)35)31-26(38)19(30-22(34)12-29-25(21)37)11-16-6-8-17(9-7-16)33(39)40/h1-9,18-21H,10-14,27H2,(H2,28,35)(H,29,37)(H,30,34)(H,31,38)(H,32,36)/t18-,19+,20-,21-/m0/s1 SKQRZVBGKOLTKG-WOZUAGRISA-N 50083736 13-((S)-2-Amino-3-phenyl-propionylamino)-7-(4-nitro-benzyl)-6,12-di(R)-oxo-9-oxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid amide::CHEMBL113782 Mu-type opioid receptor Cavia cutleri 13 ChEMBL 10.1016/s0960-894x(99)00625-3 10.7270/Q2P55MQ9 10617088 Burden, JE; Davis, P; Porreca, F; Spatola, AF University of Louisville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083736 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083736&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44343015 103983337 CHEMBL113782 ZINC27085372 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50012957 C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@@]1(C)CN2CC1CC1 InChI=1S/C17H23NO/c1-11-16-7-13-5-6-14(19)8-15(13)17(11,2)10-18(16)9-12-3-4-12/h5-6,8,11-12,16,19H,3-4,7,9-10H2,1-2H3/t11-,16+,17+/m1/s1 LSQSRZOMUOOWDV-NVGVWMPQSA-N 50001040 6,11-Dimethyl-3-(3-methyl-butyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL2021605 Mu-type opioid receptor Cavia cutleri 360 ChEMBL 10.1016/s0960-894x(99)00670-8 10.7270/Q2571CH7 10673107 Wentland, MP; Xu, G; Cioffi, CL; Ye, Y; Duan, W; Cohen, DJ; Colasurdo, AM; Bidlack, JM Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001040 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001040&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 70696030 103915573 CHEMBL2021605 ZINC13726124 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50014111 C[C@H]1[C@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CC1CC1 InChI=1S/C18H25NO/c1-12-17-9-14-5-6-15(20)10-16(14)18(12,2)7-8-19(17)11-13-3-4-13/h5-6,10,12-13,17,20H,3-4,7-9,11H2,1-2H3/t12-,17+,18+/m0/s1 YQYVFVRQLZMJKJ-JBBXEZCESA-N 50001023 (2R,6R,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL56585::Cyclazocine::US10231963, Table B.9::US10736890, Compound TABLE B.9::US11534436, Compound Table B.9::US9656961, Example 00126 Mu-type opioid receptor Cavia cutleri 0.320000 ChEMBL 10.1016/s0960-894x(01)00278-5 10.7270/Q2TM7BNK 11425545 Wentland, MP; Lou, R; Dehnhardt, CM; Duan, W; Cohen, DJ; Bidlack, JM Pharmacia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001023&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3037926 103915556 CHEMBL56585 ZINC03830613 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50014112 CC1C2Cc3ccc(cc3C1(C)CCN2CC1CC1)C(N)=O InChI=1S/C19H26N2O/c1-12-17-10-14-5-6-15(18(20)22)9-16(14)19(12,2)7-8-21(17)11-13-3-4-13/h5-6,9,12-13,17H,3-4,7-8,10-11H2,1-2H3,(H2,20,22) FAVQVALXVLMHLE-UHFFFAOYSA-N 50101160 3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid amide::CHEMBL297428 Mu-type opioid receptor Cavia cutleri 0.410000 ChEMBL 10.1016/s0960-894x(01)00278-5 10.7270/Q2TM7BNK 11425545 Wentland, MP; Lou, R; Dehnhardt, CM; Duan, W; Cohen, DJ; Bidlack, JM Pharmacia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101160 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101160&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9839245 103997855 CHEMBL297428 ZINC33980697 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50014118 CN1CC[C@@]23C4Oc5c2c(C[C@@H]1[C@@H]3C=CC4O)ccc5C(N)=O InChI=1S/C18H20N2O3/c1-20-7-6-18-11-4-5-13(21)16(18)23-15-10(17(19)22)3-2-9(14(15)18)8-12(11)20/h2-5,11-13,16,21H,6-8H2,1H3,(H2,19,22)/t11-,12+,13?,16?,18-/m0/s1 IBOHPBGICFUISW-OOGGRKRCSA-N 50101158 14-hydroxy-4-methyl-(1S,5R,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18),15-tetraene-10-carboxamide::CHEMBL47512 Mu-type opioid receptor Cavia cutleri 34 ChEMBL 10.1016/s0960-894x(01)00278-5 10.7270/Q2TM7BNK 11425545 Wentland, MP; Lou, R; Dehnhardt, CM; Duan, W; Cohen, DJ; Bidlack, JM Pharmacia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101158&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44292986 103997853 CHEMBL47512 ZINC36221068 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50014119 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 0.880000 ChEMBL 10.1016/s0960-894x(01)00278-5 10.7270/Q2TM7BNK 11425545 Wentland, MP; Lou, R; Dehnhardt, CM; Duan, W; Cohen, DJ; Bidlack, JM Pharmacia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50014125 CN(C)C(=O)c1ccc2C[C@@H]3[C@@H]4C=CC(O)C5Oc1c2[C@]45CCN3C InChI=1S/C20H24N2O3/c1-21(2)19(24)12-5-4-11-10-14-13-6-7-15(23)18-20(13,8-9-22(14)3)16(11)17(12)25-18/h4-7,13-15,18,23H,8-10H2,1-3H3/t13-,14+,15?,18?,20-/m0/s1 TXXJZUWLHUOEHJ-XCFVLRLUSA-N 50101159 4,10N,10N-trimethyl-14-hydroxy-(1S,5R,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18),15-tetraene-10-carboxamide::CHEMBL50386 Mu-type opioid receptor Cavia cutleri 5800 ChEMBL 10.1016/s0960-894x(01)00278-5 10.7270/Q2TM7BNK 11425545 Wentland, MP; Lou, R; Dehnhardt, CM; Duan, W; Cohen, DJ; Bidlack, JM Pharmacia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101159 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101159&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44292682 103997854 CHEMBL50386 ZINC29417346 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50014129 CNC(=O)c1ccc2C[C@@H]3[C@@H]4C=CC(O)C5Oc1c2[C@]45CCN3C InChI=1S/C19H22N2O3/c1-20-18(23)11-4-3-10-9-13-12-5-6-14(22)17-19(12,7-8-21(13)2)15(10)16(11)24-17/h3-6,12-14,17,22H,7-9H2,1-2H3,(H,20,23)/t12-,13+,14?,17?,19-/m0/s1 HDZZVBSQIZPFRO-LLSMSMPGSA-N 50101162 4,10N-dimethyl-14-hydroxy-(1S,5R,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18),15-tetraene-10-carboxamide::CHEMBL49029 Mu-type opioid receptor Cavia cutleri 440 ChEMBL 10.1016/s0960-894x(01)00278-5 10.7270/Q2TM7BNK 11425545 Wentland, MP; Lou, R; Dehnhardt, CM; Duan, W; Cohen, DJ; Bidlack, JM Pharmacia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101162 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101162&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44292684 103997857 CHEMBL49029 ZINC29417365 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013035 CC(C)Nc1ccc2CC3[C@H](C)[C@](C)(CCN3CC3CC3)c2c1 InChI=1S/C21H32N2/c1-14(2)22-18-8-7-17-11-20-15(3)21(4,19(17)12-18)9-10-23(20)13-16-5-6-16/h7-8,12,14-16,20,22H,5-6,9-11,13H2,1-4H3/t15-,20?,21-/m0/s1 MJVYKOPUBZDGOV-FRIMRSDBSA-N 50085031 ((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-isopropyl-amine::(3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-isopropyl-amine::CHEMBL55434 Mu-type opioid receptor Cavia cutleri 240 ChEMBL 10.1016/s0960-894x(99)00670-8 10.7270/Q2571CH7 10673107 Wentland, MP; Xu, G; Cioffi, CL; Ye, Y; Duan, W; Cohen, DJ; Colasurdo, AM; Bidlack, JM Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085031&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44298240 103984514 CHEMBL55434 ZINC29550081 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013038 CCNc1ccc2CC3[C@H](C)[C@](C)(CCN3CC3CC3)c2c1 InChI=1S/C20H30N2/c1-4-21-17-8-7-16-11-19-14(2)20(3,18(16)12-17)9-10-22(19)13-15-5-6-15/h7-8,12,14-15,19,21H,4-6,9-11,13H2,1-3H3/t14-,19?,20-/m0/s1 OLPQWIWZIFECJG-JUJMCKSGSA-N 50085028 ((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-ethyl-amine::(3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-ethyl-amine::CHEMBL55851 Mu-type opioid receptor Cavia cutleri 5.1 ChEMBL 10.1016/s0960-894x(99)00670-8 10.7270/Q2571CH7 10673107 Wentland, MP; Xu, G; Cioffi, CL; Ye, Y; Duan, W; Cohen, DJ; Colasurdo, AM; Bidlack, JM Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085028&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44298198 103984511 CHEMBL55851 ZINC29550565 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013039 C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)N(C)Cc1ccccc1 InChI=1S/C26H34N2/c1-19-25-15-22-11-12-23(27(3)17-20-7-5-4-6-8-20)16-24(22)26(19,2)13-14-28(25)18-21-9-10-21/h4-8,11-12,16,19,21,25H,9-10,13-15,17-18H2,1-3H3/t19-,25?,26-/m0/s1 OHQXZYAOUKKRAK-JKEZHHNBSA-N 50085030 Benzyl-((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-methyl-amine::Benzyl-(3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-methyl-amine::CHEMBL293951 Mu-type opioid receptor Cavia cutleri 56 ChEMBL 10.1016/s0960-894x(99)00670-8 10.7270/Q2571CH7 10673107 Wentland, MP; Xu, G; Cioffi, CL; Ye, Y; Duan, W; Cohen, DJ; Colasurdo, AM; Bidlack, JM Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085030&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44298201 103984513 CHEMBL293951 ZINC29548653 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013040 C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)N1CCN(C)CC1 InChI=1S/C23H35N3/c1-17-22-14-19-6-7-20(25-12-10-24(3)11-13-25)15-21(19)23(17,2)8-9-26(22)16-18-4-5-18/h6-7,15,17-18,22H,4-5,8-14,16H2,1-3H3/t17-,22?,23-/m0/s1 DQRUYAPFAYHFFI-XHLMSTEBSA-N 50085026 (6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-8-(4-methyl-piperazin-1-yl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::3-Cyclopropylmethyl-6,11-dimethyl-8-(4-methyl-piperazin-1-yl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::CHEMBL55392 Mu-type opioid receptor Cavia cutleri 21 ChEMBL 10.1016/s0960-894x(99)00670-8 10.7270/Q2571CH7 10673107 Wentland, MP; Xu, G; Cioffi, CL; Ye, Y; Duan, W; Cohen, DJ; Colasurdo, AM; Bidlack, JM Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085026&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44298202 103984509 CHEMBL55392 ZINC29548656 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013044 C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)N1CCOCC1 InChI=1S/C22H32N2O/c1-16-21-13-18-5-6-19(23-9-11-25-12-10-23)14-20(18)22(16,2)7-8-24(21)15-17-3-4-17/h5-6,14,16-17,21H,3-4,7-13,15H2,1-2H3/t16-,21?,22-/m0/s1 FCUBDHJZNYQBJC-URJRECBDSA-N 50085027 (6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-8-morpholin-4-yl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::3-Cyclopropylmethyl-6,11-dimethyl-8-morpholin-4-yl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::CHEMBL55248 Mu-type opioid receptor Cavia cutleri 650 ChEMBL 10.1016/s0960-894x(99)00670-8 10.7270/Q2571CH7 10673107 Wentland, MP; Xu, G; Cioffi, CL; Ye, Y; Duan, W; Cohen, DJ; Colasurdo, AM; Bidlack, JM Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085027&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44298203 103984510 CHEMBL55248 ZINC29548924 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013052 C[C@H]1[C@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CC1CC1 InChI=1S/C18H25NO/c1-12-17-9-14-5-6-15(20)10-16(14)18(12,2)7-8-19(17)11-13-3-4-13/h5-6,10,12-13,17,20H,3-4,7-9,11H2,1-2H3/t12-,17+,18+/m0/s1 YQYVFVRQLZMJKJ-JBBXEZCESA-N 50001023 (2R,6R,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL56585::Cyclazocine::US10231963, Table B.9::US10736890, Compound TABLE B.9::US11534436, Compound Table B.9::US9656961, Example 00126 Mu-type opioid receptor Cavia cutleri 0.100000 ChEMBL 10.1016/s0960-894x(99)00670-8 10.7270/Q2571CH7 10673107 Wentland, MP; Xu, G; Cioffi, CL; Ye, Y; Duan, W; Cohen, DJ; Colasurdo, AM; Bidlack, JM Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001023&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3037926 103915556 CHEMBL56585 ZINC03830613 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013073 CCCCC(=N)NCc1ccc2[nH]c3C4Oc5c6c(CC7N(CC8CC8)CCC46[C@@]7(O)Cc3c2c1)ccc5O InChI=1S/C32H38N4O3/c1-2-3-4-26(33)34-16-19-7-9-23-21(13-19)22-15-32(38)25-14-20-8-10-24(37)29-27(20)31(32,30(39-29)28(22)35-23)11-12-36(25)17-18-5-6-18/h7-10,13,18,25,30,35,37-38H,2-6,11-12,14-17H2,1H3,(H2,33,34)/t25?,30?,31?,32-/m1/s1 LHABVQRHEYQPMS-FHLQZRSLSA-N 50092998 CHEMBL72786::Derivative of Natrindole Mu-type opioid receptor Cavia cutleri 3.5 ChEMBL 10.1016/s0960-894x(00)00433-9 10.7270/Q2WS8TRF 11055333 Jales, AR; Husbands, SM; Lewis, JW University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092998 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092998&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44311978 103991017 CHEMBL72786 ZINC36221082 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50014109 NC(=O)c1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C21H24N2O4/c22-19(25)13-4-3-12-9-15-21(26)6-5-14(24)18-20(21,16(12)17(13)27-18)7-8-23(15)10-11-1-2-11/h3-4,11,15,18,26H,1-2,5-10H2,(H2,22,25)/t15-,18+,20+,21-/m1/s1 QAICPHMNUHNDMC-WUHBCXKYSA-N 50128411 3-desoxy-3-carboxamidonaltrexone::4-cyclopropylmethyl-17-hydroxy-14-oxo-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-triene-10-carboxamide::CHEMBL56695 Mu-type opioid receptor Cavia cutleri 1.9 ChEMBL 10.1016/s0960-894x(01)00278-5 10.7270/Q2TM7BNK 11425545 Wentland, MP; Lou, R; Dehnhardt, CM; Duan, W; Cohen, DJ; Bidlack, JM Pharmacia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128411 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128411&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10021946 104020176 CHEMBL56695 ZINC13490125 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50014110 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1 DQCKKXVULJGBQN-XFWGSAIBSA-N 60212 (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::MLS000069607::NALTREXONE HYDROCHLORIDE::SMR000058767::US10988481, Compound NTX::US9107954, naltrexone::cid_5485201 Mu-type opioid receptor Cavia cutleri 0.170000 ChEMBL 10.1016/s0960-894x(01)00278-5 10.7270/Q2TM7BNK 11425545 Wentland, MP; Lou, R; Dehnhardt, CM; Duan, W; Cohen, DJ; Bidlack, JM Pharmacia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60212&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5360515 252639834 DB00704 C07253 ZINC00001773 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50011227 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@]31CC[C@]42OC(C)(C)C(C)(C)[C@@H]2C1)ccc5O InChI=1S/C25H33NO3/c1-21(2)16-13-23-8-9-25(16,29-22(21,3)4)20-24(23)10-11-26(5)17(23)12-14-6-7-15(27)19(28-20)18(14)24/h6-7,16-17,20,27H,8-13H2,1-5H3/t16-,17?,20+,23+,24-,25+/m0/s1 FTOZVQKYOSPMCR-KHYIZFIASA-N 50451004 CHEMBL2110315 Mu-type opioid receptor Cavia cutleri 0.600000 ChEMBL 10.1016/s0960-894x(99)00085-2 10.7270/Q2FT8MJK 10206545 Husbands, SM; Breeden, SW; Grivas, K; Lewis, JW University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50451004 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50451004&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 70693567 225145228 CHEMBL2110315 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50011239 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@]31CC[C@]42OC(C)(C)C(C)(C)[C@H]2C1)ccc5O InChI=1S/C25H33NO3/c1-21(2)16-13-23-8-9-25(16,29-22(21,3)4)20-24(23)10-11-26(5)17(23)12-14-6-7-15(27)19(28-20)18(14)24/h6-7,16-17,20,27H,8-13H2,1-5H3/t16-,17?,20-,23-,24+,25-/m1/s1 FTOZVQKYOSPMCR-JWZBYVFRSA-N 50451002 CHEMBL2110199 Mu-type opioid receptor Cavia cutleri 0.200000 ChEMBL 10.1016/s0960-894x(99)00085-2 10.7270/Q2FT8MJK 10206545 Husbands, SM; Breeden, SW; Grivas, K; Lewis, JW University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50451002 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50451002&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 70691453 225145227 CHEMBL2110199 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013375 CCN(CC)CC1CCCCN1C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C18H26Cl2N2O/c1-3-21(4-2)13-15-7-5-6-10-22(15)18(23)12-14-8-9-16(19)17(20)11-14/h8-9,11,15H,3-7,10,12-13H2,1-2H3 ZSNPTGYVRMEOHR-UHFFFAOYSA-N 50008899 2-(3,4-Dichloro-phenyl)-1-(2-diethylaminomethyl-piperidin-1-yl)-ethanone(HCl)::CHEMBL433849 Mu-type opioid receptor Cavia cutleri 5000 ChEMBL 10.1021/jm00105a061 10.7270/Q23777N1 1846921 Vecchietti, V; Giordani, A; Giardina, G; Colle, R; Clarke, GD Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008899 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008899&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14810954 103922000 CHEMBL433849 ZINC27328534 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013377 CN1CCCC1C1CCCCN1C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C18H24Cl2N2O/c1-21-9-4-6-16(21)17-5-2-3-10-22(17)18(23)12-13-7-8-14(19)15(20)11-13/h7-8,11,16-17H,2-6,9-10,12H2,1H3 UOAOMCIHXQMCHQ-UHFFFAOYSA-N 50008888 (threo)2-(3,4-Dichloro-phenyl)-1-[2-(1-methyl-pyrrolidin-2-yl)-piperidin-1-yl]-ethanone(HCl)::2-(3,4-Dichloro-phenyl)-1-[2-(1-methyl-pyrrolidin-2-yl)-piperidin-1-yl]-ethanone(HCl)::CHEMBL130272 Mu-type opioid receptor Cavia cutleri 464 ChEMBL 10.1021/jm00105a061 10.7270/Q23777N1 1846921 Vecchietti, V; Giordani, A; Giardina, G; Colle, R; Clarke, GD Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008888&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14810996 103921989 CHEMBL130272 ZINC26260850 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013378 Clc1ccc(CC(=O)N2CCCCC2CN2CCCC2)cc1 InChI=1S/C18H25ClN2O/c19-16-8-6-15(7-9-16)13-18(22)21-12-2-1-5-17(21)14-20-10-3-4-11-20/h6-9,17H,1-5,10-14H2 WHXQHLJEASVPJJ-UHFFFAOYSA-N 50008892 2-(4-Chloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone(HCl)::CHEMBL128766 Mu-type opioid receptor Cavia cutleri 5910 ChEMBL 10.1021/jm00105a061 10.7270/Q23777N1 1846921 Vecchietti, V; Giordani, A; Giardina, G; Colle, R; Clarke, GD Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008892 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008892&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14810963 103921993 CHEMBL128766 ZINC13861041 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013385 Clc1ccc(CC(=O)N2CCCC[C@H]2CN2CCCC2)cc1Cl InChI=1S/C18H24Cl2N2O/c19-16-7-6-14(11-17(16)20)12-18(23)22-10-2-1-5-15(22)13-21-8-3-4-9-21/h6-7,11,15H,1-5,8-10,12-13H2/t15-/m0/s1 GHCCBWMZKJQGLS-HNNXBMFYSA-N 50007158 (S)-2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone(BRL 52537)::2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone::CHEMBL71294 Mu-type opioid receptor Cavia cutleri 1560 ChEMBL 10.1021/jm00105a061 10.7270/Q23777N1 1846921 Vecchietti, V; Giordani, A; Giardina, G; Colle, R; Clarke, GD Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007158&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603740 103920441 CHEMBL71294 ZINC02567733 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013389 Brc1ccc(CC(=O)N2CCCCC2CN2CCCC2)cc1 InChI=1S/C18H25BrN2O/c19-16-8-6-15(7-9-16)13-18(22)21-12-2-1-5-17(21)14-20-10-3-4-11-20/h6-9,17H,1-5,10-14H2 FQMJNNUMEYMJCW-UHFFFAOYSA-N 50008897 2-(4-Bromo-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone(HCl)::CHEMBL130125 Mu-type opioid receptor Cavia cutleri 2980 ChEMBL 10.1021/jm00105a061 10.7270/Q23777N1 1846921 Vecchietti, V; Giordani, A; Giardina, G; Colle, R; Clarke, GD Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008897 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008897&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14810967 103921998 CHEMBL130125 ZINC13861044 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013392 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 3.3 ChEMBL 10.1021/jm00105a061 10.7270/Q23777N1 1846921 Vecchietti, V; Giordani, A; Giardina, G; Colle, R; Clarke, GD Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013395 CN(C)CC1CCCCN1C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C16H22Cl2N2O/c1-19(2)11-13-5-3-4-8-20(13)16(21)10-12-6-7-14(17)15(18)9-12/h6-7,9,13H,3-5,8,10-11H2,1-2H3 PROCBUWEYFCOPD-UHFFFAOYSA-N 50000267 2-(3,4-Dichloro-phenyl)-1-(2-dimethylaminomethyl-piperidin-1-yl)-ethanone::2-(3,4-Dichloro-phenyl)-1-(2-dimethylaminomethyl-piperidin-1-yl)-ethanone(HCl)::CHEMBL339552 Mu-type opioid receptor Cavia cutleri 3050 ChEMBL 10.1021/jm00105a061 10.7270/Q23777N1 1846921 Vecchietti, V; Giordani, A; Giardina, G; Colle, R; Clarke, GD Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000267 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000267&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14810949 103914874 CHEMBL339552 ZINC13449219 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013396 Cc1ccc(CC(=O)N2CCCCC2CN2CCCC2)cc1C InChI=1S/C20H30N2O/c1-16-8-9-18(13-17(16)2)14-20(23)22-12-4-3-7-19(22)15-21-10-5-6-11-21/h8-9,13,19H,3-7,10-12,14-15H2,1-2H3 XDPGWBBLNRCBBD-UHFFFAOYSA-N 50008893 2-(3,4-Dimethyl-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone(HCl)::CHEMBL435391 Mu-type opioid receptor Cavia cutleri 5310 ChEMBL 10.1021/jm00105a061 10.7270/Q23777N1 1846921 Vecchietti, V; Giordani, A; Giardina, G; Colle, R; Clarke, GD Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008893 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008893&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14810979 103921994 CHEMBL435391 ZINC13861051 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013398 CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C19H26Cl2N2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17-,18-/m1/s1 VQLPLYSROCPWFF-QZTJIDSGSA-N 50000296 CHEMBL441765::CHEMBL482811::U-50488H::US11492374, ID 1 Mu-type opioid receptor Cavia cutleri 616 ChEMBL 10.1021/jm00105a061 10.7270/Q23777N1 1846921 Vecchietti, V; Giordani, A; Giardina, G; Colle, R; Clarke, GD Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000296&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036289 103914903 73358 CHEMBL482811CHEMBL441765 1654 C11796 ZINC00643032 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013401 FC(F)(F)c1ccc(CC(=O)N2CCCCC2CN2CCCC2)cc1 InChI=1S/C19H25F3N2O/c20-19(21,22)16-8-6-15(7-9-16)13-18(25)24-12-2-1-5-17(24)14-23-10-3-4-11-23/h6-9,17H,1-5,10-14H2 RFTWMVGLYKJUCZ-UHFFFAOYSA-N 50008895 1-(2-Pyrrolidin-1-ylmethyl-piperidin-1-yl)-2-(4-trifluoromethyl-phenyl)-ethanone(HCl)::CHEMBL128542 Mu-type opioid receptor Cavia cutleri 2340 ChEMBL 10.1021/jm00105a061 10.7270/Q23777N1 1846921 Vecchietti, V; Giordani, A; Giardina, G; Colle, R; Clarke, GD Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008895 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008895&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14810960 103921996 CHEMBL128542 ZINC00596666 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013402 Clc1ccc(CC(=O)N2CCCCC2CN2CCCC2)cc1Cl InChI=1S/C18H24Cl2N2O/c19-16-7-6-14(11-17(16)20)12-18(23)22-10-2-1-5-15(22)13-21-8-3-4-9-21/h6-7,11,15H,1-5,8-10,12-13H2 GHCCBWMZKJQGLS-UHFFFAOYSA-N 50000287 2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone::2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone(HCl)::CHEMBL128444 Mu-type opioid receptor Cavia cutleri 1860 ChEMBL 10.1021/jm00105a061 10.7270/Q23777N1 1846921 Vecchietti, V; Giordani, A; Giardina, G; Colle, R; Clarke, GD Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000287 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000287&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5244802 103914894 CHEMBL128444 ZINC03995684 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013406 Cc1ccc(CC(=O)N2CCCCC2CN2CCCC2)cc1 InChI=1S/C19H28N2O/c1-16-7-9-17(10-8-16)14-19(22)21-13-3-2-6-18(21)15-20-11-4-5-12-20/h7-10,18H,2-6,11-15H2,1H3 MTLKCRAUDOTIDJ-UHFFFAOYSA-N 50008894 1-(2-Pyrrolidin-1-ylmethyl-piperidin-1-yl)-2-p-tolyl-ethanone(HCl)::CHEMBL337841 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm00105a061 10.7270/Q23777N1 1846921 Vecchietti, V; Giordani, A; Giardina, G; Colle, R; Clarke, GD Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008894 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008894&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14810977 103921995 CHEMBL337841 ZINC13861049 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013407 CN(C)C[C@@H]1CCCCN1C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C16H22Cl2N2O/c1-19(2)11-13-5-3-4-8-20(13)16(21)10-12-6-7-14(17)15(18)9-12/h6-7,9,13H,3-5,8,10-11H2,1-2H3/t13-/m0/s1 PROCBUWEYFCOPD-ZDUSSCGKSA-N 50452995 CHEMBL2111856 Mu-type opioid receptor Cavia cutleri 2160 ChEMBL 10.1021/jm00105a061 10.7270/Q23777N1 1846921 Vecchietti, V; Giordani, A; Giardina, G; Colle, R; Clarke, GD Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452995 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452995&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14810952 225145803 CHEMBL2111856 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013411 Fc1ccc(CC(=O)N2CCCCC2CN2CCCC2)cc1 InChI=1S/C18H25FN2O/c19-16-8-6-15(7-9-16)13-18(22)21-12-2-1-5-17(21)14-20-10-3-4-11-20/h6-9,17H,1-5,10-14H2 XJROJAHLFHCPAF-UHFFFAOYSA-N 50008891 2-(4-Fluoro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone(HCl)::CHEMBL128796 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm00105a061 10.7270/Q23777N1 1846921 Vecchietti, V; Giordani, A; Giardina, G; Colle, R; Clarke, GD Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008891 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008891&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14810965 103921992 CHEMBL128796 ZINC13861043 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013414 Oc1ccc(CC(=O)N2CCCCC2CN2CCCC2)cc1 InChI=1S/C18H26N2O2/c21-17-8-6-15(7-9-17)13-18(22)20-12-2-1-5-16(20)14-19-10-3-4-11-19/h6-9,16,21H,1-5,10-14H2 ZXDHAKBZZDCMGU-UHFFFAOYSA-N 50008890 2-(4-Hydroxy-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone(HCl)::CHEMBL128912 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm00105a061 10.7270/Q23777N1 1846921 Vecchietti, V; Giordani, A; Giardina, G; Colle, R; Clarke, GD Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008890&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14810985 103921991 CHEMBL128912 ZINC13861055 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013416 Clc1ccc(CC(=O)N2CCCC[C@@H]2CN2CCCC2)cc1Cl InChI=1S/C18H24Cl2N2O/c19-16-7-6-14(11-17(16)20)12-18(23)22-10-2-1-5-15(22)13-21-8-3-4-9-21/h6-7,11,15H,1-5,8-10,12-13H2/t15-/m1/s1 GHCCBWMZKJQGLS-OAHLLOKOSA-N 50452994 CHEMBL2111857 Mu-type opioid receptor Cavia cutleri 7110 ChEMBL 10.1021/jm00105a061 10.7270/Q23777N1 1846921 Vecchietti, V; Giordani, A; Giardina, G; Colle, R; Clarke, GD Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452994&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14810948 225145802 CHEMBL2111857 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013417 FC(F)(F)c1cccc(CC(=O)N2CCCCC2CN2CCCC2)c1 InChI=1S/C19H25F3N2O/c20-19(21,22)16-7-5-6-15(12-16)13-18(25)24-11-2-1-8-17(24)14-23-9-3-4-10-23/h5-7,12,17H,1-4,8-11,13-14H2 ZVGFRYLMFAMUON-UHFFFAOYSA-N 50008898 1-(2-Pyrrolidin-1-ylmethyl-piperidin-1-yl)-2-(3-trifluoromethyl-phenyl)-ethanone(HCl)::CHEMBL128631 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm00105a061 10.7270/Q23777N1 1846921 Vecchietti, V; Giordani, A; Giardina, G; Colle, R; Clarke, GD Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008898 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008898&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14810973 103921999 CHEMBL128631 ZINC13861045 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013419 FC(F)(F)c1ccccc1CC(=O)N1CCCCC1CN1CCCC1 InChI=1S/C19H25F3N2O/c20-19(21,22)17-9-2-1-7-15(17)13-18(25)24-12-4-3-8-16(24)14-23-10-5-6-11-23/h1-2,7,9,16H,3-6,8,10-14H2 HSPFUIOJKZSLQI-UHFFFAOYSA-N 50008896 1-(2-Pyrrolidin-1-ylmethyl-piperidin-1-yl)-2-(2-trifluoromethyl-phenyl)-ethanone(HCl)::CHEMBL447782 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm00105a061 10.7270/Q23777N1 1846921 Vecchietti, V; Giordani, A; Giardina, G; Colle, R; Clarke, GD Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008896 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008896&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14810975 103921997 CHEMBL447782 ZINC13861047 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013423 O=C(Cc1ccc(cc1)C1CCCCC1)N1CCCCC1CN1CCCC1 InChI=1S/C24H36N2O/c27-24(26-17-5-4-10-23(26)19-25-15-6-7-16-25)18-20-11-13-22(14-12-20)21-8-2-1-3-9-21/h11-14,21,23H,1-10,15-19H2 QRIZARXGKJRHBY-UHFFFAOYSA-N 50008900 2-(4-Cyclohexyl-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone(HCl)::CHEMBL130714 Mu-type opioid receptor Cavia cutleri 974 ChEMBL 10.1021/jm00105a061 10.7270/Q23777N1 1846921 Vecchietti, V; Giordani, A; Giardina, G; Colle, R; Clarke, GD Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008900 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008900&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14810983 103922001 CHEMBL130714 ZINC13861053 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013424 Clc1ccc(CC(=O)N2CCCCC2CN2CCCCC2)cc1Cl InChI=1S/C19H26Cl2N2O/c20-17-8-7-15(12-18(17)21)13-19(24)23-11-5-2-6-16(23)14-22-9-3-1-4-10-22/h7-8,12,16H,1-6,9-11,13-14H2 PZKHOISBMZGAFR-UHFFFAOYSA-N 50000278 2-(3,4-Dichloro-phenyl)-1-(2-piperidin-1-ylmethyl-piperidin-1-yl)-ethanone::2-(3,4-Dichloro-phenyl)-1-(2-piperidin-1-ylmethyl-piperidin-1-yl)-ethanone(HCl)::CHEMBL131328 Mu-type opioid receptor Cavia cutleri 4810 ChEMBL 10.1021/jm00105a061 10.7270/Q23777N1 1846921 Vecchietti, V; Giordani, A; Giardina, G; Colle, R; Clarke, GD Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000278 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000278&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14810957 103914885 CHEMBL131328 ZINC13449222 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013426 CC(C1CCCCN1C(=O)Cc1ccc(Cl)c(Cl)c1)N(C)C InChI=1S/C17H24Cl2N2O/c1-12(20(2)3)16-6-4-5-9-21(16)17(22)11-13-7-8-14(18)15(19)10-13/h7-8,10,12,16H,4-6,9,11H2,1-3H3 MJVPVUAVZUCLJO-UHFFFAOYSA-N 50008889 (threo)2-(3,4-Dichloro-phenyl)-1-[2-(1-dimethylamino-ethyl)-piperidin-1-yl]-ethanone(HCl)::2-(3,4-Dichloro-phenyl)-1-[2-(1-dimethylamino-ethyl)-piperidin-1-yl]-ethanone(HCl)::CHEMBL131034 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm00105a061 10.7270/Q23777N1 1846921 Vecchietti, V; Giordani, A; Giardina, G; Colle, R; Clarke, GD Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008889 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008889&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14810989 103921990 CHEMBL131034 ZINC13884739 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013485 CCC(=O)N(c1ccccc1)C1(CCN(CCN2C(=O)c3ccccc3C2=O)CC1)C(=O)OC InChI=1S/C26H29N3O5/c1-3-22(30)29(19-9-5-4-6-10-19)26(25(33)34-2)13-15-27(16-14-26)17-18-28-23(31)20-11-7-8-12-21(20)24(28)32/h4-12H,3,13-18H2,1-2H3 WVDFBNIWZBEDNH-UHFFFAOYSA-N 50008983 1-[2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-ethyl]-4-(phenyl-propionyl-amino)-piperidine-4-carboxylic acid methyl ester::CHEMBL424400 Mu-type opioid receptor Cavia cutleri 1200 ChEMBL 10.1021/jm00106a051 10.7270/Q2TQ60H9 1847432 Bagley, JR; Thomas, SA; Rudo, FG; Spencer, HK; Doorley, BM; Ossipov, MH; Jerussi, TP; Benvenga, MJ; Spaulding, T Anaquest, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008983 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008983&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44381153 103922050 CHEMBL424400 ZINC00600548 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013488 CCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 InChI=1S/C22H28N2O/c1-2-22(25)24(20-11-7-4-8-12-20)21-14-17-23(18-15-21)16-13-19-9-5-3-6-10-19/h3-12,21H,2,13-18H2,1H3 PJMPHNIQZUBGLI-UHFFFAOYSA-N 50008984 4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-phthalazin-1-one::CHEMBL596::Duragesic-100::Duragesic-12::Duragesic-25::Duragesic-50::Duragesic-75::FENTANYL::FENTANYL CITRATE::FENTANYL-HCl::Fentanyl-100::Fentanyl-12::Fentanyl-25::Fentanyl-50::Fentanyl-75::Fentora::Innovar::Ionsys::N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide::N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide(Fentanyl)::N-(1-phenethylpiperidin-4-yl)-N-phenylpropionamide Mu-type opioid receptor Cavia cutleri 3.1 ChEMBL 10.1021/jm00106a051 10.7270/Q2TQ60H9 1847432 Bagley, JR; Thomas, SA; Rudo, FG; Spencer, HK; Doorley, BM; Ossipov, MH; Jerussi, TP; Benvenga, MJ; Spaulding, T Anaquest, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008984&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 7V7 5TZO,8EF5,7U64 3345 103922051 119915 CHEMBL596 DB00813 1626 ZINC02522669 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013489 CCC(=O)N(c1ccccc1)C1(CCN(CCn2cccn2)CC1)C(=O)OC InChI=1S/C21H28N4O3/c1-3-19(26)25(18-8-5-4-6-9-18)21(20(27)28-2)10-14-23(15-11-21)16-17-24-13-7-12-22-24/h4-9,12-13H,3,10-11,14-17H2,1-2H3 QLTFJNWRBMIGIS-UHFFFAOYSA-N 50008980 4-(Phenyl-propionyl-amino)-1-(2-pyrazol-1-yl-ethyl)-piperidine-4-carboxylic acid methyl ester::CHEMBL169366 Mu-type opioid receptor Cavia cutleri 5.4 ChEMBL 10.1021/jm00106a051 10.7270/Q2TQ60H9 1847432 Bagley, JR; Thomas, SA; Rudo, FG; Spencer, HK; Doorley, BM; Ossipov, MH; Jerussi, TP; Benvenga, MJ; Spaulding, T Anaquest, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008980 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008980&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14879862 103922047 CHEMBL169366 ZINC00597115 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013491 CCC(=O)N(c1ccccc1)C1(COC)CCN(CCn2cccn2)CC1 InChI=1S/C21H30N4O2/c1-3-20(26)25(19-8-5-4-6-9-19)21(18-27-2)10-14-23(15-11-21)16-17-24-13-7-12-22-24/h4-9,12-13H,3,10-11,14-18H2,1-2H3 DOERHXQKDUFFRK-UHFFFAOYSA-N 50008982 CHEMBL168723::N-[4-Methoxymethyl-1-(2-pyrazol-1-yl-ethyl)-piperidin-4-yl]-N-phenyl-propionamide Mu-type opioid receptor Cavia cutleri 10 ChEMBL 10.1021/jm00106a051 10.7270/Q2TQ60H9 1847432 Bagley, JR; Thomas, SA; Rudo, FG; Spencer, HK; Doorley, BM; Ossipov, MH; Jerussi, TP; Benvenga, MJ; Spaulding, T Anaquest, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008982 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008982&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14879863 103922049 CHEMBL168723 ZINC00603904 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013493 CCC(=O)N(c1ccccc1)C1(COC)CCN(CCn2nnn(CC)c2=O)CC1 InChI=1S/C21H32N6O3/c1-4-19(28)27(18-9-7-6-8-10-18)21(17-30-3)11-13-24(14-12-21)15-16-26-20(29)25(5-2)22-23-26/h6-10H,4-5,11-17H2,1-3H3 IDBPHNDTYPBSNI-UHFFFAOYSA-N 83450 ALFENTANIL::Alfentanil hydrochloride::MLS002320667::N-[1-[2-(4-ethyl-5-keto-tetrazol-1-yl)ethyl]-4-(methoxymethyl)-4-piperidyl]-N-phenyl-propionamide;hydrochloride::N-[1-[2-(4-ethyl-5-oxidanylidene-1,2,3,4-tetrazol-1-yl)ethyl]-4-(methoxymethyl)piperidin-4-yl]-N-phenyl-propanamide;hydrochloride::N-[1-[2-(4-ethyl-5-oxo-1-tetrazolyl)ethyl]-4-(methoxymethyl)-4-piperidinyl]-N-phenylpropanamide;hydrochloride::N-[1-[2-(4-ethyl-5-oxotetrazol-1-yl)ethyl]-4-(methoxymethyl)piperidin-4-yl]-N-phenylpropanamide;hydrochloride::SMR001338813::cid_64761 Mu-type opioid receptor Cavia cutleri 15 ChEMBL 10.1021/jm00106a051 10.7270/Q2TQ60H9 1847432 Bagley, JR; Thomas, SA; Rudo, FG; Spencer, HK; Doorley, BM; Ossipov, MH; Jerussi, TP; Benvenga, MJ; Spaulding, T Anaquest, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=83450 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=83450&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 51263 252658644 DB00802 C08005 ZINC05699854 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50013494 CCC(=O)N(c1ccccc1)C1(COC)CCN(CCN2C(=O)c3ccccc3C2=O)CC1 InChI=1S/C26H31N3O4/c1-3-23(30)29(20-9-5-4-6-10-20)26(19-33-2)13-15-27(16-14-26)17-18-28-24(31)21-11-7-8-12-22(21)25(28)32/h4-12H,3,13-19H2,1-2H3 XRUWVGMEGYVABH-UHFFFAOYSA-N 50008981 CHEMBL169587::N-{1-[2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-ethyl]-4-methoxymethyl-piperidin-4-yl}-N-phenyl-propionamide Mu-type opioid receptor Cavia cutleri 1600 ChEMBL 10.1021/jm00106a051 10.7270/Q2TQ60H9 1847432 Bagley, JR; Thomas, SA; Rudo, FG; Spencer, HK; Doorley, BM; Ossipov, MH; Jerussi, TP; Benvenga, MJ; Spaulding, T Anaquest, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008981 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008981&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380786 103922048 CHEMBL169587 ZINC27988002 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010303 CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23-,24-/m0/s1 MCMMCRYPQBNCPH-DVKRWUGUSA-N 50001683 13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid::7-Benzyl-10-{[3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL294616::DPDPE Mu-type opioid receptor Cavia cutleri 577 ChEMBL 10.1016/s0960-894x(99)00525-9 10.7270/Q28916BJ 10571174 Thomas, JB; Herault, XM; Rothman, RB; Burgess, JP; Mascarella, SW; Xu, H; Horel, RB; Dersch, CM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001683&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299404 103916113 CHEMBL294616 ZINC27520031 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010307 CCN(CC)C(=O)c1ccc(cc1)[C@@H](N1C[C@@H](C)N(CC=C)C[C@@H]1C)c1cccc(OC)c1 InChI=1S/C28H39N3O2/c1-7-17-30-19-22(5)31(20-21(30)4)27(25-11-10-12-26(18-25)33-6)23-13-15-24(16-14-23)28(32)29(8-2)9-3/h7,10-16,18,21-22,27H,1,8-9,17,19-20H2,2-6H3/t21-,22+,27-/m1/s1 KQWVAUSXZDRQPZ-UMTXDNHDSA-N 50039029 (+)-4-((alpha R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-methoxyphenyl)methyl)-N,N-diethylbenzamide::(+)-4-[(alpha-R)-alpha-[2S,5R]-4-allyl[2,5-dimethyl-1-piperazinyl]-3-methoxybenzyl]-N,N-diethylbenzamide::3-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(4-diethylcarbamoyl-phenyl)-methyl]-benzoic acid::4-((R)-((2R,5S)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-methoxyphenyl)methyl)-N,N-diethylbenzamide::4-((R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-methoxyphenyl)methyl)-N,N-diethylbenzamide::4-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide (SNC 80)::4-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide(SNC-80)::4-[(R)-((2R,5S)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-((R)-4-(S)-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-[(2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl](3-methoxyphenyl)-methyl]-N,N-diethylbenzamide::CHEMBL13470::SNC-80 Mu-type opioid receptor Cavia cutleri 673 ChEMBL 10.1016/s0960-894x(99)00525-9 10.7270/Q28916BJ 10571174 Thomas, JB; Herault, XM; Rothman, RB; Burgess, JP; Mascarella, SW; Xu, H; Horel, RB; Dersch, CM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039029&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 123924 103946292 CHEMBL13470 1611 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010312 CCN(CC)C(=O)c1ccc(cc1)N([C@H]1CCN(CC=C)CC1C)c1ccccc1 InChI=1S/C26H35N3O/c1-5-18-27-19-17-25(21(4)20-27)29(23-11-9-8-10-12-23)24-15-13-22(14-16-24)26(30)28(6-2)7-3/h5,8-16,21,25H,1,6-7,17-20H2,2-4H3/t21?,25-/m0/s1 DZIVFTSZIVQCKX-QBGQUKIHSA-N 50082339 4-[((S)-1-Allyl-3-methyl-piperidin-4-yl)-phenyl-amino]-N,N-diethyl-benzamide::CHEMBL430475 Mu-type opioid receptor Cavia cutleri 4667 ChEMBL 10.1016/s0960-894x(99)00525-9 10.7270/Q28916BJ 10571174 Thomas, JB; Herault, XM; Rothman, RB; Burgess, JP; Mascarella, SW; Xu, H; Horel, RB; Dersch, CM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082339 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082339&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44334383 103982142 CHEMBL430475 ZINC13862297 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010314 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C)[C@@H](Cc1ccccc1)C(=O)NCCO InChI=1S/C26H35N5O6/c1-17(30-25(36)21(27)14-19-8-10-20(33)11-9-19)24(35)29-16-23(34)31(2)22(26(37)28-12-13-32)15-18-6-4-3-5-7-18/h3-11,17,21-22,32-33H,12-16,27H2,1-2H3,(H,28,37)(H,29,35)(H,30,36)/t17-,21+,22+/m1/s1 HPZJMUBDEAMBFI-WTNAPCKOSA-N 21015 (2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]-N-methylacetamido}-N-(2-hydroxyethyl)-3-phenylpropanamide::2-Ala-4-MePhe-5-Gly-Enkephalin::CHEMBL38874::D-Ala2-MePhe4-Met(0)5-enkephalin-ol::DAMGO::RX 783006::US11492374, ID 2::[3H]DAMGO::[tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephalin Mu-type opioid receptor Cavia cutleri 592 ChEMBL 10.1016/s0960-894x(99)00525-9 10.7270/Q28916BJ 10571174 Thomas, JB; Herault, XM; Rothman, RB; Burgess, JP; Mascarella, SW; Xu, H; Horel, RB; Dersch, CM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21015&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5462471 49689088 CHEMBL38874 1647 C04080 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50012718 C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)N1CCCCC1 InChI=1S/C23H34N2/c1-17-22-14-19-8-9-20(24-11-4-3-5-12-24)15-21(19)23(17,2)10-13-25(22)16-18-6-7-18/h8-9,15,17-18,22H,3-7,10-14,16H2,1-2H3/t17-,22?,23-/m0/s1 DINHVBGJVOAMBL-XHLMSTEBSA-N 50085032 (6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-8-piperidin-1-yl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine; dihydrochloride::CHEMBL168625::CHEMBL543563 Mu-type opioid receptor Cavia cutleri 950 ChEMBL 10.1016/s0960-894x(99)00670-8 10.7270/Q2571CH7 10673107 Wentland, MP; Xu, G; Cioffi, CL; Ye, Y; Duan, W; Cohen, DJ; Colasurdo, AM; Bidlack, JM Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085032&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44298213 103984515 CHEMBL543563CHEMBL168625 ZINC27901463 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50012719 C[C@H]1C2Cc3ccc(NCc4ccccc4)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C25H32N2/c1-18-24-14-21-10-11-22(26-16-19-6-4-3-5-7-19)15-23(21)25(18,2)12-13-27(24)17-20-8-9-20/h3-7,10-11,15,18,20,24,26H,8-9,12-14,16-17H2,1-2H3/t18-,24?,25-/m0/s1 BZXKIAFEGKPVMG-VNYPPZAHSA-N 50085021 Benzyl-((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-amine::Benzyl-(3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-amine::Benzyl-(3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-amine.2HCl::CHEMBL301835 Mu-type opioid receptor Cavia cutleri 1.50 ChEMBL 10.1016/s0960-894x(99)00670-8 10.7270/Q2571CH7 10673107 Wentland, MP; Xu, G; Cioffi, CL; Ye, Y; Duan, W; Cohen, DJ; Colasurdo, AM; Bidlack, JM Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085021&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10473705 103984504 CHEMBL301835 ZINC13493431 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010507 CCN(CC)C(=O)c1ccc(cc1)[C@@H](N1C[C@@H](C)N(CC=C)C[C@@H]1C)c1cccc(OC)c1 InChI=1S/C28H39N3O2/c1-7-17-30-19-22(5)31(20-21(30)4)27(25-11-10-12-26(18-25)33-6)23-13-15-24(16-14-23)28(32)29(8-2)9-3/h7,10-16,18,21-22,27H,1,8-9,17,19-20H2,2-6H3/t21-,22+,27-/m1/s1 KQWVAUSXZDRQPZ-UMTXDNHDSA-N 50039029 (+)-4-((alpha R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-methoxyphenyl)methyl)-N,N-diethylbenzamide::(+)-4-[(alpha-R)-alpha-[2S,5R]-4-allyl[2,5-dimethyl-1-piperazinyl]-3-methoxybenzyl]-N,N-diethylbenzamide::3-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(4-diethylcarbamoyl-phenyl)-methyl]-benzoic acid::4-((R)-((2R,5S)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-methoxyphenyl)methyl)-N,N-diethylbenzamide::4-((R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-methoxyphenyl)methyl)-N,N-diethylbenzamide::4-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide (SNC 80)::4-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide(SNC-80)::4-[(R)-((2R,5S)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-((R)-4-(S)-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-[(2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl](3-methoxyphenyl)-methyl]-N,N-diethylbenzamide::CHEMBL13470::SNC-80 Mu-type opioid receptor Cavia cutleri 317 ChEMBL 10.1016/s0960-894x(99)00613-7 10.7270/Q2MK6DDP 10612597 Thomas, JB; Atkinson, RN; Herault, XM; Rothman, RB; Mascarella, SW; Dersch, CM; Xu, H; Horel, RB; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039029&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 123924 103946292 CHEMBL13470 1611 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010508 CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CC=C)CC1C)c1ccccc1 InChI=1S/C26H35N3O/c1-5-18-27-19-17-25(21(4)20-27)29(23-11-9-8-10-12-23)24-15-13-22(14-16-24)26(30)28(6-2)7-3/h5,8-16,21,25H,1,6-7,17-20H2,2-4H3 DZIVFTSZIVQCKX-UHFFFAOYSA-N 50083636 4-[(1-Allyl-3-methyl-piperidin-4-yl)-phenyl-amino]-N,N-diethyl-benzamide::CHEMBL115730 Mu-type opioid receptor Cavia cutleri 3500 ChEMBL 10.1016/s0960-894x(99)00613-7 10.7270/Q2MK6DDP 10612597 Thomas, JB; Atkinson, RN; Herault, XM; Rothman, RB; Mascarella, SW; Dersch, CM; Xu, H; Horel, RB; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083636&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 22475272 103983282 CHEMBL115730 ZINC13862297 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010509 CCN(CC)C(=O)c1ccc(cc1)N([C@H]1CCN(CC=C)C[C@H]1C)c1ccccc1 InChI=1S/C26H35N3O/c1-5-18-27-19-17-25(21(4)20-27)29(23-11-9-8-10-12-23)24-15-13-22(14-16-24)26(30)28(6-2)7-3/h5,8-16,21,25H,1,6-7,17-20H2,2-4H3/t21-,25+/m1/s1 DZIVFTSZIVQCKX-BWKNWUBXSA-N 50082341 4-[((3R,4S)-1-Allyl-3-methyl-piperidin-4-yl)-phenyl-amino]-N,N-diethyl-benzamide::CHEMBL102497 Mu-type opioid receptor Cavia cutleri 3604 ChEMBL 10.1016/s0960-894x(99)00613-7 10.7270/Q2MK6DDP 10612597 Thomas, JB; Atkinson, RN; Herault, XM; Rothman, RB; Mascarella, SW; Dersch, CM; Xu, H; Horel, RB; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082341&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9887566 103982144 CHEMBL102497 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010513 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C)[C@@H](Cc1ccccc1)C(=O)NCCO InChI=1S/C26H35N5O6/c1-17(30-25(36)21(27)14-19-8-10-20(33)11-9-19)24(35)29-16-23(34)31(2)22(26(37)28-12-13-32)15-18-6-4-3-5-7-18/h3-11,17,21-22,32-33H,12-16,27H2,1-2H3,(H,28,37)(H,29,35)(H,30,36)/t17-,21+,22+/m1/s1 HPZJMUBDEAMBFI-WTNAPCKOSA-N 21015 (2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]-N-methylacetamido}-N-(2-hydroxyethyl)-3-phenylpropanamide::2-Ala-4-MePhe-5-Gly-Enkephalin::CHEMBL38874::D-Ala2-MePhe4-Met(0)5-enkephalin-ol::DAMGO::RX 783006::US11492374, ID 2::[3H]DAMGO::[tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephalin Mu-type opioid receptor Cavia cutleri 592 ChEMBL 10.1016/s0960-894x(99)00613-7 10.7270/Q2MK6DDP 10612597 Thomas, JB; Atkinson, RN; Herault, XM; Rothman, RB; Mascarella, SW; Dersch, CM; Xu, H; Horel, RB; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21015&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5462471 49689088 CHEMBL38874 1647 C04080 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010533 CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23-,24-/m0/s1 MCMMCRYPQBNCPH-DVKRWUGUSA-N 50001683 13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid::7-Benzyl-10-{[3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL294616::DPDPE Mu-type opioid receptor Cavia cutleri 577 ChEMBL 10.1016/s0960-894x(99)00613-7 10.7270/Q2MK6DDP 10612597 Thomas, JB; Atkinson, RN; Herault, XM; Rothman, RB; Mascarella, SW; Dersch, CM; Xu, H; Horel, RB; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001683&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299404 103916113 CHEMBL294616 ZINC27520031 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50016069 Oc1ccc2CC3N(CC4CC4)CCC45[C@@H](Oc1c24)c1c(C[C@@]35NC=O)c2ccccc2n1CCCF InChI=1S/C30H32FN3O3/c31-11-3-12-34-22-5-2-1-4-20(22)21-15-30(32-17-35)24-14-19-8-9-23(36)27-25(19)29(30,28(37-27)26(21)34)10-13-33(24)16-18-6-7-18/h1-2,4-5,8-9,17-18,24,28,36H,3,6-7,10-16H2,(H,32,35)/t24?,28-,29?,30+/m0/s1 OGZRDZOVPFECSZ-FKKYHJNPSA-N 50098198 CHEMBL170399::N-[22-cyclopropylmethyl-11-(3-fluoropropyl)-16-hydroxy-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaen-2-yl]methanamide Mu-type opioid receptor Cavia cutleri 21 ChEMBL 10.1016/s0960-894x(01)00112-3 10.7270/Q21V5FG3 11294396 Clayson, J; Jales, A; Tyacke, RJ; Hudson, AL; Nutt, DJ; Lewis, JW; Husbands, SM University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098198 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098198&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44383911 103995289 CHEMBL170399 C06049 ZINC28006824 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50016072 CCCN[C@]12Cc3c([nH]c4ccccc34)[C@@H]3Oc4c5c(CC1N(CC1CC1)CCC235)ccc4OC InChI=1S/C30H35N3O2/c1-3-13-31-30-16-21-20-6-4-5-7-22(20)32-26(21)28-29(30)12-14-33(17-18-8-9-18)24(30)15-19-10-11-23(34-2)27(35-28)25(19)29/h4-7,10-11,18,24,28,31-32H,3,8-9,12-17H2,1-2H3/t24?,28-,29?,30+/m0/s1 BSBAARDUXYFUGY-FKKYHJNPSA-N 50098197 2N-propyl-22-cyclopropylmethyl-16-methoxy-(13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaen-2-amine::CHEMBL367290 Mu-type opioid receptor Cavia cutleri 5191 ChEMBL 10.1016/s0960-894x(01)00112-3 10.7270/Q21V5FG3 11294396 Clayson, J; Jales, A; Tyacke, RJ; Hudson, AL; Nutt, DJ; Lewis, JW; Husbands, SM University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098197 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098197&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44384062 103995288 CHEMBL367290 ZINC36221404 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50016079 Oc1ccc2CC3N(CC4CC4)CCC45[C@@H](Oc1c24)c1c(C[C@@]35NC=O)c2ccccc2n1CCF InChI=1S/C29H30FN3O3/c30-10-12-33-21-4-2-1-3-19(21)20-14-29(31-16-34)23-13-18-7-8-22(35)26-24(18)28(29,27(36-26)25(20)33)9-11-32(23)15-17-5-6-17/h1-4,7-8,16-17,23,27,35H,5-6,9-15H2,(H,31,34)/t23?,27-,28?,29+/m0/s1 FVJKGTJAWSOAJN-SXNYVGIYSA-N 50098201 CHEMBL367962::N-[22-cyclopropylmethyl-11-(2-fluoroethyl)-16-hydroxy-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaen-2-yl]methanamide Mu-type opioid receptor Cavia cutleri 32 ChEMBL 10.1016/s0960-894x(01)00112-3 10.7270/Q21V5FG3 11294396 Clayson, J; Jales, A; Tyacke, RJ; Hudson, AL; Nutt, DJ; Lewis, JW; Husbands, SM University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098201 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098201&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44384018 103995292 CHEMBL367962 C06049 ZINC28008005 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50016080 CN1CCC23[C@H]4Oc5c2c(CC1[C@]3(O)Cc1c4n(CCCF)c2ccccc12)ccc5O InChI=1S/C26H27FN2O3/c1-28-12-9-25-21-15-7-8-19(30)23(21)32-24(25)22-17(14-26(25,31)20(28)13-15)16-5-2-3-6-18(16)29(22)11-4-10-27/h2-3,5-8,20,24,30-31H,4,9-14H2,1H3/t20?,24-,25?,26+/m0/s1 PXKNNIADRAABBC-RFTKNZGOSA-N 50098202 11-(3-fluoropropyl)-22-methyl-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol::CHEMBL173749 Mu-type opioid receptor Cavia cutleri 71 ChEMBL 10.1016/s0960-894x(01)00112-3 10.7270/Q21V5FG3 11294396 Clayson, J; Jales, A; Tyacke, RJ; Hudson, AL; Nutt, DJ; Lewis, JW; Husbands, SM University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098202 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098202&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44383845 103995293 CHEMBL173749 ZINC36221394 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50016086 COc1ccc2CC3N(CC4CC4)CCC45[C@@H](Oc1c24)c1[nH]c2ccccc2c1C[C@@]35NCCCF InChI=1S/C30H34FN3O2/c1-35-23-10-9-19-15-24-30(32-13-4-12-31)16-21-20-5-2-3-6-22(20)33-26(21)28-29(30,25(19)27(23)36-28)11-14-34(24)17-18-7-8-18/h2-3,5-6,9-10,18,24,28,32-33H,4,7-8,11-17H2,1H3/t24?,28-,29?,30+/m0/s1 WSLMJRMDWOYIDB-FKKYHJNPSA-N 50098191 2N-(3-fluoropropyl)-22-cyclopropylmethyl-16-methoxy-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaen-2-amine::CHEMBL173319 Mu-type opioid receptor Cavia cutleri 5127 ChEMBL 10.1016/s0960-894x(01)00112-3 10.7270/Q21V5FG3 11294396 Clayson, J; Jales, A; Tyacke, RJ; Hudson, AL; Nutt, DJ; Lewis, JW; Husbands, SM University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098191&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44383840 103995282 CHEMBL173319 ZINC36221401 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50016090 Cn1c2[C@@H]3Oc4c5c(C[C@H]6N(CC7CC7)CC[C@@]35[C@@]6(O)Cc2c2ccccc12)ccc4O InChI=1S/C27H28N2O3/c1-28-19-5-3-2-4-17(19)18-13-27(31)21-12-16-8-9-20(30)24-22(16)26(27,25(32-24)23(18)28)10-11-29(21)14-15-6-7-15/h2-5,8-9,15,21,25,30-31H,6-7,10-14H2,1H3/t21-,25+,26+,27-/m1/s1 CRTCCMARDBQOKA-NVSKSXHLSA-N 50451343 CHEMBL477154 Mu-type opioid receptor Cavia cutleri 39 ChEMBL 10.1016/s0960-894x(01)00112-3 10.7270/Q21V5FG3 11294396 Clayson, J; Jales, A; Tyacke, RJ; Hudson, AL; Nutt, DJ; Lewis, JW; Husbands, SM University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50451343 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50451343&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5362396 225145344 CHEMBL477154 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50016091 Oc1ccc2CC3N(CC4CC4)CCC45[C@@H](Oc1c24)c1c(C[C@@]35O)c2ccccc2n1CCF InChI=1S/C28H29FN2O3/c29-10-12-31-20-4-2-1-3-18(20)19-14-28(33)22-13-17-7-8-21(32)25-23(17)27(28,26(34-25)24(19)31)9-11-30(22)15-16-5-6-16/h1-4,7-8,16,22,26,32-33H,5-6,9-15H2/t22?,26-,27?,28+/m0/s1 BNEYLUYLEILILO-AMLGIXIYSA-N 50098195 22-cyclopropylmethyl-11-(2-fluoroethyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol::CHEMBL368522 Mu-type opioid receptor Cavia cutleri 17 ChEMBL 10.1016/s0960-894x(01)00112-3 10.7270/Q21V5FG3 11294396 Clayson, J; Jales, A; Tyacke, RJ; Hudson, AL; Nutt, DJ; Lewis, JW; Husbands, SM University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098195&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44385170 103995286 CHEMBL368522 ZINC28087269 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50016095 CN1CCC23[C@H]4Oc5c2c(CC1[C@]3(O)Cc1c4n(CCF)c2ccccc12)ccc5O InChI=1S/C25H25FN2O3/c1-27-10-8-24-20-14-6-7-18(29)22(20)31-23(24)21-16(13-25(24,30)19(27)12-14)15-4-2-3-5-17(15)28(21)11-9-26/h2-7,19,23,29-30H,8-13H2,1H3/t19?,23-,24?,25+/m0/s1 DQJXRRAONCGJHB-RDGOQYLZSA-N 50098194 11-(2-fluoroethyl)-22-methyl-(2S)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol::CHEMBL435898 Mu-type opioid receptor Cavia cutleri 30 ChEMBL 10.1016/s0960-894x(01)00112-3 10.7270/Q21V5FG3 11294396 Clayson, J; Jales, A; Tyacke, RJ; Hudson, AL; Nutt, DJ; Lewis, JW; Husbands, SM University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098194 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098194&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44385172 103995285 CHEMBL435898 ZINC36221411 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50016099 CCN[C@]12Cc3c([nH]c4ccccc34)[C@@H]3Oc4c5c(CC1N(CC1CC1)CCC235)ccc4O InChI=1S/C28H31N3O2/c1-2-29-28-14-19-18-5-3-4-6-20(18)30-24(19)26-27(28)11-12-31(15-16-7-8-16)22(28)13-17-9-10-21(32)25(33-26)23(17)27/h3-6,9-10,16,22,26,29-30,32H,2,7-8,11-15H2,1H3/t22?,26-,27?,28+/m0/s1 KQAUZBBJUMKUBZ-AMLGIXIYSA-N 50098186 22-cyclopropylmethyl-2-ethylamino-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaen-16-ol::CHEMBL173874 Mu-type opioid receptor Cavia cutleri 90 ChEMBL 10.1016/s0960-894x(01)00112-3 10.7270/Q21V5FG3 11294396 Clayson, J; Jales, A; Tyacke, RJ; Hudson, AL; Nutt, DJ; Lewis, JW; Husbands, SM University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098186 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098186&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44383903 103995277 CHEMBL173874 ZINC36221396 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50016101 COc1ccc2CC3N(CC4CC4)CCC45[C@@H](Oc1c24)c1[nH]c2ccccc2c1C[C@@]35N InChI=1S/C27H29N3O2/c1-31-20-9-8-16-12-21-27(28)13-18-17-4-2-3-5-19(17)29-23(18)25-26(27,22(16)24(20)32-25)10-11-30(21)14-15-6-7-15/h2-5,8-9,15,21,25,29H,6-7,10-14,28H2,1H3/t21?,25-,26?,27+/m0/s1 FMWAPMNLTHJZRN-NNMXSAHVSA-N 50098190 22-cyclopropylmethyl-16-methoxy-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaen-2-amine::CHEMBL177194 Mu-type opioid receptor Cavia cutleri 14700 ChEMBL 10.1016/s0960-894x(01)00112-3 10.7270/Q21V5FG3 11294396 Clayson, J; Jales, A; Tyacke, RJ; Hudson, AL; Nutt, DJ; Lewis, JW; Husbands, SM University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098190&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44385119 103995281 CHEMBL177194 ZINC36221413 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50016102 Oc1ccc2CC3N(CC4CC4)CCC45[C@@H](Oc1c24)c1c(C[C@@]35O)c2ccccc2n1CCCF InChI=1S/C29H31FN2O3/c30-11-3-12-32-21-5-2-1-4-19(21)20-15-29(34)23-14-18-8-9-22(33)26-24(18)28(29,27(35-26)25(20)32)10-13-31(23)16-17-6-7-17/h1-2,4-5,8-9,17,23,27,33-34H,3,6-7,10-16H2/t23?,27-,28?,29+/m0/s1 YVTDFKWJICCMTQ-SXNYVGIYSA-N 50098196 22-cyclopropylmethyl-11-(3-fluoropropyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol::CHEMBL368421 Mu-type opioid receptor Cavia cutleri 19 ChEMBL 10.1016/s0960-894x(01)00112-3 10.7270/Q21V5FG3 11294396 Clayson, J; Jales, A; Tyacke, RJ; Hudson, AL; Nutt, DJ; Lewis, JW; Husbands, SM University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098196 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098196&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44385238 103995287 CHEMBL368421 ZINC28013803 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50016104 CCCn1c2[C@@H]3Oc4c5c(CC6N(CC7CC7)CCC35[C@@]6(O)Cc2c2ccccc12)ccc4O InChI=1S/C29H32N2O3/c1-2-12-31-21-6-4-3-5-19(21)20-15-29(33)23-14-18-9-10-22(32)26-24(18)28(29,27(34-26)25(20)31)11-13-30(23)16-17-7-8-17/h3-6,9-10,17,23,27,32-33H,2,7-8,11-16H2,1H3/t23?,27-,28?,29+/m0/s1 BAAJOVWJVHHJDR-SXNYVGIYSA-N 50098199 22-cyclopropylmethyl-11-propyl-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol::CHEMBL172493 Mu-type opioid receptor Cavia cutleri 16 ChEMBL 10.1016/s0960-894x(01)00112-3 10.7270/Q21V5FG3 11294396 Clayson, J; Jales, A; Tyacke, RJ; Hudson, AL; Nutt, DJ; Lewis, JW; Husbands, SM University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098199 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098199&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44385239 103995290 CHEMBL172493 ZINC28013818 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50016109 COc1ccc2CC3N(CC4CC4)CCC45[C@@H](Oc1c24)c1[nH]c2ccccc2c1C[C@@]35NCCF InChI=1S/C29H32FN3O2/c1-34-22-9-8-18-14-23-29(31-12-11-30)15-20-19-4-2-3-5-21(19)32-25(20)27-28(29,24(18)26(22)35-27)10-13-33(23)16-17-6-7-17/h2-5,8-9,17,23,27,31-32H,6-7,10-16H2,1H3/t23?,27-,28?,29+/m0/s1 HJNCNAIGIZQYNY-SXNYVGIYSA-N 50098200 2N-(2-fluoroethyl)-22-cyclopropylmethyl-16-methoxy-(13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaen-2-amine::CHEMBL353930 Mu-type opioid receptor Cavia cutleri 214 ChEMBL 10.1016/s0960-894x(01)00112-3 10.7270/Q21V5FG3 11294396 Clayson, J; Jales, A; Tyacke, RJ; Hudson, AL; Nutt, DJ; Lewis, JW; Husbands, SM University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098200 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098200&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44383702 103995291 CHEMBL353930 ZINC36221392 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50016113 CCCSCCCN[C@]12Cc3c([nH]c4ccccc34)[C@@H]3Oc4c5c(CC1N(CC1CC1)CCC235)ccc4O InChI=1S/C32H39N3O2S/c1-2-15-38-16-5-13-33-32-18-23-22-6-3-4-7-24(22)34-28(23)30-31(32)12-14-35(19-20-8-9-20)26(32)17-21-10-11-25(36)29(37-30)27(21)31/h3-4,6-7,10-11,20,26,30,33-34,36H,2,5,8-9,12-19H2,1H3/t26?,30-,31?,32+/m0/s1 DQVXWTOGGHLRKE-BWECXMPQSA-N 50098187 22-cyclopropylmethyl-2-(3-propylsulfanylpropylamino)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaen-16-ol::CHEMBL172529 Mu-type opioid receptor Cavia cutleri 8.1 ChEMBL 10.1016/s0960-894x(01)00112-3 10.7270/Q21V5FG3 11294396 Clayson, J; Jales, A; Tyacke, RJ; Hudson, AL; Nutt, DJ; Lewis, JW; Husbands, SM University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098187 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098187&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44384534 103995278 CHEMBL172529 ZINC36221409 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50016116 CCn1c2[C@@H]3Oc4c5c(CC6N(CC7CC7)CCC35[C@@]6(O)Cc2c2ccccc12)ccc4O InChI=1S/C28H30N2O3/c1-2-30-20-6-4-3-5-18(20)19-14-28(32)22-13-17-9-10-21(31)25-23(17)27(28,26(33-25)24(19)30)11-12-29(22)15-16-7-8-16/h3-6,9-10,16,22,26,31-32H,2,7-8,11-15H2,1H3/t22?,26-,27?,28+/m0/s1 CMWRRNPRWLSKFN-AMLGIXIYSA-N 50098192 22-cyclopropylmethyl-11-ethyl-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol::CHEMBL367497 Mu-type opioid receptor Cavia cutleri 22 ChEMBL 10.1016/s0960-894x(01)00112-3 10.7270/Q21V5FG3 11294396 Clayson, J; Jales, A; Tyacke, RJ; Hudson, AL; Nutt, DJ; Lewis, JW; Husbands, SM University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098192 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098192&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44385245 103995283 CHEMBL367497 ZINC28018920 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50016120 CCN[C@]12Cc3c([nH]c4ccccc34)[C@@H]3Oc4c5c(CC1N(CC1CC1)CCC235)ccc4OC InChI=1S/C29H33N3O2/c1-3-30-29-15-20-19-6-4-5-7-21(19)31-25(20)27-28(29)12-13-32(16-17-8-9-17)23(29)14-18-10-11-22(33-2)26(34-27)24(18)28/h4-7,10-11,17,23,27,30-31H,3,8-9,12-16H2,1-2H3/t23?,27-,28?,29+/m0/s1 RPOLGBPKNUMVDY-SXNYVGIYSA-N 50098185 2N-ethyl-22-cyclopropylmethyl-16-methoxy-(13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaen-2-amine::CHEMBL174263 Mu-type opioid receptor Cavia cutleri 671 ChEMBL 10.1016/s0960-894x(01)00112-3 10.7270/Q21V5FG3 11294396 Clayson, J; Jales, A; Tyacke, RJ; Hudson, AL; Nutt, DJ; Lewis, JW; Husbands, SM University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098185 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098185&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44383956 103995276 CHEMBL174263 ZINC36221399 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50016121 CCCN[C@]12Cc3c([nH]c4ccccc34)[C@@H]3Oc4c5c(CC1N(CC1CC1)CCC235)ccc4O InChI=1S/C29H33N3O2/c1-2-12-30-29-15-20-19-5-3-4-6-21(19)31-25(20)27-28(29)11-13-32(16-17-7-8-17)23(29)14-18-9-10-22(33)26(34-27)24(18)28/h3-6,9-10,17,23,27,30-31,33H,2,7-8,11-16H2,1H3/t23?,27-,28?,29+/m0/s1 SOLYWHPCUILIER-SXNYVGIYSA-N 50098193 22-cyclopropylmethyl-2-propylamino-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaen-16-ol::CHEMBL368600 Mu-type opioid receptor Cavia cutleri 125 ChEMBL 10.1016/s0960-894x(01)00112-3 10.7270/Q21V5FG3 11294396 Clayson, J; Jales, A; Tyacke, RJ; Hudson, AL; Nutt, DJ; Lewis, JW; Husbands, SM University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098193 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098193&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44383955 103995284 CHEMBL368600 ZINC36221406 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50016122 Oc1ccc2C[C@H]3N(CC4CC4)CCC45C(Oc1c24)c1[nH]c2ccccc2c1CC35O InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1 WIYUZYBFCWCCQJ-XEWUMVRVSA-N 21864 (21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.0^{1,13}.0^{2,21}.0^{4,12}.0^{5,10}.0^{19,25}]pentacosa-4(12),5,7,9,15,17,19(25)-heptaene-2,16-diol::(8R)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol::NALTRINDOLE::[3H]-naltrindole Mu-type opioid receptor Cavia cutleri 28 ChEMBL 10.1016/s0960-894x(01)00112-3 10.7270/Q21V5FG3 11294396 Clayson, J; Jales, A; Tyacke, RJ; Hudson, AL; Nutt, DJ; Lewis, JW; Husbands, SM University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21864&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3034754 49700969 ZINC62153992 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50016123 Oc1ccc2CC3N(CC4CC4)CCC45[C@@H](Oc1c24)c1[nH]c2ccccc2c1C[C@@]35NC=O InChI=1S/C27H27N3O3/c31-14-28-27-12-18-17-3-1-2-4-19(17)29-23(18)25-26(27)9-10-30(13-15-5-6-15)21(27)11-16-7-8-20(32)24(33-25)22(16)26/h1-4,7-8,14-15,21,25,29,32H,5-6,9-13H2,(H,28,31)/t21?,25-,26?,27+/m0/s1 OAJBJXKXMDIMEQ-NNMXSAHVSA-N 50098188 CHEMBL176537::N-[22-cyclopropylmethyl-16-hydroxy-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaen-2-yl]methanamide Mu-type opioid receptor Cavia cutleri 36 ChEMBL 10.1016/s0960-894x(01)00112-3 10.7270/Q21V5FG3 11294396 Clayson, J; Jales, A; Tyacke, RJ; Hudson, AL; Nutt, DJ; Lewis, JW; Husbands, SM University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098188 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098188&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44385163 103995279 CHEMBL176537 C06049 ZINC28019382 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015268 Oc1ccc2c(C[C@@H]3[C@@H]4CCCCC24CCN3CCCC#N)c1 InChI=1S/C20H26N2O/c21-10-3-4-11-22-12-9-20-8-2-1-5-18(20)19(22)14-15-13-16(23)6-7-17(15)20/h6-7,13,18-19,23H,1-5,8-9,11-12,14H2/t18-,19+,20?/m0/s1 RYUUGRRMHLGIOS-ABZYKWASSA-N 50105479 3-[5-hydroxy-(1R,9R,10R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-17-yl]propyl cyanide::CHEMBL327935 Mu-type opioid receptor Cavia cutleri 0.160000 ChEMBL 10.1016/s0960-894x(01)00543-1 10.7270/Q25T3M01 11591513 Neumeyer, JL; Gu, XH; van Vliet, LA; DeNunzio, NJ; Rusovici, DE; Cohen, DJ; Negus, SS; Mello, NK; Bidlack, JM Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105479&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325483 104001196 CHEMBL327935 ZINC26656098 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015269 Oc1ccc2c(C[C@@H]3[C@@H]4CCCCC24CCN3CCC#N)c1 InChI=1S/C19H24N2O/c20-9-3-10-21-11-8-19-7-2-1-4-17(19)18(21)13-14-12-15(22)5-6-16(14)19/h5-6,12,17-18,22H,1-4,7-8,10-11,13H2/t17-,18+,19?/m0/s1 YRWTXLOIJMVJMG-PAMZHZACSA-N 50105497 2-[5-hydroxy-(1R,9R,10R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-17-yl]ethyl cyanide::CHEMBL93731 Mu-type opioid receptor Cavia cutleri 0.330000 ChEMBL 10.1016/s0960-894x(01)00543-1 10.7270/Q25T3M01 11591513 Neumeyer, JL; Gu, XH; van Vliet, LA; DeNunzio, NJ; Rusovici, DE; Cohen, DJ; Negus, SS; Mello, NK; Bidlack, JM Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105497 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105497&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325484 104001214 CHEMBL93731 ZINC26653298 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015273 CC[C@]12CCN(CC3CC3)C([C@@H]1C)C(=O)c1ccc(O)cc21 InChI=1S/C19H25NO2/c1-3-19-8-9-20(11-13-4-5-13)17(12(19)2)18(22)15-7-6-14(21)10-16(15)19/h6-7,10,12-13,17,21H,3-5,8-9,11H2,1-2H3/t12-,17?,19-/m0/s1 SEJUQQOPVAUETF-BKBNBNODSA-N 50000091 (6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::(6S,11R)-3-Cyclopropylmethyl-9-hydroxy-6,11-dimethyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one (ethylketocyclazocine)::3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one(Ethylketazocine, EKC)::CHEMBL279968::EKC::EKC(-) Mu-type opioid receptor Cavia cutleri 0.780000 ChEMBL 10.1016/s0960-894x(01)00543-1 10.7270/Q25T3M01 11591513 Neumeyer, JL; Gu, XH; van Vliet, LA; DeNunzio, NJ; Rusovici, DE; Cohen, DJ; Negus, SS; Mello, NK; Bidlack, JM Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000091&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44273397 103914788 CHEMBL279968 ZINC00967957 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015279 OC(CCN1CCC23CCCC[C@H]2[C@H]1Cc1cc(O)ccc31)c1ccccc1 InChI=1S/C25H31NO2/c27-20-9-10-21-19(16-20)17-23-22-8-4-5-12-25(21,22)13-15-26(23)14-11-24(28)18-6-2-1-3-7-18/h1-3,6-7,9-10,16,22-24,27-28H,4-5,8,11-15,17H2/t22-,23+,24?,25?/m0/s1 MLRMWYVTBABRJB-IQCRSTAESA-N 50105476 17-(3-hydroxy-3-phenylpropyl)-(1R,9R,10R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-5-ol::CHEMBL92349::MCL-121 Mu-type opioid receptor Cavia cutleri 21 ChEMBL 10.1016/s0960-894x(01)00543-1 10.7270/Q25T3M01 11591513 Neumeyer, JL; Gu, XH; van Vliet, LA; DeNunzio, NJ; Rusovici, DE; Cohen, DJ; Negus, SS; Mello, NK; Bidlack, JM Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105476 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105476&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325318 104001193 CHEMBL92349 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015280 Oc1ccc2c(C[C@@H]3[C@@H]4CCCCC24CCN3Cc2ccccc2)c1 InChI=1S/C23H27NO/c25-19-9-10-20-18(14-19)15-22-21-8-4-5-11-23(20,21)12-13-24(22)16-17-6-2-1-3-7-17/h1-3,6-7,9-10,14,21-22,25H,4-5,8,11-13,15-16H2/t21-,22+,23?/m0/s1 OBRMIIBKUGYRAY-ZVTBYLAHSA-N 50105488 17-benzyl-(1R,9R,10R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-5-ol::CHEMBL96785::MCL-111 Mu-type opioid receptor Cavia cutleri 20 ChEMBL 10.1016/s0960-894x(01)00543-1 10.7270/Q25T3M01 11591513 Neumeyer, JL; Gu, XH; van Vliet, LA; DeNunzio, NJ; Rusovici, DE; Cohen, DJ; Negus, SS; Mello, NK; Bidlack, JM Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105488 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105488&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325444 104001205 CHEMBL96785 ZINC26663907 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015282 OC(CCN1CCC23CCCC[C@H]2[C@H]1Cc1cc(O)ccc31)c1cccs1 InChI=1S/C23H29NO2S/c25-17-6-7-18-16(14-17)15-20-19-4-1-2-9-23(18,19)10-12-24(20)11-8-21(26)22-5-3-13-27-22/h3,5-7,13-14,19-21,25-26H,1-2,4,8-12,15H2/t19-,20+,21?,23?/m0/s1 RBIPSMFEMQGQTP-HUHVMKPBSA-N 50105486 17-[3-hydroxy-3-(2-thienyl)propyl]-(1R,9R,10R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-5-ol::CHEMBL90305::MCL-122 Mu-type opioid receptor Cavia cutleri 4.1 ChEMBL 10.1016/s0960-894x(01)00543-1 10.7270/Q25T3M01 11591513 Neumeyer, JL; Gu, XH; van Vliet, LA; DeNunzio, NJ; Rusovici, DE; Cohen, DJ; Negus, SS; Mello, NK; Bidlack, JM Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105486 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105486&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325202 104001203 CHEMBL90305 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015288 Oc1ccc2c(C[C@@H]3[C@@H]4CCCCC24CCN3Cc2cccs2)c1 InChI=1S/C21H25NOS/c23-16-6-7-18-15(12-16)13-20-19-5-1-2-8-21(18,19)9-10-22(20)14-17-4-3-11-24-17/h3-4,6-7,11-12,19-20,23H,1-2,5,8-10,13-14H2/t19-,20+,21?/m0/s1 UWMDNLJXWAKDBP-MCOCGALXSA-N 50105489 17-(2-furylmethyl)-(1R,9R,10R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-5-ol::CHEMBL329020::MCL-120 Mu-type opioid receptor Cavia cutleri 1.5 ChEMBL 10.1016/s0960-894x(01)00543-1 10.7270/Q25T3M01 11591513 Neumeyer, JL; Gu, XH; van Vliet, LA; DeNunzio, NJ; Rusovici, DE; Cohen, DJ; Negus, SS; Mello, NK; Bidlack, JM Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105489 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105489&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325319 104001206 CHEMBL329020 ZINC26663563 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015292 Oc1ccc2c(C[C@@H]3[C@@H]4CCCCC24CCN3Cc2ccco2)c1 InChI=1S/C21H25NO2/c23-16-6-7-18-15(12-16)13-20-19-5-1-2-8-21(18,19)9-10-22(20)14-17-4-3-11-24-17/h3-4,6-7,11-12,19-20,23H,1-2,5,8-10,13-14H2/t19-,20+,21?/m0/s1 SQBKFFDFHSLEKG-MCOCGALXSA-N 50105474 17-(2-furylmethyl)-(1R,9R,10R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-5-ol::CHEMBL328236::MCL-119 Mu-type opioid receptor Cavia cutleri 0.540000 ChEMBL 10.1016/s0960-894x(01)00543-1 10.7270/Q25T3M01 11591513 Neumeyer, JL; Gu, XH; van Vliet, LA; DeNunzio, NJ; Rusovici, DE; Cohen, DJ; Negus, SS; Mello, NK; Bidlack, JM Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105474&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325320 104001191 CHEMBL328236 ZINC26662888 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015296 CC(C)CN1CCC23CCCC[C@H]2[C@H]1Cc1cc(O)ccc31 InChI=1S/C20H29NO/c1-14(2)13-21-10-9-20-8-4-3-5-18(20)19(21)12-15-11-16(22)6-7-17(15)20/h6-7,11,14,18-19,22H,3-5,8-10,12-13H2,1-2H3/t18-,19+,20?/m0/s1 CRNNZEPXNBVIRH-ABZYKWASSA-N 50105495 17-isobutyl-(1R,9R,10R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-5-ol::CHEMBL420995::MCL-108 Mu-type opioid receptor Cavia cutleri 0.540000 ChEMBL 10.1016/s0960-894x(01)00543-1 10.7270/Q25T3M01 11591513 Neumeyer, JL; Gu, XH; van Vliet, LA; DeNunzio, NJ; Rusovici, DE; Cohen, DJ; Negus, SS; Mello, NK; Bidlack, JM Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105495&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325129 104001212 CHEMBL420995 ZINC26654880 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015306 CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C19H26Cl2N2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17-,18-/m1/s1 VQLPLYSROCPWFF-QZTJIDSGSA-N 50000296 CHEMBL441765::CHEMBL482811::U-50488H::US11492374, ID 1 Mu-type opioid receptor Cavia cutleri 220 ChEMBL 10.1016/s0960-894x(01)00543-1 10.7270/Q25T3M01 11591513 Neumeyer, JL; Gu, XH; van Vliet, LA; DeNunzio, NJ; Rusovici, DE; Cohen, DJ; Negus, SS; Mello, NK; Bidlack, JM Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000296&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036289 103914903 73358 CHEMBL482811CHEMBL441765 1654 C11796 ZINC00643032 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015311 Oc1ccc2c(C[C@@H]3[C@@H]4CCCC[C@]24CCN3C\C=C\I)c1 InChI=1S/C19H24INO/c20-9-3-10-21-11-8-19-7-2-1-4-17(19)18(21)13-14-12-15(22)5-6-16(14)19/h3,5-6,9,12,17-18,22H,1-2,4,7-8,10-11,13H2/b9-3+/t17-,18+,19-/m0/s1 QPBQHWRLVDNKCB-KRTMNNNLSA-N 50451302 CHEMBL2115245 Mu-type opioid receptor Cavia cutleri 0.004800 ChEMBL 10.1016/s0960-894x(01)00543-1 10.7270/Q25T3M01 11591513 Neumeyer, JL; Gu, XH; van Vliet, LA; DeNunzio, NJ; Rusovici, DE; Cohen, DJ; Negus, SS; Mello, NK; Bidlack, JM Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50451302 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50451302&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71454569 225145324 CHEMBL2115245 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015313 Oc1ccc2C[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC#C)c2c1 InChI=1S/C19H23NO/c1-2-10-20-11-9-19-8-4-3-5-16(19)18(20)12-14-6-7-15(21)13-17(14)19/h1,6-7,13,16,18,21H,3-5,8-12H2/t16-,18+,19+/m0/s1 OKICQDFBWUMTDE-QXAKKESOSA-N 50366764 CHEMBL1790045::MCL-117 Mu-type opioid receptor Cavia cutleri 0.003200 ChEMBL 10.1016/s0960-894x(01)00543-1 10.7270/Q25T3M01 11591513 Neumeyer, JL; Gu, XH; van Vliet, LA; DeNunzio, NJ; Rusovici, DE; Cohen, DJ; Negus, SS; Mello, NK; Bidlack, JM Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366764 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366764&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 6602241 160845866 CHEMBL1790045 ZINC53261466 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015317 CN1CC[C@]23CCCC[C@H]2[C@H]1Cc1ccc(O)cc31 InChI=1S/C17H23NO/c1-18-9-8-17-7-3-2-4-14(17)16(18)10-12-5-6-13(19)11-15(12)17/h5-6,11,14,16,19H,2-4,7-10H2,1H3/t14-,16+,17+/m0/s1 JAQUASYNZVUNQP-USXIJHARSA-N 50017233 CHEMBL592::LEVO-DROMORAN::LEVORPHANOL Mu-type opioid receptor Cavia cutleri 0.210000 ChEMBL 10.1016/s0960-894x(01)00543-1 10.7270/Q25T3M01 11591513 Neumeyer, JL; Gu, XH; van Vliet, LA; DeNunzio, NJ; Rusovici, DE; Cohen, DJ; Negus, SS; Mello, NK; Bidlack, JM Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017233 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017233&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5359272 103928501 CHEMBL592 DB00854 C08014 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015319 Oc1ccc2c(C[C@@H]3[C@@H]4CCCCC24CCN3CCc2ccccc2)c1 InChI=1S/C24H29NO/c26-20-9-10-21-19(16-20)17-23-22-8-4-5-12-24(21,22)13-15-25(23)14-11-18-6-2-1-3-7-18/h1-3,6-7,9-10,16,22-23,26H,4-5,8,11-15,17H2/t22-,23+,24?/m0/s1 LSTHMGDZXZATNR-XAGPSQNTSA-N 50105496 17-phenethyl-(1R,9R,10R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-5-ol::CHEMBL327576::MCL-112 Mu-type opioid receptor Cavia cutleri 0.120000 ChEMBL 10.1016/s0960-894x(01)00543-1 10.7270/Q25T3M01 11591513 Neumeyer, JL; Gu, XH; van Vliet, LA; DeNunzio, NJ; Rusovici, DE; Cohen, DJ; Negus, SS; Mello, NK; Bidlack, JM Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105496 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105496&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325455 104001213 CHEMBL327576 ZINC26658995 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015321 Oc1ccc2c(C[C@@H]3[C@@H]4CCCCC24CCN3CCC(=O)c2ccccc2)c1 InChI=1S/C25H29NO2/c27-20-9-10-21-19(16-20)17-23-22-8-4-5-12-25(21,22)13-15-26(23)14-11-24(28)18-6-2-1-3-7-18/h1-3,6-7,9-10,16,22-23,27H,4-5,8,11-15,17H2/t22-,23+,25?/m0/s1 CCQXLGALTORBFA-YGHPRADISA-N 50105490 3-[5-hydroxy-(1R,9R,10R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-17-yl]-1-phenyl-1-propanone::CHEMBL430833::MCL-115 Mu-type opioid receptor Cavia cutleri 0.430000 ChEMBL 10.1016/s0960-894x(01)00543-1 10.7270/Q25T3M01 11591513 Neumeyer, JL; Gu, XH; van Vliet, LA; DeNunzio, NJ; Rusovici, DE; Cohen, DJ; Negus, SS; Mello, NK; Bidlack, JM Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105490 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105490&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325457 104001207 CHEMBL430833 ZINC26664886 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015324 Oc1ccc2c(C[C@@H]3[C@@H]4CCCCC24CCN3CCC(=O)c2cccs2)c1 InChI=1S/C23H27NO2S/c25-17-6-7-18-16(14-17)15-20-19-4-1-2-9-23(18,19)10-12-24(20)11-8-21(26)22-5-3-13-27-22/h3,5-7,13-14,19-20,25H,1-2,4,8-12,15H2/t19-,20+,23?/m0/s1 KQYOUOIJGNIBFU-RCCQNZRSSA-N 50105492 3-[5-hydroxy-(1R,9R,10R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-17-yl]-1-(2-thienyl)-1-propanone::CHEMBL327885::MCL-114 Mu-type opioid receptor Cavia cutleri 0.270000 ChEMBL 10.1016/s0960-894x(01)00543-1 10.7270/Q25T3M01 11591513 Neumeyer, JL; Gu, XH; van Vliet, LA; DeNunzio, NJ; Rusovici, DE; Cohen, DJ; Negus, SS; Mello, NK; Bidlack, JM Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105492 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105492&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325135 104001209 CHEMBL327885 ZINC26664933 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015325 COCCN1CCC23CCCC[C@H]2[C@H]1Cc1cc(O)ccc31 InChI=1S/C19H27NO2/c1-22-11-10-20-9-8-19-7-3-2-4-17(19)18(20)13-14-12-15(21)5-6-16(14)19/h5-6,12,17-18,21H,2-4,7-11,13H2,1H3/t17-,18+,19?/m0/s1 RXJLPWXRPNCGLY-PAMZHZACSA-N 50105477 17-(2-methoxyethyl)-(1R,9R,10R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-5-ol::CHEMBL90667::MCL-110 Mu-type opioid receptor Cavia cutleri 0.110000 ChEMBL 10.1016/s0960-894x(01)00543-1 10.7270/Q25T3M01 11591513 Neumeyer, JL; Gu, XH; van Vliet, LA; DeNunzio, NJ; Rusovici, DE; Cohen, DJ; Negus, SS; Mello, NK; Bidlack, JM Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105477 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105477&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325133 104001194 CHEMBL90667 ZINC26652122 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015326 Oc1ccc2c(C[C@@H]3[C@@H]4CCCCC24CCN3CC=C)c1 InChI=1S/C19H25NO/c1-2-10-20-11-9-19-8-4-3-5-17(19)18(20)13-14-12-15(21)6-7-16(14)19/h2,6-7,12,17-18,21H,1,3-5,8-11,13H2/t17-,18+,19?/m0/s1 SISVKKMIVGWPLL-PAMZHZACSA-N 50105491 17-allyl-(1R,9R,10R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-5-ol::CHEMBL328269::MCL-113 Mu-type opioid receptor Cavia cutleri 0.340000 ChEMBL 10.1016/s0960-894x(01)00543-1 10.7270/Q25T3M01 11591513 Neumeyer, JL; Gu, XH; van Vliet, LA; DeNunzio, NJ; Rusovici, DE; Cohen, DJ; Negus, SS; Mello, NK; Bidlack, JM Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105491 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105491&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325134 104001208 CHEMBL328269 ZINC26652127 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015328 Oc1ccc2c(C[C@@H]3[C@@H]4CCCCC24CCN3CCOc2ccccc2)c1 InChI=1S/C24H29NO2/c26-19-9-10-21-18(16-19)17-23-22-8-4-5-11-24(21,22)12-13-25(23)14-15-27-20-6-2-1-3-7-20/h1-3,6-7,9-10,16,22-23,26H,4-5,8,11-15,17H2/t22-,23+,24?/m0/s1 ANPFDZVJMUWEGU-XAGPSQNTSA-N 50105478 17-(2-phenoxyethyl)-(1R,9R,10R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-5-ol::CHEMBL92774::MCL-127 Mu-type opioid receptor Cavia cutleri 0.920000 ChEMBL 10.1016/s0960-894x(01)00543-1 10.7270/Q25T3M01 11591513 Neumeyer, JL; Gu, XH; van Vliet, LA; DeNunzio, NJ; Rusovici, DE; Cohen, DJ; Negus, SS; Mello, NK; Bidlack, JM Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105478 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105478&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325216 104001195 CHEMBL92774 ZINC26663572 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015330 OC(CCN1CCC23CCCC[C@H]2[C@H]1Cc1cc(O)ccc31)c1ccco1 InChI=1S/C23H29NO3/c25-17-6-7-18-16(14-17)15-20-19-4-1-2-9-23(18,19)10-12-24(20)11-8-21(26)22-5-3-13-27-22/h3,5-7,13-14,19-21,25-26H,1-2,4,8-12,15H2/t19-,20+,21?,23?/m0/s1 QKTRBTWYSXCKTF-HUHVMKPBSA-N 50105484 1-(2-furyl)-3-[5-hydroxy-(1R,9R,10R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-17-yl]-1-propanol::CHEMBL327490::MCL-128 Mu-type opioid receptor Cavia cutleri 4.2 ChEMBL 10.1016/s0960-894x(01)00543-1 10.7270/Q25T3M01 11591513 Neumeyer, JL; Gu, XH; van Vliet, LA; DeNunzio, NJ; Rusovici, DE; Cohen, DJ; Negus, SS; Mello, NK; Bidlack, JM Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105484&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325215 104001201 CHEMBL327490 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015338 Oc1ccc2c(C[C@@H]3[C@@H]4CCCCC24CCN3CCC(=O)c2ccco2)c1 InChI=1S/C23H27NO3/c25-17-6-7-18-16(14-17)15-20-19-4-1-2-9-23(18,19)10-12-24(20)11-8-21(26)22-5-3-13-27-22/h3,5-7,13-14,19-20,25H,1-2,4,8-12,15H2/t19-,20+,23?/m0/s1 YBXNDQIEEVILNJ-RCCQNZRSSA-N 50105493 1-(2-furyl)-3-[5-hydroxy-(1R,9R,10R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-17-yl]-1-propanone::CHEMBL91231::MCL-123 Mu-type opioid receptor Cavia cutleri 0.280000 ChEMBL 10.1016/s0960-894x(01)00543-1 10.7270/Q25T3M01 11591513 Neumeyer, JL; Gu, XH; van Vliet, LA; DeNunzio, NJ; Rusovici, DE; Cohen, DJ; Negus, SS; Mello, NK; Bidlack, JM Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105493&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325181 104001210 CHEMBL91231 ZINC26652397 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015340 Oc1ccc2c(C[C@@H]3[C@@H]4CCCC[C@]24CCN3C\C=C/I)c1 InChI=1S/C19H24INO/c20-9-3-10-21-11-8-19-7-2-1-4-17(19)18(21)13-14-12-15(22)5-6-16(14)19/h3,5-6,9,12,17-18,22H,1-2,4,7-8,10-11,13H2/b9-3-/t17-,18+,19-/m0/s1 QPBQHWRLVDNKCB-PLVMTXDNSA-N 50451303 CHEMBL2114257::MCL-116 Mu-type opioid receptor Cavia cutleri 0.420000 ChEMBL 10.1016/s0960-894x(01)00543-1 10.7270/Q25T3M01 11591513 Neumeyer, JL; Gu, XH; van Vliet, LA; DeNunzio, NJ; Rusovici, DE; Cohen, DJ; Negus, SS; Mello, NK; Bidlack, JM Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50451303 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50451303&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71454539 225145325 CHEMBL2114257 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015341 Oc1ccc2c(C[C@@H]3[C@@H]4CCCCC24CCN3CCC(F)(F)F)c1 InChI=1S/C19H24F3NO/c20-19(21,22)8-10-23-9-7-18-6-2-1-3-16(18)17(23)12-13-11-14(24)4-5-15(13)18/h4-5,11,16-17,24H,1-3,6-10,12H2/t16-,17+,18?/m0/s1 JVDYHGRJOLGWFV-MYFVLZFPSA-N 50105487 17-(3,3,3-trifluoropropyl)-(1R,9R,10R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-5-ol::CHEMBL314294::MCL-124 Mu-type opioid receptor Cavia cutleri 2.3 ChEMBL 10.1016/s0960-894x(01)00543-1 10.7270/Q25T3M01 11591513 Neumeyer, JL; Gu, XH; van Vliet, LA; DeNunzio, NJ; Rusovici, DE; Cohen, DJ; Negus, SS; Mello, NK; Bidlack, JM Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105487 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105487&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325180 104001204 CHEMBL314294 ZINC26652392 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015342 CCOCCN1CCC23CCCC[C@H]2[C@H]1Cc1cc(O)ccc31 InChI=1S/C20H29NO2/c1-2-23-12-11-21-10-9-20-8-4-3-5-18(20)19(21)14-15-13-16(22)6-7-17(15)20/h6-7,13,18-19,22H,2-5,8-12,14H2,1H3/t18-,19+,20?/m0/s1 AKYMKOCEELSTOI-ABZYKWASSA-N 50105481 17-(2-ethoxyethyl)-(1R,9R,10R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-5-ol::CHEMBL90463::MCL-109 Mu-type opioid receptor Cavia cutleri 0.260000 ChEMBL 10.1016/s0960-894x(01)00543-1 10.7270/Q25T3M01 11591513 Neumeyer, JL; Gu, XH; van Vliet, LA; DeNunzio, NJ; Rusovici, DE; Cohen, DJ; Negus, SS; Mello, NK; Bidlack, JM Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105481 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105481&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325125 104001198 CHEMBL90463 ZINC26650106 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015345 Oc1ccc2c(C[C@@H]3[C@@H]4CCCCC24CCN3CCCF)c1 InChI=1S/C19H26FNO/c20-9-3-10-21-11-8-19-7-2-1-4-17(19)18(21)13-14-12-15(22)5-6-16(14)19/h5-6,12,17-18,22H,1-4,7-11,13H2/t17-,18+,19?/m0/s1 BPUIXKIABUVKTM-PAMZHZACSA-N 50105498 17-(3-fluoropropyl)-(1R,9R,10R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-5-ol::CHEMBL419511 Mu-type opioid receptor Cavia cutleri 0.180000 ChEMBL 10.1016/s0960-894x(01)00543-1 10.7270/Q25T3M01 11591513 Neumeyer, JL; Gu, XH; van Vliet, LA; DeNunzio, NJ; Rusovici, DE; Cohen, DJ; Negus, SS; Mello, NK; Bidlack, JM Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105498 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105498&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325138 104001215 CHEMBL419511 ZINC26655190 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015347 Oc1ccc2c(C[C@@H]3[C@@H]4CCCCC24CCN3CC2CCCCC2)c1 InChI=1S/C23H33NO/c25-19-9-10-20-18(14-19)15-22-21-8-4-5-11-23(20,21)12-13-24(22)16-17-6-2-1-3-7-17/h9-10,14,17,21-22,25H,1-8,11-13,15-16H2/t21-,22+,23?/m0/s1 GBFHSQJNPGVNMH-ZVTBYLAHSA-N 50105494 17-(N-cyclohexylmethyl)-(1R,9R,10R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-5-ol::CHEMBL329453::MCL-105 Mu-type opioid receptor Cavia cutleri 18 ChEMBL 10.1016/s0960-894x(01)00543-1 10.7270/Q25T3M01 11591513 Neumeyer, JL; Gu, XH; van Vliet, LA; DeNunzio, NJ; Rusovici, DE; Cohen, DJ; Negus, SS; Mello, NK; Bidlack, JM Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105494 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105494&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325124 104001211 CHEMBL329453 ZINC26650102 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015348 Oc1ccc2c(C[C@@H]3[C@@H]4CCCCC24CCN3CC2CCCC2)c1 InChI=1S/C22H31NO/c24-18-8-9-19-17(13-18)14-21-20-7-3-4-10-22(19,20)11-12-23(21)15-16-5-1-2-6-16/h8-9,13,16,20-21,24H,1-7,10-12,14-15H2/t20-,21+,22?/m0/s1 IWDZOLLSPCEXLJ-UGGDCYSXSA-N 50105485 17-cyclopentylmethyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-5-ol::CHEMBL327309::MCL-104 Mu-type opioid receptor Cavia cutleri 0.960000 ChEMBL 10.1016/s0960-894x(01)00543-1 10.7270/Q25T3M01 11591513 Neumeyer, JL; Gu, XH; van Vliet, LA; DeNunzio, NJ; Rusovici, DE; Cohen, DJ; Negus, SS; Mello, NK; Bidlack, JM Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105485 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105485&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325139 104001202 CHEMBL327309 ZINC26655195 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50017473 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3Cc1c4[nH]c2ccccc12)ccc5O InChI=1S/C23H22N2O2/c1-25-9-8-23-15-11-14-13-4-2-3-5-16(13)24-20(14)22(23)27-21-18(26)7-6-12(19(21)23)10-17(15)25/h2-7,15,17,22,24,26H,8-11H2,1H3/t15-,17+,22-,23-/m0/s1 LGKQZPYRRAWJJB-JOXUJNMQSA-N 50451441 CHEMBL607396 Mu-type opioid receptor Cavia cutleri 202 ChEMBL 10.1016/s0960-894x(01)00689-8 10.7270/Q2S181T9 11755345 Yu, H; Prisinzano, T; Dersch, CM; Marcus, J; Rothman, RB; Jacobson, AE; Rice, KC NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50451441 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50451441&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10046193 225145365 CHEMBL607396 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50017478 COc1ccc2CC3C4[C@@H](C)c5c([nH]c6ccccc56)[C@@H]5Oc1c2C45CCN3C InChI=1S/C25H26N2O2/c1-13-19-15-6-4-5-7-16(15)26-22(19)24-25-10-11-27(2)17(20(13)25)12-14-8-9-18(28-3)23(29-24)21(14)25/h4-9,13,17,20,24,26H,10-12H2,1-3H3/t13-,17?,20?,24-,25?/m0/s1 CQDVKAKVXRIKJR-MHWYGFRSSA-N 50108348 CHEMBL296922::Indole Derivative Mu-type opioid receptor Cavia cutleri >600 ChEMBL 10.1016/s0960-894x(01)00689-8 10.7270/Q2S181T9 11755345 Yu, H; Prisinzano, T; Dersch, CM; Marcus, J; Rothman, RB; Jacobson, AE; Rice, KC NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108348 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108348&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44291332 104003567 CHEMBL296922 ZINC36221786 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50017483 CCCC[C@@H]1C2C3Cc4ccc(O)c5O[C@@H](c6[nH]c7ccccc7c16)C2(CCN3C)c45 InChI=1S/C27H30N2O2/c1-3-4-7-17-21-16-8-5-6-9-18(16)28-24(21)26-27-12-13-29(2)19(23(17)27)14-15-10-11-20(30)25(31-26)22(15)27/h5-6,8-11,17,19,23,26,28,30H,3-4,7,12-14H2,1-2H3/t17-,19?,23?,26-,27?/m0/s1 YLFVOHQBMMEFKC-MWKAYASPSA-N 50108349 CHEMBL297839::Indole Derivative Mu-type opioid receptor Cavia cutleri 561 ChEMBL 10.1016/s0960-894x(01)00689-8 10.7270/Q2S181T9 11755345 Yu, H; Prisinzano, T; Dersch, CM; Marcus, J; Rothman, RB; Jacobson, AE; Rice, KC NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108349&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44291655 104003568 CHEMBL297839 ZINC36221071 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50017485 CCCC[C@@H]1C2C3Cc4ccc(OC)c5O[C@@H](c6[nH]c7ccccc7c16)C2(CCN3C)c45 InChI=1S/C28H32N2O2/c1-4-5-8-18-22-17-9-6-7-10-19(17)29-25(22)27-28-13-14-30(2)20(24(18)28)15-16-11-12-21(31-3)26(32-27)23(16)28/h6-7,9-12,18,20,24,27,29H,4-5,8,13-15H2,1-3H3/t18-,20?,24?,27-,28?/m0/s1 RJLOZLWGWXBUEL-QPQQZKPTSA-N 50108347 CHEMBL432117::Indole Derivative Mu-type opioid receptor Cavia cutleri >600 ChEMBL 10.1016/s0960-894x(01)00689-8 10.7270/Q2S181T9 11755345 Yu, H; Prisinzano, T; Dersch, CM; Marcus, J; Rothman, RB; Jacobson, AE; Rice, KC NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108347&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44291354 104003566 CHEMBL432117 ZINC40817954 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50017491 COc1ccc2CC3C4Cc5c([nH]c6ccccc56)[C@@H]5Oc1c2C45CCN3C InChI=1S/C24H24N2O2/c1-26-10-9-24-16-12-15-14-5-3-4-6-17(14)25-21(15)23(24)28-22-19(27-2)8-7-13(20(22)24)11-18(16)26/h3-8,16,18,23,25H,9-12H2,1-2H3/t16?,18?,23-,24?/m0/s1 JUUYNFHQKQIBCF-QDPSRHSWSA-N 50108351 CHEMBL45344::Indole Derivative Mu-type opioid receptor Cavia cutleri >600 ChEMBL 10.1016/s0960-894x(01)00689-8 10.7270/Q2S181T9 11755345 Yu, H; Prisinzano, T; Dersch, CM; Marcus, J; Rothman, RB; Jacobson, AE; Rice, KC NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108351&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44291264 104003570 CHEMBL45344 ZINC29404880 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50017494 C[C@@H]1C2C3Cc4ccc(O)c5O[C@@H](c6[nH]c7ccccc7c16)C2(CCN3C)c45 InChI=1S/C24H24N2O2/c1-12-18-14-5-3-4-6-15(14)25-21(18)23-24-9-10-26(2)16(19(12)24)11-13-7-8-17(27)22(28-23)20(13)24/h3-8,12,16,19,23,25,27H,9-11H2,1-2H3/t12-,16?,19?,23-,24?/m0/s1 BKKGVUYVPORNKS-GAQQVJAQSA-N 50108346 CHEMBL295295::Indole Derivative Mu-type opioid receptor Cavia cutleri >600 ChEMBL 10.1016/s0960-894x(01)00689-8 10.7270/Q2S181T9 11755345 Yu, H; Prisinzano, T; Dersch, CM; Marcus, J; Rothman, RB; Jacobson, AE; Rice, KC NIDDK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108346&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44291256 104003565 CHEMBL295295 ZINC36221062 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015495 CNC(Cc1ccc(O)cc1)C(=O)NCC(=O)NCC(=O)NC(Cc1ccc(cc1)[N+]([O-])=O)C(=O)NC(CC(C)C)C(=O)NC(CCC[N-]C(N)=[NH2+])C(=O)NC(CCC[N-]C(N)=[NH2+])C(=O)NC(CC(C)C)C(N)=O InChI=1S/C47H74N16O11/c1-26(2)20-34(40(48)67)61-43(70)33(9-7-19-55-47(51)52)59-42(69)32(8-6-18-54-46(49)50)60-44(71)36(21-27(3)4)62-45(72)37(23-28-10-14-30(15-11-28)63(73)74)58-39(66)25-56-38(65)24-57-41(68)35(53-5)22-29-12-16-31(64)17-13-29/h10-17,26-27,32-37,53H,6-9,18-25H2,1-5H3,(H18,48,49,50,51,52,54,55,56,57,58,59,60,61,62,64,65,66,67,68,69,70,71,72) RKKYQSUGOCWQRV-UHFFFAOYSA-N 50010542 2-[5-Guanidino-2-(5-guanidino-2-{2-[2-(2-{2-[3-(4-hydroxy-phenyl)-2-methylamino-propionylamino]-acetylamino}-acetylamino)-3-(4-nitro-phenyl)-propionylamino]-4-methyl-pentanoylamino}-pentanoylamino)-pentanoylamino]-4-methyl-pentanoic acid amide::CHEMBL410611 Mu-type opioid receptor Cavia cutleri 1 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010542 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010542&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 13935836 103923318 CHEMBL410611 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015497 CCNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)N(C)C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H]1CSSC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N1 InChI=1S/C47H73N15O9S2/c1-5-53-40(66)33(21-27(2)3)59-44(70)37(14-10-20-55-47(51)52)62(4)45(71)32(13-9-19-54-46(49)50)58-43(69)36-26-73-72-25-35(60-39(65)31(48)22-29-15-17-30(63)18-16-29)41(67)56-24-38(64)57-34(42(68)61-36)23-28-11-7-6-8-12-28/h6-8,11-12,15-18,27,31-37,63H,5,9-10,13-14,19-26,48H2,1-4H3,(H,53,66)(H,56,67)(H,57,64)(H,58,69)(H,59,70)(H,60,65)(H,61,68)(H4,49,50,54)(H4,51,52,55)/t31-,32-,33-,34+,35-,36+,37-/m0/s1 UQHCMUXJGZRDTC-ADYVUFBVSA-N 50010532 13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid (1-{[1-(1-ethylcarbamoyl-3-methyl-butylcarbamoyl)-4-guanidino-butyl]-methyl-carbamoyl}-4-guanidino-butyl)-amide::CHEMBL441939 Mu-type opioid receptor Cavia cutleri 0.850000 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010532 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010532&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44306943 103923308 CHEMBL441939 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015498 CCCCCCNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC InChI=1S/C53H87N15O9/c1-7-8-9-13-24-59-47(73)41(27-33(2)3)67-49(75)39(19-15-26-61-53(56)57)65-48(74)38(18-14-25-60-52(54)55)66-50(76)42(28-34(4)5)68-51(77)43(30-35-16-11-10-12-17-35)64-45(71)32-62-44(70)31-63-46(72)40(58-6)29-36-20-22-37(69)23-21-36/h10-12,16-17,20-23,33-34,38-43,58,69H,7-9,13-15,18-19,24-32H2,1-6H3,(H,59,73)(H,62,70)(H,63,72)(H,64,71)(H,65,74)(H,66,76)(H,67,75)(H,68,77)(H4,54,55,60)(H4,56,57,61)/t38-,39-,40-,41-,42-,43+/m0/s1 TYPIRBLTBYFROQ-YATXZJLRSA-N 50010548 2-[2-(2-{2-[3-(4-Hydroxy-phenyl)-2-methylamino-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid {4-guanidino-1-[4-guanidino-1-(1-hexylcarbamoyl-3-methyl-butylcarbamoyl)-butylcarbamoyl]-butyl}-amide::CHEMBL412769 Mu-type opioid receptor Cavia cutleri 6.6 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010548 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010548&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44307185 103923324 CHEMBL412769 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015499 CCNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)N(C)C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC InChI=1S/C50H81N15O9/c1-8-56-44(70)37(24-30(2)3)64-47(73)40(17-13-23-58-50(53)54)65(7)48(74)35(16-12-22-57-49(51)52)62-45(71)38(25-31(4)5)63-46(72)39(27-32-14-10-9-11-15-32)61-42(68)29-59-41(67)28-60-43(69)36(55-6)26-33-18-20-34(66)21-19-33/h9-11,14-15,18-21,30-31,35-40,55,66H,8,12-13,16-17,22-29H2,1-7H3,(H,56,70)(H,59,67)(H,60,69)(H,61,68)(H,62,71)(H,63,72)(H,64,73)(H4,51,52,57)(H4,53,54,58)/t35-,36-,37-,38-,39+,40-/m0/s1 JENWDDCMEATQSR-NGXVWMITSA-N 50010534 2-[2-(2-{2-[3-(4-Hydroxy-phenyl)-2-methylamino-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid (1-{[1-(1-ethylcarbamoyl-3-methyl-butylcarbamoyl)-4-guanidino-butyl]-methyl-carbamoyl}-4-guanidino-butyl)-amide::CHEMBL412325 Mu-type opioid receptor Cavia cutleri 0.300000 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010534&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44306952 103923310 CHEMBL412325 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015504 CCNC(=O)C(CC(C)C)NC(=O)C(CCC[N-]C(N)=[NH2+])N(C)C(=O)C(CCC[N-]C(N)=[NH2+])NC(=O)C(CC(C)C)NC(=O)C(Cc1ccc(cc1)[N+]([O-])=O)NC(=O)CNC(=O)CNC(=O)C(Cc1ccc(O)cc1)NC InChI=1S/C50H80N16O11/c1-8-56-44(71)37(23-29(2)3)64-47(74)40(12-10-22-58-50(53)54)65(7)48(75)35(11-9-21-57-49(51)52)62-45(72)38(24-30(4)5)63-46(73)39(26-31-13-17-33(18-14-31)66(76)77)61-42(69)28-59-41(68)27-60-43(70)36(55-6)25-32-15-19-34(67)20-16-32/h13-20,29-30,35-40,55H,8-12,21-28H2,1-7H3,(H16,51,52,53,54,56,57,58,59,60,61,62,63,64,67,68,69,70,71,72,73,74) WERDBVWQNIXFQM-UHFFFAOYSA-N 50010545 2-{5-Guanidino-2-[(5-guanidino-2-{2-[2-(2-{2-[3-(4-hydroxy-phenyl)-2-methylamino-propionylamino]-acetylamino}-acetylamino)-3-(4-nitro-phenyl)-propionylamino]-4-methyl-pentanoylamino}-pentanoyl)-methyl-amino]-pentanoylamino}-4-methyl-pentanoic acidN-ethyl amide::CHEMBL415410 Mu-type opioid receptor Cavia cutleri 0.500000 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010545 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010545&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14015071 103923321 CHEMBL415410 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50014437 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C75H126N24O15/c1-7-45(6)61(70(111)94-53(25-17-35-87-75(83)84)71(112)99-36-18-26-58(99)69(110)93-50(21-11-13-31-76)64(105)96-56(38-44(4)5)67(108)95-54(72(113)114)22-12-14-32-77)98-65(106)52(24-16-34-86-74(81)82)91-63(104)51(23-15-33-85-73(79)80)92-66(107)55(37-43(2)3)97-68(109)57(40-46-19-9-8-10-20-46)90-60(102)42-88-59(101)41-89-62(103)49(78)39-47-27-29-48(100)30-28-47/h8-10,19-20,27-30,43-45,49-58,61,100H,7,11-18,21-26,31-42,76-78H2,1-6H3,(H,88,101)(H,89,103)(H,90,102)(H,91,104)(H,92,107)(H,93,110)(H,94,111)(H,95,108)(H,96,105)(H,97,109)(H,98,106)(H,113,114)(H4,79,80,85)(H4,81,82,86)(H4,83,84,87)/t45-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,61-/m0/s1 OVVIBUHLQIYUEU-IWIISZHXSA-N 224024 BDBM50241435::Dynorphin A (1-13)::YGGFLRRXRPKLK Mu-type opioid receptor Cavia cutleri 50 ChEMBL 10.1021/jm00113a020 10.7270/Q2J965CZ 1895300 Jacobson, AR; Tam, SW; Sayre, LM Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=224024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=224024&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25075996 374884564 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50014439 NCCCC(=O)NCCN(CCN(CCNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)CCCN)C(=O)CCCN InChI=1S/C40H63N11O8/c41-16-4-9-34(53)45-19-21-50(37(56)10-5-17-42)23-24-51(38(57)11-6-18-43)22-20-46-40(59)33(26-29-7-2-1-3-8-29)49-36(55)28-47-35(54)27-48-39(58)32(44)25-30-12-14-31(52)15-13-30/h1-3,7-8,12-15,32-33,52H,4-6,9-11,16-28,41-44H2,(H,45,53)(H,46,59)(H,47,54)(H,48,58)(H,49,55)/t32-,33-/m0/s1 SPSACABOQXSKTD-LQJZCPKCSA-N 50009674 4-Amino-N-[2-(4-amino-butyrylamino)-ethyl]-N-[2-((4-amino-butyryl)-{2-[2-(2-{2-[2-amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-ethyl}-amino)-ethyl]-butyramide::CHEMBL97363 Mu-type opioid receptor Cavia cutleri 6760 ChEMBL 10.1021/jm00113a020 10.7270/Q2J965CZ 1895300 Jacobson, AR; Tam, SW; Sayre, LM Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009674 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009674&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15689712 103922657 CHEMBL97363 ZINC95545776 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50014440 NCCCC(=O)NCCCN(CCCNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)CCCN InChI=1S/C36H55N9O7/c37-16-4-10-31(47)40-18-6-20-45(34(50)11-5-17-38)21-7-19-41-36(52)30(23-26-8-2-1-3-9-26)44-33(49)25-42-32(48)24-43-35(51)29(39)22-27-12-14-28(46)15-13-27/h1-3,8-9,12-15,29-30,46H,4-7,10-11,16-25,37-39H2,(H,40,47)(H,41,52)(H,42,48)(H,43,51)(H,44,49)/t29-,30-/m0/s1 YPNDWRKTDJSWBU-KYJUHHDHSA-N 50009677 4-Amino-N-[3-(4-amino-butyrylamino)-propyl]-N-{3-[2-(2-{2-[2-amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-propyl}-butyramide::CHEMBL94792 Mu-type opioid receptor Cavia cutleri 7300 ChEMBL 10.1021/jm00113a020 10.7270/Q2J965CZ 1895300 Jacobson, AR; Tam, SW; Sayre, LM Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009677 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009677&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15689718 103922659 CHEMBL94792 ZINC26716365 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50014441 NCCCC(=O)NCCNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C28H39N7O6/c29-12-4-7-24(37)31-13-14-32-28(41)23(16-19-5-2-1-3-6-19)35-26(39)18-33-25(38)17-34-27(40)22(30)15-20-8-10-21(36)11-9-20/h1-3,5-6,8-11,22-23,36H,4,7,12-18,29-30H2,(H,31,37)(H,32,41)(H,33,38)(H,34,40)(H,35,39)/t22-,23-/m0/s1 OXTLPCYBROBSBS-GOTSBHOMSA-N 50009676 4-Amino-N-{2-[2-(2-{2-[2-amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-ethyl}-butyramide::CHEMBL412591 Mu-type opioid receptor Cavia cutleri 16500 ChEMBL 10.1021/jm00113a020 10.7270/Q2J965CZ 1895300 Jacobson, AR; Tam, SW; Sayre, LM Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009676 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009676&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15689703 103922658 CHEMBL412591 ZINC26675313 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50014443 NCCCC(=O)NCCN(CCNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)CCCN InChI=1S/C34H51N9O7/c35-14-4-8-29(45)38-16-18-43(32(48)9-5-15-36)19-17-39-34(50)28(21-24-6-2-1-3-7-24)42-31(47)23-40-30(46)22-41-33(49)27(37)20-25-10-12-26(44)13-11-25/h1-3,6-7,10-13,27-28,44H,4-5,8-9,14-23,35-37H2,(H,38,45)(H,39,50)(H,40,46)(H,41,49)(H,42,47)/t27-,28-/m0/s1 URWIFQGNZJDWHF-NSOVKSMOSA-N 50009678 4-Amino-N-[2-(4-amino-butyrylamino)-ethyl]-N-{2-[2-(2-{2-[2-amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-ethyl}-butyramide::CHEMBL98014 Mu-type opioid receptor Cavia cutleri 14400 ChEMBL 10.1021/jm00113a020 10.7270/Q2J965CZ 1895300 Jacobson, AR; Tam, SW; Sayre, LM Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009678 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009678&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15689709 103922660 CHEMBL98014 ZINC26718363 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015522 CN[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)NCC(=O)N(C)[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(N)=O InChI=1S/C48H77N15O9/c1-28(2)22-35(41(49)67)61-44(70)34(15-11-21-56-48(52)53)59-43(69)33(14-10-20-55-47(50)51)60-45(71)37(23-29(3)4)62-46(72)38(25-30-12-8-7-9-13-30)63(6)40(66)27-57-39(65)26-58-42(68)36(54-5)24-31-16-18-32(64)19-17-31/h7-9,12-13,16-19,28-29,33-38,54,64H,10-11,14-15,20-27H2,1-6H3,(H2,49,67)(H,57,65)(H,58,68)(H,59,69)(H,60,71)(H,61,70)(H,62,72)(H4,50,51,55)(H4,52,53,56)/t33-,34-,35-,36-,37-,38-/m0/s1 KBYBJHQGCXOQQA-JPRYDEJLSA-N 50010544 2-{5-Guanidino-2-[5-guanidino-2-(2-{2-[(2-{2-[3-(4-hydroxy-phenyl)-2-methylamino-propionylamino]-acetylamino}-acetyl)-methyl-amino]-3-phenyl-propionylamino}-4-methyl-pentanoylamino)-pentanoylamino]-pentanoylamino}-4-methyl-pentanoic acid amide::CHEMBL428803 Mu-type opioid receptor Cavia cutleri 27 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010544 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010544&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44307076 103923320 CHEMBL428803 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015531 CN[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)NCC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N(C)[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(N)=O InChI=1S/C48H77N15O9/c1-28(2)22-34(41(49)67)61-43(69)33(14-10-20-55-47(50)51)60-45(71)38(15-11-21-56-48(52)53)63(6)46(72)37(23-29(3)4)62-44(70)36(25-30-12-8-7-9-13-30)59-40(66)27-57-39(65)26-58-42(68)35(54-5)24-31-16-18-32(64)19-17-31/h7-9,12-13,16-19,28-29,33-38,54,64H,10-11,14-15,20-27H2,1-6H3,(H2,49,67)(H,57,65)(H,58,68)(H,59,66)(H,60,71)(H,61,69)(H,62,70)(H4,50,51,55)(H4,52,53,56)/t33-,34-,35-,36+,37-,38-/m0/s1 KGKKWKUNVUXSTK-ZPRVLUMXSA-N 50010546 2-{5-Guanidino-2-[5-guanidino-2-({2-[2-(2-{2-[3-(4-hydroxy-phenyl)-2-methylamino-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoyl}-methyl-amino)-pentanoylamino]-pentanoylamino}-4-methyl-pentanoic acid amide::CHEMBL429020 Mu-type opioid receptor Cavia cutleri 21 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010546 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010546&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44307319 103923322 CHEMBL429020 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015534 CN[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)NCC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(N)=O InChI=1S/C48H77N15O9/c1-28(2)22-35(41(49)67)62-44(70)34(15-11-21-56-48(52)53)60-43(69)33(14-9-10-20-55-47(50)51)61-45(71)37(23-29(3)4)63-46(72)38(25-30-12-7-6-8-13-30)59-40(66)27-57-39(65)26-58-42(68)36(54-5)24-31-16-18-32(64)19-17-31/h6-8,12-13,16-19,28-29,33-38,54,64H,9-11,14-15,20-27H2,1-5H3,(H2,49,67)(H,57,65)(H,58,68)(H,59,66)(H,60,69)(H,61,71)(H,62,70)(H,63,72)(H4,50,51,55)(H4,52,53,56)/t33-,34-,35-,36-,37-,38+/m0/s1 YPCYGLJCQYXZJX-RHIIWVEJSA-N 50010543 6-Guanidino-2-{2-[2-(2-{2-[3-(4-hydroxy-phenyl)-2-methylamino-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-hexanoic acid [1-(1-carbamoyl-3-methyl-butylcarbamoyl)-4-guanidino-butyl]-amide::CHEMBL408557 Mu-type opioid receptor Cavia cutleri 2.6 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010543&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44307320 103923319 CHEMBL408557 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015537 CCNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC InChI=1S/C49H79N15O9/c1-7-55-43(69)37(23-29(2)3)63-45(71)35(16-12-22-57-49(52)53)61-44(70)34(15-11-21-56-48(50)51)62-46(72)38(24-30(4)5)64-47(73)39(26-31-13-9-8-10-14-31)60-41(67)28-58-40(66)27-59-42(68)36(54-6)25-32-17-19-33(65)20-18-32/h8-10,13-14,17-20,29-30,34-39,54,65H,7,11-12,15-16,21-28H2,1-6H3,(H,55,69)(H,58,66)(H,59,68)(H,60,67)(H,61,70)(H,62,72)(H,63,71)(H,64,73)(H4,50,51,56)(H4,52,53,57)/t34-,35-,36-,37-,38-,39+/m0/s1 QQHUSDFMKMTFJA-HBRWQXLPSA-N 50010540 2-[2-(2-{2-[3-(4-Hydroxy-phenyl)-2-methylamino-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid {1-[1-(1-ethylcarbamoyl-3-methyl-butylcarbamoyl)-4-guanidino-butylcarbamoyl]-4-guanidino-butyl}-amide::CHEMBL268105 Mu-type opioid receptor Cavia cutleri 0.700000 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010540 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010540&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44307317 103923316 CHEMBL268105 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015538 CN[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)NCC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(C)[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(N)=O InChI=1S/C48H77N15O9/c1-28(2)22-34(41(49)67)61-45(71)38(15-11-21-56-48(52)53)63(6)46(72)33(14-10-20-55-47(50)51)60-43(69)36(23-29(3)4)62-44(70)37(25-30-12-8-7-9-13-30)59-40(66)27-57-39(65)26-58-42(68)35(54-5)24-31-16-18-32(64)19-17-31/h7-9,12-13,16-19,28-29,33-38,54,64H,10-11,14-15,20-27H2,1-6H3,(H2,49,67)(H,57,65)(H,58,68)(H,59,66)(H,60,69)(H,61,71)(H,62,70)(H4,50,51,55)(H4,52,53,56)/t33-,34-,35-,36-,37+,38-/m0/s1 ZXAIDFHVAANNKH-WRQFUQGOSA-N 50010535 2-{5-Guanidino-2-[(5-guanidino-2-{2-[2-(2-{2-[3-(4-hydroxy-phenyl)-2-methylamino-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-pentanoyl)-methyl-amino]-pentanoylamino}-4-methyl-pentanoic acid amide::CHEMBL266035 Mu-type opioid receptor Cavia cutleri 0.500000 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010535 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010535&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44307318 103923311 CHEMBL266035 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015541 CN[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(N)=O InChI=1S/C48H77N15O9/c1-27(2)22-35(40(49)66)62-43(69)34(15-11-21-56-48(52)53)60-42(68)33(14-10-20-55-47(50)51)61-45(71)37(23-28(3)4)63-46(72)38(25-30-12-8-7-9-13-30)59-39(65)26-57-41(67)29(5)58-44(70)36(54-6)24-31-16-18-32(64)19-17-31/h7-9,12-13,16-19,27-29,33-38,54,64H,10-11,14-15,20-26H2,1-6H3,(H2,49,66)(H,57,67)(H,58,70)(H,59,65)(H,60,68)(H,61,71)(H,62,69)(H,63,72)(H4,50,51,55)(H4,52,53,56)/t29-,33-,34-,35-,36-,37-,38-/m0/s1 LBTOPPHBIVWGRP-AVTNSMPVSA-N 50010537 2-[5-Guanidino-2-(5-guanidino-2-{2-[2-(2-{2-[3-(4-hydroxy-phenyl)-2-methylamino-propionylamino]-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-pentanoylamino)-pentanoylamino]-4-methyl-pentanoic acid amide::CHEMBL266845 Mu-type opioid receptor Cavia cutleri 1.3 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010537 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010537&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44307168 103923313 CHEMBL266845 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015547 CC(C)C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CN(C)C(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O InChI=1S/C47H75N15O9/c1-27(2)21-35(40(49)66)60-42(68)34(14-10-20-55-47(52)53)58-41(67)33(13-9-19-54-46(50)51)59-43(69)36(22-28(3)4)61-44(70)37(24-29-11-7-6-8-12-29)57-38(64)25-56-39(65)26-62(5)45(71)32(48)23-30-15-17-31(63)18-16-30/h6-8,11-12,15-18,27-28,32-37,63H,9-10,13-14,19-26,48H2,1-5H3,(H2,49,66)(H,56,65)(H,57,64)(H,58,67)(H,59,69)(H,60,68)(H,61,70)(H4,50,51,54)(H4,52,53,55)/t32-,33-,34-,35-,36-,37-/m0/s1 FCCVEVGXEFJWGD-DUGSHLAESA-N 50010533 2-{2-[2-(2-{2-[2-(2-{[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-methyl-amino}-acetylamino)-acetylamino]-3-phenyl-propionylamino}-4-methyl-pentanoylamino)-5-guanidino-pentanoylamino]-5-guanidino-pentanoylamino}-4-methyl-pentanoic acid amide::CHEMBL385736 Mu-type opioid receptor Cavia cutleri 897 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010533 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010533&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44307169 103923309 CHEMBL385736 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015552 CC(C)C[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O InChI=1S/C47H75N15O9/c1-26(2)21-35(39(49)65)61-43(69)34(14-10-20-55-47(52)53)59-42(68)33(13-9-19-54-46(50)51)60-44(70)36(22-27(3)4)62-45(71)37(24-29-11-7-6-8-12-29)58-38(64)25-56-40(66)28(5)57-41(67)32(48)23-30-15-17-31(63)18-16-30/h6-8,11-12,15-18,26-28,32-37,63H,9-10,13-14,19-25,48H2,1-5H3,(H2,49,65)(H,56,66)(H,57,67)(H,58,64)(H,59,68)(H,60,70)(H,61,69)(H,62,71)(H4,50,51,54)(H4,52,53,55)/t28-,32-,33-,34-,35-,36-,37-/m0/s1 AYOSEAIEHXRVMB-KHLMYIKTSA-N 50010531 2-[2-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-5-guanidino-pentanoylamino)-5-guanidino-pentanoylamino]-4-methyl-pentanoic acid amide::CHEMBL412324 Mu-type opioid receptor Cavia cutleri 6.9 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010531 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010531&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44307167 103923307 CHEMBL412324 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015553 CN[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)NNC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(N)=O InChI=1S/C46H74N16O9/c1-26(2)21-33(38(47)65)58-41(68)32(14-10-20-54-45(50)51)56-40(67)31(13-9-19-53-44(48)49)57-42(69)35(22-27(3)4)59-43(70)36(24-28-11-7-6-8-12-28)60-46(71)62-61-37(64)25-55-39(66)34(52-5)23-29-15-17-30(63)18-16-29/h6-8,11-12,15-18,26-27,31-36,52,63H,9-10,13-14,19-25H2,1-5H3,(H2,47,65)(H,55,66)(H,56,67)(H,57,69)(H,58,68)(H,59,70)(H,61,64)(H4,48,49,53)(H4,50,51,54)(H2,60,62,71)/t31-,32-,33-,34-,35-,36-/m0/s1 RQXXCFZBIBPJMF-NGTAMTFRSA-N 50010539 CHEMBL406034::MeTyr-Gly-Azgly-Phe-Leu-Arg-Arg-D-Leu-NH2 Mu-type opioid receptor Cavia cutleri 19 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010539 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010539&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44307213 103923315 CHEMBL406034 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015560 CN[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(N)=O InChI=1S/C48H77N15O9/c1-27(2)22-35(40(49)66)61-44(70)34(15-11-21-56-48(52)53)59-43(69)33(14-10-20-55-47(50)51)60-45(71)37(23-28(3)4)63-46(72)38(25-30-12-8-7-9-13-30)62-41(67)29(5)58-39(65)26-57-42(68)36(54-6)24-31-16-18-32(64)19-17-31/h7-9,12-13,16-19,27-29,33-38,54,64H,10-11,14-15,20-26H2,1-6H3,(H2,49,66)(H,57,68)(H,58,65)(H,59,69)(H,60,71)(H,61,70)(H,62,67)(H,63,72)(H4,50,51,55)(H4,52,53,56)/t29-,33+,34+,35+,36+,37+,38+/m1/s1 STAOFAVYNCLOCN-DEYFMMSJSA-N 50010541 2-[5-Guanidino-2-(5-guanidino-2-{2-[2-(2-{2-[3-(4-hydroxy-phenyl)-2-methylamino-propionylamino]-acetylamino}-propionylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-pentanoylamino)-pentanoylamino]-4-methyl-pentanoic acid amide::CHEMBL217597 Mu-type opioid receptor Cavia cutleri 13 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010541 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010541&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44307170 103923317 CHEMBL217597 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015561 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O InChI=1S/C46H73N15O9/c1-5-27(4)38(39(48)65)61-42(68)33(14-10-20-54-46(51)52)58-41(67)32(13-9-19-53-45(49)50)59-43(69)34(21-26(2)3)60-44(70)35(23-28-11-7-6-8-12-28)57-37(64)25-55-36(63)24-56-40(66)31(47)22-29-15-17-30(62)18-16-29/h6-8,11-12,15-18,26-27,31-35,38,62H,5,9-10,13-14,19-25,47H2,1-4H3,(H2,48,65)(H,55,63)(H,56,66)(H,57,64)(H,58,67)(H,59,69)(H,60,70)(H,61,68)(H4,49,50,53)(H4,51,52,54)/t27-,31-,32-,33-,34-,35+,38-/m0/s1 ALYDWGRDFMLDRH-VORHEVMJSA-N 50010538 2-[2-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-5-guanidino-pentanoylamino)-5-guanidino-pentanoylamino]-3-methyl-pentanoic acid amide::CHEMBL437242 Mu-type opioid receptor Cavia cutleri 0.200000 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010538 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010538&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44307234 103923314 CHEMBL437242 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015566 CN[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)NCC(=O)N[C@H](Cc1ccccc1)C(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(N)=O InChI=1S/C48H77N15O9/c1-28(2)22-35(41(49)67)62-44(70)33(14-10-20-55-47(50)51)60-43(69)34(15-11-21-56-48(52)53)61-45(71)38(23-29(3)4)63(6)46(72)37(25-30-12-8-7-9-13-30)59-40(66)27-57-39(65)26-58-42(68)36(54-5)24-31-16-18-32(64)19-17-31/h7-9,12-13,16-19,28-29,33-38,54,64H,10-11,14-15,20-27H2,1-6H3,(H2,49,67)(H,57,65)(H,58,68)(H,59,66)(H,60,69)(H,61,71)(H,62,70)(H4,50,51,55)(H4,52,53,56)/t33-,34-,35-,36-,37+,38-/m0/s1 WZOGXQPCETVHOV-WRQFUQGOSA-N 50010547 2-{5-Guanidino-2-[5-guanidino-2-(2-{[2-(2-{2-[3-(4-hydroxy-phenyl)-2-methylamino-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionyl]-methyl-amino}-4-methyl-pentanoylamino)-pentanoylamino]-pentanoylamino}-4-methyl-pentanoic acid amide::CHEMBL216351 Mu-type opioid receptor Cavia cutleri 12 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010547 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010547&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44307038 103923323 CHEMBL216351 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015567 CN[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)NCC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(N)=O InChI=1S/C44H69N15O9/c1-25(2)20-32(37(45)63)59-41(67)31(13-9-19-52-44(48)49)58-40(66)30(12-8-18-51-43(46)47)57-38(64)26(3)55-42(68)34(22-27-10-6-5-7-11-27)56-36(62)24-53-35(61)23-54-39(65)33(50-4)21-28-14-16-29(60)17-15-28/h5-7,10-11,14-17,25-26,30-34,50,60H,8-9,12-13,18-24H2,1-4H3,(H2,45,63)(H,53,61)(H,54,65)(H,55,68)(H,56,62)(H,57,64)(H,58,66)(H,59,67)(H4,46,47,51)(H4,48,49,52)/t26-,30+,31+,32+,33+,34-/m1/s1 FEHIRDAILRCTKI-FJDAGKCQSA-N 50010530 2-[5-Guanidino-2-(5-guanidino-2-{2-[2-(2-{2-[3-(4-hydroxy-phenyl)-2-methylamino-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-propionylamino}-pentanoylamino)-pentanoylamino]-4-methyl-pentanoic acid amide::CHEMBL306016 Mu-type opioid receptor Cavia cutleri 6000 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010530 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010530&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44307037 103923306 CHEMBL306016 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015572 CN[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)NCC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(N)=O InChI=1S/C47H75N15O9/c1-27(2)21-34(40(48)66)61-43(69)33(14-10-20-55-47(51)52)59-42(68)32(13-9-19-54-46(49)50)60-44(70)36(22-28(3)4)62-45(71)37(24-29-11-7-6-8-12-29)58-39(65)26-56-38(64)25-57-41(67)35(53-5)23-30-15-17-31(63)18-16-30/h6-8,11-12,15-18,27-28,32-37,53,63H,9-10,13-14,19-26H2,1-5H3,(H2,48,66)(H,56,64)(H,57,67)(H,58,65)(H,59,68)(H,60,70)(H,61,69)(H,62,71)(H4,49,50,54)(H4,51,52,55)/t32-,33-,34-,35-,36-,37+/m0/s1 OBZTVKAUYYDOFM-OZBJQVERSA-N 50010536 2-[5-Guanidino-2-(5-guanidino-2-{2-[2-(2-{2-[3-(4-hydroxy-phenyl)-2-methylamino-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-pentanoylamino)-pentanoylamino]-4-methyl-pentanoic acid amide::CHEMBL263031 Mu-type opioid receptor Cavia cutleri 2.8 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010536 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010536&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44306645 103923312 CHEMBL263031 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015575 CN[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(N)=O InChI=1S/C47H75N15O9/c1-27(2)21-34(40(48)66)61-43(69)33(14-10-20-55-47(51)52)59-42(68)32(13-9-19-54-46(49)50)60-44(70)36(22-28(3)4)62-45(71)37(24-29-11-7-6-8-12-29)58-39(65)26-56-38(64)25-57-41(67)35(53-5)23-30-15-17-31(63)18-16-30/h6-8,11-12,15-18,27-28,32-37,53,63H,9-10,13-14,19-26H2,1-5H3,(H2,48,66)(H,56,64)(H,57,67)(H,58,65)(H,59,68)(H,60,70)(H,61,69)(H,62,71)(H4,49,50,54)(H4,51,52,55)/t32-,33-,34-,35-,36-,37-/m0/s1 OBZTVKAUYYDOFM-DUGSHLAESA-N 50010529 2-[5-Guanidino-2-(5-guanidino-2-{2-[2-(2-{2-[3-(4-hydroxy-phenyl)-2-methylamino-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-pentanoylamino)-pentanoylamino]-4-methyl-pentanoic acid amide::CHEMBL407693 Mu-type opioid receptor Cavia cutleri >3000 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010529 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010529&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44307039 103923305 CHEMBL407693 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015577 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 72 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015580 CN[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)NCC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(N)=O InChI=1S/C47H75N15O9/c1-27(2)21-34(40(48)66)61-43(69)33(14-10-20-55-47(51)52)59-42(68)32(13-9-19-54-46(49)50)60-44(70)36(22-28(3)4)62-45(71)37(24-29-11-7-6-8-12-29)58-39(65)26-56-38(64)25-57-41(67)35(53-5)23-30-15-17-31(63)18-16-30/h6-8,11-12,15-18,27-28,32-37,53,63H,9-10,13-14,19-26H2,1-5H3,(H2,48,66)(H,56,64)(H,57,67)(H,58,65)(H,59,68)(H,60,70)(H,61,69)(H,62,71)(H4,49,50,54)(H4,51,52,55)/t32-,33-,34-,35-,36+,37+/m0/s1 OBZTVKAUYYDOFM-WOKAEJKNSA-N 50010549 2-[5-Guanidino-2-(5-guanidino-2-{2-[2-(2-{2-[3-(4-hydroxy-phenyl)-2-methylamino-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-pentanoylamino)-pentanoylamino]-4-methyl-pentanoic acid amide::CHEMBL274875 Mu-type opioid receptor Cavia cutleri 82 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010549 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010549&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44306936 103923325 CHEMBL274875 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50017695 C[C@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCN)N(C(=O)[C@@H](N)Cc2ccc(O)cc2)C1=O InChI=1S/C25H31N5O5/c1-15-24(34)30(25(35)19(27)13-17-7-9-18(31)10-8-17)21(11-12-26)23(33)29-20(22(32)28-15)14-16-5-3-2-4-6-16/h2-10,15,19-21,31H,11-14,26-27H2,1H3,(H,28,32)(H,29,33)/t15-,19+,20+,21+/m1/s1 SCJYSRHBQJDUEF-DVMWJLJYSA-N 50108489 (3R,6S,9S)-9-(2-Amino-ethyl)-1-[(S)-2-amino-3-(4-hydroxy-phenyl)-propionyl]-6-benzyl-3-methyl-[1,4,7]triazonane-2,5,8-trione::CHEMBL302277 Mu-type opioid receptor Cavia cutleri 3.5 ChEMBL 10.1016/s0960-894x(01)00706-5 10.7270/Q2W096FD 11755357 Burden, JE; Davis, P; Porreca, F; Spatola, AF University of Louisville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108489 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108489&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44308446 104003708 CHEMBL302277 ZINC26266605 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50017696 NCCCC[C@@H]1N(C(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)[C@@H](CC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC1=O InChI=1S/C28H35N5O7/c29-13-5-4-8-23-26(38)31-21(15-17-6-2-1-3-7-17)25(37)32-22(16-24(35)36)28(40)33(23)27(39)20(30)14-18-9-11-19(34)12-10-18/h1-3,6-7,9-12,20-23,34H,4-5,8,13-16,29-30H2,(H,31,38)(H,32,37)(H,35,36)/t20-,21-,22+,23-/m0/s1 YGOHPYBYDIYEPZ-GPJHCHHRSA-N 50108488 CHEMBL66706::{(2R,5S,8S)-5-(4-Amino-butyl)-4-[(S)-2-amino-3-(4-hydroxy-phenyl)-propionyl]-8-benzyl-3,6,9-trioxo-[1,4,7]triazonan-2-yl}-acetic acid Mu-type opioid receptor Cavia cutleri 79 ChEMBL 10.1016/s0960-894x(01)00706-5 10.7270/Q2W096FD 11755357 Burden, JE; Davis, P; Porreca, F; Spatola, AF University of Louisville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108488 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108488&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44308060 104003707 CHEMBL66706 ZINC26258060 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50017697 C[C@H]1NC[C@H](Cc2ccccc2)NC(=O)[C@H](CCN)N(C(=O)[C@@H](N)Cc2ccc(O)cc2)C1=O InChI=1S/C25H33N5O4/c1-16-24(33)30(25(34)21(27)14-18-7-9-20(31)10-8-18)22(11-12-26)23(32)29-19(15-28-16)13-17-5-3-2-4-6-17/h2-10,16,19,21-22,28,31H,11-15,26-27H2,1H3,(H,29,32)/t16-,19+,21+,22+/m1/s1 VRJXDRVYIPBHFP-XEHJXZTKSA-N 50108491 (3S,6R,9S)-3-(2-Amino-ethyl)-4-[(S)-2-amino-3-(4-hydroxy-phenyl)-propionyl]-9-benzyl-6-methyl-[1,4,7]triazonane-2,5-dione::CHEMBL65894 Mu-type opioid receptor Cavia cutleri 21 ChEMBL 10.1016/s0960-894x(01)00706-5 10.7270/Q2W096FD 11755357 Burden, JE; Davis, P; Porreca, F; Spatola, AF University of Louisville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108491 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108491&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44308119 104003710 CHEMBL65894 ZINC26261235 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50017698 CC(C)C[C@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCCN)N(C(=O)[C@@H](N)Cc2ccc(O)cc2)C1=O InChI=1S/C30H41N5O5/c1-19(2)16-25-30(40)35(29(39)23(32)17-21-11-13-22(36)14-12-21)26(10-6-7-15-31)28(38)33-24(27(37)34-25)18-20-8-4-3-5-9-20/h3-5,8-9,11-14,19,23-26,36H,6-7,10,15-18,31-32H2,1-2H3,(H,33,38)(H,34,37)/t23-,24-,25+,26-/m0/s1 SMADVSFCWKOSPV-SSUZURRFSA-N 50108486 (3R,6S,9S)-9-(4-Amino-butyl)-1-[(S)-2-amino-3-(4-hydroxy-phenyl)-propionyl]-6-benzyl-3-isobutyl-[1,4,7]triazonane-2,5,8-trione::CHEMBL307323 Mu-type opioid receptor Cavia cutleri 1.4 ChEMBL 10.1016/s0960-894x(01)00706-5 10.7270/Q2W096FD 11755357 Burden, JE; Davis, P; Porreca, F; Spatola, AF University of Louisville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108486 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108486&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44308061 104003705 CHEMBL307323 ZINC26258068 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50017699 CC(C)[C@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCCN)N(C(=O)[C@@H](N)Cc2ccc(O)cc2)C1=O InChI=1S/C29H39N5O5/c1-18(2)25-29(39)34(28(38)22(31)16-20-11-13-21(35)14-12-20)24(10-6-7-15-30)27(37)32-23(26(36)33-25)17-19-8-4-3-5-9-19/h3-5,8-9,11-14,18,22-25,35H,6-7,10,15-17,30-31H2,1-2H3,(H,32,37)(H,33,36)/t22-,23-,24-,25+/m0/s1 ATWURJJJKREKHL-OJJQZRKESA-N 50108487 (3R,6S,9S)-9-(4-Amino-butyl)-1-[(S)-2-amino-3-(4-hydroxy-phenyl)-propionyl]-6-benzyl-3-isopropyl-[1,4,7]triazonane-2,5,8-trione::CHEMBL307133 Mu-type opioid receptor Cavia cutleri 0.200000 ChEMBL 10.1016/s0960-894x(01)00706-5 10.7270/Q2W096FD 11755357 Burden, JE; Davis, P; Porreca, F; Spatola, AF University of Louisville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108487 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108487&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44308087 104003706 CHEMBL307133 ZINC26270220 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50017700 C[C@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCCN)N(C(=O)[C@@H](N)Cc2ccc(O)cc2)C1=O InChI=1S/C27H35N5O5/c1-17-26(36)32(27(37)21(29)15-19-10-12-20(33)13-11-19)23(9-5-6-14-28)25(35)31-22(24(34)30-17)16-18-7-3-2-4-8-18/h2-4,7-8,10-13,17,21-23,33H,5-6,9,14-16,28-29H2,1H3,(H,30,34)(H,31,35)/t17-,21+,22+,23+/m1/s1 SOLGEXWMHBGXCY-SZOBAZRNSA-N 50108490 (3R,6S,9S)-9-(4-Amino-butyl)-1-[(S)-2-amino-3-(4-hydroxy-phenyl)-propionyl]-6-benzyl-3-methyl-[1,4,7]triazonane-2,5,8-trione::CHEMBL66009 Mu-type opioid receptor Cavia cutleri 0.110000 ChEMBL 10.1016/s0960-894x(01)00706-5 10.7270/Q2W096FD 11755357 Burden, JE; Davis, P; Porreca, F; Spatola, AF University of Louisville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108490 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108490&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44308607 104003709 CHEMBL66009 ZINC26262012 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50017701 CC[C@@H](C)[C@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCCN)N(C(=O)[C@@H](N)Cc2ccc(O)cc2)C1=O InChI=1S/C30H41N5O5/c1-3-19(2)26-30(40)35(29(39)23(32)17-21-12-14-22(36)15-13-21)25(11-7-8-16-31)28(38)33-24(27(37)34-26)18-20-9-5-4-6-10-20/h4-6,9-10,12-15,19,23-26,36H,3,7-8,11,16-18,31-32H2,1-2H3,(H,33,38)(H,34,37)/t19-,23+,24+,25+,26-/m1/s1 RUGISWDTRCEARY-MJGRMWDMSA-N 50366797 CHEMBL1790503 Mu-type opioid receptor Cavia cutleri 1.1 ChEMBL 10.1016/s0960-894x(01)00706-5 10.7270/Q2W096FD 11755357 Burden, JE; Davis, P; Porreca, F; Spatola, AF University of Louisville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366797&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 56675769 160845899 CHEMBL1790503 ZINC26262540 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015835 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC1=O)C(N)=O InChI=1S/C69H112N24O14S2/c1-38(2)30-48(90-63(104)50(33-40-14-6-5-7-15-40)84-55(96)35-82-54(95)34-83-57(98)43(71)32-41-21-23-42(94)24-22-41)61(102)86-45(17-10-26-79-67(73)74)58(99)85-46(18-11-27-80-68(75)76)60(101)92-52-37-109-108-36-51(56(72)97)91-62(103)49(31-39(3)4)89-59(100)44(16-8-9-25-70)87-65(106)53-20-13-29-93(53)66(107)47(88-64(52)105)19-12-28-81-69(77)78/h5-7,14-15,21-24,38-39,43-53,94H,8-13,16-20,25-37,70-71H2,1-4H3,(H2,72,97)(H,82,95)(H,83,98)(H,84,96)(H,85,99)(H,86,102)(H,87,106)(H,88,105)(H,89,100)(H,90,104)(H,91,103)(H,92,101)(H4,73,74,79)(H4,75,76,80)(H4,77,78,81)/t43-,44-,45-,46-,47-,48-,49-,50-,51-,52-,53-/m0/s1 CIDXGGKDEWZDBR-ZOOWYRFPSA-N 50010703 CHEMBL443068::H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Cys-Arg-Pro-Lys-Leu-Cys-NH2 Mu-type opioid receptor Cavia cutleri 0.986000 ChEMBL 10.1021/jm00169a007 10.7270/Q2FB51XH 1972964 Kawasaki, AM; Knapp, RJ; Kramer, TH; Wire, WS; Vasquez, OS; Yamamura, HI; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010703 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010703&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25087514 103923449 CHEMBL443068 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015836 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(O)=O InChI=1S/C99H155N31O23/c1-7-55(6)81(129-86(142)66(28-18-40-112-98(107)108)118-83(139)65(27-17-39-111-97(105)106)120-88(144)70(44-54(4)5)125-89(145)71(46-56-21-9-8-10-22-56)117-79(135)52-115-78(134)51-116-82(138)61(102)45-57-31-33-59(131)34-32-57)94(150)122-67(29-19-41-113-99(109)110)95(151)130-42-20-30-75(130)93(149)121-64(26-14-16-38-101)85(141)124-69(43-53(2)3)87(143)119-63(25-13-15-37-100)84(140)126-72(47-58-50-114-62-24-12-11-23-60(58)62)90(146)128-74(49-80(136)137)92(148)127-73(48-77(104)133)91(147)123-68(96(152)153)35-36-76(103)132/h8-12,21-24,31-34,50,53-55,61,63-75,81,114,131H,7,13-20,25-30,35-49,51-52,100-102H2,1-6H3,(H2,103,132)(H2,104,133)(H,115,134)(H,116,138)(H,117,135)(H,118,139)(H,119,143)(H,120,144)(H,121,149)(H,122,150)(H,123,147)(H,124,141)(H,125,145)(H,126,140)(H,127,148)(H,128,146)(H,129,142)(H,136,137)(H,152,153)(H4,105,106,111)(H4,107,108,112)(H4,109,110,113)/t55-,61-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,81-/m0/s1 JMNJYGMAUMANNW-FIXZTSJVSA-N 50010702 CHEMBL411557::DYNORPHIN(1-17)-OH::Dynorphin A (1-17)::H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln-OH::Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln::dynorphin A Mu-type opioid receptor Cavia cutleri 5 ChEMBL 10.1021/jm00169a007 10.7270/Q2FB51XH 1972964 Kawasaki, AM; Knapp, RJ; Kramer, TH; Wire, WS; Vasquez, OS; Yamamura, HI; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010702&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 91928823 103923448 CHEMBL411557 C02716 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015837 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]1CSSC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC1=O)C(N)=O InChI=1S/C69H112N24O14S2/c1-38(2)30-48(90-63(104)50(33-40-14-6-5-7-15-40)84-55(96)35-82-54(95)34-83-57(98)43(71)32-41-21-23-42(94)24-22-41)61(102)86-45(17-10-26-79-67(73)74)58(99)85-46(18-11-27-80-68(75)76)60(101)92-52-37-109-108-36-51(56(72)97)91-62(103)49(31-39(3)4)89-59(100)44(16-8-9-25-70)87-65(106)53-20-13-29-93(53)66(107)47(88-64(52)105)19-12-28-81-69(77)78/h5-7,14-15,21-24,38-39,43-53,94H,8-13,16-20,25-37,70-71H2,1-4H3,(H2,72,97)(H,82,95)(H,83,98)(H,84,96)(H,85,99)(H,86,102)(H,87,106)(H,88,105)(H,89,100)(H,90,104)(H,91,103)(H,92,101)(H4,73,74,79)(H4,75,76,80)(H4,77,78,81)/t43-,44-,45-,46-,47-,48-,49-,50-,51-,52+,53-/m0/s1 CIDXGGKDEWZDBR-KJSOZXTISA-N 50010706 CHEMBL384250::H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-D-Cys-Arg-Pro-Lys-Leu-Cys-NH2 Mu-type opioid receptor Cavia cutleri 10 ChEMBL 10.1021/jm00169a007 10.7270/Q2FB51XH 1972964 Kawasaki, AM; Knapp, RJ; Kramer, TH; Wire, WS; Vasquez, OS; Yamamura, HI; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010706 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010706&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25087515 103923452 CHEMBL384250 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015838 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]1CSSC[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC1=O)C(N)=O InChI=1S/C69H112N24O14S2/c1-38(2)30-48(90-63(104)50(33-40-14-6-5-7-15-40)84-55(96)35-82-54(95)34-83-57(98)43(71)32-41-21-23-42(94)24-22-41)61(102)86-45(17-10-26-79-67(73)74)58(99)85-46(18-11-27-80-68(75)76)60(101)92-52-37-109-108-36-51(56(72)97)91-62(103)49(31-39(3)4)89-59(100)44(16-8-9-25-70)87-65(106)53-20-13-29-93(53)66(107)47(88-64(52)105)19-12-28-81-69(77)78/h5-7,14-15,21-24,38-39,43-53,94H,8-13,16-20,25-37,70-71H2,1-4H3,(H2,72,97)(H,82,95)(H,83,98)(H,84,96)(H,85,99)(H,86,102)(H,87,106)(H,88,105)(H,89,100)(H,90,104)(H,91,103)(H,92,101)(H4,73,74,79)(H4,75,76,80)(H4,77,78,81)/t43-,44-,45-,46-,47-,48-,49-,50-,51+,52+,53-/m0/s1 CIDXGGKDEWZDBR-NGZBXPRISA-N 50010701 CHEMBL410616::H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-D-Cys-Arg-Pro-Lys-Leu-D-Cys-NH2 Mu-type opioid receptor Cavia cutleri 0.362000 ChEMBL 10.1021/jm00169a007 10.7270/Q2FB51XH 1972964 Kawasaki, AM; Knapp, RJ; Kramer, TH; Wire, WS; Vasquez, OS; Yamamura, HI; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010701 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010701&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25087516 103923447 CHEMBL410616 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015843 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C28H37N5O7/c1-17(2)12-23(28(39)40)33-27(38)22(14-18-6-4-3-5-7-18)32-25(36)16-30-24(35)15-31-26(37)21(29)13-19-8-10-20(34)11-9-19/h3-11,17,21-23,34H,12-16,29H2,1-2H3,(H,30,35)(H,31,37)(H,32,36)(H,33,38)(H,39,40)/t21-,22-,23-/m0/s1 URLZCHNOLZSCCA-VABKMULXSA-N 50001465 (S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::([Leu]-enkephalin)2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::(enkephalin)2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-1-oxo-3-phenyl-propylamino]-4-methyl-pentanoic acid::2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::2-[1-[1-amino-2-(4-hydroxyphenyl)-(1S)-ethylcarboxamidomethylcarboxamidomethylcarboxamido]-2-phenyl-(1S)-ethylcarboxamido]-4-methyl-(2S)-pentanoic acid::2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid(Enkephalin)::2-{1-[1-amino-2-(4-hydroxyphenyl)ethylcarboxamidomethylcarboxamidomethylcarboxamido]-2-phenylethylcarboxamido}-4-methylpentanoic acid::CHEMBL8234::ENKEPHALIN::Leu-ENKEPHALIN::Leu5-Enkephalin::Tyr-Gly-Gly-Phe-Leu-OH Mu-type opioid receptor Cavia cutleri 103 ChEMBL 10.1016/s0960-894x(00)00665-x 10.7270/Q2571B8P 11212102 Sasaki, Y; Hirabuki, M; Ambo, A; Ouchi, H; Yamamoto, Y Tohoku Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001465&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 461776 103915930 CHEMBL8234 ZINC14952116 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015847 CC(C)C[C@H](NC(=O)[C@@H](Cc1c(C)cccc1C)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C30H41N5O7/c1-17(2)12-25(30(41)42)35-29(40)24(14-22-18(3)6-5-7-19(22)4)34-27(38)16-32-26(37)15-33-28(39)23(31)13-20-8-10-21(36)11-9-20/h5-11,17,23-25,36H,12-16,31H2,1-4H3,(H,32,37)(H,33,39)(H,34,38)(H,35,40)(H,41,42)/t23-,24+,25-/m0/s1 CFAAVEWLIQGTCN-GVAUOCQISA-N 50096720 (S)-2-[(R)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-(2,6-dimethyl-phenyl)-propionylamino]-4-methyl-pentanoic acid::CHEMBL109554 Mu-type opioid receptor Cavia cutleri 808 ChEMBL 10.1016/s0960-894x(00)00665-x 10.7270/Q2571B8P 11212102 Sasaki, Y; Hirabuki, M; Ambo, A; Ouchi, H; Yamamoto, Y Tohoku Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50096720 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50096720&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44340095 103994199 CHEMBL109554 ZINC26971503 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015855 CC(C)C[C@H](NC(=O)[C@H](Cc1c(C)cccc1C)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C30H41N5O7/c1-17(2)12-25(30(41)42)35-29(40)24(14-22-18(3)6-5-7-19(22)4)34-27(38)16-32-26(37)15-33-28(39)23(31)13-20-8-10-21(36)11-9-20/h5-11,17,23-25,36H,12-16,31H2,1-4H3,(H,32,37)(H,33,39)(H,34,38)(H,35,40)(H,41,42)/t23-,24-,25-/m0/s1 CFAAVEWLIQGTCN-SDHOMARFSA-N 50096717 (S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-(2,6-dimethyl-phenyl)-propionylamino]-4-methyl-pentanoic acid::CHEMBL112708 Mu-type opioid receptor Cavia cutleri >10 ChEMBL 10.1016/s0960-894x(00)00665-x 10.7270/Q2571B8P 11212102 Sasaki, Y; Hirabuki, M; Ambo, A; Ouchi, H; Yamamoto, Y Tohoku Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50096717 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50096717&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44340501 103994196 CHEMBL112708 ZINC26990816 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015856 CC(C)C[C@H](NC(=O)[C@@H](Cc1c(C)cccc1C)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(O)=O InChI=1S/C32H45N5O7/c1-17(2)10-27(32(43)44)37-31(42)26(14-24-18(3)8-7-9-19(24)4)36-29(40)16-34-28(39)15-35-30(41)25(33)13-23-20(5)11-22(38)12-21(23)6/h7-9,11-12,17,25-27,38H,10,13-16,33H2,1-6H3,(H,34,39)(H,35,41)(H,36,40)(H,37,42)(H,43,44)/t25-,26+,27-/m0/s1 OLHDSEHCXLLTLE-VJGNERBWSA-N 50096719 (S)-2-[(R)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-(2,6-dimethyl-phenyl)-propionylamino]-4-methyl-pentanoic acid::CHEMBL109327 Mu-type opioid receptor Cavia cutleri 2 ChEMBL 10.1016/s0960-894x(00)00665-x 10.7270/Q2571B8P 11212102 Sasaki, Y; Hirabuki, M; Ambo, A; Ouchi, H; Yamamoto, Y Tohoku Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50096719 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50096719&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10393974 103994198 CHEMBL109327 ZINC26973402 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015857 CC(C)C[C@H](NC(=O)[C@H](Cc1c(C)cccc1C)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(O)=O InChI=1S/C32H45N5O7/c1-17(2)10-27(32(43)44)37-31(42)26(14-24-18(3)8-7-9-19(24)4)36-29(40)16-34-28(39)15-35-30(41)25(33)13-23-20(5)11-22(38)12-21(23)6/h7-9,11-12,17,25-27,38H,10,13-16,33H2,1-6H3,(H,34,39)(H,35,41)(H,36,40)(H,37,42)(H,43,44)/t25-,26-,27-/m0/s1 OLHDSEHCXLLTLE-QKDODKLFSA-N 50096718 (S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-(2,6-dimethyl-phenyl)-propionylamino]-4-methyl-pentanoic acid::CHEMBL111028 Mu-type opioid receptor Cavia cutleri >10 ChEMBL 10.1016/s0960-894x(00)00665-x 10.7270/Q2571B8P 11212102 Sasaki, Y; Hirabuki, M; Ambo, A; Ouchi, H; Yamamoto, Y Tohoku Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50096718 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50096718&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44340096 103994197 CHEMBL111028 ZINC26960926 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015861 C[C@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC1=O)C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C54H83N21O12S2/c1-29-44(80)72-36(13-7-21-65-54(61)62)51(87)75-22-8-14-40(75)50(86)73-38(43(56)79)27-88-89-28-39(49(85)71-35(12-6-20-64-53(59)60)47(83)70-34(46(82)68-29)11-5-19-63-52(57)58)74-48(84)37(24-30-9-3-2-4-10-30)69-42(78)26-66-41(77)25-67-45(81)33(55)23-31-15-17-32(76)18-16-31/h2-4,9-10,15-18,29,33-40,76H,5-8,11-14,19-28,55H2,1H3,(H2,56,79)(H,66,77)(H,67,81)(H,68,82)(H,69,78)(H,70,83)(H,71,85)(H,72,80)(H,73,86)(H,74,84)(H4,57,58,63)(H4,59,60,64)(H4,61,62,65)/t29-,33+,34+,35+,36+,37+,38+,39+,40+/m1/s1 QXGFABTWRXRRJN-UUAWHVCESA-N 50010700 CHEMBL265824::H-Tyr-Gly-Gly-Phe-Cys-Arg-Arg-D-Ala-Arg-Pro-Cys-NH2 Mu-type opioid receptor Cavia cutleri 2.3 ChEMBL 10.1021/jm00169a007 10.7270/Q2FB51XH 1972964 Kawasaki, AM; Knapp, RJ; Kramer, TH; Wire, WS; Vasquez, OS; Yamamura, HI; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010700 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010700&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15160017 103923446 CHEMBL265824 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015863 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(O)=O InChI=1S/C30H41N5O7/c1-17(2)10-25(30(41)42)35-29(40)24(13-20-8-6-5-7-9-20)34-27(38)16-32-26(37)15-33-28(39)23(31)14-22-18(3)11-21(36)12-19(22)4/h5-9,11-12,17,23-25,36H,10,13-16,31H2,1-4H3,(H,32,37)(H,33,39)(H,34,38)(H,35,40)(H,41,42)/t23-,24-,25-/m0/s1 JVCXXLBLDDZMDG-SDHOMARFSA-N 50096716 CHEMBL100480::Enkephalin derivative Mu-type opioid receptor Cavia cutleri 0.550000 ChEMBL 10.1016/s0960-894x(00)00665-x 10.7270/Q2571B8P 11212102 Sasaki, Y; Hirabuki, M; Ambo, A; Ouchi, H; Yamamoto, Y Tohoku Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50096716 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50096716&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10579175 103994195 CHEMBL100480 ZINC26960915 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015865 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C63H104N22O12/c1-5-37(4)51(59(96)82-45(20-13-29-75-63(71)72)60(97)85-30-14-21-48(85)58(95)79-42(52(66)89)17-9-10-26-64)84-55(92)44(19-12-28-74-62(69)70)80-54(91)43(18-11-27-73-61(67)68)81-56(93)46(31-36(2)3)83-57(94)47(33-38-15-7-6-8-16-38)78-50(88)35-76-49(87)34-77-53(90)41(65)32-39-22-24-40(86)25-23-39/h6-8,15-16,22-25,36-37,41-48,51,86H,5,9-14,17-21,26-35,64-65H2,1-4H3,(H2,66,89)(H,76,87)(H,77,90)(H,78,88)(H,79,95)(H,80,91)(H,81,93)(H,82,96)(H,83,94)(H,84,92)(H4,67,68,73)(H4,69,70,74)(H4,71,72,75)/t37-,41-,42-,43-,44-,45-,46-,47-,48-,51-/m0/s1 OKJAOUBQLSWUNX-QFIUEGLPSA-N 50010704 CHEMBL216640::Dyn A(1-11)-NH2::Dynorphin A analogues::H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-NH2::HTyr-Gly-Gly-Phe-Leu-Arg-Arg-lle-Arg-Pro-LysNH2::Linear Dyn A-(1-11)NH2::Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-D-Lys-NH2::Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln-NH2 Mu-type opioid receptor Cavia cutleri 1.1 ChEMBL 10.1021/jm00169a007 10.7270/Q2FB51XH 1972964 Kawasaki, AM; Knapp, RJ; Kramer, TH; Wire, WS; Vasquez, OS; Yamamura, HI; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010704 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010704&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10677974 103923450 CHEMBL216640 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015866 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C75H127N25O14/c1-7-45(6)61(71(113)96-54(25-17-35-88-75(84)85)72(114)100-36-18-26-58(100)70(112)95-51(22-12-14-32-77)65(107)97-55(37-43(2)3)67(109)92-50(62(79)104)21-11-13-31-76)99-66(108)53(24-16-34-87-74(82)83)93-64(106)52(23-15-33-86-73(80)81)94-68(110)56(38-44(4)5)98-69(111)57(40-46-19-9-8-10-20-46)91-60(103)42-89-59(102)41-90-63(105)49(78)39-47-27-29-48(101)30-28-47/h8-10,19-20,27-30,43-45,49-58,61,101H,7,11-18,21-26,31-42,76-78H2,1-6H3,(H2,79,104)(H,89,102)(H,90,105)(H,91,103)(H,92,109)(H,93,106)(H,94,110)(H,95,112)(H,96,113)(H,97,107)(H,98,111)(H,99,108)(H4,80,81,86)(H4,82,83,87)(H4,84,85,88)/t45-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,61-/m0/s1 YJLKYUMEUZAMMP-IWIISZHXSA-N 50002184 CHEMBL415330::H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-NH2::Linear Dyn A-(1-13)NH2::Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys(Dynorphin A)::Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-NH2 Mu-type opioid receptor Cavia cutleri 1.3 ChEMBL 10.1021/jm00169a007 10.7270/Q2FB51XH 1972964 Kawasaki, AM; Knapp, RJ; Kramer, TH; Wire, WS; Vasquez, OS; Yamamura, HI; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002184 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002184&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25079852 103916490 CHEMBL415330 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015868 CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC1=O)C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C57H89N21O12S2/c1-3-31(2)45-53(89)74-38(15-9-23-68-57(64)65)54(90)78-24-10-16-42(78)52(88)75-40(46(59)82)29-91-92-30-41(51(87)73-36(13-7-21-66-55(60)61)48(84)72-37(49(85)77-45)14-8-22-67-56(62)63)76-50(86)39(26-32-11-5-4-6-12-32)71-44(81)28-69-43(80)27-70-47(83)35(58)25-33-17-19-34(79)20-18-33/h4-6,11-12,17-20,31,35-42,45,79H,3,7-10,13-16,21-30,58H2,1-2H3,(H2,59,82)(H,69,80)(H,70,83)(H,71,81)(H,72,84)(H,73,87)(H,74,89)(H,75,88)(H,76,86)(H,77,85)(H4,60,61,66)(H4,62,63,67)(H4,64,65,68)/t31-,35-,36-,37-,38-,39-,40-,41-,42-,45-/m0/s1 NTACCAONUHCRGG-QXKRRTFZSA-N 50010705 CHEMBL385759::H-Tyr-Gly-Gly-Phe-Cys-Arg-Arg-Ile-Arg-Pro-Cys-NH2 Mu-type opioid receptor Cavia cutleri 0.027000 ChEMBL 10.1021/jm00169a007 10.7270/Q2FB51XH 1972964 Kawasaki, AM; Knapp, RJ; Kramer, TH; Wire, WS; Vasquez, OS; Yamamura, HI; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010705 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010705&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10102939 103923451 CHEMBL385759 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50014835 Cn1c2[C@@H]3Oc4c5c(CC6N(CC7CC7)CC[C@@]35[C@@]6(O)Cc2c2C[C@@]3(O)C5Cc6ccc(O)c7O[C@@H](c12)[C@]3(CCN5CC1CC1)c67)ccc4O InChI=1S/C41H45N3O6/c1-42-32-24(16-40(47)28-14-22-6-8-26(45)34-30(22)38(40,36(32)49-34)10-12-43(28)18-20-2-3-20)25-17-41(48)29-15-23-7-9-27(46)35-31(23)39(41,37(50-35)33(25)42)11-13-44(29)19-21-4-5-21/h6-9,20-21,28-29,36-37,45-48H,2-5,10-19H2,1H3/t28?,29?,36-,37-,38-,39-,40+,41+/m0/s1 DKIVQMBUHVYDFC-NCMVRAGLSA-N 50009129 binaltorphimine(BNI) Mu-type opioid receptor Cavia cutleri 18 ChEMBL 10.1021/jm00108a008 10.7270/Q2C53MF5 1849995 Portoghese, PS; Garzon-Aburbeh, A; Nagase, H; Lin, CE; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009129&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44459905 103922186 ZINC27899504 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50020144 C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)N(C)C=O InChI=1S/C20H28N2O/c1-14-19-10-16-6-7-17(21(3)13-23)11-18(16)20(14,2)8-9-22(19)12-15-4-5-15/h6-7,11,13-15,19H,4-5,8-10,12H2,1-3H3/t14-,19?,20-/m0/s1 ZGFSHBJYIASPNJ-JUJMCKSGSA-N 50128412 CHEMBL293485::N-((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-N-methyl-formamide Mu-type opioid receptor Cavia cutleri 550 ChEMBL 10.1016/s0960-894x(03)00295-6 10.7270/Q2FB529V 12749896 Wentland, MP; Sun, X; Ye, Y; Lou, R; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128412 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128412&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300212 104020177 CHEMBL293485 ZINC29556306 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50020146 C[C@H]1C2Cc3ccc(NC=O)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C19H26N2O/c1-13-18-9-15-5-6-16(20-12-22)10-17(15)19(13,2)7-8-21(18)11-14-3-4-14/h5-6,10,12-14,18H,3-4,7-9,11H2,1-2H3,(H,20,22)/t13-,18?,19-/m0/s1 GRERSJXDCJKLDU-IMWIMMFESA-N 50128407 CHEMBL56246::N-((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-formamide Mu-type opioid receptor Cavia cutleri 1.9 ChEMBL 10.1016/s0960-894x(03)00295-6 10.7270/Q2FB529V 12749896 Wentland, MP; Sun, X; Ye, Y; Lou, R; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128407 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128407&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300216 104020172 CHEMBL56246 C06049 ZINC13490117 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50020147 CC[C@]12CCN(CC3CC3)C([C@@H]1C)C(=O)c1ccc(cc21)C(N)=O InChI=1S/C20H26N2O2/c1-3-20-8-9-22(11-13-4-5-13)17(12(20)2)18(23)15-7-6-14(19(21)24)10-16(15)20/h6-7,10,12-13,17H,3-5,8-9,11H2,1-2H3,(H2,21,24)/t12-,17?,20-/m0/s1 NBEPKKBOGWVFFT-HQWCKNPASA-N 50097586 (6S,11R)-3-Cyclopropylmethyl-6-ethyl-11-methyl-1-oxo-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid amide::3-cyclopropylmethyl-6-ethyl-11-methyl-1-oxo-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid amide::CHEMBL60869 Mu-type opioid receptor Cavia cutleri 1.2 ChEMBL 10.1016/s0960-894x(03)00295-6 10.7270/Q2FB529V 12749896 Wentland, MP; Sun, X; Ye, Y; Lou, R; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097586 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097586&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300146 103994794 CHEMBL60869 ZINC29563889 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50020152 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1 DQCKKXVULJGBQN-XFWGSAIBSA-N 60212 (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::MLS000069607::NALTREXONE HYDROCHLORIDE::SMR000058767::US10988481, Compound NTX::US9107954, naltrexone::cid_5485201 Mu-type opioid receptor Cavia cutleri 0.170000 ChEMBL 10.1016/s0960-894x(03)00295-6 10.7270/Q2FB529V 12749896 Wentland, MP; Sun, X; Ye, Y; Lou, R; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60212&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5360515 252639834 DB00704 C07253 ZINC00001773 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50020163 C[C@@H]1C2Cc3ccc(NC=O)cc3[C@]1(C)CCN2CC1CC1 InChI=1S/C19H26N2O/c1-13-18-9-15-5-6-16(20-12-22)10-17(15)19(13,2)7-8-21(18)11-14-3-4-14/h5-6,10,12-14,18H,3-4,7-9,11H2,1-2H3,(H,20,22)/t13-,18?,19-/m1/s1 GRERSJXDCJKLDU-MALVVIPZSA-N 50128406 (1S,9S,13S)-10-(cyclopropylmethyl)-1,13-dimethyl-10-azatricyclo[7.3.1.0~2,7~]trideca-2,4,6-trien-4-ylformamide::CHEMBL299027 Mu-type opioid receptor Cavia cutleri 2300 ChEMBL 10.1016/s0960-894x(03)00295-6 10.7270/Q2FB529V 12749896 Wentland, MP; Sun, X; Ye, Y; Lou, R; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128406 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128406&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300227 104020171 CHEMBL299027 C06049 ZINC29559744 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50020167 O[C@]12CCC(=O)[C@@H]3Oc4c5c(C[C@H]1N(CC1CC1)CC[C@@]235)ccc4NC=O InChI=1S/C21H24N2O4/c24-11-22-14-4-3-13-9-16-21(26)6-5-15(25)19-20(21,17(13)18(14)27-19)7-8-23(16)10-12-1-2-12/h3-4,11-12,16,19,26H,1-2,5-10H2,(H,22,24)/t16-,19+,20+,21-/m1/s1 OWJSYUVLLIVNEM-MBPVOVBZSA-N 50128413 CHEMBL298590::N-[4-cyclopropylmethyl-17-hydroxy-14-oxo-(1S,5R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-10-yl]methanamide Mu-type opioid receptor Cavia cutleri 8.3 ChEMBL 10.1016/s0960-894x(03)00295-6 10.7270/Q2FB529V 12749896 Wentland, MP; Sun, X; Ye, Y; Lou, R; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128413 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128413&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300188 104020178 CHEMBL298590 C06049 ZINC13490124 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50020168 CC1[C@H]2Cc3ccc(NC=O)cc3[C@]1(C)CCN2CC1CC1 InChI=1S/C19H26N2O/c1-13-18-9-15-5-6-16(20-12-22)10-17(15)19(13,2)7-8-21(18)11-14-3-4-14/h5-6,10,12-14,18H,3-4,7-9,11H2,1-2H3,(H,20,22)/t13?,18-,19-/m1/s1 GRERSJXDCJKLDU-GFWLXOEUSA-N 50128408 (1R,9R,13R)-10-(cyclopropylmethyl)-1,13-dimethyl-10-azatricyclo[7.3.1.0~2,7~]trideca-2,4,6-trien-4-ylformamide::CHEMBL57628 Mu-type opioid receptor Cavia cutleri 1.1 ChEMBL 10.1016/s0960-894x(03)00295-6 10.7270/Q2FB529V 12749896 Wentland, MP; Sun, X; Ye, Y; Lou, R; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128408 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128408&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 23519701 104020173 CHEMBL57628 C06049 ZINC13490118 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50020171 Nc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C20H24N2O3/c21-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-22(15)10-11-1-2-11/h3-4,11,15,18,24H,1-2,5-10,21H2/t15-,18+,19+,20-/m1/s1 GSRVQMUJFNWZGO-XFWGSAIBSA-N 50128410 10-amino-4-cyclopropylmethyl-17-hydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::CHEMBL59314 Mu-type opioid receptor Cavia cutleri 5.6 ChEMBL 10.1016/s0960-894x(03)00295-6 10.7270/Q2FB529V 12749896 Wentland, MP; Sun, X; Ye, Y; Lou, R; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128410 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128410&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299842 104020175 CHEMBL59314 ZINC13490126 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50020172 NC(=O)c1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C21H24N2O4/c22-19(25)13-4-3-12-9-15-21(26)6-5-14(24)18-20(21,16(12)17(13)27-18)7-8-23(15)10-11-1-2-11/h3-4,11,15,18,26H,1-2,5-10H2,(H2,22,25)/t15-,18+,20+,21-/m1/s1 QAICPHMNUHNDMC-WUHBCXKYSA-N 50128411 3-desoxy-3-carboxamidonaltrexone::4-cyclopropylmethyl-17-hydroxy-14-oxo-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-triene-10-carboxamide::CHEMBL56695 Mu-type opioid receptor Cavia cutleri 1.9 ChEMBL 10.1016/s0960-894x(03)00295-6 10.7270/Q2FB529V 12749896 Wentland, MP; Sun, X; Ye, Y; Lou, R; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128411 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128411&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10021946 104020176 CHEMBL56695 ZINC13490125 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50020174 C[C@H]1C2Cc3ccc(NC(C)=O)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C20H28N2O/c1-13-19-10-16-6-7-17(21-14(2)23)11-18(16)20(13,3)8-9-22(19)12-15-4-5-15/h6-7,11,13,15,19H,4-5,8-10,12H2,1-3H3,(H,21,23)/t13-,19?,20-/m0/s1 DZCRLOVBBXWFEC-RIHNOLBDSA-N 50128404 CHEMBL56357::N-((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-acetamide Mu-type opioid receptor Cavia cutleri 240 ChEMBL 10.1016/s0960-894x(03)00295-6 10.7270/Q2FB529V 12749896 Wentland, MP; Sun, X; Ye, Y; Lou, R; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128404 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128404&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299840 104020169 CHEMBL56357 ZINC29556079 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50020175 C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)C(=O)Nc1ccccc1 InChI=1S/C25H30N2O/c1-17-23-15-19-10-11-20(24(28)26-21-6-4-3-5-7-21)14-22(19)25(17,2)12-13-27(23)16-18-8-9-18/h3-7,10-11,14,17-18,23H,8-9,12-13,15-16H2,1-2H3,(H,26,28)/t17-,23?,25-/m0/s1 OVRRAJPGDYSIJW-DQNHKJGCSA-N 50097577 (6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid phenylamide::3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid phenylamide::CHEMBL293103 Mu-type opioid receptor Cavia cutleri 740 ChEMBL 10.1016/s0960-894x(03)00295-6 10.7270/Q2FB529V 12749896 Wentland, MP; Sun, X; Ye, Y; Lou, R; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097577&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299841 103994785 CHEMBL293103 ZINC29556310 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50020178 C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)C(N)=O InChI=1S/C19H26N2O/c1-12-17-10-14-5-6-15(18(20)22)9-16(14)19(12,2)7-8-21(17)11-13-3-4-13/h5-6,9,12-13,17H,3-4,7-8,10-11H2,1-2H3,(H2,20,22)/t12-,17?,19-/m0/s1 FAVQVALXVLMHLE-BKBNBNODSA-N 50097579 (6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid amide::8-CAC::8-carboxamidocyclazocine::CHEMBL58646::US9656961, Example 00157 Mu-type opioid receptor Cavia cutleri 0.410000 ChEMBL 10.1016/s0960-894x(03)00295-6 10.7270/Q2FB529V 12749896 Wentland, MP; Sun, X; Ye, Y; Lou, R; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097579 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097579&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10086063 103994787 CHEMBL58646 ZINC29411253 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50020180 CC[C@]12CCN(CC3CC3)C([C@@H]1C)C(=O)c1ccc(NC=O)cc21 InChI=1S/C20H26N2O2/c1-3-20-8-9-22(11-14-4-5-14)18(13(20)2)19(24)16-7-6-15(21-12-23)10-17(16)20/h6-7,10,12-14,18H,3-5,8-9,11H2,1-2H3,(H,21,23)/t13-,18?,20-/m0/s1 OIISUVOSYUTARN-BXBUHSQYSA-N 50128405 CHEMBL299709::N-((6S,11R)-3-Cyclopropylmethyl-6-ethyl-11-methyl-1-oxo-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-formamide Mu-type opioid receptor Cavia cutleri 6.1 ChEMBL 10.1016/s0960-894x(03)00295-6 10.7270/Q2FB529V 12749896 Wentland, MP; Sun, X; Ye, Y; Lou, R; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128405 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128405&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300209 104020170 CHEMBL299709 C06049 ZINC29556297 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50020181 C[C@H]1C2Cc3ccc(NC(=O)c4ccccc4)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C25H30N2O/c1-17-23-14-20-10-11-21(26-24(28)19-6-4-3-5-7-19)15-22(20)25(17,2)12-13-27(23)16-18-8-9-18/h3-7,10-11,15,17-18,23H,8-9,12-14,16H2,1-2H3,(H,26,28)/t17-,23?,25-/m0/s1 VTQNVBWUUURPPT-DQNHKJGCSA-N 50128409 CHEMBL56208::N-((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-benzamide Mu-type opioid receptor Cavia cutleri 570 ChEMBL 10.1016/s0960-894x(03)00295-6 10.7270/Q2FB529V 12749896 Wentland, MP; Sun, X; Ye, Y; Lou, R; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128409 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128409&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300211 104020174 CHEMBL56208 ZINC29556304 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50020184 C[C@H]1[C@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CC1CC1 InChI=1S/C18H25NO/c1-12-17-9-14-5-6-15(20)10-16(14)18(12,2)7-8-19(17)11-13-3-4-13/h5-6,10,12-13,17,20H,3-4,7-9,11H2,1-2H3/t12-,17+,18+/m0/s1 YQYVFVRQLZMJKJ-JBBXEZCESA-N 50001023 (2R,6R,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL56585::Cyclazocine::US10231963, Table B.9::US10736890, Compound TABLE B.9::US11534436, Compound Table B.9::US9656961, Example 00126 Mu-type opioid receptor Cavia cutleri 0.320000 ChEMBL 10.1016/s0960-894x(03)00295-6 10.7270/Q2FB529V 12749896 Wentland, MP; Sun, X; Ye, Y; Lou, R; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001023&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3037926 103915556 CHEMBL56585 ZINC03830613 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50020187 CC[C@]12CCN(CC3CC3)C([C@@H]1C)C(=O)c1ccc(O)cc21 InChI=1S/C19H25NO2/c1-3-19-8-9-20(11-13-4-5-13)17(12(19)2)18(22)15-7-6-14(21)10-16(15)19/h6-7,10,12-13,17,21H,3-5,8-9,11H2,1-2H3/t12-,17?,19-/m0/s1 SEJUQQOPVAUETF-BKBNBNODSA-N 50000091 (6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::(6S,11R)-3-Cyclopropylmethyl-9-hydroxy-6,11-dimethyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one (ethylketocyclazocine)::3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one(Ethylketazocine, EKC)::CHEMBL279968::EKC::EKC(-) Mu-type opioid receptor Cavia cutleri 0.780000 ChEMBL 10.1016/s0960-894x(03)00295-6 10.7270/Q2FB529V 12749896 Wentland, MP; Sun, X; Ye, Y; Lou, R; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000091&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44273397 103914788 CHEMBL279968 ZINC00967957 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50019212 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O InChI=1S/C40H50N8O10/c1-23(44-37(55)29(41)18-25-9-13-27(50)14-10-25)36(54)46-30(19-24-6-3-2-4-7-24)38(56)43-21-34(52)45-31(20-26-11-15-28(51)16-12-26)40(58)48-17-5-8-33(48)39(57)47-32(22-49)35(42)53/h2-4,6-7,9-16,23,29-33,49-51H,5,8,17-22,41H2,1H3,(H2,42,53)(H,43,56)(H,44,55)(H,45,52)(H,46,54)(H,47,57)/t23-,29+,30+,31+,32+,33+/m1/s1 FHZPGIUBXYVUOY-VWGYHWLBSA-N 50059841 (S)-1-[(S)-2-[2-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid ((S)-1-carbamoyl-2-hydroxy-ethyl)-amide::(S)-2-Amino-N-{(R)-1-[(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethylcarbamoyl]-ethyl}-3-(4-hydroxy-phenyl)-propionamide::1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide::1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide (Dermorphin)::1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide(Dermorphin)::CHEMBL278789::DERMORPHIN::Dermorphin;1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide::H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2::Tyr-Ala-Phe-Gly-Tyr-Pro-Ser::YAFGYPS-NH2 Mu-type opioid receptor Cavia cutleri 3.7 ChEMBL 10.1016/s0960-894x(02)00035-5 10.7270/Q2X34WSM 11958984 Ambo, A; Murase, H; Niizuma, H; Ouchi, H; Yamamoto, Y; Sasaki, Y Tohoku Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059841 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059841&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5485199 103955620 CHEMBL278789 ZINC95548678 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50019213 C[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c(C)cccc1C)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O InChI=1S/C42H54N8O10/c1-23-6-4-7-24(2)30(23)20-32(48-38(56)25(3)46-39(57)31(43)18-26-9-13-28(52)14-10-26)40(58)45-21-36(54)47-33(19-27-11-15-29(53)16-12-27)42(60)50-17-5-8-35(50)41(59)49-34(22-51)37(44)55/h4,6-7,9-16,25,31-35,51-53H,5,8,17-22,43H2,1-3H3,(H2,44,55)(H,45,58)(H,46,57)(H,47,54)(H,48,56)(H,49,59)/t25-,31-,32-,33-,34-,35-/m0/s1 OJIZXSLNRWQEAY-UCDZOKANSA-N 50111903 (S)-1-[(S)-2-{2-[(S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-(2,6-dimethyl-phenyl)-propionylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid ((S)-1-carbamoyl-2-hydroxy-ethyl)-amide::CHEMBL355178 Mu-type opioid receptor Cavia cutleri 1.2 ChEMBL 10.1016/s0960-894x(02)00035-5 10.7270/Q2X34WSM 11958984 Ambo, A; Murase, H; Niizuma, H; Ouchi, H; Yamamoto, Y; Sasaki, Y Tohoku Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111903 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111903&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44382026 104006425 CHEMBL355178 ZINC95612159 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50019215 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](Cc1c(C)cccc1C)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C40H58N8O10/c1-20(2)33(39(57)43-19-31(42)50)48-40(58)34(21(3)4)47-37(55)29(15-16-32(51)52)45-38(56)30(18-27-22(5)9-8-10-23(27)6)46-35(53)24(7)44-36(54)28(41)17-25-11-13-26(49)14-12-25/h8-14,20-21,24,28-30,33-34,49H,15-19,41H2,1-7H3,(H2,42,50)(H,43,57)(H,44,54)(H,45,56)(H,46,53)(H,47,55)(H,48,58)(H,51,52)/t24-,28+,29+,30-,33+,34+/m1/s1 VHVQYLMFXQIOOO-FZSYDCBLSA-N 50111904 (S)-4-[(R)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-(2,6-dimethyl-phenyl)-propionylamino]-4-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propylcarbamoyl}-butyric acid::CHEMBL169439 Mu-type opioid receptor Cavia cutleri 8214 ChEMBL 10.1016/s0960-894x(02)00035-5 10.7270/Q2X34WSM 11958984 Ambo, A; Murase, H; Niizuma, H; Ouchi, H; Yamamoto, Y; Sasaki, Y Tohoku Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111904 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111904&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44382612 104006426 CHEMBL169439 ZINC95606201 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50019217 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1c(C)cccc1C)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C40H58N8O10/c1-20(2)33(39(57)43-19-31(42)50)48-40(58)34(21(3)4)47-37(55)29(15-16-32(51)52)45-38(56)30(18-27-22(5)9-8-10-23(27)6)46-35(53)24(7)44-36(54)28(41)17-25-11-13-26(49)14-12-25/h8-14,20-21,24,28-30,33-34,49H,15-19,41H2,1-7H3,(H2,42,50)(H,43,57)(H,44,54)(H,45,56)(H,46,53)(H,47,55)(H,48,58)(H,51,52)/t24-,28-,29-,30-,33-,34-/m0/s1 VHVQYLMFXQIOOO-PHMRRKFASA-N 50111905 (S)-4-[(S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-(2,6-dimethyl-phenyl)-propionylamino]-4-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propylcarbamoyl}-butyric acid::CHEMBL169860 Mu-type opioid receptor Cavia cutleri 6705 ChEMBL 10.1016/s0960-894x(02)00035-5 10.7270/Q2X34WSM 11958984 Ambo, A; Murase, H; Niizuma, H; Ouchi, H; Yamamoto, Y; Sasaki, Y Tohoku Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111905 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111905&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44382611 104006427 CHEMBL169860 ZINC95606213 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50019218 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C37H52N8O10/c1-19(2)30(36(54)40-18-28(39)47)45-37(55)31(20(3)4)44-35(53)27(17-29(48)49)43-34(52)26(16-22-9-7-6-8-10-22)42-32(50)21(5)41-33(51)25(38)15-23-11-13-24(46)14-12-23/h6-14,19-21,25-27,30-31,46H,15-18,38H2,1-5H3,(H2,39,47)(H,40,54)(H,41,51)(H,42,50)(H,43,52)(H,44,53)(H,45,55)(H,48,49)/t21-,25+,26+,27+,30+,31+/m1/s1 CJAORFIPPWIGPG-QXYJMILXSA-N 50001468 (S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::3-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL317956::H-Tyr-D-Ala-Phe-Asp-Val-Val-Gly-NH2::deltorphin C Mu-type opioid receptor Cavia cutleri 5437 ChEMBL 10.1016/s0960-894x(02)00035-5 10.7270/Q2X34WSM 11958984 Ambo, A; Murase, H; Niizuma, H; Ouchi, H; Yamamoto, Y; Sasaki, Y Tohoku Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001468&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10055958 103915933 CHEMBL317956 C18097 ZINC95610551 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50019219 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c(C)cccc1C)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O InChI=1S/C42H54N8O10/c1-23-6-4-7-24(2)30(23)20-32(48-38(56)25(3)46-39(57)31(43)18-26-9-13-28(52)14-10-26)40(58)45-21-36(54)47-33(19-27-11-15-29(53)16-12-27)42(60)50-17-5-8-35(50)41(59)49-34(22-51)37(44)55/h4,6-7,9-16,25,31-35,51-53H,5,8,17-22,43H2,1-3H3,(H2,44,55)(H,45,58)(H,46,57)(H,47,54)(H,48,56)(H,49,59)/t25-,31+,32+,33+,34+,35+/m1/s1 OJIZXSLNRWQEAY-CATITNMPSA-N 50111906 (S)-1-[(S)-2-{2-[(R)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-(2,6-dimethyl-phenyl)-propionylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid ((S)-1-carbamoyl-2-hydroxy-ethyl)-amide::CHEMBL168110 Mu-type opioid receptor Cavia cutleri 44 ChEMBL 10.1016/s0960-894x(02)00035-5 10.7270/Q2X34WSM 11958984 Ambo, A; Murase, H; Niizuma, H; Ouchi, H; Yamamoto, Y; Sasaki, Y Tohoku Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111906 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111906&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44381968 104006428 CHEMBL168110 ZINC95543600 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50022867 Oc1ccc2C[C@H]3N(CC4CC4)CCC45C(Oc1c24)c1[nH]c2ccccc2c1CC35O InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1 WIYUZYBFCWCCQJ-XEWUMVRVSA-N 21864 (21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.0^{1,13}.0^{2,21}.0^{4,12}.0^{5,10}.0^{19,25}]pentacosa-4(12),5,7,9,15,17,19(25)-heptaene-2,16-diol::(8R)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol::NALTRINDOLE::[3H]-naltrindole Mu-type opioid receptor Cavia cutleri 1.8 ChEMBL 10.1016/s0960-894x(02)00934-4 10.7270/Q27S7P9P 12565965 Ananthan, S; Kezar, HS; Saini, SK; Khare, NK; Davis, P; Dersch, CM; Porreca, F; Rothman, RB Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21864&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3034754 49700969 ZINC62153992 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50022869 NC(N)=Nc1cnc2[C@@H]3Oc4c5c(C[C@H]6N(CC7CC7)CC[C@@]35[C@@]6(O)Cc2c1)ccc4O InChI=1S/C24H27N5O3/c25-22(26)28-15-7-14-9-24(31)17-8-13-3-4-16(30)20-18(13)23(24,21(32-20)19(14)27-10-15)5-6-29(17)11-12-1-2-12/h3-4,7,10,12,17,21,30-31H,1-2,5-6,8-9,11H2,(H4,25,26,28)/t17-,21+,23+,24-/m1/s1 FZJHXKMITTVIBA-DVNJHFJZSA-N 50123274 6-amino(imino)methylamino-19-cyclopropylmethyl-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaene-2,13-diol; ditrifluoracetic acid::CHEMBL348011 Mu-type opioid receptor Cavia cutleri 6.1 ChEMBL 10.1016/s0960-894x(02)00934-4 10.7270/Q27S7P9P 12565965 Ananthan, S; Kezar, HS; Saini, SK; Khare, NK; Davis, P; Dersch, CM; Porreca, F; Rothman, RB Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123274 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123274&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10071523 104015792 CHEMBL348011 ZINC13487528 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50022872 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2[C@@H]4Oc6c7c(C[C@H]8N(CC9CC9)CC[C@@]47[C@@]8(O)Cc2c1C[C@@]35O)ccc6O InChI=1S/C40H43N3O6/c44-25-7-5-21-13-27-39(46)15-23-24-16-40(47)28-14-22-6-8-26(45)34-30(22)38(40,10-12-43(28)18-20-3-4-20)36(49-34)32(24)41-31(23)35-37(39,29(21)33(25)48-35)9-11-42(27)17-19-1-2-19/h5-8,19-20,27-28,35-36,41,44-47H,1-4,9-18H2/t27-,28-,35+,36+,37+,38+,39-,40-/m1/s1 APSUXPSYBJVPPS-YAUKWVCOSA-N 82551 C18130::CAS_105618-26-6::NOR-BNI (HCI)2::NORBNI Mu-type opioid receptor Cavia cutleri 15 ChEMBL 10.1016/s0960-894x(02)00934-4 10.7270/Q27S7P9P 12565965 Ananthan, S; Kezar, HS; Saini, SK; Khare, NK; Davis, P; Dersch, CM; Porreca, F; Rothman, RB Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82551&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5480230 136350521 C18130 ZINC03995590 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50022879 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(cc1C[C@@]35O)-n1cccc1 InChI=1S/C27H27N3O3/c31-20-6-5-17-12-21-27(32)13-18-11-19(29-8-1-2-9-29)14-28-23(18)25-26(27,22(17)24(20)33-25)7-10-30(21)15-16-3-4-16/h1-2,5-6,8-9,11,14,16,21,25,31-32H,3-4,7,10,12-13,15H2/t21-,25+,26+,27-/m1/s1 AQPCHMHRVHPFAE-NVSKSXHLSA-N 50123279 19-cyclopropylmethyl-6-(1H-1-pyrrolyl)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaene-2,13-diol::CHEMBL346165 Mu-type opioid receptor Cavia cutleri 4.2 ChEMBL 10.1016/s0960-894x(02)00934-4 10.7270/Q27S7P9P 12565965 Ananthan, S; Kezar, HS; Saini, SK; Khare, NK; Davis, P; Dersch, CM; Porreca, F; Rothman, RB Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123279 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123279&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10433421 104015797 CHEMBL346165 ZINC13487527 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50026468 CN1CCC[C@@]11CCCC[C@@H]1NC(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C18H24Cl2N2O/c1-22-10-4-9-18(22)8-3-2-5-16(18)21-17(23)12-13-6-7-14(19)15(20)11-13/h6-7,11,16H,2-5,8-10,12H2,1H3,(H,21,23)/t16-,18+/m0/s1 ACJWWDOSBNCLFC-FUHWJXTLSA-N 50017074 2-(3,4-Dichloro-phenyl)-N-(1-methyl-1-aza-spiro[4.5]dec-6-yl)-acetamide::CHEMBL25493 Mu-type opioid receptor Cavia cutleri 250 ChEMBL 10.1021/jm00126a019 10.7270/Q280536X 2542556 Fujimoto, RA; Boxer, J; Jackson, RH; Simke, JP; Neale, RF; Snowhill, EW; Barbaz, BJ; Williams, M; Sills, MA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017074&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14548227 103928402 CHEMBL25493 ZINC28256979 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50024321 Cc1cccc(C)c1C[C@@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCCC(N)=O InChI=1S/C29H42N8O4/c1-18-8-6-9-19(2)21(18)17-22(30)26(39)36-23(12-7-14-35-29(32)33)28(41)37-24(16-20-10-4-3-5-11-20)27(40)34-15-13-25(31)38/h3-6,8-11,22-24H,7,12-17,30H2,1-2H3,(H2,31,38)(H,34,40)(H,36,39)(H,37,41)(H4,32,33,35)/t22-,23-,24+/m1/s1 GKYITRXFIIFDSO-SMIHKQSGSA-N 50126002 (R)-2-[(R)-2-Amino-3-(2,6-dimethyl-phenyl)-propionylamino]-5-guanidino-pentanoic acid [(S)-1-(2-carbamoyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL23295 Mu-type opioid receptor Cavia cutleri 320 ChEMBL 10.1016/s0960-894x(03)00110-0 10.7270/Q2XS5TQ5 12657261 Ambo, A; Niizuma, H; Sasaki, A; Kohara, H; Sasaki, Y Tohoku Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126002 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126002&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44459286 104018145 CHEMBL23295 ZINC28262389 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50024322 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCCC(N)=O InChI=1S/C27H38N8O5/c28-20(15-18-8-10-19(36)11-9-18)24(38)34-21(7-4-13-33-27(30)31)26(40)35-22(16-17-5-2-1-3-6-17)25(39)32-14-12-23(29)37/h1-3,5-6,8-11,20-22,36H,4,7,12-16,28H2,(H2,29,37)(H,32,39)(H,34,38)(H,35,40)(H4,30,31,33)/t20-,21+,22-/m0/s1 OJIVGUBQABAVAH-BDTNDASRSA-N 50125998 (R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-5-guanidino-pentanoic acid [(S)-1-(2-carbamoyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL22321 Mu-type opioid receptor Cavia cutleri 5.3 ChEMBL 10.1016/s0960-894x(03)00110-0 10.7270/Q2XS5TQ5 12657261 Ambo, A; Niizuma, H; Sasaki, A; Kohara, H; Sasaki, Y Tohoku Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125998 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125998&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 132137 104018141 CHEMBL22321 ZINC28261804 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50024323 Cc1cccc(C)c1C[C@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCCC(N)=O InChI=1S/C29H42N8O5/c1-17-5-3-6-18(2)21(17)16-24(27(41)34-14-12-25(31)39)37-28(42)23(7-4-13-35-29(32)33)36-26(40)22(30)15-19-8-10-20(38)11-9-19/h3,5-6,8-11,22-24,38H,4,7,12-16,30H2,1-2H3,(H2,31,39)(H,34,41)(H,36,40)(H,37,42)(H4,32,33,35)/t22-,23+,24-/m0/s1 VTTYRTQVGKYUDG-VXNXHJTFSA-N 50126003 (R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-5-guanidino-pentanoic acid [(S)-1-(2-carbamoyl-ethylcarbamoyl)-2-(2,6-dimethyl-phenyl)-ethyl]-amide::CHEMBL23836 Mu-type opioid receptor Cavia cutleri 1.7 ChEMBL 10.1016/s0960-894x(03)00110-0 10.7270/Q2XS5TQ5 12657261 Ambo, A; Niizuma, H; Sasaki, A; Kohara, H; Sasaki, Y Tohoku Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126003 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126003&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44458913 104018146 CHEMBL23836 ZINC28259154 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50024324 Cc1cccc(C)c1C[C@@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCCC(N)=O InChI=1S/C29H42N8O5/c1-17-5-3-6-18(2)21(17)16-24(27(41)34-14-12-25(31)39)37-28(42)23(7-4-13-35-29(32)33)36-26(40)22(30)15-19-8-10-20(38)11-9-19/h3,5-6,8-11,22-24,38H,4,7,12-16,30H2,1-2H3,(H2,31,39)(H,34,41)(H,36,40)(H,37,42)(H4,32,33,35)/t22-,23+,24+/m0/s1 VTTYRTQVGKYUDG-RBZQAINGSA-N 50125997 (R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-5-guanidino-pentanoic acid [(R)-1-(2-carbamoyl-ethylcarbamoyl)-2-(2,6-dimethyl-phenyl)-ethyl]-amide::CHEMBL23133 Mu-type opioid receptor Cavia cutleri 20 ChEMBL 10.1016/s0960-894x(03)00110-0 10.7270/Q2XS5TQ5 12657261 Ambo, A; Niizuma, H; Sasaki, A; Kohara, H; Sasaki, Y Tohoku Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125997 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125997&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44459052 104018140 CHEMBL23133 ZINC28262084 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50024325 Cc1cccc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c(C)cccc1C)C(=O)NCCC(N)=O InChI=1S/C31H46N8O4/c1-18-8-5-9-19(2)22(18)16-24(32)28(41)38-25(12-7-14-37-31(34)35)30(43)39-26(29(42)36-15-13-27(33)40)17-23-20(3)10-6-11-21(23)4/h5-6,8-11,24-26H,7,12-17,32H2,1-4H3,(H2,33,40)(H,36,42)(H,38,41)(H,39,43)(H4,34,35,37)/t24-,25+,26-/m0/s1 OELGUIBMBJLJPS-NXCFDTQHSA-N 50126000 (R)-2-[(S)-2-Amino-3-(2,6-dimethyl-phenyl)-propionylamino]-5-guanidino-pentanoic acid [(S)-1-(2-carbamoyl-ethylcarbamoyl)-2-(2,6-dimethyl-phenyl)-ethyl]-amide::CHEMBL24059 Mu-type opioid receptor Cavia cutleri 2.8 ChEMBL 10.1016/s0960-894x(03)00110-0 10.7270/Q2XS5TQ5 12657261 Ambo, A; Niizuma, H; Sasaki, A; Kohara, H; Sasaki, Y Tohoku Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126000&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44459293 104018143 CHEMBL24059 ZINC28755318 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50024326 N[C@@H](Cc1ccccc1)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCCC(N)=O InChI=1S/C27H38N8O4/c28-20(16-18-8-3-1-4-9-18)24(37)34-21(12-7-14-33-27(30)31)26(39)35-22(17-19-10-5-2-6-11-19)25(38)32-15-13-23(29)36/h1-6,8-11,20-22H,7,12-17,28H2,(H2,29,36)(H,32,38)(H,34,37)(H,35,39)(H4,30,31,33)/t20-,21+,22-/m0/s1 HLNBZYKOBLAYTJ-BDTNDASRSA-N 50126001 (R)-2-((S)-2-Amino-3-phenyl-propionylamino)-5-guanidino-pentanoic acid [(S)-1-(2-carbamoyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL23325 Mu-type opioid receptor Cavia cutleri 633 ChEMBL 10.1016/s0960-894x(03)00110-0 10.7270/Q2XS5TQ5 12657261 Ambo, A; Niizuma, H; Sasaki, A; Kohara, H; Sasaki, Y Tohoku Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126001 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126001&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44459289 104018144 CHEMBL23325 ZINC28264169 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50024327 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCCC(N)=O InChI=1S/C29H42N8O5/c1-17-13-20(38)14-18(2)21(17)16-22(30)26(40)36-23(9-6-11-35-29(32)33)28(42)37-24(15-19-7-4-3-5-8-19)27(41)34-12-10-25(31)39/h3-5,7-8,13-14,22-24,38H,6,9-12,15-16,30H2,1-2H3,(H2,31,39)(H,34,41)(H,36,40)(H,37,42)(H4,32,33,35)/t22-,23+,24-/m0/s1 NWHQVSLALRZRQM-VXNXHJTFSA-N 50125999 (R)-2-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionylamino]-5-guanidino-pentanoic acid [(S)-1-(2-carbamoyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL23362 Mu-type opioid receptor Cavia cutleri 0.034000 ChEMBL 10.1016/s0960-894x(03)00110-0 10.7270/Q2XS5TQ5 12657261 Ambo, A; Niizuma, H; Sasaki, A; Kohara, H; Sasaki, Y Tohoku Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125999 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125999&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10698509 104018142 CHEMBL23362 ZINC28264828 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50024328 Cc1cccc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCCC(N)=O InChI=1S/C29H42N8O4/c1-18-8-6-9-19(2)21(18)17-22(30)26(39)36-23(12-7-14-35-29(32)33)28(41)37-24(16-20-10-4-3-5-11-20)27(40)34-15-13-25(31)38/h3-6,8-11,22-24H,7,12-17,30H2,1-2H3,(H2,31,38)(H,34,40)(H,36,39)(H,37,41)(H4,32,33,35)/t22-,23+,24-/m0/s1 GKYITRXFIIFDSO-VXNXHJTFSA-N 50125996 (R)-2-[(S)-2-Amino-3-(2,6-dimethyl-phenyl)-propionylamino]-5-guanidino-pentanoic acid [(S)-1-(2-carbamoyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL280178 Mu-type opioid receptor Cavia cutleri 9.9 ChEMBL 10.1016/s0960-894x(03)00110-0 10.7270/Q2XS5TQ5 12657261 Ambo, A; Niizuma, H; Sasaki, A; Kohara, H; Sasaki, Y Tohoku Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125996&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10483052 104018139 CHEMBL280178 ZINC28264832 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031086 CNC(=N)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC[S+](C)[O-])C(=O)N[C@@H](Cc1ccccc1)C(=O)NC(C)C(=O)OC InChI=1S/C29H40N6O7S/c1-18(28(40)42-3)32-26(38)23(16-19-8-6-5-7-9-19)34-25(37)22(14-15-43(4)41)33-27(39)24(35-29(30)31-2)17-20-10-12-21(36)13-11-20/h5-13,18,22-24,36H,14-17H2,1-4H3,(H,32,38)(H,33,39)(H,34,37)(H3,30,31,35)/t18?,22-,23-,24-,43?/m0/s1 ZSOUCXHBVUTCNF-WKYCEPGPSA-N 50019838 2-(2-{2-[3-(4-Hydroxy-phenyl)-2-(N'-methyl-guanidino)-propionylamino]-4-methanesulfinyl-butyrylamino}-3-phenyl-propionylamino)-propionic acid methyl ester::CHEMBL2372389 Mu-type opioid receptor Cavia cutleri 280 ChEMBL 10.1021/jm00392a002 10.7270/Q20Z73VC 2887656 Marastoni, M; Salvadori, S; Balboni, G; Borea, PA; Marzola, G; Tomatis, R TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019838 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019838&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73345676 103930761 CHEMBL2372389 ZINC36221784 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031087 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 4 ChEMBL 10.1021/jm00392a002 10.7270/Q20Z73VC 2887656 Marastoni, M; Salvadori, S; Balboni, G; Borea, PA; Marzola, G; Tomatis, R TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031088 COC(=O)CN(C)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC[S+](C)[O-])NC(=O)[C@H](Cc1ccc(O)cc1)N=C(N)N InChI=1S/C28H38N6O7S/c1-34(17-24(36)41-2)27(39)23(16-18-7-5-4-6-8-18)32-25(37)21(13-14-42(3)40)31-26(38)22(33-28(29)30)15-19-9-11-20(35)12-10-19/h4-12,21-23,35H,13-17H2,1-3H3,(H,31,38)(H,32,37)(H4,29,30,33)/t21-,22-,23-,42?/m0/s1 AVGMCYZFGPJTPW-VGORAETMSA-N 50019830 CHEMBL2372395::[(2-{2-[2-Guanidino-3-(4-hydroxy-phenyl)-propionylamino]-4-methanesulfinyl-butyrylamino}-3-phenyl-propionyl)-methyl-amino]-acetic acid methyl ester Mu-type opioid receptor Cavia cutleri 23 ChEMBL 10.1021/jm00392a002 10.7270/Q20Z73VC 2887656 Marastoni, M; Salvadori, S; Balboni, G; Borea, PA; Marzola, G; Tomatis, R TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019830 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019830&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73345679 103930753 CHEMBL2372395 ZINC29326131 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031089 CN(CC(N)=O)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC[S+](C)[O-])NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C26H35N5O6S/c1-31(16-23(28)33)26(36)22(15-17-6-4-3-5-7-17)30-25(35)21(12-13-38(2)37)29-24(34)20(27)14-18-8-10-19(32)11-9-18/h3-11,20-22,32H,12-16,27H2,1-2H3,(H2,28,33)(H,29,34)(H,30,35)/t20-,21-,22-,38?/m0/s1 RSBNAOOCIFSYBS-QJIWBYFKSA-N 50019831 2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-N-[1-(carbamoylmethyl-methyl-carbamoyl)-2-phenyl-ethyl]-4-methanesulfinyl-butyramide::CHEMBL2372394 Mu-type opioid receptor Cavia cutleri 6 ChEMBL 10.1021/jm00392a002 10.7270/Q20Z73VC 2887656 Marastoni, M; Salvadori, S; Balboni, G; Borea, PA; Marzola, G; Tomatis, R TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019831 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019831&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73356293 103930754 CHEMBL2372394 ZINC29326111 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031090 CC(NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC[S+](C)[O-])NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C26H34N4O7S/c1-16(26(35)36)28-25(34)22(15-17-6-4-3-5-7-17)30-24(33)21(12-13-38(2)37)29-23(32)20(27)14-18-8-10-19(31)11-9-18/h3-11,16,20-22,31H,12-15,27H2,1-2H3,(H,28,34)(H,29,32)(H,30,33)(H,35,36)/t16?,20-,21-,22-,38?/m0/s1 MBZDHMSAEWWRFD-LNILZMDTSA-N 50019833 2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-4-methanesulfinyl-butyrylamino}-3-phenyl-propionylamino)-propionic acid::CHEMBL2372393 Mu-type opioid receptor Cavia cutleri 120 ChEMBL 10.1021/jm00392a002 10.7270/Q20Z73VC 2887656 Marastoni, M; Salvadori, S; Balboni, G; Borea, PA; Marzola, G; Tomatis, R TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019833&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73348687 103930756 CHEMBL2372393 C01960 ZINC36221758 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031091 COC(=O)C(C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC[S+](C)[O-])NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C27H36N4O7S/c1-17(27(36)38-2)29-26(35)23(16-18-7-5-4-6-8-18)31-25(34)22(13-14-39(3)37)30-24(33)21(28)15-19-9-11-20(32)12-10-19/h4-12,17,21-23,32H,13-16,28H2,1-3H3,(H,29,35)(H,30,33)(H,31,34)/t17?,21-,22-,23-,39?/m0/s1 GFSQQKCPLXCYPT-PUWBHAJGSA-N 50019835 2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-4-methanesulfinyl-butyrylamino}-3-phenyl-propionylamino)-propionic acid methyl ester::CHEMBL2372392 Mu-type opioid receptor Cavia cutleri 9 ChEMBL 10.1021/jm00392a002 10.7270/Q20Z73VC 2887656 Marastoni, M; Salvadori, S; Balboni, G; Borea, PA; Marzola, G; Tomatis, R TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019835&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73345678 103930758 CHEMBL2372392 ZINC36221771 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031102 COC(=O)CN(C)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC[S+](C)[O-])NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C27H36N4O7S/c1-31(17-24(33)38-2)27(36)23(16-18-7-5-4-6-8-18)30-26(35)22(13-14-39(3)37)29-25(34)21(28)15-19-9-11-20(32)12-10-19/h4-12,21-23,32H,13-17,28H2,1-3H3,(H,29,34)(H,30,35)/t21-,22-,23-,39?/m0/s1 AKYCNGLBGGKTAX-JBIUMHCQSA-N 50019836 CHEMBL2372400::[(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-4-methanesulfinyl-butyrylamino}-3-phenyl-propionyl)-methyl-amino]-acetic acid methyl ester Mu-type opioid receptor Cavia cutleri 6 ChEMBL 10.1021/jm00392a002 10.7270/Q20Z73VC 2887656 Marastoni, M; Salvadori, S; Balboni, G; Borea, PA; Marzola, G; Tomatis, R TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019836&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73354764 103930759 CHEMBL2372400 ZINC29332463 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031105 C[S+]([O-])CC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)N=C(N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(N)=O InChI=1S/C26H35N7O6S/c1-40(39)12-11-19(31-25(38)21(33-26(28)29)14-17-7-9-18(34)10-8-17)24(37)32-20(23(36)30-15-22(27)35)13-16-5-3-2-4-6-16/h2-10,19-21,34H,11-15H2,1H3,(H2,27,35)(H,30,36)(H,31,38)(H,32,37)(H4,28,29,33)/t19-,20-,21-,40?/m0/s1 NSYBRHSOFZCYKH-RUCILLRTSA-N 50019829 CHEMBL2372402::N-[1-(Carbamoylmethyl-carbamoyl)-2-phenyl-ethyl]-2-[2-guanidino-3-(4-hydroxy-phenyl)-propionylamino]-4-methanesulfinyl-butyramide Mu-type opioid receptor Cavia cutleri 5 ChEMBL 10.1021/jm00392a002 10.7270/Q20Z73VC 2887656 Marastoni, M; Salvadori, S; Balboni, G; Borea, PA; Marzola, G; Tomatis, R TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019829 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019829&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73354765 103930752 CHEMBL2372402 ZINC29333264 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031107 CN(CC(O)=O)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC[S+](C)[O-])NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C26H34N4O7S/c1-30(16-23(32)33)26(36)22(15-17-6-4-3-5-7-17)29-25(35)21(12-13-38(2)37)28-24(34)20(27)14-18-8-10-19(31)11-9-18/h3-11,20-22,31H,12-16,27H2,1-2H3,(H,28,34)(H,29,35)(H,32,33)/t20-,21-,22-,38?/m0/s1 XXFHUWHJQJDUCI-QJIWBYFKSA-N 50019827 CHEMBL2372401::[(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-4-methanesulfinyl-butyrylamino}-3-phenyl-propionyl)-methyl-amino]-acetic acid Mu-type opioid receptor Cavia cutleri 77 ChEMBL 10.1021/jm00392a002 10.7270/Q20Z73VC 2887656 Marastoni, M; Salvadori, S; Balboni, G; Borea, PA; Marzola, G; Tomatis, R TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019827 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019827&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73356294 103930750 CHEMBL2372401 ZINC29333247 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031108 COC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC[S+](C)[O-])NC(=O)[C@H](Cc1ccc(O)cc1)N=C(N)N InChI=1S/C27H36N6O7S/c1-40-23(35)16-30-24(36)21(14-17-6-4-3-5-7-17)32-25(37)20(12-13-41(2)39)31-26(38)22(33-27(28)29)15-18-8-10-19(34)11-9-18/h3-11,20-22,34H,12-16H2,1-2H3,(H,30,36)(H,31,38)(H,32,37)(H4,28,29,33)/t20-,21-,22-,41?/m0/s1 RRKLITDRRHHDOM-BIPRHWAESA-N 50019832 (2-{2-[2-Guanidino-3-(4-hydroxy-phenyl)-propionylamino]-4-methanesulfinyl-butyrylamino}-3-phenyl-propionylamino)-acetic acid methyl ester::CHEMBL2372403 Mu-type opioid receptor Cavia cutleri 24 ChEMBL 10.1021/jm00392a002 10.7270/Q20Z73VC 2887656 Marastoni, M; Salvadori, S; Balboni, G; Borea, PA; Marzola, G; Tomatis, R TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019832 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019832&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73348689 103930755 CHEMBL2372403 ZINC29330471 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031109 C[S+]([O-])CC[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(O)=O InChI=1S/C25H32N4O7S/c1-37(36)12-11-20(28-23(33)19(26)13-17-7-9-18(30)10-8-17)25(35)29-21(24(34)27-15-22(31)32)14-16-5-3-2-4-6-16/h2-10,19-21,30H,11-15,26H2,1H3,(H,27,34)(H,28,33)(H,29,35)(H,31,32)/t19-,20-,21-,37?/m0/s1 BAKAWBMTKDZQCH-GGRUBCQMSA-N 50019840 (2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-4-methanesulfinyl-butyrylamino}-3-phenyl-propionylamino)-acetic acid::CHEMBL2372388 Mu-type opioid receptor Cavia cutleri 61 ChEMBL 10.1021/jm00392a002 10.7270/Q20Z73VC 2887656 Marastoni, M; Salvadori, S; Balboni, G; Borea, PA; Marzola, G; Tomatis, R TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019840 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019840&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73354763 103930763 CHEMBL2372388 ZINC29327886 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031110 COC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC[S+](C)[O-])NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C26H34N4O7S/c1-37-23(32)16-28-25(34)22(15-17-6-4-3-5-7-17)30-26(35)21(12-13-38(2)36)29-24(33)20(27)14-18-8-10-19(31)11-9-18/h3-11,20-22,31H,12-16,27H2,1-2H3,(H,28,34)(H,29,33)(H,30,35)/t20-,21-,22-,38?/m0/s1 ALBLNOUHKYJANB-QJIWBYFKSA-N 50019839 (2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-4-methanesulfinyl-butyrylamino}-3-phenyl-propionylamino)-acetic acid methyl ester::CHEMBL2372387 Mu-type opioid receptor Cavia cutleri 5 ChEMBL 10.1021/jm00392a002 10.7270/Q20Z73VC 2887656 Marastoni, M; Salvadori, S; Balboni, G; Borea, PA; Marzola, G; Tomatis, R TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019839 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019839&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73345675 103930762 CHEMBL2372387 ZINC29327866 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031114 C[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(N)=O InChI=1S/C23H29N5O5/c1-14(27-22(32)18(24)11-16-7-9-17(29)10-8-16)21(31)28-19(23(33)26-13-20(25)30)12-15-5-3-2-4-6-15/h2-10,14,18-19,29H,11-13,24H2,1H3,(H2,25,30)(H,26,33)(H,27,32)(H,28,31)/t14-,18-,19-/m0/s1 JWZLANUHRXGDET-JVPBZIDWSA-N 50019828 CHEMBL290737::Dermorphin(1-4)amide Mu-type opioid receptor Cavia cutleri 37 ChEMBL 10.1021/jm00392a002 10.7270/Q20Z73VC 2887656 Marastoni, M; Salvadori, S; Balboni, G; Borea, PA; Marzola, G; Tomatis, R TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019828 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019828&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5487533 103930751 CHEMBL290737 ZINC29329979 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031126 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O InChI=1S/C40H50N8O10/c1-23(44-37(55)29(41)18-25-9-13-27(50)14-10-25)36(54)46-30(19-24-6-3-2-4-7-24)38(56)43-21-34(52)45-31(20-26-11-15-28(51)16-12-26)40(58)48-17-5-8-33(48)39(57)47-32(22-49)35(42)53/h2-4,6-7,9-16,23,29-33,49-51H,5,8,17-22,41H2,1H3,(H2,42,53)(H,43,56)(H,44,55)(H,45,52)(H,46,54)(H,47,57)/t23-,29+,30+,31+,32+,33+/m1/s1 FHZPGIUBXYVUOY-VWGYHWLBSA-N 50059841 (S)-1-[(S)-2-[2-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid ((S)-1-carbamoyl-2-hydroxy-ethyl)-amide::(S)-2-Amino-N-{(R)-1-[(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethylcarbamoyl]-ethyl}-3-(4-hydroxy-phenyl)-propionamide::1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide::1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide (Dermorphin)::1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide(Dermorphin)::CHEMBL278789::DERMORPHIN::Dermorphin;1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide::H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2::Tyr-Ala-Phe-Gly-Tyr-Pro-Ser::YAFGYPS-NH2 Mu-type opioid receptor Cavia cutleri 5.7 ChEMBL 10.1021/jm00392a002 10.7270/Q20Z73VC 2887656 Marastoni, M; Salvadori, S; Balboni, G; Borea, PA; Marzola, G; Tomatis, R TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059841 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059841&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5485199 103955620 CHEMBL278789 ZINC95548678 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50028968 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C77H109N23O13/c1-44(2)36-59(97-69(107)60(38-45-16-4-3-5-17-45)98-70(108)61(39-47-41-89-53-20-8-6-18-50(47)53)92-64(102)43-91-65(103)52(79)37-46-27-29-49(101)30-28-46)68(106)94-55(23-12-32-86-75(80)81)66(104)93-56(24-13-33-87-76(82)83)67(105)99-62(40-48-42-90-54-21-9-7-19-51(48)54)71(109)95-57(25-14-34-88-77(84)85)73(111)100-35-15-26-63(100)72(110)96-58(74(112)113)22-10-11-31-78/h3-9,16-21,27-30,41-42,44,52,55-63,89-90,101H,10-15,22-26,31-40,43,78-79H2,1-2H3,(H,91,103)(H,92,102)(H,93,104)(H,94,106)(H,95,109)(H,96,110)(H,97,107)(H,98,108)(H,99,105)(H,112,113)(H4,80,81,86)(H4,82,83,87)(H4,84,85,88)/t52-,55-,56-,57-,58-,59-,60-,61+,62+,63+/m0/s1 IECSPHHJDKRMOG-JRAGJKLTSA-N 50452248 CHEMBL3037891 Mu-type opioid receptor Cavia cutleri 222 ChEMBL 10.1021/jm00160a019 10.7270/Q2Z89BCJ 2876099 Gairin, JE; Mazarguil, H; Alvinerie, P; Saint-Pierre, S; Meunier, JC; Cros, J TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452248 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452248&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73346658 225145619 CHEMBL3037891 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50029991 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(O)=O InChI=1S/C99H154N30O24/c1-7-55(6)81(128-86(142)66(28-18-40-111-98(106)107)117-83(139)65(27-17-39-110-97(104)105)119-88(144)70(44-54(4)5)124-89(145)71(46-56-21-9-8-10-22-56)116-78(133)52-114-77(132)51-115-82(138)61(102)45-57-31-33-59(130)34-32-57)94(150)121-67(29-19-41-112-99(108)109)95(151)129-42-20-30-75(129)93(149)120-64(26-14-16-38-101)85(141)123-69(43-53(2)3)87(143)118-63(25-13-15-37-100)84(140)125-72(47-58-50-113-62-24-12-11-23-60(58)62)90(146)127-74(49-80(136)137)92(148)126-73(48-76(103)131)91(147)122-68(96(152)153)35-36-79(134)135/h8-12,21-24,31-34,50,53-55,61,63-75,81,113,130H,7,13-20,25-30,35-49,51-52,100-102H2,1-6H3,(H2,103,131)(H,114,132)(H,115,138)(H,116,133)(H,117,139)(H,118,143)(H,119,144)(H,120,149)(H,121,150)(H,122,147)(H,123,141)(H,124,145)(H,125,140)(H,126,148)(H,127,146)(H,128,142)(H,134,135)(H,136,137)(H,152,153)(H4,104,105,110)(H4,106,107,111)(H4,108,109,112)/t55-,61-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,81-/m0/s1 SNYRSILPNZIHHZ-FIXZTSJVSA-N 50019481 CHEMBL2028997::NH2-Tyr-Gly-Gly-Phe-D-Trp-Arg-Arg-D-Trp-Arg-D-Pro-Lys-OH Mu-type opioid receptor Cavia cutleri 0.280000 ChEMBL 10.1021/jm00160a019 10.7270/Q2Z89BCJ 2876099 Gairin, JE; Mazarguil, H; Alvinerie, P; Saint-Pierre, S; Meunier, JC; Cros, J TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019481 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019481&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 70685720 103930431 CHEMBL2028997 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50029992 CC(C)C[C@H](NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C70H103N23O13/c1-39(2)31-53(91-63(101)54(33-41-35-82-47-15-5-3-13-44(41)47)86-58(96)38-84-57(95)37-85-59(97)46(72)32-40-22-24-43(94)25-23-40)62(100)88-49(18-9-27-79-68(73)74)60(98)87-50(19-10-28-80-69(75)76)61(99)92-55(34-42-36-83-48-16-6-4-14-45(42)48)64(102)89-51(20-11-29-81-70(77)78)66(104)93-30-12-21-56(93)65(103)90-52(67(105)106)17-7-8-26-71/h3-6,13-16,22-25,35-36,39,46,49-56,82-83,94H,7-12,17-21,26-34,37-38,71-72H2,1-2H3,(H,84,95)(H,85,97)(H,86,96)(H,87,98)(H,88,100)(H,89,102)(H,90,103)(H,91,101)(H,92,99)(H,105,106)(H4,73,74,79)(H4,75,76,80)(H4,77,78,81)/t46-,49-,50-,51-,52-,53-,54+,55+,56+/m0/s1 PAYBLKYPEZHEQC-WOSAKMDBSA-N 50019483 CHEMBL2373008::NH2-Tyr-Gly-D-Trp-Phe-Leu-Arg-Arg-D-Trp-Arg-D-Pro-Lys-OH Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm00160a019 10.7270/Q2Z89BCJ 2876099 Gairin, JE; Mazarguil, H; Alvinerie, P; Saint-Pierre, S; Meunier, JC; Cros, J TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019483&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73350321 103930433 CHEMBL2373008 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50029996 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C63H103N21O13/c1-5-37(4)51(58(94)80-44(20-13-29-74-63(70)71)59(95)84-30-14-21-48(84)57(93)81-45(60(96)97)17-9-10-26-64)83-54(90)43(19-12-28-73-62(68)69)78-53(89)42(18-11-27-72-61(66)67)79-55(91)46(31-36(2)3)82-56(92)47(33-38-15-7-6-8-16-38)77-50(87)35-75-49(86)34-76-52(88)41(65)32-39-22-24-40(85)25-23-39/h6-8,15-16,22-25,36-37,41-48,51,85H,5,9-14,17-21,26-35,64-65H2,1-4H3,(H,75,86)(H,76,88)(H,77,87)(H,78,89)(H,79,91)(H,80,94)(H,81,93)(H,82,92)(H,83,90)(H,96,97)(H4,66,67,72)(H4,68,69,73)(H4,70,71,74)/t37-,41-,42-,43-,44-,45-,46-,47-,48+,51-/m0/s1 WZHQALIQGVYQGG-DTQUPHKSSA-N 50019484 CHEMBL384584::NH2-Tyr-D-Trp-Gly-Phe-Leu-Arg-Arg-D-Trp-Arg-D-Pro-Lys-OH Mu-type opioid receptor Cavia cutleri 3.3 ChEMBL 10.1021/jm00160a019 10.7270/Q2Z89BCJ 2876099 Gairin, JE; Mazarguil, H; Alvinerie, P; Saint-Pierre, S; Meunier, JC; Cros, J TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019484&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10351514 103930434 CHEMBL384584 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031487 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)[C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O InChI=1S/C34H48N6O10/c1-18(2)14-25(32(47)40-29(20(4)42)34(49)50)38-31(46)26(16-21-8-6-5-7-9-21)37-27(44)17-36-33(48)28(19(3)41)39-30(45)24(35)15-22-10-12-23(43)13-11-22/h5-13,18-20,24-26,28-29,41-43H,14-17,35H2,1-4H3,(H,36,48)(H,37,44)(H,38,46)(H,39,45)(H,40,47)(H,49,50)/t19-,20-,24+,25+,26+,28-,29+/m1/s1 WJEFCEUSQYDJIF-XEAMQDCRSA-N 50018723 2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-3-hydroxy-butyrylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-3-hydroxy-butyric acid::CHEMBL127378 Mu-type opioid receptor Cavia cutleri 460 ChEMBL 10.1021/jm00397a019 10.7270/Q21R6R37 2828622 Gacel, G; Zajac, JM; Delay-Goyet, P; Dauge, V; Roques, BP University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018723 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018723&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10055515 103929800 CHEMBL127378 ZINC27304108 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031488 CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](CO)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C35H50N6O9/c1-20(2)14-26(33(47)40-28(35(49)50)15-21(3)4)39-34(48)27(17-22-8-6-5-7-9-22)38-30(44)18-37-32(46)29(19-42)41-31(45)25(36)16-23-10-12-24(43)13-11-23/h5-13,20-21,25-29,42-43H,14-19,36H2,1-4H3,(H,37,46)(H,38,44)(H,39,48)(H,40,47)(H,41,45)(H,49,50)/t25-,26-,27-,28-,29+/m0/s1 ZZMBQSFEUXQYEQ-MYHRABSESA-N 50018711 2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-3-hydroxy-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-4-methyl-pentanoic acid::CHEMBL338307 Mu-type opioid receptor Cavia cutleri 257 ChEMBL 10.1021/jm00397a019 10.7270/Q21R6R37 2828622 Gacel, G; Zajac, JM; Delay-Goyet, P; Dauge, V; Roques, BP University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018711 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018711&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14019928 103929788 CHEMBL338307 C06396 ZINC27299214 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031489 CC(C)C[C@@H](N[C@@H]([C@@H](C)O)C(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](CO)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C32H46N6O9/c1-18(2)13-26(37-28(19(3)40)32(46)47)38-31(45)24(15-20-7-5-4-6-8-20)35-27(42)16-34-30(44)25(17-39)36-29(43)23(33)14-21-9-11-22(41)12-10-21/h4-12,18-19,23-26,28,37,39-41H,13-17,33H2,1-3H3,(H,34,44)(H,35,42)(H,36,43)(H,38,45)(H,46,47)/t19-,23+,24+,25-,26+,28+/m1/s1 COMSUSZOOWOYPV-PTKQQPMTSA-N 50018717 2-{1-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-3-hydroxy-propionylamino}-acetylamino)-3-phenyl-propionylamino]-3-methyl-butylamino}-3-hydroxy-butyric acid::CHEMBL125060 Mu-type opioid receptor Cavia cutleri 64 ChEMBL 10.1021/jm00397a019 10.7270/Q21R6R37 2828622 Gacel, G; Zajac, JM; Delay-Goyet, P; Dauge, V; Roques, BP University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018717 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018717&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44349525 103929794 CHEMBL125060 C06396 ZINC27210091 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031490 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](CO)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H]([C@@H](C)O)C(O)=O InChI=1S/C33H46N6O10/c1-18(2)13-24(32(47)39-28(19(3)41)33(48)49)37-31(46)25(15-20-7-5-4-6-8-20)36-27(43)16-35-30(45)26(17-40)38-29(44)23(34)14-21-9-11-22(42)12-10-21/h4-12,18-19,23-26,28,40-42H,13-17,34H2,1-3H3,(H,35,45)(H,36,43)(H,37,46)(H,38,44)(H,39,47)(H,48,49)/t19-,23+,24+,25+,26-,28+/m1/s1 PKSODCLCMBUCPW-LVNBQDLPSA-N 50018708 2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-3-hydroxy-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-3-hydroxy-butyric acid::CHEMBL124283::DSLET::DSLET-OH::Tyr-D-Ser-Gly-Phe-Leu-Thr Mu-type opioid receptor Cavia cutleri 406 ChEMBL 10.1021/jm00397a019 10.7270/Q21R6R37 2828622 Gacel, G; Zajac, JM; Delay-Goyet, P; Dauge, V; Roques, BP University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018708 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018708&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 107847 103929785 CHEMBL124283 1609 C06396 ZINC27215004 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031491 CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23-,24-/m0/s1 MCMMCRYPQBNCPH-DVKRWUGUSA-N 50001683 13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid::7-Benzyl-10-{[3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL294616::DPDPE Mu-type opioid receptor Cavia cutleri 10000 ChEMBL 10.1021/jm00397a019 10.7270/Q21R6R37 2828622 Gacel, G; Zajac, JM; Delay-Goyet, P; Dauge, V; Roques, BP University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001683&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299404 103916113 CHEMBL294616 ZINC27520031 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031492 CC(C)CC(C)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C20H32N4O4/c1-12(2)9-13(3)23-18(26)11-22-19(27)14(4)24-20(28)17(21)10-15-5-7-16(25)8-6-15/h5-8,12-14,17,25H,9-11,21H2,1-4H3,(H,22,27)(H,23,26)(H,24,28)/t13?,14-,17+/m1/s1 PUZQCAIXBLYSBU-ROFXEPAZSA-N 50018721 2-Amino-N-(1-{[(1,3-dimethyl-butylcarbamoyl)-methyl]-carbamoyl}-ethyl)-3-(4-hydroxy-phenyl)-propionamide::CHEMBL419414 Mu-type opioid receptor Cavia cutleri 237 ChEMBL 10.1021/jm00397a019 10.7270/Q21R6R37 2828622 Gacel, G; Zajac, JM; Delay-Goyet, P; Dauge, V; Roques, BP University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018721 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018721&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44349910 103929798 CHEMBL419414 ZINC27213627 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031493 CSCC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccccc1)C(O)=O InChI=1S/C27H35N5O7S/c1-40-12-11-21(27(38)39)32-26(37)22(14-18-7-9-19(33)10-8-18)31-24(35)16-29-23(34)15-30-25(36)20(28)13-17-5-3-2-4-6-17/h2-10,20-22,33H,11-16,28H2,1H3,(H,29,34)(H,30,36)(H,31,35)(H,32,37)(H,38,39)/t20-,21-,22-/m0/s1 KSPMUEPUBHARAV-FKBYEOEOSA-N 50018724 2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::CHEMBL339020 Mu-type opioid receptor Cavia cutleri 200 ChEMBL 10.1021/jm00397a019 10.7270/Q21R6R37 2828622 Gacel, G; Zajac, JM; Delay-Goyet, P; Dauge, V; Roques, BP University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018724 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018724&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44349544 103929801 CHEMBL339020 ZINC27209581 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031494 CSCC[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)NCCC(C)C InChI=1S/C21H34N4O4S/c1-14(2)8-10-23-19(27)13-24-21(29)18(9-11-30-3)25-20(28)17(22)12-15-4-6-16(26)7-5-15/h4-7,14,17-18,26H,8-13,22H2,1-3H3,(H,23,27)(H,24,29)(H,25,28)/t17-,18+/m0/s1 MNCXVLXVHKSGGP-ZWKOTPCHSA-N 50018725 2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-N-[(3-methyl-butylcarbamoyl)-methyl]-4-methylsulfanyl-butyramide::CHEMBL338773 Mu-type opioid receptor Cavia cutleri 154 ChEMBL 10.1021/jm00397a019 10.7270/Q21R6R37 2828622 Gacel, G; Zajac, JM; Delay-Goyet, P; Dauge, V; Roques, BP University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018725 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018725&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14019914 103929802 CHEMBL338773 ZINC27212177 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031495 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 70 ChEMBL 10.1021/jm00397a019 10.7270/Q21R6R37 2828622 Gacel, G; Zajac, JM; Delay-Goyet, P; Dauge, V; Roques, BP University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031496 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)[C@H](C)O)C(=O)N1C[C@H](O)C[C@H]1C(O)=O InChI=1S/C35H48N6O10/c1-19(2)13-27(34(49)41-18-24(44)16-28(41)35(50)51)39-32(47)26(15-21-7-5-4-6-8-21)38-29(45)17-37-33(48)30(20(3)42)40-31(46)25(36)14-22-9-11-23(43)12-10-22/h4-12,19-20,24-28,30,42-44H,13-18,36H2,1-3H3,(H,37,48)(H,38,45)(H,39,47)(H,40,46)(H,50,51)/t20-,24+,25-,26-,27-,28-,30+/m0/s1 CTQBZZOOOPNMNB-RKIDTLIPSA-N 50018720 1-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-3-hydroxy-butyrylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoyl}-3-hydroxy-pyrrolidine-2-carboxylic acid::CHEMBL2370602 Mu-type opioid receptor Cavia cutleri 88 ChEMBL 10.1021/jm00397a019 10.7270/Q21R6R37 2828622 Gacel, G; Zajac, JM; Delay-Goyet, P; Dauge, V; Roques, BP University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018720 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018720&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73353055 103929797 CHEMBL2370602 ZINC27210082 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031497 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)NNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H]([C@@H](C)O)C(O)=O InChI=1S/C31H43N7O9/c1-17(2)13-23(29(44)36-26(18(3)39)30(45)46)35-28(43)24(15-19-7-5-4-6-8-19)34-25(41)16-33-31(47)38-37-27(42)22(32)14-20-9-11-21(40)12-10-20/h4-12,17-18,22-24,26,39-40H,13-16,32H2,1-3H3,(H,34,41)(H,35,43)(H,36,44)(H,37,42)(H,45,46)(H2,33,38,47)/t18-,22+,23+,24+,26+/m1/s1 YGFUILXJHYIEQF-ODEHXSTASA-N 50018710 2-(1-{1-[1-amino-2-(4-hydroxyphenyl)ethylcarboxamidoazacarboxamidomethylcarboxamido]-2-phenylethylcarboxamido}-3-methylbutylcarboxamido)-3-hydroxybutanoic acid::CHEMBL333064 Mu-type opioid receptor Cavia cutleri 14000 ChEMBL 10.1021/jm00397a019 10.7270/Q21R6R37 2828622 Gacel, G; Zajac, JM; Delay-Goyet, P; Dauge, V; Roques, BP University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018710 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018710&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14020007 103929787 CHEMBL333064 ZINC27214941 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031498 CC(C)CC(C)NC(=O)CNC(=O)[C@@H](COC(C)(C)C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C24H40N4O5/c1-15(2)11-16(3)27-21(30)13-26-23(32)20(14-33-24(4,5)6)28-22(31)19(25)12-17-7-9-18(29)10-8-17/h7-10,15-16,19-20,29H,11-14,25H2,1-6H3,(H,26,32)(H,27,30)(H,28,31)/t16?,19-,20+/m0/s1 PDXVJTHNKZZZIA-KHMGXFTDSA-N 50018709 2-Amino-N-(2-tert-butoxy-1-{[(1,3-dimethyl-butylcarbamoyl)-methyl]-carbamoyl}-ethyl)-3-(4-hydroxy-phenyl)-propionamide::CHEMBL2370600 Mu-type opioid receptor Cavia cutleri 111 ChEMBL 10.1021/jm00397a019 10.7270/Q21R6R37 2828622 Gacel, G; Zajac, JM; Delay-Goyet, P; Dauge, V; Roques, BP University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018709 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018709&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14019901 103929786 CHEMBL2370600 ZINC27300856 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031499 CC(C)C[C@H](N(C)C(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCCO InChI=1S/C23H37N5O6/c1-14(2)11-19(23(34)25-9-10-29)28(4)20(31)13-26-21(32)15(3)27-22(33)18(24)12-16-5-7-17(30)8-6-16/h5-8,14-15,18-19,29-30H,9-13,24H2,1-4H3,(H,25,34)(H,26,32)(H,27,33)/t15-,18+,19+/m1/s1 VUGAWSMBDUQEPR-MNEFBYGVSA-N 50018714 2-[(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-acetyl)-methyl-amino]-4-methyl-pentanoic acid (2-hydroxy-ethyl)-amide::CHEMBL341500 Mu-type opioid receptor Cavia cutleri 379 ChEMBL 10.1021/jm00397a019 10.7270/Q21R6R37 2828622 Gacel, G; Zajac, JM; Delay-Goyet, P; Dauge, V; Roques, BP University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018714 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018714&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14019922 103929791 CHEMBL341500 C04080 ZINC27209360 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031500 CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)[C@@H](C)O)C(O)=O InChI=1S/C36H52N6O9/c1-20(2)15-27(33(47)41-29(36(50)51)16-21(3)4)40-34(48)28(18-23-9-7-6-8-10-23)39-30(45)19-38-35(49)31(22(5)43)42-32(46)26(37)17-24-11-13-25(44)14-12-24/h6-14,20-22,26-29,31,43-44H,15-19,37H2,1-5H3,(H,38,49)(H,39,45)(H,40,48)(H,41,47)(H,42,46)(H,50,51)/t22-,26+,27+,28+,29+,31-/m1/s1 LMZKZNPWWIWFRK-XQOKKZIDSA-N 50018713 2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-3-hydroxy-butyrylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-4-methyl-pentanoic acid::CHEMBL127711 Mu-type opioid receptor Cavia cutleri 260 ChEMBL 10.1021/jm00397a019 10.7270/Q21R6R37 2828622 Gacel, G; Zajac, JM; Delay-Goyet, P; Dauge, V; Roques, BP University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018713 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018713&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14019978 103929790 CHEMBL127711 ZINC27299713 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031501 CC[C@H](O)[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(O)=O InChI=1S/C35H50N6O10/c1-5-27(44)30(41-31(46)24(36)16-22-11-13-23(43)14-12-22)34(49)37-18-28(45)38-26(17-21-9-7-6-8-10-21)32(47)39-25(15-19(2)3)33(48)40-29(20(4)42)35(50)51/h6-14,19-20,24-27,29-30,42-44H,5,15-18,36H2,1-4H3,(H,37,49)(H,38,45)(H,39,47)(H,40,48)(H,41,46)(H,50,51)/t20-,24+,25+,26+,27+,29+,30+/m1/s1 CBPOZLIYAVCTOE-QQMZDXHTSA-N 50018707 2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-3-hydroxy-pentanoylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-3-hydroxy-butyric acid::CHEMBL2370601 Mu-type opioid receptor Cavia cutleri 21 ChEMBL 10.1021/jm00397a019 10.7270/Q21R6R37 2828622 Gacel, G; Zajac, JM; Delay-Goyet, P; Dauge, V; Roques, BP University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018707 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018707&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73354579 103929784 CHEMBL2370601 ZINC27208395 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031502 CCN(C(C)CC(C)C)C(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C22H36N4O4/c1-6-26(15(4)11-14(2)3)20(28)13-24-21(29)16(5)25-22(30)19(23)12-17-7-9-18(27)10-8-17/h7-10,14-16,19,27H,6,11-13,23H2,1-5H3,(H,24,29)(H,25,30)/t15?,16-,19+/m1/s1 JQXKDUIMUFQTCD-KSBCIKQNSA-N 50018716 2-Amino-N-[1-({[(1,3-dimethyl-butyl)-ethyl-carbamoyl]-methyl}-carbamoyl)-ethyl]-3-(4-hydroxy-phenyl)-propionamide::CHEMBL123631 Mu-type opioid receptor Cavia cutleri 216 ChEMBL 10.1021/jm00397a019 10.7270/Q21R6R37 2828622 Gacel, G; Zajac, JM; Delay-Goyet, P; Dauge, V; Roques, BP University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018716 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018716&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14019907 103929793 CHEMBL123631 ZINC27213225 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031503 CC(C)CC(C)NC(=O)CNC(=O)[C@@H](CO)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C20H32N4O5/c1-12(2)8-13(3)23-18(27)10-22-20(29)17(11-25)24-19(28)16(21)9-14-4-6-15(26)7-5-14/h4-7,12-13,16-17,25-26H,8-11,21H2,1-3H3,(H,22,29)(H,23,27)(H,24,28)/t13?,16-,17+/m0/s1 ASQQCHZPNVTTRH-ZMKYACIDSA-N 50018722 2-Amino-N-(1-{[(1,3-dimethyl-butylcarbamoyl)-methyl]-carbamoyl}-2-hydroxy-ethyl)-3-(4-hydroxy-phenyl)-propionamide::CHEMBL2370599 Mu-type opioid receptor Cavia cutleri 718 ChEMBL 10.1021/jm00397a019 10.7270/Q21R6R37 2828622 Gacel, G; Zajac, JM; Delay-Goyet, P; Dauge, V; Roques, BP University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018722 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018722&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14019899 103929799 CHEMBL2370599 C06396 ZINC27213218 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031504 CC(C)CC(C)NC(=O)CNC(=O)C(C)(C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C21H34N4O4/c1-13(2)10-14(3)24-18(27)12-23-20(29)21(4,5)25-19(28)17(22)11-15-6-8-16(26)9-7-15/h6-9,13-14,17,26H,10-12,22H2,1-5H3,(H,23,29)(H,24,27)(H,25,28)/t14?,17-/m0/s1 MWXMSVBJVUWPSB-JRZJBTRGSA-N 50018718 2-Amino-N-(1-{[(1,3-dimethyl-butylcarbamoyl)-methyl]-carbamoyl}-1-methyl-ethyl)-3-(4-hydroxy-phenyl)-propionamide::CHEMBL339002 Mu-type opioid receptor Cavia cutleri 1850 ChEMBL 10.1021/jm00397a019 10.7270/Q21R6R37 2828622 Gacel, G; Zajac, JM; Delay-Goyet, P; Dauge, V; Roques, BP University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018718 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018718&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14019893 103929795 CHEMBL339002 ZINC27213823 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031505 CC(C)CCNC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C19H30N4O4/c1-12(2)8-9-21-17(25)11-22-18(26)13(3)23-19(27)16(20)10-14-4-6-15(24)7-5-14/h4-7,12-13,16,24H,8-11,20H2,1-3H3,(H,21,25)(H,22,26)(H,23,27)/t13-,16+/m1/s1 NFHMVLYHHDKJEK-CJNGLKHVSA-N 50018719 2-Amino-3-(4-hydroxy-phenyl)-N-(1-{[(3-methyl-butylcarbamoyl)-methyl]-carbamoyl}-ethyl)-propionamide::CHEMBL275050 Mu-type opioid receptor Cavia cutleri 323 ChEMBL 10.1021/jm00397a019 10.7270/Q21R6R37 2828622 Gacel, G; Zajac, JM; Delay-Goyet, P; Dauge, V; Roques, BP University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018719 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018719&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10407310 103929796 CHEMBL275050 ZINC38141702 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031506 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C)[C@@H](Cc1ccccc1)C(=O)NCCO InChI=1S/C26H35N5O6/c1-17(30-25(36)21(27)14-19-8-10-20(33)11-9-19)24(35)29-16-23(34)31(2)22(26(37)28-12-13-32)15-18-6-4-3-5-7-18/h3-11,17,21-22,32-33H,12-16,27H2,1-2H3,(H,28,37)(H,29,35)(H,30,36)/t17-,21+,22+/m1/s1 HPZJMUBDEAMBFI-WTNAPCKOSA-N 21015 (2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]-N-methylacetamido}-N-(2-hydroxyethyl)-3-phenylpropanamide::2-Ala-4-MePhe-5-Gly-Enkephalin::CHEMBL38874::D-Ala2-MePhe4-Met(0)5-enkephalin-ol::DAMGO::RX 783006::US11492374, ID 2::[3H]DAMGO::[tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephalin Mu-type opioid receptor Cavia cutleri 12 ChEMBL 10.1021/jm00397a019 10.7270/Q21R6R37 2828622 Gacel, G; Zajac, JM; Delay-Goyet, P; Dauge, V; Roques, BP University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21015&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5462471 49689088 CHEMBL38874 1647 C04080 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031507 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)[C@@H](C)O)C(=O)N[C@@H](CO)C(O)=O InChI=1S/C33H46N6O10/c1-18(2)13-24(30(45)38-26(17-40)33(48)49)37-31(46)25(15-20-7-5-4-6-8-20)36-27(43)16-35-32(47)28(19(3)41)39-29(44)23(34)14-21-9-11-22(42)12-10-21/h4-12,18-19,23-26,28,40-42H,13-17,34H2,1-3H3,(H,35,47)(H,36,43)(H,37,46)(H,38,45)(H,39,44)(H,48,49)/t19-,23+,24+,25+,26+,28-/m1/s1 PNBNSLOJUXPNIY-PWRRRBSQSA-N 50018715 2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-3-hydroxy-butyrylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-3-hydroxy-propionic acid::CHEMBL125564 Mu-type opioid receptor Cavia cutleri 99 ChEMBL 10.1021/jm00397a019 10.7270/Q21R6R37 2828622 Gacel, G; Zajac, JM; Delay-Goyet, P; Dauge, V; Roques, BP University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018715 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018715&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14019974 103929792 CHEMBL125564 ZINC27210087 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031508 CC(C)C[C@H](N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)[C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O InChI=1S/C35H50N6O10/c1-19(2)15-27(32(47)40-30(21(4)43)35(50)51)41(5)34(49)26(17-22-9-7-6-8-10-22)38-28(45)18-37-33(48)29(20(3)42)39-31(46)25(36)16-23-11-13-24(44)14-12-23/h6-14,19-21,25-27,29-30,42-44H,15-18,36H2,1-5H3,(H,37,48)(H,38,45)(H,39,46)(H,40,47)(H,50,51)/t20-,21-,25+,26+,27+,29-,30+/m1/s1 OGDLYBQGTPBSRO-ZISJZQMRSA-N 50018726 2-(2-{[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-3-hydroxy-butyrylamino}-acetylamino)-3-phenyl-propionyl]-methyl-amino}-4-methyl-pentanoylamino)-3-hydroxy-butyric acid::CHEMBL341480 Mu-type opioid receptor Cavia cutleri 224 ChEMBL 10.1021/jm00397a019 10.7270/Q21R6R37 2828622 Gacel, G; Zajac, JM; Delay-Goyet, P; Dauge, V; Roques, BP University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018726 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018726&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14019966 103929803 CHEMBL341480 ZINC27304311 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031510 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)N(C)C(=O)[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)[C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O InChI=1S/C33H47N5O9/c1-18(2)15-25(30(43)37-28(20(4)40)33(46)47)35-31(44)26(17-21-9-7-6-8-10-21)38(5)32(45)27(19(3)39)36-29(42)24(34)16-22-11-13-23(41)14-12-22/h6-14,18-20,24-28,39-41H,15-17,34H2,1-5H3,(H,35,44)(H,36,42)(H,37,43)(H,46,47)/t19-,20-,24+,25+,26+,27-,28+/m1/s1 PWCNFAODFZLYFO-PDZRYRBSSA-N 50018727 2-{2-[2-({2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-3-hydroxy-butyryl}-methyl-amino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-3-hydroxy-butyric acid::CHEMBL338661 Mu-type opioid receptor Cavia cutleri 93 ChEMBL 10.1021/jm00397a019 10.7270/Q21R6R37 2828622 Gacel, G; Zajac, JM; Delay-Goyet, P; Dauge, V; Roques, BP University of Paris http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018727 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018727&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44349523 103929804 CHEMBL338661 ZINC27210074 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50030371 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1 DQCKKXVULJGBQN-XFWGSAIBSA-N 60212 (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::MLS000069607::NALTREXONE HYDROCHLORIDE::SMR000058767::US10988481, Compound NTX::US9107954, naltrexone::cid_5485201 Mu-type opioid receptor Cavia cutleri 0.370000 ChEMBL 10.1021/jm00157a018 10.7270/Q2M04606 2879914 Lipkowski, AW; Tam, SW; Portoghese, PS TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60212&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5360515 252639834 DB00704 C07253 ZINC00001773 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50027296 CN1[C@@H](Cc2ccccc2)C(=O)N[C@@H](CC(=O)NCCC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C1=O)C(N)=O InChI=1S/C28H36N6O6/c1-34-23(15-17-6-3-2-4-7-17)27(39)33-22(25(30)37)16-24(36)31-13-5-8-21(28(34)40)32-26(38)20(29)14-18-9-11-19(35)12-10-18/h2-4,6-7,9-12,20-23,35H,5,8,13-16,29H2,1H3,(H2,30,37)(H,31,36)(H,32,38)(H,33,39)/t20-,21+,22-,23-/m0/s1 VOICTBLLXAGMMO-BJESRGMDSA-N 50018636 12-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-2-benzyl-1-methyl-3,7,13-trioxo-1,4,8triaza-cyclotridecane-5-carboxylic acid amide::CHEMBL304431 Mu-type opioid receptor Cavia cutleri 6460 ChEMBL 10.1021/jm00394a027 10.7270/Q2416W24 2822930 Schiller, PW; Nguyen, TM; Maziak, LA; Wilkes, BC; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018636&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44306484 103929728 CHEMBL304431 ZINC26181454 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50027297 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CCCNC(=O)C[C@@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(N)=O InChI=1S/C27H34N6O6/c28-19(13-17-8-10-18(34)11-9-17)25(37)31-20-7-4-12-30-23(35)15-21(24(29)36)32-27(39)22(33-26(20)38)14-16-5-2-1-3-6-16/h1-3,5-6,8-11,19-22,34H,4,7,12-15,28H2,(H2,29,36)(H,30,35)(H,31,37)(H,32,39)(H,33,38)/t19-,20+,21+,22-/m0/s1 HNDAPGXWFDLKOJ-CBPXPLCBSA-N 50018635 12-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-2-benzyl-3,7,13-trioxo-1,4,8triaza-cyclotridecane-5-carboxylic acid amide::CHEMBL303513 Mu-type opioid receptor Cavia cutleri 632 ChEMBL 10.1021/jm00394a027 10.7270/Q2416W24 2822930 Schiller, PW; Nguyen, TM; Maziak, LA; Wilkes, BC; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018635 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018635&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44306222 103929727 CHEMBL303513 ZINC26183349 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50027299 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CCCNC(=O)C[C@H](NC(=O)[C@@H](NC1=O)C1CCCCC1)C(N)=O InChI=1S/C26H38N6O6/c27-18(13-15-8-10-17(33)11-9-15)24(36)30-19-7-4-12-29-21(34)14-20(23(28)35)31-26(38)22(32-25(19)37)16-5-2-1-3-6-16/h8-11,16,18-20,22,33H,1-7,12-14,27H2,(H2,28,35)(H,29,34)(H,30,36)(H,31,38)(H,32,37)/t18-,19+,20-,22-/m0/s1 NWGQJLUMVGAMDN-IIZPIQPGSA-N 50018633 12-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-2-cyclohexyl-3,7,13-trioxo-1,4,8triaza-cyclotridecane-5-carboxylic acid amide::CHEMBL66039 Mu-type opioid receptor Cavia cutleri 18400 ChEMBL 10.1021/jm00394a027 10.7270/Q2416W24 2822930 Schiller, PW; Nguyen, TM; Maziak, LA; Wilkes, BC; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018633 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018633&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44306223 103929725 CHEMBL66039 ZINC26183353 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50027300 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CCCNC(=O)C[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(N)=O InChI=1S/C27H34N6O6/c28-19(13-17-8-10-18(34)11-9-17)25(37)31-20-7-4-12-30-23(35)15-21(24(29)36)32-27(39)22(33-26(20)38)14-16-5-2-1-3-6-16/h1-3,5-6,8-11,19-22,34H,4,7,12-15,28H2,(H2,29,36)(H,30,35)(H,31,37)(H,32,39)(H,33,38)/t19-,20+,21-,22-/m0/s1 HNDAPGXWFDLKOJ-LRSLUSHPSA-N 50001467 12-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-2-benzyl-3,7,13-trioxo-1,4,8triaza-cyclotridecane-5-carboxylic acid amide::CHEMBL63407 Mu-type opioid receptor Cavia cutleri 36 ChEMBL 10.1021/jm00394a027 10.7270/Q2416W24 2822930 Schiller, PW; Nguyen, TM; Maziak, LA; Wilkes, BC; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001467&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 125942 103915932 CHEMBL63407 ZINC26181761 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50027308 CC(C)C[C@@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C28H37N5O7/c1-17(2)12-23(28(39)40)33-27(38)22(14-18-6-4-3-5-7-18)32-25(36)16-30-24(35)15-31-26(37)21(29)13-19-8-10-20(34)11-9-19/h3-11,17,21-23,34H,12-16,29H2,1-2H3,(H,30,35)(H,31,37)(H,32,36)(H,33,38)(H,39,40)/t21-,22-,23-/m1/s1 URLZCHNOLZSCCA-DNVJHFABSA-N 50007329 (R)-2-[(R)-2-(2-{2-[(R)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::(all-D-[Leu]-enkephalin)2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::CHEMBL15595::[Leu5] enkephalin Mu-type opioid receptor Cavia cutleri 246 ChEMBL 10.1021/jm00394a027 10.7270/Q2416W24 2822930 Schiller, PW; Nguyen, TM; Maziak, LA; Wilkes, BC; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007329 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007329&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10415290 103920604 CHEMBL15595 ZINC53147460 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50027311 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CCCNC(=O)C[C@H](NC(=O)[C@H](Cc2ccc(cc2)[N+]([O-])=O)NC1=O)C(N)=O InChI=1S/C27H33N7O8/c28-19(12-15-5-9-18(35)10-6-15)25(38)31-20-2-1-11-30-23(36)14-21(24(29)37)32-27(40)22(33-26(20)39)13-16-3-7-17(8-4-16)34(41)42/h3-10,19-22,35H,1-2,11-14,28H2,(H2,29,37)(H,30,36)(H,31,38)(H,32,40)(H,33,39)/t19-,20+,21-,22-/m0/s1 YHLQBUMFTKANHO-LRSLUSHPSA-N 50018638 12-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-2-(4-nitro-benzyl)-3,7,13-trioxo-1,4,8triaza-cyclotridecane-5-carboxylic acid amide::CHEMBL303418 Mu-type opioid receptor Cavia cutleri 2340 ChEMBL 10.1021/jm00394a027 10.7270/Q2416W24 2822930 Schiller, PW; Nguyen, TM; Maziak, LA; Wilkes, BC; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018638&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44306727 103929730 CHEMBL303418 ZINC26250288 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50027312 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CCCNC(=O)C[C@H](NC(=O)[C@@H](Cc2ccccc2)NC1=O)C(N)=O InChI=1S/C27H34N6O6/c28-19(13-17-8-10-18(34)11-9-17)25(37)31-20-7-4-12-30-23(35)15-21(24(29)36)32-27(39)22(33-26(20)38)14-16-5-2-1-3-6-16/h1-3,5-6,8-11,19-22,34H,4,7,12-15,28H2,(H2,29,36)(H,30,35)(H,31,37)(H,32,39)(H,33,38)/t19-,20+,21-,22+/m0/s1 HNDAPGXWFDLKOJ-LNRXMEIDSA-N 50018632 12-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-2-benzyl-3,7,13-trioxo-1,4,8triaza-cyclotridecane-5-carboxylic acid amide::CHEMBL63972 Mu-type opioid receptor Cavia cutleri >21000 ChEMBL 10.1021/jm00394a027 10.7270/Q2416W24 2822930 Schiller, PW; Nguyen, TM; Maziak, LA; Wilkes, BC; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018632 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018632&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44306356 103929724 CHEMBL63972 ZINC26183950 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50027319 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CC(=O)NCCC[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(N)=O InChI=1S/C27H34N6O6/c28-19(13-17-8-10-18(34)11-9-17)25(37)32-22-15-23(35)30-12-4-7-20(24(29)36)31-26(38)21(33-27(22)39)14-16-5-2-1-3-6-16/h1-3,5-6,8-11,19-22,34H,4,7,12-15,28H2,(H2,29,36)(H,30,35)(H,31,38)(H,32,37)(H,33,39)/t19-,20-,21-,22+/m0/s1 RAYNTFITBYGTEZ-MYGLTJDJSA-N 50018637 12-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-2-benzyl-3,10,13-trioxo-1,4,9triaza-cyclotridecane-5-carboxylic acid amide::CHEMBL68177 Mu-type opioid receptor Cavia cutleri 522 ChEMBL 10.1021/jm00394a027 10.7270/Q2416W24 2822930 Schiller, PW; Nguyen, TM; Maziak, LA; Wilkes, BC; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018637&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44306726 103929729 CHEMBL68177 ZINC26250282 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50027323 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CCCNC(=O)C[C@H](NC(=O)[C@H](CCc2ccccc2)NC1=O)C(N)=O InChI=1S/C28H36N6O6/c29-20(15-18-8-11-19(35)12-9-18)26(38)32-21-7-4-14-31-24(36)16-23(25(30)37)34-28(40)22(33-27(21)39)13-10-17-5-2-1-3-6-17/h1-3,5-6,8-9,11-12,20-23,35H,4,7,10,13-16,29H2,(H2,30,37)(H,31,36)(H,32,38)(H,33,39)(H,34,40)/t20-,21+,22-,23-/m0/s1 UCNKQZQIXSIGBL-BJESRGMDSA-N 50018631 12-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-3,7,13-trioxo-2-phenethyl-1,4,8triaza-cyclotridecane-5-carboxylic acid amide::CHEMBL65047 Mu-type opioid receptor Cavia cutleri 111 ChEMBL 10.1021/jm00394a027 10.7270/Q2416W24 2822930 Schiller, PW; Nguyen, TM; Maziak, LA; Wilkes, BC; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018631 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018631&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44306355 103929723 CHEMBL65047 ZINC26183945 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50027324 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CC(=O)NCC[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(N)=O InChI=1S/C26H32N6O6/c27-18(12-16-6-8-17(33)9-7-16)24(36)31-21-14-22(34)29-11-10-19(23(28)35)30-25(37)20(32-26(21)38)13-15-4-2-1-3-5-15/h1-9,18-21,33H,10-14,27H2,(H2,28,35)(H,29,34)(H,30,37)(H,31,36)(H,32,38)/t18-,19-,20-,21+/m0/s1 WCYSVYGPAPZADV-XSDIEEQYSA-N 50018639 11-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-2-benzyl-3,9,12-trioxo-1,4,8triaza-cyclododecane-5-carboxylic acid amide::CHEMBL63235 Mu-type opioid receptor Cavia cutleri 279 ChEMBL 10.1021/jm00394a027 10.7270/Q2416W24 2822930 Schiller, PW; Nguyen, TM; Maziak, LA; Wilkes, BC; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018639&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44306508 103929731 CHEMBL63235 ZINC26183730 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50027328 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(N)=O InChI=1S/C24H29N5O5S2/c25-17(10-15-6-8-16(30)9-7-15)22(32)29-20-13-36-35-12-19(21(26)31)28-23(33)18(27-24(20)34)11-14-4-2-1-3-5-14/h1-9,17-20,30H,10-13,25H2,(H2,26,31)(H,27,34)(H,28,33)(H,29,32)/t17-,18-,19-,20+/m0/s1 GWIQBMQXSQTVNB-LWYYNNOASA-N 50018640 10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid amide::CHEMBL302408 Mu-type opioid receptor Cavia cutleri 65 ChEMBL 10.1021/jm00394a027 10.7270/Q2416W24 2822930 Schiller, PW; Nguyen, TM; Maziak, LA; Wilkes, BC; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018640 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018640&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44306509 103929732 CHEMBL302408 ZINC26183735 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50027331 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H]1CCCNC(=O)C[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(N)=O InChI=1S/C27H34N6O6/c28-19(13-17-8-10-18(34)11-9-17)25(37)31-20-7-4-12-30-23(35)15-21(24(29)36)32-27(39)22(33-26(20)38)14-16-5-2-1-3-6-16/h1-3,5-6,8-11,19-22,34H,4,7,12-15,28H2,(H2,29,36)(H,30,35)(H,31,37)(H,32,39)(H,33,38)/t19-,20-,21-,22-/m0/s1 HNDAPGXWFDLKOJ-CMOCDZPBSA-N 50018634 12-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-2-benzyl-3,7,13-trioxo-1,4,8triaza-cyclotridecane-5-carboxylic acid amide::CHEMBL64949 Mu-type opioid receptor Cavia cutleri 16800 ChEMBL 10.1021/jm00394a027 10.7270/Q2416W24 2822930 Schiller, PW; Nguyen, TM; Maziak, LA; Wilkes, BC; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018634&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14444335 103929726 CHEMBL64949 ZINC26179483 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50030578 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](CCC(=O)NCC(=O)NCC(N)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C35H48N8O10/c1-20(2)14-27(35(52)53)43-34(51)26(16-21-6-4-3-5-7-21)41-31(48)19-40-33(50)25(12-13-29(46)39-18-30(47)38-17-28(37)45)42-32(49)24(36)15-22-8-10-23(44)11-9-22/h3-11,20,24-27,44H,12-19,36H2,1-2H3,(H2,37,45)(H,38,47)(H,39,46)(H,40,50)(H,41,48)(H,42,49)(H,43,51)(H,52,53)/t24-,25-,26-,27-/m0/s1 KKXZNPZWFWSTFC-FWEHEUNISA-N 50016458 2-{2-[2-(2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-4-{[(carbamoylmethyl-carbamoyl)-methyl]-carbamoyl}-butyrylamino)-acetylamino]-3-phenyl-propionylamino}-4-methyl-pentanoic acid::CHEMBL60377 Mu-type opioid receptor Cavia cutleri 53 ChEMBL 10.1021/jm00394a010 10.7270/Q24T6JZK 2444704 Portoghese, PS; Larson, DL; Ronsisvalle, G; Schiller, PW; Nguyen, TM; Lemieux, C; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016458&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44302743 103927870 CHEMBL60377 C03636 ZINC26158586 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50030579 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C31H42N6O8/c1-18(2)14-25(31(44)45)37-30(43)24(16-19-6-4-3-5-7-19)35-27(40)17-34-29(42)23(12-13-26(33)39)36-28(41)22(32)15-20-8-10-21(38)11-9-20/h3-11,18,22-25,38H,12-17,32H2,1-2H3,(H2,33,39)(H,34,42)(H,35,40)(H,36,41)(H,37,43)(H,44,45)/t22-,23-,24-,25-/m0/s1 ADRDWKBFXHXFGK-QORCZRPOSA-N 50016459 2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-4-carbamoyl-butyrylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::CHEMBL294134 Mu-type opioid receptor Cavia cutleri 22 ChEMBL 10.1021/jm00394a010 10.7270/Q24T6JZK 2444704 Portoghese, PS; Larson, DL; Ronsisvalle, G; Schiller, PW; Nguyen, TM; Lemieux, C; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016459&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44302918 103927871 CHEMBL294134 ZINC26144216 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50030580 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](CCC(=O)NCC(=O)NCC(=O)N[C@H]1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3C)c45)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C52H67N9O13/c1-28(2)21-37(50(71)72)60-49(70)36(23-29-7-5-4-6-8-29)58-43(67)27-56-48(69)35(59-47(68)33(53)22-30-9-12-32(62)13-10-30)14-16-40(64)54-25-41(65)55-26-42(66)57-34-17-18-52(73)39-24-31-11-15-38(63)45-44(31)51(52,46(34)74-45)19-20-61(39)3/h4-13,15,28,33-37,39,46,62-63,73H,14,16-27,53H2,1-3H3,(H,54,64)(H,55,65)(H,56,69)(H,57,66)(H,58,67)(H,59,68)(H,60,70)(H,71,72)/t33-,34-,35-,36-,37-,39?,46-,51-,52+/m0/s1 NLKULMDQSJKTBS-FIRPBRJLSA-N 50016454 1N-[10,17-dihydroxy-4-methyl-(13R,14S,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-ylcarbamoylmethyl]-2-methylcarboxamidoacetamide-N-N'-2-[1-[1-[1-amino-2-(4-hydroxyphenyl)-(1S)-ethylcarboxamido]-(1S)-ethylcarboxamidomethylcarboxamido]-2-phenyl-(1S)-ethylcarboxamido]-4-methyl-(2S)-pentanoic acid::CID44302742::oxymorphamine- and enkephalin-containing ligand 2 Mu-type opioid receptor Cavia cutleri 11 ChEMBL 10.1021/jm00394a010 10.7270/Q24T6JZK 2444704 Portoghese, PS; Larson, DL; Ronsisvalle, G; Schiller, PW; Nguyen, TM; Lemieux, C; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016454 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016454&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44302742 103927866 C03636 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50030581 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@]3(O)CC[C@@H]4NC(=O)CNC(=O)CNC(C)=O)ccc5O InChI=1S/C23H30N4O6/c1-12(28)24-10-17(30)25-11-18(31)26-14-5-6-23(32)16-9-13-3-4-15(29)20-19(13)22(23,21(14)33-20)7-8-27(16)2/h3-4,14,16,21,29,32H,5-11H2,1-2H3,(H,24,28)(H,25,30)(H,26,31)/t14-,16?,21-,22-,23+/m0/s1 PEAVNOCQOMOSQW-WNFHRKOJSA-N 50016455 1N-[10,17-dihydroxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-ylcarbamoylmethyl]-2-methylcarboxamidoacetamide Mu-type opioid receptor Cavia cutleri 5.5 ChEMBL 10.1021/jm00394a010 10.7270/Q24T6JZK 2444704 Portoghese, PS; Larson, DL; Ronsisvalle, G; Schiller, PW; Nguyen, TM; Lemieux, C; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016455 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016455&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44302897 103927867 ZINC26156084 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50030583 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@]3(O)CC[C@@H]4NC(C)=O)ccc5O InChI=1S/C19H24N2O4/c1-10(22)20-12-5-6-19(24)14-9-11-3-4-13(23)16-15(11)18(19,17(12)25-16)7-8-21(14)2/h3-4,12,14,17,23-24H,5-9H2,1-2H3,(H,20,22)/t12-,14?,17-,18-,19+/m0/s1 WZKKHNQPRSDJFT-UFTKJLKHSA-N 50016457 1N-[10,17-dihydroxy-4-methyl-(13R,14S,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-yl]acetamide::N-[(1S,13R,14S,17S)-10,17-dihydroxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10-trien-14-yl]acetamide Mu-type opioid receptor Cavia cutleri 1.8 ChEMBL 10.1021/jm00394a010 10.7270/Q24T6JZK 2444704 Portoghese, PS; Larson, DL; Ronsisvalle, G; Schiller, PW; Nguyen, TM; Lemieux, C; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016457 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016457&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44302480 103927869 ZINC26143805 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50030584 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](CCC(=O)N[C@H]1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3C)c45)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C48H61N7O11/c1-26(2)21-35(46(63)64)54-45(62)34(23-27-7-5-4-6-8-27)52-39(59)25-50-44(61)33(53-43(60)31(49)22-28-9-12-30(56)13-10-28)14-16-38(58)51-32-17-18-48(65)37-24-29-11-15-36(57)41-40(29)47(48,42(32)66-41)19-20-55(37)3/h4-13,15,26,31-35,37,42,56-57,65H,14,16-25,49H2,1-3H3,(H,50,61)(H,51,58)(H,52,59)(H,53,60)(H,54,62)(H,63,64)/t31-,32-,33-,34-,35-,37?,42-,47-,48+/m0/s1 ZRQRPXGBXCPBLR-UAIOQJEZSA-N 50016456 1N-[10,17-dihydroxy-4-methyl-(13R,14S,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-yl]acetamide-N-N'-[2-[1-[1-[1-amino-2-(4-hydroxyphenyl)-(1S)-ethylcarboxamido]-(1S)-ethylcarboxamidomethylcarboxamido]-2-phenyl-(1S)-ethylcarboxamido]-4-methyl-(2S)-pentanoic acid::CID44302606::oxymorphamine- and enkephalin-containing ligand 1 Mu-type opioid receptor Cavia cutleri 19 ChEMBL 10.1021/jm00394a010 10.7270/Q24T6JZK 2444704 Portoghese, PS; Larson, DL; Ronsisvalle, G; Schiller, PW; Nguyen, TM; Lemieux, C; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016456&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44302606 103927868 C03636 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50030585 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C28H37N5O7/c1-17(2)12-23(28(39)40)33-27(38)22(14-18-6-4-3-5-7-18)32-25(36)16-30-24(35)15-31-26(37)21(29)13-19-8-10-20(34)11-9-19/h3-11,17,21-23,34H,12-16,29H2,1-2H3,(H,30,35)(H,31,37)(H,32,36)(H,33,38)(H,39,40)/t21-,22-,23-/m0/s1 URLZCHNOLZSCCA-VABKMULXSA-N 50001465 (S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::([Leu]-enkephalin)2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::(enkephalin)2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-1-oxo-3-phenyl-propylamino]-4-methyl-pentanoic acid::2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::2-[1-[1-amino-2-(4-hydroxyphenyl)-(1S)-ethylcarboxamidomethylcarboxamidomethylcarboxamido]-2-phenyl-(1S)-ethylcarboxamido]-4-methyl-(2S)-pentanoic acid::2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid(Enkephalin)::2-{1-[1-amino-2-(4-hydroxyphenyl)ethylcarboxamidomethylcarboxamidomethylcarboxamido]-2-phenylethylcarboxamido}-4-methylpentanoic acid::CHEMBL8234::ENKEPHALIN::Leu-ENKEPHALIN::Leu5-Enkephalin::Tyr-Gly-Gly-Phe-Leu-OH Mu-type opioid receptor Cavia cutleri 9.4 ChEMBL 10.1021/jm00394a010 10.7270/Q24T6JZK 2444704 Portoghese, PS; Larson, DL; Ronsisvalle, G; Schiller, PW; Nguyen, TM; Lemieux, C; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001465&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 461776 103915930 CHEMBL8234 ZINC14952116 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50028565 CC(C)C[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C29H39N5O7/c1-17(2)13-24(29(40)41)34-28(39)23(15-19-7-5-4-6-8-19)33-25(36)16-31-26(37)18(3)32-27(38)22(30)14-20-9-11-21(35)12-10-20/h4-12,17-18,22-24,35H,13-16,30H2,1-3H3,(H,31,37)(H,32,38)(H,33,36)(H,34,39)(H,40,41)/t18-,22+,23+,24-/m1/s1 ZHUJMSMQIPIPTF-IBURTVSXSA-N 21025 (2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanamido]-4-methylpentanoic acid::(D-Ala2,D-Leu5)-Enkephalin::BW-180C::CHEMBL340032::DADLE::DADLE-OH::H-Tyr-D-Ala-Gly-Phe-D-Leu-OH::[D-Ala2-D-Leu5]enkephalin Mu-type opioid receptor Cavia cutleri 48 ChEMBL 10.1021/jm00142a002 10.7270/Q2QC0411 6276540 Gacel, G; Fournie-Zaluski, MC; Fellion, E; Roques, BP TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21025&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 6917707 49689098 CHEMBL340032 ZINC14952092 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031602 CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1cccc2occc12 InChI=1S/C21H28N2O2/c1-22(18-8-2-3-9-19(18)23-12-4-5-13-23)21(24)15-16-7-6-10-20-17(16)11-14-25-20/h6-7,10-11,14,18-19H,2-5,8-9,12-13,15H2,1H3/t18-,19-/m1/s1 HTXMQQXQLBZACS-RTBURBONSA-N 50018762 2-Benzofuran-4-yl-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide; hydrobromide, Hydrate::2-Benzofuran-4-yl-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide; hydrochloride::2-Benzofuran-4-yl-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide; hydrochloride, Hydrate::CHEMBL558608 Mu-type opioid receptor Cavia cutleri 1600 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018762&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14040453 103929821 CHEMBL558608 ZINC00003822 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031603 CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1cccc2occc12 InChI=1S/C21H28N2O2/c1-22(18-8-2-3-9-19(18)23-12-4-5-13-23)21(24)15-16-7-6-10-20-17(16)11-14-25-20/h6-7,10-11,14,18-19H,2-5,8-9,12-13,15H2,1H3/t18-,19-/m1/s1 HTXMQQXQLBZACS-RTBURBONSA-N 50018762 2-Benzofuran-4-yl-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide; hydrobromide, Hydrate::2-Benzofuran-4-yl-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide; hydrochloride::2-Benzofuran-4-yl-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide; hydrochloride, Hydrate::CHEMBL558608 Mu-type opioid receptor Cavia cutleri 1600 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018762&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14040453 103929821 CHEMBL558608 ZINC00003822 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031604 CN([C@H]1CCCC[C@@H]1N1CCCC1)C(=O)Cc1cccc2sccc12 InChI=1S/C21H28N2OS/c1-22(18-8-2-3-9-19(18)23-12-4-5-13-23)21(24)15-16-7-6-10-20-17(16)11-14-25-20/h6-7,10-11,14,18-19H,2-5,8-9,12-13,15H2,1H3/t18-,19-/m0/s1 SYHJZCCNQDFHJQ-OALUTQOASA-N 50008854 2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide; hydrochloride::CHEMBL543331 Mu-type opioid receptor Cavia cutleri 1000 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008854&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9906722 103921955 CHEMBL543331 ZINC03779690 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031605 CN([C@H]1CCCC[C@@H]1N1CCCC1)C(=O)Cc1cccc2sccc12 InChI=1S/C21H28N2OS/c1-22(18-8-2-3-9-19(18)23-12-4-5-13-23)21(24)15-16-7-6-10-20-17(16)11-14-25-20/h6-7,10-11,14,18-19H,2-5,8-9,12-13,15H2,1H3/t18-,19-/m0/s1 SYHJZCCNQDFHJQ-OALUTQOASA-N 50008854 2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide; hydrochloride::CHEMBL543331 Mu-type opioid receptor Cavia cutleri 1000 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008854&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9906722 103921955 CHEMBL543331 ZINC03779690 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50029839 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)CCC4=O)ccc5O InChI=1S/C17H19NO4/c1-18-7-6-16-13-9-2-3-10(19)14(13)22-15(16)11(20)4-5-17(16,21)12(18)8-9/h2-3,12,15,19,21H,4-8H2,1H3/t12-,15+,16+,17-/m1/s1 UQCNKQCJZOAFTQ-ISWURRPUSA-N 50001707 10,17-dihydroxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::10,17-dihydroxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(oxymorphone)::10,17-dihydroxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(xymorphone)::10,17-dihydroxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-trien-14-one::CHEMBL963::Codoxy::Combunox::Numorphan::OXYMORPHONE::Opana::Oxycet::PERCODAN-DEMI::Percocet::Percodan::Roxicet::Roxilox::Roxiprin::Tylox::Tylox-325 Mu-type opioid receptor Cavia cutleri 0.780000 ChEMBL 10.1021/jm00145a024 10.7270/Q27W6CSW 2409281 Archer, S; Seyed-Mozaffari, A; Ward, S; Kosterlitz, HW; Paterson, SJ; McKnight, AT; Corbett, AD TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001707 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001707&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5284604 103916122 CHEMBL963 DB01192 7094 C08019 ZINC03875483 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50029841 Oc1ccc2c3c1O[C@H]1C(=O)CC[C@@]4(O)C(N(CC5CC5)CCC314)C2=O InChI=1S/C20H21NO5/c22-12-4-3-11-14-16(12)26-18-13(23)5-6-20(25)17(15(11)24)21(9-10-1-2-10)8-7-19(14,18)20/h3-4,10,17-18,22,25H,1-2,5-9H2/t17?,18-,19?,20+/m0/s1 MLHMRULRADVYER-ZUPWUQBJSA-N 50016086 4-cyclopropylmethyl-10,17-dihydroxy-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-triene-6,14-dione(Ketonaltrexone)::CHEMBL366520 Mu-type opioid receptor Cavia cutleri 31 ChEMBL 10.1021/jm00145a024 10.7270/Q27W6CSW 2409281 Archer, S; Seyed-Mozaffari, A; Ward, S; Kosterlitz, HW; Paterson, SJ; McKnight, AT; Corbett, AD TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016086 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016086&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44385830 103927766 CHEMBL366520 ZINC36221423 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50029842 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1 DQCKKXVULJGBQN-XFWGSAIBSA-N 60212 (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::MLS000069607::NALTREXONE HYDROCHLORIDE::SMR000058767::US10988481, Compound NTX::US9107954, naltrexone::cid_5485201 Mu-type opioid receptor Cavia cutleri 1.1 ChEMBL 10.1021/jm00145a024 10.7270/Q27W6CSW 2409281 Archer, S; Seyed-Mozaffari, A; Ward, S; Kosterlitz, HW; Paterson, SJ; McKnight, AT; Corbett, AD TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60212&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5360515 252639834 DB00704 C07253 ZINC00001773 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50028733 CC1C2Cc3ccc(O)cc3C1(C)CC(C#N)N2C InChI=1S/C16H20N2O/c1-10-15-6-11-4-5-13(19)7-14(11)16(10,2)8-12(9-17)18(15)3/h4-5,7,10,12,15,19H,6,8H2,1-3H3 DDJOYOMHKDFQJK-UHFFFAOYSA-N 50028653 (+)-8-Hydroxy-3,6,11-trimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-4-carbonitrile::(-)-8-Hydroxy-3,6,11-trimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-4-carbonitrile::CHEMBL441776 Mu-type opioid receptor Cavia cutleri 510 ChEMBL 10.1021/jm00354a006 10.7270/Q2NG4R56 7154002 Ramakrishnan, K; Portoghese, PS TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028653 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028653&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44280763 103937857 CHEMBL441776 ZINC38148506 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50028734 CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O InChI=1S/C28H38N6O6S/c1-17(32-27(39)21(29)14-19-8-10-20(35)11-9-19)26(38)31-16-24(36)33-23(15-18-6-4-3-5-7-18)28(40)34-22(25(30)37)12-13-41-2/h3-11,17,21-23,35H,12-16,29H2,1-2H3,(H2,30,37)(H,31,38)(H,32,39)(H,33,36)(H,34,40)/t17-,21+,22+,23+/m1/s1 ANZXICRKKYOVMY-SZOBAZRNSA-N 50304493 CHEMBL595972::Tyr-D-Ala-Gly-Phe-Met-NH2::Tyr-DAla-Gly-Phe-Met-NH2 Mu-type opioid receptor Cavia cutleri 17 ChEMBL 10.1021/jm00354a006 10.7270/Q2NG4R56 7154002 Ramakrishnan, K; Portoghese, PS TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50304493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50304493&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10371120 104158854 CHEMBL595972 ZINC49757425 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50028737 CC(C)C[C@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H](CCCCNC1=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C32H44N6O6.C2H4O2/c1-20(2)16-26-31(43)34-15-7-6-10-25(37-29(41)24(33)17-22-11-13-23(39)14-12-22)30(42)35-19-28(40)36-27(32(44)38-26)18-21-8-4-3-5-9-21;1-2(3)4/h3-5,8-9,11-14,20,24-27,39H,6-7,10,15-19,33H2,1-2H3,(H,34,43)(H,35,42)(H,36,40)(H,37,41)(H,38,44);1H3,(H,3,4)/t24-,25+,26+,27-;/m0./s1 FVBMNJRVPFTJGJ-IHBHCIFXSA-N 50452138 CHEMBL2372196 Mu-type opioid receptor Cavia cutleri 2.4 ChEMBL 10.1021/jm00354a008 10.7270/Q2HQ40G9 6296388 DiMaio, J; Nguyen, TM; Lemieux, C; Schiller, PW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452138 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452138&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73350250 225145587 CHEMBL2372196 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50028738 CC(O)=O.CC[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(N)=O InChI=1S/C30H42N6O6.C2H4O2/c1-4-23(35-28(40)22(31)15-20-10-12-21(37)13-11-20)29(41)33-17-26(38)34-25(16-19-8-6-5-7-9-19)30(42)36-24(27(32)39)14-18(2)3;1-2(3)4/h5-13,18,22-25,37H,4,14-17,31H2,1-3H3,(H2,32,39)(H,33,41)(H,34,38)(H,35,40)(H,36,42);1H3,(H,3,4)/t22-,23+,24-,25-;/m0./s1 IFHVUYVHQNPMQV-DKVOZMMNSA-N 50027505 Acetate1-[1-({[1-(1-carbamoyl-3-methyl-butylcarbamoyl)-2-phenyl-ethylcarbamoyl]-methyl}-carbamoyl)-propylcarbamoyl]-2-(4-hydroxy-phenyl)-ethyl-ammonium;::CHEMBL2372198 Mu-type opioid receptor Cavia cutleri 29 ChEMBL 10.1021/jm00354a008 10.7270/Q2HQ40G9 6296388 DiMaio, J; Nguyen, TM; Lemieux, C; Schiller, PW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027505 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027505&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73354737 103936975 CHEMBL2372198 ZINC36215645 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50028739 CC(O)=O.CC(C)C[C@@H]1NC(=O)[C@@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H](CCNC1=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C30H40N6O6.C2H4O2/c1-18(2)14-24-29(41)32-13-12-23(35-27(39)22(31)15-20-8-10-21(37)11-9-20)28(40)33-17-26(38)34-25(30(42)36-24)16-19-6-4-3-5-7-19;1-2(3)4/h3-11,18,22-25,37H,12-17,31H2,1-2H3,(H,32,41)(H,33,40)(H,34,38)(H,35,39)(H,36,42);1H3,(H,3,4)/t22-,23+,24-,25+;/m0./s1 JMWZXXPNZPKFJU-KSAVMQLZSA-N 50027503 Acetate1-(6-benzyl-3-isobutyl-2,5,8,11-tetraoxo-1,4,7,10tetraaza-cyclotetradec-12-ylcarbamoyl)-2-(4-hydroxy-phenyl)-ethyl-ammonium;::CHEMBL2372203 Mu-type opioid receptor Cavia cutleri 14 ChEMBL 10.1021/jm00354a008 10.7270/Q2HQ40G9 6296388 DiMaio, J; Nguyen, TM; Lemieux, C; Schiller, PW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027503 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027503&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73354741 103936973 CHEMBL2372203 ZINC36215581 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50028743 CC(O)=O.CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O InChI=1S/C29H40N6O6.C2H4O2/c1-17(2)13-23(26(31)38)35-29(41)24(15-19-7-5-4-6-8-19)34-25(37)16-32-27(39)18(3)33-28(40)22(30)14-20-9-11-21(36)12-10-20;1-2(3)4/h4-12,17-18,22-24,36H,13-16,30H2,1-3H3,(H2,31,38)(H,32,39)(H,33,40)(H,34,37)(H,35,41);1H3,(H,3,4)/t18-,22+,23+,24+;/m1./s1 CQOMFFDBVNJVDP-KBUZRCILSA-N 50027508 Acetate1-(6-benzyl-3-isobutyl-2,5,8,11-tetraoxo-1,4,7,10tetraaza-cyclohexadec-12-ylcarbamoyl)-2-(4-hydroxy-phenyl)-ethyl-ammonium;::CHEMBL2372197 Mu-type opioid receptor Cavia cutleri 7.6 ChEMBL 10.1021/jm00354a008 10.7270/Q2HQ40G9 6296388 DiMaio, J; Nguyen, TM; Lemieux, C; Schiller, PW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027508 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027508&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71308736 103936978 CHEMBL2372197 ZINC36215596 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50028746 CC(O)=O.CC(C)C[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H](CCCCNC1=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C32H44N6O6.C2H4O2/c1-20(2)16-26-31(43)34-15-7-6-10-25(37-29(41)24(33)17-22-11-13-23(39)14-12-22)30(42)35-19-28(40)36-27(32(44)38-26)18-21-8-4-3-5-9-21;1-2(3)4/h3-5,8-9,11-14,20,24-27,39H,6-7,10,15-19,33H2,1-2H3,(H,34,43)(H,35,42)(H,36,40)(H,37,41)(H,38,44);1H3,(H,3,4)/t24-,25+,26-,27-;/m0./s1 FVBMNJRVPFTJGJ-VHLUBNKBSA-N 50027510 Acetate1-(6-benzyl-3-isobutyl-2,5,8,11-tetraoxo-1,4,7,10tetraaza-cyclohexadec-12-ylcarbamoyl)-2-(4-hydroxy-phenyl)-ethyl-ammonium;::CHEMBL2372207 Mu-type opioid receptor Cavia cutleri 4.8 ChEMBL 10.1021/jm00354a008 10.7270/Q2HQ40G9 6296388 DiMaio, J; Nguyen, TM; Lemieux, C; Schiller, PW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027510 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027510&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73351749 103936980 CHEMBL2372207 ZINC36215568 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50028749 CC(O)=O.N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CCCCNC(=O)[C@H](Cc2ccccc2)NC(=O)CNC1=O InChI=1S/C26H33N5O5.C2H4O2/c27-20(14-18-9-11-19(32)12-10-18)24(34)31-21-8-4-5-13-28-26(36)22(15-17-6-2-1-3-7-17)30-23(33)16-29-25(21)35;1-2(3)4/h1-3,6-7,9-12,20-22,32H,4-5,8,13-16,27H2,(H,28,36)(H,29,35)(H,30,33)(H,31,34);1H3,(H,3,4)/t20-,21+,22-;/m0./s1 NGEIZKGBTUEZOD-JDCPXUKWSA-N 50027506 Acetate1-(3-benzyl-2,5,8-trioxo-1,4,7triaza-cyclotridec-9-ylcarbamoyl)-2-(4-hydroxy-phenyl)-ethyl-ammonium;::CHEMBL2372200 Mu-type opioid receptor Cavia cutleri 7.1 ChEMBL 10.1021/jm00354a008 10.7270/Q2HQ40G9 6296388 DiMaio, J; Nguyen, TM; Lemieux, C; Schiller, PW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027506 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027506&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73353231 103936976 CHEMBL2372200 ZINC36215627 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50028750 CC(O)=O.CCC[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(N)=O InChI=1S/C31H44N6O6.C2H4O2/c1-4-8-24(36-29(41)23(32)16-21-11-13-22(38)14-12-21)30(42)34-18-27(39)35-26(17-20-9-6-5-7-10-20)31(43)37-25(28(33)40)15-19(2)3;1-2(3)4/h5-7,9-14,19,23-26,38H,4,8,15-18,32H2,1-3H3,(H2,33,40)(H,34,42)(H,35,39)(H,36,41)(H,37,43);1H3,(H,3,4)/t23-,24+,25-,26-;/m0./s1 JRRHGFZKNYEKNL-DNTHEOLHSA-N 50027511 Acetate1-[1-({[1-(1-carbamoyl-3-methyl-butylcarbamoyl)-2-phenyl-ethylcarbamoyl]-methyl}-carbamoyl)-butylcarbamoyl]-2-(4-hydroxy-phenyl)-ethyl-ammonium;::CHEMBL2372199 Mu-type opioid receptor Cavia cutleri 23 ChEMBL 10.1021/jm00354a008 10.7270/Q2HQ40G9 6296388 DiMaio, J; Nguyen, TM; Lemieux, C; Schiller, PW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027511 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027511&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73345652 103936981 CHEMBL2372199 ZINC36215650 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50028751 CC(O)=O.CC(C)C[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H](CNC1=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C29H38N6O6.C2H4O2/c1-17(2)12-22-27(39)31-15-24(35-26(38)21(30)13-19-8-10-20(36)11-9-19)28(40)32-16-25(37)33-23(29(41)34-22)14-18-6-4-3-5-7-18;1-2(3)4/h3-11,17,21-24,36H,12-16,30H2,1-2H3,(H,31,39)(H,32,40)(H,33,37)(H,34,41)(H,35,38);1H3,(H,3,4)/t21-,22-,23-,24+;/m0./s1 CGBYGRYIQKCHJH-LYHZXGHASA-N 50027509 Acetate1-(6-benzyl-3-isobutyl-2,5,8,11-tetraoxo-1,4,7,10tetraaza-cyclotridec-12-ylcarbamoyl)-2-(4-hydroxy-phenyl)-ethyl-ammonium;::CHEMBL2372202 Mu-type opioid receptor Cavia cutleri 23 ChEMBL 10.1021/jm00354a008 10.7270/Q2HQ40G9 6296388 DiMaio, J; Nguyen, TM; Lemieux, C; Schiller, PW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027509&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73354739 103936979 CHEMBL2372202 ZINC36215639 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50028752 CC(O)=O.CC(C)C[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H](CCCNC1=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C31H42N6O6.C2H4O2/c1-19(2)15-25-30(42)33-14-6-9-24(36-28(40)23(32)16-21-10-12-22(38)13-11-21)29(41)34-18-27(39)35-26(31(43)37-25)17-20-7-4-3-5-8-20;1-2(3)4/h3-5,7-8,10-13,19,23-26,38H,6,9,14-18,32H2,1-2H3,(H,33,42)(H,34,41)(H,35,39)(H,36,40)(H,37,43);1H3,(H,3,4)/t23-,24+,25-,26-;/m0./s1 RZBOVQWKMHOZQH-DNTHEOLHSA-N 50027507 Acetate1-(6-benzyl-3-isobutyl-2,5,8,11-tetraoxo-1,4,7,10tetraaza-cyclopentadec-12-ylcarbamoyl)-2-(4-hydroxy-phenyl)-ethyl-ammonium;::CHEMBL2372201 Mu-type opioid receptor Cavia cutleri 48 ChEMBL 10.1021/jm00354a008 10.7270/Q2HQ40G9 6296388 DiMaio, J; Nguyen, TM; Lemieux, C; Schiller, PW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027507 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027507&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73353233 103936977 CHEMBL2372201 ZINC36215608 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50028757 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C28H37N5O7/c1-17(2)12-23(28(39)40)33-27(38)22(14-18-6-4-3-5-7-18)32-25(36)16-30-24(35)15-31-26(37)21(29)13-19-8-10-20(34)11-9-19/h3-11,17,21-23,34H,12-16,29H2,1-2H3,(H,30,35)(H,31,37)(H,32,36)(H,33,38)(H,39,40)/t21-,22-,23-/m0/s1 URLZCHNOLZSCCA-VABKMULXSA-N 50001465 (S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::([Leu]-enkephalin)2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::(enkephalin)2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-1-oxo-3-phenyl-propylamino]-4-methyl-pentanoic acid::2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::2-[1-[1-amino-2-(4-hydroxyphenyl)-(1S)-ethylcarboxamidomethylcarboxamidomethylcarboxamido]-2-phenyl-(1S)-ethylcarboxamido]-4-methyl-(2S)-pentanoic acid::2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid(Enkephalin)::2-{1-[1-amino-2-(4-hydroxyphenyl)ethylcarboxamidomethylcarboxamidomethylcarboxamido]-2-phenylethylcarboxamido}-4-methylpentanoic acid::CHEMBL8234::ENKEPHALIN::Leu-ENKEPHALIN::Leu5-Enkephalin::Tyr-Gly-Gly-Phe-Leu-OH Mu-type opioid receptor Cavia cutleri 246 ChEMBL 10.1021/jm00354a008 10.7270/Q2HQ40G9 6296388 DiMaio, J; Nguyen, TM; Lemieux, C; Schiller, PW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001465&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 461776 103915930 CHEMBL8234 ZINC14952116 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50028770 CN1CC[C@]23CCCC[C@H]2[C@H]1Cc1ccc(O)cc31 InChI=1S/C17H23NO/c1-18-9-8-17-7-3-2-4-14(17)16(18)10-12-5-6-13(19)11-15(12)17/h5-6,11,14,16,19H,2-4,7-10H2,1H3/t14-,16+,17+/m0/s1 JAQUASYNZVUNQP-USXIJHARSA-N 50017233 CHEMBL592::LEVO-DROMORAN::LEVORPHANOL Mu-type opioid receptor Cavia cutleri 17 ChEMBL 10.1021/jm00354a008 10.7270/Q2HQ40G9 6296388 DiMaio, J; Nguyen, TM; Lemieux, C; Schiller, PW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017233 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017233&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5359272 103928501 CHEMBL592 DB00854 C08014 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50028773 CC(O)=O.CCCC[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(N)=O InChI=1S/C32H46N6O6.C2H4O2/c1-4-5-11-25(37-30(42)24(33)17-22-12-14-23(39)15-13-22)31(43)35-19-28(40)36-27(18-21-9-7-6-8-10-21)32(44)38-26(29(34)41)16-20(2)3;1-2(3)4/h6-10,12-15,20,24-27,39H,4-5,11,16-19,33H2,1-3H3,(H2,34,41)(H,35,43)(H,36,40)(H,37,42)(H,38,44);1H3,(H,3,4)/t24-,25+,26-,27-;/m0./s1 LGUZJRJHWIIKHM-VHLUBNKBSA-N 50027512 Acetate1-[1-({[1-(1-carbamoyl-3-methyl-butylcarbamoyl)-2-phenyl-ethylcarbamoyl]-methyl}-carbamoyl)-pentylcarbamoyl]-2-(4-hydroxy-phenyl)-ethyl-ammonium;::CHEMBL2372210 Mu-type opioid receptor Cavia cutleri 25 ChEMBL 10.1021/jm00354a008 10.7270/Q2HQ40G9 6296388 DiMaio, J; Nguyen, TM; Lemieux, C; Schiller, PW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027512 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027512&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73348665 103936982 CHEMBL2372210 ZINC36215655 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50029936 CN1CC[C@@]23[C@@H]4Oc5c2c(C[C@@H]1[C@@]3(O)CC[C@H]4NC(=O)CCC(=O)N[C@@H]1CC[C@]2(O)[C@H]3Cc4ccc(O)c6O[C@H]1[C@]2(CCN3C)c46)ccc5O InChI=1S/C38H46N4O8/c1-41-15-13-35-29-19-3-5-23(43)31(29)49-33(35)21(9-11-37(35,47)25(41)17-19)39-27(45)7-8-28(46)40-22-10-12-38(48)26-18-20-4-6-24(44)32-30(20)36(38,34(22)50-32)14-16-42(26)2/h3-6,21-22,25-26,33-34,43-44,47-48H,7-18H2,1-2H3,(H,39,45)(H,40,46)/t21-,22-,25?,26?,33-,34-,35?,36?,37+,38+/m0/s1 OKLLEUZELZAWAK-MJOAYLQUSA-N 50021501 1N,4N-di[10,17-dihydroxy-4-methyl-(13R,14S,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-yl]succinamide::CHEMBL3350134 Mu-type opioid receptor Cavia cutleri 23 ChEMBL 10.1021/jm00160a010 10.7270/Q21Z43DQ 3020244 Portoghese, PS; Larson, DL; Sayre, LM; Yim, CB; Ronsisvalle, G; Tam, SW; Takemori, AE TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021501 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021501&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 118718759 103932204 CHEMBL3350134CHEMBL52028 ZINC49863796 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50029939 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)NC(=O)CCC(=O)N[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45 InChI=1S/C44H54N4O8/c49-29-7-5-25-19-31-43(53)13-11-27(39-41(43,35(25)37(29)55-39)15-17-47(31)21-23-1-2-23)45-33(51)9-10-34(52)46-28-12-14-44(54)32-20-26-6-8-30(50)38-36(26)42(44,40(28)56-38)16-18-48(32)22-24-3-4-24/h5-8,23-24,27-28,31-32,39-40,49-50,53-54H,1-4,9-22H2,(H,45,51)(H,46,52)/t27-,28-,31?,32?,39+,40+,41?,42?,43-,44-/m1/s1 DRILWGIBBBJTRW-PESTZLIISA-N 50021498 1N,4N-di[4-cyclopropylmethyl-10,17-dihydroxy-(13R,14R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-yl]succinamide::CHEMBL3350129 Mu-type opioid receptor Cavia cutleri 1.7 ChEMBL 10.1021/jm00160a010 10.7270/Q21Z43DQ 3020244 Portoghese, PS; Larson, DL; Sayre, LM; Yim, CB; Ronsisvalle, G; Tam, SW; Takemori, AE TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021498 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021498&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 101880775 103932201 CHEMBL3350129CHEMBL52860 ZINC95616185 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50029940 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)CC[C@@H]4NC(=O)CNC(=O)CNC(=O)CCC(=O)NCC(=O)NCC(=O)N[C@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c6O[C@@H]1[C@]2(CCN3C)c46)ccc5O InChI=1S/C50H64N10O14/c1-59-15-13-47-41-25-3-5-29(61)43(41)73-45(47)27(9-11-49(47,71)31(59)17-25)57-39(69)23-55-37(67)21-53-35(65)19-51-33(63)7-8-34(64)52-20-36(66)54-22-38(68)56-24-40(70)58-28-10-12-50(72)32-18-26-4-6-30(62)44-42(26)48(50,46(28)74-44)14-16-60(32)2/h3-6,27-28,31-32,45-46,61-62,71-72H,7-24H2,1-2H3,(H,51,63)(H,52,64)(H,53,65)(H,54,66)(H,55,67)(H,56,68)(H,57,69)(H,58,70)/t27-,28-,31?,32?,45-,46-,47?,48?,49+,50+/m0/s1 MJOCGEXOFUSVFI-JQLOKMQHSA-N 50021502 1N,4N-di[10,17-dihydroxy-4-methyl-(13R,14S,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-ylcarbamoylmethylcarbamoylmethylcarbamoylmethyl]succinamide::CHEMBL3350132 Mu-type opioid receptor Cavia cutleri 14 ChEMBL 10.1021/jm00160a010 10.7270/Q21Z43DQ 3020244 Portoghese, PS; Larson, DL; Sayre, LM; Yim, CB; Ronsisvalle, G; Tam, SW; Takemori, AE TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021502 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021502&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 118718757 103932205 CHEMBL3350132CHEMBL267413 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50029944 CN1CC[C@@]23[C@@H]4Oc5c2c(C[C@@H]1[C@@]3(O)CC[C@H]4NC(=O)CNC(=O)CCC(=O)NCC(=O)N[C@@H]1CC[C@]2(O)[C@H]3Cc4ccc(O)c6O[C@H]1[C@]2(CCN3C)c46)ccc5O InChI=1S/C42H52N6O10/c1-47-15-13-39-33-21-3-5-25(49)35(33)57-37(39)23(9-11-41(39,55)27(47)17-21)45-31(53)19-43-29(51)7-8-30(52)44-20-32(54)46-24-10-12-42(56)28-18-22-4-6-26(50)36-34(22)40(42,38(24)58-36)14-16-48(28)2/h3-6,23-24,27-28,37-38,49-50,55-56H,7-20H2,1-2H3,(H,43,51)(H,44,52)(H,45,53)(H,46,54)/t23-,24-,27?,28?,37-,38-,39?,40?,41+,42+/m0/s1 RCPCDUXOVQUCRE-QVHGJMOWSA-N 50021492 1N,4N-di[10,17-dihydroxy-4-methyl-(13R,14S,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-ylcarbamoylmethyl]succinamide::CHEMBL3350135 Mu-type opioid receptor Cavia cutleri 18 ChEMBL 10.1021/jm00160a010 10.7270/Q21Z43DQ 3020244 Portoghese, PS; Larson, DL; Sayre, LM; Yim, CB; Ronsisvalle, G; Tam, SW; Takemori, AE TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021492 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021492&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 118718760 103932195 CHEMBL3350135CHEMBL299138 ZINC95542814 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50029945 CN1CC[C@@]23[C@@H]4Oc5c2c(C[C@@H]1[C@@]3(O)CC[C@H]4NC(=O)CNC(=O)CNC(=O)CNC(=O)CCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H]1CC[C@]2(O)[C@H]3Cc4ccc(O)c6O[C@H]1[C@]2(CCN3C)c46)ccc5O InChI=1S/C46H58N8O12/c1-53-15-13-43-37-23-3-5-27(55)39(37)65-41(43)25(9-11-45(43,63)29(53)17-23)51-35(61)21-49-33(59)19-47-31(57)7-8-32(58)48-20-34(60)50-22-36(62)52-26-10-12-46(64)30-18-24-4-6-28(56)40-38(24)44(46,42(26)66-40)14-16-54(30)2/h3-6,25-26,29-30,41-42,55-56,63-64H,7-22H2,1-2H3,(H,47,57)(H,48,58)(H,49,59)(H,50,60)(H,51,61)(H,52,62)/t25-,26-,29?,30?,41-,42-,43?,44?,45+,46+/m0/s1 OTMKLHUGNDKIGO-UBQJXKISSA-N 50021497 1N,4N-di[10,17-dihydroxy-4-methyl-(13R,14S,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-ylcarbamoylmethylcarbamoylmethyl]succinamide::CHEMBL3350140 Mu-type opioid receptor Cavia cutleri 22 ChEMBL 10.1021/jm00160a010 10.7270/Q21Z43DQ 3020244 Portoghese, PS; Larson, DL; Sayre, LM; Yim, CB; Ronsisvalle, G; Tam, SW; Takemori, AE TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021497 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021497&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 118718765 103932200 CHEMBL3350140CHEMBL301524 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50029946 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)CC[C@@H]4NC(=O)CCC(=O)N[C@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c6O[C@@H]1[C@]2(CCN3C)c46)ccc5O InChI=1S/C38H46N4O8/c1-41-15-13-35-29-19-3-5-23(43)31(29)49-33(35)21(9-11-37(35,47)25(41)17-19)39-27(45)7-8-28(46)40-22-10-12-38(48)26-18-20-4-6-24(44)32-30(20)36(38,34(22)50-32)14-16-42(26)2/h3-6,21-22,25-26,33-34,43-44,47-48H,7-18H2,1-2H3,(H,39,45)(H,40,46)/t21-,22-,25?,26?,33-,34-,35?,36?,37+,38+/m1/s1 OKLLEUZELZAWAK-WWOLPUCPSA-N 50021504 1N,4N-di[10,17-dihydroxy-4-methyl-(13S,14R,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-yl]succinamide::CHEMBL3350127 Mu-type opioid receptor Cavia cutleri 50 ChEMBL 10.1021/jm00160a010 10.7270/Q21Z43DQ 3020244 Portoghese, PS; Larson, DL; Sayre, LM; Yim, CB; Ronsisvalle, G; Tam, SW; Takemori, AE TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021504 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021504&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 118718754 103932207 CHEMBL3350127CHEMBL52996 ZINC49863814 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50029952 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)CC[C@@H]4NC(=O)CNC(=O)CNC(=O)CNC(=O)CCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c6O[C@@H]1[C@]2(CCN3C)c46)ccc5O InChI=1S/C50H64N10O14/c1-59-15-13-47-41-25-3-5-29(61)43(41)73-45(47)27(9-11-49(47,71)31(59)17-25)57-39(69)23-55-37(67)21-53-35(65)19-51-33(63)7-8-34(64)52-20-36(66)54-22-38(68)56-24-40(70)58-28-10-12-50(72)32-18-26-4-6-30(62)44-42(26)48(50,46(28)74-44)14-16-60(32)2/h3-6,27-28,31-32,45-46,61-62,71-72H,7-24H2,1-2H3,(H,51,63)(H,52,64)(H,53,65)(H,54,66)(H,55,67)(H,56,68)(H,57,69)(H,58,70)/t27-,28-,31?,32?,45-,46-,47?,48?,49+,50+/m1/s1 MJOCGEXOFUSVFI-PIDSNTOSSA-N 50021496 1N,4N-di[10,17-dihydroxy-4-methyl-(13S,14R,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-ylcarbamoylmethylcarbamoylmethylcarbamoylmethyl]succinamide::CHEMBL3350128 Mu-type opioid receptor Cavia cutleri 34 ChEMBL 10.1021/jm00160a010 10.7270/Q21Z43DQ 3020244 Portoghese, PS; Larson, DL; Sayre, LM; Yim, CB; Ronsisvalle, G; Tam, SW; Takemori, AE TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021496 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021496&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 118718755 103932199 CHEMBL3350128CHEMBL412482 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50029956 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)NC(=O)CNC(=O)CNC(=O)CCC(=O)NCC(=O)NCC(=O)N[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45 InChI=1S/C52H66N8O12/c61-33-7-5-29-19-35-51(69)13-11-31(47-49(51,43(29)45(33)71-47)15-17-59(35)25-27-1-2-27)57-41(67)23-55-39(65)21-53-37(63)9-10-38(64)54-22-40(66)56-24-42(68)58-32-12-14-52(70)36-20-30-6-8-34(62)46-44(30)50(52,48(32)72-46)16-18-60(36)26-28-3-4-28/h5-8,27-28,31-32,35-36,47-48,61-62,69-70H,1-4,9-26H2,(H,53,63)(H,54,64)(H,55,65)(H,56,66)(H,57,67)(H,58,68)/t31-,32-,35?,36?,47+,48+,49?,50?,51-,52-/m1/s1 XQVPPJLZOSQCEL-SWJMQMGJSA-N 50021495 1N,4N-di[4-cyclopropylmethyl-10,17-dihydroxy-(13R,14R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-ylcarbamoylmethylcarbamoylmethyl]succinamide::CHEMBL3350130 Mu-type opioid receptor Cavia cutleri 1.5 ChEMBL 10.1021/jm00160a010 10.7270/Q21Z43DQ 3020244 Portoghese, PS; Larson, DL; Sayre, LM; Yim, CB; Ronsisvalle, G; Tam, SW; Takemori, AE TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021495&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15819291 103932198 CHEMBL3350130CHEMBL217644 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50029963 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)CC[C@@H]4NC(=O)CNC(=O)CCC(=O)NCC(=O)N[C@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c6O[C@@H]1[C@]2(CCN3C)c46)ccc5O InChI=1S/C42H52N6O10/c1-47-15-13-39-33-21-3-5-25(49)35(33)57-37(39)23(9-11-41(39,55)27(47)17-21)45-31(53)19-43-29(51)7-8-30(52)44-20-32(54)46-24-10-12-42(56)28-18-22-4-6-26(50)36-34(22)40(42,38(24)58-36)14-16-48(28)2/h3-6,23-24,27-28,37-38,49-50,55-56H,7-20H2,1-2H3,(H,43,51)(H,44,52)(H,45,53)(H,46,54)/t23-,24-,27?,28?,37-,38-,39?,40?,41+,42+/m1/s1 RCPCDUXOVQUCRE-UCLLFJJESA-N 50021491 1N,4N-di[10,17-dihydroxy-4-methyl-(13S,14R,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-ylcarbamoylmethyl]succinamide::CHEMBL3350133 Mu-type opioid receptor Cavia cutleri 44 ChEMBL 10.1021/jm00160a010 10.7270/Q21Z43DQ 3020244 Portoghese, PS; Larson, DL; Sayre, LM; Yim, CB; Ronsisvalle, G; Tam, SW; Takemori, AE TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021491 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021491&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 118718758 103932194 CHEMBL3350133CHEMBL301248 ZINC95609942 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50029964 CN1CC[C@@]23[C@@H]4Oc5c2c(C[C@@H]1[C@@]3(O)CC[C@H]4NC(=O)CNC(=O)CNC(=O)CCC(=O)NCC(=O)NCC(=O)N[C@@H]1CC[C@]2(O)[C@H]3Cc4ccc(O)c6O[C@H]1[C@]2(CCN3C)c46)ccc5O InChI=1S/C46H58N8O12/c1-53-15-13-43-37-23-3-5-27(55)39(37)65-41(43)25(9-11-45(43,63)29(53)17-23)51-35(61)21-49-33(59)19-47-31(57)7-8-32(58)48-20-34(60)50-22-36(62)52-26-10-12-46(64)30-18-24-4-6-28(56)40-38(24)44(46,42(26)66-40)14-16-54(30)2/h3-6,25-26,29-30,41-42,55-56,63-64H,7-22H2,1-2H3,(H,47,57)(H,48,58)(H,49,59)(H,50,60)(H,51,61)(H,52,62)/t25-,26-,29?,30?,41-,42-,43?,44?,45+,46+/m1/s1 OTMKLHUGNDKIGO-PINPYOFOSA-N 50021490 1N,4N-di[10,17-dihydroxy-4-methyl-(13S,14R,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-ylcarbamoylmethylcarbamoylmethyl]succinamide::CHEMBL3350136 Mu-type opioid receptor Cavia cutleri 10 ChEMBL 10.1021/jm00160a010 10.7270/Q21Z43DQ 3020244 Portoghese, PS; Larson, DL; Sayre, LM; Yim, CB; Ronsisvalle, G; Tam, SW; Takemori, AE TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021490 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021490&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 118718761 103932193 CHEMBL3350136CHEMBL299950 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50029970 CC(=O)N[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45 InChI=1S/C22H28N2O4/c1-12(25)23-15-6-7-22(27)17-10-14-4-5-16(26)19-18(14)21(22,20(15)28-19)8-9-24(17)11-13-2-3-13/h4-5,13,15,17,20,26-27H,2-3,6-11H2,1H3,(H,23,25)/t15-,17-,20+,21+,22-/m1/s1 QNVKCXXNTZQSAE-VSHLJNTCSA-N 50021500 1N-[4-cyclopropylmethyl-10,17-dihydroxy-(13R,14R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-yl]acetamide::CHEMBL610018 Mu-type opioid receptor Cavia cutleri 1.4 ChEMBL 10.1021/jm00160a010 10.7270/Q21Z43DQ 3020244 Portoghese, PS; Larson, DL; Sayre, LM; Yim, CB; Ronsisvalle, G; Tam, SW; Takemori, AE TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021500 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021500&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14845809 103932203 CHEMBL610018 ZINC29401057 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50029973 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)NC(=O)CNC(=O)CNC(=O)CNC(=O)CCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45 InChI=1S/C56H72N10O14/c67-35-7-5-31-19-37-55(77)13-11-33(51-53(55,47(31)49(35)79-51)15-17-65(37)27-29-1-2-29)63-45(75)25-61-43(73)23-59-41(71)21-57-39(69)9-10-40(70)58-22-42(72)60-24-44(74)62-26-46(76)64-34-12-14-56(78)38-20-32-6-8-36(68)50-48(32)54(56,52(34)80-50)16-18-66(38)28-30-3-4-30/h5-8,29-30,33-34,37-38,51-52,67-68,77-78H,1-4,9-28H2,(H,57,69)(H,58,70)(H,59,71)(H,60,72)(H,61,73)(H,62,74)(H,63,75)(H,64,76)/t33-,34-,37?,38?,51+,52+,53?,54?,55-,56-/m1/s1 UDHTWZXFBYIWTM-OOKUKMSCSA-N 50021493 1N,4N-di[4-cyclopropylmethyl-10,17-dihydroxy-(13R,14R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-ylcarbamoylmethylcarbamoylmethylcarbamoylmethyl]succinamide::CHEMBL3350137 Mu-type opioid receptor Cavia cutleri 1.6 ChEMBL 10.1021/jm00160a010 10.7270/Q21Z43DQ 3020244 Portoghese, PS; Larson, DL; Sayre, LM; Yim, CB; Ronsisvalle, G; Tam, SW; Takemori, AE TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021493&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 118718762 103932196 CHEMBL3350137CHEMBL406272 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50029974 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)CC[C@@H]4NC(C)=O)ccc5O InChI=1S/C19H24N2O4/c1-10(22)20-12-5-6-19(24)14-9-11-3-4-13(23)16-15(11)18(19,17(12)25-16)7-8-21(14)2/h3-4,12,14,17,23-24H,5-9H2,1-2H3,(H,20,22)/t12-,14+,17-,18-,19+/m0/s1 WZKKHNQPRSDJFT-YIBUMMLISA-N 50021503 1N-[10,17-dihydroxy-4-methyl-(13R,14S,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-yl]acetamide::CHEMBL607319 Mu-type opioid receptor Cavia cutleri 180 ChEMBL 10.1021/jm00160a010 10.7270/Q21Z43DQ 3020244 Portoghese, PS; Larson, DL; Sayre, LM; Yim, CB; Ronsisvalle, G; Tam, SW; Takemori, AE TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021503 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021503&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46877852 103932206 CHEMBL607319 ZINC36221109 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50029975 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)NC(=O)CNC(=O)CCC(=O)NCC(=O)N[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45 InChI=1S/C48H60N6O10/c55-31-7-5-27-19-33-47(61)13-11-29(43-45(47,39(27)41(31)63-43)15-17-53(33)23-25-1-2-25)51-37(59)21-49-35(57)9-10-36(58)50-22-38(60)52-30-12-14-48(62)34-20-28-6-8-32(56)42-40(28)46(48,44(30)64-42)16-18-54(34)24-26-3-4-26/h5-8,25-26,29-30,33-34,43-44,55-56,61-62H,1-4,9-24H2,(H,49,57)(H,50,58)(H,51,59)(H,52,60)/t29-,30-,33?,34?,43+,44+,45?,46?,47-,48-/m1/s1 QPJFKKPNQYPLLJ-YZXXDKPGSA-N 50021499 1N,4N-di[4-cyclopropylmethyl-10,17-dihydroxy-(13R,14R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-ylcarbamoylmethyl]succinamide::CHEMBL3350138 Mu-type opioid receptor Cavia cutleri 2.3 ChEMBL 10.1021/jm00160a010 10.7270/Q21Z43DQ 3020244 Portoghese, PS; Larson, DL; Sayre, LM; Yim, CB; Ronsisvalle, G; Tam, SW; Takemori, AE TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021499 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021499&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 118718763 103932202 CHEMBL3350138CHEMBL55551 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50029978 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)CC[C@H]4NC(C)=O)ccc5O InChI=1S/C19H24N2O4/c1-10(22)20-12-5-6-19(24)14-9-11-3-4-13(23)16-15(11)18(19,17(12)25-16)7-8-21(14)2/h3-4,12,14,17,23-24H,5-9H2,1-2H3,(H,20,22)/t12-,14?,17+,18?,19-/m1/s1 WZKKHNQPRSDJFT-LHJOXNPXSA-N 50021494 1N-[10,17-dihydroxy-4-methyl-(13R,14R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-yl]acetamide::CHEMBL3350139 Mu-type opioid receptor Cavia cutleri 63 ChEMBL 10.1021/jm00160a010 10.7270/Q21Z43DQ 3020244 Portoghese, PS; Larson, DL; Sayre, LM; Yim, CB; Ronsisvalle, G; Tam, SW; Takemori, AE TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021494 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021494&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 118718764 103932197 CHEMBL3350139CHEMBL55485 ZINC36221115 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50029985 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C63H103N21O13/c1-5-37(4)51(58(94)80-44(20-13-29-74-63(70)71)59(95)84-30-14-21-48(84)57(93)81-45(60(96)97)17-9-10-26-64)83-54(90)43(19-12-28-73-62(68)69)78-53(89)42(18-11-27-72-61(66)67)79-55(91)46(31-36(2)3)82-56(92)47(33-38-15-7-6-8-16-38)77-50(87)35-75-49(86)34-76-52(88)41(65)32-39-22-24-40(85)25-23-39/h6-8,15-16,22-25,36-37,41-48,51,85H,5,9-14,17-21,26-35,64-65H2,1-4H3,(H,75,86)(H,76,88)(H,77,87)(H,78,89)(H,79,91)(H,80,94)(H,81,93)(H,82,92)(H,83,90)(H,96,97)(H4,66,67,72)(H4,68,69,73)(H4,70,71,74)/t37-,41-,42-,43-,44-,45-,46-,47-,48-,51-/m0/s1 WZHQALIQGVYQGG-QFIUEGLPSA-N 50019482 DYNORPHIN A (1-11)::NH2-Tyr-Gly-Gly-D-Trp-Leu-Arg-Arg-D-Trp-Arg-D-Pro-Lys-OH::dynorphin A Mu-type opioid receptor Cavia cutleri 2.9 ChEMBL 10.1021/jm00160a019 10.7270/Q2Z89BCJ 2876099 Gairin, JE; Mazarguil, H; Alvinerie, P; Saint-Pierre, S; Meunier, JC; Cros, J TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019482 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019482&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3086114 103930432 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031084 CC(NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC[S+](C)[O-])NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O InChI=1S/C26H35N5O6S/c1-16(23(28)33)29-26(36)22(15-17-6-4-3-5-7-17)31-25(35)21(12-13-38(2)37)30-24(34)20(27)14-18-8-10-19(32)11-9-18/h3-11,16,20-22,32H,12-15,27H2,1-2H3,(H2,28,33)(H,29,36)(H,30,34)(H,31,35)/t16?,20-,21-,22-,38?/m0/s1 FOWRITAUQAONCE-LNILZMDTSA-N 50019837 2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-N-[1-(carbamoylmethyl-carbamoyl)-2-phenyl-ethyl]-4-methanesulfinyl-butyramide::CHEMBL2372391 Mu-type opioid receptor Cavia cutleri 17 ChEMBL 10.1021/jm00392a002 10.7270/Q20Z73VC 2887656 Marastoni, M; Salvadori, S; Balboni, G; Borea, PA; Marzola, G; Tomatis, R TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019837 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019837&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73345677 103930760 CHEMBL2372391 ZINC29335296 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031085 C[S+]([O-])CC[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(N)=O InChI=1S/C25H33N5O6S/c1-37(36)12-11-20(29-23(33)19(26)13-17-7-9-18(31)10-8-17)25(35)30-21(24(34)28-15-22(27)32)14-16-5-3-2-4-6-16/h2-10,19-21,31H,11-15,26H2,1H3,(H2,27,32)(H,28,34)(H,29,33)(H,30,35)/t19-,20-,21-,37?/m0/s1 FMRTYTBONSAXIF-GGRUBCQMSA-N 50019834 2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-N-[1-(1-carbamoyl-ethylcarbamoyl)-2-phenyl-ethyl]-4-methanesulfinyl-butyramide::CHEMBL2372390 Mu-type opioid receptor Cavia cutleri 6.3 ChEMBL 10.1021/jm00392a002 10.7270/Q20Z73VC 2887656 Marastoni, M; Salvadori, S; Balboni, G; Borea, PA; Marzola, G; Tomatis, R TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019834 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019834&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10052760 103930757 CHEMBL2372390 ZINC36221779 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50028892 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 77 ChEMBL 10.1021/jm00365a017 10.7270/Q2N015J4 6313921 Rice, KC; Konicki, PE; Quirion, R; Burke, TR; Pert, CB TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50028893 CC1C2Cc3ccc(O)cc3C1(C)CCN2CCc1ccccc1 InChI=1S/C22H27NO/c1-16-21-14-18-8-9-19(24)15-20(18)22(16,2)11-13-23(21)12-10-17-6-4-3-5-7-17/h3-9,15-16,21,24H,10-14H2,1-2H3 ZQHYKVKNPWDQSL-UHFFFAOYSA-N 50027791 6,11-Dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(phenazocine)::CHEMBL46399::PHENAZOCINE Mu-type opioid receptor Cavia cutleri 9.8 ChEMBL 10.1021/jm00365a017 10.7270/Q2N015J4 6313921 Rice, KC; Konicki, PE; Quirion, R; Burke, TR; Pert, CB TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027791&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14707 103937240 CHEMBL46399 ZINC01481896 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50028894 Oc1c(Br)cc(Br)cc1C(=O)Nc1cccc(c1)C(F)(F)F InChI=1S/C14H8Br2F3NO2/c15-8-5-10(12(21)11(16)6-8)13(22)20-9-3-1-2-7(4-9)14(17,18)19/h1-6,21H,(H,20,22) VYKKDKFTDMVOBU-UHFFFAOYSA-N 50027790 3,5-Dibromo-2-hydroxy-N-(3-trifluoromethyl-phenyl)-benzamide::3,5-Dibromo-2-hydroxy-N-(3-trifluoromethyl-phenyl)-benzamide(fluorophen)::CHEMBL283552::Fluorosalan Mu-type opioid receptor Cavia cutleri 12 ChEMBL 10.1021/jm00365a017 10.7270/Q2N015J4 6313921 Rice, KC; Konicki, PE; Quirion, R; Burke, TR; Pert, CB TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027790&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 20906 103937239 CHEMBL283552 ZINC00537744 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50028929 NCCCC[C@H](NC(=O)[C@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C73H101N23O13/c74-29-9-8-20-55(70(108)109)93-68(106)59-24-13-33-96(59)69(107)54(23-12-32-84-73(80)81)92-67(105)58(37-45-39-86-51-19-7-5-17-48(45)51)94-64(102)53(22-11-31-83-72(78)79)90-63(101)52(21-10-30-82-71(76)77)91-66(104)57(36-44-38-85-50-18-6-4-16-47(44)50)95-65(103)56(35-42-14-2-1-3-15-42)89-61(99)41-87-60(98)40-88-62(100)49(75)34-43-25-27-46(97)28-26-43/h1-7,14-19,25-28,38-39,49,52-59,85-86,97H,8-13,20-24,29-37,40-41,74-75H2,(H,87,98)(H,88,100)(H,89,99)(H,90,101)(H,91,104)(H,92,105)(H,93,106)(H,94,102)(H,95,103)(H,108,109)(H4,76,77,82)(H4,78,79,83)(H4,80,81,84)/t49-,52-,53-,54-,55-,56-,57+,58+,59+/m0/s1 HOHGNWXRMOTGET-IMJQSTHTSA-N 50452250 CHEMBL2373014 Mu-type opioid receptor Cavia cutleri 69 ChEMBL 10.1021/jm00160a019 10.7270/Q2Z89BCJ 2876099 Gairin, JE; Mazarguil, H; Alvinerie, P; Saint-Pierre, S; Meunier, JC; Cros, J TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452250 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452250&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73353313 225145621 CHEMBL2373014 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50028930 CC(C)C[C@H](NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C79H110N24O13/c1-44(2)35-61(101-72(111)63(38-47-41-92-55-19-7-4-16-51(47)55)95-66(105)43-94-68(107)62(37-46-40-91-54-18-6-3-15-50(46)54)100-67(106)53(81)36-45-26-28-49(104)29-27-45)71(110)97-57(22-11-31-88-77(82)83)69(108)96-58(23-12-32-89-78(84)85)70(109)102-64(39-48-42-93-56-20-8-5-17-52(48)56)73(112)98-59(24-13-33-90-79(86)87)75(114)103-34-14-25-65(103)74(113)99-60(76(115)116)21-9-10-30-80/h3-8,15-20,26-29,40-42,44,53,57-65,91-93,104H,9-14,21-25,30-39,43,80-81H2,1-2H3,(H,94,107)(H,95,105)(H,96,108)(H,97,110)(H,98,112)(H,99,113)(H,100,106)(H,101,111)(H,102,109)(H,115,116)(H4,82,83,88)(H4,84,85,89)(H4,86,87,90)/t53-,57-,58-,59-,60-,61-,62+,63+,64+,65+/m0/s1 MAGOLJWDWUGTHL-HPRGOQFHSA-N 50019487 CHEMBL2373013::NH2-Tyr-D-Trp-Gly-D-Trp-Leu-Arg-Arg-D-Trp-Arg-D-Pro-Lys-OH Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm00160a019 10.7270/Q2Z89BCJ 2876099 Gairin, JE; Mazarguil, H; Alvinerie, P; Saint-Pierre, S; Meunier, JC; Cros, J TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019487 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019487&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73351837 103930437 CHEMBL2373013 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50028931 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C77H109N23O13/c1-44(2)36-59(98-70(108)60(38-45-16-4-3-5-17-45)92-64(102)43-91-66(104)61(39-47-41-89-53-20-8-6-18-50(47)53)97-65(103)52(79)37-46-27-29-49(101)30-28-46)69(107)94-55(23-12-32-86-75(80)81)67(105)93-56(24-13-33-87-76(82)83)68(106)99-62(40-48-42-90-54-21-9-7-19-51(48)54)71(109)95-57(25-14-34-88-77(84)85)73(111)100-35-15-26-63(100)72(110)96-58(74(112)113)22-10-11-31-78/h3-9,16-21,27-30,41-42,44,52,55-63,89-90,101H,10-15,22-26,31-40,43,78-79H2,1-2H3,(H,91,104)(H,92,102)(H,93,105)(H,94,107)(H,95,109)(H,96,110)(H,97,103)(H,98,108)(H,99,106)(H,112,113)(H4,80,81,86)(H4,82,83,87)(H4,84,85,88)/t52-,55-,56-,57-,58-,59-,60-,61+,62+,63+/m0/s1 ZGEZENMQCHYYOS-JRAGJKLTSA-N 50452249 CHEMBL2373012 Mu-type opioid receptor Cavia cutleri 8890 ChEMBL 10.1021/jm00160a019 10.7270/Q2Z89BCJ 2876099 Gairin, JE; Mazarguil, H; Alvinerie, P; Saint-Pierre, S; Meunier, JC; Cros, J TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452249 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452249&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73347231 225145620 CHEMBL2373012 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50028938 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C68H102N22O13/c1-39(2)32-51(88-61(98)52(34-40-14-4-3-5-15-40)83-56(93)38-81-55(92)37-82-57(94)45(70)33-41-23-25-43(91)26-24-41)60(97)85-47(19-10-28-77-66(71)72)58(95)84-48(20-11-29-78-67(73)74)59(96)89-53(35-42-36-80-46-17-7-6-16-44(42)46)62(99)86-49(21-12-30-79-68(75)76)64(101)90-31-13-22-54(90)63(100)87-50(65(102)103)18-8-9-27-69/h3-7,14-17,23-26,36,39,45,47-54,80,91H,8-13,18-22,27-35,37-38,69-70H2,1-2H3,(H,81,92)(H,82,94)(H,83,93)(H,84,95)(H,85,97)(H,86,99)(H,87,100)(H,88,98)(H,89,96)(H,102,103)(H4,71,72,77)(H4,73,74,78)(H4,75,76,79)/t45-,47-,48-,49-,50-,51-,52-,53+,54+/m0/s1 RLPFKKCEQVABBW-WGCJGFSLSA-N 50019480 CHEMBL2373009::NH2-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-D-Trp-Arg-D-Pro-Lys-OH Mu-type opioid receptor Cavia cutleri 2.8 ChEMBL 10.1021/jm00160a019 10.7270/Q2Z89BCJ 2876099 Gairin, JE; Mazarguil, H; Alvinerie, P; Saint-Pierre, S; Meunier, JC; Cros, J TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019480&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73345747 103930430 CHEMBL2373009 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50035754 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)N)C(C)C)C(=O)NCC(N)=O InChI=1S/C28H43N7O8/c1-14(2)22(27(42)31-13-20(30)36)35-28(43)23(15(3)4)34-26(41)19(12-21(37)38)33-25(40)18(32-24(39)16(5)29)11-17-9-7-6-8-10-17/h6-10,14-16,18-19,22-23H,11-13,29H2,1-5H3,(H2,30,36)(H,31,42)(H,32,39)(H,33,40)(H,34,41)(H,35,43)(H,37,38)/t16-,18+,19+,22+,23+/m1/s1 HGPPSHNJMSQHSO-XJURRUFCSA-N 50038424 (S)-3-[(S)-2-((R)-2-Amino-propionylamino)-3-phenyl-propionylamino]-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL49581 Mu-type opioid receptor Cavia cutleri 2900 ChEMBL 10.1021/jm00038a004 10.7270/Q2N58N1K 8021915 Qian, X; Kover, KE; Shenderovich, MD; Lou, BS; Misicka, A; Zalewska, T; Horvath, R; Davis, P; Bilsky, EJ; Porreca, F University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038424 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038424&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44294260 103945797 CHEMBL49581 ZINC29462459 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50034548 Oc1ccc2CC3[C@@H]4Cc5c([nH]c6ccccc56)[C@@H]5Oc1c2[C@]45CCN3CCc1ccccc1 InChI=1S/C30H28N2O2/c33-25-11-10-19-16-24-22-17-21-20-8-4-5-9-23(20)31-27(21)29-30(22,26(19)28(25)34-29)13-15-32(24)14-12-18-6-2-1-3-7-18/h1-11,22,24,29,31,33H,12-17H2/t22-,24?,29-,30-/m0/s1 ZEFONCRJOSMQGI-ADSSBNEFSA-N 50001677 22-phenethyl-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaen-16-ol Mu-type opioid receptor Cavia cutleri 173 ChEMBL 10.1021/jm00101a009 10.7270/Q2DF6RTZ 1333013 Portoghese, PS; Larson, DL; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001677 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001677&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44357117 103916107 ZINC13729844 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50034549 Oc1ccc2CC3NCC[C@@]45[C@@H](Oc1c24)c1[nH]c2ccccc2c1C[C@@H]35 InChI=1S/C22H20N2O2/c25-17-6-5-11-9-16-14-10-13-12-3-1-2-4-15(12)24-19(13)21-22(14,7-8-23-16)18(11)20(17)26-21/h1-6,14,16,21,23-25H,7-10H2/t14-,16?,21-,22-/m0/s1 JXRNSGYOXHMHBN-SCDTUJDPSA-N 50001674 14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaen-16-ol::CHEMBL344000 Mu-type opioid receptor Cavia cutleri 375 ChEMBL 10.1021/jm00101a009 10.7270/Q2DF6RTZ 1333013 Portoghese, PS; Larson, DL; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001674 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001674&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44357097 103916104 CHEMBL344000 ZINC13729842 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50034554 Oc1ccc2CC3NCC[C@@]45[C@@H](Oc1c24)c1[nH]c2ccccc2c1C[C@@]35O InChI=1S/C22H20N2O3/c25-15-6-5-11-9-16-22(26)10-13-12-3-1-2-4-14(12)24-18(13)20-21(22,7-8-23-16)17(11)19(15)27-20/h1-6,16,20,23-26H,7-10H2/t16?,20-,21-,22+/m0/s1 QWKWAYNQLADTEK-ZLDJGOMFSA-N 50001675 14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol::CHEMBL285563 Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm00101a009 10.7270/Q2DF6RTZ 1333013 Portoghese, PS; Larson, DL; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001675 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001675&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44282798 103916105 CHEMBL285563 ZINC13729838 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50035755 CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23-,24-/m0/s1 MCMMCRYPQBNCPH-DVKRWUGUSA-N 50001683 13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid::7-Benzyl-10-{[3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL294616::DPDPE Mu-type opioid receptor Cavia cutleri 7300 ChEMBL 10.1021/jm00038a004 10.7270/Q2N58N1K 8021915 Qian, X; Kover, KE; Shenderovich, MD; Lou, BS; Misicka, A; Zalewska, T; Horvath, R; Davis, P; Bilsky, EJ; Porreca, F University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001683&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299404 103916113 CHEMBL294616 ZINC27520031 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50035761 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)[C@@H](C)c1c(C)cc(O)cc1C)C(C)C)C(=O)NCC(N)=O InChI=1S/C40H58N8O10/c1-19(2)33(39(57)43-18-29(41)50)48-40(58)34(20(3)4)47-37(55)28(17-30(51)52)46-36(54)27(16-25-12-10-9-11-13-25)45-35(53)24(8)44-38(56)32(42)23(7)31-21(5)14-26(49)15-22(31)6/h9-15,19-20,23-24,27-28,32-34,49H,16-18,42H2,1-8H3,(H2,41,50)(H,43,57)(H,44,56)(H,45,53)(H,46,54)(H,47,55)(H,48,58)(H,51,52)/t23-,24+,27-,28-,32-,33-,34-/m0/s1 BRUXMHJPZAHHIV-WRWFCRRXSA-N 50038425 (S)-3-((S)-2-{(R)-2-[(2S,3S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-butyrylamino]-propionylamino}-3-phenyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL49507 Mu-type opioid receptor Cavia cutleri 3840 ChEMBL 10.1021/jm00038a004 10.7270/Q2N58N1K 8021915 Qian, X; Kover, KE; Shenderovich, MD; Lou, BS; Misicka, A; Zalewska, T; Horvath, R; Davis, P; Bilsky, EJ; Porreca, F University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038425 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038425&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10417943 103945798 CHEMBL49507 ZINC95615412 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50035764 C[C@H]([C@H](N)C(=O)N[C@H]1C(=O)NCC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](C(O)=O)C(C)(C)SSC1(C)C)c1c(C)cc(O)cc1C InChI=1S/C33H45N5O7S2/c1-17-13-21(39)14-18(2)24(17)19(3)25(34)29(42)37-26-30(43)35-16-23(40)36-22(15-20-11-9-8-10-12-20)28(41)38-27(31(44)45)33(6,7)47-46-32(26,4)5/h8-14,19,22,25-27,39H,15-16,34H2,1-7H3,(H,35,43)(H,36,40)(H,37,42)(H,38,41)(H,44,45)/t19-,22-,25-,26-,27-/m0/s1 YQDQZNIFGIPRHF-FVGRXGBHSA-N 50038422 (4S,7S,13S)-13-[(2S,3S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-butyrylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid::CHEMBL50284 Mu-type opioid receptor Cavia cutleri 293 ChEMBL 10.1021/jm00038a004 10.7270/Q2N58N1K 8021915 Qian, X; Kover, KE; Shenderovich, MD; Lou, BS; Misicka, A; Zalewska, T; Horvath, R; Davis, P; Bilsky, EJ; Porreca, F University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038422&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10327277 103945795 CHEMBL50284 ZINC27526239 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50034638 Oc1ccc2C[C@H]3N(CC4CC4)CCC45C(Oc1c24)c1[nH]c2ccccc2c1CC35O InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1 WIYUZYBFCWCCQJ-XEWUMVRVSA-N 21864 (21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.0^{1,13}.0^{2,21}.0^{4,12}.0^{5,10}.0^{19,25}]pentacosa-4(12),5,7,9,15,17,19(25)-heptaene-2,16-diol::(8R)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol::NALTRINDOLE::[3H]-naltrindole Mu-type opioid receptor Cavia cutleri 3.8 ChEMBL 10.1021/jm00101a009 10.7270/Q2DF6RTZ 1333013 Portoghese, PS; Larson, DL; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21864&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3034754 49700969 ZINC62153992 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50034639 Oc1ccc2CC3[C@@H]4Cc5c([nH]c6ccccc56)[C@@H]5Oc1c2[C@]45CCN3C\C=C\c1ccccc1 InChI=1S/C31H28N2O2/c34-26-13-12-20-17-25-23-18-22-21-10-4-5-11-24(21)32-28(22)30-31(23,27(20)29(26)35-30)14-16-33(25)15-6-9-19-7-2-1-3-8-19/h1-13,23,25,30,32,34H,14-18H2/b9-6+/t23-,25?,30-,31-/m0/s1 IDQUAQRNJGIRIN-WUQCVZIASA-N 50001678 22-[3-phenyl-(E)-2-propenyl]-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaen-16-ol Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm00101a009 10.7270/Q2DF6RTZ 1333013 Portoghese, PS; Larson, DL; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001678 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001678&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44357545 103916108 ZINC13729847 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50034642 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)C(C)(C)NC(=O)C(C)(C)NC(=O)[C@H](Cc1ccc(O)cc1)N(CC=C)CC=C)C(O)=O InChI=1S/C38H53N5O7/c1-9-20-43(21-10-2)31(24-27-16-18-28(44)19-17-27)33(46)41-38(7,8)36(50)42-37(5,6)35(49)40-29(23-26-14-12-11-13-15-26)32(45)39-30(34(47)48)22-25(3)4/h9-19,25,29-31,44H,1-2,20-24H2,3-8H3,(H,39,45)(H,40,49)(H,41,46)(H,42,50)(H,47,48)/t29-,30-,31-/m0/s1 XUWLAGNFLUARAN-CHQNGUEUSA-N 50006946 2-[2-(2-{2-[2-Diallylamino-3-(4-hydroxy-phenyl)-propionylamino]-2-methyl-propionylamino}-2-methyl-propionylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::CHEMBL47545::ICI-174864 Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm00101a009 10.7270/Q2DF6RTZ 1333013 Portoghese, PS; Larson, DL; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50006946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50006946&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44149909 103920235 CHEMBL47545 ZINC29402878 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50034644 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)Cc1c4[nH]c2ccccc12)ccc5O InChI=1S/C23H22N2O3/c1-25-9-8-22-18-12-6-7-16(26)20(18)28-21(22)19-14(11-23(22,27)17(25)10-12)13-4-2-3-5-15(13)24-19/h2-7,17,21,24,26-27H,8-11H2,1H3/t17-,21+,22+,23-/m1/s1 YQNZUKAKYJMEFE-LMDOGRNLSA-N 50221416 22-methyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol(HCl0.5H2O) (Oxymorphindole, OMI)::22-methyl-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol::CHEMBL401093::OXYMORPHINDOLE Mu-type opioid receptor Cavia cutleri 468 ChEMBL 10.1021/jm00101a009 10.7270/Q2DF6RTZ 1333013 Portoghese, PS; Larson, DL; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221416 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221416&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5491897 104094073 CHEMBL401093 ZINC05966777 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50035869 Oc1ccc2C[C@H]3N(CC4CC4)CCC45C(Oc1c24)c1[nH]c2ccccc2c1CC35O InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1 WIYUZYBFCWCCQJ-XEWUMVRVSA-N 21864 (21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.0^{1,13}.0^{2,21}.0^{4,12}.0^{5,10}.0^{19,25}]pentacosa-4(12),5,7,9,15,17,19(25)-heptaene-2,16-diol::(8R)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol::NALTRINDOLE::[3H]-naltrindole Mu-type opioid receptor Cavia cutleri 3.8 ChEMBL 10.1021/jm00038a019 10.7270/Q20G3KRG 8021929 Portoghese, PS; Ohkawa, S; Moe, ST; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21864&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3034754 49700969 ZINC62153992 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50035870 Oc1ccc2C[C@@H]3[C@@H]4c5[nH]c6ccccc6c5C[C@@H]5Oc1c2[C@]45CCN3CC1CC1 InChI=1S/C26H26N2O2/c29-20-8-7-15-11-19-23-24-17(16-3-1-2-4-18(16)27-24)12-21-26(23,22(15)25(20)30-21)9-10-28(19)13-14-5-6-14/h1-4,7-8,14,19,21,23,27,29H,5-6,9-13H2/t19-,21+,23-,26-/m1/s1 HQLZRENSDIGHBJ-YDOBTQPPSA-N 50038641 22-cyclopropylmethyl-(2R,13S)-14-oxa-4,22-diazaheptacyclo[13.9.1.01,13.02,21.03,11.05,10.019,25]pentacosa-3(11),5(10),6,8,15,17,19(25)-heptaen-16-ol::CHEMBL418105 Mu-type opioid receptor Cavia cutleri 4.9 ChEMBL 10.1021/jm00038a019 10.7270/Q20G3KRG 8021929 Portoghese, PS; Ohkawa, S; Moe, ST; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038641 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038641&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10363496 103945926 CHEMBL418105 ZINC13737353 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50035871 CN1CC[C@]23[C@@H]4Cc5c([nH]c6ccccc56)[C@H]2[C@H]1Cc1ccc(O)c(O4)c31 InChI=1S/C23H22N2O2/c1-25-9-8-23-18-11-14-13-4-2-3-5-15(13)24-21(14)20(23)16(25)10-12-6-7-17(26)22(27-18)19(12)23/h2-7,16,18,20,24,26H,8-11H2,1H3/t16-,18+,20-,23-/m1/s1 TVTQHEAJUSXWSV-RWSUSOHTSA-N 50038642 22-methyl-(2R,13S)-14-oxa-4,22-diazaheptacyclo[13.9.1.01,13.02,21.03,11.05,10.019,25]pentacosa-3(11),5(10),6,8,15,17,19(25)-heptaen-16-ol::CHEMBL291973 Mu-type opioid receptor Cavia cutleri 920 ChEMBL 10.1021/jm00038a019 10.7270/Q20G3KRG 8021929 Portoghese, PS; Ohkawa, S; Moe, ST; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038642 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038642&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10338455 103945927 CHEMBL291973 ZINC29546399 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50035873 Oc1ccc2C[C@H]3N(CC4CC4)CCC45C(Oc1c24)c1[nH]c2ccccc2c1CC35O InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1 WIYUZYBFCWCCQJ-XEWUMVRVSA-N 21864 (21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.0^{1,13}.0^{2,21}.0^{4,12}.0^{5,10}.0^{19,25}]pentacosa-4(12),5,7,9,15,17,19(25)-heptaene-2,16-diol::(8R)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol::NALTRINDOLE::[3H]-naltrindole Mu-type opioid receptor Cavia cutleri 11200 ChEMBL 10.1021/jm00038a019 10.7270/Q20G3KRG 8021929 Portoghese, PS; Ohkawa, S; Moe, ST; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21864&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3034754 49700969 ZINC62153992 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033635 Oc1ccc2CC3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C1=C(C[C@@]35O)C(C2=C(O1)[C@@H]1Oc3c4c(CC5N(CC6CC6)CC[C@@]14[C@@]5(O)C2)ccc3O)c1ccccc1 InChI=1S/C47H48N2O7/c50-31-12-10-27-18-33-46(52)20-29-35(26-4-2-1-3-5-26)30-21-47(53)34-19-28-11-13-32(51)41-37(28)45(47,15-17-49(34)23-25-8-9-25)43(56-41)39(30)54-38(29)42-44(46,36(27)40(31)55-42)14-16-48(33)22-24-6-7-24/h1-5,10-13,24-25,33-35,42-43,50-53H,6-9,14-23H2/t33?,34?,35?,42-,43-,44-,45-,46+,47+/m0/s1 AKPAHSIBCCFBBS-SJAHWYOTSA-N 50009130 bis(4-cyclopropylmethyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,14-tetraene-10,17-diol)4-phenyl-4H-pyran Mu-type opioid receptor Cavia cutleri 29 ChEMBL 10.1021/jm00108a008 10.7270/Q2C53MF5 1849995 Portoghese, PS; Garzon-Aburbeh, A; Nagase, H; Lin, CE; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009130&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14845230 103922187 ZINC96178788 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033640 Oc1ccc2CC3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1sc2[C@@H]4Oc6c7c(CC8N(CC9CC9)CC[C@@]47[C@@]8(O)Cc2c1C[C@@]35O)ccc6O InChI=1S/C40H42N2O6S/c43-25-7-5-21-13-27-39(45)15-23-24-16-40(46)28-14-22-6-8-26(44)32-30(22)38(40,10-12-42(28)18-20-3-4-20)36(48-32)34(24)49-33(23)35-37(39,29(21)31(25)47-35)9-11-41(27)17-19-1-2-19/h5-8,19-20,27-28,35-36,43-46H,1-4,9-18H2/t27?,28?,35-,36-,37-,38-,39+,40+/m0/s1 NQNVFVDZFZCYFC-VLLWXXIVSA-N 50009127 bis(4-cyclopropylmethyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,14-tetraene-10,17-diol)thiphene Mu-type opioid receptor Cavia cutleri 189 ChEMBL 10.1021/jm00108a008 10.7270/Q2C53MF5 1849995 Portoghese, PS; Garzon-Aburbeh, A; Nagase, H; Lin, CE; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009127 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009127&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14845225 103922184 ZINC58538189 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033641 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2[C@@H]4Oc6c7c(C[C@H]8N(CC9CC9)CC[C@@]47[C@@]8(O)Cc2c1C[C@@]35O)ccc6O InChI=1S/C40H43N3O6/c44-25-7-5-21-13-27-39(46)15-23-24-16-40(47)28-14-22-6-8-26(45)34-30(22)38(40,10-12-43(28)18-20-3-4-20)36(49-34)32(24)41-31(23)35-37(39,29(21)33(25)48-35)9-11-42(27)17-19-1-2-19/h5-8,19-20,27-28,35-36,41,44-47H,1-4,9-18H2/t27-,28-,35+,36+,37+,38+,39-,40-/m1/s1 APSUXPSYBJVPPS-YAUKWVCOSA-N 82551 C18130::CAS_105618-26-6::NOR-BNI (HCI)2::NORBNI Mu-type opioid receptor Cavia cutleri 47 ChEMBL 10.1021/jm00108a008 10.7270/Q2C53MF5 1849995 Portoghese, PS; Garzon-Aburbeh, A; Nagase, H; Lin, CE; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82551&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5480230 136350521 C18130 ZINC03995590 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50036088 CCN(CC)C(=O)c1ccc(cc1)[C@@H](N1C[C@H](C)N(CC=C)C[C@H]1C)c1cccc(OC)c1 InChI=1S/C28H39N3O2/c1-7-17-30-19-22(5)31(20-21(30)4)27(25-11-10-12-26(18-25)33-6)23-13-15-24(16-14-23)28(32)29(8-2)9-3/h7,10-16,18,21-22,27H,1,8-9,17,19-20H2,2-6H3/t21-,22+,27+/m0/s1 KQWVAUSXZDRQPZ-OREGWCPLSA-N 50453374 CHEMBL67378 Mu-type opioid receptor Cavia cutleri 1517 ChEMBL 10.1021/jm00040a002 10.7270/Q2ZG6SWK 8035418 Calderon, SN; Rothman, RB; Porreca, F; Flippen-Anderson, JL; McNutt, RW; Xu, H; Smith, LE; Bilsky, EJ; Davis, P; Rice, KC National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453374 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453374&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10321498 225145932 CHEMBL67378 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50036091 CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23-,24-/m0/s1 MCMMCRYPQBNCPH-DVKRWUGUSA-N 50001683 13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid::7-Benzyl-10-{[3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL294616::DPDPE Mu-type opioid receptor Cavia cutleri 7300 ChEMBL 10.1021/jm00040a002 10.7270/Q2ZG6SWK 8035418 Calderon, SN; Rothman, RB; Porreca, F; Flippen-Anderson, JL; McNutt, RW; Xu, H; Smith, LE; Bilsky, EJ; Davis, P; Rice, KC National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001683&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299404 103916113 CHEMBL294616 ZINC27520031 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033736 CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23-,24-/m0/s1 MCMMCRYPQBNCPH-DVKRWUGUSA-N 50001683 13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid::7-Benzyl-10-{[3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL294616::DPDPE Mu-type opioid receptor Cavia cutleri 5500 ChEMBL 10.1021/jm00109a019 10.7270/Q2XW4KCF 1851843 Salvadori, S; Marastoni, M; Balboni, G; Borea, PA; Morari, M; Tomatis, R University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001683&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299404 103916113 CHEMBL294616 ZINC27520031 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033737 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C38H55N9O9/c1-20(2)31(37(55)42-19-30(41)50)47-38(56)32(21(3)4)46-35(53)27(15-16-29(40)49)44-36(54)28(18-23-9-7-6-8-10-23)45-33(51)22(5)43-34(52)26(39)17-24-11-13-25(48)14-12-24/h6-14,20-22,26-28,31-32,48H,15-19,39H2,1-5H3,(H2,40,49)(H2,41,50)(H,42,55)(H,43,52)(H,44,54)(H,45,51)(H,46,53)(H,47,56)/t22-,26-,27-,28-,31-,32-/m0/s1 AYTWCJSQTGWMEQ-LJXGPVSSSA-N 50009183 2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-pentanedioic acid 5-amide 1-({1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-amide)::CHEMBL296782 Mu-type opioid receptor Cavia cutleri 280 ChEMBL 10.1021/jm00109a019 10.7270/Q2XW4KCF 1851843 Salvadori, S; Marastoni, M; Balboni, G; Borea, PA; Morari, M; Tomatis, R University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009183 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009183&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44290460 103922240 CHEMBL296782 ZINC95609759 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033738 CC[C@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)N[C@@H](CC(O)=O)C(N)=O InChI=1S/C36H50N8O10/c1-5-25(35(53)42-26(31(38)49)17-29(47)48)41-36(54)30(19(2)3)44-28(46)18-39-34(52)27(16-21-9-7-6-8-10-21)43-32(50)20(4)40-33(51)24(37)15-22-11-13-23(45)14-12-22/h6-14,19-20,24-27,30,45H,5,15-18,37H2,1-4H3,(H2,38,49)(H,39,52)(H,40,51)(H,41,54)(H,42,53)(H,43,50)(H,44,46)(H,47,48)/t20-,24-,25-,26-,27-,30-/m0/s1 ILERMKZJLBCCNH-UOLJLTGZSA-N 50009184 3-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-methyl-butyrylamino}-butyrylamino)-succinamic acid::CHEMBL2372709 Mu-type opioid receptor Cavia cutleri 130 ChEMBL 10.1021/jm00109a019 10.7270/Q2XW4KCF 1851843 Salvadori, S; Marastoni, M; Balboni, G; Borea, PA; Morari, M; Tomatis, R University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009184 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009184&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73345712 103922241 CHEMBL2372709 ZINC95615407 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033739 CSCC[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(N)=O InChI=1S/C47H64N8O10S2/c1-28(2)23-37(45(63)51-35(20-22-67-4)43(61)52-36(41(49)59)27-40(57)58)53-46(64)39(26-30-13-9-6-10-14-30)55-47(65)38(25-29-11-7-5-8-12-29)54-44(62)34(19-21-66-3)50-42(60)33(48)24-31-15-17-32(56)18-16-31/h5-18,28,33-39,56H,19-27,48H2,1-4H3,(H2,49,59)(H,50,60)(H,51,63)(H,52,61)(H,53,64)(H,54,62)(H,55,65)(H,57,58)/t33-,34-,35-,36-,37-,38-,39-/m0/s1 RLCXCXJUDBWKSH-ZTYVOHGWSA-N 50009196 3-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyrylamino}-3-phenyl-propionylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-4-methylsulfanyl-butyrylamino)-succinamic acid::CHEMBL46540 Mu-type opioid receptor Cavia cutleri 75 ChEMBL 10.1021/jm00109a019 10.7270/Q2XW4KCF 1851843 Salvadori, S; Marastoni, M; Balboni, G; Borea, PA; Morari, M; Tomatis, R University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009196 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009196&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44290198 103922253 CHEMBL46540 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033740 CSCC[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C42H59N7O13S2/c1-23(2)18-30(39(58)45-29(15-17-64-4)38(57)49-33(42(61)62)22-35(53)54)46-41(60)32(21-34(51)52)48-40(59)31(20-24-8-6-5-7-9-24)47-37(56)28(14-16-63-3)44-36(55)27(43)19-25-10-12-26(50)13-11-25/h5-13,23,27-33,50H,14-22,43H2,1-4H3,(H,44,55)(H,45,58)(H,46,60)(H,47,56)(H,48,59)(H,49,57)(H,51,52)(H,53,54)(H,61,62)/t27-,28-,29-,30-,31-,32-,33-/m0/s1 FIIDZOKJHSIFSD-MRNVWEPHSA-N 50009186 2-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyrylamino}-3-phenyl-propionylamino)-3-carboxy-propionylamino]-4-methyl-pentanoylamino}-4-methylsulfanyl-butyrylamino)-succinic acid::CHEMBL297565 Mu-type opioid receptor Cavia cutleri >15000 ChEMBL 10.1021/jm00109a019 10.7270/Q2XW4KCF 1851843 Salvadori, S; Marastoni, M; Balboni, G; Borea, PA; Morari, M; Tomatis, R University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009186 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009186&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44290421 103922243 CHEMBL297565 C02715 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033741 CSCC[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(N)=O InChI=1S/C44H67N9O10S2/c1-26(2)22-35(43(62)50-33(18-21-65-4)41(60)51-34(38(47)57)25-37(55)56)52-40(59)31(12-8-9-19-45)49-44(63)36(24-27-10-6-5-7-11-27)53-42(61)32(17-20-64-3)48-39(58)30(46)23-28-13-15-29(54)16-14-28/h5-7,10-11,13-16,26,30-36,54H,8-9,12,17-25,45-46H2,1-4H3,(H2,47,57)(H,48,58)(H,49,63)(H,50,62)(H,51,60)(H,52,59)(H,53,61)(H,55,56)/t30-,31-,32-,33-,34-,35-,36-/m0/s1 LNROMWNRSHQHCU-QJCLFNHPSA-N 50009195 3-(2-{2-[6-Amino-2-(2-{2-[2-amino-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyrylamino}-3-phenyl-propionylamino)-hexanoylamino]-4-methyl-pentanoylamino}-4-methylsulfanyl-butyrylamino)-succinamic acid::CHEMBL297998 Mu-type opioid receptor Cavia cutleri 7500 ChEMBL 10.1021/jm00109a019 10.7270/Q2XW4KCF 1851843 Salvadori, S; Marastoni, M; Balboni, G; Borea, PA; Morari, M; Tomatis, R University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009195&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44290647 103922252 CHEMBL297998 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033761 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C37H52N8O10/c1-19(2)30(36(54)40-18-28(39)47)45-37(55)31(20(3)4)44-35(53)27(17-29(48)49)43-34(52)26(16-22-9-7-6-8-10-22)42-32(50)21(5)41-33(51)25(38)15-23-11-13-24(46)14-12-23/h6-14,19-21,25-27,30-31,46H,15-18,38H2,1-5H3,(H2,39,47)(H,40,54)(H,41,51)(H,42,50)(H,43,52)(H,44,53)(H,45,55)(H,48,49)/t21-,25-,26-,27-,30-,31-/m0/s1 CJAORFIPPWIGPG-PKNMDTBHSA-N 50009142 (S)-3-((S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::3-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::3-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid (deltorphin C)::3-[1-[1-[1-amino-2-(4-hydroxyphenyl)-(1S)-ethylcarboxamido]-(1S)-ethylcarboxamido]-2-phenyl-(1S)-ethylcarboxamido]-3-[1-[1-carbamoylmethylcarbamoyl-2-methyl-(1S)-propylcarbamoyl]-2-methyl-(1S)-propylcarbamoyl]propanoic acid::CHEMBL281140::Tyr-D-Ala-Phe-Asp-Val-Val-Gly-NH2 Mu-type opioid receptor Cavia cutleri 420 ChEMBL 10.1021/jm00109a019 10.7270/Q2XW4KCF 1851843 Salvadori, S; Marastoni, M; Balboni, G; Borea, PA; Morari, M; Tomatis, R University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009142&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14840430 103922199 CHEMBL281140 ZINC95608444 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033763 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(O)=O InChI=1S/C38H53N7O11/c1-20(2)31(37(55)40-19-30(49)50)45-38(56)32(21(3)4)44-35(53)27(15-16-29(47)48)42-36(54)28(18-23-9-7-6-8-10-23)43-33(51)22(5)41-34(52)26(39)17-24-11-13-25(46)14-12-24/h6-14,20-22,26-28,31-32,46H,15-19,39H2,1-5H3,(H,40,55)(H,41,52)(H,42,54)(H,43,51)(H,44,53)(H,45,56)(H,47,48)(H,49,50)/t22-,26-,27-,28-,31-,32-/m0/s1 FWGXLJYMZWCJJV-LJXGPVSSSA-N 50009185 4-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-4-{1-[1-(carboxymethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propylcarbamoyl}-butyric acid::CHEMBL296603::Tyr-DAla-Phe-Glu-Val-Val-Gly-NH2 Mu-type opioid receptor Cavia cutleri 9000 ChEMBL 10.1021/jm00109a019 10.7270/Q2XW4KCF 1851843 Salvadori, S; Marastoni, M; Balboni, G; Borea, PA; Morari, M; Tomatis, R University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009185 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009185&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9875567 103922242 CHEMBL296603 ZINC95609693 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033764 CSCC[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(O)=O InChI=1S/C44H62N10O10S2/c1-25(2)18-33(41(60)50-32(15-17-66-4)40(59)54-36(44(63)64)22-37(46)56)51-43(62)35(21-28-23-47-24-48-28)53-42(61)34(20-26-8-6-5-7-9-26)52-39(58)31(14-16-65-3)49-38(57)30(45)19-27-10-12-29(55)13-11-27/h5-13,23-25,30-36,55H,14-22,45H2,1-4H3,(H2,46,56)(H,47,48)(H,49,57)(H,50,60)(H,51,62)(H,52,58)(H,53,61)(H,54,59)(H,63,64)/t30-,31-,32-,33-,34-,35-,36-/m0/s1 JQANFDBJZOIYMB-QJCLFNHPSA-N 50009181 2-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyrylamino}-3-phenyl-propionylamino)-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-4-methylsulfanyl-butyrylamino)-succinamic acid::CHEMBL47156 Mu-type opioid receptor Cavia cutleri 350 ChEMBL 10.1021/jm00109a019 10.7270/Q2XW4KCF 1851843 Salvadori, S; Marastoni, M; Balboni, G; Borea, PA; Morari, M; Tomatis, R University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009181&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44290133 103922238 CHEMBL47156 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033766 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O InChI=1S/C40H50N8O10/c1-23(44-37(55)29(41)18-25-9-13-27(50)14-10-25)36(54)46-30(19-24-6-3-2-4-7-24)38(56)43-21-34(52)45-31(20-26-11-15-28(51)16-12-26)40(58)48-17-5-8-33(48)39(57)47-32(22-49)35(42)53/h2-4,6-7,9-16,23,29-33,49-51H,5,8,17-22,41H2,1H3,(H2,42,53)(H,43,56)(H,44,55)(H,45,52)(H,46,54)(H,47,57)/t23-,29+,30+,31+,32+,33+/m1/s1 FHZPGIUBXYVUOY-VWGYHWLBSA-N 50059841 (S)-1-[(S)-2-[2-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid ((S)-1-carbamoyl-2-hydroxy-ethyl)-amide::(S)-2-Amino-N-{(R)-1-[(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethylcarbamoyl]-ethyl}-3-(4-hydroxy-phenyl)-propionamide::1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide::1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide (Dermorphin)::1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide(Dermorphin)::CHEMBL278789::DERMORPHIN::Dermorphin;1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide::H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2::Tyr-Ala-Phe-Gly-Tyr-Pro-Ser::YAFGYPS-NH2 Mu-type opioid receptor Cavia cutleri 1.4 ChEMBL 10.1021/jm00109a019 10.7270/Q2XW4KCF 1851843 Salvadori, S; Marastoni, M; Balboni, G; Borea, PA; Morari, M; Tomatis, R University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059841 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059841&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5485199 103955620 CHEMBL278789 ZINC95548678 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033770 CSCC[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(N)=O InChI=1S/C40H58N8O10S2/c1-23(2)18-31(40(58)46-29(15-17-60-4)38(56)47-30(35(42)53)21-34(51)52)44-33(50)22-43-37(55)32(20-24-8-6-5-7-9-24)48-39(57)28(14-16-59-3)45-36(54)27(41)19-25-10-12-26(49)13-11-25/h5-13,23,27-32,49H,14-22,41H2,1-4H3,(H2,42,53)(H,43,55)(H,44,50)(H,45,54)(H,46,58)(H,47,56)(H,48,57)(H,51,52)/t27-,28-,29-,30-,31-,32-/m0/s1 SZGFQXFUGCPTJD-JNRWAQIZSA-N 50009187 3-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyrylamino}-3-phenyl-propionylamino)-acetylamino]-4-methyl-pentanoylamino}-4-methylsulfanyl-butyrylamino)-succinamic acid::CHEMBL289537 Mu-type opioid receptor Cavia cutleri 100 ChEMBL 10.1021/jm00109a019 10.7270/Q2XW4KCF 1851843 Salvadori, S; Marastoni, M; Balboni, G; Borea, PA; Morari, M; Tomatis, R University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009187 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009187&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44290451 103922244 CHEMBL289537 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033773 CSCC[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(N)=O InChI=1S/C47H64N8O11S2/c1-27(2)22-37(45(64)51-35(19-21-68-4)43(62)52-36(41(49)60)26-40(58)59)53-46(65)39(25-30-12-16-32(57)17-13-30)55-47(66)38(24-28-8-6-5-7-9-28)54-44(63)34(18-20-67-3)50-42(61)33(48)23-29-10-14-31(56)15-11-29/h5-17,27,33-39,56-57H,18-26,48H2,1-4H3,(H2,49,60)(H,50,61)(H,51,64)(H,52,62)(H,53,65)(H,54,63)(H,55,66)(H,58,59)/t33-,34-,35-,36-,37-,38-,39-/m0/s1 IJGPRDDBPJQNHV-ZTYVOHGWSA-N 50009190 3-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyrylamino}-3-phenyl-propionylamino)-3-(4-hydroxy-phenyl)-propionylamino]-4-methyl-pentanoylamino}-4-methylsulfanyl-butyrylamino)-succinamic acid::CHEMBL296749 Mu-type opioid receptor Cavia cutleri 100 ChEMBL 10.1021/jm00109a019 10.7270/Q2XW4KCF 1851843 Salvadori, S; Marastoni, M; Balboni, G; Borea, PA; Morari, M; Tomatis, R University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009190&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44290399 103922247 CHEMBL296749 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033775 CSCC[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C44H61N9O11S2/c1-25(2)18-33(41(60)49-32(15-17-66-4)40(59)53-36(44(63)64)22-37(55)56)50-43(62)35(21-28-23-46-24-47-28)52-42(61)34(20-26-8-6-5-7-9-26)51-39(58)31(14-16-65-3)48-38(57)30(45)19-27-10-12-29(54)13-11-27/h5-13,23-25,30-36,54H,14-22,45H2,1-4H3,(H,46,47)(H,48,57)(H,49,60)(H,50,62)(H,51,58)(H,52,61)(H,53,59)(H,55,56)(H,63,64)/t30-,31-,32-,33-,34-,35-,36-/m0/s1 MYTAWDDCNSLHLR-QJCLFNHPSA-N 50009194 2-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyrylamino}-3-phenyl-propionylamino)-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-4-methylsulfanyl-butyrylamino)-succinic acid::CHEMBL45308 Mu-type opioid receptor Cavia cutleri 6000 ChEMBL 10.1021/jm00109a019 10.7270/Q2XW4KCF 1851843 Salvadori, S; Marastoni, M; Balboni, G; Borea, PA; Morari, M; Tomatis, R University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009194 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009194&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44290398 103922251 CHEMBL45308 C02715 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033776 CC[C@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCSC)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O InChI=1S/C44H64N10O8S2/c1-6-32(38(46)56)49-40(58)34(17-19-64-5)51-42(60)35(20-26(2)3)52-44(62)37(23-29-24-47-25-48-29)54-43(61)36(22-27-10-8-7-9-11-27)53-41(59)33(16-18-63-4)50-39(57)31(45)21-28-12-14-30(55)15-13-28/h7-15,24-26,31-37,55H,6,16-23,45H2,1-5H3,(H2,46,56)(H,47,48)(H,49,58)(H,50,57)(H,51,60)(H,52,62)(H,53,59)(H,54,61)/t31-,32-,33-,34-,35-,36-,37-/m0/s1 NOWZWSKKEBODGT-PEAOEFARSA-N 50009198 2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyrylamino}-3-phenyl-propionylamino)-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoic acid [1-(1-carbamoyl-propylcarbamoyl)-3-methylsulfanyl-propyl]-amide::CHEMBL297059 Mu-type opioid receptor Cavia cutleri 300 ChEMBL 10.1021/jm00109a019 10.7270/Q2XW4KCF 1851843 Salvadori, S; Marastoni, M; Balboni, G; Borea, PA; Morari, M; Tomatis, R University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009198 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009198&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44290134 103922255 CHEMBL297059 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033777 CSCC[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(N)=O InChI=1S/C44H63N11O9S2/c1-25(2)18-34(42(62)51-32(15-17-66-4)40(60)52-33(38(47)58)22-37(46)57)53-44(64)36(21-28-23-48-24-49-28)55-43(63)35(20-26-8-6-5-7-9-26)54-41(61)31(14-16-65-3)50-39(59)30(45)19-27-10-12-29(56)13-11-27/h5-13,23-25,30-36,56H,14-22,45H2,1-4H3,(H2,46,57)(H2,47,58)(H,48,49)(H,50,59)(H,51,62)(H,52,60)(H,53,64)(H,54,61)(H,55,63)/t30-,31-,32-,33-,34-,35-,36-/m0/s1 WGWQXWVBUHKAKM-QJCLFNHPSA-N 50009182 2-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyrylamino}-3-phenyl-propionylamino)-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-4-methylsulfanyl-butyrylamino)-succinamide::CHEMBL297567 Mu-type opioid receptor Cavia cutleri 245 ChEMBL 10.1021/jm00109a019 10.7270/Q2XW4KCF 1851843 Salvadori, S; Marastoni, M; Balboni, G; Borea, PA; Morari, M; Tomatis, R University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009182 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009182&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44290400 103922239 CHEMBL297567 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033778 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(N)=O InChI=1S/C35H49N7O9/c1-18(2)28(30(37)46)41-35(51)29(19(3)4)42-34(50)26(17-27(44)45)40-33(49)25(16-21-9-7-6-8-10-21)39-31(47)20(5)38-32(48)24(36)15-22-11-13-23(43)14-12-22/h6-14,18-20,24-26,28-29,43H,15-17,36H2,1-5H3,(H2,37,46)(H,38,48)(H,39,47)(H,40,49)(H,41,51)(H,42,50)(H,44,45)/t20-,24-,25-,26-,28-,29-/m0/s1 PMUXTGHSDSKBOU-XVDCOPAKSA-N 50009192 3-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-[1-(1-carbamoyl-2-methyl-propylcarbamoyl)-2-methyl-propyl]-succinamic acid::CHEMBL295076 Mu-type opioid receptor Cavia cutleri 320 ChEMBL 10.1021/jm00109a019 10.7270/Q2XW4KCF 1851843 Salvadori, S; Marastoni, M; Balboni, G; Borea, PA; Morari, M; Tomatis, R University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009192 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009192&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44290135 103922249 CHEMBL295076 ZINC29399663 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033782 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C38H54N8O10/c1-20(2)31(37(55)41-19-29(40)48)46-38(56)32(21(3)4)45-35(53)27(15-16-30(49)50)43-36(54)28(18-23-9-7-6-8-10-23)44-33(51)22(5)42-34(52)26(39)17-24-11-13-25(47)14-12-24/h6-14,20-22,26-28,31-32,47H,15-19,39H2,1-5H3,(H2,40,48)(H,41,55)(H,42,52)(H,43,54)(H,44,51)(H,45,53)(H,46,56)(H,49,50)/t22-,26-,27-,28-,31-,32-/m0/s1 NUNBRHVOPFWRRG-LJXGPVSSSA-N 50009193 (S)-4-((S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-4-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propylcarbamoyl}-butyric acid::(S)-5-((S)-1-((S)-1-(2-amino-2-oxoethylamino)-3-methyl-1-oxobutan-2-ylamino)-3-methyl-1-oxobutan-2-ylamino)-4-((S)-2-((R)-2-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)propanamido)-3-phenylpropanamido)-5-oxopentanoic acid::4-(2-{2-[(2-Amino-6-hydroxy-1,2,3,4-tetrahydro-naphthalene-2-carbonyl)-amino]-propionylamino}-3-phenyl-propionylamino)-4-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-butylcarbamoyl]-2-methyl-butylcarbamoyl}-butyric acid::4-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-4-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propylcarbamoyl}-butyric acid::CHEMBL29078::Tyr-Ala-Phe-Asp-Val-Val-Gly::Tyr-D-Ala-Phe-Glu-Val-Val-Gly-NH2 Mu-type opioid receptor Cavia cutleri 5200 ChEMBL 10.1021/jm00109a019 10.7270/Q2XW4KCF 1851843 Salvadori, S; Marastoni, M; Balboni, G; Borea, PA; Morari, M; Tomatis, R University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009193 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009193&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14840431 103922250 CHEMBL29078 ZINC95608653 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033785 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 38 ChEMBL 10.1021/jm00109a019 10.7270/Q2XW4KCF 1851843 Salvadori, S; Marastoni, M; Balboni, G; Borea, PA; Morari, M; Tomatis, R University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033786 CSCC[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(N)=O InChI=1S/C44H62N10O10S2/c1-25(2)18-34(42(62)50-32(15-17-66-4)40(60)51-33(38(46)58)22-37(56)57)52-44(64)36(21-28-23-47-24-48-28)54-43(63)35(20-26-8-6-5-7-9-26)53-41(61)31(14-16-65-3)49-39(59)30(45)19-27-10-12-29(55)13-11-27/h5-13,23-25,30-36,55H,14-22,45H2,1-4H3,(H2,46,58)(H,47,48)(H,49,59)(H,50,62)(H,51,60)(H,52,64)(H,53,61)(H,54,63)(H,56,57)/t30-,31-,32-,33-,34-,35-,36-/m0/s1 BHSURCCZOBVHJJ-QJCLFNHPSA-N 50009180 3-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyrylamino}-3-phenyl-propionylamino)-3-(1H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-4-methylsulfanyl-butyrylamino)-succinamic acid::3-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyrylamino}-3-phenyl-propionylamino)-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-4-methylsulfanyl-butyrylamino)-succinamic acid::CHEMBL32202::Tyr-D-Met-Phe-His-Leu-Met-Asp-NH2 Mu-type opioid receptor Cavia cutleri 1900 ChEMBL 10.1021/jm00109a019 10.7270/Q2XW4KCF 1851843 Salvadori, S; Marastoni, M; Balboni, G; Borea, PA; Morari, M; Tomatis, R University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009180 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009180&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14504437 103922237 CHEMBL32202 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033787 CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O InChI=1S/C30H40N6O8/c1-16(2)25(26(32)40)36-30(44)23(15-24(38)39)35-29(43)22(14-18-7-5-4-6-8-18)34-27(41)17(3)33-28(42)21(31)13-19-9-11-20(37)12-10-19/h4-12,16-17,21-23,25,37H,13-15,31H2,1-3H3,(H2,32,40)(H,33,42)(H,34,41)(H,35,43)(H,36,44)(H,38,39)/t17-,21-,22-,23-,25-/m0/s1 AZBYBIVLEPNUQU-YXAWXADKSA-N 50009189 3-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-(1-carbamoyl-2-methyl-propyl)-succinamic acid::CHEMBL294982 Mu-type opioid receptor Cavia cutleri 650 ChEMBL 10.1021/jm00109a019 10.7270/Q2XW4KCF 1851843 Salvadori, S; Marastoni, M; Balboni, G; Borea, PA; Morari, M; Tomatis, R University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009189 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009189&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44290468 103922246 CHEMBL294982 ZINC29402523 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033789 C[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(O)=O)C(N)=O InChI=1S/C25H31N5O7/c1-14(28-24(36)18(26)11-16-7-9-17(31)10-8-16)23(35)30-20(12-15-5-3-2-4-6-15)25(37)29-19(22(27)34)13-21(32)33/h2-10,14,18-20,31H,11-13,26H2,1H3,(H2,27,34)(H,28,36)(H,29,37)(H,30,35)(H,32,33)/t14-,18-,19-,20-/m0/s1 AAVSVNSRXLRHJZ-DSYPUSFNSA-N 50009191 3-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-succinamic acid::CHEMBL44172 Mu-type opioid receptor Cavia cutleri 160 ChEMBL 10.1021/jm00109a019 10.7270/Q2XW4KCF 1851843 Salvadori, S; Marastoni, M; Balboni, G; Borea, PA; Morari, M; Tomatis, R University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009191&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44290469 103922248 CHEMBL44172 ZINC29402024 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033809 Oc1ccc2CC3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=CC[C@@]35O)c1c[nH]c2ccccc12 InChI=1S/C28H28N2O3/c31-22-8-7-17-13-23-28(32)10-9-19(20-14-29-21-4-2-1-3-18(20)21)26-27(28,24(17)25(22)33-26)11-12-30(23)15-16-5-6-16/h1-4,7-9,14,16,23,26,29,31-32H,5-6,10-13,15H2/t23?,26-,27-,28+/m0/s1 KNLMNSUTXWVHPN-GDOYDIOZSA-N 50009222 4-cyclopropylmethyl-14-(1H-3-indolyl)-(1S,13S,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,14-tetraene-10,17-diol Mu-type opioid receptor Cavia cutleri 0.630 ChEMBL 10.1021/jm00109a027 10.7270/Q2T43TPG 1851846 Portoghese, PS; Nagase, H; MaloneyHuss, KE; Lin, CE; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009222&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44292852 103922279 ZINC13821972 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033817 Oc1ccc2CC3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1oc2ccccc2c1C[C@@]35O InChI=1S/C26H25NO4/c28-18-8-7-15-11-20-26(29)12-17-16-3-1-2-4-19(16)30-22(17)24-25(26,21(15)23(18)31-24)9-10-27(20)13-14-5-6-14/h1-4,7-8,14,20,24,28-29H,5-6,9-13H2/t20?,24-,25-,26+/m0/s1 ZHVWWEYETMPAMX-OOGIKFLQSA-N 50006947 22-cyclopropylmethyl-(1S,2S,13R)-11,14-dioxa-22-azaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaene-2,16-diol::22-cyclopropylmethyl-11,14-dioxa-22-azaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaene-2,16-diol Mu-type opioid receptor Cavia cutleri 19 ChEMBL 10.1021/jm00110a001 10.7270/Q2DZ08XD 1648136 Portoghese, PS University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50006947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50006947&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 13994399 103920236 ZINC03874478 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033818 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)C(C)(C)NC(=O)C(C)(C)NC(=O)[C@H](Cc1ccc(O)cc1)N(CC=C)CC=C)C(O)=O InChI=1S/C38H53N5O7/c1-9-20-43(21-10-2)31(24-27-16-18-28(44)19-17-27)33(46)41-38(7,8)36(50)42-37(5,6)35(49)40-29(23-26-14-12-11-13-15-26)32(45)39-30(34(47)48)22-25(3)4/h9-19,25,29-31,44H,1-2,20-24H2,3-8H3,(H,39,45)(H,40,49)(H,41,46)(H,42,50)(H,47,48)/t29-,30-,31-/m0/s1 XUWLAGNFLUARAN-CHQNGUEUSA-N 50006946 2-[2-(2-{2-[2-Diallylamino-3-(4-hydroxy-phenyl)-propionylamino]-2-methyl-propionylamino}-2-methyl-propionylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::CHEMBL47545::ICI-174864 Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm00110a001 10.7270/Q2DZ08XD 1648136 Portoghese, PS University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50006946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50006946&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44149909 103920235 CHEMBL47545 ZINC29402878 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033821 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1 DQCKKXVULJGBQN-XFWGSAIBSA-N 60212 (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::MLS000069607::NALTREXONE HYDROCHLORIDE::SMR000058767::US10988481, Compound NTX::US9107954, naltrexone::cid_5485201 Mu-type opioid receptor Cavia cutleri 0.800000 ChEMBL 10.1021/jm00110a001 10.7270/Q2DZ08XD 1648136 Portoghese, PS University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60212&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5360515 252639834 DB00704 C07253 ZINC00001773 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033825 Oc1ccc2C[C@H]3N(CC4CC4)CCC45C(Oc1c24)c1[nH]c2ccccc2c1CC35O InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1 WIYUZYBFCWCCQJ-XEWUMVRVSA-N 21864 (21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.0^{1,13}.0^{2,21}.0^{4,12}.0^{5,10}.0^{19,25}]pentacosa-4(12),5,7,9,15,17,19(25)-heptaene-2,16-diol::(8R)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol::NALTRINDOLE::[3H]-naltrindole Mu-type opioid receptor Cavia cutleri 3.8 ChEMBL 10.1021/jm00110a001 10.7270/Q2DZ08XD 1648136 Portoghese, PS University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21864&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3034754 49700969 ZINC62153992 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033830 C[C@H]([C@H]1NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SSC(C)(C)[C@H](NC1=O)C(O)=O)c1ccccc1 InChI=1S/C31H41N5O7S2/c1-17(19-9-7-6-8-10-19)23-27(40)36-25(29(42)43)31(4,5)45-44-30(2,3)24(28(41)33-16-22(38)34-23)35-26(39)21(32)15-18-11-13-20(37)14-12-18/h6-14,17,21,23-25,37H,15-16,32H2,1-5H3,(H,33,41)(H,34,38)(H,35,39)(H,36,40)(H,42,43)/t17-,21-,23+,24+,25+/m0/s1 VPKHEHMSYIDIAS-CTHNSQKRSA-N 50453051 CHEMBL2115465 Mu-type opioid receptor Cavia cutleri 166000 ChEMBL 10.1021/jm00110a010 10.7270/Q21N81QB 1648137 Hruby, VJ; Toth, G; Gehrig, CA; Kao, LF; Knapp, R; Lui, GK; Yamamura, HI; Kramer, TH; Davis, P; Burks, TF University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453051&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71452808 225145828 CHEMBL2115465 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033831 C[C@H]([C@H]1NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SSC(C)(C)[C@H](NC1=O)C(O)=O)c1ccc(cc1)[N+]([O-])=O InChI=1S/C31H40N6O9S2/c1-16(18-8-10-19(11-9-18)37(45)46)23-27(41)36-25(29(43)44)31(4,5)48-47-30(2,3)24(28(42)33-15-22(39)34-23)35-26(40)21(32)14-17-6-12-20(38)13-7-17/h6-13,16,21,23-25,38H,14-15,32H2,1-5H3,(H,33,42)(H,34,39)(H,35,40)(H,36,41)(H,43,44)/t16-,21-,23+,24+,25+/m0/s1 YOHHACNTFXDZSG-NAACQRFPSA-N 50453050 CHEMBL2115466 Mu-type opioid receptor Cavia cutleri 12300 ChEMBL 10.1021/jm00110a010 10.7270/Q21N81QB 1648137 Hruby, VJ; Toth, G; Gehrig, CA; Kao, LF; Knapp, R; Lui, GK; Yamamura, HI; Kramer, TH; Davis, P; Burks, TF University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453050 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453050&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71461733 225145827 CHEMBL2115466 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033832 CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23-,24-/m0/s1 MCMMCRYPQBNCPH-DVKRWUGUSA-N 50001683 13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid::7-Benzyl-10-{[3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL294616::DPDPE Mu-type opioid receptor Cavia cutleri 7300 ChEMBL 10.1021/jm00110a010 10.7270/Q21N81QB 1648137 Hruby, VJ; Toth, G; Gehrig, CA; Kao, LF; Knapp, R; Lui, GK; Yamamura, HI; Kramer, TH; Davis, P; Burks, TF University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001683&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299404 103916113 CHEMBL294616 ZINC27520031 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033844 C[C@@H]([C@H]1NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SSC(C)(C)[C@H](NC1=O)C(O)=O)c1ccccc1 InChI=1S/C31H41N5O7S2/c1-17(19-9-7-6-8-10-19)23-27(40)36-25(29(42)43)31(4,5)45-44-30(2,3)24(28(41)33-16-22(38)34-23)35-26(39)21(32)15-18-11-13-20(37)14-12-18/h6-14,17,21,23-25,37H,15-16,32H2,1-5H3,(H,33,41)(H,34,38)(H,35,39)(H,36,40)(H,42,43)/t17-,21+,23-,24-,25-/m1/s1 VPKHEHMSYIDIAS-CKRZHRKOSA-N 50453048 CHEMBL2115042 Mu-type opioid receptor Cavia cutleri 48300 ChEMBL 10.1021/jm00110a010 10.7270/Q21N81QB 1648137 Hruby, VJ; Toth, G; Gehrig, CA; Kao, LF; Knapp, R; Lui, GK; Yamamura, HI; Kramer, TH; Davis, P; Burks, TF University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453048&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71450979 225145825 CHEMBL2115042 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033848 C[C@@H]([C@@H]1NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SSC(C)(C)[C@H](NC1=O)C(O)=O)c1ccc(cc1)[N+]([O-])=O InChI=1S/C31H40N6O9S2/c1-16(18-8-10-19(11-9-18)37(45)46)23-27(41)36-25(29(43)44)31(4,5)48-47-30(2,3)24(28(42)33-15-22(39)34-23)35-26(40)21(32)14-17-6-12-20(38)13-7-17/h6-13,16,21,23-25,38H,14-15,32H2,1-5H3,(H,33,42)(H,34,39)(H,35,40)(H,36,41)(H,43,44)/t16-,21+,23+,24-,25-/m1/s1 YOHHACNTFXDZSG-UPNDPRHASA-N 50453049 CHEMBL2115043 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm00110a010 10.7270/Q21N81QB 1648137 Hruby, VJ; Toth, G; Gehrig, CA; Kao, LF; Knapp, R; Lui, GK; Yamamura, HI; Kramer, TH; Davis, P; Burks, TF University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453049 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453049&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71461710 225145826 CHEMBL2115043 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031624 CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)COc1ccccc1 InChI=1S/C19H28N2O2/c1-20(19(22)15-23-16-9-3-2-4-10-16)17-11-5-6-12-18(17)21-13-7-8-14-21/h2-4,9-10,17-18H,5-8,11-15H2,1H3/t17-,18-/m1/s1 RZJGYBAZIAUKGJ-QZTJIDSGSA-N 50018777 CHEMBL556802::N-Methyl-2-phenoxy-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide; hydrochloride, Hydrate Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018777&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380174 103929836 CHEMBL556802 ZINC27978353 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031625 CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)COc1cc(Cl)c(Cl)c(Cl)c1 InChI=1S/C19H25Cl3N2O2/c1-23(16-6-2-3-7-17(16)24-8-4-5-9-24)18(25)12-26-13-10-14(20)19(22)15(21)11-13/h10-11,16-17H,2-9,12H2,1H3/t16-,17-/m1/s1 GQBRYJANYDGUOI-IAGOWNOFSA-N 50018781 CHEMBL557426::N-Methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-2-(3,4,5-trichloro-phenoxy)-acetamide; hydrochloride, Hydrate Mu-type opioid receptor Cavia cutleri 140 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018781 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018781&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380564 103929840 CHEMBL557426 ZINC27900428 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031628 CN(CCc1cccs1)[C@@H]1CCCC[C@H]1N(C)C(=O)Cc1cccc2sccc12 InChI=1S/C24H30N2OS2/c1-25(14-12-19-8-6-15-28-19)21-9-3-4-10-22(21)26(2)24(27)17-18-7-5-11-23-20(18)13-16-29-23/h5-8,11,13,15-16,21-22H,3-4,9-10,12,14,17H2,1-2H3/t21-,22-/m1/s1 CWPJYANXESXODC-FGZHOGPDSA-N 50018779 2-Benzo[b]thiophen-4-yl-N-methyl-N-{2-[methyl-(2-thiophen-2-yl-ethyl)-amino]-cyclohexyl}-acetamide; hydrochloride::CHEMBL536937 Mu-type opioid receptor Cavia cutleri 81 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018779 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018779&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380402 103929838 CHEMBL536937 ZINC27895710 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031629 CN([C@@H]1CCCC[C@H]1N1CCCCCC1)C(=O)COc1cc(Cl)c(Cl)c(Cl)c1Cl InChI=1S/C21H28Cl4N2O2/c1-26(15-8-4-5-9-16(15)27-10-6-2-3-7-11-27)18(28)13-29-17-12-14(22)19(23)21(25)20(17)24/h12,15-16H,2-11,13H2,1H3/t15-,16-/m1/s1 VPLIZQBJXWNKFX-HZPDHXFCSA-N 50018771 CHEMBL535801::N-(2-Azepan-1-yl-cyclohexyl)-N-methyl-2-(2,3,4,5-tetrachloro-phenoxy)-acetamide; hydrochloride Mu-type opioid receptor Cavia cutleri 720 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018771&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380198 103929830 CHEMBL535801 ZINC27899648 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031632 CN([C@@H]1CCCC[C@H]1N1CCCCCCC1)C(=O)COc1cc(Cl)c(Cl)c(Cl)c1 InChI=1S/C22H31Cl3N2O2/c1-26(21(28)15-29-16-13-17(23)22(25)18(24)14-16)19-9-5-6-10-20(19)27-11-7-3-2-4-8-12-27/h13-14,19-20H,2-12,15H2,1H3/t19-,20-/m1/s1 LMGIZTXXHFSYLR-WOJBJXKFSA-N 50018786 CHEMBL538309::N-(2-Azocan-1-yl-cyclohexyl)-N-methyl-2-(3,4,5-trichloro-phenoxy)-acetamide; hydrochloride, Hydrate Mu-type opioid receptor Cavia cutleri 880 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018786&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380472 103929845 CHEMBL538309 ZINC27987528 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031633 CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1cccc2occc12 InChI=1S/C21H28N2O2/c1-22(18-8-2-3-9-19(18)23-12-4-5-13-23)21(24)15-16-7-6-10-20-17(16)11-14-25-20/h6-7,10-11,14,18-19H,2-5,8-9,12-13,15H2,1H3/t18-,19-/m1/s1 HTXMQQXQLBZACS-RTBURBONSA-N 50018762 2-Benzofuran-4-yl-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide; hydrobromide, Hydrate::2-Benzofuran-4-yl-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide; hydrochloride::2-Benzofuran-4-yl-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide; hydrochloride, Hydrate::CHEMBL558608 Mu-type opioid receptor Cavia cutleri 3300 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018762&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14040453 103929821 CHEMBL558608 ZINC00003822 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031635 CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)CCc1c[nH]c2ccccc12 InChI=1S/C22H31N3O/c1-24(20-10-4-5-11-21(20)25-14-6-7-15-25)22(26)13-12-17-16-23-19-9-3-2-8-18(17)19/h2-3,8-9,16,20-21,23H,4-7,10-15H2,1H3/t20-,21-/m1/s1 DFBRXDUAXHPRJM-NHCUHLMSSA-N 50018775 3-(1H-Indol-3-yl)-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-propionamide; hydrochloride, Hydrate::CHEMBL559214 Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018775&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14040467 103929834 CHEMBL559214 ZINC27979097 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031636 CN([C@@H]1CCCC[C@H]1N1CCCCC1)C(=O)Cc1cccc2sccc12 InChI=1S/C22H30N2OS/c1-23(19-9-3-4-10-20(19)24-13-5-2-6-14-24)22(25)16-17-8-7-11-21-18(17)12-15-26-21/h7-8,11-12,15,19-20H,2-6,9-10,13-14,16H2,1H3/t19-,20-/m1/s1 PCSNJPSRIZXIRW-WOJBJXKFSA-N 50018780 2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-piperidin-1-yl-cyclohexyl)-acetamide; hydrochloride::CHEMBL538308 Mu-type opioid receptor Cavia cutleri 2400 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018780 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018780&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 18607187 103929839 CHEMBL538308 ZINC27900436 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031639 CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1cccs1 InChI=1S/C17H26N2OS/c1-18(17(20)13-14-7-6-12-21-14)15-8-2-3-9-16(15)19-10-4-5-11-19/h6-7,12,15-16H,2-5,8-11,13H2,1H3/t15-,16-/m1/s1 CKUZGWDFPOYMNZ-HZPDHXFCSA-N 50018773 CHEMBL535133::N-Methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-2-thiophen-2-yl-acetamide; hydrochloride, Hydrate Mu-type opioid receptor Cavia cutleri 18000 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018773 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018773&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380569 103929832 CHEMBL535133 ZINC06010263 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031640 CN([C@@H]1CCCC[C@H]1N1CCCCCC1)C(=O)Cc1cccc2occc12 InChI=1S/C23H32N2O2/c1-24(23(26)17-18-9-8-12-22-19(18)13-16-27-22)20-10-4-5-11-21(20)25-14-6-2-3-7-15-25/h8-9,12-13,16,20-21H,2-7,10-11,14-15,17H2,1H3/t20-,21-/m1/s1 PHOJLRJBEDGGBH-NHCUHLMSSA-N 50018784 CHEMBL559217::N-(2-Azepan-1-yl-cyclohexyl)-2-benzofuran-4-yl-N-methyl-acetamide; hydrochloride Mu-type opioid receptor Cavia cutleri 3500 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018784&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380333 103929843 CHEMBL559217 ZINC27900002 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031641 CC[C@]12CCN(CC3CC3)C([C@@H]1C)C(=O)c1ccc(O)cc21 InChI=1S/C19H25NO2/c1-3-19-8-9-20(11-13-4-5-13)17(12(19)2)18(22)15-7-6-14(21)10-16(15)19/h6-7,10,12-13,17,21H,3-5,8-9,11H2,1-2H3/t12-,17?,19-/m0/s1 SEJUQQOPVAUETF-BKBNBNODSA-N 50000091 (6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::(6S,11R)-3-Cyclopropylmethyl-9-hydroxy-6,11-dimethyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one (ethylketocyclazocine)::3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one(Ethylketazocine, EKC)::CHEMBL279968::EKC::EKC(-) Mu-type opioid receptor Cavia cutleri 1.7 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000091&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44273397 103914788 CHEMBL279968 ZINC00967957 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031642 CN(CC1CC1)[C@@H]1CCCC[C@H]1N(C)C(=O)Cc1cccc2sccc12 InChI=1S/C22H30N2OS/c1-23(15-16-10-11-16)19-7-3-4-8-20(19)24(2)22(25)14-17-6-5-9-21-18(17)12-13-26-21/h5-6,9,12-13,16,19-20H,3-4,7-8,10-11,14-15H2,1-2H3/t19-,20-/m1/s1 BLQSPWHFSRSTAS-WOJBJXKFSA-N 50018766 2-Benzo[b]thiophen-4-yl-N-[2-(cyclopropylmethyl-methyl-amino)-cyclohexyl]-N-methyl-acetamide; hydrochloride::CHEMBL537165 Mu-type opioid receptor Cavia cutleri 190 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018766&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 13911091 103929825 CHEMBL537165 ZINC27894441 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031644 CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C19H26Cl2N2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17-,18-/m1/s1 VQLPLYSROCPWFF-QZTJIDSGSA-N 50000296 CHEMBL441765::CHEMBL482811::U-50488H::US11492374, ID 1 Mu-type opioid receptor Cavia cutleri 880 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000296&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036289 103914903 73358 CHEMBL482811CHEMBL441765 1654 C11796 ZINC00643032 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031656 CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1c[nH]c2ccccc12 InChI=1S/C21H29N3O/c1-23(19-10-4-5-11-20(19)24-12-6-7-13-24)21(25)14-16-15-22-18-9-3-2-8-17(16)18/h2-3,8-9,15,19-20,22H,4-7,10-14H2,1H3/t19-,20-/m1/s1 OWPSQDPQBXUYDT-WOJBJXKFSA-N 50018763 2-(1H-Indol-3-yl)-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide, Hydrate::CHEMBL354548 Mu-type opioid receptor Cavia cutleri 2900 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018763 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018763&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14040447 103929822 CHEMBL354548 ZINC27899300 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031657 CN([C@@H]1CCCC[C@H]1N1CCCCCC1)C(=O)COc1cc(Cl)cc(Cl)c1 InChI=1S/C21H30Cl2N2O2/c1-24(21(26)15-27-18-13-16(22)12-17(23)14-18)19-8-4-5-9-20(19)25-10-6-2-3-7-11-25/h12-14,19-20H,2-11,15H2,1H3/t19-,20-/m1/s1 ZGOCECSZFFUJNG-WOJBJXKFSA-N 50018776 CHEMBL537615::N-(2-Azepan-1-yl-cyclohexyl)-2-(3,5-dichloro-phenoxy)-N-methyl-acetamide; hydrochloride, Hydrate Mu-type opioid receptor Cavia cutleri 7900 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018776 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018776&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380336 103929835 CHEMBL537615 ZINC27897789 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031659 CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)COc1c(Cl)cc(Cl)cc1Cl InChI=1S/C19H25Cl3N2O2/c1-23(16-6-2-3-7-17(16)24-8-4-5-9-24)18(25)12-26-19-14(21)10-13(20)11-15(19)22/h10-11,16-17H,2-9,12H2,1H3/t16-,17-/m1/s1 UPDDIRTYOSMTEI-IAGOWNOFSA-N 50018787 CHEMBL535803::N-Methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-2-(2,4,6-trichloro-phenoxy)-acetamide; hydrochloride Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018787&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380554 103929846 CHEMBL535803 ZINC00833540 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031660 CN([C@H]1CC[C@@]2(CCCO2)C[C@@H]1N1CCCC1)C(=O)Cc1ccccc1 InChI=1S/C22H32N2O2/c1-23(21(25)16-18-8-3-2-4-9-18)19-10-12-22(11-7-15-26-22)17-20(19)24-13-5-6-14-24/h2-4,8-9,19-20H,5-7,10-17H2,1H3/t19-,20-,22-/m0/s1 PGZRDDYTKFZSFR-ONTIZHBOSA-N 21130 N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl)-1-oxaspiro[4.5]decan-8-yl]acetamide::N-methyl-N-(7-(1-pyrrolidinyl)-1-oxaspiro(4,5)dec-8-yl)benzeneacetamide::U-69593::U69,593::[3H]U69593 Mu-type opioid receptor Cavia cutleri 52 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21130&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 105104 49689203 73357 1655 ZINC02517042 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031663 CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)COc1ccc(Cl)c(Cl)c1 InChI=1S/C19H26Cl2N2O2/c1-22(17-6-2-3-7-18(17)23-10-4-5-11-23)19(24)13-25-14-8-9-15(20)16(21)12-14/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17-,18-/m1/s1 BUFGEOWFEWGNLG-QZTJIDSGSA-N 50018764 2-(3,4-Dichloro-phenoxy)-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide; hydrochloride::CHEMBL541619 Mu-type opioid receptor Cavia cutleri 620 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018764 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018764&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 18603270 103929823 CHEMBL541619 ZINC01657337 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033939 Clc1ccc(CC(=O)N2CCc3sccc3C2CN2CCCC2)cc1Cl InChI=1S/C20H22Cl2N2OS/c21-16-4-3-14(11-17(16)22)12-20(25)24-9-5-19-15(6-10-26-19)18(24)13-23-7-1-2-8-23/h3-4,6,10-11,18H,1-2,5,7-9,12-13H2 HTWGECPQHCRGFE-UHFFFAOYSA-N 50007159 2-(3,4-Dichloro-phenyl)-1-(4-pyrrolidin-1-ylmethyl-6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)-ethanone;HCl::CHEMBL89307 Mu-type opioid receptor Cavia cutleri 47 ChEMBL 10.1021/jm00112a042 10.7270/Q2CV4GPX 1652025 Vecchietti, V; Clarke, GD; Colle, R; Giardina, G; Petrone, G; Sbacchi, M Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007159 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007159&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15697372 103920442 CHEMBL89307 ZINC13823969 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031666 CN([C@H]1CCCC[C@@H]1N1CCCC1)C(=O)Cc1cccc2sccc12 InChI=1S/C21H28N2OS/c1-22(18-8-2-3-9-19(18)23-12-4-5-13-23)21(24)15-16-7-6-10-20-17(16)11-14-25-20/h6-7,10-11,14,18-19H,2-5,8-9,12-13,15H2,1H3/t18-,19-/m0/s1 SYHJZCCNQDFHJQ-OALUTQOASA-N 50008854 2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide; hydrochloride::CHEMBL543331 Mu-type opioid receptor Cavia cutleri 880 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008854&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9906722 103921955 CHEMBL543331 ZINC03779690 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031667 CN(CCc1ccccc1)[C@@H]1CCCC[C@H]1N(C)C(=O)Cc1cccc2sccc12 InChI=1S/C26H32N2OS/c1-27(17-15-20-9-4-3-5-10-20)23-12-6-7-13-24(23)28(2)26(29)19-21-11-8-14-25-22(21)16-18-30-25/h3-5,8-11,14,16,18,23-24H,6-7,12-13,15,17,19H2,1-2H3/t23-,24-/m1/s1 LXFGBAKZVRFCIT-DNQXCXABSA-N 50018778 2-Benzo[b]thiophen-4-yl-N-methyl-N-[2-(methyl-phenethyl-amino)-cyclohexyl]-acetamide; hydrochloride::CHEMBL558979 Mu-type opioid receptor Cavia cutleri 26 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018778 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018778&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380822 103929837 CHEMBL558979 ZINC27901824 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031668 CCN(CC)[C@@H]1CCCC[C@H]1N(C)C(=O)Cc1cccc2sccc12 InChI=1S/C21H30N2OS/c1-4-23(5-2)19-11-7-6-10-18(19)22(3)21(24)15-16-9-8-12-20-17(16)13-14-25-20/h8-9,12-14,18-19H,4-7,10-11,15H2,1-3H3/t18-,19-/m1/s1 HYDDSIVHZOMESG-RTBURBONSA-N 50018785 2-Benzo[b]thiophen-4-yl-N-(2-diethylamino-cyclohexyl)-N-methyl-acetamide; hydrochloride::CHEMBL536939 Mu-type opioid receptor Cavia cutleri 350 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018785&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380566 103929844 CHEMBL536939 ZINC27900433 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031669 CN(CC=C)[C@@H]1CCCC[C@H]1N(C)C(=O)Cc1cccc2sccc12 InChI=1S/C21H28N2OS/c1-4-13-22(2)18-9-5-6-10-19(18)23(3)21(24)15-16-8-7-11-20-17(16)12-14-25-20/h4,7-8,11-12,14,18-19H,1,5-6,9-10,13,15H2,2-3H3/t18-,19-/m1/s1 OITSYRIFLPQYEH-RTBURBONSA-N 50018783 CHEMBL539582::N-[2-(Allyl-methyl-amino)-cyclohexyl]-2-benzo[b]thiophen-4-yl-N-methyl-acetamide; hydrochloride Mu-type opioid receptor Cavia cutleri 210 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018783 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018783&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 13911095 103929842 CHEMBL539582 ZINC27988020 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031672 CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)COc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O InChI=1S/C20H26F3N3O4/c1-24(17-6-2-3-7-18(17)25-10-4-5-11-25)19(27)13-30-14-8-9-16(26(28)29)15(12-14)20(21,22)23/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17-,18-/m1/s1 QHFMXDHHBZOTRU-QZTJIDSGSA-N 50018772 CHEMBL535130::N-Methyl-2-(4-nitro-3-trifluoromethyl-phenoxy)-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide; hydrochloride, Hydrate Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018772 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018772&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380124 103929831 CHEMBL535130 ZINC27899120 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031673 CN([C@@H]1CCCC[C@H]1N1CCCCCCC1)C(=O)COc1cc(Cl)c(Cl)c(Cl)c1Cl InChI=1S/C22H30Cl4N2O2/c1-27(19(29)14-30-18-13-15(23)20(24)22(26)21(18)25)16-9-5-6-10-17(16)28-11-7-3-2-4-8-12-28/h13,16-17H,2-12,14H2,1H3/t16-,17-/m1/s1 UMIVHOMETMYQEH-IAGOWNOFSA-N 50018767 CHEMBL535581::N-(2-Azocan-1-yl-cyclohexyl)-N-methyl-2-(2,3,4,5-tetrachloro-phenoxy)-acetamide; hydrochloride, Hydrate Mu-type opioid receptor Cavia cutleri 3600 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018767 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018767&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380129 103929826 CHEMBL535581 ZINC27899515 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031675 CN([C@@H]1CCCC[C@H]1N1CCCCCC1)C(=O)COc1cc(C)c(Cl)c(C)c1 InChI=1S/C23H35ClN2O2/c1-17-14-19(15-18(2)23(17)24)28-16-22(27)25(3)20-10-6-7-11-21(20)26-12-8-4-5-9-13-26/h14-15,20-21H,4-13,16H2,1-3H3/t20-,21-/m1/s1 BVRSJGBADZRPEP-NHCUHLMSSA-N 50018768 CHEMBL556957::N-(2-Azepan-1-yl-cyclohexyl)-2-(4-chloro-3,5-dimethyl-phenoxy)-N-methyl-acetamide; hydrochloride Mu-type opioid receptor Cavia cutleri 460 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018768 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018768&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380126 103929827 CHEMBL556957 ZINC27899123 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031679 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 1.8 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031687 CN([C@H]1CC[C@@]2(CCCO2)C[C@@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C22H30Cl2N2O2/c1-25(21(27)14-16-5-6-17(23)18(24)13-16)19-7-9-22(8-4-12-28-22)15-20(19)26-10-2-3-11-26/h5-6,13,19-20H,2-4,7-12,14-15H2,1H3/t19-,20-,22-/m0/s1 NYKCGQQJNVPOLU-ONTIZHBOSA-N 83436 2-(3,4-dichlorophenyl)-N-methyl-N-[(5R,7S,8S)-7-(1-pyrrolidinyl)-1-oxaspiro[4.5]decan-8-yl]acetamide;methanesulfonic acid::2-(3,4-dichlorophenyl)-N-methyl-N-[(5R,7S,8S)-7-pyrrolidin-1-yl-1-oxaspiro[4.5]decan-8-yl]acetamide;methanesulfonic acid::2-(3,4-dichlorophenyl)-N-methyl-N-[(5R,7S,8S)-7-pyrrolidin-1-yl-1-oxaspiro[4.5]decan-8-yl]ethanamide;methanesulfonic acid::2-(3,4-dichlorophenyl)-N-methyl-N-[(5R,7S,8S)-7-pyrrolidino-1-oxaspiro[4.5]decan-8-yl]acetamide;mesylic acid::MLS002153429::SMR000326825::Spiradoline::U-62066::cid_55651 Mu-type opioid receptor Cavia cutleri 6400 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=83436 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=83436&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 55652 252658631 ZINC32963898 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031688 CN([C@@H]1CCCC[C@H]1N1CCCCCC1)C(=O)Cc1cccc2sccc12 InChI=1S/C23H32N2OS/c1-24(23(26)17-18-9-8-12-22-19(18)13-16-27-22)20-10-4-5-11-21(20)25-14-6-2-3-7-15-25/h8-9,12-13,16,20-21H,2-7,10-11,14-15,17H2,1H3/t20-,21-/m1/s1 KDMKJISVOZNWDJ-NHCUHLMSSA-N 50018788 CHEMBL537169::N-(2-Azepan-1-yl-cyclohexyl)-2-benzo[b]thiophen-4-yl-N-methyl-acetamide; hydrochloride Mu-type opioid receptor Cavia cutleri 810 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018788&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380791 103929847 CHEMBL537169 ZINC27983928 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031691 CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)COc1ccc(Cl)cc1 InChI=1S/C19H27ClN2O2/c1-21(19(23)14-24-16-10-8-15(20)9-11-16)17-6-2-3-7-18(17)22-12-4-5-13-22/h8-11,17-18H,2-7,12-14H2,1H3/t17-,18-/m1/s1 MGFYCLMWDMGUQD-QZTJIDSGSA-N 50018774 2-(4-Chloro-phenoxy)-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide; hydrochloride, Hydrate::CHEMBL534684 Mu-type opioid receptor Cavia cutleri 2000 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018774&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 13711375 103929833 CHEMBL534684 ZINC27899127 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50031692 CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)COc1c(Cl)cccc1Cl InChI=1S/C19H26Cl2N2O2/c1-22(16-9-2-3-10-17(16)23-11-4-5-12-23)18(24)13-25-19-14(20)7-6-8-15(19)21/h6-8,16-17H,2-5,9-13H2,1H3/t16-,17-/m1/s1 QXOXWUJXNQZXSV-IAGOWNOFSA-N 50018765 2-(2,6-Dichloro-phenoxy)-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide; hydrochloride, Hydrate::CHEMBL556547 Mu-type opioid receptor Cavia cutleri 4000 ChEMBL 10.1021/jm00399a025 10.7270/Q2R78FSK 2832603 Clark, CR; Halfpenny, PR; Hill, RG; Horwell, DC; Hughes, J; Jarvis, TC; Rees, DC; Schofield, D Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018765 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018765&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 18603262 103929824 CHEMBL556547 ZINC27887835 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032924 Cn1c2[C@@H]3Oc4c5c(CC6N(CC7CC7)CC[C@@]35[C@@]6(O)Cc2c2ccccc12)ccc4O InChI=1S/C27H28N2O3/c1-28-19-5-3-2-4-17(19)18-13-27(31)21-12-16-8-9-20(30)24-22(16)26(27,25(32-24)23(18)28)10-11-29(21)14-15-6-7-15/h2-5,8-9,15,21,25,30-31H,6-7,10-14H2,1H3/t21?,25-,26-,27+/m0/s1 CRTCCMARDBQOKA-SSNGLDLMSA-N 50013625 22-cyclopropylmethyl-11-methyl-(1S,2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaene-2,16-diol::22-cyclopropylmethyl-11-methyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol(HCl2H2O)::22-cyclopropylmethyl-11-methyl-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaene-2,16-diol Mu-type opioid receptor Cavia cutleri 14 ChEMBL 10.1021/jm00168a028 10.7270/Q27P9003 2160538 Portoghese, PS; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013625 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013625&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44292630 103925722 ZINC13821974 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032927 COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2ccccc2c1C[C@@]35O InChI=1S/C27H28N2O3/c1-31-20-9-8-16-12-21-27(30)13-18-17-4-2-3-5-19(17)28-23(18)25-26(27,22(16)24(20)32-25)10-11-29(21)14-15-6-7-15/h2-5,8-9,15,21,25,28,30H,6-7,10-14H2,1H3/t21-,25+,26+,27-/m1/s1 HKUIBYDTKWHKJU-NVSKSXHLSA-N 50262499 (5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro-4,5-epoxy-3-methoxy-indolo[2',3':6,7]morphinan-14-ol::22-cyclopropylmethyl-16-methoxy-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaen-2-ol(HCl1.5H2O)::CHEMBL514693 Mu-type opioid receptor Cavia cutleri 550 ChEMBL 10.1021/jm00168a028 10.7270/Q27P9003 2160538 Portoghese, PS; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50262499 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50262499&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44578135 104111161 CHEMBL514693 ZINC03808807 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032936 Oc1ccc2CC3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2ccc(F)cc2c1C[C@@]35O InChI=1S/C26H25FN2O3/c27-15-4-5-18-16(10-15)17-11-26(31)20-9-14-3-6-19(30)23-21(14)25(26,24(32-23)22(17)28-18)7-8-29(20)12-13-1-2-13/h3-6,10,13,20,24,28,30-31H,1-2,7-9,11-12H2/t20?,24-,25-,26+/m0/s1 WGXUQUPBNGMMPM-OOGIKFLQSA-N 50013624 22-cyclopropylmethyl-7-fluoro-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol(HCl.1.5H2O)::22-cyclopropylmethyl-7-fluoro-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaene-2,16-diol Mu-type opioid receptor Cavia cutleri 1.7 ChEMBL 10.1021/jm00168a028 10.7270/Q27P9003 2160538 Portoghese, PS; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013624 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013624&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44292764 103925721 ZINC26675145 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032940 Oc1ccc2C[C@H]3N(CC4CC4)CCC45C(Oc1c24)c1[nH]c2ccccc2c1CC35O InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1 WIYUZYBFCWCCQJ-XEWUMVRVSA-N 21864 (21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.0^{1,13}.0^{2,21}.0^{4,12}.0^{5,10}.0^{19,25}]pentacosa-4(12),5,7,9,15,17,19(25)-heptaene-2,16-diol::(8R)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol::NALTRINDOLE::[3H]-naltrindole Mu-type opioid receptor Cavia cutleri 3.8 ChEMBL 10.1021/jm00168a028 10.7270/Q27P9003 2160538 Portoghese, PS; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21864&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3034754 49700969 ZINC62153992 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032961 Oc1ccc2CC3N(CC=C)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2ccccc2c1C[C@@]35O InChI=1S/C25H24N2O3/c1-2-10-27-11-9-24-20-14-7-8-18(28)22(20)30-23(24)21-16(13-25(24,29)19(27)12-14)15-5-3-4-6-17(15)26-21/h2-8,19,23,26,28-29H,1,9-13H2/t19?,23-,24-,25+/m0/s1 VHOJNKFFCXAXME-DYZJZLFBSA-N 50013621 22-allyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol Mu-type opioid receptor Cavia cutleri 104 ChEMBL 10.1021/jm00168a028 10.7270/Q27P9003 2160538 Portoghese, PS; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013621 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013621&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44292644 103925718 ZINC29408078 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032968 Oc1ccc2CC3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1c(C[C@@]35O)c2ccccc2n1-c1ccccc1 InChI=1S/C32H30N2O3/c35-25-13-12-20-16-26-32(36)17-23-22-8-4-5-9-24(22)34(21-6-2-1-3-7-21)28(23)30-31(32,27(20)29(25)37-30)14-15-33(26)18-19-10-11-19/h1-9,12-13,19,26,30,35-36H,10-11,14-18H2/t26?,30-,31-,32+/m0/s1 XZBLPOKMIVGXML-ZCPWPLGKSA-N 50013627 22-cyclopropylmethyl-11-phenyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol(HCl) Mu-type opioid receptor Cavia cutleri 28 ChEMBL 10.1021/jm00168a028 10.7270/Q27P9003 2160538 Portoghese, PS; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013627 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013627&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44292966 103925724 ZINC29405058 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032970 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)Cc1c4[nH]c2ccccc12)ccc5O InChI=1S/C23H22N2O3/c1-25-9-8-22-18-12-6-7-16(26)20(18)28-21(22)19-14(11-23(22,27)17(25)10-12)13-4-2-3-5-15(13)24-19/h2-7,17,21,24,26-27H,8-11H2,1H3/t17-,21+,22+,23-/m1/s1 YQNZUKAKYJMEFE-LMDOGRNLSA-N 50221416 22-methyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol(HCl0.5H2O) (Oxymorphindole, OMI)::22-methyl-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol::CHEMBL401093::OXYMORPHINDOLE Mu-type opioid receptor Cavia cutleri 468 ChEMBL 10.1021/jm00168a028 10.7270/Q27P9003 2160538 Portoghese, PS; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221416 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221416&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5491897 104094073 CHEMBL401093 ZINC05966777 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032975 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1 DQCKKXVULJGBQN-XFWGSAIBSA-N 60212 (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::MLS000069607::NALTREXONE HYDROCHLORIDE::SMR000058767::US10988481, Compound NTX::US9107954, naltrexone::cid_5485201 Mu-type opioid receptor Cavia cutleri 0.800000 ChEMBL 10.1021/jm00168a028 10.7270/Q27P9003 2160538 Portoghese, PS; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60212&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5360515 252639834 DB00704 C07253 ZINC00001773 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032976 COc1cccc2c3C[C@@]4(O)C5Cc6ccc(O)c7O[C@@H](c3[nH]c12)[C@]4(CCN5CC1CC1)c67 InChI=1S/C27H28N2O4/c1-32-19-4-2-3-16-17-12-27(31)20-11-15-7-8-18(30)24-21(15)26(27,9-10-29(20)13-14-5-6-14)25(33-24)23(17)28-22(16)19/h2-4,7-8,14,20,25,28,30-31H,5-6,9-13H2,1H3/t20?,25-,26-,27+/m0/s1 UFSBESMXMNBZHB-WINLFKIGSA-N 50013622 9-methyloxy-22-cyclopropylmethyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol(HCl1.5H2O) Mu-type opioid receptor Cavia cutleri 16 ChEMBL 10.1021/jm00168a028 10.7270/Q27P9003 2160538 Portoghese, PS; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013622 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013622&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44292997 103925719 ZINC29417015 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032982 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)C(C)(C)NC(=O)C(C)(C)NC(=O)[C@H](Cc1ccc(O)cc1)N(CC=C)CC=C)C(O)=O InChI=1S/C38H53N5O7/c1-9-20-43(21-10-2)31(24-27-16-18-28(44)19-17-27)33(46)41-38(7,8)36(50)42-37(5,6)35(49)40-29(23-26-14-12-11-13-15-26)32(45)39-30(34(47)48)22-25(3)4/h9-19,25,29-31,44H,1-2,20-24H2,3-8H3,(H,39,45)(H,40,49)(H,41,46)(H,42,50)(H,47,48)/t29-,30-,31-/m0/s1 XUWLAGNFLUARAN-CHQNGUEUSA-N 50006946 2-[2-(2-{2-[2-Diallylamino-3-(4-hydroxy-phenyl)-propionylamino]-2-methyl-propionylamino}-2-methyl-propionylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::CHEMBL47545::ICI-174864 Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm00168a028 10.7270/Q27P9003 2160538 Portoghese, PS; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50006946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50006946&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44149909 103920235 CHEMBL47545 ZINC29402878 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032983 Oc1ccc2CC3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2c(Br)cccc2c1C[C@@]35O InChI=1S/C26H25BrN2O3/c27-17-3-1-2-15-16-11-26(31)19-10-14-6-7-18(30)23-20(14)25(26,8-9-29(19)12-13-4-5-13)24(32-23)22(16)28-21(15)17/h1-3,6-7,13,19,24,28,30-31H,4-5,8-12H2/t19?,24-,25-,26+/m0/s1 KXQMACNKPIFADJ-VCCHHJRHSA-N 50013623 9-bromo-22-cyclopropylmethyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol Mu-type opioid receptor Cavia cutleri 29 ChEMBL 10.1021/jm00168a028 10.7270/Q27P9003 2160538 Portoghese, PS; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013623 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013623&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44293065 103925720 ZINC29468503 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032986 Oc1ccc2CC3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2c(F)cccc2c1C[C@@]35O InChI=1S/C26H25FN2O3/c27-17-3-1-2-15-16-11-26(31)19-10-14-6-7-18(30)23-20(14)25(26,8-9-29(19)12-13-4-5-13)24(32-23)22(16)28-21(15)17/h1-3,6-7,13,19,24,28,30-31H,4-5,8-12H2/t19?,24-,25-,26+/m0/s1 GKAYFPSXBGBKFN-VCCHHJRHSA-N 50013619 9-fluoro-22-cyclopropylmethyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol(HCl1.5H2O) Mu-type opioid receptor Cavia cutleri 49 ChEMBL 10.1021/jm00168a028 10.7270/Q27P9003 2160538 Portoghese, PS; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013619 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013619&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44293021 103925716 ZINC29409287 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032990 CC(C)(S)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](NC(=O)[C@@H](N)Cc1ccccc1)C(C)(C)S)C(O)=O InChI=1S/C30H41N5O7S2/c1-29(2,43)23(34-25(38)20(31)14-17-8-6-5-7-9-17)27(40)32-16-22(37)33-21(15-18-10-12-19(36)13-11-18)26(39)35-24(28(41)42)30(3,4)44/h5-13,20-21,23-24,36,43-44H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21-,23-,24-/m0/s1 RILFYUXURMDFOY-WMIMKTLMSA-N 50013620 2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-3-mercapto-3-methyl-butyrylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-3-mercapto-3-methyl-butyric acid (DPLPE)::CHEMBL2372782 Mu-type opioid receptor Cavia cutleri 570 ChEMBL 10.1021/jm00168a028 10.7270/Q27P9003 2160538 Portoghese, PS; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013620 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013620&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73348734 103925717 CHEMBL2372782 ZINC29417536 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032999 CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(O)=O InChI=1S/C33H46N6O10/c1-18(2)13-24(32(47)39-28(19(3)41)33(48)49)37-31(46)25(15-21-9-11-22(42)12-10-21)36-27(43)16-35-30(45)26(17-40)38-29(44)23(34)14-20-7-5-4-6-8-20/h4-12,18-19,23-26,28,40-42H,13-17,34H2,1-3H3,(H,35,45)(H,36,43)(H,37,46)(H,38,44)(H,39,47)(H,48,49)/t19-,23+,24+,25+,26+,28+/m1/s1 HMJDTHFFUZCTEX-KXJTVXFKSA-N 50013626 2-{2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-3-hydroxy-propionylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methyl-pentanoylamino}-3-hydroxy-butyric acid (DSLET)::CHEMBL47029 Mu-type opioid receptor Cavia cutleri 59 ChEMBL 10.1021/jm00168a028 10.7270/Q27P9003 2160538 Portoghese, PS; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013626 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013626&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44292854 103925723 CHEMBL47029 ZINC29415610 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50035308 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C37H52N8O10/c1-19(2)30(36(54)40-18-28(39)47)45-37(55)31(20(3)4)44-35(53)27(17-29(48)49)43-34(52)26(16-22-9-7-6-8-10-22)42-32(50)21(5)41-33(51)25(38)15-23-11-13-24(46)14-12-23/h6-14,19-21,25-27,30-31,46H,15-18,38H2,1-5H3,(H2,39,47)(H,40,54)(H,41,51)(H,42,50)(H,43,52)(H,44,53)(H,45,55)(H,48,49)/t21-,25+,26+,27+,30+,31+/m1/s1 CJAORFIPPWIGPG-QXYJMILXSA-N 50001468 (S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::3-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL317956::H-Tyr-D-Ala-Phe-Asp-Val-Val-Gly-NH2::deltorphin C Mu-type opioid receptor Cavia cutleri 2890 ChEMBL 10.1021/jm00027a017 10.7270/Q2F47N7P 8289187 Misicka, A; Lipkowski, AW; Horvath, R; Davis, P; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001468&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10055958 103915933 CHEMBL317956 C18097 ZINC95610551 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50035311 CC1(C)SSC[C@H](NC(=O)[C@H](Cc2ccc(F)cc2)NC(=O)CNC(=O)[C@@H]1NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O InChI=1S/C37H43FN6O8S2/c1-37(2)31(44-32(47)26(39)16-22-10-14-25(45)15-11-22)35(50)40-19-30(46)41-27(17-23-8-12-24(38)13-9-23)33(48)43-29(20-53-54-37)34(49)42-28(36(51)52)18-21-6-4-3-5-7-21/h3-15,26-29,31,45H,16-20,39H2,1-2H3,(H,40,50)(H,41,46)(H,42,49)(H,43,48)(H,44,47)(H,51,52)/t26-,27-,28-,29-,31-/m0/s1 ZZJQYPCWCUPXMY-OLAIZJASSA-N 50043725 (S)-2-{[(4R,7S)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-(4-fluoro-benzyl)-14,14-dimethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carbonyl]-amino}-3-phenyl-propionic acid::CHEMBL2372327 Mu-type opioid receptor Cavia cutleri 32 ChEMBL 10.1021/jm00027a018 10.7270/Q2TX3G09 8289188 Bartosz-Bechowski, H; Davis, P; Zalewska, T; Slaninova, J; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043725 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043725&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10056035 103975109 CHEMBL2372327 ZINC95613325 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50035312 CC1(C)SSC[C@H](NC(=O)[C@H](Cc2ccc(Cl)cc2)NC(=O)CNC(=O)[C@@H]1NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O InChI=1S/C37H43ClN6O8S2/c1-37(2)31(44-32(47)26(39)16-22-10-14-25(45)15-11-22)35(50)40-19-30(46)41-27(17-23-8-12-24(38)13-9-23)33(48)43-29(20-53-54-37)34(49)42-28(36(51)52)18-21-6-4-3-5-7-21/h3-15,26-29,31,45H,16-20,39H2,1-2H3,(H,40,50)(H,41,46)(H,42,49)(H,43,48)(H,44,47)(H,51,52)/t26-,27-,28-,29-,31-/m0/s1 XXAWIFPTSDMCQN-OLAIZJASSA-N 50043720 (S)-2-{[(4R,7S)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-(4-chloro-benzyl)-14,14-dimethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carbonyl]-amino}-3-phenyl-propionic acid::CHEMBL2372328 Mu-type opioid receptor Cavia cutleri 36 ChEMBL 10.1021/jm00027a018 10.7270/Q2TX3G09 8289188 Bartosz-Bechowski, H; Davis, P; Zalewska, T; Slaninova, J; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043720 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043720&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10373147 103975104 CHEMBL2372328 ZINC95541978 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50035314 CC1(C)SSC[C@H](NC(=O)[C@H](Cc2ccc(Br)cc2)NC(=O)CNC(=O)[C@@H]1NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O InChI=1S/C37H43BrN6O8S2/c1-37(2)31(44-32(47)26(39)16-22-10-14-25(45)15-11-22)35(50)40-19-30(46)41-27(17-23-8-12-24(38)13-9-23)33(48)43-29(20-53-54-37)34(49)42-28(36(51)52)18-21-6-4-3-5-7-21/h3-15,26-29,31,45H,16-20,39H2,1-2H3,(H,40,50)(H,41,46)(H,42,49)(H,43,48)(H,44,47)(H,51,52)/t26-,27-,28-,29-,31-/m0/s1 LLSAWIGHKLJTIU-OLAIZJASSA-N 50043721 (S)-2-{[(4R,7S)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-(4-bromo-benzyl)-14,14-dimethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carbonyl]-amino}-3-phenyl-propionic acid::CHEMBL2372314 Mu-type opioid receptor Cavia cutleri 120 ChEMBL 10.1021/jm00027a018 10.7270/Q2TX3G09 8289188 Bartosz-Bechowski, H; Davis, P; Zalewska, T; Slaninova, J; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043721 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043721&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11766061 103975105 CHEMBL2372314 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50035362 CCCCN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)Cc1c2C[C@@]3(O)[C@H]6Cc7ccc(O)c8O[C@@H](c2[nH]c41)[C@]3(CCN6CC1CC1)c78)ccc5O InChI=1S/C40H45N3O6/c1-2-3-12-42-13-10-37-29-21-6-8-25(44)33(29)48-35(37)31-23(17-39(37,46)27(42)15-21)24-18-40(47)28-16-22-7-9-26(45)34-30(22)38(40,36(49-34)32(24)41-31)11-14-43(28)19-20-4-5-20/h6-9,20,27-28,35-36,41,44-47H,2-5,10-19H2,1H3/t27-,28-,35+,36+,37+,38+,39-,40-/m1/s1 QUHICZCAIBKQSC-YAUKWVCOSA-N 50041573 17-(cyclopropylmethyl)-17'-butyl-6,6',7,7'-tetradehydro-4,5:4',5'-diepoxy-6,6'-imino-7,7'-bimorphinan-3,3',14,14'-tetrol::CHEMBL285410 Mu-type opioid receptor Cavia cutleri 73 ChEMBL 10.1021/jm00036a015 10.7270/Q2XP75K7 8182708 Portoghese, PS; Lin, CE; Farouz-Grant, F; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041573&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10416962 103973274 CHEMBL285410 ZINC29252980 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50035367 NCC(=O)NCC(=O)N1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)Cc1c2C[C@@]3(O)[C@H]6Cc7ccc(O)c8O[C@@H](c2[nH]c41)[C@]3(CCN6CC1CC1)c78)ccc5O InChI=1S/C40H43N5O8/c41-15-27(48)42-16-28(49)45-10-8-38-30-20-4-6-24(47)34(30)53-36(38)32-22(14-40(38,51)26(45)12-20)21-13-39(50)25-11-19-3-5-23(46)33-29(19)37(39,35(52-33)31(21)43-32)7-9-44(25)17-18-1-2-18/h3-6,18,25-26,35-36,43,46-47,50-51H,1-2,7-17,41H2,(H,42,48)/t25-,26-,35+,36+,37+,38+,39-,40-/m1/s1 QSSOIVBGIOETKQ-FUCLXHLGSA-N 50041569 17-(cyclopropylmethyl)-17'-aminoethyl-6,6',7,7'-tetradehydro-4,5:4',5'-diepoxy-6,6'-imino-7,7'-bimorphinan-3,3',14,14'-tetrol::CHEMBL285052 Mu-type opioid receptor Cavia cutleri 66 ChEMBL 10.1021/jm00036a015 10.7270/Q2XP75K7 8182708 Portoghese, PS; Lin, CE; Farouz-Grant, F; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041569&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10327545 103973271 CHEMBL285052 ZINC29252040 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50035384 NCCN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)Cc1c2C[C@@]3(O)[C@H]6Cc7ccc(O)c8O[C@@H](c2[nH]c41)[C@]3(CCN6CC1CC1)c78)ccc5O InChI=1S/C38H42N4O6/c39-9-12-41-10-7-35-27-19-3-5-23(43)31(27)47-33(35)29-21(15-37(35,45)25(41)13-19)22-16-38(46)26-14-20-4-6-24(44)32-28(20)36(38,34(48-32)30(22)40-29)8-11-42(26)17-18-1-2-18/h3-6,18,25-26,33-34,40,43-46H,1-2,7-17,39H2/t25-,26-,33+,34+,35+,36+,37-,38-/m1/s1 YUBVMRWUYHONDP-ZQUSMLRHSA-N 50041570 17-(cyclopropylmethyl)-17'-aminoethyl-6,6',7,7'-tetradehydro-4,5:4',5'-diepoxy-6,6'-imino-7,7'-bimorphinan-3,3',14,14'-tetrol::CHEMBL286585 Mu-type opioid receptor Cavia cutleri 46 ChEMBL 10.1021/jm00036a015 10.7270/Q2XP75K7 8182708 Portoghese, PS; Lin, CE; Farouz-Grant, F; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041570&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10078008 103973272 CHEMBL286585 ZINC29307542 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50035389 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2[C@@H]4Oc6c7c(C[C@H]8N(CC9CC9)CC[C@@]47[C@@]8(O)Cc2c1C[C@@]35O)ccc6O InChI=1S/C40H43N3O6/c44-25-7-5-21-13-27-39(46)15-23-24-16-40(47)28-14-22-6-8-26(45)34-30(22)38(40,10-12-43(28)18-20-3-4-20)36(49-34)32(24)41-31(23)35-37(39,29(21)33(25)48-35)9-11-42(27)17-19-1-2-19/h5-8,19-20,27-28,35-36,41,44-47H,1-4,9-18H2/t27-,28-,35+,36+,37+,38+,39-,40-/m1/s1 APSUXPSYBJVPPS-YAUKWVCOSA-N 82551 C18130::CAS_105618-26-6::NOR-BNI (HCI)2::NORBNI Mu-type opioid receptor Cavia cutleri 47 ChEMBL 10.1021/jm00036a015 10.7270/Q2XP75K7 8182708 Portoghese, PS; Lin, CE; Farouz-Grant, F; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82551&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5480230 136350521 C18130 ZINC03995590 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50035390 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2[C@@H]4Oc6c7c(C=C8N(CCNC(=O)OCc9ccccc9)CC[C@@]47[C@@]8(O)Cc2c1C[C@@]35O)ccc6O InChI=1S/C46H46N4O8/c51-30-10-8-26-18-32-45(54)20-28-29-21-46(55)33-19-27-9-11-31(52)39-35(27)44(46,13-16-50(33)22-24-6-7-24)41(58-39)37(29)48-36(28)40-43(45,34(26)38(30)57-40)12-15-49(32)17-14-47-42(53)56-23-25-4-2-1-3-5-25/h1-5,8-11,18,24,33,40-41,48,51-52,54-55H,6-7,12-17,19-23H2,(H,47,53)/t33-,40+,41+,43+,44+,45-,46-/m1/s1 KMSCRBUSFBVFLD-COTKPVQASA-N 50041568 17-(cyclopropylmethyl)-17'-[2-[(carbobenzyloxy)amino]ethyl]-6,6',7,7'-tetradehydro-4,5:4',5'-diepoxy-6,6'-imino-7,7'-bimorphinan-3,3',14,14'-tetrol::CHEMBL284522 Mu-type opioid receptor Cavia cutleri 70 ChEMBL 10.1021/jm00036a015 10.7270/Q2XP75K7 8182708 Portoghese, PS; Lin, CE; Farouz-Grant, F; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041568&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44283843 103973270 CHEMBL284522 ZINC95542355 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50035392 NC(=N)NCCN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)Cc1c2C[C@@]3(O)[C@H]6Cc7ccc(O)c8O[C@@H](c2[nH]c41)C3(CCN6CC1CC1)c78)ccc5O InChI=1S/C39H44N6O6/c40-35(41)42-9-12-44-10-7-36-27-19-3-5-23(46)31(27)50-33(36)29-21(15-38(36,48)25(44)13-19)22-16-39(49)26-14-20-4-6-24(47)32-28(20)37(39,34(51-32)30(22)43-29)8-11-45(26)17-18-1-2-18/h3-6,18,25-26,33-34,43,46-49H,1-2,7-17H2,(H4,40,41,42)/t25-,26-,33+,34+,36+,37?,38-,39-/m1/s1 UPVIZTSWVQCULU-JOXXKNRASA-N 50041572 17-(cyclopropylmethyl)-17'-(2-guanidinoethyl-6,6',7,7'-tetradehydro-4,5:4',5'-diepoxy-6,6'-imino-7,7'-bimorphinan-3,3',14,14'-tetrol::CHEMBL287750 Mu-type opioid receptor Cavia cutleri 50 ChEMBL 10.1021/jm00036a015 10.7270/Q2XP75K7 8182708 Portoghese, PS; Lin, CE; Farouz-Grant, F; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041572 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041572&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44283842 103973273 CHEMBL287750 ZINC49627295 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50035408 CN([C@H](CN1CCCC1)c1cccc(c1)N=C=S)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C22H23Cl2N3OS/c1-26(22(28)12-16-7-8-19(23)20(24)11-16)21(14-27-9-2-3-10-27)17-5-4-6-18(13-17)25-15-29/h4-8,11,13,21H,2-3,9-10,12,14H2,1H3/t21-/m1/s1 BNAKCEFXXMHXDQ-OAQYLSRUSA-N 50035471 2-(3,4-Dichloro-phenyl)-N-[(S)-1-(3-isothiocyanato-phenyl)-2-pyrrolidin-1-yl-ethyl]-N-methyl-acetamide::CHEMBL38521 Mu-type opioid receptor Cavia cutleri 1799 ChEMBL 10.1021/jm00037a001 10.7270/Q24X56T9 8201586 Chang, AC; Takemori, AE; Portoghese, PS University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035471&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 127914 103943490 CHEMBL38521 ZINC02567731 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032037 CN1CC[C@]23CCCC[C@H]2[C@H]1Cc1ccc(O)cc31 InChI=1S/C17H23NO/c1-18-9-8-17-7-3-2-4-14(17)16(18)10-12-5-6-13(19)11-15(12)17/h5-6,11,14,16,19H,2-4,7-10H2,1H3/t14-,16+,17+/m0/s1 JAQUASYNZVUNQP-USXIJHARSA-N 50017233 CHEMBL592::LEVO-DROMORAN::LEVORPHANOL Mu-type opioid receptor Cavia cutleri 0.600000 ChEMBL 10.1021/jm00126a019 10.7270/Q280536X 2542556 Fujimoto, RA; Boxer, J; Jackson, RH; Simke, JP; Neale, RF; Snowhill, EW; Barbaz, BJ; Williams, M; Sills, MA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017233 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017233&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5359272 103928501 CHEMBL592 DB00854 C08014 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032046 CN([C@H]1CCCC[C@@]11CCCN1C)C(=O)c1ccc(Br)cc1C InChI=1S/C19H27BrN2O/c1-14-13-15(20)8-9-16(14)18(23)22(3)17-7-4-5-10-19(17)11-6-12-21(19)2/h8-9,13,17H,4-7,10-12H2,1-3H3/t17-,19+/m0/s1 FDLBGWVLLWZVNF-PKOBYXMFSA-N 50017078 4-Bromo-2,N-dimethyl-N-(1-methyl-1-aza-spiro[4.5]dec-6-yl)-benzamide::CHEMBL277202 Mu-type opioid receptor Cavia cutleri 21 ChEMBL 10.1021/jm00126a019 10.7270/Q280536X 2542556 Fujimoto, RA; Boxer, J; Jackson, RH; Simke, JP; Neale, RF; Snowhill, EW; Barbaz, BJ; Williams, M; Sills, MA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017078&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14548225 103928406 CHEMBL277202 ZINC28253541 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032047 COc1ccc(cc1)C(=O)N[C@H]1CCCC[C@@]11CCCN1C InChI=1S/C18H26N2O2/c1-20-13-5-12-18(20)11-4-3-6-16(18)19-17(21)14-7-9-15(22-2)10-8-14/h7-10,16H,3-6,11-13H2,1-2H3,(H,19,21)/t16-,18+/m0/s1 GIUMYFRPOGFCAY-FUHWJXTLSA-N 50017066 4-Methoxy-N-(1-methyl-1-aza-spiro[4.5]dec-6-yl)-benzamide; hydrochloride::CHEMBL542564 Mu-type opioid receptor Cavia cutleri 2200 ChEMBL 10.1021/jm00126a019 10.7270/Q280536X 2542556 Fujimoto, RA; Boxer, J; Jackson, RH; Simke, JP; Neale, RF; Snowhill, EW; Barbaz, BJ; Williams, M; Sills, MA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017066&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14548207 103928394 CHEMBL542564 ZINC28257452 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032050 CN1CCC[C@@]11CCCC[C@@H]1NC(=O)c1ccc(F)cc1 InChI=1S/C17H23FN2O/c1-20-12-4-11-17(20)10-3-2-5-15(17)19-16(21)13-6-8-14(18)9-7-13/h6-9,15H,2-5,10-12H2,1H3,(H,19,21)/t15-,17+/m0/s1 WKGBEIYDAYWXTO-DOTOQJQBSA-N 50017073 4-Fluoro-N-(1-methyl-1-aza-spiro[4.5]dec-6-yl)-benzamide::CHEMBL23777 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm00126a019 10.7270/Q280536X 2542556 Fujimoto, RA; Boxer, J; Jackson, RH; Simke, JP; Neale, RF; Snowhill, EW; Barbaz, BJ; Williams, M; Sills, MA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017073&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14548205 103928401 CHEMBL23777 ZINC28257457 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032051 CN([C@H]1CCCC[C@@]11CCCN1C)C(=O)c1ccc(Br)c(Br)c1 InChI=1S/C18H24Br2N2O/c1-21-11-5-10-18(21)9-4-3-6-16(18)22(2)17(23)13-7-8-14(19)15(20)12-13/h7-8,12,16H,3-6,9-11H2,1-2H3/t16-,18+/m0/s1 XHBTZWGPHRHWQZ-FUHWJXTLSA-N 50017059 3,4-Dibromo-N-methyl-N-(1-methyl-1-aza-spiro[4.5]dec-6-yl)-benzamide::CHEMBL279065 Mu-type opioid receptor Cavia cutleri 2 ChEMBL 10.1021/jm00126a019 10.7270/Q280536X 2542556 Fujimoto, RA; Boxer, J; Jackson, RH; Simke, JP; Neale, RF; Snowhill, EW; Barbaz, BJ; Williams, M; Sills, MA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017059 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017059&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14548221 103928387 CHEMBL279065 ZINC28254962 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032055 CN1CCC[C@@]11CCCC[C@@H]1NC(=O)CCc1ccccc1 InChI=1S/C19H28N2O/c1-21-15-7-14-19(21)13-6-5-10-17(19)20-18(22)12-11-16-8-3-2-4-9-16/h2-4,8-9,17H,5-7,10-15H2,1H3,(H,20,22)/t17-,19+/m0/s1 MFFYUKOUECKTPR-PKOBYXMFSA-N 50017067 CHEMBL25386::N-(1-Methyl-1-aza-spiro[4.5]dec-6-yl)-3-phenyl-propionamide Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm00126a019 10.7270/Q280536X 2542556 Fujimoto, RA; Boxer, J; Jackson, RH; Simke, JP; Neale, RF; Snowhill, EW; Barbaz, BJ; Williams, M; Sills, MA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017067&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14548211 103928395 CHEMBL25386 ZINC28254527 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032057 CN1CCC[C@@]11CCCC[C@@H]1N(CC1CC1)C(=O)c1ccc(Br)cc1 InChI=1S/C21H29BrN2O/c1-23-14-4-13-21(23)12-3-2-5-19(21)24(15-16-6-7-16)20(25)17-8-10-18(22)11-9-17/h8-11,16,19H,2-7,12-15H2,1H3/t19-,21+/m0/s1 CFDWVOCCPAMIBO-PZJWPPBQSA-N 50017072 4-Bromo-N-cyclopropylmethyl-N-(1-methyl-1-aza-spiro[4.5]dec-6-yl)-benzamide::CHEMBL22569 Mu-type opioid receptor Cavia cutleri 220 ChEMBL 10.1021/jm00126a019 10.7270/Q280536X 2542556 Fujimoto, RA; Boxer, J; Jackson, RH; Simke, JP; Neale, RF; Snowhill, EW; Barbaz, BJ; Williams, M; Sills, MA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017072&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14548236 103928400 CHEMBL22569 ZINC28254521 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032058 CN([C@H]1CCCC[C@@]11CCCN1C)C(=O)c1ccc(Cl)c(Cl)c1 InChI=1S/C18H24Cl2N2O/c1-21-11-5-10-18(21)9-4-3-6-16(18)22(2)17(23)13-7-8-14(19)15(20)12-13/h7-8,12,16H,3-6,9-11H2,1-2H3/t16-,18+/m0/s1 RNJHKFNXCUGTMS-FUHWJXTLSA-N 50017065 3,4-Dichloro-N-methyl-N-(1-methyl-1-aza-spiro[4.5]dec-6-yl)-benzamide::CHEMBL22211 Mu-type opioid receptor Cavia cutleri 6.3 ChEMBL 10.1021/jm00126a019 10.7270/Q280536X 2542556 Fujimoto, RA; Boxer, J; Jackson, RH; Simke, JP; Neale, RF; Snowhill, EW; Barbaz, BJ; Williams, M; Sills, MA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017065&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14548215 103928393 CHEMBL22211 ZINC28255458 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032061 CC(C)CN([C@H]1CCCC[C@@]11CCCN1C)C(=O)c1ccc(Br)cc1 InChI=1S/C21H31BrN2O/c1-16(2)15-24(20(25)17-8-10-18(22)11-9-17)19-7-4-5-12-21(19)13-6-14-23(21)3/h8-11,16,19H,4-7,12-15H2,1-3H3/t19-,21+/m0/s1 GJWJBSVJJDAPNU-PZJWPPBQSA-N 50017070 4-Bromo-N-isobutyl-N-(1-methyl-1-aza-spiro[4.5]dec-6-yl)-benzamide::CHEMBL22458 Mu-type opioid receptor Cavia cutleri 580 ChEMBL 10.1021/jm00126a019 10.7270/Q280536X 2542556 Fujimoto, RA; Boxer, J; Jackson, RH; Simke, JP; Neale, RF; Snowhill, EW; Barbaz, BJ; Williams, M; Sills, MA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017070 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017070&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14548238 103928398 CHEMBL22458 ZINC28256736 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032062 CN([C@H]1CCCC[C@@]11CCCN1C)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C19H26Cl2N2O/c1-22-11-5-10-19(22)9-4-3-6-17(19)23(2)18(24)13-14-7-8-15(20)16(21)12-14/h7-8,12,17H,3-6,9-11,13H2,1-2H3/t17-,19+/m0/s1 ZLVVIHOORPWHKA-PKOBYXMFSA-N 50017068 2-(3,4-Dichloro-phenyl)-N-methyl-N-(1-methyl-1-aza-spiro[4.5]dec-6-yl)-acetamide; hydrochloride::CHEMBL555852 Mu-type opioid receptor Cavia cutleri 87 ChEMBL 10.1021/jm00126a019 10.7270/Q280536X 2542556 Fujimoto, RA; Boxer, J; Jackson, RH; Simke, JP; Neale, RF; Snowhill, EW; Barbaz, BJ; Williams, M; Sills, MA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017068 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017068&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44458341 103928396 CHEMBL555852 ZINC28257197 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032067 CN1CCC[C@@]11CCCC[C@@H]1NC(=O)c1ccc(Br)cc1 InChI=1S/C17H23BrN2O/c1-20-12-4-11-17(20)10-3-2-5-15(17)19-16(21)13-6-8-14(18)9-7-13/h6-9,15H,2-5,10-12H2,1H3,(H,19,21)/t15-,17+/m0/s1 VZKMKYLRWSMHRB-DOTOQJQBSA-N 50017063 4-Bromo-N-(1-methyl-1-aza-spiro[4.5]dec-6-yl)-benzamide; hydrochloride::CHEMBL542069 Mu-type opioid receptor Cavia cutleri 600 ChEMBL 10.1021/jm00126a019 10.7270/Q280536X 2542556 Fujimoto, RA; Boxer, J; Jackson, RH; Simke, JP; Neale, RF; Snowhill, EW; Barbaz, BJ; Williams, M; Sills, MA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017063 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017063&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14548201 103928391 CHEMBL542069 ZINC28257794 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032068 CN1CCC[C@@]11CCCC[C@@H]1NC(=O)c1ccc(Cl)cc1 InChI=1S/C17H23ClN2O/c1-20-12-4-11-17(20)10-3-2-5-15(17)19-16(21)13-6-8-14(18)9-7-13/h6-9,15H,2-5,10-12H2,1H3,(H,19,21)/t15-,17+/m0/s1 PBDSARIWULTGBC-DOTOQJQBSA-N 50017079 4-Chloro-N-(1-methyl-1-aza-spiro[4.5]dec-6-yl)-benzamide; hydrochloride::CHEMBL539228 Mu-type opioid receptor Cavia cutleri 550 ChEMBL 10.1021/jm00126a019 10.7270/Q280536X 2542556 Fujimoto, RA; Boxer, J; Jackson, RH; Simke, JP; Neale, RF; Snowhill, EW; Barbaz, BJ; Williams, M; Sills, MA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017079&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14548203 103928407 CHEMBL539228 ZINC28257861 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032069 CN1CCC[C@@]11CCCC[C@@H]1NS(=O)(=O)c1ccc(Br)cc1 InChI=1S/C16H23BrN2O2S/c1-19-12-4-11-16(19)10-3-2-5-15(16)18-22(20,21)14-8-6-13(17)7-9-14/h6-9,15,18H,2-5,10-12H2,1H3/t15-,16+/m0/s1 TYMZWYRIAHJOSC-JKSUJKDBSA-N 50017069 4-Bromo-N-(1-methyl-1-aza-spiro[4.5]dec-6-yl)-benzenesulfonamide::CHEMBL22220 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm00126a019 10.7270/Q280536X 2542556 Fujimoto, RA; Boxer, J; Jackson, RH; Simke, JP; Neale, RF; Snowhill, EW; Barbaz, BJ; Williams, M; Sills, MA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017069 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017069&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44458295 103928397 CHEMBL22220 ZINC28252372 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032071 CN1CCC[C@@]11CCCC[C@@H]1NC(=O)c1ccc(Cl)c(Cl)c1 InChI=1S/C17H22Cl2N2O/c1-21-10-4-9-17(21)8-3-2-5-15(17)20-16(22)12-6-7-13(18)14(19)11-12/h6-7,11,15H,2-5,8-10H2,1H3,(H,20,22)/t15-,17+/m0/s1 CWQFCYGEJDNLMH-DOTOQJQBSA-N 50017077 3,4-Dichloro-N-(1-methyl-1-aza-spiro[4.5]dec-6-yl)-benzamide::CHEMBL282244 Mu-type opioid receptor Cavia cutleri 210 ChEMBL 10.1021/jm00126a019 10.7270/Q280536X 2542556 Fujimoto, RA; Boxer, J; Jackson, RH; Simke, JP; Neale, RF; Snowhill, EW; Barbaz, BJ; Williams, M; Sills, MA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017077&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14548209 103928405 CHEMBL282244 ZINC28257651 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032072 CN1CCC[C@@]11CCCC[C@@H]1NC(=O)c1ccccc1Br InChI=1S/C17H23BrN2O/c1-20-12-6-11-17(20)10-5-4-9-15(17)19-16(21)13-7-2-3-8-14(13)18/h2-3,7-8,15H,4-6,9-12H2,1H3,(H,19,21)/t15-,17+/m0/s1 RNMPAAHKRISTNC-DOTOQJQBSA-N 50017058 2-Bromo-N-(1-methyl-1-aza-spiro[4.5]dec-6-yl)-benzamide; hydrochloride::CHEMBL554212 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm00126a019 10.7270/Q280536X 2542556 Fujimoto, RA; Boxer, J; Jackson, RH; Simke, JP; Neale, RF; Snowhill, EW; Barbaz, BJ; Williams, M; Sills, MA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017058 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017058&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14548197 103928386 CHEMBL554212 ZINC28258160 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032078 CN([C@H]1CCCC[C@@]11CCCN1C)C(=O)c1ccc(Br)cc1 InChI=1S/C18H25BrN2O/c1-20-13-5-12-18(20)11-4-3-6-16(18)21(2)17(22)14-7-9-15(19)10-8-14/h7-10,16H,3-6,11-13H2,1-2H3/t16-,18+/m0/s1 WSLXSNJSFVVKJU-FUHWJXTLSA-N 50017071 4-Bromo-N-methyl-N-(1-methyl-1-aza-spiro[4.5]dec-6-yl)-benzamide; hydrochloride::CHEMBL553062 Mu-type opioid receptor Cavia cutleri 17 ChEMBL 10.1021/jm00126a019 10.7270/Q280536X 2542556 Fujimoto, RA; Boxer, J; Jackson, RH; Simke, JP; Neale, RF; Snowhill, EW; Barbaz, BJ; Williams, M; Sills, MA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017071&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14548213 103928399 CHEMBL553062 ZINC28257000 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032082 CN1CCC[C@@]11CCCC[C@@H]1NC(=O)c1cccc(Br)c1 InChI=1S/C17H23BrN2O/c1-20-11-5-10-17(20)9-3-2-8-15(17)19-16(21)13-6-4-7-14(18)12-13/h4,6-7,12,15H,2-3,5,8-11H2,1H3,(H,19,21)/t15-,17+/m0/s1 WCAACIAMWBEUCK-DOTOQJQBSA-N 50017062 3-Bromo-N-(1-methyl-1-aza-spiro[4.5]dec-6-yl)-benzamide; hydrochloride::CHEMBL544684 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm00126a019 10.7270/Q280536X 2542556 Fujimoto, RA; Boxer, J; Jackson, RH; Simke, JP; Neale, RF; Snowhill, EW; Barbaz, BJ; Williams, M; Sills, MA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017062 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017062&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14548199 103928390 CHEMBL544684 ZINC28256906 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032084 CN([C@H]1CCCC[C@@]11CCCN1C)C(=O)c1ccc(C)cc1 InChI=1S/C19H28N2O/c1-15-8-10-16(11-9-15)18(22)21(3)17-7-4-5-12-19(17)13-6-14-20(19)2/h8-11,17H,4-7,12-14H2,1-3H3/t17-,19+/m0/s1 SVDFQOGPLWODAK-PKOBYXMFSA-N 50017064 4,N-Dimethyl-N-(1-methyl-1-aza-spiro[4.5]dec-6-yl)-benzamide::CHEMBL23016 Mu-type opioid receptor Cavia cutleri 150 ChEMBL 10.1021/jm00126a019 10.7270/Q280536X 2542556 Fujimoto, RA; Boxer, J; Jackson, RH; Simke, JP; Neale, RF; Snowhill, EW; Barbaz, BJ; Williams, M; Sills, MA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017064&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14548217 103928392 CHEMBL23016 ZINC28255476 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032089 CN([C@H]1CCCC[C@@]11CCCN1C)C(=O)c1ccc(cc1)C(F)(F)F InChI=1S/C19H25F3N2O/c1-23-13-5-12-18(23)11-4-3-6-16(18)24(2)17(25)14-7-9-15(10-8-14)19(20,21)22/h7-10,16H,3-6,11-13H2,1-2H3/t16-,18+/m0/s1 HUFBLXFPRKMQOF-FUHWJXTLSA-N 50017060 CHEMBL553991::N-Methyl-N-(1-methyl-1-aza-spiro[4.5]dec-6-yl)-4-trifluoromethyl-benzamide; hydrochloride Mu-type opioid receptor Cavia cutleri 12 ChEMBL 10.1021/jm00126a019 10.7270/Q280536X 2542556 Fujimoto, RA; Boxer, J; Jackson, RH; Simke, JP; Neale, RF; Snowhill, EW; Barbaz, BJ; Williams, M; Sills, MA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017060 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017060&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14548219 103928388 CHEMBL553991 ZINC28255362 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032091 CN([C@H]1CCCC[C@@]11CCCN1C)C(=O)c1ccc(Br)cc1Cl InChI=1S/C18H24BrClN2O/c1-21-11-5-10-18(21)9-4-3-6-16(18)22(2)17(23)14-8-7-13(19)12-15(14)20/h7-8,12,16H,3-6,9-11H2,1-2H3/t16-,18+/m0/s1 PIVSRYNUXJQYNQ-FUHWJXTLSA-N 50017061 4-Bromo-2-chloro-N-methyl-N-(1-methyl-1-aza-spiro[4.5]dec-6-yl)-benzamide; hydrochloride::CHEMBL553782 Mu-type opioid receptor Cavia cutleri 16 ChEMBL 10.1021/jm00126a019 10.7270/Q280536X 2542556 Fujimoto, RA; Boxer, J; Jackson, RH; Simke, JP; Neale, RF; Snowhill, EW; Barbaz, BJ; Williams, M; Sills, MA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017061 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017061&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14548223 103928389 CHEMBL553782 ZINC28253748 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032093 CN1CCC[C@@]11CCCC[C@@H]1NC(=O)Cc1ccc(Br)cc1 InChI=1S/C18H25BrN2O/c1-21-12-4-11-18(21)10-3-2-5-16(18)20-17(22)13-14-6-8-15(19)9-7-14/h6-9,16H,2-5,10-13H2,1H3,(H,20,22)/t16-,18+/m0/s1 VKXIMAMXUANMDZ-FUHWJXTLSA-N 50017076 2-(4-Bromo-phenyl)-N-(1-methyl-1-aza-spiro[4.5]dec-6-yl)-acetamide; hydrochloride::CHEMBL555430 Mu-type opioid receptor Cavia cutleri 720 ChEMBL 10.1021/jm00126a019 10.7270/Q280536X 2542556 Fujimoto, RA; Boxer, J; Jackson, RH; Simke, JP; Neale, RF; Snowhill, EW; Barbaz, BJ; Williams, M; Sills, MA Ciba-Geigy Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017076&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14548229 103928404 CHEMBL555430 ZINC28252377 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033188 CN([C@H]1CCC2(CCCO2)C[C@@H]1N1CCCC1)C(=O)Cc1cccc2occc12 InChI=1S/C24H32N2O3/c1-25(23(27)16-18-6-4-7-22-19(18)9-15-28-22)20-8-11-24(10-5-14-29-24)17-21(20)26-12-2-3-13-26/h4,6-7,9,15,20-21H,2-3,5,8,10-14,16-17H2,1H3/t20-,21-,24?/m0/s1 JMBYBVLCYODBJQ-GAIPOIILSA-N 50008858 2-Benzofuran-4-yl-N-methyl-N-(7-pyrrolidin-1-yl-1-oxa-spiro[4.5]dec-8-yl)-acetamide; hydrochloride::CHEMBL539246 Mu-type opioid receptor Cavia cutleri 1260 ChEMBL 10.1021/jm00105a028 10.7270/Q2J103SG 1846919 Halfpenny, PR; Horwell, DC; Hughes, J; Humblet, C; Hunter, JC; Neuhaus, D; Rees, DC Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008858 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008858&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300802 103921959 CHEMBL539246 ZINC05965810 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033189 CN([C@H]1CCCC[C@@H]1N1CCCC1)C(=O)Cc1cccc2sccc12 InChI=1S/C21H28N2OS/c1-22(18-8-2-3-9-19(18)23-12-4-5-13-23)21(24)15-16-7-6-10-20-17(16)11-14-25-20/h6-7,10-11,14,18-19H,2-5,8-9,12-13,15H2,1H3/t18-,19-/m0/s1 SYHJZCCNQDFHJQ-OALUTQOASA-N 50008854 2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide; hydrochloride::CHEMBL543331 Mu-type opioid receptor Cavia cutleri 410 ChEMBL 10.1021/jm00105a028 10.7270/Q2J103SG 1846919 Halfpenny, PR; Horwell, DC; Hughes, J; Humblet, C; Hunter, JC; Neuhaus, D; Rees, DC Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008854&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9906722 103921955 CHEMBL543331 ZINC03779690 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033190 CC1C(C(=O)N(C)[C@H]2CCC3(CCCO3)C[C@@H]2N2CCCC2)c2cccc3cccc1c23 InChI=1S/C28H36N2O2/c1-19-21-10-5-8-20-9-6-11-22(26(20)21)25(19)27(31)29(2)23-12-14-28(13-7-17-32-28)18-24(23)30-15-3-4-16-30/h5-6,8-11,19,23-25H,3-4,7,12-18H2,1-2H3/t19?,23-,24-,25?,28?/m0/s1 XWROGPXUCYJQLL-VUPKEGFWSA-N 50008856 2-Methyl-acenaphthene-1-carboxylic acid methyl-(7-pyrrolidin-1-yl-1-oxa-spiro[4.5]dec-8-yl)-amide; hydrochloride::CHEMBL544276 Mu-type opioid receptor Cavia cutleri 244 ChEMBL 10.1021/jm00105a028 10.7270/Q2J103SG 1846919 Halfpenny, PR; Horwell, DC; Hughes, J; Humblet, C; Hunter, JC; Neuhaus, D; Rees, DC Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008856 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008856&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300800 103921957 CHEMBL544276 ZINC29569445 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033191 CC1C(C(=O)N(C)[C@H]2CCC3(CCCO3)C[C@@H]2N2CCNC2)c2cccc3cccc1c23 InChI=1S/C27H35N3O2/c1-18-20-8-3-6-19-7-4-9-21(25(19)20)24(18)26(31)29(2)22-10-12-27(11-5-15-32-27)16-23(22)30-14-13-28-17-30/h3-4,6-9,18,22-24,28H,5,10-17H2,1-2H3/t18?,22-,23-,24?,27?/m0/s1 FGPRCEIOCKKCMF-XCIMKVISSA-N 50008852 2-Methyl-acenaphthene-1-carboxylic acid (7-imidazolidin-1-yl-1-oxa-spiro[4.5]dec-8-yl)-methyl-amide; hydrochloride::CHEMBL543809 Mu-type opioid receptor Cavia cutleri 273 ChEMBL 10.1021/jm00105a028 10.7270/Q2J103SG 1846919 Halfpenny, PR; Horwell, DC; Hughes, J; Humblet, C; Hunter, JC; Neuhaus, D; Rees, DC Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008852&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300945 103921953 CHEMBL543809 ZINC29569279 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033193 CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C19H26Cl2N2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17-,18-/m1/s1 VQLPLYSROCPWFF-QZTJIDSGSA-N 50000296 CHEMBL441765::CHEMBL482811::U-50488H::US11492374, ID 1 Mu-type opioid receptor Cavia cutleri 880 ChEMBL 10.1021/jm00105a028 10.7270/Q2J103SG 1846919 Halfpenny, PR; Horwell, DC; Hughes, J; Humblet, C; Hunter, JC; Neuhaus, D; Rees, DC Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000296&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036289 103914903 73358 CHEMBL482811CHEMBL441765 1654 C11796 ZINC00643032 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033194 CC(C(=O)N(C)[C@H]1CCCC[C@@H]1N1CCCC1)c1cccc2sccc12 InChI=1S/C22H30N2OS/c1-16(17-8-7-11-21-18(17)12-15-26-21)22(25)23(2)19-9-3-4-10-20(19)24-13-5-6-14-24/h7-8,11-12,15-16,19-20H,3-6,9-10,13-14H2,1-2H3/t16?,19-,20-/m0/s1 UMIAZJFHSCKPMM-RFFXKOPCSA-N 50008851 2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-propionamide; hydrochloride::CHEMBL553114 Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm00105a028 10.7270/Q2J103SG 1846919 Halfpenny, PR; Horwell, DC; Hughes, J; Humblet, C; Hunter, JC; Neuhaus, D; Rees, DC Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008851&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300829 103921952 CHEMBL553114 ZINC13860895 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033195 CN([C@H]1CCC2(CCCO2)C[C@@H]1N1CCCC1)C(=O)Cc1cccc2ccccc12 InChI=1S/C26H34N2O2/c1-27(25(29)18-21-10-6-9-20-8-2-3-11-22(20)21)23-12-14-26(13-7-17-30-26)19-24(23)28-15-4-5-16-28/h2-3,6,8-11,23-24H,4-5,7,12-19H2,1H3/t23-,24-,26?/m0/s1 FOQROCUUQJEYDF-OKHNBNEASA-N 50008857 CHEMBL543329::N-Methyl-2-naphthalen-1-yl-N-(7-pyrrolidin-1-yl-1-oxa-spiro[4.5]dec-8-yl)-acetamide; hydrochloride Mu-type opioid receptor Cavia cutleri 864 ChEMBL 10.1021/jm00105a028 10.7270/Q2J103SG 1846919 Halfpenny, PR; Horwell, DC; Hughes, J; Humblet, C; Hunter, JC; Neuhaus, D; Rees, DC Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008857&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300804 103921958 CHEMBL543329 ZINC29569564 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033198 CN([C@H]1CCC2(CCCO2)C[C@@H]1N1CCCC1)C(=O)C1CCc2c(Br)sc3cccc1c23 InChI=1S/C26H33BrN2O2S/c1-28(20-10-12-26(11-5-15-31-26)16-21(20)29-13-2-3-14-29)25(30)18-8-9-19-23-17(18)6-4-7-22(23)32-24(19)27/h4,6-7,18,20-21H,2-3,5,8-16H2,1H3/t18?,20-,21-,26?/m0/s1 WPDLVWOUMWRXIF-UGWRYHMVSA-N 50008853 2-Bromo-4,5-dihydro-3H-naphtho[1,8-bc]thiophene-5-carboxylic acid methyl-(7-pyrrolidin-1-yl-1-oxa-spiro[4.5]dec-8-yl)-amide; compound with toluene-4-sulfonic acid::CHEMBL300832 Mu-type opioid receptor Cavia cutleri 170 ChEMBL 10.1021/jm00105a028 10.7270/Q2J103SG 1846919 Halfpenny, PR; Horwell, DC; Hughes, J; Humblet, C; Hunter, JC; Neuhaus, D; Rees, DC Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008853&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300701 103921954 CHEMBL300832 ZINC29553895 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50033200 CN([C@H]1CCC2(CCCO2)C[C@@H]1N1CCCC1)C(=O)C1CCc2csc3cccc1c23 InChI=1S/C26H34N2O2S/c1-27(25(29)20-9-8-18-17-31-23-7-4-6-19(20)24(18)23)21-10-12-26(11-5-15-30-26)16-22(21)28-13-2-3-14-28/h4,6-7,17,20-22H,2-3,5,8-16H2,1H3/t20?,21-,22-,26?/m0/s1 MPLOOKCTVWUMQO-UBFBPUDLSA-N 50008855 4,5-Dihydro-3H-naphtho[1,8-bc]thiophene-5-carboxylic acid methyl-(7-pyrrolidin-1-yl-1-oxa-spiro[4.5]dec-8-yl)-amide; compound with toluene-4-sulfonic acid::CHEMBL300831 Mu-type opioid receptor Cavia cutleri 62.0 ChEMBL 10.1021/jm00105a028 10.7270/Q2J103SG 1846919 Halfpenny, PR; Horwell, DC; Hughes, J; Humblet, C; Hunter, JC; Neuhaus, D; Rees, DC Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008855&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300699 103921956 CHEMBL300831 ZINC29553888 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50034397 CN([C@H]1C[C@]2(CC(=C)C(=O)O2)CC[C@@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C23H28Cl2N2O3/c1-15-13-23(30-22(15)29)8-7-19(27-9-3-4-10-27)20(14-23)26(2)21(28)12-16-5-6-17(24)18(25)11-16/h5-6,11,19-20H,1,3-4,7-10,12-14H2,2H3/t19-,20-,23+/m0/s1 AIGXNGMYDUNNBN-SXWKCWPCSA-N 50000781 2-(3,4-Dichloro-phenyl)-N-methyl-N-(3-methylene-2-oxo-8-pyrrolidin-1-yl-1-oxa-spiro[4.5]dec-7-yl)-acetamide::CHEMBL70311 Mu-type opioid receptor Cavia cutleri 2610 ChEMBL 10.1021/jm00090a015 10.7270/Q20K296N 1319495 Cheng, CY; Wu, SC; Hsin, LW; Tam, SW National Taiwan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000781 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000781&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15177774 103915323 CHEMBL70311 ZINC13456655 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50035511 CC[C@@H]1NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SSC(C)(C)[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)O InChI=1S/C32H45N5O7S2/c1-6-22-27(40)35-23(17-18-10-8-7-9-11-18)28(41)37-25(30(43)44)32(4,5)46-45-31(2,3)24(29(42)34-22)36-26(39)21(33)16-19-12-14-20(38)15-13-19/h7-15,21-25,30,38,43-44H,6,16-17,33H2,1-5H3,(H,34,42)(H,35,40)(H,36,39)(H,37,41)/t21-,22-,23-,24+,25+/m0/s1 IEVGUHJUACDFNA-AMGAHSPLSA-N 50453339 CHEMBL2372412 Mu-type opioid receptor Cavia cutleri 4900 ChEMBL 10.1021/jm00037a007 10.7270/Q2DR2W47 8201592 Haaseth, RC; Horan, PJ; Bilsky, EJ; Davis, P; Zalewska, T; Slaninova, J; Yamamura, HI; Weber, SJ; Davis, TP; Porreca, F University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453339 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453339&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73348692 225145906 CHEMBL2372412 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50035518 C[C@@H]1NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SSC(C)(C)[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)O InChI=1S/C31H43N5O7S2/c1-17-25(38)34-22(16-18-9-7-6-8-10-18)27(40)36-24(29(42)43)31(4,5)45-44-30(2,3)23(28(41)33-17)35-26(39)21(32)15-19-11-13-20(37)14-12-19/h6-14,17,21-24,29,37,42-43H,15-16,32H2,1-5H3,(H,33,41)(H,34,38)(H,35,39)(H,36,40) RUNRDTYBZFTQFP-UHFFFAOYSA-N 50041669 2-Amino-N-(7-benzyl-4-dihydroxymethyl-3,3,10,14,14-pentamethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradec-13-yl)-3-(4-hydroxy-phenyl)-propionamide::CHEMBL43637 Mu-type opioid receptor Cavia cutleri 54000 ChEMBL 10.1021/jm00037a007 10.7270/Q2DR2W47 8201592 Haaseth, RC; Horan, PJ; Bilsky, EJ; Davis, P; Zalewska, T; Slaninova, J; Yamamura, HI; Weber, SJ; Davis, TP; Porreca, F University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041669 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041669&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73356295 103973359 CHEMBL43637 ZINC49772316 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50035519 CC[C@H]1NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SSC(C)(C)[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)O InChI=1S/C32H45N5O7S2/c1-6-22-27(40)35-23(17-18-10-8-7-9-11-18)28(41)37-25(30(43)44)32(4,5)46-45-31(2,3)24(29(42)34-22)36-26(39)21(33)16-19-12-14-20(38)15-13-19/h7-15,21-25,30,38,43-44H,6,16-17,33H2,1-5H3,(H,34,42)(H,35,40)(H,36,39)(H,37,41)/t21-,22+,23-,24+,25+/m0/s1 IEVGUHJUACDFNA-HNRDJRCMSA-N 50041668 2-Amino-N-((S)-7-benzyl-4-dihydroxymethyl-10-ethyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradec-13-yl)-3-(4-hydroxy-phenyl)-propionamide::CHEMBL2372411 Mu-type opioid receptor Cavia cutleri 30000 ChEMBL 10.1021/jm00037a007 10.7270/Q2DR2W47 8201592 Haaseth, RC; Horan, PJ; Bilsky, EJ; Davis, P; Zalewska, T; Slaninova, J; Yamamura, HI; Weber, SJ; Davis, TP; Porreca, F University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041668 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041668&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73345681 103973358 CHEMBL2372411 ZINC49695249 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50035520 C[C@H]1NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SSC(C)(C)[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)O InChI=1S/C31H43N5O7S2/c1-17-25(38)34-22(16-18-9-7-6-8-10-18)27(40)36-24(29(42)43)31(4,5)45-44-30(2,3)23(28(41)33-17)35-26(39)21(32)15-19-11-13-20(37)14-12-19/h6-14,17,21-24,29,37,42-43H,15-16,32H2,1-5H3,(H,33,41)(H,34,38)(H,35,39)(H,36,40)/t17-,21+,22+,23-,24-/m1/s1 RUNRDTYBZFTQFP-JQSHXNIYSA-N 50041665 2-Amino-N-(7-benzyl-4-dihydroxymethyl-10-ethyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradec-13-yl)-3-(4-hydroxy-phenyl)-propionamide::CHEMBL2372423 Mu-type opioid receptor Cavia cutleri 33000 ChEMBL 10.1021/jm00037a007 10.7270/Q2DR2W47 8201592 Haaseth, RC; Horan, PJ; Bilsky, EJ; Davis, P; Zalewska, T; Slaninova, J; Yamamura, HI; Weber, SJ; Davis, TP; Porreca, F University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041665 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041665&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73345682 103973355 CHEMBL2372423 ZINC49627267 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50035521 CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23-,24-/m0/s1 MCMMCRYPQBNCPH-DVKRWUGUSA-N 50001683 13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid::7-Benzyl-10-{[3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL294616::DPDPE Mu-type opioid receptor Cavia cutleri 7300 ChEMBL 10.1021/jm00037a007 10.7270/Q2DR2W47 8201592 Haaseth, RC; Horan, PJ; Bilsky, EJ; Davis, P; Zalewska, T; Slaninova, J; Yamamura, HI; Weber, SJ; Davis, TP; Porreca, F University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001683&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299404 103916113 CHEMBL294616 ZINC27520031 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50035522 CC1(C)SSC(C)(C)[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(O)O InChI=1S/C31H43N5O8S2/c1-30(2)23(35-25(39)20(32)14-18-10-12-19(38)13-11-18)28(42)34-22(16-37)27(41)33-21(15-17-8-6-5-7-9-17)26(40)36-24(29(43)44)31(3,4)46-45-30/h5-13,20-24,29,37-38,43-44H,14-16,32H2,1-4H3,(H,33,41)(H,34,42)(H,35,39)(H,36,40)/t20-,21-,22-,23+,24+/m0/s1 KWGMXBJZDBBUHD-ZROJVYTPSA-N 50041663 2-Amino-N-(7-benzyl-4-dihydroxymethyl-10-hydroxymethyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradec-13-yl)-3-(4-hydroxy-phenyl)-propionamide::CHEMBL2372409 Mu-type opioid receptor Cavia cutleri 39000 ChEMBL 10.1021/jm00037a007 10.7270/Q2DR2W47 8201592 Haaseth, RC; Horan, PJ; Bilsky, EJ; Davis, P; Zalewska, T; Slaninova, J; Yamamura, HI; Weber, SJ; Davis, TP; Porreca, F University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041663 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041663&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73348691 103973353 CHEMBL2372409 ZINC49627486 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50034400 CN([C@H]1C[C@@]2(CC(=C)C(=O)O2)CC[C@@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C23H28Cl2N2O3/c1-15-13-23(30-22(15)29)8-7-19(27-9-3-4-10-27)20(14-23)26(2)21(28)12-16-5-6-17(24)18(25)11-16/h5-6,11,19-20H,1,3-4,7-10,12-14H2,2H3/t19-,20-,23-/m0/s1 AIGXNGMYDUNNBN-JTAQYXEDSA-N 50000786 2-(3,4-Dichloro-phenyl)-N-methyl-N-(3-methylene-2-oxo-8-pyrrolidin-1-yl-1-oxa-spiro[4.5]dec-7-yl)-acetamide(SMBU-1)::CHEMBL307235 Mu-type opioid receptor Cavia cutleri 3150 ChEMBL 10.1021/jm00090a015 10.7270/Q20K296N 1319495 Cheng, CY; Wu, SC; Hsin, LW; Tam, SW National Taiwan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000786&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15177773 103915328 CHEMBL307235 ZINC13456652 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50034404 CN([C@H]1CCC2(C[C@@H]1N1CCCC1)OCCO2)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C21H28Cl2N2O3/c1-24(20(26)13-15-4-5-16(22)17(23)12-15)18-6-7-21(27-10-11-28-21)14-19(18)25-8-2-3-9-25/h4-5,12,18-19H,2-3,6-11,13-14H2,1H3/t18-,19-/m0/s1 NFIYELFTWUFXOM-OALUTQOASA-N 50000784 2-(3,4-Dichloro-phenyl)-N-methyl-N-(7-pyrrolidin-1-yl-1,4-dioxa-spiro[4.5]dec-8-yl)-acetamide::CHEMBL73226 Mu-type opioid receptor Cavia cutleri 702 ChEMBL 10.1021/jm00090a015 10.7270/Q20K296N 1319495 Cheng, CY; Wu, SC; Hsin, LW; Tam, SW National Taiwan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000784&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 13062443 103915326 CHEMBL73226 ZINC13456661 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50034405 CN([C@H]1CC[C@@]2(CCCO2)C[C@@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C22H30Cl2N2O2/c1-25(21(27)14-16-5-6-17(23)18(24)13-16)19-7-9-22(8-4-12-28-22)15-20(19)26-10-2-3-11-26/h5-6,13,19-20H,2-4,7-12,14-15H2,1H3/t19-,20-,22-/m0/s1 NYKCGQQJNVPOLU-ONTIZHBOSA-N 83436 2-(3,4-dichlorophenyl)-N-methyl-N-[(5R,7S,8S)-7-(1-pyrrolidinyl)-1-oxaspiro[4.5]decan-8-yl]acetamide;methanesulfonic acid::2-(3,4-dichlorophenyl)-N-methyl-N-[(5R,7S,8S)-7-pyrrolidin-1-yl-1-oxaspiro[4.5]decan-8-yl]acetamide;methanesulfonic acid::2-(3,4-dichlorophenyl)-N-methyl-N-[(5R,7S,8S)-7-pyrrolidin-1-yl-1-oxaspiro[4.5]decan-8-yl]ethanamide;methanesulfonic acid::2-(3,4-dichlorophenyl)-N-methyl-N-[(5R,7S,8S)-7-pyrrolidino-1-oxaspiro[4.5]decan-8-yl]acetamide;mesylic acid::MLS002153429::SMR000326825::Spiradoline::U-62066::cid_55651 Mu-type opioid receptor Cavia cutleri 252 ChEMBL 10.1021/jm00090a015 10.7270/Q20K296N 1319495 Cheng, CY; Wu, SC; Hsin, LW; Tam, SW National Taiwan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=83436 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=83436&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 55652 252658631 ZINC32963898 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50034406 CN([C@H]1CC(=O)CC[C@@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C19H24Cl2N2O2/c1-22(19(25)11-13-4-6-15(20)16(21)10-13)18-12-14(24)5-7-17(18)23-8-2-3-9-23/h4,6,10,17-18H,2-3,5,7-9,11-12H2,1H3/t17-,18-/m0/s1 PXDHKHOBECBLPH-ROUUACIJSA-N 50000785 2-(3,4-Dichloro-phenyl)-N-methyl-N-(5-oxo-2-pyrrolidin-1-yl-cyclohexyl)-acetamide::CHEMBL74010 Mu-type opioid receptor Cavia cutleri 13000 ChEMBL 10.1021/jm00090a015 10.7270/Q20K296N 1319495 Cheng, CY; Wu, SC; Hsin, LW; Tam, SW National Taiwan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000785&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15177772 103915327 CHEMBL74010 ZINC13456665 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50034408 CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C19H26Cl2N2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17-,18-/m1/s1 VQLPLYSROCPWFF-QZTJIDSGSA-N 50000296 CHEMBL441765::CHEMBL482811::U-50488H::US11492374, ID 1 Mu-type opioid receptor Cavia cutleri 825 ChEMBL 10.1021/jm00090a015 10.7270/Q20K296N 1319495 Cheng, CY; Wu, SC; Hsin, LW; Tam, SW National Taiwan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000296&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036289 103914903 73358 CHEMBL482811CHEMBL441765 1654 C11796 ZINC00643032 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50034410 CN([C@H]1CC2(CC[C@@H]1N1CCCC1)OCCO2)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C21H28Cl2N2O3/c1-24(20(26)13-15-4-5-16(22)17(23)12-15)19-14-21(27-10-11-28-21)7-6-18(19)25-8-2-3-9-25/h4-5,12,18-19H,2-3,6-11,13-14H2,1H3/t18-,19-/m0/s1 XAQOJSHIURWQDN-OALUTQOASA-N 50000782 2-(3,4-Dichloro-phenyl)-N-methyl-N-(8-pyrrolidin-1-yl-1,4-dioxa-spiro[4.5]dec-7-yl)-acetamide::CHEMBL73131 Mu-type opioid receptor Cavia cutleri 5210 ChEMBL 10.1021/jm00090a015 10.7270/Q20K296N 1319495 Cheng, CY; Wu, SC; Hsin, LW; Tam, SW National Taiwan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000782&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 13062446 103915324 CHEMBL73131 ZINC13456658 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50034499 O[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45 InChI=1S/C20H25NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,14-15,18,22-24H,1-2,5-10H2/t14-,15-,18+,19+,20-/m1/s1 JLVNEHKORQFVQJ-PYIJOLGTSA-N 50001709 4-cyclopropylmethyl-(13R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-triene-10,14,17-triol::CHEMBL140278::CHEMBL558140::Naltrexone-6-beta-ol Mu-type opioid receptor Cavia cutleri 2.2 ChEMBL 10.1021/jm00091a005 10.7270/Q2GH9JKS 1320121 Dasher, WE; Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001709 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001709&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5486554 103916124 CHEMBL140278CHEMBL558140 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50034500 Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1 UZHSEJADLWPNLE-GRGSLBFTSA-N 50000788 (morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(naloxone) 4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::(naloxone)4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::(naloxone)4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one (naloxone)::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one( Naloxone)::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(Naxolone)::4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(naloxone)C2H2O4::Analog of 14-(Arylhydroxyamino)codeinone::NALOXONE::NARCAN::SUBOXONE::[17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydroxymorphinan-6-one Mu-type opioid receptor Cavia cutleri 8.9 ChEMBL 10.1021/jm00091a005 10.7270/Q2GH9JKS 1320121 Dasher, WE; Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000788&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5284596 103915330 7459 DB01183 1676 C07252 ZINC00389747 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50034503 CCC12CCN(CC3(O)CC3)C(Cc3ccc(O)cc13)C2(C)C InChI=1S/C20H29NO2/c1-4-20-9-10-21(13-19(23)7-8-19)17(18(20,2)3)11-14-5-6-15(22)12-16(14)20/h5-6,12,17,22-23H,4,7-11,13H2,1-3H3 ZDXGFIXMPOUDFF-UHFFFAOYSA-N 50013388 6-Ethyl-3-(1-hydroxy-cyclopropylmethyl)-11,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::BREMAZOCINE(-)::Bremazocine::CHEMBL350384 Mu-type opioid receptor Cavia cutleri 1.8 ChEMBL 10.1021/jm00091a005 10.7270/Q2GH9JKS 1320121 Dasher, WE; Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013388 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013388&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 1223 103925603 CHEMBL350384 ZINC03870315 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50034506 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1 DQCKKXVULJGBQN-XFWGSAIBSA-N 60212 (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::MLS000069607::NALTREXONE HYDROCHLORIDE::SMR000058767::US10988481, Compound NTX::US9107954, naltrexone::cid_5485201 Mu-type opioid receptor Cavia cutleri 0.730000 ChEMBL 10.1021/jm00091a005 10.7270/Q2GH9JKS 1320121 Dasher, WE; Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60212&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5360515 252639834 DB00704 C07253 ZINC00001773 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50034510 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)OCCN=S InChI=1S/C22H28N2O4S/c25-15-4-3-14-11-17-22(26)6-5-16(27-10-8-23-29)20-21(22,18(14)19(15)28-20)7-9-24(17)12-13-1-2-13/h3-4,13,16-17,20,25-26H,1-2,5-12H2/t16-,17-,20+,21+,22-/m1/s1 JWJRPPUYZVLUJO-KXIGMZGYSA-N 50453225 CHEMBL2310843 Mu-type opioid receptor Cavia cutleri 2.3 ChEMBL 10.1021/jm00091a005 10.7270/Q2GH9JKS 1320121 Dasher, WE; Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453225 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453225&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71719111 225145896 CHEMBL2310843 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50034513 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)OC[C@@H]1CO1 InChI=1S/C23H29NO5/c25-16-4-3-14-9-18-23(26)6-5-17(28-12-15-11-27-15)21-22(23,19(14)20(16)29-21)7-8-24(18)10-13-1-2-13/h3-4,13,15,17-18,21,25-26H,1-2,5-12H2/t15-,17+,18+,21-,22-,23+/m0/s1 MRMVSXBCKQGIRC-HHWLIEDYSA-N 50000797 4-cyclopropylmethyl-14-(2-oxiranylmethoxy)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-triene-10,17-diol::CHEMBL80434 Mu-type opioid receptor Cavia cutleri 3.5 ChEMBL 10.1021/jm00091a005 10.7270/Q2GH9JKS 1320121 Dasher, WE; Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000797&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15663406 103915339 CHEMBL80434 ZINC13724963 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50034518 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)OC[C@@H]1CC(=C)C(=O)O1 InChI=1S/C26H31NO6/c1-14-10-17(32-24(14)29)13-31-19-6-7-26(30)20-11-16-4-5-18(28)22-21(16)25(26,23(19)33-22)8-9-27(20)12-15-2-3-15/h4-5,15,17,19-20,23,28,30H,1-3,6-13H2/t17-,19+,20+,23-,25-,26+/m0/s1 AYJLAUNORPKULA-NOJKVUSZSA-N 50000789 5-[4-cyclopropylmethyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-yloxymethyl]-3-methylenetetrahydro-2-furanone::CHEMBL80531 Mu-type opioid receptor Cavia cutleri 3.4 ChEMBL 10.1021/jm00091a005 10.7270/Q2GH9JKS 1320121 Dasher, WE; Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000789 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000789&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15663420 103915331 CHEMBL80531 ZINC13724975 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50034522 CC(=O)O[C@]12CC[C@@H](OC[C@H]3CC(=C)C(=O)O3)[C@@H]3Oc4c5c(C[C@H]1N(CC1CC1)CC[C@@]235)ccc4O InChI=1S/C28H33NO7/c1-15-11-19(34-26(15)32)14-33-21-7-8-28(36-16(2)30)22-12-18-5-6-20(31)24-23(18)27(28,25(21)35-24)9-10-29(22)13-17-3-4-17/h5-6,17,19,21-22,25,31H,1,3-4,7-14H2,2H3/t19-,21-,22-,25+,27+,28-/m1/s1 YGMJUEYNRVHCAT-WZWNCYKESA-N 50000798 4-cyclopropylmethyl-10-hydroxy-14-(4-methylene-5-oxotetrahydro-2-furanylmethoxy)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-17-yl acetate::CHEMBL78932 Mu-type opioid receptor Cavia cutleri 2.2 ChEMBL 10.1021/jm00091a005 10.7270/Q2GH9JKS 1320121 Dasher, WE; Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000798&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15663417 103915340 CHEMBL78932 ZINC13724971 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50034523 CC(=O)O[C@]12CC[C@@H](OC[C@@H]3CC(=C)C(=O)O3)[C@@H]3Oc4c5c(C[C@H]1N(CC1CC1)CC[C@@]235)ccc4O InChI=1S/C28H33NO7/c1-15-11-19(34-26(15)32)14-33-21-7-8-28(36-16(2)30)22-12-18-5-6-20(31)24-23(18)27(28,25(21)35-24)9-10-29(22)13-17-3-4-17/h5-6,17,19,21-22,25,31H,1,3-4,7-14H2,2H3/t19-,21+,22+,25-,27-,28+/m0/s1 YGMJUEYNRVHCAT-OOXKPLBXSA-N 50000796 4-cyclopropylmethyl-10-hydroxy-14-(4-methylene-5-oxotetrahydro-2-furanylmethoxy)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-17-yl acetate::CHEMBL310785 Mu-type opioid receptor Cavia cutleri 2.8 ChEMBL 10.1021/jm00091a005 10.7270/Q2GH9JKS 1320121 Dasher, WE; Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000796&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15663418 103915338 CHEMBL310785 ZINC13724979 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50034524 COC(=O)C(=C)CO[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45 InChI=1S/C25H31NO6/c1-14(23(28)30-2)13-31-18-7-8-25(29)19-11-16-5-6-17(27)21-20(16)24(25,22(18)32-21)9-10-26(19)12-15-3-4-15/h5-6,15,18-19,22,27,29H,1,3-4,7-13H2,2H3/t18-,19-,22+,24+,25-/m1/s1 ZLKXBHFJETUNMU-WXIYZNRCSA-N 50000790 CHEMBL76023::methyl 2-[4-cyclopropylmethyl-10,17-dihydroxy-(13R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-trien-14-yloxymethyl]acrylate::methyl 2-[4-cyclopropylmethyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-yloxymethyl]acrylate Mu-type opioid receptor Cavia cutleri 2.5 ChEMBL 10.1021/jm00091a005 10.7270/Q2GH9JKS 1320121 Dasher, WE; Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000790&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10026312 103915332 CHEMBL76023 ZINC13724983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50034527 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)OC[C@H]1CC(=C)C(=O)O1 InChI=1S/C26H31NO6/c1-14-10-17(32-24(14)29)13-31-19-6-7-26(30)20-11-16-4-5-18(28)22-21(16)25(26,23(19)33-22)8-9-27(20)12-15-2-3-15/h4-5,15,17,19-20,23,28,30H,1-3,6-13H2/t17-,19-,20-,23+,25+,26-/m1/s1 AYJLAUNORPKULA-NMPOJTJSSA-N 50000795 5-[4-cyclopropylmethyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-yloxymethyl]-3-methylenetetrahydro-2-furanone::CHEMBL78796 Mu-type opioid receptor Cavia cutleri 4.2 ChEMBL 10.1021/jm00091a005 10.7270/Q2GH9JKS 1320121 Dasher, WE; Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000795 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000795&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15663419 103915337 CHEMBL78796 ZINC13724967 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50034532 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)OC[C@H]1CO1 InChI=1S/C23H29NO5/c25-16-4-3-14-9-18-23(26)6-5-17(28-12-15-11-27-15)21-22(23,19(14)20(16)29-21)7-8-24(18)10-13-1-2-13/h3-4,13,15,17-18,21,25-26H,1-2,5-12H2/t15-,17-,18-,21+,22+,23-/m1/s1 MRMVSXBCKQGIRC-LDYNJOKQSA-N 50000793 4-cyclopropylmethyl-14-(2-oxiranylmethoxy)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-triene-10,17-diol::CHEMBL311912 Mu-type opioid receptor Cavia cutleri 2.9 ChEMBL 10.1021/jm00091a005 10.7270/Q2GH9JKS 1320121 Dasher, WE; Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000793&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15663405 103915335 CHEMBL311912 ZINC13724959 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50034544 Oc1ccc2CC3N(CCc4ccccc4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2ccccc2c1C[C@@]35O InChI=1S/C30H28N2O3/c33-23-11-10-19-16-24-30(34)17-21-20-8-4-5-9-22(20)31-26(21)28-29(30,25(19)27(23)35-28)13-15-32(24)14-12-18-6-2-1-3-7-18/h1-11,24,28,31,33-34H,12-17H2/t24?,28-,29-,30+/m0/s1 FZLPZVPOKOYQGI-JYBLDVITSA-N 50001679 22-phenethyl-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm00101a009 10.7270/Q2DF6RTZ 1333013 Portoghese, PS; Larson, DL; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001679 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001679&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44357457 103916109 ZINC13729840 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037271 CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](CSCCSC(C)(C)[C@@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCN=C(N)N)NC1=O)C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C61H97N21O12S2/c1-5-34(2)47-56(93)78-41(17-11-25-72-60(68)69)57(94)82-26-12-18-44(82)55(92)81-48(49(63)86)61(3,4)96-28-27-95-33-43(54(91)77-39(15-9-23-70-58(64)65)51(88)76-40(52(89)80-47)16-10-24-71-59(66)67)79-53(90)42(30-35-13-7-6-8-14-35)75-46(85)32-73-45(84)31-74-50(87)38(62)29-36-19-21-37(83)22-20-36/h6-8,13-14,19-22,34,38-44,47-48,83H,5,9-12,15-18,23-33,62H2,1-4H3,(H2,63,86)(H,73,84)(H,74,87)(H,75,85)(H,76,88)(H,77,91)(H,78,93)(H,79,90)(H,80,89)(H,81,92)(H4,64,65,70)(H4,66,67,71)(H4,68,69,72)/t34-,38-,39-,40-,41-,42-,43+,44-,47-,48-/m0/s1 WJOUPUVSUGSQGN-JJULPNQFSA-N 50038015 CHEMBL2370631::Tyr-Gly-Gly-Phe-Pen-Arg-Arg-Ile-Arg-Pro-Pen-NH2 Mu-type opioid receptor Cavia cutleri 99 ChEMBL 10.1021/jm00049a010 10.7270/Q22N51BK 7966152 Meyer, JP; Collins, N; Lung, FD; Davis, P; Zalewska, T; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038015&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73345484 103945464 CHEMBL2370631 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037272 CC[C@H](C)[C@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SCCSC(C)(C)[C@H](NC(=O)[C@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC1=O)C(N)=O InChI=1S/C63H101N21O12S2/c1-7-35(2)47-56(94)80-42(19-13-27-74-61(70)71)58(96)84-28-14-20-44(84)55(93)82-48(50(65)88)62(3,4)97-29-30-98-63(5,6)49(57(95)79-40(17-11-25-72-59(66)67)52(90)78-41(53(91)81-47)18-12-26-73-60(68)69)83-54(92)43(32-36-15-9-8-10-16-36)77-46(87)34-75-45(86)33-76-51(89)39(64)31-37-21-23-38(85)24-22-37/h8-10,15-16,21-24,35,39-44,47-49,85H,7,11-14,17-20,25-34,64H2,1-6H3,(H2,65,88)(H,75,86)(H,76,89)(H,77,87)(H,78,90)(H,79,95)(H,80,94)(H,81,91)(H,82,93)(H,83,92)(H4,66,67,72)(H4,68,69,73)(H4,70,71,74)/t35-,39-,40+,41-,42-,43-,44+,47+,48+,49+/m0/s1 WATVUOQHRHGCSA-AAGWLRKLSA-N 50038017 CHEMBL263509::Tyr-Gly-Gly-Phe-D-Pen-Arg-Arg-Ile-Arg-Pro-D-Pen-NH2 Mu-type opioid receptor Cavia cutleri 563 ChEMBL 10.1021/jm00049a010 10.7270/Q22N51BK 7966152 Meyer, JP; Collins, N; Lung, FD; Davis, P; Zalewska, T; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038017&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44350794 103945466 CHEMBL263509 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037274 CC[C@H](C)[C@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@H](CSCCSC(C)(C)[C@H](NC(=O)[C@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC1=O)C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C61H97N21O12S2/c1-5-34(2)47-56(93)78-41(17-11-25-72-60(68)69)57(94)82-26-12-18-44(82)55(92)81-48(49(63)86)61(3,4)96-28-27-95-33-43(54(91)77-39(15-9-23-70-58(64)65)51(88)76-40(52(89)80-47)16-10-24-71-59(66)67)79-53(90)42(30-35-13-7-6-8-14-35)75-46(85)32-73-45(84)31-74-50(87)38(62)29-36-19-21-37(83)22-20-36/h6-8,13-14,19-22,34,38-44,47-48,83H,5,9-12,15-18,23-33,62H2,1-4H3,(H2,63,86)(H,73,84)(H,74,87)(H,75,85)(H,76,88)(H,77,91)(H,78,93)(H,79,90)(H,80,89)(H,81,92)(H4,64,65,70)(H4,66,67,71)(H4,68,69,72)/t34-,38-,39+,40-,41-,42-,43-,44+,47+,48+/m0/s1 WJOUPUVSUGSQGN-DHILHQQKSA-N 50038021 CHEMBL414713::Tyr-Gly-Gly-Phe-D-Cys-Arg-Arg-Ile-Arg-Pro-D-Pen-NH2 Mu-type opioid receptor Cavia cutleri 108 ChEMBL 10.1021/jm00049a010 10.7270/Q22N51BK 7966152 Meyer, JP; Collins, N; Lung, FD; Davis, P; Zalewska, T; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038021&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44350667 103945470 CHEMBL414713 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037280 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C63H104N22O12/c1-5-37(4)51(59(96)82-45(20-13-29-75-63(71)72)60(97)85-30-14-21-48(85)58(95)79-42(52(66)89)17-9-10-26-64)84-55(92)44(19-12-28-74-62(69)70)80-54(91)43(18-11-27-73-61(67)68)81-56(93)46(31-36(2)3)83-57(94)47(33-38-15-7-6-8-16-38)78-50(88)35-76-49(87)34-77-53(90)41(65)32-39-22-24-40(86)25-23-39/h6-8,15-16,22-25,36-37,41-48,51,86H,5,9-14,17-21,26-35,64-65H2,1-4H3,(H2,66,89)(H,76,87)(H,77,90)(H,78,88)(H,79,95)(H,80,91)(H,81,93)(H,82,96)(H,83,94)(H,84,92)(H4,67,68,73)(H4,69,70,74)(H4,71,72,75)/t37-,41-,42-,43-,44-,45-,46+,47-,48-,51-/m0/s1 OKJAOUBQLSWUNX-HBHMOHGPSA-N 50038013 CHEMBL374268::Tyr-Gly-Gly-Phe-Cys-Arg-Arg-Ile-Arg-Pro-Cys-NH2 Mu-type opioid receptor Cavia cutleri 116 ChEMBL 10.1021/jm00049a010 10.7270/Q22N51BK 7966152 Meyer, JP; Collins, N; Lung, FD; Davis, P; Zalewska, T; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038013&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11818885 103945462 CHEMBL374268 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037285 CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SCCSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCN=C(N)N)NC1=O)C(N)=O InChI=1S/C61H97N21O12S2/c1-5-34(2)47-55(92)78-41(17-11-25-72-60(68)69)57(94)82-26-12-18-44(82)54(91)79-43(49(63)86)33-95-27-28-96-61(3,4)48(56(93)77-39(15-9-23-70-58(64)65)51(88)76-40(52(89)80-47)16-10-24-71-59(66)67)81-53(90)42(30-35-13-7-6-8-14-35)75-46(85)32-73-45(84)31-74-50(87)38(62)29-36-19-21-37(83)22-20-36/h6-8,13-14,19-22,34,38-44,47-48,83H,5,9-12,15-18,23-33,62H2,1-4H3,(H2,63,86)(H,73,84)(H,74,87)(H,75,85)(H,76,88)(H,77,93)(H,78,92)(H,79,91)(H,80,89)(H,81,90)(H4,64,65,70)(H4,66,67,71)(H4,68,69,72)/t34-,38-,39-,40-,41-,42-,43-,44-,47-,48-/m0/s1 YQNZELNRCAEXEY-XNCNPLRTSA-N 50038012 CHEMBL2370629::Tyr-Gly-Gly-Phe-D-Pen-Arg-Arg-Ile-Arg-Pro-Cys-NH2 Mu-type opioid receptor Cavia cutleri 31 ChEMBL 10.1021/jm00049a010 10.7270/Q22N51BK 7966152 Meyer, JP; Collins, N; Lung, FD; Davis, P; Zalewska, T; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038012&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73351589 103945461 CHEMBL2370629 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037288 CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SCCSC(C)(C)[C@@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCN=C(N)N)NC1=O)C(N)=O InChI=1S/C63H101N21O12S2/c1-7-35(2)47-56(94)80-42(19-13-27-74-61(70)71)58(96)84-28-14-20-44(84)55(93)82-48(50(65)88)62(3,4)97-29-30-98-63(5,6)49(57(95)79-40(17-11-25-72-59(66)67)52(90)78-41(53(91)81-47)18-12-26-73-60(68)69)83-54(92)43(32-36-15-9-8-10-16-36)77-46(87)34-75-45(86)33-76-51(89)39(64)31-37-21-23-38(85)24-22-37/h8-10,15-16,21-24,35,39-44,47-49,85H,7,11-14,17-20,25-34,64H2,1-6H3,(H2,65,88)(H,75,86)(H,76,89)(H,77,87)(H,78,90)(H,79,95)(H,80,94)(H,81,91)(H,82,93)(H,83,92)(H4,66,67,72)(H4,68,69,73)(H4,70,71,74)/t35-,39-,40-,41-,42-,43-,44-,47-,48-,49-/m0/s1 WATVUOQHRHGCSA-DNZYPPQASA-N 50038014 CHEMBL2370622::Tyr-Gly-Gly-Phe-Cys-Arg-Arg-Ile-Arg-Pro-D-Pen-NH2 Mu-type opioid receptor Cavia cutleri 5 ChEMBL 10.1021/jm00049a010 10.7270/Q22N51BK 7966152 Meyer, JP; Collins, N; Lung, FD; Davis, P; Zalewska, T; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038014&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73350102 103945463 CHEMBL2370622 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037293 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@H](CCCCN)C(N)=O InChI=1S/C63H104N22O12/c1-5-37(4)51(59(96)82-45(20-13-29-75-63(71)72)60(97)85-30-14-21-48(85)58(95)79-42(52(66)89)17-9-10-26-64)84-55(92)44(19-12-28-74-62(69)70)80-54(91)43(18-11-27-73-61(67)68)81-56(93)46(31-36(2)3)83-57(94)47(33-38-15-7-6-8-16-38)78-50(88)35-76-49(87)34-77-53(90)41(65)32-39-22-24-40(86)25-23-39/h6-8,15-16,22-25,36-37,41-48,51,86H,5,9-14,17-21,26-35,64-65H2,1-4H3,(H2,66,89)(H,76,87)(H,77,90)(H,78,88)(H,79,95)(H,80,91)(H,81,93)(H,82,96)(H,83,94)(H,84,92)(H4,67,68,73)(H4,69,70,74)(H4,71,72,75)/t37-,41-,42+,43-,44-,45-,46-,47-,48-,51-/m0/s1 OKJAOUBQLSWUNX-ZVTOOCLDSA-N 50038019 CHEMBL411338::Tyr-Gly-Gly-Phe-D-Leu-Arg-Arg-Ile-Arg-Pro-Lys-NH2 Mu-type opioid receptor Cavia cutleri 5.2 ChEMBL 10.1021/jm00049a010 10.7270/Q22N51BK 7966152 Meyer, JP; Collins, N; Lung, FD; Davis, P; Zalewska, T; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038019&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10080153 103945468 CHEMBL411338 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037306 CC[C@H](C)[C@H]1NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](CSCCSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCN=C(N)N)NC1=O)C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C59H93N21O12S2/c1-3-33(2)47-55(91)76-40(15-9-23-70-59(66)67)56(92)80-24-10-16-44(80)54(90)77-42(48(61)84)31-93-25-26-94-32-43(53(89)75-38(13-7-21-68-57(62)63)50(86)74-39(51(87)79-47)14-8-22-69-58(64)65)78-52(88)41(28-34-11-5-4-6-12-34)73-46(83)30-71-45(82)29-72-49(85)37(60)27-35-17-19-36(81)20-18-35/h4-6,11-12,17-20,33,37-44,47,81H,3,7-10,13-16,21-32,60H2,1-2H3,(H2,61,84)(H,71,82)(H,72,85)(H,73,83)(H,74,86)(H,75,89)(H,76,91)(H,77,90)(H,78,88)(H,79,87)(H4,62,63,68)(H4,64,65,69)(H4,66,67,70)/t33-,37-,38-,39-,40-,41-,42-,43+,44-,47+/m0/s1 AVKXYIHXPWNSOJ-CRUWRZBZSA-N 50038007 CHEMBL2370626::Tyr-Gly-Gly-Phe-Cys-Arg-Arg-Ile-Arg-Pro-Pen-NH2 Mu-type opioid receptor Cavia cutleri 473 ChEMBL 10.1021/jm00049a010 10.7270/Q22N51BK 7966152 Meyer, JP; Collins, N; Lung, FD; Davis, P; Zalewska, T; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038007 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038007&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73356143 103945456 CHEMBL2370626 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037308 CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SCCSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCN=C(N)N)NC1=O)C(N)=O InChI=1S/C61H97N21O12S2/c1-5-34(2)47-55(92)78-41(17-11-25-72-60(68)69)57(94)82-26-12-18-44(82)54(91)79-43(49(63)86)33-95-27-28-96-61(3,4)48(56(93)77-39(15-9-23-70-58(64)65)51(88)76-40(52(89)80-47)16-10-24-71-59(66)67)81-53(90)42(30-35-13-7-6-8-14-35)75-46(85)32-73-45(84)31-74-50(87)38(62)29-36-19-21-37(83)22-20-36/h6-8,13-14,19-22,34,38-44,47-48,83H,5,9-12,15-18,23-33,62H2,1-4H3,(H2,63,86)(H,73,84)(H,74,87)(H,75,85)(H,76,88)(H,77,93)(H,78,92)(H,79,91)(H,80,89)(H,81,90)(H4,64,65,70)(H4,66,67,71)(H4,68,69,72)/t34-,38-,39-,40-,41-,42-,43-,44-,47-,48+/m0/s1 YQNZELNRCAEXEY-QDJFIVDUSA-N 50038009 CHEMBL2370628::Tyr-Gly-Gly-Phe-D-Pen-Arg-Arg-Ile-Arg-Pro-Pen-NH2 Mu-type opioid receptor Cavia cutleri 87 ChEMBL 10.1021/jm00049a010 10.7270/Q22N51BK 7966152 Meyer, JP; Collins, N; Lung, FD; Davis, P; Zalewska, T; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038009 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038009&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73350104 103945458 CHEMBL2370628 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037314 CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SCCSC[C@@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCN=C(N)N)NC1=O)C(N)=O InChI=1S/C61H97N21O12S2/c1-5-34(2)47-55(92)78-41(17-11-25-72-60(68)69)57(94)82-26-12-18-44(82)54(91)79-43(49(63)86)33-95-27-28-96-61(3,4)48(56(93)77-39(15-9-23-70-58(64)65)51(88)76-40(52(89)80-47)16-10-24-71-59(66)67)81-53(90)42(30-35-13-7-6-8-14-35)75-46(85)32-73-45(84)31-74-50(87)38(62)29-36-19-21-37(83)22-20-36/h6-8,13-14,19-22,34,38-44,47-48,83H,5,9-12,15-18,23-33,62H2,1-4H3,(H2,63,86)(H,73,84)(H,74,87)(H,75,85)(H,76,88)(H,77,93)(H,78,92)(H,79,91)(H,80,89)(H,81,90)(H4,64,65,70)(H4,66,67,71)(H4,68,69,72)/t34-,38-,39-,40-,41-,42-,43+,44-,47-,48-/m0/s1 YQNZELNRCAEXEY-JJULPNQFSA-N 50038010 CHEMBL2370627::Tyr-Gly-Gly-Phe-Pen-Arg-Arg-Ile-Arg-Pro-D-Pen-NH2 Mu-type opioid receptor Cavia cutleri 7.1 ChEMBL 10.1021/jm00049a010 10.7270/Q22N51BK 7966152 Meyer, JP; Collins, N; Lung, FD; Davis, P; Zalewska, T; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038010&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73353057 103945459 CHEMBL2370627 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037319 CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](CSCCSC[C@@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCN=C(N)N)NC1=O)C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C59H93N21O12S2/c1-3-33(2)47-55(91)76-40(15-9-23-70-59(66)67)56(92)80-24-10-16-44(80)54(90)77-42(48(61)84)31-93-25-26-94-32-43(53(89)75-38(13-7-21-68-57(62)63)50(86)74-39(51(87)79-47)14-8-22-69-58(64)65)78-52(88)41(28-34-11-5-4-6-12-34)73-46(83)30-71-45(82)29-72-49(85)37(60)27-35-17-19-36(81)20-18-35/h4-6,11-12,17-20,33,37-44,47,81H,3,7-10,13-16,21-32,60H2,1-2H3,(H2,61,84)(H,71,82)(H,72,85)(H,73,83)(H,74,86)(H,75,89)(H,76,91)(H,77,90)(H,78,88)(H,79,87)(H4,62,63,68)(H4,64,65,69)(H4,66,67,70)/t33-,37-,38-,39-,40-,41-,42+,43+,44-,47-/m0/s1 AVKXYIHXPWNSOJ-PNALFYTKSA-N 50038008 CHEMBL2111843::Tyr-Gly-Gly-Phe-D-Cys-Arg-Arg-Ile-Arg-Pro-D-Cys-NH2 Mu-type opioid receptor Cavia cutleri 128 ChEMBL 10.1021/jm00049a010 10.7270/Q22N51BK 7966152 Meyer, JP; Collins, N; Lung, FD; Davis, P; Zalewska, T; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038008 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038008&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71459888 103945457 CHEMBL2111843 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037324 CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SCCSC(C)(C)[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCN=C(N)N)NC1=O)C(N)=O InChI=1S/C63H101N21O12S2/c1-7-35(2)47-56(94)80-42(19-13-27-74-61(70)71)58(96)84-28-14-20-44(84)55(93)82-48(50(65)88)62(3,4)97-29-30-98-63(5,6)49(57(95)79-40(17-11-25-72-59(66)67)52(90)78-41(53(91)81-47)18-12-26-73-60(68)69)83-54(92)43(32-36-15-9-8-10-16-36)77-46(87)34-75-45(86)33-76-51(89)39(64)31-37-21-23-38(85)24-22-37/h8-10,15-16,21-24,35,39-44,47-49,85H,7,11-14,17-20,25-34,64H2,1-6H3,(H2,65,88)(H,75,86)(H,76,89)(H,77,87)(H,78,90)(H,79,95)(H,80,94)(H,81,91)(H,82,93)(H,83,92)(H4,66,67,72)(H4,68,69,73)(H4,70,71,74)/t35-,39-,40-,41-,42-,43-,44-,47-,48+,49-/m0/s1 WATVUOQHRHGCSA-GJGCAURXSA-N 50038011 CHEMBL2370612::Tyr-Gly-Gly-Phe-Pen-Arg-Arg-Ile-Arg-Pro-D-Cys-NH2 Mu-type opioid receptor Cavia cutleri 68 ChEMBL 10.1021/jm00049a010 10.7270/Q22N51BK 7966152 Meyer, JP; Collins, N; Lung, FD; Davis, P; Zalewska, T; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038011&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73350099 103945460 CHEMBL2370612 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037325 CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CSCCSC(C)(C)[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCN=C(N)N)NC1=O)C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C61H97N21O12S2/c1-5-34(2)47-56(93)78-41(17-11-25-72-60(68)69)57(94)82-26-12-18-44(82)55(92)81-48(49(63)86)61(3,4)96-28-27-95-33-43(54(91)77-39(15-9-23-70-58(64)65)51(88)76-40(52(89)80-47)16-10-24-71-59(66)67)79-53(90)42(30-35-13-7-6-8-14-35)75-46(85)32-73-45(84)31-74-50(87)38(62)29-36-19-21-37(83)22-20-36/h6-8,13-14,19-22,34,38-44,47-48,83H,5,9-12,15-18,23-33,62H2,1-4H3,(H2,63,86)(H,73,84)(H,74,87)(H,75,85)(H,76,88)(H,77,91)(H,78,93)(H,79,90)(H,80,89)(H,81,92)(H4,64,65,70)(H4,66,67,71)(H4,68,69,72)/t34-,38-,39-,40-,41-,42-,43-,44-,47-,48+/m0/s1 WJOUPUVSUGSQGN-QDJFIVDUSA-N 50038016 CHEMBL2370611::Tyr-Gly-Gly-Phe-D-Cys-Arg-Arg-Ile-Arg-Pro-Pen-NH2 Mu-type opioid receptor Cavia cutleri 17 ChEMBL 10.1021/jm00049a010 10.7270/Q22N51BK 7966152 Meyer, JP; Collins, N; Lung, FD; Davis, P; Zalewska, T; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038016 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038016&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73353056 103945465 CHEMBL2370611 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037326 CC[C@H](C)[C@H]1NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SCCSC(C)(C)[C@@H](NC(=O)[C@H]2CCCN2C(=O)[C@H](CCCN=C(N)N)NC1=O)C(N)=O InChI=1S/C63H101N21O12S2/c1-7-35(2)47-56(94)80-42(19-13-27-74-61(70)71)58(96)84-28-14-20-44(84)55(93)82-48(50(65)88)62(3,4)97-29-30-98-63(5,6)49(57(95)79-40(17-11-25-72-59(66)67)52(90)78-41(53(91)81-47)18-12-26-73-60(68)69)83-54(92)43(32-36-15-9-8-10-16-36)77-46(87)34-75-45(86)33-76-51(89)39(64)31-37-21-23-38(85)24-22-37/h8-10,15-16,21-24,35,39-44,47-49,85H,7,11-14,17-20,25-34,64H2,1-6H3,(H2,65,88)(H,75,86)(H,76,89)(H,77,87)(H,78,90)(H,79,95)(H,80,94)(H,81,91)(H,82,93)(H,83,92)(H4,66,67,72)(H4,68,69,73)(H4,70,71,74)/t35-,39-,40+,41-,42-,43-,44+,47+,48-,49+/m0/s1 WATVUOQHRHGCSA-LMSSTTIUSA-N 50038018 CHEMBL2370610::Tyr-Gly-Gly-Phe-Pen-Arg-Arg-Ile-Arg-Pro-Cys-NH2 Mu-type opioid receptor Cavia cutleri 224 ChEMBL 10.1021/jm00049a010 10.7270/Q22N51BK 7966152 Meyer, JP; Collins, N; Lung, FD; Davis, P; Zalewska, T; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038018&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73350098 103945467 CHEMBL2370610 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037327 CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](CSCCSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCN=C(N)N)NC1=O)C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C59H93N21O12S2/c1-3-33(2)47-55(91)76-40(15-9-23-70-59(66)67)56(92)80-24-10-16-44(80)54(90)77-42(48(61)84)31-93-25-26-94-32-43(53(89)75-38(13-7-21-68-57(62)63)50(86)74-39(51(87)79-47)14-8-22-69-58(64)65)78-52(88)41(28-34-11-5-4-6-12-34)73-46(83)30-71-45(82)29-72-49(85)37(60)27-35-17-19-36(81)20-18-35/h4-6,11-12,17-20,33,37-44,47,81H,3,7-10,13-16,21-32,60H2,1-2H3,(H2,61,84)(H,71,82)(H,72,85)(H,73,83)(H,74,86)(H,75,89)(H,76,91)(H,77,90)(H,78,88)(H,79,87)(H4,62,63,68)(H4,64,65,69)(H4,66,67,70)/t33-,37-,38-,39-,40-,41-,42-,43+,44-,47-/m0/s1 AVKXYIHXPWNSOJ-XGUKETMOSA-N 50453446 CHEMBL2369128 Mu-type opioid receptor Cavia cutleri 27 ChEMBL 10.1021/jm00049a010 10.7270/Q22N51BK 7966152 Meyer, JP; Collins, N; Lung, FD; Davis, P; Zalewska, T; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453446 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453446&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73348396 225145945 CHEMBL2369128 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037334 CC[C@H](C)[C@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SCCSC[C@H](NC(=O)[C@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC1=O)C(N)=O InChI=1S/C61H97N21O12S2/c1-5-34(2)47-55(92)78-41(17-11-25-72-60(68)69)57(94)82-26-12-18-44(82)54(91)79-43(49(63)86)33-95-27-28-96-61(3,4)48(56(93)77-39(15-9-23-70-58(64)65)51(88)76-40(52(89)80-47)16-10-24-71-59(66)67)81-53(90)42(30-35-13-7-6-8-14-35)75-46(85)32-73-45(84)31-74-50(87)38(62)29-36-19-21-37(83)22-20-36/h6-8,13-14,19-22,34,38-44,47-48,83H,5,9-12,15-18,23-33,62H2,1-4H3,(H2,63,86)(H,73,84)(H,74,87)(H,75,85)(H,76,88)(H,77,93)(H,78,92)(H,79,91)(H,80,89)(H,81,90)(H4,64,65,70)(H4,66,67,71)(H4,68,69,72)/t34-,38-,39+,40-,41-,42-,43-,44+,47+,48+/m0/s1 YQNZELNRCAEXEY-DHILHQQKSA-N 50038006 CHEMBL404929::Tyr-Gly-Gly-Phe-D-Pen-Arg-Arg-Ile-Arg-Pro-D-Cys-NH2 Mu-type opioid receptor Cavia cutleri 51 ChEMBL 10.1021/jm00049a010 10.7270/Q22N51BK 7966152 Meyer, JP; Collins, N; Lung, FD; Davis, P; Zalewska, T; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038006 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038006&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44350651 103945455 CHEMBL404929 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037336 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C63H104N22O12/c1-5-37(4)51(59(96)82-45(20-13-29-75-63(71)72)60(97)85-30-14-21-48(85)58(95)79-42(52(66)89)17-9-10-26-64)84-55(92)44(19-12-28-74-62(69)70)80-54(91)43(18-11-27-73-61(67)68)81-56(93)46(31-36(2)3)83-57(94)47(33-38-15-7-6-8-16-38)78-50(88)35-76-49(87)34-77-53(90)41(65)32-39-22-24-40(86)25-23-39/h6-8,15-16,22-25,36-37,41-48,51,86H,5,9-14,17-21,26-35,64-65H2,1-4H3,(H2,66,89)(H,76,87)(H,77,90)(H,78,88)(H,79,95)(H,80,91)(H,81,93)(H,82,96)(H,83,94)(H,84,92)(H4,67,68,73)(H4,69,70,74)(H4,71,72,75)/t37-,41-,42-,43-,44-,45-,46-,47-,48-,51-/m0/s1 OKJAOUBQLSWUNX-QFIUEGLPSA-N 50010704 CHEMBL216640::Dyn A(1-11)-NH2::Dynorphin A analogues::H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-NH2::HTyr-Gly-Gly-Phe-Leu-Arg-Arg-lle-Arg-Pro-LysNH2::Linear Dyn A-(1-11)NH2::Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-D-Lys-NH2::Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln-NH2 Mu-type opioid receptor Cavia cutleri 9.9 ChEMBL 10.1021/jm00049a010 10.7270/Q22N51BK 7966152 Meyer, JP; Collins, N; Lung, FD; Davis, P; Zalewska, T; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010704 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010704&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10677974 103923450 CHEMBL216640 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037337 CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CSCCSC(C)(C)[C@@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCN=C(N)N)NC1=O)C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C61H97N21O12S2/c1-5-34(2)47-56(93)78-41(17-11-25-72-60(68)69)57(94)82-26-12-18-44(82)55(92)81-48(49(63)86)61(3,4)96-28-27-95-33-43(54(91)77-39(15-9-23-70-58(64)65)51(88)76-40(52(89)80-47)16-10-24-71-59(66)67)79-53(90)42(30-35-13-7-6-8-14-35)75-46(85)32-73-45(84)31-74-50(87)38(62)29-36-19-21-37(83)22-20-36/h6-8,13-14,19-22,34,38-44,47-48,83H,5,9-12,15-18,23-33,62H2,1-4H3,(H2,63,86)(H,73,84)(H,74,87)(H,75,85)(H,76,88)(H,77,91)(H,78,93)(H,79,90)(H,80,89)(H,81,92)(H4,64,65,70)(H4,66,67,71)(H4,68,69,72)/t34-,38-,39-,40-,41-,42-,43-,44-,47-,48-/m0/s1 WJOUPUVSUGSQGN-XNCNPLRTSA-N 50038020 CHEMBL2370618::Tyr-Gly-Gly-Phe-D-Cys-Arg-Arg-Ile-Arg-Pro-Cys-NH2 Mu-type opioid receptor Cavia cutleri 5.2 ChEMBL 10.1021/jm00049a010 10.7270/Q22N51BK 7966152 Meyer, JP; Collins, N; Lung, FD; Davis, P; Zalewska, T; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038020&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73356142 103945469 CHEMBL2370618 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037341 CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CSCCSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCN=C(N)N)NC1=O)C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C59H93N21O12S2/c1-3-33(2)47-55(91)76-40(15-9-23-70-59(66)67)56(92)80-24-10-16-44(80)54(90)77-42(48(61)84)31-93-25-26-94-32-43(53(89)75-38(13-7-21-68-57(62)63)50(86)74-39(51(87)79-47)14-8-22-69-58(64)65)78-52(88)41(28-34-11-5-4-6-12-34)73-46(83)30-71-45(82)29-72-49(85)37(60)27-35-17-19-36(81)20-18-35/h4-6,11-12,17-20,33,37-44,47,81H,3,7-10,13-16,21-32,60H2,1-2H3,(H2,61,84)(H,71,82)(H,72,85)(H,73,83)(H,74,86)(H,75,89)(H,76,91)(H,77,90)(H,78,88)(H,79,87)(H4,62,63,68)(H4,64,65,69)(H4,66,67,70)/t33-,37-,38-,39-,40-,41-,42-,43-,44-,47-/m0/s1 AVKXYIHXPWNSOJ-PHACCDQDSA-N 50453445 CHEMBL2112652 Mu-type opioid receptor Cavia cutleri 12 ChEMBL 10.1021/jm00049a010 10.7270/Q22N51BK 7966152 Meyer, JP; Collins, N; Lung, FD; Davis, P; Zalewska, T; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453445&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71454476 225145944 CHEMBL2112652 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50039747 CCCCOc1c(O)ccc2CC3N(CC4CC4)CCC4(CC(=O)CC[C@@]34OC)c12 InChI=1S/C25H35NO4/c1-3-4-13-30-23-20(28)8-7-18-14-21-25(29-2)10-9-19(27)15-24(25,22(18)23)11-12-26(21)16-17-5-6-17/h7-8,17,21,28H,3-6,9-16H2,1-2H3/t21?,24?,25-/m1/s1 NDMQGMHZJUILQN-ZZVXHFGESA-N 50032528 3-butoxy-17-cyclopropylmethyl-4-hydroxy-10-methoxy-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-13-one::CHEMBL322195 Mu-type opioid receptor Cavia cutleri 11 ChEMBL 10.1021/jm00016a010 10.7270/Q2QJ7HZ2 7636870 Schmidhammer, H; Jennewein, HK; Krassnig, R; Traynor, JR; Patel, D; Bell, K; Froschauer, G; Mattersberger, K; Jachs-Ewinger, C; Jura, P University of Innsbruck http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032528 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032528&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44334707 103941026 CHEMBL322195 ZINC36221218 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50039749 COc1cccc2C[C@H]3N(CC4CC4)CC[C@@]4(CC(=O)CC[C@@]34OC)c12 InChI=1S/C22H29NO3/c1-25-18-5-3-4-16-12-19-22(26-2)9-8-17(24)13-21(22,20(16)18)10-11-23(19)14-15-6-7-15/h3-5,15,19H,6-14H2,1-2H3/t19-,21-,22-/m1/s1 INUCRGMCKDQKNA-CEMLEFRQSA-N 50148071 (-)-N-(Cycloproylmethyl)-4,14-dimethoxymorphinan-6-one(Cyprodime)::17-cyclopropylmethyl-10-hydroxy-4,14-dimethoxy-(1S,9R,10S)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3-dien-6-one(cyprodime)::17-cyclopropylmethyl-3,10-dimethoxy-(1R,9R,10S)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-13-one::CHEMBL322796::CYPRODIME BROMIDE::Naltrindole analogue::cyprodime Mu-type opioid receptor Cavia cutleri 24 ChEMBL 10.1021/jm00016a010 10.7270/Q2QJ7HZ2 7636870 Schmidhammer, H; Jennewein, HK; Krassnig, R; Traynor, JR; Patel, D; Bell, K; Froschauer, G; Mattersberger, K; Jachs-Ewinger, C; Jura, P University of Innsbruck http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50148071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50148071&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5748293 104036454 CHEMBL322796 ZINC13580323 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037596 Oc1ccc2CC3N(CC4CC4)CCC45C(Oc1c24)[C@H](CCC35O)OCc1cccc2ccccc12 InChI=1S/C31H33NO4/c33-24-11-10-21-16-26-31(34)13-12-25(35-18-22-6-3-5-20-4-1-2-7-23(20)22)29-30(31,27(21)28(24)36-29)14-15-32(26)17-19-8-9-19/h1-7,10-11,19,25-26,29,33-34H,8-9,12-18H2/t25-,26?,29?,30?,31?/m0/s1 SFXSYZVVJJLJLE-JXZAGIHRSA-N 50453483 CHEMBL2111912 Mu-type opioid receptor Cavia cutleri 1 ChEMBL 10.1021/jm00051a003 10.7270/Q2NV9JVC 7996538 Nelson, TD; Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453483&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71456180 225145953 CHEMBL2111912 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037598 Oc1ccc2CC3N(CC4CC4)CCC45C(Oc1c24)[C@H](CCC35O)OCc1ccc2ccccc2c1 InChI=1S/C31H33NO4/c33-24-10-9-23-16-26-31(34)12-11-25(35-18-20-7-8-21-3-1-2-4-22(21)15-20)29-30(31,27(23)28(24)36-29)13-14-32(26)17-19-5-6-19/h1-4,7-10,15,19,25-26,29,33-34H,5-6,11-14,16-18H2/t25-,26?,29?,30?,31?/m0/s1 ZSXCQUHBSATCCZ-JXZAGIHRSA-N 50453481 CHEMBL2111911 Mu-type opioid receptor Cavia cutleri 1.2 ChEMBL 10.1021/jm00051a003 10.7270/Q2NV9JVC 7996538 Nelson, TD; Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453481 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453481&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71454425 225145951 CHEMBL2111911 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037601 Oc1ccc2CC3N(CC4CC4)CCC45C(Oc1c24)C(CCC35O)OCC(=O)C1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2 InChI=1S/C32H41NO5/c34-23-4-3-20-14-26-32(36)6-5-25(37-16-24(35)27-21-10-18-9-19(12-21)13-22(27)11-18)30-31(32,28(20)29(23)38-30)7-8-33(26)15-17-1-2-17/h3-4,17-19,21-22,25-27,30,34,36H,1-2,5-16H2/t18-,19+,21-,22+,25?,26?,27?,30?,31?,32? CWYQQNFWYKYBDI-UGFLWSHBSA-N 50038293 17-(cyclopropylmethyl)-4,5alpha-epoxy-3,14-dihydroxy-6beta-morphinanyl 2-adamantyl-2-oxoethylether::CHEMBL423341 Mu-type opioid receptor Cavia cutleri 6.6 ChEMBL 10.1021/jm00051a003 10.7270/Q2NV9JVC 7996538 Nelson, TD; Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038293&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44356181 103945730 CHEMBL423341 ZINC72167116 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037604 CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23-,24-/m0/s1 MCMMCRYPQBNCPH-DVKRWUGUSA-N 50001683 13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid::7-Benzyl-10-{[3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL294616::DPDPE Mu-type opioid receptor Cavia cutleri 1760 ChEMBL 10.1021/jm00051a003 10.7270/Q2NV9JVC 7996538 Nelson, TD; Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001683&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299404 103916113 CHEMBL294616 ZINC27520031 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037609 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1 DQCKKXVULJGBQN-XFWGSAIBSA-N 60212 (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::MLS000069607::NALTREXONE HYDROCHLORIDE::SMR000058767::US10988481, Compound NTX::US9107954, naltrexone::cid_5485201 Mu-type opioid receptor Cavia cutleri 0.230000 ChEMBL 10.1021/jm00051a003 10.7270/Q2NV9JVC 7996538 Nelson, TD; Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60212&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5360515 252639834 DB00704 C07253 ZINC00001773 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037615 Oc1ccc2CC3N(CC4CC4)CCC45C(Oc1c24)[C@@H](CCC35O)OCc1cccc2ccccc12 InChI=1S/C31H33NO4/c33-24-11-10-21-16-26-31(34)13-12-25(35-18-22-6-3-5-20-4-1-2-7-23(20)22)29-30(31,27(21)28(24)36-29)14-15-32(26)17-19-8-9-19/h1-7,10-11,19,25-26,29,33-34H,8-9,12-18H2/t25-,26?,29?,30?,31?/m1/s1 SFXSYZVVJJLJLE-JWDZAJNQSA-N 50453486 CHEMBL2112740 Mu-type opioid receptor Cavia cutleri 3.1 ChEMBL 10.1021/jm00051a003 10.7270/Q2NV9JVC 7996538 Nelson, TD; Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453486 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453486&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71454482 225145956 CHEMBL2112740 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037616 Oc1ccc2CC3N(CC4CC4)CCC45C(Oc1c24)[C@H](CCC35O)OCc1c2ccccc2cc2ccccc12 InChI=1S/C35H35NO4/c37-28-12-11-24-18-30-35(38)14-13-29(33-34(35,31(24)32(28)40-33)15-16-36(30)19-21-9-10-21)39-20-27-25-7-3-1-5-22(25)17-23-6-2-4-8-26(23)27/h1-8,11-12,17,21,29-30,33,37-38H,9-10,13-16,18-20H2/t29-,30?,33?,34?,35?/m0/s1 IBSRUZNQVVJFNR-XGTRXYSZSA-N 50453487 CHEMBL2111916 Mu-type opioid receptor Cavia cutleri 6.6 ChEMBL 10.1021/jm00051a003 10.7270/Q2NV9JVC 7996538 Nelson, TD; Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453487 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453487&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71456182 225145957 CHEMBL2111916 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037618 Oc1ccc2CC3N(CC4CC4)CCC45C(Oc1c24)[C@H](CCC35O)OCc1ccccc1 InChI=1S/C27H31NO4/c29-20-9-8-19-14-22-27(30)11-10-21(31-16-18-4-2-1-3-5-18)25-26(27,23(19)24(20)32-25)12-13-28(22)15-17-6-7-17/h1-5,8-9,17,21-22,25,29-30H,6-7,10-16H2/t21-,22?,25?,26?,27?/m0/s1 LLYKFTJDMLXUDK-PQYJYHFLSA-N 50453485 CHEMBL2111914 Mu-type opioid receptor Cavia cutleri 0.300000 ChEMBL 10.1021/jm00051a003 10.7270/Q2NV9JVC 7996538 Nelson, TD; Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453485 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453485&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71456181 225145955 CHEMBL2111914 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037619 Oc1ccc2CC3N(CC4CC4)CCC45C(Oc1c24)[C@H](CCC35O)OCc1ccc(cc1)-c1ccccc1 InChI=1S/C33H35NO4/c35-26-13-12-25-18-28-33(36)15-14-27(37-20-22-8-10-24(11-9-22)23-4-2-1-3-5-23)31-32(33,29(25)30(26)38-31)16-17-34(28)19-21-6-7-21/h1-5,8-13,21,27-28,31,35-36H,6-7,14-20H2/t27-,28?,31?,32?,33?/m0/s1 OZBNFFZIMBTLAB-BEAPVZRPSA-N 50453484 CHEMBL2111913 Mu-type opioid receptor Cavia cutleri 10 ChEMBL 10.1021/jm00051a003 10.7270/Q2NV9JVC 7996538 Nelson, TD; Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453484&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71457978 225145954 CHEMBL2111913 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50038722 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H]1CCCCNC(=O)CNC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccc3ccccc3c2)NC1=O InChI=1S/C35H42N6O6/c36-27(19-22-11-14-26(42)15-12-22)32(44)39-28-8-3-4-16-37-31(43)21-38-34(46)30-9-5-17-41(30)35(47)29(40-33(28)45)20-23-10-13-24-6-1-2-7-25(24)18-23/h1-2,6-7,10-15,18,27-30,42H,3-5,8-9,16-17,19-21,36H2,(H,37,43)(H,38,46)(H,39,44)(H,40,45)/t27-,28-,29-,30+/m0/s1 HXRSYJPZHHJNPY-GCXHJFECSA-N 50041147 (S)-2-Amino-3-(4-hydroxy-phenyl)-N-((5S,8S,17aR)-5-naphthalen-2-ylmethyl-4,7,14,17-tetraoxo-hexadecahydro-3a,6,13,16-tetraaza-cyclopentacyclohexadecen-8-yl)-propionamide::CHEMBL274012 Mu-type opioid receptor Cavia cutleri 609 ChEMBL 10.1021/jm00034a011 10.7270/Q22Z1650 8164255 Schmidt, R; Vogel, D; Mrestani-Klaus, C; Brandt, W; Neubert, K; Chung, NN; Lemieux, C; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041147 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041147&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269823 103972991 CHEMBL274012 ZINC49600059 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50039751 COc1c(O)ccc2CC3N(CC4CC4)CCC4(CC(=O)CC[C@@]34O)c12 InChI=1S/C21H27NO4/c1-26-19-16(24)5-4-14-10-17-21(25)7-6-15(23)11-20(21,18(14)19)8-9-22(17)12-13-2-3-13/h4-5,13,17,24-25H,2-3,6-12H2,1H3/t17?,20?,21-/m1/s1 QOEVQPWLYUDAHW-FBPXKMNZSA-N 50032525 17-cyclopropylmethyl-4,10-dihydroxy-3-methoxy-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-13-one::CHEMBL104310 Mu-type opioid receptor Cavia cutleri 54 ChEMBL 10.1021/jm00016a010 10.7270/Q2QJ7HZ2 7636870 Schmidhammer, H; Jennewein, HK; Krassnig, R; Traynor, JR; Patel, D; Bell, K; Froschauer, G; Mattersberger, K; Jachs-Ewinger, C; Jura, P University of Innsbruck http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032525 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032525&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335064 103941023 CHEMBL104310 ZINC36221223 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50039755 COc1c(O)ccc2CC3N(CC=C)CCC4(CC(=O)CC[C@@]34OC)c12 InChI=1S/C21H27NO4/c1-4-10-22-11-9-20-13-15(23)7-8-21(20,26-3)17(22)12-14-5-6-16(24)19(25-2)18(14)20/h4-6,17,24H,1,7-13H2,2-3H3/t17?,20?,21-/m1/s1 MOUUUMWXJMHUKI-FBPXKMNZSA-N 50032526 17-allyl-4-hydroxy-3,10-dimethoxy-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-13-one::CHEMBL317030 Mu-type opioid receptor Cavia cutleri 7.3 ChEMBL 10.1021/jm00016a010 10.7270/Q2QJ7HZ2 7636870 Schmidhammer, H; Jennewein, HK; Krassnig, R; Traynor, JR; Patel, D; Bell, K; Froschauer, G; Mattersberger, K; Jachs-Ewinger, C; Jura, P University of Innsbruck http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032526 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032526&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44334658 103941024 CHEMBL317030 ZINC36221221 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50039760 COc1c(O)ccc2CC3N(CC4CC4)CCC4(CC(=O)CC[C@@]34OC)c12 InChI=1S/C22H29NO4/c1-26-20-17(25)6-5-15-11-18-22(27-2)8-7-16(24)12-21(22,19(15)20)9-10-23(18)13-14-3-4-14/h5-6,14,18,25H,3-4,7-13H2,1-2H3/t18?,21?,22-/m1/s1 HHLFEKGPFKSEJX-FQUBMZHMSA-N 50032530 17-cyclopropylmethyl-4-hydroxy-3,10-dimethoxy-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-13-one::CHEMBL105665 Mu-type opioid receptor Cavia cutleri 6.2 ChEMBL 10.1021/jm00016a010 10.7270/Q2QJ7HZ2 7636870 Schmidhammer, H; Jennewein, HK; Krassnig, R; Traynor, JR; Patel, D; Bell, K; Froschauer, G; Mattersberger, K; Jachs-Ewinger, C; Jura, P University of Innsbruck http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032530 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032530&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335120 103941028 CHEMBL105665 ZINC34137071 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50039761 CCO[C@@]12CCC(=O)CC11CCN(CC3CC3)C2Cc2ccc(O)c(OC)c12 InChI=1S/C23H31NO4/c1-3-28-23-9-8-17(25)13-22(23)10-11-24(14-15-4-5-15)19(23)12-16-6-7-18(26)21(27-2)20(16)22/h6-7,15,19,26H,3-5,8-14H2,1-2H3/t19?,22?,23-/m1/s1 AEDDGWOMKKVLRS-ZUEZHPSSSA-N 50032527 17-cyclopropylmethyl-10-ethoxy-4-hydroxy-3-methoxy-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-13-one::CHEMBL317269 Mu-type opioid receptor Cavia cutleri 1.4 ChEMBL 10.1021/jm00016a010 10.7270/Q2QJ7HZ2 7636870 Schmidhammer, H; Jennewein, HK; Krassnig, R; Traynor, JR; Patel, D; Bell, K; Froschauer, G; Mattersberger, K; Jachs-Ewinger, C; Jura, P University of Innsbruck http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032527 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032527&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44334636 103941025 CHEMBL317269 ZINC13742491 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50036562 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](CO)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H]([C@@H](C)O)C(O)=O InChI=1S/C33H46N6O10/c1-18(2)13-24(32(47)39-28(19(3)41)33(48)49)37-31(46)25(15-20-7-5-4-6-8-20)36-27(43)16-35-30(45)26(17-40)38-29(44)23(34)14-21-9-11-22(42)12-10-21/h4-12,18-19,23-26,28,40-42H,13-17,34H2,1-3H3,(H,35,45)(H,36,43)(H,37,46)(H,38,44)(H,39,47)(H,48,49)/t19-,23+,24+,25+,26-,28+/m1/s1 PKSODCLCMBUCPW-LVNBQDLPSA-N 50018708 2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-3-hydroxy-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-3-hydroxy-butyric acid::CHEMBL124283::DSLET::DSLET-OH::Tyr-D-Ser-Gly-Phe-Leu-Thr Mu-type opioid receptor Cavia cutleri 73 ChEMBL 10.1021/jm00044a006 10.7270/Q2513ZVF 8071934 Weerawarna, SA; Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018708 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018708&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 107847 103929785 CHEMBL124283 1609 C06396 ZINC27215004 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037633 O[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45 InChI=1S/C20H25NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,14-15,18,22-24H,1-2,5-10H2/t14-,15-,18+,19+,20-/m1/s1 JLVNEHKORQFVQJ-PYIJOLGTSA-N 50001709 4-cyclopropylmethyl-(13R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-triene-10,14,17-triol::CHEMBL140278::CHEMBL558140::Naltrexone-6-beta-ol Mu-type opioid receptor Cavia cutleri 0.500000 ChEMBL 10.1021/jm00051a003 10.7270/Q2NV9JVC 7996538 Nelson, TD; Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001709 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001709&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5486554 103916124 CHEMBL140278CHEMBL558140 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037634 Oc1ccc2CC3N(CC4CC4)CCC45C(Oc1c24)[C@@H](CCC35O)OCc1c2ccccc2cc2ccccc12 InChI=1S/C35H35NO4/c37-28-12-11-24-18-30-35(38)14-13-29(33-34(35,31(24)32(28)40-33)15-16-36(30)19-21-9-10-21)39-20-27-25-7-3-1-5-22(25)17-23-6-2-4-8-26(23)27/h1-8,11-12,17,21,29-30,33,37-38H,9-10,13-16,18-20H2/t29-,30?,33?,34?,35?/m1/s1 IBSRUZNQVVJFNR-MYNHSOFUSA-N 50453490 CHEMBL2112736 Mu-type opioid receptor Cavia cutleri 16 ChEMBL 10.1021/jm00051a003 10.7270/Q2NV9JVC 7996538 Nelson, TD; Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453490 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453490&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71452702 225145960 CHEMBL2112736 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037635 Oc1ccc2CC3N(CC4CC4)CCC45C(Oc1c24)[C@@H](CCC35O)OCc1ccccc1 InChI=1S/C27H31NO4/c29-20-9-8-19-14-22-27(30)11-10-21(31-16-18-4-2-1-3-5-18)25-26(27,23(19)24(20)32-25)12-13-28(22)15-17-6-7-17/h1-5,8-9,17,21-22,25,29-30H,6-7,10-16H2/t21-,22?,25?,26?,27?/m1/s1 LLYKFTJDMLXUDK-XVMPFKDUSA-N 50453488 CHEMBL2112732 Mu-type opioid receptor Cavia cutleri 2.4 ChEMBL 10.1021/jm00051a003 10.7270/Q2NV9JVC 7996538 Nelson, TD; Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453488 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453488&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71456227 225145958 CHEMBL2112732 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037636 Oc1ccc2CC3N(CC4CC4)CCC45C(Oc1c24)[C@@H](CCC35O)OCc1ccc2ccccc2c1 InChI=1S/C31H33NO4/c33-24-10-9-23-16-26-31(34)12-11-25(35-18-20-7-8-21-3-1-2-4-22(21)15-20)29-30(31,27(23)28(24)36-29)13-14-32(26)17-19-5-6-19/h1-4,7-10,15,19,25-26,29,33-34H,5-6,11-14,16-18H2/t25-,26?,29?,30?,31?/m1/s1 ZSXCQUHBSATCCZ-JWDZAJNQSA-N 50453482 CHEMBL2112729 Mu-type opioid receptor Cavia cutleri 1.7 ChEMBL 10.1021/jm00051a003 10.7270/Q2NV9JVC 7996538 Nelson, TD; Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453482 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453482&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71456225 225145952 CHEMBL2112729 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037637 Oc1ccc2CC3N(CC4CC4)CCC45C(Oc1c24)[C@@H](CCC35O)OCc1ccc(cc1)-c1ccccc1 InChI=1S/C33H35NO4/c35-26-13-12-25-18-28-33(36)15-14-27(37-20-22-8-10-24(11-9-22)23-4-2-1-3-5-23)31-32(33,29(25)30(26)38-31)16-17-34(28)19-21-6-7-21/h1-5,8-13,21,27-28,31,35-36H,6-7,14-20H2/t27-,28?,31?,32?,33?/m1/s1 OZBNFFZIMBTLAB-PZEBTOFLSA-N 50453489 CHEMBL2112730 Mu-type opioid receptor Cavia cutleri 0.700000 ChEMBL 10.1021/jm00051a003 10.7270/Q2NV9JVC 7996538 Nelson, TD; Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453489 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453489&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71454481 225145959 CHEMBL2112730 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50036566 CN([C@H]1C[C@@]2(CCCO2)CC[C@@H]1N1CCCC1)C(=O)Cc1ccccc1 InChI=1S/C22H32N2O2/c1-23(21(25)16-18-8-3-2-4-9-18)20-17-22(11-7-15-26-22)12-10-19(20)24-13-5-6-14-24/h2-4,8-9,19-20H,5-7,10-17H2,1H3/t19-,20-,22+/m0/s1 PGJPPWQHDNODBR-JAXLGGSGSA-N 50381677 CHEMBL1256748::U-69593 Mu-type opioid receptor Cavia cutleri 1760 ChEMBL 10.1021/jm00044a006 10.7270/Q2513ZVF 8071934 Weerawarna, SA; Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50381677 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50381677&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 52947240 160860760 CHEMBL1256748 ZINC64539951 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50036573 CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23-,24-/m0/s1 MCMMCRYPQBNCPH-DVKRWUGUSA-N 50001683 13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid::7-Benzyl-10-{[3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL294616::DPDPE Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm00044a006 10.7270/Q2513ZVF 8071934 Weerawarna, SA; Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001683&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299404 103916113 CHEMBL294616 ZINC27520031 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037770 CC1(C)SSC[C@H](NC(=O)[C@@]2(N)Cc3ccc(O)cc3C2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(O)=O InChI=1S/C27H32N4O6S2/c1-26(2)21(24(35)36)31-22(33)19(10-15-6-4-3-5-7-15)29-23(34)20(14-38-39-26)30-25(37)27(28)12-16-8-9-18(32)11-17(16)13-27/h3-9,11,19-21,32H,10,12-14,28H2,1-2H3,(H,29,34)(H,30,37)(H,31,33)(H,35,36)/t19-,20-,21+,27+/m0/s1 RKGXCVAISWNJGS-FRUANSSVSA-N 50038406 (4R,7S,10R)-10-[((R)-2-Amino-5-hydroxy-indane-2-carbonyl)-amino]-7-benzyl-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL136515 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm00051a015 10.7270/Q2CZ3660 7996549 Mosberg, HI; Lomize, AL; Wang, C; Kroona, H; Heyl, DL; Sobczyk-Kojiro, K; Ma, W; Mousigian, C; Porreca, F University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038406 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038406&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44358227 103945780 CHEMBL136515 ZINC27440278 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037771 CC1(C)SSC[C@H](NC(=O)[C@H]2NCC[C@H]2c2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(O)=O InChI=1S/C28H34N4O6S2/c1-28(2)23(27(37)38)32-24(34)20(14-16-6-4-3-5-7-16)30-25(35)21(15-39-40-28)31-26(36)22-19(12-13-29-22)17-8-10-18(33)11-9-17/h3-11,19-23,29,33H,12-15H2,1-2H3,(H,30,35)(H,31,36)(H,32,34)(H,37,38)/t19-,20-,21-,22-,23+/m0/s1 ZATPZTVNZBDUOD-XZCBWCRCSA-N 50038402 (4R,7S,10R)-7-Benzyl-10-{[(2S,3S)-3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL336657 Mu-type opioid receptor Cavia cutleri 720 ChEMBL 10.1021/jm00051a015 10.7270/Q2CZ3660 7996549 Mosberg, HI; Lomize, AL; Wang, C; Kroona, H; Heyl, DL; Sobczyk-Kojiro, K; Ma, W; Mousigian, C; Porreca, F University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038402 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038402&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44358180 103945776 CHEMBL336657 ZINC27443197 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50039942 CC[C@H](C)[C@H](NC[C@H](CCCCN)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C63H106N20O11/c1-5-39(4)53(60(93)81-47(21-14-30-73-63(70)71)61(94)83-31-15-22-50(83)59(92)79-45(54(67)87)19-10-12-28-65)75-35-42(18-9-11-27-64)77-56(89)46(20-13-29-72-62(68)69)80-57(90)48(32-38(2)3)82-58(91)49(34-40-16-7-6-8-17-40)78-52(86)37-74-51(85)36-76-55(88)44(66)33-41-23-25-43(84)26-24-41/h6-8,16-17,23-26,38-39,42,44-50,53,75,84H,5,9-15,18-22,27-37,64-66H2,1-4H3,(H2,67,87)(H,74,85)(H,76,88)(H,77,89)(H,78,86)(H,79,92)(H,80,90)(H,81,93)(H,82,91)(H4,68,69,72)(H4,70,71,73)/t39-,42-,44-,45-,46-,47-,48-,49-,50-,53-/m0/s1 QQPOIQGETZNORH-PGGYXFKHSA-N 50033141 CHEMBL2370494::H-Tyr-Gly-Gly-Phe-Leu-Arg-Lys*-Ile*-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln-OH Mu-type opioid receptor Cavia cutleri 9.2 ChEMBL 10.1021/jm00018a006 10.7270/Q2QZ291Q 7658433 Meyer, JP; Davis, P; Lee, KB; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033141&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10464136 103941475 CHEMBL2370494 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50039943 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C63H106N22O11/c1-5-38(4)52(59(95)83-47(20-13-29-75-63(71)72)60(96)85-30-14-21-49(85)58(94)80-44(53(66)89)17-9-10-26-64)84-56(92)46(19-12-28-74-62(69)70)81-55(91)45(18-11-27-73-61(67)68)82-57(93)48(31-37(2)3)76-34-41(32-39-15-7-6-8-16-39)79-51(88)36-77-50(87)35-78-54(90)43(65)33-40-22-24-42(86)25-23-40/h6-8,15-16,22-25,37-38,41,43-49,52,76,86H,5,9-14,17-21,26-36,64-65H2,1-4H3,(H2,66,89)(H,77,87)(H,78,90)(H,79,88)(H,80,94)(H,81,91)(H,82,93)(H,83,95)(H,84,92)(H4,67,68,73)(H4,69,70,74)(H4,71,72,75)/t38-,41-,43-,44-,45-,46-,47-,48-,49-,52-/m0/s1 AAPZKHUHCWNLSN-WPVLUZQDSA-N 50453783 CHEMBL2311023 Mu-type opioid receptor Cavia cutleri 12 ChEMBL 10.1021/jm00018a006 10.7270/Q2QZ291Q 7658433 Meyer, JP; Davis, P; Lee, KB; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453783 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453783&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71717290 225146111 CHEMBL2311023 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50039944 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)CN1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C63H106N20O11/c1-5-39(4)53(61(94)76-42(18-9-11-27-64)37-83-31-15-22-50(83)60(93)78-45(54(67)87)19-10-12-28-65)82-57(90)47(21-14-30-73-63(70)71)79-56(89)46(20-13-29-72-62(68)69)80-58(91)48(32-38(2)3)81-59(92)49(34-40-16-7-6-8-17-40)77-52(86)36-74-51(85)35-75-55(88)44(66)33-41-23-25-43(84)26-24-41/h6-8,16-17,23-26,38-39,42,44-50,53,84H,5,9-15,18-22,27-37,64-66H2,1-4H3,(H2,67,87)(H,74,85)(H,75,88)(H,76,94)(H,77,86)(H,78,93)(H,79,89)(H,80,91)(H,81,92)(H,82,90)(H4,68,69,72)(H4,70,71,73)/t39-,42-,44-,45-,46-,47-,48-,49-,50-,53-/m0/s1 VNNOAPBNQWNWSP-PGGYXFKHSA-N 50033139 CHEMBL2370495::H-Tyr-Gly-Gly-Phe-Leu-Arg-Lys-Ile*-Arg*-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln-OH Mu-type opioid receptor Cavia cutleri 5.2 ChEMBL 10.1021/jm00018a006 10.7270/Q2QZ291Q 7658433 Meyer, JP; Davis, P; Lee, KB; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033139 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033139&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73353046 103941473 CHEMBL2370495 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50039945 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C63H106N22O11/c1-5-38(4)52(59(95)82-46(20-13-29-76-63(71)72)60(96)85-30-14-21-49(85)58(94)79-43(53(66)89)17-9-10-26-64)84-55(91)45(19-12-28-75-62(69)70)80-54(90)44(18-11-27-74-61(67)68)81-56(92)47(31-37(2)3)83-57(93)48(33-39-15-7-6-8-16-39)78-51(88)36-77-50(87)35-73-34-41(65)32-40-22-24-42(86)25-23-40/h6-8,15-16,22-25,37-38,41,43-49,52,73,86H,5,9-14,17-21,26-36,64-65H2,1-4H3,(H2,66,89)(H,77,87)(H,78,88)(H,79,94)(H,80,90)(H,81,92)(H,82,95)(H,83,93)(H,84,91)(H4,67,68,74)(H4,69,70,75)(H4,71,72,76)/t38-,41-,43-,44-,45-,46-,47-,48-,49-,52-/m0/s1 ZGDVJSJVDHYWCU-WPVLUZQDSA-N 50453784 CHEMBL2311024 Mu-type opioid receptor Cavia cutleri 96 ChEMBL 10.1021/jm00018a006 10.7270/Q2QZ291Q 7658433 Meyer, JP; Davis, P; Lee, KB; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453784&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71719730 225146112 CHEMBL2311024 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50039946 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C63H106N22O11/c1-5-38(4)52(59(95)83-47(20-13-29-75-63(71)72)60(96)85-30-14-21-49(85)58(94)81-44(53(66)89)17-9-10-26-64)84-56(92)46(19-12-28-74-62(69)70)82-55(91)45(18-11-27-73-61(67)68)76-34-41(31-37(2)3)79-57(93)48(33-39-15-7-6-8-16-39)80-51(88)36-77-50(87)35-78-54(90)43(65)32-40-22-24-42(86)25-23-40/h6-8,15-16,22-25,37-38,41,43-49,52,76,86H,5,9-14,17-21,26-36,64-65H2,1-4H3,(H2,66,89)(H,77,87)(H,78,90)(H,79,93)(H,80,88)(H,81,94)(H,82,91)(H,83,95)(H,84,92)(H4,67,68,73)(H4,69,70,74)(H4,71,72,75)/t38-,41-,43-,44-,45-,46-,47-,48-,49-,52-/m0/s1 KEKDAHGCQWGQQA-WPVLUZQDSA-N 50453785 CHEMBL2311025 Mu-type opioid receptor Cavia cutleri 0.640000 ChEMBL 10.1021/jm00018a006 10.7270/Q2QZ291Q 7658433 Meyer, JP; Davis, P; Lee, KB; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453785&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71718530 225146113 CHEMBL2311025 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50039952 CC[C@H](C)[C@@H](CN[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C63H106N22O11/c1-5-38(4)49(34-76-46(20-13-29-75-63(71)72)60(96)85-30-14-21-50(85)59(95)80-43(53(66)89)17-9-10-26-64)84-56(92)45(19-12-28-74-62(69)70)81-55(91)44(18-11-27-73-61(67)68)82-57(93)47(31-37(2)3)83-58(94)48(33-39-15-7-6-8-16-39)79-52(88)36-77-51(87)35-78-54(90)42(65)32-40-22-24-41(86)25-23-40/h6-8,15-16,22-25,37-38,42-50,76,86H,5,9-14,17-21,26-36,64-65H2,1-4H3,(H2,66,89)(H,77,87)(H,78,90)(H,79,88)(H,80,95)(H,81,91)(H,82,93)(H,83,94)(H,84,92)(H4,67,68,73)(H4,69,70,74)(H4,71,72,75)/t38-,42-,43-,44-,45-,46-,47-,48-,49+,50-/m0/s1 KRYGXADEBDIESF-KCTDGSTESA-N 50033142 CHEMBL2370496::H-Tyr-Gly-Gly-Phe-Leu-Lys*-Arg*-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln-OH Mu-type opioid receptor Cavia cutleri 4 ChEMBL 10.1021/jm00018a006 10.7270/Q2QZ291Q 7658433 Meyer, JP; Davis, P; Lee, KB; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033142&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73351578 103941476 CHEMBL2370496 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50039953 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC[C@H](CCCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C63H107N23O11/c1-3-38(2)52(59(96)84-47(21-13-31-76-63(72)73)60(97)86-32-14-22-49(86)58(95)82-44(53(67)90)18-8-10-28-65)85-56(93)46(20-12-30-75-62(70)71)83-55(92)45(19-11-29-74-61(68)69)77-35-41(17-7-9-27-64)80-57(94)48(34-39-15-5-4-6-16-39)81-51(89)37-78-50(88)36-79-54(91)43(66)33-40-23-25-42(87)26-24-40/h4-6,15-16,23-26,38,41,43-49,52,77,87H,3,7-14,17-22,27-37,64-66H2,1-2H3,(H2,67,90)(H,78,88)(H,79,91)(H,80,94)(H,81,89)(H,82,95)(H,83,92)(H,84,96)(H,85,93)(H4,68,69,74)(H4,70,71,75)(H4,72,73,76)/t38-,41-,43-,44-,45-,46-,47-,48-,49-,52-/m0/s1 ANJXEKUKGCQXNN-WPVLUZQDSA-N 50453782 CHEMBL2370497 Mu-type opioid receptor Cavia cutleri 9 ChEMBL 10.1021/jm00018a006 10.7270/Q2QZ291Q 7658433 Meyer, JP; Davis, P; Lee, KB; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453782&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73356135 225146110 CHEMBL2370497 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50039959 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NCCNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C63H106N22O11/c1-5-38(4)51(59(95)82-46(20-13-29-77-63(71)72)60(96)85-32-14-21-49(85)58(94)79-43(52(66)88)17-9-10-26-64)84-55(91)45(19-12-28-76-62(69)70)80-54(90)44(18-11-27-75-61(67)68)81-57(93)48(33-37(2)3)83-56(92)47(35-39-15-7-6-8-16-39)73-30-31-74-50(87)36-78-53(89)42(65)34-40-22-24-41(86)25-23-40/h6-8,15-16,22-25,37-38,42-49,51,73,86H,5,9-14,17-21,26-36,64-65H2,1-4H3,(H2,66,88)(H,74,87)(H,78,89)(H,79,94)(H,80,90)(H,81,93)(H,82,95)(H,83,92)(H,84,91)(H4,67,68,75)(H4,69,70,76)(H4,71,72,77)/t38-,42-,43-,44-,45-,46-,47-,48-,49-,51-/m0/s1 ZIIJZNDBDMLLKR-KMEINJDZSA-N 50033137 CHEMBL2311022::H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln-OH Mu-type opioid receptor Cavia cutleri 1035 ChEMBL 10.1021/jm00018a006 10.7270/Q2QZ291Q 7658433 Meyer, JP; Davis, P; Lee, KB; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033137 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033137&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71720342 103941471 CHEMBL2311022 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037774 CC1(C)SSC[C@H](NC(=O)[C@H]2NCC[C@H]2c2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(O)=O InChI=1S/C28H34N4O6S2/c1-28(2)23(27(37)38)32-24(34)20(14-16-6-4-3-5-7-16)30-25(35)21(15-39-40-28)31-26(36)22-19(12-13-29-22)17-8-10-18(33)11-9-17/h3-11,19-23,29,33H,12-15H2,1-2H3,(H,30,35)(H,31,36)(H,32,34)(H,37,38)/t19-,20-,21-,22-,23+/m0/s1 ZATPZTVNZBDUOD-XZCBWCRCSA-N 50038402 (4R,7S,10R)-7-Benzyl-10-{[(2S,3S)-3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL336657 Mu-type opioid receptor Cavia cutleri 12000 ChEMBL 10.1021/jm00051a015 10.7270/Q2CZ3660 7996549 Mosberg, HI; Lomize, AL; Wang, C; Kroona, H; Heyl, DL; Sobczyk-Kojiro, K; Ma, W; Mousigian, C; Porreca, F University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038402 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038402&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44358180 103945776 CHEMBL336657 ZINC27443197 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037778 CC1(C)SSC[C@H](NC(=O)[C@H]2NCC[C@@H]2c2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(O)=O InChI=1S/C28H34N4O6S2/c1-28(2)23(27(37)38)32-24(34)20(14-16-6-4-3-5-7-16)30-25(35)21(15-39-40-28)31-26(36)22-19(12-13-29-22)17-8-10-18(33)11-9-17/h3-11,19-23,29,33H,12-15H2,1-2H3,(H,30,35)(H,31,36)(H,32,34)(H,37,38)/t19-,20+,21+,22+,23-/m1/s1 ZATPZTVNZBDUOD-OOYIDZMOSA-N 50038405 (4R,7S,10R)-7-Benzyl-10-{[(2S,3R)-3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL343342 Mu-type opioid receptor Cavia cutleri 770 ChEMBL 10.1021/jm00051a015 10.7270/Q2CZ3660 7996549 Mosberg, HI; Lomize, AL; Wang, C; Kroona, H; Heyl, DL; Sobczyk-Kojiro, K; Ma, W; Mousigian, C; Porreca, F University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038405 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038405&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44358141 103945779 CHEMBL343342 ZINC27432579 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037780 CC1(C)SSC[C@H](NC(=O)[C@@H]2Cc3ccc(O)cc3CN2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(O)=O InChI=1S/C27H32N4O6S2/c1-27(2)22(26(36)37)31-24(34)20(10-15-6-4-3-5-7-15)29-25(35)21(14-38-39-27)30-23(33)19-12-16-8-9-18(32)11-17(16)13-28-19/h3-9,11,19-22,28,32H,10,12-14H2,1-2H3,(H,29,35)(H,30,33)(H,31,34)(H,36,37)/t19-,20-,21-,22+/m0/s1 XUZPZJFWHROOFS-MYGLTJDJSA-N 50038409 (4R,7S,10R)-7-Benzyl-10-[((S)-7-hydroxy-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl)-amino]-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL136646 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm00051a015 10.7270/Q2CZ3660 7996549 Mosberg, HI; Lomize, AL; Wang, C; Kroona, H; Heyl, DL; Sobczyk-Kojiro, K; Ma, W; Mousigian, C; Porreca, F University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038409 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038409&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44358228 103945783 CHEMBL136646 ZINC27440284 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037781 CC1(C)SSC[C@H](NC(=O)[C@@]2(N)Cc3ccc(O)cc3C2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(O)=O InChI=1S/C27H32N4O6S2/c1-26(2)21(24(35)36)31-22(33)19(10-15-6-4-3-5-7-15)29-23(34)20(14-38-39-26)30-25(37)27(28)12-16-8-9-18(32)11-17(16)13-27/h3-9,11,19-21,32H,10,12-14,28H2,1-2H3,(H,29,34)(H,30,37)(H,31,33)(H,35,36)/t19-,20-,21+,27+/m0/s1 RKGXCVAISWNJGS-FRUANSSVSA-N 50038406 (4R,7S,10R)-10-[((R)-2-Amino-5-hydroxy-indane-2-carbonyl)-amino]-7-benzyl-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL136515 Mu-type opioid receptor Cavia cutleri 840 ChEMBL 10.1021/jm00051a015 10.7270/Q2CZ3660 7996549 Mosberg, HI; Lomize, AL; Wang, C; Kroona, H; Heyl, DL; Sobczyk-Kojiro, K; Ma, W; Mousigian, C; Porreca, F University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038406 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038406&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44358227 103945780 CHEMBL136515 ZINC27440278 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037782 CC1(C)SSC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(O)=O InChI=1S/C26H32N4O6S2/c1-26(2)21(25(35)36)30-23(33)19(13-15-6-4-3-5-7-15)28-24(34)20(14-37-38-26)29-22(32)18(27)12-16-8-10-17(31)11-9-16/h3-11,18-21,31H,12-14,27H2,1-2H3,(H,28,34)(H,29,32)(H,30,33)(H,35,36)/t18-,19-,20-,21+/m0/s1 BLNPATOSLCUUSL-XSDIEEQYSA-N 50000655 (4R,7S,10R)-10-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL39192 Mu-type opioid receptor Cavia cutleri 52 ChEMBL 10.1021/jm00051a015 10.7270/Q2CZ3660 7996549 Mosberg, HI; Lomize, AL; Wang, C; Kroona, H; Heyl, DL; Sobczyk-Kojiro, K; Ma, W; Mousigian, C; Porreca, F University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000655 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000655&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44285718 103915203 CHEMBL39192 ZINC26648527 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037783 CC1(C)SSC[C@H](NC(=O)[C@]2(N)CCc3cc(O)ccc3C2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(O)=O InChI=1S/C28H34N4O6S2/c1-27(2)22(25(36)37)32-23(34)20(12-16-6-4-3-5-7-16)30-24(35)21(15-39-40-27)31-26(38)28(29)11-10-17-13-19(33)9-8-18(17)14-28/h3-9,13,20-22,33H,10-12,14-15,29H2,1-2H3,(H,30,35)(H,31,38)(H,32,34)(H,36,37)/t20-,21-,22+,28-/m0/s1 YPQPSKVGWWFRCZ-WENLUUPESA-N 50038404 (4R,7S,10R)-10-[((S)-2-Amino-6-hydroxy-1,2,3,4-tetrahydro-naphthalene-2-carbonyl)-amino]-7-benzyl-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL337265 Mu-type opioid receptor Cavia cutleri 1800 ChEMBL 10.1021/jm00051a015 10.7270/Q2CZ3660 7996549 Mosberg, HI; Lomize, AL; Wang, C; Kroona, H; Heyl, DL; Sobczyk-Kojiro, K; Ma, W; Mousigian, C; Porreca, F University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038404 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038404&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44358147 103945778 CHEMBL337265 ZINC27438969 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037786 CC1(C)SSC[C@H](NC(=O)[C@@]2(N)CCc3cc(O)ccc3C2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(O)=O InChI=1S/C28H34N4O6S2/c1-27(2)22(25(36)37)32-23(34)20(12-16-6-4-3-5-7-16)30-24(35)21(15-39-40-27)31-26(38)28(29)11-10-17-13-19(33)9-8-18(17)14-28/h3-9,13,20-22,33H,10-12,14-15,29H2,1-2H3,(H,30,35)(H,31,38)(H,32,34)(H,36,37)/t20-,21-,22+,28+/m0/s1 YPQPSKVGWWFRCZ-SXKDZKFMSA-N 50453515 CHEMBL2111933 Mu-type opioid receptor Cavia cutleri 4300 ChEMBL 10.1021/jm00051a015 10.7270/Q2CZ3660 7996549 Mosberg, HI; Lomize, AL; Wang, C; Kroona, H; Heyl, DL; Sobczyk-Kojiro, K; Ma, W; Mousigian, C; Porreca, F University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453515 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453515&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71461596 225145977 CHEMBL2111933 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037788 CC1(C)SSC[C@H](NC(=O)[C@@]2(N)CCc3cc(O)ccc3C2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(O)=O InChI=1S/C28H34N4O6S2/c1-27(2)22(25(36)37)32-23(34)20(12-16-6-4-3-5-7-16)30-24(35)21(15-39-40-27)31-26(38)28(29)11-10-17-13-19(33)9-8-18(17)14-28/h3-9,13,20-22,33H,10-12,14-15,29H2,1-2H3,(H,30,35)(H,31,38)(H,32,34)(H,36,37)/t20-,21-,22+,28+/m0/s1 YPQPSKVGWWFRCZ-SXKDZKFMSA-N 50453515 CHEMBL2111933 Mu-type opioid receptor Cavia cutleri 310 ChEMBL 10.1021/jm00051a015 10.7270/Q2CZ3660 7996549 Mosberg, HI; Lomize, AL; Wang, C; Kroona, H; Heyl, DL; Sobczyk-Kojiro, K; Ma, W; Mousigian, C; Porreca, F University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453515 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453515&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71461596 225145977 CHEMBL2111933 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037789 CC1(C)SSC[C@H](NC(=O)[C@@H]2NCC[C@@H]2c2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(O)=O InChI=1S/C28H34N4O6S2/c1-28(2)23(27(37)38)32-24(34)20(14-16-6-4-3-5-7-16)30-25(35)21(15-39-40-28)31-26(36)22-19(12-13-29-22)17-8-10-18(33)11-9-17/h3-11,19-23,29,33H,12-15H2,1-2H3,(H,30,35)(H,31,36)(H,32,34)(H,37,38)/t19-,20+,21+,22-,23-/m1/s1 ZATPZTVNZBDUOD-BMXMUORJSA-N 50453517 CHEMBL2111934 Mu-type opioid receptor Cavia cutleri 10000 ChEMBL 10.1021/jm00051a015 10.7270/Q2CZ3660 7996549 Mosberg, HI; Lomize, AL; Wang, C; Kroona, H; Heyl, DL; Sobczyk-Kojiro, K; Ma, W; Mousigian, C; Porreca, F University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453517 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453517&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71454426 225145979 CHEMBL2111934 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037790 CC1(C)SSC[C@H](NC(=O)[C@@H]2NCC[C@H]2c2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(O)=O InChI=1S/C28H34N4O6S2/c1-28(2)23(27(37)38)32-24(34)20(14-16-6-4-3-5-7-16)30-25(35)21(15-39-40-28)31-26(36)22-19(12-13-29-22)17-8-10-18(33)11-9-17/h3-11,19-23,29,33H,12-15H2,1-2H3,(H,30,35)(H,31,36)(H,32,34)(H,37,38)/t19-,20-,21-,22+,23+/m0/s1 ZATPZTVNZBDUOD-IACLWVNRSA-N 50453516 CHEMBL2111935 Mu-type opioid receptor Cavia cutleri 4440 ChEMBL 10.1021/jm00051a015 10.7270/Q2CZ3660 7996549 Mosberg, HI; Lomize, AL; Wang, C; Kroona, H; Heyl, DL; Sobczyk-Kojiro, K; Ma, W; Mousigian, C; Porreca, F University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453516 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453516&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71459892 225145978 CHEMBL2111935 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037791 CC1(C)SSC[C@H](NC(=O)[C@]2(N)CCc3cc(O)ccc3C2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(O)=O InChI=1S/C28H34N4O6S2/c1-27(2)22(25(36)37)32-23(34)20(12-16-6-4-3-5-7-16)30-24(35)21(15-39-40-27)31-26(38)28(29)11-10-17-13-19(33)9-8-18(17)14-28/h3-9,13,20-22,33H,10-12,14-15,29H2,1-2H3,(H,30,35)(H,31,38)(H,32,34)(H,36,37)/t20-,21-,22+,28-/m0/s1 YPQPSKVGWWFRCZ-WENLUUPESA-N 50038404 (4R,7S,10R)-10-[((S)-2-Amino-6-hydroxy-1,2,3,4-tetrahydro-naphthalene-2-carbonyl)-amino]-7-benzyl-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL337265 Mu-type opioid receptor Cavia cutleri 230 ChEMBL 10.1021/jm00051a015 10.7270/Q2CZ3660 7996549 Mosberg, HI; Lomize, AL; Wang, C; Kroona, H; Heyl, DL; Sobczyk-Kojiro, K; Ma, W; Mousigian, C; Porreca, F University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038404 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038404&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44358147 103945778 CHEMBL337265 ZINC27438969 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037792 CC1(C)SSC[C@H](NC(=O)[C@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(O)=O InChI=1S/C26H32N4O6S2/c1-26(2)21(25(35)36)30-23(33)19(13-15-6-4-3-5-7-15)28-24(34)20(14-37-38-26)29-22(32)18(27)12-16-8-10-17(31)11-9-16/h3-11,18-21,31H,12-14,27H2,1-2H3,(H,28,34)(H,29,32)(H,30,33)(H,35,36)/t18-,19+,20+,21-/m1/s1 BLNPATOSLCUUSL-IVAOSVALSA-N 50038408 (4R,7S,10R)-10-[(R)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL434616 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm00051a015 10.7270/Q2CZ3660 7996549 Mosberg, HI; Lomize, AL; Wang, C; Kroona, H; Heyl, DL; Sobczyk-Kojiro, K; Ma, W; Mousigian, C; Porreca, F University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038408 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038408&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44358216 103945782 CHEMBL434616 ZINC26648537 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037793 CC1(C)SSC[C@H](NC(=O)[C@H]2NCC[C@@H]2c2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(O)=O InChI=1S/C28H34N4O6S2/c1-28(2)23(27(37)38)32-24(34)20(14-16-6-4-3-5-7-16)30-25(35)21(15-39-40-28)31-26(36)22-19(12-13-29-22)17-8-10-18(33)11-9-17/h3-11,19-23,29,33H,12-15H2,1-2H3,(H,30,35)(H,31,36)(H,32,34)(H,37,38)/t19-,20+,21+,22+,23-/m1/s1 ZATPZTVNZBDUOD-OOYIDZMOSA-N 50038405 (4R,7S,10R)-7-Benzyl-10-{[(2S,3R)-3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL343342 Mu-type opioid receptor Cavia cutleri 110 ChEMBL 10.1021/jm00051a015 10.7270/Q2CZ3660 7996549 Mosberg, HI; Lomize, AL; Wang, C; Kroona, H; Heyl, DL; Sobczyk-Kojiro, K; Ma, W; Mousigian, C; Porreca, F University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038405 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038405&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44358141 103945779 CHEMBL343342 ZINC27432579 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037794 CC1(C)SSC[C@H](NC(=O)[C@]2(N)Cc3ccc(O)cc3C2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(O)=O InChI=1S/C27H32N4O6S2/c1-26(2)21(24(35)36)31-22(33)19(10-15-6-4-3-5-7-15)29-23(34)20(14-38-39-26)30-25(37)27(28)12-16-8-9-18(32)11-17(16)13-27/h3-9,11,19-21,32H,10,12-14,28H2,1-2H3,(H,29,34)(H,30,37)(H,31,33)(H,35,36)/t19-,20-,21+,27-/m0/s1 RKGXCVAISWNJGS-GRWWNZOSSA-N 50453518 CHEMBL2111936 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm00051a015 10.7270/Q2CZ3660 7996549 Mosberg, HI; Lomize, AL; Wang, C; Kroona, H; Heyl, DL; Sobczyk-Kojiro, K; Ma, W; Mousigian, C; Porreca, F University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453518&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71459893 225145980 CHEMBL2111936 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037795 C[C@](N)(Cc1ccc(O)cc1)C(=O)N[C@H]1CSSC(C)(C)[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O InChI=1S/C27H34N4O6S2/c1-26(2)21(24(35)36)31-22(33)19(13-16-7-5-4-6-8-16)29-23(34)20(15-38-39-26)30-25(37)27(3,28)14-17-9-11-18(32)12-10-17/h4-12,19-21,32H,13-15,28H2,1-3H3,(H,29,34)(H,30,37)(H,31,33)(H,35,36)/t19-,20-,21+,27-/m0/s1 DZDGITMVDYGNLE-GRWWNZOSSA-N 50038407 (4R,7S,10R)-10-[(S)-2-Amino-3-(4-hydroxy-phenyl)-2-methyl-propionylamino]-7-benzyl-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL336019 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm00051a015 10.7270/Q2CZ3660 7996549 Mosberg, HI; Lomize, AL; Wang, C; Kroona, H; Heyl, DL; Sobczyk-Kojiro, K; Ma, W; Mousigian, C; Porreca, F University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038407 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038407&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44358215 103945781 CHEMBL336019 ZINC27437806 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037797 CN[C@H](Cc1ccc(O)cc1)C(=O)N[C@H]1CSSC(C)(C)[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O InChI=1S/C27H34N4O6S2/c1-27(2)22(26(36)37)31-24(34)20(14-16-7-5-4-6-8-16)29-25(35)21(15-38-39-27)30-23(33)19(28-3)13-17-9-11-18(32)12-10-17/h4-12,19-22,28,32H,13-15H2,1-3H3,(H,29,35)(H,30,33)(H,31,34)(H,36,37)/t19-,20+,21+,22-/m1/s1 JWXHDRKYNVTFGQ-CLAROIROSA-N 50038403 (4R,7S,10R)-7-Benzyl-10-[(R)-3-(4-hydroxy-phenyl)-2-methylamino-propionylamino]-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL423903 Mu-type opioid receptor Cavia cutleri 480 ChEMBL 10.1021/jm00051a015 10.7270/Q2CZ3660 7996549 Mosberg, HI; Lomize, AL; Wang, C; Kroona, H; Heyl, DL; Sobczyk-Kojiro, K; Ma, W; Mousigian, C; Porreca, F University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038403 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038403&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44358105 103945777 CHEMBL423903 ZINC27440388 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037798 CC1(C)SSC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(O)=O InChI=1S/C26H32N4O6S2/c1-26(2)21(25(35)36)30-23(33)19(13-15-6-4-3-5-7-15)28-24(34)20(14-37-38-26)29-22(32)18(27)12-16-8-10-17(31)11-9-16/h3-11,18-21,31H,12-14,27H2,1-2H3,(H,28,34)(H,29,32)(H,30,33)(H,35,36)/t18-,19-,20-,21+/m0/s1 BLNPATOSLCUUSL-XSDIEEQYSA-N 50000655 (4R,7S,10R)-10-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL39192 Mu-type opioid receptor Cavia cutleri 460 ChEMBL 10.1021/jm00051a015 10.7270/Q2CZ3660 7996549 Mosberg, HI; Lomize, AL; Wang, C; Kroona, H; Heyl, DL; Sobczyk-Kojiro, K; Ma, W; Mousigian, C; Porreca, F University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000655 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000655&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44285718 103915203 CHEMBL39192 ZINC26648527 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037799 CN[C@H](Cc1ccc(O)cc1)C(=O)N[C@H]1CSSC(C)(C)[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O InChI=1S/C27H34N4O6S2/c1-27(2)22(26(36)37)31-24(34)20(14-16-7-5-4-6-8-16)29-25(35)21(15-38-39-27)30-23(33)19(28-3)13-17-9-11-18(32)12-10-17/h4-12,19-22,28,32H,13-15H2,1-3H3,(H,29,35)(H,30,33)(H,31,34)(H,36,37)/t19-,20+,21+,22-/m1/s1 JWXHDRKYNVTFGQ-CLAROIROSA-N 50038403 (4R,7S,10R)-7-Benzyl-10-[(R)-3-(4-hydroxy-phenyl)-2-methylamino-propionylamino]-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL423903 Mu-type opioid receptor Cavia cutleri 180 ChEMBL 10.1021/jm00051a015 10.7270/Q2CZ3660 7996549 Mosberg, HI; Lomize, AL; Wang, C; Kroona, H; Heyl, DL; Sobczyk-Kojiro, K; Ma, W; Mousigian, C; Porreca, F University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038403 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038403&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44358105 103945777 CHEMBL423903 ZINC27440388 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037801 CN1[C@@H](Cc2ccccc2)C(=O)N[C@@H](C(=O)N([C@@H](CS)C1=O)C(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)(C)S InChI=1S/C27H34N4O5S2/c1-27(2,38)22-26(36)31(24(34)19(28)13-17-9-11-18(32)12-10-17)21(15-37)25(35)30(3)20(23(33)29-22)14-16-7-5-4-6-8-16/h4-12,19-22,32,37-38H,13-15,28H2,1-3H3,(H,29,33)/t19-,20-,21-,22-/m0/s1 FFEQWDXRKVWQPI-CMOCDZPBSA-N 50038410 4-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-9-benzyl-3-mercaptomethyl-6-(1-mercapto-1-methyl-ethyl)-1-methyl-[1,4,7]triazonane-2,5,8-trione::CHEMBL2370834 Mu-type opioid receptor Cavia cutleri 3730 ChEMBL 10.1021/jm00051a016 10.7270/Q2862FH1 7996550 Mosberg, HI; Omnaas, JR; Lomize, A; Heyl, DL; Nordan, I; Mousigian, C; Davis, P; Porreca, F University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038410 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038410&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73345504 103945784 CHEMBL2370834 ZINC36221982 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037802 CN1[C@@H](Cc2ccccc2)C(=O)N[C@@H](C(=O)N([C@@H](CS)C1=O)C(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)(C)S InChI=1S/C27H34N4O5S2/c1-27(2,38)22-26(36)31(24(34)19(28)13-17-9-11-18(32)12-10-17)21(15-37)25(35)30(3)20(23(33)29-22)14-16-7-5-4-6-8-16/h4-12,19-22,32,37-38H,13-15,28H2,1-3H3,(H,29,33)/t19-,20-,21-,22-/m0/s1 FFEQWDXRKVWQPI-CMOCDZPBSA-N 50038410 4-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-9-benzyl-3-mercaptomethyl-6-(1-mercapto-1-methyl-ethyl)-1-methyl-[1,4,7]triazonane-2,5,8-trione::CHEMBL2370834 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm00051a016 10.7270/Q2862FH1 7996550 Mosberg, HI; Omnaas, JR; Lomize, A; Heyl, DL; Nordan, I; Mousigian, C; Davis, P; Porreca, F University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038410 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038410&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73345504 103945784 CHEMBL2370834 ZINC36221982 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037803 CC(C)(S)[C@H]1NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CS)N(C(=O)[C@@H](N)Cc2ccc(O)cc2)C1=O InChI=1S/C26H32N4O5S2/c1-26(2,37)21-25(35)30(24(34)18(27)12-16-8-10-17(31)11-9-16)20(14-36)23(33)28-19(22(32)29-21)13-15-6-4-3-5-7-15/h3-11,18-21,31,36-37H,12-14,27H2,1-2H3,(H,28,33)(H,29,32)/t18-,19+,20-,21-/m0/s1 SZAZZVFPYPEPBV-WOZUAGRISA-N 50453519 CHEMBL2370835 Mu-type opioid receptor Cavia cutleri 2530 ChEMBL 10.1021/jm00051a016 10.7270/Q2862FH1 7996550 Mosberg, HI; Omnaas, JR; Lomize, A; Heyl, DL; Nordan, I; Mousigian, C; Davis, P; Porreca, F University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453519 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453519&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73347037 225145981 CHEMBL2370835 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037804 CC(C)(S)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CS)N(C(=O)[C@@H](N)Cc2ccc(O)cc2)C1=O InChI=1S/C26H32N4O5S2/c1-26(2,37)21-25(35)30(24(34)18(27)12-16-8-10-17(31)11-9-16)20(14-36)23(33)28-19(22(32)29-21)13-15-6-4-3-5-7-15/h3-11,18-21,31,36-37H,12-14,27H2,1-2H3,(H,28,33)(H,29,32)/t18-,19-,20-,21+/m0/s1 SZAZZVFPYPEPBV-XSDIEEQYSA-N 50038411 1-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-6-benzyl-9-mercaptomethyl-3-(1-mercapto-1-methyl-ethyl)-[1,4,7]triazonane-2,5,8-trione::CHEMBL2369137 Mu-type opioid receptor Cavia cutleri 463 ChEMBL 10.1021/jm00051a016 10.7270/Q2862FH1 7996550 Mosberg, HI; Omnaas, JR; Lomize, A; Heyl, DL; Nordan, I; Mousigian, C; Davis, P; Porreca, F University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038411 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038411&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73351472 103945785 CHEMBL2369137 ZINC36221990 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037805 CC(C)(S)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CS)N(C(=O)[C@@H](N)Cc2ccc(O)cc2)C1=O InChI=1S/C26H32N4O5S2/c1-26(2,37)21-25(35)30(24(34)18(27)12-16-8-10-17(31)11-9-16)20(14-36)23(33)28-19(22(32)29-21)13-15-6-4-3-5-7-15/h3-11,18-21,31,36-37H,12-14,27H2,1-2H3,(H,28,33)(H,29,32)/t18-,19-,20-,21+/m0/s1 SZAZZVFPYPEPBV-XSDIEEQYSA-N 50038411 1-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-6-benzyl-9-mercaptomethyl-3-(1-mercapto-1-methyl-ethyl)-[1,4,7]triazonane-2,5,8-trione::CHEMBL2369137 Mu-type opioid receptor Cavia cutleri 52 ChEMBL 10.1021/jm00051a016 10.7270/Q2862FH1 7996550 Mosberg, HI; Omnaas, JR; Lomize, A; Heyl, DL; Nordan, I; Mousigian, C; Davis, P; Porreca, F University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038411 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038411&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73351472 103945785 CHEMBL2369137 ZINC36221990 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037809 CN1[C@@H](Cc2ccccc2)C(=O)N[C@@H](C(=O)N([C@@H](CS)C1=O)C(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)(C)S InChI=1S/C27H34N4O5S2/c1-27(2,38)22-26(36)31(24(34)19(28)13-17-9-11-18(32)12-10-17)21(15-37)25(35)30(3)20(23(33)29-22)14-16-7-5-4-6-8-16/h4-12,19-22,32,37-38H,13-15,28H2,1-3H3,(H,29,33)/t19-,20-,21-,22-/m0/s1 FFEQWDXRKVWQPI-CMOCDZPBSA-N 50038410 4-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-9-benzyl-3-mercaptomethyl-6-(1-mercapto-1-methyl-ethyl)-1-methyl-[1,4,7]triazonane-2,5,8-trione::CHEMBL2370834 Mu-type opioid receptor Cavia cutleri >30000 ChEMBL 10.1021/jm00051a016 10.7270/Q2862FH1 7996550 Mosberg, HI; Omnaas, JR; Lomize, A; Heyl, DL; Nordan, I; Mousigian, C; Davis, P; Porreca, F University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038410 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038410&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73345504 103945784 CHEMBL2370834 ZINC36221982 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50039962 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C63H104N22O12/c1-5-37(4)51(59(96)82-45(20-13-29-75-63(71)72)60(97)85-30-14-21-48(85)58(95)79-42(52(66)89)17-9-10-26-64)84-55(92)44(19-12-28-74-62(69)70)80-54(91)43(18-11-27-73-61(67)68)81-56(93)46(31-36(2)3)83-57(94)47(33-38-15-7-6-8-16-38)78-50(88)35-76-49(87)34-77-53(90)41(65)32-39-22-24-40(86)25-23-39/h6-8,15-16,22-25,36-37,41-48,51,86H,5,9-14,17-21,26-35,64-65H2,1-4H3,(H2,66,89)(H,76,87)(H,77,90)(H,78,88)(H,79,95)(H,80,91)(H,81,93)(H,82,96)(H,83,94)(H,84,92)(H4,67,68,73)(H4,69,70,74)(H4,71,72,75)/t37-,41-,42-,43-,44-,45-,46-,47-,48-,51-/m0/s1 OKJAOUBQLSWUNX-QFIUEGLPSA-N 50033143 CHEMBL216640::H-Tyr-Gly-Gly-Phe-Leu-Arg-Lys-Ile*-Lys*-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln-OH Mu-type opioid receptor Cavia cutleri 9.9 ChEMBL 10.1021/jm00018a006 10.7270/Q2QZ291Q 7658433 Meyer, JP; Davis, P; Lee, KB; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033143&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10677974 103941477 CHEMBL216640 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037862 CN([C@H](CN1CCCC1)c1cccc(N)c1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C21H25Cl2N3O/c1-25(21(27)12-15-7-8-18(22)19(23)11-15)20(14-26-9-2-3-10-26)16-5-4-6-17(24)13-16/h4-8,11,13,20H,2-3,9-10,12,14,24H2,1H3/t20-/m1/s1 GZGGYQMNFMHDFI-HXUWFJFHSA-N 50035476 CHEMBL413530::N-[(S)-1-(3-Amino-phenyl)-2-pyrrolidin-1-yl-ethyl]-2-(3,4-dichloro-phenyl)-N-methyl-acetamide Mu-type opioid receptor Cavia cutleri 31 ChEMBL 10.1021/jm00052a008 10.7270/Q2MW2G5Z 7799399 Chang, AC; Takemori, AE; Ojala, WH; Gleason, WB; Portoghese, PS University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035476 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035476&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10456060 103943493 CHEMBL413530 ZINC00599445 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50037864 CN([C@H](CN1CCCC1)c1cccc(c1)N=C=S)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C22H23Cl2N3OS/c1-26(22(28)12-16-7-8-19(23)20(24)11-16)21(14-27-9-2-3-10-27)17-5-4-6-18(13-17)25-15-29/h4-8,11,13,21H,2-3,9-10,12,14H2,1H3/t21-/m1/s1 BNAKCEFXXMHXDQ-OAQYLSRUSA-N 50035471 2-(3,4-Dichloro-phenyl)-N-[(S)-1-(3-isothiocyanato-phenyl)-2-pyrrolidin-1-yl-ethyl]-N-methyl-acetamide::CHEMBL38521 Mu-type opioid receptor Cavia cutleri 1799 ChEMBL 10.1021/jm00052a008 10.7270/Q2MW2G5Z 7799399 Chang, AC; Takemori, AE; Ojala, WH; Gleason, WB; Portoghese, PS University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035471&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 127914 103943490 CHEMBL38521 ZINC02567731 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041176 NCCC[C@@H](NC(=O)c1cccc2c3C[C@@]4(O)C5Cc6ccc(O)c7O[C@@H](c3[nH]c12)C4(CCN5CC1CC1)c67)C(O)=O InChI=1S/C32H36N4O6/c33-11-2-5-21(30(39)40)34-29(38)19-4-1-3-18-20-14-32(41)23-13-17-8-9-22(37)27-24(17)31(32,10-12-36(23)15-16-6-7-16)28(42-27)26(20)35-25(18)19/h1,3-4,8-9,16,21,23,28,35,37,41H,2,5-7,10-15,33H2,(H,34,38)(H,39,40)/t21-,23?,28+,31?,32-/m1/s1 UTJUZGQNYUMWPT-MZFPFZBHSA-N 50036138 5-amino-2-[22-cyclopropylmethyl-2,16-dihydroxy-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaen-9-ylcarboxamido]-(2R)-pentanoic acid::CHEMBL132897 Mu-type opioid receptor Cavia cutleri 136 ChEMBL 10.1021/jm00003a002 10.7270/Q22N52W5 7853332 Portoghese, PS; Farouz-Grant, F; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036138 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036138&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44353391 103944003 CHEMBL132897 ZINC03918642 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041178 NCCCC[C@@H](NC(=O)c1cccc2c3C[C@@]4(O)C5Cc6ccc(O)c7O[C@@H](c3[nH]c12)C4(CCN5CC1CC1)c67)C(O)=O InChI=1S/C33H38N4O6/c34-12-2-1-6-22(31(40)41)35-30(39)20-5-3-4-19-21-15-33(42)24-14-18-9-10-23(38)28-25(18)32(33,11-13-37(24)16-17-7-8-17)29(43-28)27(21)36-26(19)20/h3-5,9-10,17,22,24,29,36,38,42H,1-2,6-8,11-16,34H2,(H,35,39)(H,40,41)/t22-,24?,29+,32?,33-/m1/s1 XVHSCIPOAOUAJI-RLDRNQAHSA-N 50036136 6-amino-2-[22-cyclopropylmethyl-2,16-dihydroxy-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaen-9-ylcarboxamido]-(2R)-hexanoic acid::CHEMBL335936 Mu-type opioid receptor Cavia cutleri 219 ChEMBL 10.1021/jm00003a002 10.7270/Q22N52W5 7853332 Portoghese, PS; Farouz-Grant, F; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036136&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44353390 103944001 CHEMBL335936 ZINC27332155 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041182 OC(=O)C[C@@H](NC(=O)c1cccc2c3C[C@@]4(O)C5Cc6ccc(O)c7O[C@@H](c3[nH]c12)C4(CCN5CC1CC1)c67)C(O)=O InChI=1S/C31H31N3O8/c35-20-7-6-15-10-21-31(41)12-18-16-2-1-3-17(28(38)32-19(29(39)40)11-22(36)37)24(16)33-25(18)27-30(31,23(15)26(20)42-27)8-9-34(21)13-14-4-5-14/h1-3,6-7,14,19,21,27,33,35,41H,4-5,8-13H2,(H,32,38)(H,36,37)(H,39,40)/t19-,21?,27+,30?,31-/m1/s1 OPMKMCOJTGUVGA-IRECNROUSA-N 50036137 2-[22-cyclopropylmethyl-2,16-dihydroxy-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaen-9-ylcarboxamido]-(2R)-butanedioic acid::CHEMBL334970 Mu-type opioid receptor Cavia cutleri 368 ChEMBL 10.1021/jm00003a002 10.7270/Q22N52W5 7853332 Portoghese, PS; Farouz-Grant, F; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036137 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036137&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44353454 103944002 CHEMBL334970 C06380 ZINC27405877 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041187 Oc1ccc2C[C@H]3N(CC4CC4)CCC45C(Oc1c24)c1[nH]c2ccccc2c1CC35O InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1 WIYUZYBFCWCCQJ-XEWUMVRVSA-N 21864 (21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.0^{1,13}.0^{2,21}.0^{4,12}.0^{5,10}.0^{19,25}]pentacosa-4(12),5,7,9,15,17,19(25)-heptaene-2,16-diol::(8R)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol::NALTRINDOLE::[3H]-naltrindole Mu-type opioid receptor Cavia cutleri 3.8 ChEMBL 10.1021/jm00003a002 10.7270/Q22N52W5 7853332 Portoghese, PS; Farouz-Grant, F; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21864&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3034754 49700969 ZINC62153992 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041194 OC(=O)c1cccc2c3C[C@@]4(O)C5Cc6ccc(O)c7O[C@@H](c3[nH]c12)C4(CCN5CC1CC1)c67 InChI=1S/C27H26N2O5/c30-18-7-6-14-10-19-27(33)11-17-15-2-1-3-16(25(31)32)21(15)28-22(17)24-26(27,20(14)23(18)34-24)8-9-29(19)12-13-4-5-13/h1-3,6-7,13,19,24,28,30,33H,4-5,8-12H2,(H,31,32)/t19?,24-,26?,27+/m0/s1 CSUXYXHTJTUDSO-UIHGGPOCSA-N 50036140 22-cyclopropylmethyl-2,16-dihydroxy-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-9-carboxylic acid::CHEMBL132420 Mu-type opioid receptor Cavia cutleri 24 ChEMBL 10.1021/jm00003a002 10.7270/Q22N52W5 7853332 Portoghese, PS; Farouz-Grant, F; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036140 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036140&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44353468 103944004 CHEMBL132420 ZINC13602313 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041201 NC(=N)NCCC[C@@H](NC(=O)c1cccc2c3C[C@@]4(O)C5Cc6ccc(O)c7O[C@@H](c3[nH]c12)C4(CCN5CC1CC1)c67)C(O)=O InChI=1S/C33H38N6O6/c34-31(35)36-11-2-5-21(30(42)43)37-29(41)19-4-1-3-18-20-14-33(44)23-13-17-8-9-22(40)27-24(17)32(33,10-12-39(23)15-16-6-7-16)28(45-27)26(20)38-25(18)19/h1,3-4,8-9,16,21,23,28,38,40,44H,2,5-7,10-15H2,(H,37,41)(H,42,43)(H4,34,35,36)/t21-,23?,28+,32?,33-/m1/s1 SIUVQQDAATZZEL-YFMZUUBZSA-N 50036135 5-amino(imino)methylamino-2-[22-cyclopropylmethyl-2,16-dihydroxy-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaen-9-ylcarboxamido]-(2R)-pentanoic acid::CHEMBL334715 Mu-type opioid receptor Cavia cutleri 333 ChEMBL 10.1021/jm00003a002 10.7270/Q22N52W5 7853332 Portoghese, PS; Farouz-Grant, F; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036135 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036135&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44353458 103944000 CHEMBL334715 ZINC36221280 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041202 OC(=O)CNC(=O)c1cccc2c3C[C@@]4(O)C5Cc6ccc(O)c7O[C@@H](c3[nH]c12)C4(CCN5CC1CC1)c67 InChI=1S/C29H29N3O6/c33-19-7-6-15-10-20-29(37)11-18-16-2-1-3-17(27(36)30-12-21(34)35)23(16)31-24(18)26-28(29,22(15)25(19)38-26)8-9-32(20)13-14-4-5-14/h1-3,6-7,14,20,26,31,33,37H,4-5,8-13H2,(H,30,36)(H,34,35)/t20?,26-,28?,29+/m0/s1 WOEJGSIUPIRJEQ-PPIWYSOJSA-N 50036134 32+/-82-[22-cyclopropylmethyl-2,16-dihydroxy-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaen-9-ylcarboxamido]acetic acid::CHEMBL422258 Mu-type opioid receptor Cavia cutleri 206 ChEMBL 10.1021/jm00003a002 10.7270/Q22N52W5 7853332 Portoghese, PS; Farouz-Grant, F; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036134 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036134&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44353457 103943999 CHEMBL422258 ZINC03918640 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50042328 CN1CC[C@@]2(C[C@H]1Cc1[nH]c3ccccc3c21)c1cccc(O)c1 InChI=1S/C21H22N2O/c1-23-10-9-21(14-5-4-6-16(24)11-14)13-15(23)12-19-20(21)17-7-2-3-8-18(17)22-19/h2-8,11,15,22,24H,9-10,12-13H2,1H3/t15-,21-/m1/s1 WMJAKEDTFIYKBZ-QVKFZJNVSA-N 50454127 CHEMBL2111529 Mu-type opioid receptor Cavia cutleri 2345 ChEMBL 10.1021/jm950695s 10.7270/Q2FQ9X82 8642567 Bertha, CM; Ellis, M; Flippen-Anderson, JL; Porreca, F; Rothman, RB; Davis, P; Xu, H; Becketts, K; Rice, KC National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50454127 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50454127&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10426038 225146171 CHEMBL2111529 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50042337 CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23-,24-/m0/s1 MCMMCRYPQBNCPH-DVKRWUGUSA-N 50001683 13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid::7-Benzyl-10-{[3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL294616::DPDPE Mu-type opioid receptor Cavia cutleri 7300 ChEMBL 10.1021/jm950695s 10.7270/Q2FQ9X82 8642567 Bertha, CM; Ellis, M; Flippen-Anderson, JL; Porreca, F; Rothman, RB; Davis, P; Xu, H; Becketts, K; Rice, KC National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001683&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299404 103916113 CHEMBL294616 ZINC27520031 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50042356 COc1ccc2[nH]c3CC4CC(CCN4C)(c3c2c1)c1cccc(O)c1 InChI=1S/C22H24N2O2/c1-24-9-8-22(14-4-3-5-16(25)10-14)13-15(24)11-20-21(22)18-12-17(26-2)6-7-19(18)23-20/h3-7,10,12,15,23,25H,8-9,11,13H2,1-2H3 QRSAMOUGQMIXEX-UHFFFAOYSA-N 50050509 (-)3(1,2,3,4,5,11-Hexahydro-3-methyl-2,6-methano-8-methoxy-6H-aocino[4,5-b]indol-6-yl)phenol methanesulfonate::3(1,2,3,4,5,11-Hexahydro-3-methyl-2,6-methano-8-methoxy-6H-aocino[4,5-b]indol-6-yl)phenol methanesulfonate::CHEMBL65348 Mu-type opioid receptor Cavia cutleri 6760 ChEMBL 10.1021/jm950695s 10.7270/Q2FQ9X82 8642567 Bertha, CM; Ellis, M; Flippen-Anderson, JL; Porreca, F; Rothman, RB; Davis, P; Xu, H; Becketts, K; Rice, KC National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050509&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10689084 103947670 CHEMBL65348 ZINC13756000 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50042361 COc1cccc2c3c(CC4CC3(CCN4C)c3cccc(O)c3)[nH]c12 InChI=1S/C22H24N2O2/c1-24-10-9-22(14-5-3-6-16(25)11-14)13-15(24)12-18-20(22)17-7-4-8-19(26-2)21(17)23-18/h3-8,11,15,23,25H,9-10,12-13H2,1-2H3 ZIOKSJYZYLYKRX-UHFFFAOYSA-N 50050507 (-) (2S,6R)-3(1,2,3,4,5,11-Hexahydro-3-methyl-2,6-methano-10-methoxy-6H-azocino[4,5-b]indol-6-yl)phenol methanesulfonate::3(1,2,3,4,5,11-Hexahydro-3-methyl-2,6-methano-10-methoxy-6H-azocino[4,5-b]indol-6-yl)phenol methanesulfonate::CHEMBL302454 Mu-type opioid receptor Cavia cutleri 2890 ChEMBL 10.1021/jm950695s 10.7270/Q2FQ9X82 8642567 Bertha, CM; Ellis, M; Flippen-Anderson, JL; Porreca, F; Rothman, RB; Davis, P; Xu, H; Becketts, K; Rice, KC National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050507 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050507&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10593864 103947668 CHEMBL302454 ZINC13755993 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50042365 CC(C)C[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C29H39N5O7/c1-17(2)13-24(29(40)41)34-28(39)23(15-19-7-5-4-6-8-19)33-25(36)16-31-26(37)18(3)32-27(38)22(30)14-20-9-11-21(35)12-10-20/h4-12,17-18,22-24,35H,13-16,30H2,1-3H3,(H,31,37)(H,32,38)(H,33,36)(H,34,39)(H,40,41)/t18-,22+,23+,24-/m1/s1 ZHUJMSMQIPIPTF-IBURTVSXSA-N 21025 (2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanamido]-4-methylpentanoic acid::(D-Ala2,D-Leu5)-Enkephalin::BW-180C::CHEMBL340032::DADLE::DADLE-OH::H-Tyr-D-Ala-Gly-Phe-D-Leu-OH::[D-Ala2-D-Leu5]enkephalin Mu-type opioid receptor Cavia cutleri 29 ChEMBL 10.1021/jm950695s 10.7270/Q2FQ9X82 8642567 Bertha, CM; Ellis, M; Flippen-Anderson, JL; Porreca, F; Rothman, RB; Davis, P; Xu, H; Becketts, K; Rice, KC National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21025&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 6917707 49689098 CHEMBL340032 ZINC14952092 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041260 Oc1ccc2CC3N(CC4CC4)CCC45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)OCc1ccccc1CN=C=S InChI=1S/C29H32N2O4S/c32-22-8-7-19-13-24-29(33)10-9-23(34-16-21-4-2-1-3-20(21)14-30-17-36)27-28(29,25(19)26(22)35-27)11-12-31(24)15-18-5-6-18/h1-4,7-8,18,23-24,27,32-33H,5-6,9-16H2/t23-,24?,27+,28?,29-/m1/s1 IDVCTKLFKIONIA-ILORQFCNSA-N 50036245 4-cyclopropylmethyl-14-(2-isothiocyanatomethylbenzyloxy)-(1S,13R,14R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-triene-10,17-diol(o-CH2NCS)::CHEMBL152327 Mu-type opioid receptor Cavia cutleri 20 ChEMBL 10.1021/jm00003a020 10.7270/Q2XW4KFB 7853350 Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036245 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036245&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44369609 103944081 CHEMBL152327 ZINC36221378 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041262 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1 DQCKKXVULJGBQN-XFWGSAIBSA-N 60212 (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::MLS000069607::NALTREXONE HYDROCHLORIDE::SMR000058767::US10988481, Compound NTX::US9107954, naltrexone::cid_5485201 Mu-type opioid receptor Cavia cutleri 0.200000 ChEMBL 10.1021/jm00003a020 10.7270/Q2XW4KFB 7853350 Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60212&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5360515 252639834 DB00704 C07253 ZINC00001773 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041332 Oc1ccc2CC3N(CC4CC4)CCC45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)OCc1cccc(c1)N=C=S InChI=1S/C28H30N2O4S/c31-21-7-6-19-13-23-28(32)9-8-22(33-15-18-2-1-3-20(12-18)29-16-35)26-27(28,24(19)25(21)34-26)10-11-30(23)14-17-4-5-17/h1-3,6-7,12,17,22-23,26,31-32H,4-5,8-11,13-15H2/t22-,23?,26+,27?,28-/m1/s1 HUGRODXDKPWVHV-OWGJQLEISA-N 50036242 4-cyclopropylmethyl-14-(3-isothiocyanatobenzyloxy)-(1S,13R,14R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-triene-10,17-diol(m-NCS)::CHEMBL154510 Mu-type opioid receptor Cavia cutleri 27 ChEMBL 10.1021/jm00003a020 10.7270/Q2XW4KFB 7853350 Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036242 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036242&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44369629 103944078 CHEMBL154510 ZINC36221375 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041338 O[C@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45 InChI=1S/C20H25NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,14-15,18,22-24H,1-2,5-10H2/t14-,15+,18-,19-,20+/m0/s1 JLVNEHKORQFVQJ-SBCNTATESA-N 50254511 CHEMBL468469::Naltrexone-6-alpha-ol Mu-type opioid receptor Cavia cutleri 1.1 ChEMBL 10.1021/jm00003a020 10.7270/Q2XW4KFB 7853350 Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50254511 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50254511&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16099582 104106716 CHEMBL468469 ZINC01656961 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041340 Oc1ccc2CC3N(CC4CC4)CCC45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)OCc1ccc(CN=C=S)cc1 InChI=1S/C29H32N2O4S/c32-22-8-7-21-13-24-29(33)10-9-23(34-16-20-5-1-18(2-6-20)14-30-17-36)27-28(29,25(21)26(22)35-27)11-12-31(24)15-19-3-4-19/h1-2,5-8,19,23-24,27,32-33H,3-4,9-16H2/t23-,24?,27+,28?,29-/m1/s1 QYVRXDNHVNNEIV-ILORQFCNSA-N 50036248 4-cyclopropylmethyl-14-(4-isothiocyanatomethylbenzyloxy)-(1S,13R,14R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-triene-10,17-diol(p-CH2NCS)::CHEMBL347674 Mu-type opioid receptor Cavia cutleri 11 ChEMBL 10.1021/jm00003a020 10.7270/Q2XW4KFB 7853350 Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036248 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036248&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44369600 103944084 CHEMBL347674 ZINC36221386 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041343 Oc1ccc2CC3N(CC4CC4)CCC45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)OCc1ccccc1N=C=S InChI=1S/C28H30N2O4S/c31-21-8-7-18-13-23-28(32)10-9-22(33-15-19-3-1-2-4-20(19)29-16-35)26-27(28,24(18)25(21)34-26)11-12-30(23)14-17-5-6-17/h1-4,7-8,17,22-23,26,31-32H,5-6,9-15H2/t22-,23?,26+,27?,28-/m1/s1 ASQKMNDCAVTNOQ-OWGJQLEISA-N 50036249 4-cyclopropylmethyl-14-(2-isothiocyanatobenzyloxy)-(13R,14R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-triene-10,17-diol(o-NCS)::CHEMBL345208 Mu-type opioid receptor Cavia cutleri 0.800000 ChEMBL 10.1021/jm00003a020 10.7270/Q2XW4KFB 7853350 Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036249 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036249&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44369628 103944085 CHEMBL345208 ZINC36221388 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041344 Oc1ccc2CC3N(CC4CC4)CCC45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)OCc1cccc(CN=C=S)c1 InChI=1S/C29H32N2O4S/c32-22-7-6-21-13-24-29(33)9-8-23(34-16-20-3-1-2-19(12-20)14-30-17-36)27-28(29,25(21)26(22)35-27)10-11-31(24)15-18-4-5-18/h1-3,6-7,12,18,23-24,27,32-33H,4-5,8-11,13-16H2/t23-,24?,27+,28?,29-/m1/s1 ZZUMMIIZPPHGNB-ILORQFCNSA-N 50036247 4-cyclopropylmethyl-14-(3-isothiocyanatomethylbenzyloxy)-(1S,13R,14R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-triene-10,17-diol(m-CH2NCS)::CHEMBL152351 Mu-type opioid receptor Cavia cutleri 19 ChEMBL 10.1021/jm00003a020 10.7270/Q2XW4KFB 7853350 Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036247&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44369383 103944083 CHEMBL152351 ZINC36221372 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041347 Oc1ccc2CC3N(CC4CC4)CCC45C(Oc1c24)[C@@H](CCC35O)OCc1ccccc1 InChI=1S/C27H31NO4/c29-20-9-8-19-14-22-27(30)11-10-21(31-16-18-4-2-1-3-5-18)25-26(27,23(19)24(20)32-25)12-13-28(22)15-17-6-7-17/h1-5,8-9,17,21-22,25,29-30H,6-7,10-16H2/t21-,22?,25?,26?,27?/m1/s1 LLYKFTJDMLXUDK-XVMPFKDUSA-N 50453488 CHEMBL2112732 Mu-type opioid receptor Cavia cutleri 2.4 ChEMBL 10.1021/jm00003a020 10.7270/Q2XW4KFB 7853350 Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453488 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453488&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71456227 225145958 CHEMBL2112732 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041348 Oc1ccc2CC3N(CC4CC4)CCC45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)OCc1ccc(cc1)N=C=S InChI=1S/C28H30N2O4S/c31-21-8-5-19-13-23-28(32)10-9-22(33-15-18-3-6-20(7-4-18)29-16-35)26-27(28,24(19)25(21)34-26)11-12-30(23)14-17-1-2-17/h3-8,17,22-23,26,31-32H,1-2,9-15H2/t22-,23?,26+,27?,28-/m1/s1 MQXHRAHADPPNRD-OWGJQLEISA-N 50036244 4-cyclopropylmethyl-14-(4-isothiocyanatobenzyloxy)-(1S,13R,14R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-triene-10,17-diol(p-NCS)::CHEMBL352224 Mu-type opioid receptor Cavia cutleri 9.6 ChEMBL 10.1021/jm00003a020 10.7270/Q2XW4KFB 7853350 Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036244 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036244&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44369365 103944080 CHEMBL352224 ZINC36221381 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041351 CN([C@H]1C[C@@]2(CCCO2)CC[C@@H]1N1CCCC1)C(=O)Cc1ccccc1 InChI=1S/C22H32N2O2/c1-23(21(25)16-18-8-3-2-4-9-18)20-17-22(11-7-15-26-22)12-10-19(20)24-13-5-6-14-24/h2-4,8-9,19-20H,5-7,10-17H2,1H3/t19-,20-,22+/m0/s1 PGJPPWQHDNODBR-JAXLGGSGSA-N 50381677 CHEMBL1256748::U-69593 Mu-type opioid receptor Cavia cutleri 1760 ChEMBL 10.1021/jm00003a020 10.7270/Q2XW4KFB 7853350 Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50381677 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50381677&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 52947240 160860760 CHEMBL1256748 ZINC64539951 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041353 CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23-,24-/m0/s1 MCMMCRYPQBNCPH-DVKRWUGUSA-N 50001683 13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid::7-Benzyl-10-{[3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL294616::DPDPE Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm00003a020 10.7270/Q2XW4KFB 7853350 Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001683&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299404 103916113 CHEMBL294616 ZINC27520031 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041372 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C64H106N22O12/c1-6-37(4)51(60(97)82-46(21-14-30-76-64(72)73)61(98)86-31-15-22-49(86)59(96)79-43(52(67)89)18-10-11-27-65)85-56(93)45(20-13-29-75-63(70)71)80-55(92)44(19-12-28-74-62(68)69)81-57(94)47(32-36(2)3)84-58(95)48(34-39-16-8-7-9-17-39)83-53(90)38(5)78-50(88)35-77-54(91)42(66)33-40-23-25-41(87)26-24-40/h7-9,16-17,23-26,36-38,42-49,51,87H,6,10-15,18-22,27-35,65-66H2,1-5H3,(H2,67,89)(H,77,91)(H,78,88)(H,79,96)(H,80,92)(H,81,94)(H,82,97)(H,83,90)(H,84,95)(H,85,93)(H4,68,69,74)(H4,70,71,75)(H4,72,73,76)/t37-,38-,42-,43-,44-,45-,46-,47-,48-,49-,51-/m0/s1 AQXYHKIZMZEAGF-VJDVOYKLSA-N 50036266 CHEMBL262963::Dyn A(H-Tyr-Gly-Ala-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys)-NH2::Dyn A(H-Tyr-Gly-D-Ala-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys)-NH2::Linear [Ala3]Dyn A-(1-11)NH2 Mu-type opioid receptor Cavia cutleri 210 ChEMBL 10.1021/jm00004a002 10.7270/Q2NP23F7 7861405 Lung, FD; Meyer, JP; Li, G; Lou, BS; Stropova, D; Davis, P; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036266 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036266&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10374265 103944102 CHEMBL262963 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041373 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C64H106N22O12/c1-6-37(4)51(60(97)82-46(21-14-30-76-64(72)73)61(98)86-31-15-22-49(86)59(96)79-43(52(67)89)18-10-11-27-65)85-56(93)45(20-13-29-75-63(70)71)80-55(92)44(19-12-28-74-62(68)69)81-57(94)47(32-36(2)3)84-58(95)48(34-39-16-8-7-9-17-39)83-53(90)38(5)78-50(88)35-77-54(91)42(66)33-40-23-25-41(87)26-24-40/h7-9,16-17,23-26,36-38,42-49,51,87H,6,10-15,18-22,27-35,65-66H2,1-5H3,(H2,67,89)(H,77,91)(H,78,88)(H,79,96)(H,80,92)(H,81,94)(H,82,97)(H,83,90)(H,84,95)(H,85,93)(H4,68,69,74)(H4,70,71,75)(H4,72,73,76)/t37-,38+,42-,43-,44-,45-,46-,47-,48-,49-,51-/m0/s1 AQXYHKIZMZEAGF-DFQGMJKVSA-N 50138774 CHEMBL415795::Linear [D-Ala3]Dyn A-(1-11)NH2 Mu-type opioid receptor Cavia cutleri 260 ChEMBL 10.1021/jm00004a002 10.7270/Q2NP23F7 7861405 Lung, FD; Meyer, JP; Li, G; Lou, BS; Stropova, D; Davis, P; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50138774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50138774&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9989078 104028797 CHEMBL415795 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041375 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(OC)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C64H106N22O12/c1-6-38(4)52(60(96)83-46(21-14-30-76-64(72)73)61(97)86-31-15-22-49(86)59(95)80-43(53(67)89)18-10-11-27-65)85-56(92)45(20-13-29-75-63(70)71)81-55(91)44(19-12-28-74-62(68)69)82-57(93)47(32-37(2)3)84-58(94)48(34-39-16-8-7-9-17-39)79-51(88)36-77-50(87)35-78-54(90)42(66)33-40-23-25-41(98-5)26-24-40/h7-9,16-17,23-26,37-38,42-49,52H,6,10-15,18-22,27-36,65-66H2,1-5H3,(H2,67,89)(H,77,87)(H,78,90)(H,79,88)(H,80,95)(H,81,91)(H,82,93)(H,83,96)(H,84,94)(H,85,92)(H4,68,69,74)(H4,70,71,75)(H4,72,73,76)/t38-,42-,43-,44-,45-,46-,47-,48-,49-,52-/m0/s1 QFVUNUQQZFBNDU-MTGCXMICSA-N 50036267 CHEMBL268874::Dyn A(H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys)-NH2 Mu-type opioid receptor Cavia cutleri 9.9 ChEMBL 10.1021/jm00004a002 10.7270/Q2NP23F7 7861405 Lung, FD; Meyer, JP; Li, G; Lou, BS; Stropova, D; Davis, P; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036267 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036267&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44369919 103944103 CHEMBL268874 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50042653 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)NC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C65H108N22O12/c1-7-38(4)52(61(98)83-47(22-15-31-77-65(73)74-6)62(99)87-32-16-23-50(87)60(97)80-44(53(68)90)19-11-12-28-66)86-57(94)46(21-14-30-76-64(71)72)81-56(93)45(20-13-29-75-63(69)70)82-58(95)48(33-37(2)3)85-59(96)49(35-40-17-9-8-10-18-40)84-54(91)39(5)79-51(89)36-78-55(92)43(67)34-41-24-26-42(88)27-25-41/h8-10,17-18,24-27,37-39,43-50,52,88H,7,11-16,19-23,28-36,66-67H2,1-6H3,(H2,68,90)(H,78,92)(H,79,89)(H,80,97)(H,81,93)(H,82,95)(H,83,98)(H,84,91)(H,85,96)(H,86,94)(H4,69,70,75)(H4,71,72,76)(H3,73,74,77)/t38-,39-,43-,44-,45-,46-,47-,48-,49-,50-,52-/m0/s1 JXBVHXCJLPXFAO-PXTMTJACSA-N 50051594 CHEMBL407303::Dynorphin A analogues Mu-type opioid receptor Cavia cutleri 210 ChEMBL 10.1021/jm950655o 10.7270/Q2C828D7 8691442 Lung, FD; Meyer, JP; Lou, BS; Xiang, L; Li, G; Davis, P; DeLeon, IA; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051594&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44460912 103948589 CHEMBL407303 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50043731 CCCC[C@H](N(C)C(=O)[C@@H](NC(=O)CNC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CC(O)=O)[C@H](C)c1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C56H68N10O13/c1-4-5-20-45(55(78)64-44(29-48(71)72)54(77)61-41(50(58)73)25-33-14-8-6-9-15-33)66(3)56(79)49(32(2)38-30-59-40-19-13-12-18-37(38)40)65-46(68)31-60-52(75)42(26-34-16-10-7-11-17-34)63-53(76)43(27-35-21-23-36(67)24-22-35)62-51(74)39(57)28-47(69)70/h6-19,21-24,30,32,39,41-45,49,59,67H,4-5,20,25-29,31,57H2,1-3H3,(H2,58,73)(H,60,75)(H,61,77)(H,62,74)(H,63,76)(H,64,78)(H,65,68)(H,69,70)(H,71,72)/t32-,39+,41+,42-,43+,44+,45+,49+/m1/s1 LWLWLSWDXYMACR-PAMFSDIKSA-N 50422178 CHEMBL2112688 Mu-type opioid receptor Cavia cutleri 3050 ChEMBL 10.1021/jm960078j 10.7270/Q2P55P5Z 8831778 Boteju, LW; Nikiforovich, GV; Haskell-Luevano, C; Fang, SN; Zalewska, T; Stropova, D; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422178 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422178&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10748691 164151053 CHEMBL2112688 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50043739 CCCC[C@H](N(C)C(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C55H66N10O13/c1-3-4-19-45(54(77)64-43(29-48(70)71)53(76)61-40(49(57)72)24-32-13-7-5-8-14-32)65(2)55(78)44(27-35-30-58-39-18-12-11-17-37(35)39)60-46(67)31-59-51(74)41(25-33-15-9-6-10-16-33)63-52(75)42(26-34-20-22-36(66)23-21-34)62-50(73)38(56)28-47(68)69/h5-18,20-23,30,38,40-45,58,66H,3-4,19,24-29,31,56H2,1-2H3,(H2,57,72)(H,59,74)(H,60,67)(H,61,76)(H,62,73)(H,63,75)(H,64,77)(H,68,69)(H,70,71)/t38-,40-,41+,42-,43-,44-,45-/m0/s1 IJHCWGDIGBABKC-GDHOWUIUSA-N 21146 (3S)-3-[(2S)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-[(3S)-3-amino-3-formamidopropanoic acid]-3-(4-hydroxyphenyl)propanamido]-3-phenylpropanamido]acetamido}-3-(1H-indol-3-yl)-N-methylpropanamido]hexanamido]-3-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}propanoic acid::Asp-Tyr-D-Phe-Gly-Trp-NMeNle-Asp-Phe-NH2::CHEMBL407057::SNF-9007 Mu-type opioid receptor Cavia cutleri 700 ChEMBL 10.1021/jm960078j 10.7270/Q2P55P5Z 8831778 Boteju, LW; Nikiforovich, GV; Haskell-Luevano, C; Fang, SN; Zalewska, T; Stropova, D; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21146 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21146&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9898185 49689219 CHEMBL407057 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50043740 CCCC[C@H](N(C)C(=O)[C@@H](NC(=O)CNC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CC(O)=O)[C@@H](C)c1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C56H68N10O13/c1-4-5-20-45(55(78)64-44(29-48(71)72)54(77)61-41(50(58)73)25-33-14-8-6-9-15-33)66(3)56(79)49(32(2)38-30-59-40-19-13-12-18-37(38)40)65-46(68)31-60-52(75)42(26-34-16-10-7-11-17-34)63-53(76)43(27-35-21-23-36(67)24-22-35)62-51(74)39(57)28-47(69)70/h6-19,21-24,30,32,39,41-45,49,59,67H,4-5,20,25-29,31,57H2,1-3H3,(H2,58,73)(H,60,75)(H,61,77)(H,62,74)(H,63,76)(H,64,78)(H,65,68)(H,69,70)(H,71,72)/t32-,39-,41-,42+,43-,44-,45-,49-/m0/s1 LWLWLSWDXYMACR-DTEDLYEKSA-N 50422175 CHEMBL2112689 Mu-type opioid receptor Cavia cutleri 6800 ChEMBL 10.1021/jm960078j 10.7270/Q2P55P5Z 8831778 Boteju, LW; Nikiforovich, GV; Haskell-Luevano, C; Fang, SN; Zalewska, T; Stropova, D; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422175 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422175&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10843787 164151050 CHEMBL2112689 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50043741 CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23-,24-/m0/s1 MCMMCRYPQBNCPH-DVKRWUGUSA-N 50001683 13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid::7-Benzyl-10-{[3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL294616::DPDPE Mu-type opioid receptor Cavia cutleri 7300 ChEMBL 10.1021/jm960078j 10.7270/Q2P55P5Z 8831778 Boteju, LW; Nikiforovich, GV; Haskell-Luevano, C; Fang, SN; Zalewska, T; Stropova, D; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001683&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299404 103916113 CHEMBL294616 ZINC27520031 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50043743 CCCC[C@H](N(C)C(=O)[C@H](NC(=O)CNC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CC(O)=O)[C@H](C)c1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C56H68N10O13/c1-4-5-20-45(55(78)64-44(29-48(71)72)54(77)61-41(50(58)73)25-33-14-8-6-9-15-33)66(3)56(79)49(32(2)38-30-59-40-19-13-12-18-37(38)40)65-46(68)31-60-52(75)42(26-34-16-10-7-11-17-34)63-53(76)43(27-35-21-23-36(67)24-22-35)62-51(74)39(57)28-47(69)70/h6-19,21-24,30,32,39,41-45,49,59,67H,4-5,20,25-29,31,57H2,1-3H3,(H2,58,73)(H,60,75)(H,61,77)(H,62,74)(H,63,76)(H,64,78)(H,65,68)(H,69,70)(H,71,72)/t32-,39+,41+,42-,43+,44+,45+,49-/m1/s1 LWLWLSWDXYMACR-QBQLWZAUSA-N 50422177 CHEMBL2111881 Mu-type opioid receptor Cavia cutleri >30000 ChEMBL 10.1021/jm960078j 10.7270/Q2P55P5Z 8831778 Boteju, LW; Nikiforovich, GV; Haskell-Luevano, C; Fang, SN; Zalewska, T; Stropova, D; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422177 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422177&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10748690 164151052 CHEMBL2111881 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50043744 CCCC[C@H](N(C)C(=O)[C@H](NC(=O)CNC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CC(O)=O)[C@@H](C)c1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C56H68N10O13/c1-4-5-20-45(55(78)64-44(29-48(71)72)54(77)61-41(50(58)73)25-33-14-8-6-9-15-33)66(3)56(79)49(32(2)38-30-59-40-19-13-12-18-37(38)40)65-46(68)31-60-52(75)42(26-34-16-10-7-11-17-34)63-53(76)43(27-35-21-23-36(67)24-22-35)62-51(74)39(57)28-47(69)70/h6-19,21-24,30,32,39,41-45,49,59,67H,4-5,20,25-29,31,57H2,1-3H3,(H2,58,73)(H,60,75)(H,61,77)(H,62,74)(H,63,76)(H,64,78)(H,65,68)(H,69,70)(H,71,72)/t32-,39-,41-,42+,43-,44-,45-,49+/m0/s1 LWLWLSWDXYMACR-ABHUVUBFSA-N 50422176 CHEMBL2111882 Mu-type opioid receptor Cavia cutleri >30000 ChEMBL 10.1021/jm960078j 10.7270/Q2P55P5Z 8831778 Boteju, LW; Nikiforovich, GV; Haskell-Luevano, C; Fang, SN; Zalewska, T; Stropova, D; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422176&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10843788 164151051 CHEMBL2111882 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50042656 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)NC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C65H108N22O12/c1-7-38(4)52(61(98)83-47(22-15-31-77-65(73)74-6)62(99)87-32-16-23-50(87)60(97)80-44(53(68)90)19-11-12-28-66)86-57(94)46(21-14-30-76-64(71)72)81-56(93)45(20-13-29-75-63(69)70)82-58(95)48(33-37(2)3)85-59(96)49(35-40-17-9-8-10-18-40)84-54(91)39(5)79-51(89)36-78-55(92)43(67)34-41-24-26-42(88)27-25-41/h8-10,17-18,24-27,37-39,43-50,52,88H,7,11-16,19-23,28-36,66-67H2,1-6H3,(H2,68,90)(H,78,92)(H,79,89)(H,80,97)(H,81,93)(H,82,95)(H,83,98)(H,84,91)(H,85,96)(H,86,94)(H4,69,70,75)(H4,71,72,76)(H3,73,74,77)/t38-,39+,43-,44-,45-,46-,47-,48-,49-,50-,52-/m0/s1 JXBVHXCJLPXFAO-SAIGEHQASA-N 50051599 CHEMBL415224::Dynorphin A analogues Mu-type opioid receptor Cavia cutleri 260 ChEMBL 10.1021/jm950655o 10.7270/Q2C828D7 8691442 Lung, FD; Meyer, JP; Lou, BS; Xiang, L; Li, G; Davis, P; DeLeon, IA; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051599 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051599&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44460913 103948594 CHEMBL415224 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50042657 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C70H110N22O12/c1-5-42(4)57(66(103)88-51(25-16-34-82-70(78)79)67(104)92-35-17-26-55(92)65(102)85-48(58(73)95)22-12-13-31-71)91-61(98)50(24-15-33-81-69(76)77)86-60(97)49(23-14-32-80-68(74)75)87-62(99)52(36-41(2)3)89-64(101)54(39-44-20-10-7-11-21-44)90-63(100)53(38-43-18-8-6-9-19-43)84-56(94)40-83-59(96)47(72)37-45-27-29-46(93)30-28-45/h6-11,18-21,27-30,41-42,47-55,57,93H,5,12-17,22-26,31-40,71-72H2,1-4H3,(H2,73,95)(H,83,96)(H,84,94)(H,85,102)(H,86,97)(H,87,99)(H,88,103)(H,89,101)(H,90,100)(H,91,98)(H4,74,75,80)(H4,76,77,81)(H4,78,79,82)/t42-,47-,48-,49-,50-,51-,52-,53-,54-,55-,57-/m0/s1 SUPKCEIYQPWSIT-CDKNDKCCSA-N 50051595 CHEMBL413228::Dynorphin A analogues Mu-type opioid receptor Cavia cutleri 27 ChEMBL 10.1021/jm950655o 10.7270/Q2C828D7 8691442 Lung, FD; Meyer, JP; Lou, BS; Xiang, L; Li, G; Davis, P; DeLeon, IA; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051595 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051595&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25092439 103948590 CHEMBL413228 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50042658 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C67H113N23O12/c1-5-40(4)54(63(101)86-49(23-15-33-80-67(76)77)64(102)90-34-16-24-52(90)62(100)83-45(55(71)93)19-9-11-29-68)89-59(97)48(22-14-32-79-66(74)75)84-58(96)47(21-13-31-78-65(72)73)85-60(98)50(35-39(2)3)87-61(99)51(37-41-17-7-6-8-18-41)88-57(95)46(20-10-12-30-69)82-53(92)38-81-56(94)44(70)36-42-25-27-43(91)28-26-42/h6-8,17-18,25-28,39-40,44-52,54,91H,5,9-16,19-24,29-38,68-70H2,1-4H3,(H2,71,93)(H,81,94)(H,82,92)(H,83,100)(H,84,96)(H,85,98)(H,86,101)(H,87,99)(H,88,95)(H,89,97)(H4,72,73,78)(H4,74,75,79)(H4,76,77,80)/t40-,44-,45-,46-,47-,48-,49-,50-,51-,52-,54-/m0/s1 KVDBGDCILMZLFK-XCHTUQNGSA-N 50051604 CHEMBL2369891::Dynorphin A analogues Mu-type opioid receptor Cavia cutleri 7400 ChEMBL 10.1021/jm950655o 10.7270/Q2C828D7 8691442 Lung, FD; Meyer, JP; Lou, BS; Xiang, L; Li, G; Davis, P; DeLeon, IA; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051604 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051604&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10772823 103948599 CHEMBL2369891 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50042661 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C70H110N22O13/c1-5-41(4)57(66(104)88-51(20-13-33-82-70(78)79)67(105)92-34-14-21-55(92)65(103)85-48(58(73)96)17-9-10-30-71)91-61(99)50(19-12-32-81-69(76)77)86-60(98)49(18-11-31-80-68(74)75)87-62(100)52(35-40(2)3)89-64(102)54(37-42-15-7-6-8-16-42)90-63(101)53(38-44-24-28-46(94)29-25-44)84-56(95)39-83-59(97)47(72)36-43-22-26-45(93)27-23-43/h6-8,15-16,22-29,40-41,47-55,57,93-94H,5,9-14,17-21,30-39,71-72H2,1-4H3,(H2,73,96)(H,83,97)(H,84,95)(H,85,103)(H,86,98)(H,87,100)(H,88,104)(H,89,102)(H,90,101)(H,91,99)(H4,74,75,80)(H4,76,77,81)(H4,78,79,82)/t41-,47-,48-,49-,50-,51-,52-,53-,54-,55-,57-/m0/s1 GUZXRROFPXJDPK-QIPSCPOUSA-N 50454203 CHEMBL2369896 Mu-type opioid receptor Cavia cutleri 290 ChEMBL 10.1021/jm950655o 10.7270/Q2C828D7 8691442 Lung, FD; Meyer, JP; Lou, BS; Xiang, L; Li, G; Davis, P; DeLeon, IA; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50454203 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50454203&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25079903 225146179 CHEMBL2369896 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50042663 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C70H110N22O12/c1-5-42(4)57(66(103)88-51(25-16-34-82-70(78)79)67(104)92-35-17-26-55(92)65(102)85-48(58(73)95)22-12-13-31-71)91-61(98)50(24-15-33-81-69(76)77)86-60(97)49(23-14-32-80-68(74)75)87-62(99)52(36-41(2)3)89-64(101)54(39-44-20-10-7-11-21-44)90-63(100)53(38-43-18-8-6-9-19-43)84-56(94)40-83-59(96)47(72)37-45-27-29-46(93)30-28-45/h6-11,18-21,27-30,41-42,47-55,57,93H,5,12-17,22-26,31-40,71-72H2,1-4H3,(H2,73,95)(H,83,96)(H,84,94)(H,85,102)(H,86,97)(H,87,99)(H,88,103)(H,89,101)(H,90,100)(H,91,98)(H4,74,75,80)(H4,76,77,81)(H4,78,79,82)/t42-,47-,48-,49-,50-,51-,52-,53+,54-,55-,57-/m0/s1 SUPKCEIYQPWSIT-XNKRCNKPSA-N 50051603 CHEMBL412792::Dynorphin A analogues Mu-type opioid receptor Cavia cutleri 86 ChEMBL 10.1021/jm950655o 10.7270/Q2C828D7 8691442 Lung, FD; Meyer, JP; Lou, BS; Xiang, L; Li, G; Davis, P; DeLeon, IA; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051603 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051603&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25089498 103948598 CHEMBL412792 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50042665 CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C67H112N22O12/c1-7-39(5)53(87-52(91)37-80-56(93)44(69)35-42-25-27-43(90)28-26-42)62(99)86-50(36-41-18-10-9-11-19-41)60(97)85-49(34-38(3)4)59(96)83-46(21-14-30-77-65(71)72)57(94)82-47(22-15-31-78-66(73)74)58(95)88-54(40(6)8-2)63(100)84-48(23-16-32-79-67(75)76)64(101)89-33-17-24-51(89)61(98)81-45(55(70)92)20-12-13-29-68/h9-11,18-19,25-28,38-40,44-51,53-54,90H,7-8,12-17,20-24,29-37,68-69H2,1-6H3,(H2,70,92)(H,80,93)(H,81,98)(H,82,94)(H,83,96)(H,84,100)(H,85,97)(H,86,99)(H,87,91)(H,88,95)(H4,71,72,77)(H4,73,74,78)(H4,75,76,79)/t39-,40-,44-,45-,46-,47-,48-,49-,50-,51-,53-,54-/m0/s1 UHFZIARRBCSJFR-SYRKVNKJSA-N 50051601 CHEMBL439898::Dynorphin A analogues Mu-type opioid receptor Cavia cutleri 860 ChEMBL 10.1021/jm950655o 10.7270/Q2C828D7 8691442 Lung, FD; Meyer, JP; Lou, BS; Xiang, L; Li, G; Davis, P; DeLeon, IA; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051601&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10510670 103948596 CHEMBL439898 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50042667 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C70H110N22O13/c1-5-41(4)57(66(104)88-51(20-13-33-82-70(78)79)67(105)92-34-14-21-55(92)65(103)85-48(58(73)96)17-9-10-30-71)91-61(99)50(19-12-32-81-69(76)77)86-60(98)49(18-11-31-80-68(74)75)87-62(100)52(35-40(2)3)89-64(102)54(37-42-15-7-6-8-16-42)90-63(101)53(38-44-24-28-46(94)29-25-44)84-56(95)39-83-59(97)47(72)36-43-22-26-45(93)27-23-43/h6-8,15-16,22-29,40-41,47-55,57,93-94H,5,9-14,17-21,30-39,71-72H2,1-4H3,(H2,73,96)(H,83,97)(H,84,95)(H,85,103)(H,86,98)(H,87,100)(H,88,104)(H,89,102)(H,90,101)(H,91,99)(H4,74,75,80)(H4,76,77,81)(H4,78,79,82)/t41-,47-,48-,49-,50-,51-,52-,53+,54-,55-,57-/m0/s1 GUZXRROFPXJDPK-JCCPNRRDSA-N 50051593 CHEMBL438034::Dynorphin A analogues Mu-type opioid receptor Cavia cutleri 650 ChEMBL 10.1021/jm950655o 10.7270/Q2C828D7 8691442 Lung, FD; Meyer, JP; Lou, BS; Xiang, L; Li, G; Davis, P; DeLeon, IA; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051593&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25079902 103948588 CHEMBL438034 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50042671 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C63H104N22O12/c1-5-37(4)51(59(96)82-45(20-13-29-75-63(71)72)60(97)85-30-14-21-48(85)58(95)79-42(52(66)89)17-9-10-26-64)84-55(92)44(19-12-28-74-62(69)70)80-54(91)43(18-11-27-73-61(67)68)81-56(93)46(31-36(2)3)83-57(94)47(33-38-15-7-6-8-16-38)78-50(88)35-76-49(87)34-77-53(90)41(65)32-39-22-24-40(86)25-23-39/h6-8,15-16,22-25,36-37,41-48,51,86H,5,9-14,17-21,26-35,64-65H2,1-4H3,(H2,66,89)(H,76,87)(H,77,90)(H,78,88)(H,79,95)(H,80,91)(H,81,93)(H,82,96)(H,83,94)(H,84,92)(H4,67,68,73)(H4,69,70,74)(H4,71,72,75)/t37-,41-,42-,43-,44-,45-,46-,47-,48-,51-/m0/s1 OKJAOUBQLSWUNX-QFIUEGLPSA-N 50010704 CHEMBL216640::Dyn A(1-11)-NH2::Dynorphin A analogues::H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-NH2::HTyr-Gly-Gly-Phe-Leu-Arg-Arg-lle-Arg-Pro-LysNH2::Linear Dyn A-(1-11)NH2::Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-D-Lys-NH2::Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln-NH2 Mu-type opioid receptor Cavia cutleri 9.9 ChEMBL 10.1021/jm950655o 10.7270/Q2C828D7 8691442 Lung, FD; Meyer, JP; Lou, BS; Xiang, L; Li, G; Davis, P; DeLeon, IA; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010704 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010704&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10677974 103923450 CHEMBL216640 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50042672 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)[C@@H](C)c1c(C)cccc1C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C73H116N22O12/c1-8-42(4)59(68(105)90-53(26-17-35-85-73(81)82)70(107)95-36-18-27-56(95)67(104)87-50(61(76)98)23-12-13-32-74)94-64(101)52(25-16-34-84-72(79)80)88-63(100)51(24-15-33-83-71(77)78)89-65(102)54(37-41(2)3)91-66(103)55(39-46-21-10-9-11-22-46)92-69(106)60(45(7)58-43(5)19-14-20-44(58)6)93-57(97)40-86-62(99)49(75)38-47-28-30-48(96)31-29-47/h9-11,14,19-22,28-31,41-42,45,49-56,59-60,96H,8,12-13,15-18,23-27,32-40,74-75H2,1-7H3,(H2,76,98)(H,86,99)(H,87,104)(H,88,100)(H,89,102)(H,90,105)(H,91,103)(H,92,106)(H,93,97)(H,94,101)(H4,77,78,83)(H4,79,80,84)(H4,81,82,85)/t42-,45-,49-,50-,51-,52-,53-,54-,55-,56-,59-,60+/m0/s1 XMCRIXOSMMNNPQ-CPJNRVENSA-N 50051596 CHEMBL2369903::[(2S,3R)-beta-Me-2',6'-Me2-Phe3] Dynorphin A analogues::[(2S,3S)-beta-Me-2',6'-Me2-Phe3] Dynorphin A analogues Mu-type opioid receptor Cavia cutleri 2350 ChEMBL 10.1021/jm950655o 10.7270/Q2C828D7 8691442 Lung, FD; Meyer, JP; Lou, BS; Xiang, L; Li, G; Davis, P; DeLeon, IA; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051596 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051596&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73350027 103948591 CHEMBL2369903 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50042674 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)[C@@H](C)c1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C71H112N22O12/c1-6-42(4)57(66(103)88-52(26-17-35-83-71(79)80)68(105)93-36-18-27-55(93)65(102)85-49(59(74)96)23-13-14-32-72)92-62(99)51(25-16-34-82-70(77)78)86-61(98)50(24-15-33-81-69(75)76)87-63(100)53(37-41(2)3)89-64(101)54(39-44-19-9-7-10-20-44)90-67(104)58(43(5)46-21-11-8-12-22-46)91-56(95)40-84-60(97)48(73)38-45-28-30-47(94)31-29-45/h7-12,19-22,28-31,41-43,48-55,57-58,94H,6,13-18,23-27,32-40,72-73H2,1-5H3,(H2,74,96)(H,84,97)(H,85,102)(H,86,98)(H,87,100)(H,88,103)(H,89,101)(H,90,104)(H,91,95)(H,92,99)(H4,75,76,81)(H4,77,78,82)(H4,79,80,83)/t42-,43-,48-,49-,50-,51-,52-,53-,54-,55-,57-,58+/m0/s1 LLLZIUPVYZVZTF-PUEAZXOZSA-N 50051592 CHEMBL2369902::[(2S,3R)-beta-MePhe3] Dynorphin A analogues::[(2S,3S)-beta-MePhe3] Dynorphin A analogues Mu-type opioid receptor Cavia cutleri 112 ChEMBL 10.1021/jm950655o 10.7270/Q2C828D7 8691442 Lung, FD; Meyer, JP; Lou, BS; Xiang, L; Li, G; Davis, P; DeLeon, IA; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051592 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051592&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73350026 103948587 CHEMBL2369902 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50042675 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C66H108N22O14/c1-5-38(4)53(62(101)84-47(20-13-31-78-66(74)75)63(102)88-32-14-21-50(88)61(100)81-43(54(69)93)17-9-10-28-67)87-58(97)45(19-12-30-77-65(72)73)82-56(95)44(18-11-29-76-64(70)71)83-59(98)48(33-37(2)3)85-60(99)49(35-39-15-7-6-8-16-39)86-57(96)46(26-27-52(91)92)80-51(90)36-79-55(94)42(68)34-40-22-24-41(89)25-23-40/h6-8,15-16,22-25,37-38,42-50,53,89H,5,9-14,17-21,26-36,67-68H2,1-4H3,(H2,69,93)(H,79,94)(H,80,90)(H,81,100)(H,82,95)(H,83,98)(H,84,101)(H,85,99)(H,86,96)(H,87,97)(H,91,92)(H4,70,71,76)(H4,72,73,77)(H4,74,75,78)/t38-,42-,43-,44-,45-,46-,47-,48-,49-,50-,53-/m0/s1 WAQSKPSRNCKKCL-JPAJDHFGSA-N 50051606 CHEMBL2369901::Dynorphin A analogues Mu-type opioid receptor Cavia cutleri 6600 ChEMBL 10.1021/jm950655o 10.7270/Q2C828D7 8691442 Lung, FD; Meyer, JP; Lou, BS; Xiang, L; Li, G; Davis, P; DeLeon, IA; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051606 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051606&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25087464 103948601 CHEMBL2369901 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50042676 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C67H113N25O12/c1-5-39(4)53(62(103)88-48(22-14-32-82-67(77)78)63(104)92-33-15-23-51(92)61(102)85-44(54(70)95)18-9-10-28-68)91-58(99)47(21-13-31-81-66(75)76)86-57(98)46(20-12-30-80-65(73)74)87-59(100)49(34-38(2)3)89-60(101)50(36-40-16-7-6-8-17-40)90-56(97)45(19-11-29-79-64(71)72)84-52(94)37-83-55(96)43(69)35-41-24-26-42(93)27-25-41/h6-8,16-17,24-27,38-39,43-51,53,93H,5,9-15,18-23,28-37,68-69H2,1-4H3,(H2,70,95)(H,83,96)(H,84,94)(H,85,102)(H,86,98)(H,87,100)(H,88,103)(H,89,101)(H,90,97)(H,91,99)(H4,71,72,79)(H4,73,74,80)(H4,75,76,81)(H4,77,78,82)/t39-,43-,44-,45+,46-,47-,48-,49-,50-,51-,53-/m0/s1 VORCMPXWODNVBK-USWYQPAPSA-N 50051597 CHEMBL269119::Dynorphin A analogues Mu-type opioid receptor Cavia cutleri 5100 ChEMBL 10.1021/jm950655o 10.7270/Q2C828D7 8691442 Lung, FD; Meyer, JP; Lou, BS; Xiang, L; Li, G; Davis, P; DeLeon, IA; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051597 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051597&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25092442 103948592 CHEMBL269119 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50042677 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C66H108N22O14/c1-5-38(4)53(62(101)84-47(20-13-31-78-66(74)75)63(102)88-32-14-21-50(88)61(100)81-43(54(69)93)17-9-10-28-67)87-58(97)45(19-12-30-77-65(72)73)82-56(95)44(18-11-29-76-64(70)71)83-59(98)48(33-37(2)3)85-60(99)49(35-39-15-7-6-8-16-39)86-57(96)46(26-27-52(91)92)80-51(90)36-79-55(94)42(68)34-40-22-24-41(89)25-23-40/h6-8,15-16,22-25,37-38,42-50,53,89H,5,9-14,17-21,26-36,67-68H2,1-4H3,(H2,69,93)(H,79,94)(H,80,90)(H,81,100)(H,82,95)(H,83,98)(H,84,101)(H,85,99)(H,86,96)(H,87,97)(H,91,92)(H4,70,71,76)(H4,72,73,77)(H4,74,75,78)/t38-,42-,43-,44-,45-,46+,47-,48-,49-,50-,53-/m0/s1 WAQSKPSRNCKKCL-AVQQMTKPSA-N 50051605 CHEMBL414554::Dynorphin A analogues Mu-type opioid receptor Cavia cutleri 2500 ChEMBL 10.1021/jm950655o 10.7270/Q2C828D7 8691442 Lung, FD; Meyer, JP; Lou, BS; Xiang, L; Li, G; Davis, P; DeLeon, IA; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051605 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051605&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25085948 103948600 CHEMBL414554 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50042680 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)[C@@H](C)c1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C71H112N22O12/c1-6-42(4)57(66(103)88-52(26-17-35-83-71(79)80)68(105)93-36-18-27-55(93)65(102)85-49(59(74)96)23-13-14-32-72)92-62(99)51(25-16-34-82-70(77)78)86-61(98)50(24-15-33-81-69(75)76)87-63(100)53(37-41(2)3)89-64(101)54(39-44-19-9-7-10-20-44)90-67(104)58(43(5)46-21-11-8-12-22-46)91-56(95)40-84-60(97)48(73)38-45-28-30-47(94)31-29-45/h7-12,19-22,28-31,41-43,48-55,57-58,94H,6,13-18,23-27,32-40,72-73H2,1-5H3,(H2,74,96)(H,84,97)(H,85,102)(H,86,98)(H,87,100)(H,88,103)(H,89,101)(H,90,104)(H,91,95)(H,92,99)(H4,75,76,81)(H4,77,78,82)(H4,79,80,83)/t42-,43-,48-,49-,50-,51-,52-,53-,54-,55-,57-,58-/m0/s1 LLLZIUPVYZVZTF-ZJFVAYEISA-N 50051598 CHEMBL2369124::Dynorphin A analogues Mu-type opioid receptor Cavia cutleri 1350 ChEMBL 10.1021/jm950655o 10.7270/Q2C828D7 8691442 Lung, FD; Meyer, JP; Lou, BS; Xiang, L; Li, G; Davis, P; DeLeon, IA; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051598 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051598&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25083381 103948593 CHEMBL2369124 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50042683 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)[C@@H](C)c1c(C)cccc1C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C73H116N22O12/c1-8-42(4)59(68(105)90-53(26-17-35-85-73(81)82)70(107)95-36-18-27-56(95)67(104)87-50(61(76)98)23-12-13-32-74)94-64(101)52(25-16-34-84-72(79)80)88-63(100)51(24-15-33-83-71(77)78)89-65(102)54(37-41(2)3)91-66(103)55(39-46-21-10-9-11-22-46)92-69(106)60(45(7)58-43(5)19-14-20-44(58)6)93-57(97)40-86-62(99)49(75)38-47-28-30-48(96)31-29-47/h9-11,14,19-22,28-31,41-42,45,49-56,59-60,96H,8,12-13,15-18,23-27,32-40,74-75H2,1-7H3,(H2,76,98)(H,86,99)(H,87,104)(H,88,100)(H,89,102)(H,90,105)(H,91,103)(H,92,106)(H,93,97)(H,94,101)(H4,77,78,83)(H4,79,80,84)(H4,81,82,85)/t42-,45-,49-,50-,51-,52-,53-,54-,55-,56-,59-,60-/m0/s1 XMCRIXOSMMNNPQ-LPUCCUGCSA-N 50051600 CHEMBL2369125::Dynorphin A analogues Mu-type opioid receptor Cavia cutleri 2800 ChEMBL 10.1021/jm950655o 10.7270/Q2C828D7 8691442 Lung, FD; Meyer, JP; Lou, BS; Xiang, L; Li, G; Davis, P; DeLeon, IA; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051600 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051600&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25087470 103948595 CHEMBL2369125 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50042684 CC[C@@H](C)[C@@H](NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C67H112N22O12/c1-7-39(5)53(87-52(91)37-80-56(93)44(69)35-42-25-27-43(90)28-26-42)62(99)86-50(36-41-18-10-9-11-19-41)60(97)85-49(34-38(3)4)59(96)83-46(21-14-30-77-65(71)72)57(94)82-47(22-15-31-78-66(73)74)58(95)88-54(40(6)8-2)63(100)84-48(23-16-32-79-67(75)76)64(101)89-33-17-24-51(89)61(98)81-45(55(70)92)20-12-13-29-68/h9-11,18-19,25-28,38-40,44-51,53-54,90H,7-8,12-17,20-24,29-37,68-69H2,1-6H3,(H2,70,92)(H,80,93)(H,81,98)(H,82,94)(H,83,96)(H,84,100)(H,85,97)(H,86,99)(H,87,91)(H,88,95)(H4,71,72,77)(H4,73,74,78)(H4,75,76,79)/t39-,40+,44+,45+,46+,47+,48+,49+,50+,51+,53-,54+/m1/s1 UHFZIARRBCSJFR-WSMUTZFSSA-N 50454202 CHEMBL2369126 Mu-type opioid receptor Cavia cutleri 1030 ChEMBL 10.1021/jm950655o 10.7270/Q2C828D7 8691442 Lung, FD; Meyer, JP; Lou, BS; Xiang, L; Li, G; Davis, P; DeLeon, IA; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50454202 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50454202&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73351470 225146178 CHEMBL2369126 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50042685 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CCCCN)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C67H113N23O12/c1-5-40(4)54(63(101)86-49(23-15-33-80-67(76)77)64(102)90-34-16-24-52(90)62(100)83-45(55(71)93)19-9-11-29-68)89-59(97)48(22-14-32-79-66(74)75)84-58(96)47(21-13-31-78-65(72)73)85-60(98)50(35-39(2)3)87-61(99)51(37-41-17-7-6-8-18-41)88-57(95)46(20-10-12-30-69)82-53(92)38-81-56(94)44(70)36-42-25-27-43(91)28-26-42/h6-8,17-18,25-28,39-40,44-52,54,91H,5,9-16,19-24,29-38,68-70H2,1-4H3,(H2,71,93)(H,81,94)(H,82,92)(H,83,100)(H,84,96)(H,85,98)(H,86,101)(H,87,99)(H,88,95)(H,89,97)(H4,72,73,78)(H4,74,75,79)(H4,76,77,80)/t40-,44-,45-,46+,47-,48-,49-,50-,51-,52-,54-/m0/s1 KVDBGDCILMZLFK-FVTGJFDSSA-N 50051602 CHEMBL216940::Dynorphin A analogues Mu-type opioid receptor Cavia cutleri 1900 ChEMBL 10.1021/jm950655o 10.7270/Q2C828D7 8691442 Lung, FD; Meyer, JP; Lou, BS; Xiang, L; Li, G; Davis, P; DeLeon, IA; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051602 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051602&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10749029 103948597 CHEMBL216940 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041644 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1cccs1)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C35H50N8O10S/c1-17(2)28(34(52)38-16-26(37)45)43-35(53)29(18(3)4)42-33(51)25(15-27(46)47)41-32(50)24(14-22-7-6-12-54-22)40-30(48)19(5)39-31(49)23(36)13-20-8-10-21(44)11-9-20/h6-12,17-19,23-25,28-29,44H,13-16,36H2,1-5H3,(H2,37,45)(H,38,52)(H,39,49)(H,40,48)(H,41,50)(H,42,51)(H,43,53)(H,46,47)/t19-,23-,24-,25-,28-,29-/m0/s1 SNPUAPGFHRJGOV-UAKCFMCSSA-N 50034247 (S)-3-((S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-thiophen-2-yl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL21361 Mu-type opioid receptor Cavia cutleri 419 ChEMBL 10.1021/jm00007a020 10.7270/Q21835J2 7707326 Heyl, DL; Dandabathula, M; Kurtz, KR; Mousigian, C Eastern Michigan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034247&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44274615 103942451 CHEMBL21361 ZINC95607089 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041645 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C37H52N8O10/c1-19(2)30(36(54)40-18-28(39)47)45-37(55)31(20(3)4)44-35(53)27(17-29(48)49)43-34(52)26(16-22-9-7-6-8-10-22)42-32(50)21(5)41-33(51)25(38)15-23-11-13-24(46)14-12-23/h6-14,19-21,25-27,30-31,46H,15-18,38H2,1-5H3,(H2,39,47)(H,40,54)(H,41,51)(H,42,50)(H,43,52)(H,44,53)(H,45,55)(H,48,49)/t21-,25+,26+,27+,30+,31+/m1/s1 CJAORFIPPWIGPG-QXYJMILXSA-N 50001468 (S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::3-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL317956::H-Tyr-D-Ala-Phe-Asp-Val-Val-Gly-NH2::deltorphin C Mu-type opioid receptor Cavia cutleri 677 ChEMBL 10.1021/jm00007a020 10.7270/Q21835J2 7707326 Heyl, DL; Dandabathula, M; Kurtz, KR; Mousigian, C Eastern Michigan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001468&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10055958 103915933 CHEMBL317956 C18097 ZINC95610551 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041646 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccn1)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C36H51N9O10/c1-18(2)29(35(54)40-17-27(38)47)45-36(55)30(19(3)4)44-34(53)26(16-28(48)49)43-33(52)25(15-22-8-6-7-13-39-22)42-31(50)20(5)41-32(51)24(37)14-21-9-11-23(46)12-10-21/h6-13,18-20,24-26,29-30,46H,14-17,37H2,1-5H3,(H2,38,47)(H,40,54)(H,41,51)(H,42,50)(H,43,52)(H,44,53)(H,45,55)(H,48,49)/t20-,24-,25-,26-,29-,30-/m0/s1 NKYZCEZHCWDFSL-QCYKOXEBSA-N 50034248 (S)-3-((S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-pyridin-2-yl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL21603 Mu-type opioid receptor Cavia cutleri 2930 ChEMBL 10.1021/jm00007a020 10.7270/Q21835J2 7707326 Heyl, DL; Dandabathula, M; Kurtz, KR; Mousigian, C Eastern Michigan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034248 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034248&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44274614 103942452 CHEMBL21603 ZINC95607096 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041648 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccc(C)cc1)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C38H54N8O10/c1-19(2)31(37(55)41-18-29(40)48)46-38(56)32(20(3)4)45-36(54)28(17-30(49)50)44-35(53)27(16-24-9-7-21(5)8-10-24)43-33(51)22(6)42-34(52)26(39)15-23-11-13-25(47)14-12-23/h7-14,19-20,22,26-28,31-32,47H,15-18,39H2,1-6H3,(H2,40,48)(H,41,55)(H,42,52)(H,43,51)(H,44,53)(H,45,54)(H,46,56)(H,49,50)/t22-,26-,27-,28-,31-,32-/m0/s1 ZHROATGUFVHNPC-LJXGPVSSSA-N 50034249 (S)-3-((S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-p-tolyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL21623 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm00007a020 10.7270/Q21835J2 7707326 Heyl, DL; Dandabathula, M; Kurtz, KR; Mousigian, C Eastern Michigan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034249 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034249&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44457580 103942453 CHEMBL21623 ZINC95541746 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041651 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1c(F)c(F)c(F)c(F)c1F)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C37H47F5N8O10/c1-14(2)30(36(59)45-13-23(44)52)50-37(60)31(15(3)4)49-35(58)22(12-24(53)54)48-34(57)21(11-19-25(38)27(40)29(42)28(41)26(19)39)47-32(55)16(5)46-33(56)20(43)10-17-6-8-18(51)9-7-17/h6-9,14-16,20-22,30-31,51H,10-13,43H2,1-5H3,(H2,44,52)(H,45,59)(H,46,56)(H,47,55)(H,48,57)(H,49,58)(H,50,60)(H,53,54)/t16-,20-,21-,22-,30-,31-/m0/s1 ZFSHMYPYENGXAG-PMYVZMRKSA-N 50034244 (S)-3-((S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-pentafluorophenyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL21893 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm00007a020 10.7270/Q21835J2 7707326 Heyl, DL; Dandabathula, M; Kurtz, KR; Mousigian, C Eastern Michigan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034244 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034244&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44274481 103942448 CHEMBL21893 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041653 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1cccc(F)c1)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C37H51FN8O10/c1-18(2)30(36(55)41-17-28(40)48)46-37(56)31(19(3)4)45-35(54)27(16-29(49)50)44-34(53)26(15-22-7-6-8-23(38)13-22)43-32(51)20(5)42-33(52)25(39)14-21-9-11-24(47)12-10-21/h6-13,18-20,25-27,30-31,47H,14-17,39H2,1-5H3,(H2,40,48)(H,41,55)(H,42,52)(H,43,51)(H,44,53)(H,45,54)(H,46,56)(H,49,50)/t20-,25-,26-,27-,30-,31-/m0/s1 YSZYFTORTNQDNC-NKSUJDJASA-N 50034241 (S)-3-[(S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-(3-fluoro-phenyl)-propionylamino]-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL279430 Mu-type opioid receptor Cavia cutleri 3480 ChEMBL 10.1021/jm00007a020 10.7270/Q21835J2 7707326 Heyl, DL; Dandabathula, M; Kurtz, KR; Mousigian, C Eastern Michigan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034241 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034241&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44274482 103942445 CHEMBL279430 ZINC95608301 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041654 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1cscn1)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C34H49N9O10S/c1-16(2)27(33(52)37-13-25(36)45)43-34(53)28(17(3)4)42-32(51)24(12-26(46)47)41-31(50)23(11-20-14-54-15-38-20)40-29(48)18(5)39-30(49)22(35)10-19-6-8-21(44)9-7-19/h6-9,14-18,22-24,27-28,44H,10-13,35H2,1-5H3,(H2,36,45)(H,37,52)(H,39,49)(H,40,48)(H,41,50)(H,42,51)(H,43,53)(H,46,47)/t18-,22-,23-,24-,27-,28-/m0/s1 STGKSWSPWGABMM-YNTMFAKQSA-N 50034242 (S)-3-((S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-thiazol-4-yl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL283802 Mu-type opioid receptor Cavia cutleri 2800 ChEMBL 10.1021/jm00007a020 10.7270/Q21835J2 7707326 Heyl, DL; Dandabathula, M; Kurtz, KR; Mousigian, C Eastern Michigan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034242 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034242&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44457667 103942446 CHEMBL283802 ZINC95608501 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041657 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1c(C)c(C)c(C)c(C)c1C)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C42H62N8O10/c1-19(2)35(41(59)45-18-33(44)52)50-42(60)36(20(3)4)49-40(58)32(17-34(53)54)48-39(57)31(16-29-24(8)22(6)21(5)23(7)25(29)9)47-37(55)26(10)46-38(56)30(43)15-27-11-13-28(51)14-12-27/h11-14,19-20,26,30-32,35-36,51H,15-18,43H2,1-10H3,(H2,44,52)(H,45,59)(H,46,56)(H,47,55)(H,48,57)(H,49,58)(H,50,60)(H,53,54)/t26-,30-,31-,32-,35-,36-/m0/s1 GLVGLEWNIBLSII-JMJHPKHCSA-N 50034243 (S)-3-((S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-pentamethylphenyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL281634 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm00007a020 10.7270/Q21835J2 7707326 Heyl, DL; Dandabathula, M; Kurtz, KR; Mousigian, C Eastern Michigan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034243 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034243&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44274467 103942447 CHEMBL281634 ZINC95542521 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041661 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1cccnc1)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C36H51N9O10/c1-18(2)29(35(54)40-17-27(38)47)45-36(55)30(19(3)4)44-34(53)26(15-28(48)49)43-33(52)25(14-22-7-6-12-39-16-22)42-31(50)20(5)41-32(51)24(37)13-21-8-10-23(46)11-9-21/h6-12,16,18-20,24-26,29-30,46H,13-15,17,37H2,1-5H3,(H2,38,47)(H,40,54)(H,41,51)(H,42,50)(H,43,52)(H,44,53)(H,45,55)(H,48,49)/t20-,24-,25-,26-,29-,30-/m0/s1 RNOHJNOPQBIUAQ-QCYKOXEBSA-N 50034250 (S)-3-((S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-pyridin-3-yl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL22054 Mu-type opioid receptor Cavia cutleri 10000 ChEMBL 10.1021/jm00007a020 10.7270/Q21835J2 7707326 Heyl, DL; Dandabathula, M; Kurtz, KR; Mousigian, C Eastern Michigan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034250 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034250&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44274561 103942454 CHEMBL22054 ZINC95607106 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041664 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccc(F)cc1)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C37H51FN8O10/c1-18(2)30(36(55)41-17-28(40)48)46-37(56)31(19(3)4)45-35(54)27(16-29(49)50)44-34(53)26(15-22-6-10-23(38)11-7-22)43-32(51)20(5)42-33(52)25(39)14-21-8-12-24(47)13-9-21/h6-13,18-20,25-27,30-31,47H,14-17,39H2,1-5H3,(H2,40,48)(H,41,55)(H,42,52)(H,43,51)(H,44,53)(H,45,54)(H,46,56)(H,49,50)/t20-,25-,26-,27-,30-,31-/m0/s1 MCZQOXNSCXTMMV-NKSUJDJASA-N 50034246 (S)-3-[(S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-(4-fluoro-phenyl)-propionylamino]-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL283330 Mu-type opioid receptor Cavia cutleri 10000 ChEMBL 10.1021/jm00007a020 10.7270/Q21835J2 7707326 Heyl, DL; Dandabathula, M; Kurtz, KR; Mousigian, C Eastern Michigan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034246 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034246&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44274454 103942450 CHEMBL283330 ZINC95608536 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041668 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C34H50N10O10/c1-16(2)27(33(53)38-14-25(36)46)44-34(54)28(17(3)4)43-32(52)24(12-26(47)48)42-31(51)23(11-20-13-37-15-39-20)41-29(49)18(5)40-30(50)22(35)10-19-6-8-21(45)9-7-19/h6-9,13,15-18,22-24,27-28,45H,10-12,14,35H2,1-5H3,(H2,36,46)(H,37,39)(H,38,53)(H,40,50)(H,41,49)(H,42,51)(H,43,52)(H,44,54)(H,47,48)/t18-,22-,23-,24-,27-,28-/m0/s1 KPKLKHNZIHLGRE-YNTMFAKQSA-N 50034245 (S)-3-[(S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-(3H-imidazol-4-yl)-propionylamino]-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL21970 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm00007a020 10.7270/Q21835J2 7707326 Heyl, DL; Dandabathula, M; Kurtz, KR; Mousigian, C Eastern Michigan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034245 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034245&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44457676 103942449 CHEMBL21970 ZINC95540771 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041720 Oc1ccc2CC3N(CC4CC4)CCC45[C@@H](Oc1c24)c1c(C[C@@]35O)c2ccccc2n1Cc1cccc(c1)N=C=S InChI=1S/C34H31N3O3S/c38-27-11-10-22-15-28-34(39)16-25-24-6-1-2-7-26(24)37(18-21-4-3-5-23(14-21)35-19-41)30(25)32-33(34,29(22)31(27)40-32)12-13-36(28)17-20-8-9-20/h1-7,10-11,14,20,28,32,38-39H,8-9,12-13,15-18H2/t28?,32-,33?,34+/m0/s1 JQKFCNUCPHRFHS-KZRDDEGVSA-N 50034408 22-cyclopropylmethyl-11-(3-isothiocyanatobenzyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaene-2,16-diol::CHEMBL280649 Mu-type opioid receptor Cavia cutleri 66 ChEMBL 10.1021/jm00008a012 10.7270/Q2416W3K 7731019 Korlipara, VL; Takemori, AE; Portoghese, PS University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034408 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034408&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44276213 103942609 CHEMBL280649 ZINC28763460 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041721 Oc1ccc2CC3N(CC4CC4)CCC45[C@@H](Oc1c24)c1c(C[C@@]35O)c2ccccc2n1Cc1ccc(cc1)N=C=S InChI=1S/C34H31N3O3S/c38-27-12-9-22-15-28-34(39)16-25-24-3-1-2-4-26(24)37(18-21-7-10-23(11-8-21)35-19-41)30(25)32-33(34,29(22)31(27)40-32)13-14-36(28)17-20-5-6-20/h1-4,7-12,20,28,32,38-39H,5-6,13-18H2/t28?,32-,33?,34+/m0/s1 OXVIDGHUFWUYCY-KZRDDEGVSA-N 50034406 22-cyclopropylmethyl-11-(4-isothiocyanatobenzyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaene-2,16-diol::CHEMBL282107 Mu-type opioid receptor Cavia cutleri 289 ChEMBL 10.1021/jm00008a012 10.7270/Q2416W3K 7731019 Korlipara, VL; Takemori, AE; Portoghese, PS University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034406 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034406&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44276293 103942607 CHEMBL282107 ZINC28764084 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041724 Oc1ccc2CC3N(CC4CC4)CCC45[C@@H](Oc1c24)c1c(C[C@@]35O)c2ccccc2n1Cc1ccccc1N=C=S InChI=1S/C34H31N3O3S/c38-27-12-11-21-15-28-34(39)16-24-23-6-2-4-8-26(23)37(18-22-5-1-3-7-25(22)35-19-41)30(24)32-33(34,29(21)31(27)40-32)13-14-36(28)17-20-9-10-20/h1-8,11-12,20,28,32,38-39H,9-10,13-18H2/t28?,32-,33?,34+/m0/s1 JCQWJWBJYMMVMR-KZRDDEGVSA-N 50034405 22-cyclopropylmethyl-11-(2-isothiocyanatobenzyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaene-2,16-diol::CHEMBL26648 Mu-type opioid receptor Cavia cutleri 151 ChEMBL 10.1021/jm00008a012 10.7270/Q2416W3K 7731019 Korlipara, VL; Takemori, AE; Portoghese, PS University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034405 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034405&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44276292 103942606 CHEMBL26648 ZINC28763952 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041727 Oc1ccc2CC3N(CC4CC4)CCC45[C@@H](Oc1c24)c1c(C[C@@]35O)c2ccccc2n1Cc1cccc(NC(=O)CBr)c1 InChI=1S/C35H34BrN3O4/c36-17-29(41)37-23-5-3-4-21(14-23)19-39-26-7-2-1-6-24(26)25-16-35(42)28-15-22-10-11-27(40)32-30(22)34(35,33(43-32)31(25)39)12-13-38(28)18-20-8-9-20/h1-7,10-11,14,20,28,33,40,42H,8-9,12-13,15-19H2,(H,37,41)/t28?,33-,34?,35+/m0/s1 HDUSMYFDADSZOJ-FWJDJVLASA-N 50034407 1N-{3-[22-cyclopropylmethyl-2,16-dihydroxy-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaen-11-ylmethyl]phenyl}-2-bromoacetamide::CHEMBL282518 Mu-type opioid receptor Cavia cutleri 15 ChEMBL 10.1021/jm00008a012 10.7270/Q2416W3K 7731019 Korlipara, VL; Takemori, AE; Portoghese, PS University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034407 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034407&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44276269 103942608 CHEMBL282518 ZINC28762739 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50041990 CN1CCC2(CC1Cc1[nH]c3ccccc3c21)c1cccc(O)c1 InChI=1S/C21H22N2O/c1-23-10-9-21(14-5-4-6-16(24)11-14)13-15(23)12-19-20(21)17-7-2-3-8-18(17)22-19/h2-8,11,15,22,24H,9-10,12-13H2,1H3 WMJAKEDTFIYKBZ-UHFFFAOYSA-N 50034600 (+) 3-[13-methyl-9,13-diazatetracyclo[10.3.1.02,10.03,8]hexadeca-2(10),3(8),4,6-tetraen-1-yl]phenol::(-) 1,2,3,4,5,11-Hexahydro-6-(2-hydroxy)phenyl-3-methyl-2,6-methano-6H-azocino[4,5-b]indole::(-) 3-[13-methyl-9,13-diazatetracyclo[10.3.1.02,10.03,8]hexadeca-2(10),3(8),4,6-tetraen-1-yl]phenol::1,2,3,4,5,11-Hexahydro-6-(2-hydroxy)phenyl-3-methyl-2,6-methano-6H-azocino[4,5-b]indole::3-[13-methyl-9,13-diazatetracyclo[10.3.1.02,10.03,8]hexadeca-2(10),3(8),4,6-tetraen-1-yl]phenol::CHEMBL290301 Mu-type opioid receptor Cavia cutleri 2070 ChEMBL 10.1021/jm00009a013 10.7270/Q2MG7Q5M 7739011 Bertha, CM; Flippen-Anderson, JL; Rothman, RB; Porreca, F; Davis, P; Xu, H; Becketts, K; Cha, XY; Rice, KC National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034600 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034600&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44285619 103942766 CHEMBL290301 ZINC13741135 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50042005 CN1CCC2(CCCC1C2)c1cccc(O)c1 InChI=1S/C15H21NO/c1-16-9-8-15(7-3-5-13(16)11-15)12-4-2-6-14(17)10-12/h2,4,6,10,13,17H,3,5,7-9,11H2,1H3 ZQJGRSYDDMBMPJ-UHFFFAOYSA-N 50000570 3-(2-Methyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenol::CHEMBL285250 Mu-type opioid receptor Cavia cutleri 169 ChEMBL 10.1021/jm00009a013 10.7270/Q2MG7Q5M 7739011 Bertha, CM; Flippen-Anderson, JL; Rothman, RB; Porreca, F; Davis, P; Xu, H; Becketts, K; Cha, XY; Rice, KC National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000570&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 12368881 103915118 CHEMBL285250 ZINC05966698 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50042008 CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23-,24-/m0/s1 MCMMCRYPQBNCPH-DVKRWUGUSA-N 50001683 13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid::7-Benzyl-10-{[3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL294616::DPDPE Mu-type opioid receptor Cavia cutleri 7300 ChEMBL 10.1021/jm00009a013 10.7270/Q2MG7Q5M 7739011 Bertha, CM; Flippen-Anderson, JL; Rothman, RB; Porreca, F; Davis, P; Xu, H; Becketts, K; Cha, XY; Rice, KC National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001683&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299404 103916113 CHEMBL294616 ZINC27520031 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50042015 CC(C)C[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C29H39N5O7/c1-17(2)13-24(29(40)41)34-28(39)23(15-19-7-5-4-6-8-19)33-25(36)16-31-26(37)18(3)32-27(38)22(30)14-20-9-11-21(35)12-10-20/h4-12,17-18,22-24,35H,13-16,30H2,1-3H3,(H,31,37)(H,32,38)(H,33,36)(H,34,39)(H,40,41)/t18-,22+,23+,24-/m1/s1 ZHUJMSMQIPIPTF-IBURTVSXSA-N 21025 (2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanamido]-4-methylpentanoic acid::(D-Ala2,D-Leu5)-Enkephalin::BW-180C::CHEMBL340032::DADLE::DADLE-OH::H-Tyr-D-Ala-Gly-Phe-D-Leu-OH::[D-Ala2-D-Leu5]enkephalin Mu-type opioid receptor Cavia cutleri 29 ChEMBL 10.1021/jm00009a013 10.7270/Q2MG7Q5M 7739011 Bertha, CM; Flippen-Anderson, JL; Rothman, RB; Porreca, F; Davis, P; Xu, H; Becketts, K; Cha, XY; Rice, KC National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21025&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 6917707 49689098 CHEMBL340032 ZINC14952092 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50045648 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCCNC(=O)C[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@@H](CC(C)C)C(=O)N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@@H]1C(=O)N[C@H](CCCCN)C(N)=O InChI=1S/C65H104N20O13/c1-5-38(4)53(62(97)81-46(21-14-30-75-65(71)72)63(98)85-31-15-22-50(85)61(96)78-43(54(68)89)18-9-11-27-66)84-58(93)45(20-13-29-74-64(69)70)79-57(92)44-19-10-12-28-73-51(87)35-49(82-55(90)42(67)33-40-23-25-41(86)26-24-40)56(91)76-36-52(88)77-48(34-39-16-7-6-8-17-39)60(95)83-47(32-37(2)3)59(94)80-44/h6-8,16-17,23-26,37-38,42-50,53,86H,5,9-15,18-22,27-36,66-67H2,1-4H3,(H2,68,89)(H,73,87)(H,76,91)(H,77,88)(H,78,96)(H,79,92)(H,80,94)(H,81,97)(H,82,90)(H,83,95)(H,84,93)(H4,69,70,74)(H4,71,72,75)/t38-,42-,43+,44-,45-,46-,47-,48+,49-,50+,53-/m0/s1 WSIGXVIJXZJQQB-IKCYIKGESA-N 50051178 CHEMBL413011::Cyclic Lactam Peptide Analogues of Dynorphin A(1-11)-NH2Cyclic Lactam Peptide Analogues of Dynorphin A(1-11)-NH2 Mu-type opioid receptor Cavia cutleri 3.4 ChEMBL 10.1021/jm950369c 10.7270/Q2X63M13 8676350 Lung, FD; Collins, N; Stropova, D; Davis, P; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051178 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051178&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269677 103948176 CHEMBL413011 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50045650 CC[C@H](C)[C@H](NC(=O)[C@H]1CCCCNC(=O)C[C@@H](NC(=O)CNC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](Cc2ccccc2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCCNC(N)=N)C(=O)N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@@H]1C(=O)N[C@H](CCCCN)C(N)=O InChI=1S/C65H104N20O13/c1-5-38(4)53(62(97)81-46(21-14-30-75-65(71)72)63(98)85-31-15-22-50(85)61(96)78-43(54(68)89)18-9-11-27-66)84-57(92)44-19-10-12-28-73-51(87)35-49(77-52(88)36-76-55(90)42(67)33-40-23-25-41(86)26-24-40)60(95)83-48(34-39-16-7-6-8-17-39)59(94)82-47(32-37(2)3)58(93)80-45(56(91)79-44)20-13-29-74-64(69)70/h6-8,16-17,23-26,37-38,42-50,53,86H,5,9-15,18-22,27-36,66-67H2,1-4H3,(H2,68,89)(H,73,87)(H,76,90)(H,77,88)(H,78,96)(H,79,91)(H,80,93)(H,81,97)(H,82,94)(H,83,95)(H,84,92)(H4,69,70,74)(H4,71,72,75)/t38-,42-,43+,44+,45+,46-,47-,48+,49+,50+,53-/m0/s1 DTOXTAPVGGMSBI-DVDZSZLESA-N 50051172 CHEMBL386170::Cyclic Lactam Peptide Analogues of Dynorphin A(1-11)-NH2 Mu-type opioid receptor Cavia cutleri 740 ChEMBL 10.1021/jm950369c 10.7270/Q2X63M13 8676350 Lung, FD; Collins, N; Stropova, D; Davis, P; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051172 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051172&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269678 103948170 CHEMBL386170 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50045653 CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@@H]1C(=O)N[C@H](CCCCN)C(N)=O InChI=1S/C65H106N20O14/c1-5-38(4)53(62(98)81-46(21-14-30-75-65(72)73)63(99)85-31-15-22-50(85)61(97)78-43(54(69)90)18-9-11-27-66)84-57(93)44(19-10-12-28-67)79-56(92)45(20-13-29-74-64(70)71)80-58(94)47(32-37(2)3)82-59(95)48(34-39-16-7-6-8-17-39)83-60(96)49(35-52(88)89)77-51(87)36-76-55(91)42(68)33-40-23-25-41(86)26-24-40/h6-8,16-17,23-26,37-38,42-50,53,86H,5,9-15,18-22,27-36,66-68H2,1-4H3,(H2,69,90)(H,76,91)(H,77,87)(H,78,97)(H,79,92)(H,80,94)(H,81,98)(H,82,95)(H,83,96)(H,84,93)(H,88,89)(H4,70,71,74)(H4,72,73,75)/t38-,42-,43+,44-,45-,46-,47-,48-,49-,50+,53-/m0/s1 UIMVBCHLURBLDP-NNCQYVRSSA-N 50051181 CHEMBL387437::Cyclic Lactam Peptide Analogues of Dynorphin A(1-11)-NH2 Mu-type opioid receptor Cavia cutleri 1320 ChEMBL 10.1021/jm950369c 10.7270/Q2X63M13 8676350 Lung, FD; Collins, N; Stropova, D; Davis, P; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051181&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269732 103948179 CHEMBL387437 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50045654 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@@H]1C(=O)N[C@H](CCCCN)C(N)=O InChI=1S/C63H104N22O12/c1-5-37(4)51(59(96)82-45(20-13-29-75-63(71)72)60(97)85-30-14-21-48(85)58(95)79-42(52(66)89)17-9-10-26-64)84-55(92)44(19-12-28-74-62(69)70)80-54(91)43(18-11-27-73-61(67)68)81-56(93)46(31-36(2)3)83-57(94)47(33-38-15-7-6-8-16-38)78-50(88)35-76-49(87)34-77-53(90)41(65)32-39-22-24-40(86)25-23-39/h6-8,15-16,22-25,36-37,41-48,51,86H,5,9-14,17-21,26-35,64-65H2,1-4H3,(H2,66,89)(H,76,87)(H,77,90)(H,78,88)(H,79,95)(H,80,91)(H,81,93)(H,82,96)(H,83,94)(H,84,92)(H4,67,68,73)(H4,69,70,74)(H4,71,72,75)/t37-,41-,42+,43-,44-,45-,46-,47-,48+,51-/m0/s1 OKJAOUBQLSWUNX-QICLASASSA-N 50051169 CHEMBL409974::Cyclic Lactam Peptide Analogues of Dynorphin A(1-11)-NH2 Mu-type opioid receptor Cavia cutleri 9.9 ChEMBL 10.1021/jm950369c 10.7270/Q2X63M13 8676350 Lung, FD; Collins, N; Stropova, D; Davis, P; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051169 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051169&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269736 103948167 CHEMBL409974 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50045655 CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@@H]1C(=O)N[C@H](CCCCN)C(N)=O InChI=1S/C65H106N20O14/c1-5-38(4)53(62(98)81-46(21-14-30-75-65(72)73)63(99)85-31-15-22-50(85)61(97)78-43(54(69)90)18-9-11-27-66)84-57(93)44(19-10-12-28-67)79-56(92)45(20-13-29-74-64(70)71)80-58(94)47(32-37(2)3)82-59(95)48(34-39-16-7-6-8-17-39)83-60(96)49(35-52(88)89)77-51(87)36-76-55(91)42(68)33-40-23-25-41(86)26-24-40/h6-8,16-17,23-26,37-38,42-50,53,86H,5,9-15,18-22,27-36,66-68H2,1-4H3,(H2,69,90)(H,76,91)(H,77,87)(H,78,97)(H,79,92)(H,80,94)(H,81,98)(H,82,95)(H,83,96)(H,84,93)(H,88,89)(H4,70,71,74)(H4,72,73,75)/t38-,42-,43+,44-,45-,46-,47-,48-,49+,50+,53-/m0/s1 UIMVBCHLURBLDP-ARLUFQQFSA-N 50051176 CHEMBL277132::Cyclic Lactam Peptide Analogues of Dynorphin A(1-11)-NH2 Mu-type opioid receptor Cavia cutleri 660 ChEMBL 10.1021/jm950369c 10.7270/Q2X63M13 8676350 Lung, FD; Collins, N; Stropova, D; Davis, P; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051176&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269731 103948174 CHEMBL277132 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50045656 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N1CCC[C@@H]1C(=O)N[C@H](CCCCN)C(N)=O InChI=1S/C61H98N20O14/c1-3-35(2)50(58(94)79-45(32-49(85)86)59(95)81-29-13-20-46(81)57(93)75-40(51(65)87)16-7-9-25-62)80-55(91)43(19-12-28-71-61(68)69)77-54(90)42(18-11-27-70-60(66)67)76-53(89)41(17-8-10-26-63)78-56(92)44(31-36-14-5-4-6-15-36)74-48(84)34-72-47(83)33-73-52(88)39(64)30-37-21-23-38(82)24-22-37/h4-6,14-15,21-24,35,39-46,50,82H,3,7-13,16-20,25-34,62-64H2,1-2H3,(H2,65,87)(H,72,83)(H,73,88)(H,74,84)(H,75,93)(H,76,89)(H,77,90)(H,78,92)(H,79,94)(H,80,91)(H,85,86)(H4,66,67,70)(H4,68,69,71)/t35-,39-,40+,41-,42-,43-,44-,45-,46+,50-/m0/s1 XTJXDIBDHVAUKE-RTQUJWAISA-N 50051171 CHEMBL384485::Cyclic Lactam Peptide Analogues of Dynorphin A(1-11)-NH2 Mu-type opioid receptor Cavia cutleri 400 ChEMBL 10.1021/jm950369c 10.7270/Q2X63M13 8676350 Lung, FD; Collins, N; Stropova, D; Davis, P; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051171&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269730 103948169 CHEMBL384485 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50045661 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@H](CC(O)=O)C(=O)N1CCC[C@@H]1C(=O)N[C@H](CCCCN)C(N)=O InChI=1S/C61H98N20O14/c1-3-35(2)50(58(94)79-45(32-49(85)86)59(95)81-29-13-20-46(81)57(93)75-40(51(65)87)16-7-9-25-62)80-55(91)43(19-12-28-71-61(68)69)77-54(90)42(18-11-27-70-60(66)67)76-53(89)41(17-8-10-26-63)78-56(92)44(31-36-14-5-4-6-15-36)74-48(84)34-72-47(83)33-73-52(88)39(64)30-37-21-23-38(82)24-22-37/h4-6,14-15,21-24,35,39-46,50,82H,3,7-13,16-20,25-34,62-64H2,1-2H3,(H2,65,87)(H,72,83)(H,73,88)(H,74,84)(H,75,93)(H,76,89)(H,77,90)(H,78,92)(H,79,94)(H,80,91)(H,85,86)(H4,66,67,70)(H4,68,69,71)/t35-,39-,40+,41-,42-,43-,44-,45+,46+,50-/m0/s1 XTJXDIBDHVAUKE-ATGAETPHSA-N 50051179 CHEMBL412580::Cyclic Lactam Peptide Analogues of Dynorphin A(1-11)-NH2 Mu-type opioid receptor Cavia cutleri 555 ChEMBL 10.1021/jm950369c 10.7270/Q2X63M13 8676350 Lung, FD; Collins, N; Stropova, D; Davis, P; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051179 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051179&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269737 103948177 CHEMBL412580 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50045667 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@@H]1C(=O)N[C@H](CCCCN)C(N)=O InChI=1S/C65H106N20O14/c1-5-38(4)53(62(98)81-46(21-14-30-75-65(72)73)63(99)85-31-15-22-50(85)61(97)78-43(54(69)90)18-9-11-27-66)84-58(94)45(20-13-29-74-64(70)71)79-57(93)44(19-10-12-28-67)80-59(95)47(32-37(2)3)83-60(96)48(34-39-16-7-6-8-17-39)77-51(87)36-76-56(92)49(35-52(88)89)82-55(91)42(68)33-40-23-25-41(86)26-24-40/h6-8,16-17,23-26,37-38,42-50,53,86H,5,9-15,18-22,27-36,66-68H2,1-4H3,(H2,69,90)(H,76,92)(H,77,87)(H,78,97)(H,79,93)(H,80,95)(H,81,98)(H,82,91)(H,83,96)(H,84,94)(H,88,89)(H4,70,71,74)(H4,72,73,75)/t38-,42-,43+,44-,45-,46-,47-,48-,49-,50+,53-/m0/s1 ATQGWVKUEJVILJ-NNCQYVRSSA-N 50051173 CHEMBL217049::Cyclic Lactam Peptide Analogues of Dynorphin A(1-11)-NH2 Mu-type opioid receptor Cavia cutleri 0.080000 ChEMBL 10.1021/jm950369c 10.7270/Q2X63M13 8676350 Lung, FD; Collins, N; Stropova, D; Davis, P; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051173&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269750 103948171 CHEMBL217049 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50045668 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@@H]1C(=O)N[C@H](CCCCN)C(N)=O InChI=1S/C65H106N20O14/c1-5-38(4)53(62(98)81-46(21-14-30-75-65(72)73)63(99)85-31-15-22-50(85)61(97)78-43(54(69)90)18-9-11-27-66)84-58(94)45(20-13-29-74-64(70)71)79-57(93)44(19-10-12-28-67)80-59(95)47(32-37(2)3)83-60(96)48(34-39-16-7-6-8-17-39)77-51(87)36-76-56(92)49(35-52(88)89)82-55(91)42(68)33-40-23-25-41(86)26-24-40/h6-8,16-17,23-26,37-38,42-50,53,86H,5,9-15,18-22,27-36,66-68H2,1-4H3,(H2,69,90)(H,76,92)(H,77,87)(H,78,97)(H,79,93)(H,80,95)(H,81,98)(H,82,91)(H,83,96)(H,84,94)(H,88,89)(H4,70,71,74)(H4,72,73,75)/t38-,42-,43+,44-,45-,46-,47-,48-,49+,50+,53-/m0/s1 ATQGWVKUEJVILJ-ARLUFQQFSA-N 50051177 CHEMBL264733::Cyclic Lactam Peptide Analogues of Dynorphin A(1-11)-NH2 Mu-type opioid receptor Cavia cutleri 290 ChEMBL 10.1021/jm950369c 10.7270/Q2X63M13 8676350 Lung, FD; Collins, N; Stropova, D; Davis, P; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051177 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051177&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269751 103948175 CHEMBL264733 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50045670 CC[C@@H](C)[C@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)C[C@H](NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@H](CCCCN)C(N)=O)NC(=O)[C@@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@H](N)Cc1ccc(O)cc1 InChI=1S/C61H96N20O13/c1-3-35(2)50-58(93)79-45(59(94)81-29-13-20-46(81)57(92)75-40(51(64)86)16-7-9-25-62)32-47(83)69-26-10-8-17-41(53(88)76-42(18-11-27-70-60(65)66)54(89)77-43(55(90)80-50)19-12-28-71-61(67)68)78-56(91)44(31-36-14-5-4-6-15-36)74-49(85)34-72-48(84)33-73-52(87)39(63)30-37-21-23-38(82)24-22-37/h4-6,14-15,21-24,35,39-46,50,82H,3,7-13,16-20,25-34,62-63H2,1-2H3,(H2,64,86)(H,69,83)(H,72,84)(H,73,87)(H,74,85)(H,75,92)(H,76,88)(H,77,89)(H,78,91)(H,79,93)(H,80,90)(H4,65,66,70)(H4,67,68,71)/t35-,39-,40-,41-,42-,43+,44-,45+,46+,50-/m1/s1 AAMCVRWFZKNHTH-GILCVNLZSA-N 50051180 CHEMBL387083::Cyclic Lactam Peptide Analogues of Dynorphin A(1-11)-NH2 Mu-type opioid receptor Cavia cutleri 12 ChEMBL 10.1021/jm950369c 10.7270/Q2X63M13 8676350 Lung, FD; Collins, N; Stropova, D; Davis, P; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051180 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051180&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269752 103948178 CHEMBL387083 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50045672 CC[C@@H](C)[C@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCNC(=O)C[C@@H](NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@H](CCCCN)C(N)=O)NC(=O)[C@@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@H](N)Cc1ccc(O)cc1 InChI=1S/C61H96N20O13/c1-3-35(2)50-58(93)79-45(59(94)81-29-13-20-46(81)57(92)75-40(51(64)86)16-7-9-25-62)32-47(83)69-26-10-8-17-41(53(88)76-42(18-11-27-70-60(65)66)54(89)77-43(55(90)80-50)19-12-28-71-61(67)68)78-56(91)44(31-36-14-5-4-6-15-36)74-49(85)34-72-48(84)33-73-52(87)39(63)30-37-21-23-38(82)24-22-37/h4-6,14-15,21-24,35,39-46,50,82H,3,7-13,16-20,25-34,62-63H2,1-2H3,(H2,64,86)(H,69,83)(H,72,84)(H,73,87)(H,74,85)(H,75,92)(H,76,88)(H,77,89)(H,78,91)(H,79,93)(H,80,90)(H4,65,66,70)(H4,67,68,71)/t35-,39-,40-,41-,42-,43+,44-,45-,46+,50-/m1/s1 AAMCVRWFZKNHTH-AKSNCSMTSA-N 50051170 CHEMBL412600::Cyclic Lactam Peptide Analogues of Dynorphin A(1-11)-NH2 Mu-type opioid receptor Cavia cutleri 120 ChEMBL 10.1021/jm950369c 10.7270/Q2X63M13 8676350 Lung, FD; Collins, N; Stropova, D; Davis, P; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051170 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051170&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269681 103948168 CHEMBL412600 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50045706 CC[C@H](C)[C@H](NC(=O)[C@H]1CCCCNC(=O)C[C@H](NC(=O)CNC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@H](Cc2ccccc2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCCNC(N)=N)C(=O)N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@@H]1C(=O)N[C@H](CCCCN)C(N)=O InChI=1S/C65H104N20O13/c1-5-38(4)53(62(97)81-46(21-14-30-75-65(71)72)63(98)85-31-15-22-50(85)61(96)78-43(54(68)89)18-9-11-27-66)84-57(92)44-19-10-12-28-73-51(87)35-49(77-52(88)36-76-55(90)42(67)33-40-23-25-41(86)26-24-40)60(95)83-48(34-39-16-7-6-8-17-39)59(94)82-47(32-37(2)3)58(93)80-45(56(91)79-44)20-13-29-74-64(69)70/h6-8,16-17,23-26,37-38,42-50,53,86H,5,9-15,18-22,27-36,66-67H2,1-4H3,(H2,68,89)(H,73,87)(H,76,90)(H,77,88)(H,78,96)(H,79,91)(H,80,93)(H,81,97)(H,82,94)(H,83,95)(H,84,92)(H4,69,70,74)(H4,71,72,75)/t38-,42-,43+,44+,45+,46-,47-,48+,49-,50+,53-/m0/s1 DTOXTAPVGGMSBI-OCVCKPGLSA-N 50051174 CHEMBL216182::Cyclic Lactam Peptide Analogues of Dynorphin A(1-11)-NH2 Mu-type opioid receptor Cavia cutleri 310 ChEMBL 10.1021/jm950369c 10.7270/Q2X63M13 8676350 Lung, FD; Collins, N; Stropova, D; Davis, P; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051174 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051174&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269682 103948172 CHEMBL216182 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50045707 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCCNC(=O)C[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@@H](CC(C)C)C(=O)N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@@H]1C(=O)N[C@H](CCCCN)C(N)=O InChI=1S/C65H104N20O13/c1-5-38(4)53(62(97)81-46(21-14-30-75-65(71)72)63(98)85-31-15-22-50(85)61(96)78-43(54(68)89)18-9-11-27-66)84-58(93)45(20-13-29-74-64(69)70)79-57(92)44-19-10-12-28-73-51(87)35-49(82-55(90)42(67)33-40-23-25-41(86)26-24-40)56(91)76-36-52(88)77-48(34-39-16-7-6-8-17-39)60(95)83-47(32-37(2)3)59(94)80-44/h6-8,16-17,23-26,37-38,42-50,53,86H,5,9-15,18-22,27-36,66-67H2,1-4H3,(H2,68,89)(H,73,87)(H,76,91)(H,77,88)(H,78,96)(H,79,92)(H,80,94)(H,81,97)(H,82,90)(H,83,95)(H,84,93)(H4,69,70,74)(H4,71,72,75)/t38-,42-,43+,44-,45-,46-,47-,48+,49+,50+,53-/m0/s1 WSIGXVIJXZJQQB-IPIYZFISSA-N 50051175 CHEMBL415339::Cyclic Lactam Peptide Analogues of Dynorphin A(1-11)-NH2 Mu-type opioid receptor Cavia cutleri 2980 ChEMBL 10.1021/jm950369c 10.7270/Q2X63M13 8676350 Lung, FD; Collins, N; Stropova, D; Davis, P; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051175 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051175&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269673 103948173 CHEMBL415339 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50048052 CN[C@@H](Cc1c(C)cc(O)cc1C)C(=O)N1Cc2ccccc2CC1C(N)=O InChI=1S/C22H27N3O3/c1-13-8-17(26)9-14(2)18(13)11-19(24-3)22(28)25-12-16-7-5-4-6-15(16)10-20(25)21(23)27/h4-9,19-20,24,26H,10-12H2,1-3H3,(H2,23,27)/t19-,20?/m0/s1 OPHUJOIWOCVSQQ-XJDOXCRVSA-N 50060076 2-[(S)-3-(4-Hydroxy-2,6-dimethyl-phenyl)-2-methylamino-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid amide::CHEMBL107386 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm9607663 10.7270/Q2TD9Z1N 9301674 Salvadori, S; Balboni, G; Guerrini, R; Tomatis, R; Bianchi, C; Bryant, SD; Cooper, PS; Lazarus, LH University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060076&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336096 103955848 CHEMBL107386 ZINC26840375 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50048053 CN(C)[C@H](Cc1c(C)cc(O)cc1C)C(=O)N1Cc2ccccc2CC1C(O)=O InChI=1S/C23H28N2O4/c1-14-9-18(26)10-15(2)19(14)12-20(24(3)4)22(27)25-13-17-8-6-5-7-16(17)11-21(25)23(28)29/h5-10,20-21,26H,11-13H2,1-4H3,(H,28,29)/t20-,21?/m1/s1 MDTMCHLPEWCDEO-VQCQRNETSA-N 50060064 2-[(R)-2-Dimethylamino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid::CHEMBL318395 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm9607663 10.7270/Q2TD9Z1N 9301674 Salvadori, S; Balboni, G; Guerrini, R; Tomatis, R; Bianchi, C; Bryant, SD; Cooper, PS; Lazarus, LH University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060064&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10668458 103955837 CHEMBL318395 ZINC26838367 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50048054 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(O)=O InChI=1S/C21H24N2O4/c1-12-7-16(24)8-13(2)17(12)10-18(22)20(25)23-11-15-6-4-3-5-14(15)9-19(23)21(26)27/h3-8,18-19,24H,9-11,22H2,1-2H3,(H,26,27)/t18-,19-/m0/s1 QBLVXTMPLLWZDE-OALUTQOASA-N 50299565 (S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid::CHEMBL571492::H-2',6'-dimethyltyrosine-Tic-OH::H-Dmt-Tic-OH Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm9607663 10.7270/Q2TD9Z1N 9301674 Salvadori, S; Balboni, G; Guerrini, R; Tomatis, R; Bianchi, C; Bryant, SD; Cooper, PS; Lazarus, LH University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50299565 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50299565&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15384271 104141094 CHEMBL571492 ZINC13472293 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50048055 CN[C@@H](Cc1c(C)cc(O)cc1C)C(=O)N1Cc2ccccc2CC1C(O)=O InChI=1S/C22H26N2O4/c1-13-8-17(25)9-14(2)18(13)11-19(23-3)21(26)24-12-16-7-5-4-6-15(16)10-20(24)22(27)28/h4-9,19-20,23,25H,10-12H2,1-3H3,(H,27,28)/t19-,20?/m0/s1 IJJCVNWFPAZCQT-XJDOXCRVSA-N 50060071 2-[(S)-3-(4-Hydroxy-2,6-dimethyl-phenyl)-2-methylamino-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid::CHEMBL104842 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm9607663 10.7270/Q2TD9Z1N 9301674 Salvadori, S; Balboni, G; Guerrini, R; Tomatis, R; Bianchi, C; Bryant, SD; Cooper, PS; Lazarus, LH University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060071&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336081 103955843 CHEMBL104842 ZINC26835421 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50048056 CN[C@@H](Cc1c(C)cc(O)cc1C)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](C)C(O)=O InChI=1S/C25H31N3O5/c1-14-9-19(29)10-15(2)20(14)12-21(26-4)24(31)28-13-18-8-6-5-7-17(18)11-22(28)23(30)27-16(3)25(32)33/h5-10,16,21-22,26,29H,11-13H2,1-4H3,(H,27,30)(H,32,33)/t16-,21-,22-/m0/s1 NETWGENZKBHHIR-SSKFGXFMSA-N 50060075 2-({2-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-propionic acid::CHEMBL2370388 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm9607663 10.7270/Q2TD9Z1N 9301674 Salvadori, S; Balboni, G; Guerrini, R; Tomatis, R; Bianchi, C; Bryant, SD; Cooper, PS; Lazarus, LH University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060075 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060075&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73351569 103955847 CHEMBL2370388 ZINC26832205 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50048058 CN[C@@H](Cc1c(C)cc(O)cc1C)C(=O)N1Cc2ccccc2CC1C(N)=O InChI=1S/C22H27N3O3/c1-13-8-17(26)9-14(2)18(13)11-19(24-3)22(28)25-12-16-7-5-4-6-15(16)10-20(25)21(23)27/h4-9,19-20,24,26H,10-12H2,1-3H3,(H2,23,27)/t19-,20?/m0/s1 OPHUJOIWOCVSQQ-XJDOXCRVSA-N 50060076 2-[(S)-3-(4-Hydroxy-2,6-dimethyl-phenyl)-2-methylamino-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid amide::CHEMBL107386 Mu-type opioid receptor Cavia cutleri 10000 ChEMBL 10.1021/jm9607663 10.7270/Q2TD9Z1N 9301674 Salvadori, S; Balboni, G; Guerrini, R; Tomatis, R; Bianchi, C; Bryant, SD; Cooper, PS; Lazarus, LH University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060076&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336096 103955848 CHEMBL107386 ZINC26840375 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50048061 CN(C)[C@@H](Cc1c(C)cc(O)cc1C)C(=O)N1Cc2ccccc2CC1C(O)=O InChI=1S/C23H28N2O4/c1-14-9-18(26)10-15(2)19(14)12-20(24(3)4)22(27)25-13-17-8-6-5-7-16(17)11-21(25)23(28)29/h5-10,20-21,26H,11-13H2,1-4H3,(H,28,29)/t20-,21?/m0/s1 MDTMCHLPEWCDEO-BGERDNNASA-N 50060068 2-[(S)-2-Dimethylamino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid::CHEMBL104436 Mu-type opioid receptor Cavia cutleri 1585 ChEMBL 10.1021/jm9607663 10.7270/Q2TD9Z1N 9301674 Salvadori, S; Balboni, G; Guerrini, R; Tomatis, R; Bianchi, C; Bryant, SD; Cooper, PS; Lazarus, LH University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060068 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060068&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336032 103955840 CHEMBL104436 ZINC26834468 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50048062 CN[C@H](Cc1c(C)cc(O)cc1C)C(=O)N1Cc2ccccc2CC1C(O)=O InChI=1S/C22H26N2O4/c1-13-8-17(25)9-14(2)18(13)11-19(23-3)21(26)24-12-16-7-5-4-6-15(16)10-20(24)22(27)28/h4-9,19-20,23,25H,10-12H2,1-3H3,(H,27,28)/t19-,20?/m1/s1 IJJCVNWFPAZCQT-FIWHBWSRSA-N 50060072 2-[(R)-3-(4-Hydroxy-2,6-dimethyl-phenyl)-2-methylamino-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid::CHEMBL107754 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm9607663 10.7270/Q2TD9Z1N 9301674 Salvadori, S; Balboni, G; Guerrini, R; Tomatis, R; Bianchi, C; Bryant, SD; Cooper, PS; Lazarus, LH University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060072&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10596072 103955844 CHEMBL107754 ZINC26840422 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50048064 C[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@H](N)Cc1c(C)cc(O)cc1C)C(O)=O InChI=1S/C24H29N3O5/c1-13-8-18(28)9-14(2)19(13)11-20(25)23(30)27-12-17-7-5-4-6-16(17)10-21(27)22(29)26-15(3)24(31)32/h4-9,15,20-21,28H,10-12,25H2,1-3H3,(H,26,29)(H,31,32)/t15-,20+,21-/m0/s1 TUXLEAJGNKFQRS-RVHYNSKXSA-N 50060083 2-({2-[(S)-2-Dimethylamino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-propionic acid::CHEMBL3038229 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm9607663 10.7270/Q2TD9Z1N 9301674 Salvadori, S; Balboni, G; Guerrini, R; Tomatis, R; Bianchi, C; Bryant, SD; Cooper, PS; Lazarus, LH University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060083 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060083&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73355833 103955855 CHEMBL3038229 ZINC26834479 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50048067 CN(C)[C@@H](Cc1c(C)cc(O)cc1C)C(=O)N1Cc2ccccc2CC1C(N)=O InChI=1S/C23H29N3O3/c1-14-9-18(27)10-15(2)19(14)12-21(25(3)4)23(29)26-13-17-8-6-5-7-16(17)11-20(26)22(24)28/h5-10,20-21,27H,11-13H2,1-4H3,(H2,24,28)/t20?,21-/m0/s1 MTUOGMXYYQVUNR-LBAQZLPGSA-N 50060065 2-[(S)-2-Dimethylamino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid amide::CHEMBL106853 Mu-type opioid receptor Cavia cutleri 501 ChEMBL 10.1021/jm9607663 10.7270/Q2TD9Z1N 9301674 Salvadori, S; Balboni, G; Guerrini, R; Tomatis, R; Bianchi, C; Bryant, SD; Cooper, PS; Lazarus, LH University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060065&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336001 103955838 CHEMBL106853 ZINC26839561 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50048072 CC(NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(O)=O InChI=1S/C24H29N3O5/c1-13-8-18(28)9-14(2)19(13)11-20(25)23(30)27-12-17-7-5-4-6-16(17)10-21(27)22(29)26-15(3)24(31)32/h4-9,15,20-21,28H,10-12,25H2,1-3H3,(H,26,29)(H,31,32)/t15?,20-,21-/m0/s1 TUXLEAJGNKFQRS-LBTAZEDMSA-N 50454645 CHEMBL2370384 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm9607663 10.7270/Q2TD9Z1N 9301674 Salvadori, S; Balboni, G; Guerrini, R; Tomatis, R; Bianchi, C; Bryant, SD; Cooper, PS; Lazarus, LH University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50454645 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50454645&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73353034 225146290 CHEMBL2370384 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50048074 C[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@H](Cc1c(C)cc(O)cc1C)N(C)C)C(O)=O InChI=1S/C26H33N3O5/c1-15-10-20(30)11-16(2)21(15)13-23(28(4)5)25(32)29-14-19-9-7-6-8-18(19)12-22(29)24(31)27-17(3)26(33)34/h6-11,17,22-23,30H,12-14H2,1-5H3,(H,27,31)(H,33,34)/t17-,22-,23-/m0/s1 BLDGRRAWEZASPT-RTFZILSDSA-N 50060082 2-({2-[(S)-3-(4-Hydroxy-2,6-dimethyl-phenyl)-2-methylamino-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-propionic acid::CHEMBL2370386 Mu-type opioid receptor Cavia cutleri 1585 ChEMBL 10.1021/jm9607663 10.7270/Q2TD9Z1N 9301674 Salvadori, S; Balboni, G; Guerrini, R; Tomatis, R; Bianchi, C; Bryant, SD; Cooper, PS; Lazarus, LH University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060082&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73353035 103955854 CHEMBL2370386 ZINC26835068 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50046315 CN([C@H](CN1CCCC1)c1cccc(NC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=S)N=C2C=CC(C(=C2)C(O)=O)=C2c3ccc(O)cc3Oc3cc(O)ccc23)c1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C50H48Cl2N8O10S/c1-59(47(67)18-28-7-14-38(51)39(52)17-28)40(27-60-15-2-3-16-60)29-5-4-6-30(19-29)57-46(66)26-55-44(64)24-53-43(63)23-54-45(65)25-56-50(71)58-31-8-11-34(37(20-31)49(68)69)48-35-12-9-32(61)21-41(35)70-42-22-33(62)10-13-36(42)48/h4-14,17,19-22,40,61-62H,2-3,15-16,18,23-27H2,1H3,(H,53,63)(H,54,65)(H,55,64)(H,56,71)(H,57,66)(H,68,69)/t40-/m1/s1 ZFAIYDCFNOMXDL-RRHRGVEJSA-N 50369224 CHEMBL1907787 Mu-type opioid receptor Cavia cutleri 631 ChEMBL 10.1021/jm950813b 10.7270/Q27S7PFG 8648612 Chang, AC; Chao, CC; Takemori, AE; Gekker, G; Hu, S; Peterson, PK; Portoghese, PS University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369224 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369224&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10796106 160848326 CHEMBL1907787 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50046317 CN([C@H](CN1CCCC1)c1cccc(NC(=O)CNC(=S)N=C2C=CC(C(=C2)C(O)=O)=C2c3ccc(O)cc3Oc3cc(O)ccc23)c1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C44H39Cl2N5O7S/c1-50(41(55)18-25-7-14-35(45)36(46)17-25)37(24-51-15-2-3-16-51)26-5-4-6-27(19-26)48-40(54)23-47-44(59)49-28-8-11-31(34(20-28)43(56)57)42-32-12-9-29(52)21-38(32)58-39-22-30(53)10-13-33(39)42/h4-14,17,19-22,37,52-53H,2-3,15-16,18,23-24H2,1H3,(H,47,59)(H,48,54)(H,56,57)/t37-/m1/s1 JJRIXPZOUAXUDC-DIPNUNPCSA-N 50369223 CHEMBL1907788 Mu-type opioid receptor Cavia cutleri 286 ChEMBL 10.1021/jm950813b 10.7270/Q27S7PFG 8648612 Chang, AC; Chao, CC; Takemori, AE; Gekker, G; Hu, S; Peterson, PK; Portoghese, PS University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369223&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10843252 160848325 CHEMBL1907788 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50046401 NC1=NC(=N[C@]11CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1C2(CCN3CC1CC1)c45)[C@]1(N)CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1C2(CCN3CC1CC1)c45 InChI=1S/C42H50N6O6/c43-35-40(10-12-42(52)28-18-24-6-8-26(50)32-30(24)38(42,34(40)54-32)14-16-48(28)20-22-3-4-22)46-36(45-35)39(44)9-11-41(51)27-17-23-5-7-25(49)31-29(23)37(41,33(39)53-31)13-15-47(27)19-21-1-2-21/h5-8,21-22,27-28,33-34,49-52H,1-4,9-20,44H2,(H2,43,45,46)/t27-,28-,33-,34-,37?,38?,39+,40+,41-,42-/m1/s1 UPCDLAYRPHHNOB-DQSJYHHLSA-N 50049563 5-amino-2,4(Bis-4-cyclopropylmethyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one) imidazole::CHEMBL299772 Mu-type opioid receptor Cavia cutleri 0.980000 ChEMBL 10.1021/jm950807f 10.7270/Q20865Z8 8627605 Bolognesi, ML; Ojala, WH; Gleason, WB; Griffin, JF; Farouz-Grant, F; Larson, DL; Takemori, AE; Portoghese, PS University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049563&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44297100 103979875 CHEMBL299772 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50046403 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@]1(CC[C@@]35O)NC(=O)NC1=O InChI=1S/C22H25N3O5/c26-13-4-3-12-9-14-22(29)6-5-21(18(27)23-19(28)24-21)17-20(22,15(12)16(13)30-17)7-8-25(14)10-11-1-2-11/h3-4,11,14,17,26,29H,1-2,5-10H2,(H2,23,24,27,28)/t14-,17-,20+,21+,22-/m1/s1 AXFDDKKRVFMVHY-OFAZKWMESA-N 50049561 CHEMBL430950::Naltrexone derivative Mu-type opioid receptor Cavia cutleri 71 ChEMBL 10.1021/jm950807f 10.7270/Q20865Z8 8627605 Bolognesi, ML; Ojala, WH; Gleason, WB; Griffin, JF; Farouz-Grant, F; Larson, DL; Takemori, AE; Portoghese, PS University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049561 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049561&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44297167 103979873 CHEMBL430950 ZINC29484605 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50046407 NC(=N)[C@]1(N)CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45 InChI=1S/C21H28N4O3/c22-18(23)20(24)5-6-21(27)14-9-12-3-4-13(26)16-15(12)19(21,17(20)28-16)7-8-25(14)10-11-1-2-11/h3-4,11,14,17,26-27H,1-2,5-10,24H2,(H3,22,23)/t14-,17-,19+,20+,21-/m1/s1 HPTFPXLXBSYPMG-STSJCENXSA-N 50049564 14-amino-14-amino(imino)methyl-4-cyclopropylmethyl-(13R,14R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-triene-10,17-diol::CHEMBL53963 Mu-type opioid receptor Cavia cutleri 18 ChEMBL 10.1021/jm950807f 10.7270/Q20865Z8 8627605 Bolognesi, ML; Ojala, WH; Gleason, WB; Griffin, JF; Farouz-Grant, F; Larson, DL; Takemori, AE; Portoghese, PS University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049564 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049564&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44297101 103979876 CHEMBL53963 ZINC29483349 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50046411 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1 DQCKKXVULJGBQN-XFWGSAIBSA-N 60212 (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::MLS000069607::NALTREXONE HYDROCHLORIDE::SMR000058767::US10988481, Compound NTX::US9107954, naltrexone::cid_5485201 Mu-type opioid receptor Cavia cutleri 0.750000 ChEMBL 10.1021/jm950807f 10.7270/Q20865Z8 8627605 Bolognesi, ML; Ojala, WH; Gleason, WB; Griffin, JF; Farouz-Grant, F; Larson, DL; Takemori, AE; Portoghese, PS University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60212&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5360515 252639834 DB00704 C07253 ZINC00001773 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50047630 CC(C)[C@H](NC(=O)[C@@H](NC(=O)C(C)(C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C37H54N8O8/c1-20(2)29(34(51)40-19-28(39)47)43-35(52)30(21(3)4)44-36(53)37(6,7)45-33(50)27(18-23-11-9-8-10-12-23)42-31(48)22(5)41-32(49)26(38)17-24-13-15-25(46)16-14-24/h8-16,20-22,26-27,29-30,46H,17-19,38H2,1-7H3,(H2,39,47)(H,40,51)(H,41,49)(H,42,48)(H,43,52)(H,44,53)(H,45,50)/t22-,26+,27+,29+,30+/m1/s1 HNNLSZAQRSQVDA-OBWLXNIXSA-N 50059367 (S)-2-[2-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-2-methyl-propionylamino]-N-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propyl]-3-methyl-butyramide::CHEMBL420606 Mu-type opioid receptor Cavia cutleri 4.5 ChEMBL 10.1021/jm9700530 10.7270/Q25M64T2 9258365 Bryant, SD; Guerrini, R; Salvadori, S; Bianchi, C; Tomatis, R; Attila, M; Lazarus, LH National Institute of Environmental Health Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059367 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059367&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10032916 103955208 CHEMBL420606 ZINC26575580 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50047631 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C37H52N8O10/c1-19(2)30(36(54)40-18-28(39)47)45-37(55)31(20(3)4)44-35(53)27(17-29(48)49)43-34(52)26(16-22-9-7-6-8-10-22)42-32(50)21(5)41-33(51)25(38)15-23-11-13-24(46)14-12-23/h6-14,19-21,25-27,30-31,46H,15-18,38H2,1-5H3,(H2,39,47)(H,40,54)(H,41,51)(H,42,50)(H,43,52)(H,44,53)(H,45,55)(H,48,49)/t21-,25+,26+,27+,30+,31+/m1/s1 CJAORFIPPWIGPG-QXYJMILXSA-N 50001468 (S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::3-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL317956::H-Tyr-D-Ala-Phe-Asp-Val-Val-Gly-NH2::deltorphin C Mu-type opioid receptor Cavia cutleri 420 ChEMBL 10.1021/jm9700530 10.7270/Q25M64T2 9258365 Bryant, SD; Guerrini, R; Salvadori, S; Bianchi, C; Tomatis, R; Attila, M; Lazarus, LH National Institute of Environmental Health Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001468&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10055958 103915933 CHEMBL317956 C18097 ZINC95610551 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50047633 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)C(C)(C)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C32H50N8O10/c1-15(2)24(29(48)35-14-22(34)42)39-30(49)25(16(3)4)38-28(47)21(13-23(43)44)37-31(50)32(6,7)40-26(45)17(5)36-27(46)20(33)12-18-8-10-19(41)11-9-18/h8-11,15-17,20-21,24-25,41H,12-14,33H2,1-7H3,(H2,34,42)(H,35,48)(H,36,46)(H,37,50)(H,38,47)(H,39,49)(H,40,45)(H,43,44)/t17-,20+,21+,24+,25+/m1/s1 ALLCKKBLFVTNDT-CUUBPCRASA-N 50059371 (S)-3-(2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-2-methyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL315603 Mu-type opioid receptor Cavia cutleri >10 ChEMBL 10.1021/jm9700530 10.7270/Q25M64T2 9258365 Bryant, SD; Guerrini, R; Salvadori, S; Bianchi, C; Tomatis, R; Attila, M; Lazarus, LH National Institute of Environmental Health Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059371 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059371&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10818539 103955212 CHEMBL315603 ZINC26576169 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50047641 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)C(C)(C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C38H54N8O10/c1-20(2)30(35(54)41-19-28(40)48)45-36(55)31(21(3)4)44-34(53)27(18-29(49)50)42-33(52)26(17-22-10-8-7-9-11-22)43-37(56)38(5,6)46-32(51)25(39)16-23-12-14-24(47)15-13-23/h7-15,20-21,25-27,30-31,47H,16-19,39H2,1-6H3,(H2,40,48)(H,41,54)(H,42,52)(H,43,56)(H,44,53)(H,45,55)(H,46,51)(H,49,50)/t25-,26-,27-,30-,31-/m0/s1 HZFTWHZKERFIPD-YETVUXLRSA-N 50059370 (S)-3-((S)-2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-2-methyl-propionylamino}-3-phenyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL315225 Mu-type opioid receptor Cavia cutleri >10 ChEMBL 10.1021/jm9700530 10.7270/Q25M64T2 9258365 Bryant, SD; Guerrini, R; Salvadori, S; Bianchi, C; Tomatis, R; Attila, M; Lazarus, LH National Institute of Environmental Health Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059370 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059370&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10373076 103955211 CHEMBL315225 ZINC95610446 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50045447 CC(C)[C@H](NC(=O)[C@@H](NC(=O)C1(CCCC1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C39H56N8O8/c1-22(2)31(36(53)42-21-30(41)49)45-37(54)32(23(3)4)46-38(55)39(17-9-10-18-39)47-35(52)29(20-25-11-7-6-8-12-25)44-33(50)24(5)43-34(51)28(40)19-26-13-15-27(48)16-14-26/h6-8,11-16,22-24,28-29,31-32,48H,9-10,17-21,40H2,1-5H3,(H2,41,49)(H,42,53)(H,43,51)(H,44,50)(H,45,54)(H,46,55)(H,47,52)/t24-,28-,29-,31-,32-/m0/s1 LWCRDGJQTBYXRV-OZBSPJRCSA-N 50049376 1-((S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-cyclopentanecarboxylic acid {(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-amide::CHEMBL164062 Mu-type opioid receptor Cavia cutleri 140 ChEMBL 10.1021/jm950490j 10.7270/Q2QV3KKJ 8576920 Breveglieri, A; Guerrini, R; Salvadori, S; Bianchi, C; Bryant, SD; Attila, M; Lazarus, LH University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049376 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049376&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44378547 103979730 CHEMBL164062 ZINC95606144 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50045448 CC(C)[C@H](NC(=O)[C@@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C40H58N8O8/c1-23(2)32(37(54)43-22-31(42)50)46-38(55)33(24(3)4)47-39(56)40(18-10-7-11-19-40)48-36(53)30(21-26-12-8-6-9-13-26)45-34(51)25(5)44-35(52)29(41)20-27-14-16-28(49)17-15-27/h6,8-9,12-17,23-25,29-30,32-33,49H,7,10-11,18-22,41H2,1-5H3,(H2,42,50)(H,43,54)(H,44,52)(H,45,51)(H,46,55)(H,47,56)(H,48,53)/t25-,29-,30-,32-,33-/m0/s1 FHEJNILMQNUGJA-PWUPCCMPSA-N 50049378 1-((S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-cyclohexanecarboxylic acid {(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-amide::CHEMBL405102 Mu-type opioid receptor Cavia cutleri 558 ChEMBL 10.1021/jm950490j 10.7270/Q2QV3KKJ 8576920 Breveglieri, A; Guerrini, R; Salvadori, S; Bianchi, C; Bryant, SD; Attila, M; Lazarus, LH University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049378 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049378&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44378564 103979732 CHEMBL405102 ZINC95613452 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50045449 CC(C)[C@H](NC(=O)[C@@H](NC(=O)C1(CC1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C37H52N8O8/c1-20(2)29(34(51)40-19-28(39)47)43-35(52)30(21(3)4)44-36(53)37(15-16-37)45-33(50)27(18-23-9-7-6-8-10-23)42-31(48)22(5)41-32(49)26(38)17-24-11-13-25(46)14-12-24/h6-14,20-22,26-27,29-30,46H,15-19,38H2,1-5H3,(H2,39,47)(H,40,51)(H,41,49)(H,42,48)(H,43,52)(H,44,53)(H,45,50)/t22-,26-,27-,29-,30-/m0/s1 WLTQGLAJZYXPPJ-CYPKUTQSSA-N 50049377 1-((S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-cyclopropanecarboxylic acid {(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-amide::CHEMBL349177 Mu-type opioid receptor Cavia cutleri 15 ChEMBL 10.1021/jm950490j 10.7270/Q2QV3KKJ 8576920 Breveglieri, A; Guerrini, R; Salvadori, S; Bianchi, C; Bryant, SD; Attila, M; Lazarus, LH University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049377 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049377&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44378537 103979731 CHEMBL349177 ZINC27873117 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50045450 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)C1(CCCC1)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C34H52N8O10/c1-17(2)26(31(50)37-16-24(36)44)41-32(51)27(18(3)4)40-30(49)23(15-25(45)46)39-33(52)34(12-6-7-13-34)42-28(47)19(5)38-29(48)22(35)14-20-8-10-21(43)11-9-20/h8-11,17-19,22-23,26-27,43H,6-7,12-16,35H2,1-5H3,(H2,36,44)(H,37,50)(H,38,48)(H,39,52)(H,40,49)(H,41,51)(H,42,47)(H,45,46)/t19-,22-,23-,26-,27-/m0/s1 ZSAWKUOVPFYVFS-CQGITTKDSA-N 50049381 (S)-3-[(1-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-cyclopentanecarbonyl)-amino]-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL351078 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm950490j 10.7270/Q2QV3KKJ 8576920 Breveglieri, A; Guerrini, R; Salvadori, S; Bianchi, C; Bryant, SD; Attila, M; Lazarus, LH University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049381 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049381&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44378548 103979735 CHEMBL351078 ZINC27874376 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50045451 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)C1(CC1)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C32H48N8O10/c1-15(2)24(29(48)35-14-22(34)42)39-30(49)25(16(3)4)38-28(47)21(13-23(43)44)37-31(50)32(10-11-32)40-26(45)17(5)36-27(46)20(33)12-18-6-8-19(41)9-7-18/h6-9,15-17,20-21,24-25,41H,10-14,33H2,1-5H3,(H2,34,42)(H,35,48)(H,36,46)(H,37,50)(H,38,47)(H,39,49)(H,40,45)(H,43,44)/t17-,20-,21-,24-,25-/m0/s1 WZGNAZRSYCLARN-WLYDAUPHSA-N 50049375 (S)-3-[(1-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-cyclopropanecarbonyl)-amino]-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL167836 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm950490j 10.7270/Q2QV3KKJ 8576920 Breveglieri, A; Guerrini, R; Salvadori, S; Bianchi, C; Bryant, SD; Attila, M; Lazarus, LH University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049375 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049375&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44378528 103979729 CHEMBL167836 ZINC27879047 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50045452 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)C1(CCCCC1)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C35H54N8O10/c1-18(2)27(32(51)38-17-25(37)45)42-33(52)28(19(3)4)41-31(50)24(16-26(46)47)40-34(53)35(13-7-6-8-14-35)43-29(48)20(5)39-30(49)23(36)15-21-9-11-22(44)12-10-21/h9-12,18-20,23-24,27-28,44H,6-8,13-17,36H2,1-5H3,(H2,37,45)(H,38,51)(H,39,49)(H,40,53)(H,41,50)(H,42,52)(H,43,48)(H,46,47)/t20-,23-,24-,27-,28-/m0/s1 BAPCQJRIYSCLRO-HFQUQZICSA-N 50049382 (S)-3-[(1-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-cyclohexanecarbonyl)-amino]-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL163769 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm950490j 10.7270/Q2QV3KKJ 8576920 Breveglieri, A; Guerrini, R; Salvadori, S; Bianchi, C; Bryant, SD; Attila, M; Lazarus, LH University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049382 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049382&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44378587 103979736 CHEMBL163769 ZINC27877217 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50045453 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C37H52N8O10/c1-19(2)30(36(54)40-18-28(39)47)45-37(55)31(20(3)4)44-35(53)27(17-29(48)49)43-34(52)26(16-22-9-7-6-8-10-22)42-32(50)21(5)41-33(51)25(38)15-23-11-13-24(46)14-12-23/h6-14,19-21,25-27,30-31,46H,15-18,38H2,1-5H3,(H2,39,47)(H,40,54)(H,41,51)(H,42,50)(H,43,52)(H,44,53)(H,45,55)(H,48,49)/t21-,25+,26+,27+,30+,31+/m1/s1 CJAORFIPPWIGPG-QXYJMILXSA-N 50001468 (S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::3-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL317956::H-Tyr-D-Ala-Phe-Asp-Val-Val-Gly-NH2::deltorphin C Mu-type opioid receptor Cavia cutleri 337 ChEMBL 10.1021/jm950490j 10.7270/Q2QV3KKJ 8576920 Breveglieri, A; Guerrini, R; Salvadori, S; Bianchi, C; Bryant, SD; Attila, M; Lazarus, LH University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001468&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10055958 103915933 CHEMBL317956 C18097 ZINC95610551 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50047664 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](CC(O)=O)NC(=O)C(C)(C)NC(=O)C(C)(C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C33H52N8O10/c1-16(2)24(28(48)36-15-22(35)43)39-29(49)25(17(3)4)38-27(47)21(14-23(44)45)37-30(50)32(5,6)41-31(51)33(7,8)40-26(46)20(34)13-18-9-11-19(42)12-10-18/h9-12,16-17,20-21,24-25,42H,13-15,34H2,1-8H3,(H2,35,43)(H,36,48)(H,37,50)(H,38,47)(H,39,49)(H,40,46)(H,41,51)(H,44,45)/t20-,21+,24-,25-/m0/s1 BJOKIOHBLROPGB-JQOLTRQRSA-N 50059369 (R)-3-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-2-methyl-propionylamino}-2-methyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL441889 Mu-type opioid receptor Cavia cutleri >10 ChEMBL 10.1021/jm9700530 10.7270/Q25M64T2 9258365 Bryant, SD; Guerrini, R; Salvadori, S; Bianchi, C; Tomatis, R; Attila, M; Lazarus, LH National Institute of Environmental Health Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059369&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320483 103955210 CHEMBL441889 ZINC26577014 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50045527 CN1C(CCNC(=O)c2ccccc2F)CN=C(c2ccccc2)c2ccccc12 InChI=1S/C25H24FN3O/c1-29-19(15-16-27-25(30)20-11-5-7-13-22(20)26)17-28-24(18-9-3-2-4-10-18)21-12-6-8-14-23(21)29/h2-14,19H,15-17H2,1H3,(H,27,30) SQWPOLRABKPQAP-UHFFFAOYSA-N 50049807 2-Fluoro-N-[2-(1-methyl-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)-ethyl]-benzamide::CHEMBL341529 Mu-type opioid receptor Cavia cutleri 4.7 ChEMBL 10.1021/jm950423p 10.7270/Q2222SVD 8632410 Cappelli, A; Anzini, M; Vomero, S; Menziani, MC; De Benedetti, PG; Sbacchi, M; Clarke, GD; Mennuni, L Universitá di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049807&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11795327 103980116 CHEMBL341529 ZINC13525969 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50045532 CN1C(CCNC(=O)c2cc3ccccc3[nH]2)CN=C(c2ccccc2)c2cc(Cl)ccc12 InChI=1S/C27H25ClN4O/c1-32-21(13-14-29-27(33)24-15-19-9-5-6-10-23(19)31-24)17-30-26(18-7-3-2-4-8-18)22-16-20(28)11-12-25(22)32/h2-12,15-16,21,31H,13-14,17H2,1H3,(H,29,33) BPJBSDPXZNRLRE-UHFFFAOYSA-N 50049804 1H-Indole-2-carboxylic acid [2-(7-chloro-1-methyl-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)-ethyl]-amide::CHEMBL127619 Mu-type opioid receptor Cavia cutleri >100 ChEMBL 10.1021/jm950423p 10.7270/Q2222SVD 8632410 Cappelli, A; Anzini, M; Vomero, S; Menziani, MC; De Benedetti, PG; Sbacchi, M; Clarke, GD; Mennuni, L Universitá di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049804 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049804&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10527816 103980113 CHEMBL127619 ZINC13526006 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50045535 CN1C(CCNC(=O)c2ccc(F)cc2)CN=C(c2ccccc2)c2ccccc12 InChI=1S/C25H24FN3O/c1-29-21(15-16-27-25(30)19-11-13-20(26)14-12-19)17-28-24(18-7-3-2-4-8-18)22-9-5-6-10-23(22)29/h2-14,21H,15-17H2,1H3,(H,27,30) AESATWJIMVTHFR-UHFFFAOYSA-N 50049802 4-Fluoro-N-[2-(1-methyl-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)-ethyl]-benzamide::CHEMBL127463 Mu-type opioid receptor Cavia cutleri 2.3 ChEMBL 10.1021/jm950423p 10.7270/Q2222SVD 8632410 Cappelli, A; Anzini, M; Vomero, S; Menziani, MC; De Benedetti, PG; Sbacchi, M; Clarke, GD; Mennuni, L Universitá di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049802&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10408752 103980111 CHEMBL127463 ZINC03955492 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50045537 CN1C(CCNC(=O)c2ccccc2F)CN=C(c2ccccc2)c2cc(Cl)ccc12 InChI=1S/C25H23ClFN3O/c1-30-19(13-14-28-25(31)20-9-5-6-10-22(20)27)16-29-24(17-7-3-2-4-8-17)21-15-18(26)11-12-23(21)30/h2-12,15,19H,13-14,16H2,1H3,(H,28,31) CWIDSVJPJSNWJJ-UHFFFAOYSA-N 50049809 CHEMBL126282::N-[2-(7-Chloro-1-methyl-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)-ethyl]-2-fluoro-benzamide Mu-type opioid receptor Cavia cutleri 62 ChEMBL 10.1021/jm950423p 10.7270/Q2222SVD 8632410 Cappelli, A; Anzini, M; Vomero, S; Menziani, MC; De Benedetti, PG; Sbacchi, M; Clarke, GD; Mennuni, L Universitá di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049809&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10574908 103980118 CHEMBL126282 ZINC13525988 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50045541 CN1C(CNC(=O)c2ccsc2)CN=C(c2ccccc2F)c2ccccc12 InChI=1S/C22H20FN3OS/c1-26-16(13-25-22(27)15-10-11-28-14-15)12-24-21(17-6-2-4-8-19(17)23)18-7-3-5-9-20(18)26/h2-11,14,16H,12-13H2,1H3,(H,25,27) NPGABYHTDVGGJK-UHFFFAOYSA-N 50049805 CHEMBL169703::Thiophene-3-carboxylic acid [5-(2-fluoro-phenyl)-1-methyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-ylmethyl]-amide::Tifluadom Mu-type opioid receptor Cavia cutleri 1.9 ChEMBL 10.1021/jm950423p 10.7270/Q2222SVD 8632410 Cappelli, A; Anzini, M; Vomero, S; Menziani, MC; De Benedetti, PG; Sbacchi, M; Clarke, GD; Mennuni, L Universitá di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049805&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 115208 103980114 CHEMBL169703 1667 C11797 ZINC01532369 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50045546 CN1C(CCNC(=O)c2cccs2)CN=C(c2ccccc2)c2ccccc12 InChI=1S/C23H23N3OS/c1-26-18(13-14-24-23(27)21-12-7-15-28-21)16-25-22(17-8-3-2-4-9-17)19-10-5-6-11-20(19)26/h2-12,15,18H,13-14,16H2,1H3,(H,24,27) PYCHFYLMMMZMSJ-UHFFFAOYSA-N 50049806 CHEMBL127969::Thiophene-2-carboxylic acid [2-(1-methyl-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)-ethyl]-amide Mu-type opioid receptor Cavia cutleri 6.4 ChEMBL 10.1021/jm950423p 10.7270/Q2222SVD 8632410 Cappelli, A; Anzini, M; Vomero, S; Menziani, MC; De Benedetti, PG; Sbacchi, M; Clarke, GD; Mennuni, L Universitá di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049806&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10430432 103980115 CHEMBL127969 ZINC03955493 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50045547 CN1C(CCNC(=O)c2ccc(F)cc2)CN=C(c2ccccc2)c2cc(Cl)ccc12 InChI=1S/C25H23ClFN3O/c1-30-21(13-14-28-25(31)18-7-10-20(27)11-8-18)16-29-24(17-5-3-2-4-6-17)22-15-19(26)9-12-23(22)30/h2-12,15,21H,13-14,16H2,1H3,(H,28,31) FLRKSGDCJCTWFD-UHFFFAOYSA-N 50049808 CHEMBL127968::N-[2-(7-Chloro-1-methyl-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)-ethyl]-4-fluoro-benzamide Mu-type opioid receptor Cavia cutleri 53 ChEMBL 10.1021/jm950423p 10.7270/Q2222SVD 8632410 Cappelli, A; Anzini, M; Vomero, S; Menziani, MC; De Benedetti, PG; Sbacchi, M; Clarke, GD; Mennuni, L Universitá di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049808&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10599027 103980117 CHEMBL127968 ZINC13525993 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50045548 CN1C(CCNC(=O)c2cccs2)CN=C(c2ccccc2)c2cc(Cl)ccc12 InChI=1S/C23H22ClN3OS/c1-27-18(11-12-25-23(28)21-8-5-13-29-21)15-26-22(16-6-3-2-4-7-16)19-14-17(24)9-10-20(19)27/h2-10,13-14,18H,11-12,15H2,1H3,(H,25,28) JEZGMXQLYTYHBX-UHFFFAOYSA-N 50049803 CHEMBL124015::Thiophene-2-carboxylic acid [2-(7-chloro-1-methyl-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)-ethyl]-amide Mu-type opioid receptor Cavia cutleri 69 ChEMBL 10.1021/jm950423p 10.7270/Q2222SVD 8632410 Cappelli, A; Anzini, M; Vomero, S; Menziani, MC; De Benedetti, PG; Sbacchi, M; Clarke, GD; Mennuni, L Universitá di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049803&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10645976 103980112 CHEMBL124015 ZINC13525981 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50045552 CN1C(CCNC(=O)c2ccc(Cl)cc2)CN=C(c2ccccc2)c2cc(Cl)ccc12 InChI=1S/C25H23Cl2N3O/c1-30-21(13-14-28-25(31)18-7-9-19(26)10-8-18)16-29-24(17-5-3-2-4-6-17)22-15-20(27)11-12-23(22)30/h2-12,15,21H,13-14,16H2,1H3,(H,28,31) JOQGMEWJGYYNAI-UHFFFAOYSA-N 50049801 4-Chloro-N-[2-(7-chloro-1-methyl-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)-ethyl]-benzamide::CHEMBL340001 Mu-type opioid receptor Cavia cutleri >100 ChEMBL 10.1021/jm950423p 10.7270/Q2222SVD 8632410 Cappelli, A; Anzini, M; Vomero, S; Menziani, MC; De Benedetti, PG; Sbacchi, M; Clarke, GD; Mennuni, L Universitá di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049801 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049801&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10718445 103980110 CHEMBL340001 ZINC13525999 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50052247 C[C@H]1CN(C\C=C\c2ccccc2Cl)CC[C@@]1(C)c1cccc(O)c1 InChI=1S/C22H26ClNO/c1-17-16-24(13-6-8-18-7-3-4-11-21(18)23)14-12-22(17,2)19-9-5-10-20(25)15-19/h3-11,15,17,25H,12-14,16H2,1-2H3/b8-6+/t17-,22+/m0/s1 RRGWRLNJBLFYOG-KISUKSLOSA-N 50064518 3-{(3R,4R)-1-[(E)-3-(2-Chloro-phenyl)-allyl]-3,4-dimethyl-piperidin-4-yl}-phenol::3-{1-[3-(2-Chloro-phenyl)-allyl]-3,4-dimethyl-piperidin-4-yl}-phenol::CHEMBL50594::RTI-5989-23 Mu-type opioid receptor Cavia cutleri 0.026000 ChEMBL 10.1021/jm980063g 10.7270/Q2K35SSN 9599247 Thomas, JB; Mascarella, SW; Rothman, RB; Partilla, JS; Xu, H; McCullough, KB; Dersch, CM; Cantrell, BE; Zimmerman, DM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064518&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10808145 103959535 CHEMBL50594 ZINC13779626 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50052251 C[C@H]1CN(CC[C@H](O)C2CCCCC2)CC[C@@]1(C)c1cccc(O)c1 InChI=1S/C22H35NO2/c1-17-16-23(13-11-21(25)18-7-4-3-5-8-18)14-12-22(17,2)19-9-6-10-20(24)15-19/h6,9-10,15,17-18,21,24-25H,3-5,7-8,11-14,16H2,1-2H3/t17-,21-,22+/m0/s1 LVVHEFJXPXAUDD-BULFRSBZSA-N 50045775 (3R,4R)3-[1-(3-Cyclohexyl-3-hydroxy-propyl)-3,4-dimethyl-piperidin-4-yl]-phenol::3-((3R,4R)-1-((S)-3-cyclohexyl-3-hydroxypropyl)-3,4-dimethylpiperidin-4-yl)phenol::3-[(3R,4R)-1-((S)-3-Cyclohexyl-3-hydroxy-propyl)-3,4-dimethyl-piperidin-4-yl]-phenol::3-[1-(3-Cyclohexyl-3-hydroxy-propyl)-3,4-dimethyl-piperidin-4-yl]-phenol::CHEMBL300662::LY-255582 Mu-type opioid receptor Cavia cutleri 0.021000 ChEMBL 10.1021/jm980063g 10.7270/Q2K35SSN 9599247 Thomas, JB; Mascarella, SW; Rothman, RB; Partilla, JS; Xu, H; McCullough, KB; Dersch, CM; Cantrell, BE; Zimmerman, DM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045775&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9906198 103976648 CHEMBL300662 C03491 ZINC03783617 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50052258 C[C@H]1CN(C\C=C\c2ccccc2C)CC[C@@]1(C)c1cccc(O)c1 InChI=1S/C23H29NO/c1-18-8-4-5-9-20(18)10-7-14-24-15-13-23(3,19(2)17-24)21-11-6-12-22(25)16-21/h4-12,16,19,25H,13-15,17H2,1-3H3/b10-7+/t19-,23+/m0/s1 FJFLDQXXCJUUBR-XECBNOGISA-N 50064515 3-[(3R,4R)-3,4-Dimethyl-1-((E)-3-o-tolyl-allyl)-piperidin-4-yl]-phenol::3-[(3R,4R)-3,4-Dimethyl-1-(3-o-tolyl-allyl)-piperidin-4-yl]-phenol::3-[3,4-Dimethyl-1-(3-o-tolyl-allyl)-piperidin-4-yl]-phenol::CHEMBL52451::RTI-5989-25 Mu-type opioid receptor Cavia cutleri 0.013000 ChEMBL 10.1021/jm980063g 10.7270/Q2K35SSN 9599247 Thomas, JB; Mascarella, SW; Rothman, RB; Partilla, JS; Xu, H; McCullough, KB; Dersch, CM; Cantrell, BE; Zimmerman, DM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064515 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064515&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9840689 103959532 CHEMBL52451 ZINC13532660 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50052263 C[C@H]1CN(C\C=C\c2ccccc2)CC[C@@]1(C)c1cccc(O)c1 InChI=1S/C22H27NO/c1-18-17-23(14-7-10-19-8-4-3-5-9-19)15-13-22(18,2)20-11-6-12-21(24)16-20/h3-12,16,18,24H,13-15,17H2,1-2H3/b10-7+/t18-,22+/m0/s1 SUIRCGLIUIROIR-SRHFXGPLSA-N 50064521 3-[(3R,4R)-3,4-Dimethyl-1-((E)-3-phenyl-allyl)-piperidin-4-yl]-phenol::3-[3,4-Dimethyl-1-(3-phenyl-allyl)-piperidin-4-yl]-phenol::CHEMBL51838 Mu-type opioid receptor Cavia cutleri 0.039000 ChEMBL 10.1021/jm980063g 10.7270/Q2K35SSN 9599247 Thomas, JB; Mascarella, SW; Rothman, RB; Partilla, JS; Xu, H; McCullough, KB; Dersch, CM; Cantrell, BE; Zimmerman, DM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064521 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064521&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9973387 103959538 CHEMBL51838 ZINC13779625 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50052264 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1 DQCKKXVULJGBQN-XFWGSAIBSA-N 60212 (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::MLS000069607::NALTREXONE HYDROCHLORIDE::SMR000058767::US10988481, Compound NTX::US9107954, naltrexone::cid_5485201 Mu-type opioid receptor Cavia cutleri 0.930000 ChEMBL 10.1021/jm980063g 10.7270/Q2K35SSN 9599247 Thomas, JB; Mascarella, SW; Rothman, RB; Partilla, JS; Xu, H; McCullough, KB; Dersch, CM; Cantrell, BE; Zimmerman, DM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60212&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5360515 252639834 DB00704 C07253 ZINC00001773 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50051264 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H]1CCCNC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(=O)N1)NC(=O)CNC(=O)[C@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C76H124N22O16/c1-7-45(6)62(72(111)92-53(25-17-35-86-76(82)83)73(112)98-36-18-26-59(98)71(110)91-51(21-11-13-31-77)66(105)95-56(38-44(4)5)68(107)93-54(74(113)114)22-12-14-32-78)97-67(106)52(24-16-34-85-75(80)81)90-65(104)50-23-15-33-84-64(103)55(37-43(2)3)94-69(108)57(40-46-19-9-8-10-20-46)96-70(109)58(41-60(100)88-50)89-61(101)42-87-63(102)49(79)39-47-27-29-48(99)30-28-47/h8-10,19-20,27-30,43-45,49-59,62,99H,7,11-18,21-26,31-42,77-79H2,1-6H3,(H,84,103)(H,87,102)(H,88,100)(H,89,101)(H,90,104)(H,91,110)(H,92,111)(H,93,107)(H,94,108)(H,95,105)(H,96,109)(H,97,106)(H,113,114)(H4,80,81,85)(H4,82,83,86)/t45-,49+,50+,51-,52-,53-,54-,55-,56-,57+,58-,59-,62-/m0/s1 VBDHBWCUISGKHP-RQHQCWBJSA-N 50057390 Analog of Dynorphin A::CHEMBL2370832 Mu-type opioid receptor Cavia cutleri 320 ChEMBL 10.1021/jm960753p 10.7270/Q2BG2N3H 9111295 Arttamangkul, S; Ishmael, JE; Murray, TF; Grandy, DK; DeLander, GE; Kieffer, BL; Aldrich, JV Oregon State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057390 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057390&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73348535 103953444 CHEMBL2370832 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50051265 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H]1CCNC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(=O)N1)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C75H122N22O16/c1-7-44(6)61(71(110)91-52(23-16-33-85-75(81)82)72(111)97-35-17-24-58(97)70(109)90-49(20-11-13-30-76)64(103)94-55(37-43(4)5)67(106)92-53(73(112)113)21-12-14-31-77)96-66(105)50(22-15-32-84-74(79)80)89-65(104)51-29-34-83-63(102)54(36-42(2)3)93-68(107)56(39-45-18-9-8-10-19-45)95-69(108)57(40-59(99)87-51)88-60(100)41-86-62(101)48(78)38-46-25-27-47(98)28-26-46/h8-10,18-19,25-28,42-44,48-58,61,98H,7,11-17,20-24,29-41,76-78H2,1-6H3,(H,83,102)(H,86,101)(H,87,99)(H,88,100)(H,89,104)(H,90,109)(H,91,110)(H,92,106)(H,93,107)(H,94,103)(H,95,108)(H,96,105)(H,112,113)(H4,79,80,84)(H4,81,82,85)/t44-,48-,49-,50-,51+,52-,53-,54-,55-,56+,57-,58-,61-/m0/s1 UUDXDCXVXVLBMJ-SYNJULTKSA-N 50057384 Analog of Dynorphin A::CHEMBL2370831 Mu-type opioid receptor Cavia cutleri 210 ChEMBL 10.1021/jm960753p 10.7270/Q2BG2N3H 9111295 Arttamangkul, S; Ishmael, JE; Murray, TF; Grandy, DK; DeLander, GE; Kieffer, BL; Aldrich, JV Oregon State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057384 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057384&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73348534 103953438 CHEMBL2370831 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50051266 CC[C@H](C)[C@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(=O)N[C@@H](CCCNC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C72H115N19O16/c1-7-43(6)60-69(104)78-31-16-23-50(70(105)91-33-17-24-56(91)68(103)85-48(20-11-13-29-73)62(97)87-52(34-41(2)3)64(99)86-51(71(106)107)21-12-14-30-74)82-57(93)38-55(67(102)84-49(63(98)90-60)22-15-32-79-72(76)77)89-65(100)53(35-42(4)5)88-66(101)54(37-44-18-9-8-10-19-44)83-59(95)40-80-58(94)39-81-61(96)47(75)36-45-25-27-46(92)28-26-45/h8-10,18-19,25-28,41-43,47-56,60,92H,7,11-17,20-24,29-40,73-75H2,1-6H3,(H,78,104)(H,80,94)(H,81,96)(H,82,93)(H,83,95)(H,84,102)(H,85,103)(H,86,99)(H,87,97)(H,88,101)(H,89,100)(H,90,98)(H,106,107)(H4,76,77,79)/t43-,47-,48-,49-,50-,51-,52-,53-,54-,55-,56-,60+/m0/s1 PCNNSTOCKCFRQQ-AXGUWQFGSA-N 50057391 Analog of Dynorphin A::CHEMBL412413 Mu-type opioid receptor Cavia cutleri 3.2 ChEMBL 10.1021/jm960753p 10.7270/Q2BG2N3H 9111295 Arttamangkul, S; Ishmael, JE; Murray, TF; Grandy, DK; DeLander, GE; Kieffer, BL; Aldrich, JV Oregon State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057391 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057391&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44273019 103953445 CHEMBL412413 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50051268 CC[C@H](C)[C@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(=O)N[C@@H](CCNC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C71H113N19O16/c1-7-42(6)59-68(103)77-31-27-49(69(104)90-32-16-22-55(90)67(102)84-47(19-11-13-28-72)61(96)86-51(33-40(2)3)63(98)85-50(70(105)106)20-12-14-29-73)81-56(92)37-54(66(101)83-48(62(97)89-59)21-15-30-78-71(75)76)88-64(99)52(34-41(4)5)87-65(100)53(36-43-17-9-8-10-18-43)82-58(94)39-79-57(93)38-80-60(95)46(74)35-44-23-25-45(91)26-24-44/h8-10,17-18,23-26,40-42,46-55,59,91H,7,11-16,19-22,27-39,72-74H2,1-6H3,(H,77,103)(H,79,93)(H,80,95)(H,81,92)(H,82,94)(H,83,101)(H,84,102)(H,85,98)(H,86,96)(H,87,100)(H,88,99)(H,89,97)(H,105,106)(H4,75,76,78)/t42-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,59+/m0/s1 ATJBGHAJWAUIGB-HUCZMNRHSA-N 50057386 Analog of Dynorphin A::CHEMBL263366 Mu-type opioid receptor Cavia cutleri 4.8 ChEMBL 10.1021/jm960753p 10.7270/Q2BG2N3H 9111295 Arttamangkul, S; Ishmael, JE; Murray, TF; Grandy, DK; DeLander, GE; Kieffer, BL; Aldrich, JV Oregon State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057386 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057386&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44273020 103953440 CHEMBL263366 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50051269 CC[C@H](C)[C@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(=O)N[C@@H](CNC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C70H111N19O16/c1-7-41(6)58-67(102)78-36-53(68(103)89-30-16-22-54(89)66(101)83-46(19-11-13-27-71)60(95)85-49(31-39(2)3)62(97)84-48(69(104)105)20-12-14-28-72)81-55(91)35-52(65(100)82-47(61(96)88-58)21-15-29-76-70(74)75)87-63(98)50(32-40(4)5)86-64(99)51(34-42-17-9-8-10-18-42)80-57(93)38-77-56(92)37-79-59(94)45(73)33-43-23-25-44(90)26-24-43/h8-10,17-18,23-26,39-41,45-54,58,90H,7,11-16,19-22,27-38,71-73H2,1-6H3,(H,77,92)(H,78,102)(H,79,94)(H,80,93)(H,81,91)(H,82,100)(H,83,101)(H,84,97)(H,85,95)(H,86,99)(H,87,98)(H,88,96)(H,104,105)(H4,74,75,76)/t41-,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,58+/m0/s1 HVGDKOWJKJGQMG-QUHQWUQPSA-N 50057393 Analog of Dynorphin A::CHEMBL264481 Mu-type opioid receptor Cavia cutleri 4.4 ChEMBL 10.1021/jm960753p 10.7270/Q2BG2N3H 9111295 Arttamangkul, S; Ishmael, JE; Murray, TF; Grandy, DK; DeLander, GE; Kieffer, BL; Aldrich, JV Oregon State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057393&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44273021 103953447 CHEMBL264481 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50051270 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NC[C@@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C70H113N19O17/c1-7-41(6)58(67(103)79-36-46(74)68(104)89-30-16-22-54(89)66(102)83-47(19-11-13-27-71)60(96)85-50(31-39(2)3)62(98)84-49(69(105)106)20-12-14-28-72)88-61(97)48(21-15-29-77-70(75)76)82-65(101)53(35-57(93)94)87-63(99)51(32-40(4)5)86-64(100)52(34-42-17-9-8-10-18-42)81-56(92)38-78-55(91)37-80-59(95)45(73)33-43-23-25-44(90)26-24-43/h8-10,17-18,23-26,39-41,45-54,58,90H,7,11-16,19-22,27-38,71-74H2,1-6H3,(H,78,91)(H,79,103)(H,80,95)(H,81,92)(H,82,101)(H,83,102)(H,84,98)(H,85,96)(H,86,100)(H,87,99)(H,88,97)(H,93,94)(H,105,106)(H4,75,76,77)/t41-,45-,46+,47-,48-,49-,50-,51-,52-,53-,54-,58-/m0/s1 PCCFTXSJJFHTKK-ONRJLGDDSA-N 50057389 Analog of Dynorphin A::CHEMBL408024 Mu-type opioid receptor Cavia cutleri 1.5 ChEMBL 10.1021/jm960753p 10.7270/Q2BG2N3H 9111295 Arttamangkul, S; Ishmael, JE; Murray, TF; Grandy, DK; DeLander, GE; Kieffer, BL; Aldrich, JV Oregon State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057389 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057389&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44273082 103953443 CHEMBL408024 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50051271 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C73H119N21O17/c1-7-43(6)60(69(108)88-50(23-16-32-82-73(79)80)70(109)94-33-17-24-56(94)68(107)87-48(20-11-13-29-74)62(101)90-52(34-41(2)3)64(103)89-51(71(110)111)21-12-14-30-75)93-63(102)49(22-15-31-81-72(77)78)86-67(106)55(38-59(98)99)92-65(104)53(35-42(4)5)91-66(105)54(37-44-18-9-8-10-19-44)85-58(97)40-83-57(96)39-84-61(100)47(76)36-45-25-27-46(95)28-26-45/h8-10,18-19,25-28,41-43,47-56,60,95H,7,11-17,20-24,29-40,74-76H2,1-6H3,(H,83,96)(H,84,100)(H,85,97)(H,86,106)(H,87,107)(H,88,108)(H,89,103)(H,90,101)(H,91,105)(H,92,104)(H,93,102)(H,98,99)(H,110,111)(H4,77,78,81)(H4,79,80,82)/t43-,47-,48-,49-,50-,51-,52-,53-,54-,55-,56-,60-/m0/s1 MHZKLGWFMJFBSS-ODMWZFNZSA-N 50057380 Analog of Dynorphin A::CHEMBL408360 Mu-type opioid receptor Cavia cutleri 1.2 ChEMBL 10.1021/jm960753p 10.7270/Q2BG2N3H 9111295 Arttamangkul, S; Ishmael, JE; Murray, TF; Grandy, DK; DeLander, GE; Kieffer, BL; Aldrich, JV Oregon State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057380 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057380&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44273081 103953434 CHEMBL408360 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50051279 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H]1CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(=O)N1)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C74H120N22O16/c1-7-43(6)60(70(109)90-50(23-16-32-83-74(80)81)71(110)96-33-17-24-57(96)69(108)89-48(20-11-13-29-75)63(102)93-53(35-42(4)5)65(104)91-51(72(111)112)21-12-14-30-76)95-64(103)49(22-15-31-82-73(78)79)88-68(107)56-39-84-62(101)52(34-41(2)3)92-66(105)54(37-44-18-9-8-10-19-44)94-67(106)55(38-58(98)87-56)86-59(99)40-85-61(100)47(77)36-45-25-27-46(97)28-26-45/h8-10,18-19,25-28,41-43,47-57,60,97H,7,11-17,20-24,29-40,75-77H2,1-6H3,(H,84,101)(H,85,100)(H,86,99)(H,87,98)(H,88,107)(H,89,108)(H,90,109)(H,91,104)(H,92,105)(H,93,102)(H,94,106)(H,95,103)(H,111,112)(H4,78,79,82)(H4,80,81,83)/t43-,47-,48-,49-,50-,51-,52-,53-,54+,55-,56+,57-,60-/m0/s1 PTSYWCRMWFGUAU-GPSGTAMUSA-N 50057388 Analog of Dynorphin A::CHEMBL2370877 Mu-type opioid receptor Cavia cutleri 910 ChEMBL 10.1021/jm960753p 10.7270/Q2BG2N3H 9111295 Arttamangkul, S; Ishmael, JE; Murray, TF; Grandy, DK; DeLander, GE; Kieffer, BL; Aldrich, JV Oregon State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057388 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057388&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73351611 103953442 CHEMBL2370877 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50051281 CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H]1CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CC(=O)N1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C70H113N25O16/c1-39(2)32-49(61(104)92-48(67(110)111)17-7-9-27-72)93-60(103)45(16-6-8-26-71)90-65(108)53-21-13-31-95(53)66(109)47(20-12-30-82-70(78)79)91-64(107)52-36-84-58(101)44(18-10-28-80-68(74)75)88-59(102)46(19-11-29-81-69(76)77)89-63(106)51(35-54(97)87-52)94-62(105)50(34-40-14-4-3-5-15-40)86-56(99)38-83-55(98)37-85-57(100)43(73)33-41-22-24-42(96)25-23-41/h3-5,14-15,22-25,39,43-53,96H,6-13,16-21,26-38,71-73H2,1-2H3,(H,83,98)(H,84,101)(H,85,100)(H,86,99)(H,87,97)(H,88,102)(H,89,106)(H,90,108)(H,91,107)(H,92,104)(H,93,103)(H,94,105)(H,110,111)(H4,74,75,80)(H4,76,77,81)(H4,78,79,82)/t43-,44-,45-,46+,47-,48-,49-,50-,51+,52+,53-/m0/s1 HQGLMUPOASCLOC-GAFYAZJLSA-N 50057387 Analog of Dynorphin A::CHEMBL412364 Mu-type opioid receptor Cavia cutleri 75 ChEMBL 10.1021/jm960753p 10.7270/Q2BG2N3H 9111295 Arttamangkul, S; Ishmael, JE; Murray, TF; Grandy, DK; DeLander, GE; Kieffer, BL; Aldrich, JV Oregon State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057387 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057387&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44273050 103953441 CHEMBL412364 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50051283 CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H]1CCCNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CC(=O)N1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C72H117N25O16/c1-41(2)35-52(64(107)94-51(69(112)113)18-7-9-29-74)95-63(106)48(17-6-8-28-73)92-67(110)55-23-14-34-97(55)68(111)50(22-13-33-85-72(80)81)93-61(104)47-20-10-30-82-60(103)46(19-11-31-83-70(76)77)90-62(105)49(21-12-32-84-71(78)79)91-66(109)54(38-56(99)88-47)96-65(108)53(37-42-15-4-3-5-16-42)89-58(101)40-86-57(100)39-87-59(102)45(75)36-43-24-26-44(98)27-25-43/h3-5,15-16,24-27,41,45-55,98H,6-14,17-23,28-40,73-75H2,1-2H3,(H,82,103)(H,86,100)(H,87,102)(H,88,99)(H,89,101)(H,90,105)(H,91,109)(H,92,110)(H,93,104)(H,94,107)(H,95,106)(H,96,108)(H,112,113)(H4,76,77,83)(H4,78,79,84)(H4,80,81,85)/t45-,46-,47+,48-,49+,50-,51-,52-,53-,54+,55-/m0/s1 SXKHDZYFPQAXJB-FIKYEUOGSA-N 50057381 Analog of Dynorphin A::CHEMBL414921 Mu-type opioid receptor Cavia cutleri 62 ChEMBL 10.1021/jm960753p 10.7270/Q2BG2N3H 9111295 Arttamangkul, S; Ishmael, JE; Murray, TF; Grandy, DK; DeLander, GE; Kieffer, BL; Aldrich, JV Oregon State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057381 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057381&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44273049 103953435 CHEMBL414921 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50051285 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C73H120N24O17/c1-5-42(4)59(68(111)92-50(23-15-33-85-73(81)82)69(112)97-34-16-24-55(97)67(110)91-47(19-9-11-29-74)62(105)94-52(35-41(2)3)64(107)93-51(70(113)114)20-10-12-30-75)96-63(106)49(22-14-32-84-72(79)80)89-61(104)48(21-13-31-83-71(77)78)90-66(109)54(38-58(101)102)95-65(108)53(37-43-17-7-6-8-18-43)88-57(100)40-86-56(99)39-87-60(103)46(76)36-44-25-27-45(98)28-26-44/h6-8,17-18,25-28,41-42,46-55,59,98H,5,9-16,19-24,29-40,74-76H2,1-4H3,(H,86,99)(H,87,103)(H,88,100)(H,89,104)(H,90,109)(H,91,110)(H,92,111)(H,93,107)(H,94,105)(H,95,108)(H,96,106)(H,101,102)(H,113,114)(H4,77,78,83)(H4,79,80,84)(H4,81,82,85)/t42-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,59-/m0/s1 GBWRFRNRTHKYGC-WMMJVZBNSA-N 50057385 Analog of Dynorphin A::CHEMBL406899 Mu-type opioid receptor Cavia cutleri 6.1 ChEMBL 10.1021/jm960753p 10.7270/Q2BG2N3H 9111295 Arttamangkul, S; Ishmael, JE; Murray, TF; Grandy, DK; DeLander, GE; Kieffer, BL; Aldrich, JV Oregon State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057385 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057385&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44273048 103953439 CHEMBL406899 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50051288 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C77H128N24O17/c1-7-45(6)62(72(115)95-53(25-17-35-89-77(85)86)73(116)101-36-18-26-59(101)71(114)94-50(21-11-13-31-78)65(108)97-56(38-44(4)5)68(111)96-54(74(117)118)22-12-14-32-79)100-66(109)52(24-16-34-88-76(83)84)92-64(107)51(23-15-33-87-75(81)82)93-67(110)55(37-43(2)3)98-69(112)57(40-46-19-9-8-10-20-46)99-70(113)58(41-61(104)105)91-60(103)42-90-63(106)49(80)39-47-27-29-48(102)30-28-47/h8-10,19-20,27-30,43-45,49-59,62,102H,7,11-18,21-26,31-42,78-80H2,1-6H3,(H,90,106)(H,91,103)(H,92,107)(H,93,110)(H,94,114)(H,95,115)(H,96,111)(H,97,108)(H,98,112)(H,99,113)(H,100,109)(H,104,105)(H,117,118)(H4,81,82,87)(H4,83,84,88)(H4,85,86,89)/t45-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-/m0/s1 PHLGOCGKJRRHBR-LMVWZCQBSA-N 50057383 Analog of Dynorphin A::CHEMBL2370861 Mu-type opioid receptor Cavia cutleri 180 ChEMBL 10.1021/jm960753p 10.7270/Q2BG2N3H 9111295 Arttamangkul, S; Ishmael, JE; Murray, TF; Grandy, DK; DeLander, GE; Kieffer, BL; Aldrich, JV Oregon State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057383 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057383&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73356166 103953437 CHEMBL2370861 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50051295 CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](N)CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C70H115N25O17/c1-39(2)32-50(62(106)92-49(67(111)112)17-7-9-27-72)93-61(105)46(16-6-8-26-71)90-65(109)53-21-13-31-95(53)66(110)48(20-12-30-83-70(79)80)91-58(102)44(74)36-85-59(103)45(18-10-28-81-68(75)76)88-60(104)47(19-11-29-82-69(77)78)89-64(108)52(35-56(99)100)94-63(107)51(34-40-14-4-3-5-15-40)87-55(98)38-84-54(97)37-86-57(101)43(73)33-41-22-24-42(96)25-23-41/h3-5,14-15,22-25,39,43-53,96H,6-13,16-21,26-38,71-74H2,1-2H3,(H,84,97)(H,85,103)(H,86,101)(H,87,98)(H,88,104)(H,89,108)(H,90,109)(H,91,102)(H,92,106)(H,93,105)(H,94,107)(H,99,100)(H,111,112)(H4,75,76,81)(H4,77,78,82)(H4,79,80,83)/t43-,44+,45-,46-,47-,48-,49-,50-,51-,52-,53-/m0/s1 IJNUNIRFWZVQTK-RAIDLXLHSA-N 50057379 Analog of Dynorphin A::CHEMBL407076 Mu-type opioid receptor Cavia cutleri 8.3 ChEMBL 10.1021/jm960753p 10.7270/Q2BG2N3H 9111295 Arttamangkul, S; Ishmael, JE; Murray, TF; Grandy, DK; DeLander, GE; Kieffer, BL; Aldrich, JV Oregon State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057379 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057379&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44272934 103953433 CHEMBL407076 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50051300 CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H]1CCNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CC(=O)N1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C71H115N25O16/c1-40(2)34-51(63(106)93-50(68(111)112)17-7-9-28-73)94-61(104)46(16-6-8-27-72)91-66(109)54-21-13-33-96(54)67(110)49(20-12-31-84-71(79)80)92-62(105)48-26-32-81-59(102)45(18-10-29-82-69(75)76)89-60(103)47(19-11-30-83-70(77)78)90-65(108)53(37-55(98)87-48)95-64(107)52(36-41-14-4-3-5-15-41)88-57(100)39-85-56(99)38-86-58(101)44(74)35-42-22-24-43(97)25-23-42/h3-5,14-15,22-25,40,44-54,97H,6-13,16-21,26-39,72-74H2,1-2H3,(H,81,102)(H,85,99)(H,86,101)(H,87,98)(H,88,100)(H,89,103)(H,90,108)(H,91,109)(H,92,105)(H,93,106)(H,94,104)(H,95,107)(H,111,112)(H4,75,76,82)(H4,77,78,83)(H4,79,80,84)/t44-,45-,46-,47+,48+,49-,50-,51-,52-,53+,54-/m0/s1 RWOANWRJDINCAV-MIQZKGAQSA-N 50057382 Analog of Dynorphin A::CHEMBL386618 Mu-type opioid receptor Cavia cutleri 40 ChEMBL 10.1021/jm960753p 10.7270/Q2BG2N3H 9111295 Arttamangkul, S; Ishmael, JE; Murray, TF; Grandy, DK; DeLander, GE; Kieffer, BL; Aldrich, JV Oregon State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057382 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057382&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44272933 103953436 CHEMBL386618 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50051302 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C75H123N21O17/c1-8-44(6)61(71(110)90-52(24-17-33-84-75(81)82)72(111)96-34-18-25-58(96)70(109)89-50(21-12-14-30-76)65(104)93-55(36-43(4)5)67(106)91-53(73(112)113)22-13-15-31-77)95-66(105)51(23-16-32-83-74(79)80)88-62(101)45(7)40-85-64(103)54(35-42(2)3)92-68(107)56(38-46-19-10-9-11-20-46)94-69(108)57(39-60(99)100)87-59(98)41-86-63(102)49(78)37-47-26-28-48(97)29-27-47/h9-11,19-20,26-29,42-45,49-58,61,97H,8,12-18,21-25,30-41,76-78H2,1-7H3,(H,85,103)(H,86,102)(H,87,98)(H,88,101)(H,89,109)(H,90,110)(H,91,106)(H,92,107)(H,93,104)(H,94,108)(H,95,105)(H,99,100)(H,112,113)(H4,79,80,83)(H4,81,82,84)/t44-,45+,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,61-/m0/s1 MVPSEFZFBNTCMV-GKRIIVFHSA-N 50057392 Analog of Dynorphin A::CHEMBL2370887 Mu-type opioid receptor Cavia cutleri 100 ChEMBL 10.1021/jm960753p 10.7270/Q2BG2N3H 9111295 Arttamangkul, S; Ishmael, JE; Murray, TF; Grandy, DK; DeLander, GE; Kieffer, BL; Aldrich, JV Oregon State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057392 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057392&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73353093 103953446 CHEMBL2370887 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50051305 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C75H126N24O15/c1-7-45(6)61(70(111)94-53(25-17-35-87-75(83)84)71(112)99-36-18-26-58(99)69(110)93-50(21-11-13-31-76)64(105)96-56(38-44(4)5)67(108)95-54(72(113)114)22-12-14-32-77)98-65(106)52(24-16-34-86-74(81)82)91-63(104)51(23-15-33-85-73(79)80)92-66(107)55(37-43(2)3)97-68(109)57(40-46-19-9-8-10-20-46)90-60(102)42-88-59(101)41-89-62(103)49(78)39-47-27-29-48(100)30-28-47/h8-10,19-20,27-30,43-45,49-58,61,100H,7,11-18,21-26,31-42,76-78H2,1-6H3,(H,88,101)(H,89,103)(H,90,102)(H,91,104)(H,92,107)(H,93,110)(H,94,111)(H,95,108)(H,96,105)(H,97,109)(H,98,106)(H,113,114)(H4,79,80,85)(H4,81,82,86)(H4,83,84,87)/t45-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,61-/m0/s1 OVVIBUHLQIYUEU-IWIISZHXSA-N 224024 BDBM50241435::Dynorphin A (1-13)::YGGFLRRXRPKLK Mu-type opioid receptor Cavia cutleri 0.92 ChEMBL 10.1021/jm960753p 10.7270/Q2BG2N3H 9111295 Arttamangkul, S; Ishmael, JE; Murray, TF; Grandy, DK; DeLander, GE; Kieffer, BL; Aldrich, JV Oregon State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=224024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=224024&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25075996 374884564 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50050489 CCN(CC)C(=O)c1ccc(cc1)[C@H](N1C[C@H](C)N(CC=C)C[C@H]1C)c1cccc(OC)c1 InChI=1S/C28H39N3O2/c1-7-17-30-19-22(5)31(20-21(30)4)27(25-11-10-12-26(18-25)33-6)23-13-15-24(16-14-23)28(32)29(8-2)9-3/h7,10-16,18,21-22,27H,1,8-9,17,19-20H2,2-6H3/t21-,22+,27-/m0/s1 KQWVAUSXZDRQPZ-XXAUWVGASA-N 50039024 4-[(S)-((2R,5S)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::CHEMBL65648::cid_16219954 Mu-type opioid receptor Cavia cutleri 1517 ChEMBL 10.1021/jm960319n 10.7270/Q2F190DS 9057856 Calderon, SN; Rice, KC; Rothman, RB; Porreca, F; Flippen-Anderson, JL; Kayakiri, H; Xu, H; Becketts, K; Smith, LE; Bilsky, EJ; Davis, P; Horvath, R National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039024&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 398116 103946287 CHEMBL65648 ZINC19371672 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50050490 CCN(CC)C(=O)c1ccc(cc1)C(N1C[C@@H](C)N(CC=C)C[C@@H]1C)c1ccccc1 InChI=1S/C27H37N3O/c1-6-18-29-19-22(5)30(20-21(29)4)26(23-12-10-9-11-13-23)24-14-16-25(17-15-24)27(31)28(7-2)8-3/h6,9-17,21-22,26H,1,7-8,18-20H2,2-5H3/t21-,22+,26?/m1/s1 WGIDFDFAOQVAHY-SGNGHUOJSA-N 50056543 4-[((1R,2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-phenyl-methyl]-N,N-diethyl-benzamide::4-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-phenyl-methyl]-N,N-diethyl-benzamide::4-[(S)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-phenyl-methyl]-N,N-diethyl-benzamide::CHEMBL153648 Mu-type opioid receptor Cavia cutleri 1778 ChEMBL 10.1021/jm960319n 10.7270/Q2F190DS 9057856 Calderon, SN; Rice, KC; Rothman, RB; Porreca, F; Flippen-Anderson, JL; Kayakiri, H; Xu, H; Becketts, K; Smith, LE; Bilsky, EJ; Davis, P; Horvath, R National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056543&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44275475 103952781 CHEMBL153648 ZINC22454240 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50050494 CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23-,24-/m0/s1 MCMMCRYPQBNCPH-DVKRWUGUSA-N 50001683 13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid::7-Benzyl-10-{[3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL294616::DPDPE Mu-type opioid receptor Cavia cutleri 7300 ChEMBL 10.1021/jm960319n 10.7270/Q2F190DS 9057856 Calderon, SN; Rice, KC; Rothman, RB; Porreca, F; Flippen-Anderson, JL; Kayakiri, H; Xu, H; Becketts, K; Smith, LE; Bilsky, EJ; Davis, P; Horvath, R National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001683&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299404 103916113 CHEMBL294616 ZINC27520031 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50050497 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C37H52N8O10/c1-19(2)30(36(54)40-18-28(39)47)45-37(55)31(20(3)4)44-35(53)27(17-29(48)49)43-34(52)26(16-22-9-7-6-8-10-22)42-32(50)21(5)41-33(51)25(38)15-23-11-13-24(46)14-12-23/h6-14,19-21,25-27,30-31,46H,15-18,38H2,1-5H3,(H2,39,47)(H,40,54)(H,41,51)(H,42,50)(H,43,52)(H,44,53)(H,45,55)(H,48,49)/t21-,25+,26+,27+,30+,31+/m1/s1 CJAORFIPPWIGPG-QXYJMILXSA-N 50001468 (S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::3-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL317956::H-Tyr-D-Ala-Phe-Asp-Val-Val-Gly-NH2::deltorphin C Mu-type opioid receptor Cavia cutleri 15000 ChEMBL 10.1021/jm960319n 10.7270/Q2F190DS 9057856 Calderon, SN; Rice, KC; Rothman, RB; Porreca, F; Flippen-Anderson, JL; Kayakiri, H; Xu, H; Becketts, K; Smith, LE; Bilsky, EJ; Davis, P; Horvath, R National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001468&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10055958 103915933 CHEMBL317956 C18097 ZINC95610551 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50050502 CCN(CC)C(=O)c1ccc(cc1)[C@@H](N1C[C@@H](C)N(CC=C)C[C@@H]1C)c1cccc(OC)c1 InChI=1S/C28H39N3O2/c1-7-17-30-19-22(5)31(20-21(30)4)27(25-11-10-12-26(18-25)33-6)23-13-15-24(16-14-23)28(32)29(8-2)9-3/h7,10-16,18,21-22,27H,1,8-9,17,19-20H2,2-6H3/t21-,22+,27-/m1/s1 KQWVAUSXZDRQPZ-UMTXDNHDSA-N 50039029 (+)-4-((alpha R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-methoxyphenyl)methyl)-N,N-diethylbenzamide::(+)-4-[(alpha-R)-alpha-[2S,5R]-4-allyl[2,5-dimethyl-1-piperazinyl]-3-methoxybenzyl]-N,N-diethylbenzamide::3-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(4-diethylcarbamoyl-phenyl)-methyl]-benzoic acid::4-((R)-((2R,5S)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-methoxyphenyl)methyl)-N,N-diethylbenzamide::4-((R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-methoxyphenyl)methyl)-N,N-diethylbenzamide::4-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide (SNC 80)::4-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide(SNC-80)::4-[(R)-((2R,5S)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-((R)-4-(S)-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-[(2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl](3-methoxyphenyl)-methyl]-N,N-diethylbenzamide::CHEMBL13470::SNC-80 Mu-type opioid receptor Cavia cutleri 5457 ChEMBL 10.1021/jm960319n 10.7270/Q2F190DS 9057856 Calderon, SN; Rice, KC; Rothman, RB; Porreca, F; Flippen-Anderson, JL; Kayakiri, H; Xu, H; Becketts, K; Smith, LE; Bilsky, EJ; Davis, P; Horvath, R National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039029&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 123924 103946292 CHEMBL13470 1611 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50050505 CCN(CC)C(=O)c1ccc(cc1)C(N1C[C@@H](C)N(CC=C)C[C@@H]1C)c1ccccc1 InChI=1S/C27H37N3O/c1-6-18-29-19-22(5)30(20-21(29)4)26(23-12-10-9-11-13-23)24-14-16-25(17-15-24)27(31)28(7-2)8-3/h6,9-17,21-22,26H,1,7-8,18-20H2,2-5H3/t21-,22+,26?/m1/s1 WGIDFDFAOQVAHY-SGNGHUOJSA-N 50056543 4-[((1R,2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-phenyl-methyl]-N,N-diethyl-benzamide::4-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-phenyl-methyl]-N,N-diethyl-benzamide::4-[(S)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-phenyl-methyl]-N,N-diethyl-benzamide::CHEMBL153648 Mu-type opioid receptor Cavia cutleri 8583 ChEMBL 10.1021/jm960319n 10.7270/Q2F190DS 9057856 Calderon, SN; Rice, KC; Rothman, RB; Porreca, F; Flippen-Anderson, JL; Kayakiri, H; Xu, H; Becketts, K; Smith, LE; Bilsky, EJ; Davis, P; Horvath, R National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056543&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44275475 103952781 CHEMBL153648 ZINC22454240 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50050506 CCN(CC)C(=O)c1ccc(cc1)[C@@H](N1C[C@@H](C)N(CC=C)C[C@@H]1C)c1cccc(I)c1 InChI=1S/C27H36IN3O/c1-6-16-30-18-21(5)31(19-20(30)4)26(24-10-9-11-25(28)17-24)22-12-14-23(15-13-22)27(32)29(7-2)8-3/h6,9-15,17,20-21,26H,1,7-8,16,18-19H2,2-5H3/t20-,21+,26-/m1/s1 LYCSRKIBELQQIZ-YZIHRLCOSA-N 50056544 4-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-iodo-phenyl)-methyl]-N,N-diethyl-benzamide::CHEMBL347712 Mu-type opioid receptor Cavia cutleri >3000 ChEMBL 10.1021/jm960319n 10.7270/Q2F190DS 9057856 Calderon, SN; Rice, KC; Rothman, RB; Porreca, F; Flippen-Anderson, JL; Kayakiri, H; Xu, H; Becketts, K; Smith, LE; Bilsky, EJ; Davis, P; Horvath, R National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056544 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056544&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10674108 103952782 CHEMBL347712 ZINC27761934 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50050509 CCN(CC)C(=O)c1ccc(cc1)[C@@H](N1C[C@@H](C)N(CC=C)C[C@@H]1C)c1cccc(F)c1 InChI=1S/C27H36FN3O/c1-6-16-30-18-21(5)31(19-20(30)4)26(24-10-9-11-25(28)17-24)22-12-14-23(15-13-22)27(32)29(7-2)8-3/h6,9-15,17,20-21,26H,1,7-8,16,18-19H2,2-5H3/t20-,21+,26-/m1/s1 CUYUGMHVGXPLGA-YZIHRLCOSA-N 50056548 4-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-fluoro-phenyl)-methyl]-N,N-diethyl-benzamide::CHEMBL159618 Mu-type opioid receptor Cavia cutleri 2596 ChEMBL 10.1021/jm960319n 10.7270/Q2F190DS 9057856 Calderon, SN; Rice, KC; Rothman, RB; Porreca, F; Flippen-Anderson, JL; Kayakiri, H; Xu, H; Becketts, K; Smith, LE; Bilsky, EJ; Davis, P; Horvath, R National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056548 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056548&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10410840 103952786 CHEMBL159618 ZINC22938559 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50050600 CC(C)CN1CCC23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)CC(=Cc1ccc2ccccc2c1)C4=O)ccc5O InChI=1S/C31H31NO4/c1-18(2)17-32-12-11-30-26-22-9-10-24(33)28(26)36-29(30)27(34)23(16-31(30,35)25(32)15-22)14-19-7-8-20-5-3-4-6-21(20)13-19/h3-10,13-14,18,25,29,33,35H,11-12,15-17H2,1-2H3/t25-,29+,30?,31-/m1/s1 UUQBOLXVOARDCW-ZZKXWHAXSA-N 50056632 10,17-dihydroxy-4-isobutyl-15-[1-(2-naphthyl)-(Z)-methylidene]-(5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::CHEMBL165410 Mu-type opioid receptor Cavia cutleri 51 ChEMBL 10.1021/jm960573f 10.7270/Q29887P2 9057861 Palmer, RB; Upthagrove, AL; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056632 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056632&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377733 103952870 CHEMBL165410 ZINC36221390 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50050602 Oc1ccc2C[C@H]3N(CC4CC4)CCC45[C@@H](Oc1c24)C(=O)C(C[C@@]35O)=Cc1cccc2ccccc12 InChI=1S/C31H29NO4/c33-24-11-10-21-15-25-31(35)16-22(14-20-6-3-5-19-4-1-2-7-23(19)20)27(34)29-30(31,26(21)28(24)36-29)12-13-32(25)17-18-8-9-18/h1-7,10-11,14,18,25,29,33,35H,8-9,12-13,15-17H2/t25-,29+,30?,31-/m1/s1 LDINXOXSKGHJMD-ZZKXWHAXSA-N 50056626 4-cyclopropylmethyl-10,17-dihydroxy-15-[1-(1-naphthyl)-(Z)-methylidene]-(5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::CHEMBL162267::CHEMBL434867 Mu-type opioid receptor Cavia cutleri 11 ChEMBL 10.1021/jm960573f 10.7270/Q29887P2 9057861 Palmer, RB; Upthagrove, AL; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056626 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056626&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377757 103952864 CHEMBL162267CHEMBL434867 ZINC13761226 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50050605 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)\C(C[C@@]35O)=C\c1ccccc1 InChI=1S/C27H27NO4/c29-20-9-8-18-13-21-27(31)14-19(12-16-4-2-1-3-5-16)23(30)25-26(27,22(18)24(20)32-25)10-11-28(21)15-17-6-7-17/h1-5,8-9,12,17,21,25,29,31H,6-7,10-11,13-15H2/b19-12+/t21-,25+,26+,27-/m1/s1 WXOUFNFMPVMGFZ-BDQAUFNLSA-N 50454798 7-Benzylidenenaltrexone::BNTX Mu-type opioid receptor Cavia cutleri 26 ChEMBL 10.1021/jm960573f 10.7270/Q29887P2 9057861 Palmer, RB; Upthagrove, AL; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50454798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50454798&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5310988 225146325 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50050608 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)\C(C[C@@]35O)=C/c1ccccc1 InChI=1S/C27H27NO4/c29-20-9-8-18-13-21-27(31)14-19(12-16-4-2-1-3-5-16)23(30)25-26(27,22(18)24(20)32-25)10-11-28(21)15-17-6-7-17/h1-5,8-9,12,17,21,25,29,31H,6-7,10-11,13-15H2/b19-12-/t21-,25+,26+,27-/m1/s1 WXOUFNFMPVMGFZ-XEGDMQTMSA-N 50450986 CHEMBL101519 Mu-type opioid receptor Cavia cutleri 33 ChEMBL 10.1021/jm960573f 10.7270/Q29887P2 9057861 Palmer, RB; Upthagrove, AL; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50450986 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50450986&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 6438353 225145224 CHEMBL101519 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50050611 Oc1ccc2C[C@H]3N(CC4CC4)CCC45[C@@H](Oc1c24)C(=O)C(C[C@@]35O)=Cc1c2ccccc2cc2ccccc12 InChI=1S/C35H31NO4/c37-28-12-11-23-17-29-35(39)18-24(16-27-25-7-3-1-5-21(25)15-22-6-2-4-8-26(22)27)31(38)33-34(35,30(23)32(28)40-33)13-14-36(29)19-20-9-10-20/h1-8,11-12,15-16,20,29,33,37,39H,9-10,13-14,17-19H2/t29-,33+,34?,35-/m1/s1 VOALNYMYZLUFTA-QXBYUJLMSA-N 50056625 15-[1-(9-anthryl)-(Z)-methylidene]-4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::CHEMBL349940::CHEMBL350601 Mu-type opioid receptor Cavia cutleri 110 ChEMBL 10.1021/jm960573f 10.7270/Q29887P2 9057861 Palmer, RB; Upthagrove, AL; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056625 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056625&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377417 103952863 CHEMBL349940CHEMBL350601 ZINC27184091 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50050615 Oc1ccc2C[C@H]3N(CC4CC4)CCC45[C@@H](Oc1c24)C(=O)C(C[C@@]35O)=Cc1ccc(cc1)-c1ccccc1 InChI=1S/C33H31NO4/c35-26-13-12-24-17-27-33(37)18-25(16-20-8-10-23(11-9-20)22-4-2-1-3-5-22)29(36)31-32(33,28(24)30(26)38-31)14-15-34(27)19-21-6-7-21/h1-5,8-13,16,21,27,31,35,37H,6-7,14-15,17-19H2/t27-,31+,32?,33-/m1/s1 DVOIJAPNWLCYFS-VTZXKIFDSA-N 50056629 4-cyclopropylmethyl-10,17-dihydroxy-15-[1-(4-phenylphenyl)-(E)-methylidene]-(5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::CHEMBL162048::CHEMBL355188 Mu-type opioid receptor Cavia cutleri 210 ChEMBL 10.1021/jm960573f 10.7270/Q29887P2 9057861 Palmer, RB; Upthagrove, AL; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056629 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056629&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377655 103952867 CHEMBL355188CHEMBL162048 ZINC13761224 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50050618 Oc1ccc2C[C@H]3N(CC4CC4)CCC45[C@@H](Oc1c24)C(=O)C(C[C@@]35O)=Cc1cccc2ccccc12 InChI=1S/C31H29NO4/c33-24-11-10-21-15-25-31(35)16-22(14-20-6-3-5-19-4-1-2-7-23(19)20)27(34)29-30(31,26(21)28(24)36-29)12-13-32(25)17-18-8-9-18/h1-7,10-11,14,18,25,29,33,35H,8-9,12-13,15-17H2/t25-,29+,30?,31-/m1/s1 LDINXOXSKGHJMD-ZZKXWHAXSA-N 50056626 4-cyclopropylmethyl-10,17-dihydroxy-15-[1-(1-naphthyl)-(Z)-methylidene]-(5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::CHEMBL162267::CHEMBL434867 Mu-type opioid receptor Cavia cutleri 36 ChEMBL 10.1021/jm960573f 10.7270/Q29887P2 9057861 Palmer, RB; Upthagrove, AL; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056626 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056626&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377757 103952864 CHEMBL162267CHEMBL434867 ZINC13761226 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50050619 Oc1ccc2C[C@H]3N(CC4CC4)CCC45[C@@H](Oc1c24)C(=O)C(C[C@@]35O)=Cc1ccc(cc1)-c1ccccc1 InChI=1S/C33H31NO4/c35-26-13-12-24-17-27-33(37)18-25(16-20-8-10-23(11-9-20)22-4-2-1-3-5-22)29(36)31-32(33,28(24)30(26)38-31)14-15-34(27)19-21-6-7-21/h1-5,8-13,16,21,27,31,35,37H,6-7,14-15,17-19H2/t27-,31+,32?,33-/m1/s1 DVOIJAPNWLCYFS-VTZXKIFDSA-N 50056629 4-cyclopropylmethyl-10,17-dihydroxy-15-[1-(4-phenylphenyl)-(E)-methylidene]-(5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::CHEMBL162048::CHEMBL355188 Mu-type opioid receptor Cavia cutleri 50 ChEMBL 10.1021/jm960573f 10.7270/Q29887P2 9057861 Palmer, RB; Upthagrove, AL; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056629 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056629&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377655 103952867 CHEMBL355188CHEMBL162048 ZINC13761224 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50050620 Oc1ccc2C[C@H]3N(CC4CC4)CCC45[C@@H](Oc1c24)C(=O)C(C[C@@]35O)=Cc1c2ccccc2cc2ccccc12 InChI=1S/C35H31NO4/c37-28-12-11-23-17-29-35(39)18-24(16-27-25-7-3-1-5-21(25)15-22-6-2-4-8-26(22)27)31(38)33-34(35,30(23)32(28)40-33)13-14-36(29)19-20-9-10-20/h1-8,11-12,15-16,20,29,33,37,39H,9-10,13-14,17-19H2/t29-,33+,34?,35-/m1/s1 VOALNYMYZLUFTA-QXBYUJLMSA-N 50056625 15-[1-(9-anthryl)-(Z)-methylidene]-4-cyclopropylmethyl-10,17-dihydroxy-(5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::CHEMBL349940::CHEMBL350601 Mu-type opioid receptor Cavia cutleri 34 ChEMBL 10.1021/jm960573f 10.7270/Q29887P2 9057861 Palmer, RB; Upthagrove, AL; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056625 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056625&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377417 103952863 CHEMBL349940CHEMBL350601 ZINC27184091 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50050627 Oc1ccc2C[C@H]3N(CC4CC4)CCC45[C@@H](Oc1c24)C(=O)C(C[C@@]35O)=Cc1ccc2ccccc2c1 InChI=1S/C31H29NO4/c33-24-10-9-22-15-25-31(35)16-23(14-19-7-8-20-3-1-2-4-21(20)13-19)27(34)29-30(31,26(22)28(24)36-29)11-12-32(25)17-18-5-6-18/h1-4,7-10,13-14,18,25,29,33,35H,5-6,11-12,15-17H2/t25-,29+,30?,31-/m1/s1 COXHSSWZQBEBOP-ZZKXWHAXSA-N 50056627 4-cyclopropylmethyl-10,17-dihydroxy-15-[1-(2-naphthyl)-(E)-methylidene]-(5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::CHEMBL164577 Mu-type opioid receptor Cavia cutleri 23 ChEMBL 10.1021/jm960573f 10.7270/Q29887P2 9057861 Palmer, RB; Upthagrove, AL; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056627 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056627&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377678 103952865 CHEMBL164577 ZINC13652313 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50050628 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1 DQCKKXVULJGBQN-XFWGSAIBSA-N 60212 (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::MLS000069607::NALTREXONE HYDROCHLORIDE::SMR000058767::US10988481, Compound NTX::US9107954, naltrexone::cid_5485201 Mu-type opioid receptor Cavia cutleri 0.80 ChEMBL 10.1021/jm960573f 10.7270/Q29887P2 9057861 Palmer, RB; Upthagrove, AL; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60212&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5360515 252639834 DB00704 C07253 ZINC00001773 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057584 CC(C)[C@@H]1NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](CCCCNC(=O)CC[C@@H](NC(=O)[C@H](NC1=O)C(C)C)C(N)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C43H61N9O11/c1-23(2)35-42(62)47-29(37(45)57)17-18-33(54)46-19-9-8-12-30(48-38(58)28(44)20-26-13-15-27(53)16-14-26)39(59)49-31(21-25-10-6-5-7-11-25)40(60)50-32(22-34(55)56)41(61)51-36(24(3)4)43(63)52-35/h5-7,10-11,13-16,23-24,28-32,35-36,53H,8-9,12,17-22,44H2,1-4H3,(H2,45,57)(H,46,54)(H,47,62)(H,48,58)(H,49,59)(H,50,60)(H,51,61)(H,52,63)(H,55,56)/t28-,29+,30+,31-,32+,35+,36-/m0/s1 UACUTZCMVVGDIS-YXOOPPKZSA-N 50001461 CHEMBL338466::{23-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-2-benzyl-14-carbamoyl-8,11-diisopropyl-3,6,9,12,17,24-hexaoxo-1,4,7,10,13,18hexaaza-cyclotetracos-5-yl}-acetic acid Mu-type opioid receptor Cavia cutleri 380 ChEMBL 10.1021/jm00099a025 10.7270/Q2H70DRH 1331451 Schiller, PW; Weltrowska, G; Nguyen, TM; Wilkes, BC; Chung, NN; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001461 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001461&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44351646 103915926 CHEMBL338466 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057586 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C44H56N8O10/c1-24(2)37(42(60)47-22-35(46)54)51-43(61)38(25(3)4)50-40(58)33(21-36(55)56)48-39(57)32(19-26-10-6-5-7-11-26)49-41(59)34-20-28-12-8-9-13-29(28)23-52(34)44(62)31(45)18-27-14-16-30(53)17-15-27/h5-17,24-25,31-34,37-38,53H,18-23,45H2,1-4H3,(H2,46,54)(H,47,60)(H,48,57)(H,49,59)(H,50,58)(H,51,61)(H,55,56)/t31-,32-,33-,34-,37-,38-/m0/s1 YYWLKPQNTXSHKT-FFIZALLVSA-N 50001458 3-[2-({2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-3-phenyl-propionylamino]-N-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL339089 Mu-type opioid receptor Cavia cutleri >65000 ChEMBL 10.1021/jm00099a025 10.7270/Q2H70DRH 1331451 Schiller, PW; Weltrowska, G; Nguyen, TM; Wilkes, BC; Chung, NN; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001458&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9988147 103915923 CHEMBL339089 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057587 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C28H37N5O7/c1-17(2)12-23(28(39)40)33-27(38)22(14-18-6-4-3-5-7-18)32-25(36)16-30-24(35)15-31-26(37)21(29)13-19-8-10-20(34)11-9-19/h3-11,17,21-23,34H,12-16,29H2,1-2H3,(H,30,35)(H,31,37)(H,32,36)(H,33,38)(H,39,40)/t21-,22-,23-/m0/s1 URLZCHNOLZSCCA-VABKMULXSA-N 50001465 (S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::([Leu]-enkephalin)2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::(enkephalin)2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-1-oxo-3-phenyl-propylamino]-4-methyl-pentanoic acid::2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::2-[1-[1-amino-2-(4-hydroxyphenyl)-(1S)-ethylcarboxamidomethylcarboxamidomethylcarboxamido]-2-phenyl-(1S)-ethylcarboxamido]-4-methyl-(2S)-pentanoic acid::2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid(Enkephalin)::2-{1-[1-amino-2-(4-hydroxyphenyl)ethylcarboxamidomethylcarboxamidomethylcarboxamido]-2-phenylethylcarboxamido}-4-methylpentanoic acid::CHEMBL8234::ENKEPHALIN::Leu-ENKEPHALIN::Leu5-Enkephalin::Tyr-Gly-Gly-Phe-Leu-OH Mu-type opioid receptor Cavia cutleri 246 ChEMBL 10.1021/jm00099a025 10.7270/Q2H70DRH 1331451 Schiller, PW; Weltrowska, G; Nguyen, TM; Wilkes, BC; Chung, NN; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001465&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 461776 103915930 CHEMBL8234 ZINC14952116 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057588 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C37H52N8O10/c1-19(2)30(36(54)40-18-28(39)47)45-37(55)31(20(3)4)44-35(53)27(17-29(48)49)43-34(52)26(16-22-9-7-6-8-10-22)42-32(50)21(5)41-33(51)25(38)15-23-11-13-24(46)14-12-23/h6-14,19-21,25-27,30-31,46H,15-18,38H2,1-5H3,(H2,39,47)(H,40,54)(H,41,51)(H,42,50)(H,43,52)(H,44,53)(H,45,55)(H,48,49)/t21-,25+,26-,27+,30+,31+/m1/s1 CJAORFIPPWIGPG-ZJKHCNMWSA-N 50001464 3-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL337898::Deltorphin I Mu-type opioid receptor Cavia cutleri 11900 ChEMBL 10.1021/jm00099a025 10.7270/Q2H70DRH 1331451 Schiller, PW; Weltrowska, G; Nguyen, TM; Wilkes, BC; Chung, NN; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001464 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001464&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10101700 103915929 CHEMBL337898 ZINC95611313 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057597 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C37H52N8O10/c1-19(2)30(36(54)40-18-28(39)47)45-37(55)31(20(3)4)44-35(53)27(17-29(48)49)43-34(52)26(16-22-9-7-6-8-10-22)42-32(50)21(5)41-33(51)25(38)15-23-11-13-24(46)14-12-23/h6-14,19-21,25-27,30-31,46H,15-18,38H2,1-5H3,(H2,39,47)(H,40,54)(H,41,51)(H,42,50)(H,43,52)(H,44,53)(H,45,55)(H,48,49)/t21-,25+,26+,27+,30+,31+/m1/s1 CJAORFIPPWIGPG-QXYJMILXSA-N 50001468 (S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::3-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL317956::H-Tyr-D-Ala-Phe-Asp-Val-Val-Gly-NH2::deltorphin C Mu-type opioid receptor Cavia cutleri 854 ChEMBL 10.1021/jm00099a025 10.7270/Q2H70DRH 1331451 Schiller, PW; Weltrowska, G; Nguyen, TM; Wilkes, BC; Chung, NN; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001468&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10055958 103915933 CHEMBL317956 C18097 ZINC95610551 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057603 CC(C)[C@H]1NC(=O)[C@@H](NC(=O)[C@H](CC(=O)NCCC[C@@H](NC1=O)C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C InChI=1S/C40H57N9O9/c1-21(2)32-39(57)45-28(34(42)52)12-9-17-43-31(51)20-30(38(56)48-33(22(3)4)40(58)49-32)47-37(55)29(19-24-10-7-6-8-11-24)46-35(53)23(5)44-36(54)27(41)18-25-13-15-26(50)16-14-25/h6-8,10-11,13-16,21-23,27-30,32-33,50H,9,12,17-20,41H2,1-5H3,(H2,42,52)(H,43,51)(H,44,54)(H,45,57)(H,46,53)(H,47,55)(H,48,56)(H,49,58)/t23-,27+,28-,29+,30+,32-,33+/m1/s1 CPCISRCHDNVGRE-SHHOUWCKSA-N 50001469 15-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-2,5-diisopropyl-3,6,13,16-tetraoxo-1,4,7,12tetraaza-cyclohexadecane-8-carboxylic acid amide::CHEMBL129815 Mu-type opioid receptor Cavia cutleri 251 ChEMBL 10.1021/jm00099a025 10.7270/Q2H70DRH 1331451 Schiller, PW; Weltrowska, G; Nguyen, TM; Wilkes, BC; Chung, NN; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001469 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001469&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44351739 103915934 CHEMBL129815 ZINC95549231 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057615 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C38H52N8O10/c1-19(2)31(36(54)41-17-29(40)48)45-37(55)32(20(3)4)44-34(52)27(16-30(49)50)43-35(53)28-15-23-8-6-7-9-24(23)18-46(28)38(56)21(5)42-33(51)26(39)14-22-10-12-25(47)13-11-22/h6-13,19-21,26-28,31-32,47H,14-18,39H2,1-5H3,(H2,40,48)(H,41,54)(H,42,51)(H,43,53)(H,44,52)(H,45,55)(H,49,50)/t21-,26+,27+,28+,31+,32+/m1/s1 JOXXADDFFWZHEE-JMZWVCJUSA-N 50001460 3-[(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionyl}-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl)-amino]-N-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL330991::H-Tyr-D-Ala-Tic-Asp-Val-Val-Gly-NH2 Mu-type opioid receptor Cavia cutleri 14500 ChEMBL 10.1021/jm00099a025 10.7270/Q2H70DRH 1331451 Schiller, PW; Weltrowska, G; Nguyen, TM; Wilkes, BC; Chung, NN; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001460&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10485385 103915925 CHEMBL330991 ZINC95611127 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057616 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)C1(Cc2ccccc2C1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C38H52N8O10/c1-19(2)30(35(54)41-18-28(40)48)45-36(55)31(20(3)4)44-34(53)27(15-29(49)50)43-37(56)38(16-23-8-6-7-9-24(23)17-38)46-32(51)21(5)42-33(52)26(39)14-22-10-12-25(47)13-11-22/h6-13,19-21,26-27,30-31,47H,14-18,39H2,1-5H3,(H2,40,48)(H,41,54)(H,42,52)(H,43,56)(H,44,53)(H,45,55)(H,46,51)(H,49,50)/t21-,26+,27+,30+,31+/m1/s1 QZYUFPDOTMWDCQ-UZHHEQFGSA-N 50001462 3-[(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-indane-2-carbonyl)-amino]-N-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL124435::H-Tyr-D-Ala-Aic-Asp-Val-Val-Gly-NH2 Mu-type opioid receptor Cavia cutleri 290 ChEMBL 10.1021/jm00099a025 10.7270/Q2H70DRH 1331451 Schiller, PW; Weltrowska, G; Nguyen, TM; Wilkes, BC; Chung, NN; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001462&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10010455 103915927 CHEMBL124435 ZINC95548262 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057618 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CCCNC(=O)C[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(N)=O InChI=1S/C27H34N6O6/c28-19(13-17-8-10-18(34)11-9-17)25(37)31-20-7-4-12-30-23(35)15-21(24(29)36)32-27(39)22(33-26(20)38)14-16-5-2-1-3-6-16/h1-3,5-6,8-11,19-22,34H,4,7,12-15,28H2,(H2,29,36)(H,30,35)(H,31,37)(H,32,39)(H,33,38)/t19-,20+,21-,22-/m0/s1 HNDAPGXWFDLKOJ-LRSLUSHPSA-N 50001467 12-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-2-benzyl-3,7,13-trioxo-1,4,8triaza-cyclotridecane-5-carboxylic acid amide::CHEMBL63407 Mu-type opioid receptor Cavia cutleri 36 ChEMBL 10.1021/jm00099a025 10.7270/Q2H70DRH 1331451 Schiller, PW; Weltrowska, G; Nguyen, TM; Wilkes, BC; Chung, NN; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001467&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 125942 103915932 CHEMBL63407 ZINC26181761 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057620 CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CC(O)=O)C(N)=O InChI=1S/C53H66N8O10/c1-4-5-20-40(48(66)57-41(47(55)65)30-46(63)64)56-49(67)42(25-32(2)3)58-50(68)43(27-33-14-8-6-9-15-33)59-51(69)44(28-34-16-10-7-11-17-34)60-52(70)45-29-36-18-12-13-19-37(36)31-61(45)53(71)39(54)26-35-21-23-38(62)24-22-35/h6-19,21-24,32,39-45,62H,4-5,20,25-31,54H2,1-3H3,(H2,55,65)(H,56,67)(H,57,66)(H,58,68)(H,59,69)(H,60,70)(H,63,64)/t39-,40-,41-,42-,43-,44-,45-/m0/s1 MUZOAQPSQBMUFS-FXRUNAACSA-N 50001466 3-[2-(2-{2-[2-({2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-3-phenyl-propionylamino]-3-phenyl-propionylamino}-4-methyl-pentanoylamino)-hexanoylamino]-succinamic acid::CHEMBL262312 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm00099a025 10.7270/Q2H70DRH 1331451 Schiller, PW; Weltrowska, G; Nguyen, TM; Wilkes, BC; Chung, NN; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001466 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001466&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10350963 103915931 CHEMBL262312 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057602 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCC(=O)NCCCC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N1)C(C)C)C(=O)NCC(N)=O InChI=1S/C41H59N9O9/c1-23(2)34(40(58)45-22-32(43)52)50-41(59)35(24(3)4)49-38(56)30-17-18-33(53)44-19-9-8-12-29(46-36(54)28(42)20-26-13-15-27(51)16-14-26)37(55)48-31(39(57)47-30)21-25-10-6-5-7-11-25/h5-7,10-11,13-16,23-24,28-31,34-35,51H,8-9,12,17-22,42H2,1-4H3,(H2,43,52)(H,44,53)(H,45,58)(H,46,54)(H,47,57)(H,48,55)(H,49,56)(H,50,59)/t28-,29+,30-,31-,34-,35-/m0/s1 ATPLUIZXQQGNRT-BLZAPJNSSA-N 50001463 14-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-2-benzyl-3,8,15-trioxo-1,4,9triaza-cyclopentadecane-5-carboxylic acid {1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-amide::CHEMBL132164 Mu-type opioid receptor Cavia cutleri 102 ChEMBL 10.1021/jm00099a025 10.7270/Q2H70DRH 1331451 Schiller, PW; Weltrowska, G; Nguyen, TM; Wilkes, BC; Chung, NN; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001463 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001463&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10395647 103915928 CHEMBL132164 ZINC95549234 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057850 CC1(C)SSC[C@@H](NC(=O)[C@H]2NCC[C@@H]2c2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(O)=O InChI=1S/C28H34N4O6S2/c1-28(2)23(27(37)38)32-24(34)20(14-16-6-4-3-5-7-16)30-25(35)21(15-39-40-28)31-26(36)22-19(12-13-29-22)17-8-10-18(33)11-9-17/h3-11,19-23,29,33H,12-15H2,1-2H3,(H,30,35)(H,31,36)(H,32,34)(H,37,38)/t19-,20+,21-,22+,23-/m1/s1 ZATPZTVNZBDUOD-ISBRNDMJSA-N 50455773 CHEMBL2370868 Mu-type opioid receptor Cavia cutleri 105 ChEMBL 10.1021/jm00101a030 10.7270/Q2N0174K 1333014 Mosberg, HI; Kroona, HB University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50455773 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50455773&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73353090 225146689 CHEMBL2370868 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50054591 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1 DQCKKXVULJGBQN-XFWGSAIBSA-N 60212 (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::MLS000069607::NALTREXONE HYDROCHLORIDE::SMR000058767::US10988481, Compound NTX::US9107954, naltrexone::cid_5485201 Mu-type opioid receptor Cavia cutleri 0.93 ChEMBL 10.1021/jm980290i 10.7270/Q2RB73Q6 9767649 Thomas, JB; Zheng, X; Mascarella, SW; Rothman, RB; Dersch, CM; Partilla, JS; Flippen-Anderson, JL; George, CF; Cantrell, BE; Zimmerman, DM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60212&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5360515 252639834 DB00704 C07253 ZINC00001773 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50054600 C[C@H]1C2CCCC1(CCN2C)c1cccc(O)c1 InChI=1S/C16H23NO/c1-12-15-7-4-8-16(12,9-10-17(15)2)13-5-3-6-14(18)11-13/h3,5-6,11-12,15,18H,4,7-10H2,1-2H3/t12-,15?,16?/m0/s1 JBSRPCWYMOJXAM-JQRITLKVSA-N 50067446 3-((R)-2,9-Dimethyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenol::CHEMBL133815 Mu-type opioid receptor Cavia cutleri 21 ChEMBL 10.1021/jm980290i 10.7270/Q2RB73Q6 9767649 Thomas, JB; Zheng, X; Mascarella, SW; Rothman, RB; Dersch, CM; Partilla, JS; Flippen-Anderson, JL; George, CF; Cantrell, BE; Zimmerman, DM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50067446 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50067446&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44354228 103961886 CHEMBL133815 ZINC13454266 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50054602 C[C@H]1C2CCCC1(CCN2CCc1ccccc1)c1cccc(O)c1 InChI=1S/C23H29NO/c1-18-22-11-6-13-23(18,20-9-5-10-21(25)17-20)14-16-24(22)15-12-19-7-3-2-4-8-19/h2-5,7-10,17-18,22,25H,6,11-16H2,1H3/t18-,22?,23?/m0/s1 FJRARMQVERMSNJ-NWLLBJEDSA-N 50067447 3-((R)-9-Methyl-2-phenethyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenol::CHEMBL334898 Mu-type opioid receptor Cavia cutleri 0.34 ChEMBL 10.1021/jm980290i 10.7270/Q2RB73Q6 9767649 Thomas, JB; Zheng, X; Mascarella, SW; Rothman, RB; Dersch, CM; Partilla, JS; Flippen-Anderson, JL; George, CF; Cantrell, BE; Zimmerman, DM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50067447 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50067447&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 22977851 103961887 CHEMBL334898 ZINC27332293 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50054837 CC(C)(C)c1ccc(cc1)C(N1CCN(Cc2ccccc2)CC1)c1cccc(O)c1 InChI=1S/C28H34N2O/c1-28(2,3)25-14-12-23(13-15-25)27(24-10-7-11-26(31)20-24)30-18-16-29(17-19-30)21-22-8-5-4-6-9-22/h4-15,20,27,31H,16-19,21H2,1-3H3 PNVIEMCZBRMSPB-UHFFFAOYSA-N 50068132 3-[(4-Benzyl-piperazin-1-yl)-(4-tert-butyl-phenyl)-methyl]-phenol::CHEMBL143592::SL-3111 Mu-type opioid receptor Cavia cutleri 39000 ChEMBL 10.1021/jm980374r 10.7270/Q2DZ07FQ 9822547 Liao, S; Alfaro-Lopez, J; Shenderovich, MD; Hosohata, K; Lin, J; Li, X; Stropova, D; Davis, P; Jernigan, KA; Porreca, F; Yamamura, HI; Hruby, VJ The University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068132&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9909743 103962468 CHEMBL143592 ZINC22939106 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50054843 CC(C)(C)c1ccc(cc1)C(N1CCN(Cc2ccccc2)CC1)c1cccc(O)c1 InChI=1S/C28H34N2O/c1-28(2,3)25-14-12-23(13-15-25)27(24-10-7-11-26(31)20-24)30-18-16-29(17-19-30)21-22-8-5-4-6-9-22/h4-15,20,27,31H,16-19,21H2,1-3H3 PNVIEMCZBRMSPB-UHFFFAOYSA-N 50068132 3-[(4-Benzyl-piperazin-1-yl)-(4-tert-butyl-phenyl)-methyl]-phenol::CHEMBL143592::SL-3111 Mu-type opioid receptor Cavia cutleri 7600 ChEMBL 10.1021/jm980374r 10.7270/Q2DZ07FQ 9822547 Liao, S; Alfaro-Lopez, J; Shenderovich, MD; Hosohata, K; Lin, J; Li, X; Stropova, D; Davis, P; Jernigan, KA; Porreca, F; Yamamura, HI; Hruby, VJ The University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068132&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9909743 103962468 CHEMBL143592 ZINC22939106 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50054849 Oc1cccc(c1)C(N1CCN(Cc2ccccc2)CC1)c1ccccc1 InChI=1S/C24H26N2O/c27-23-13-7-12-22(18-23)24(21-10-5-2-6-11-21)26-16-14-25(15-17-26)19-20-8-3-1-4-9-20/h1-13,18,24,27H,14-17,19H2 HZZCYHBEEHSRRI-UHFFFAOYSA-N 50068136 3-[(4-Benzyl-piperazin-1-yl)-phenyl-methyl]-phenol::CHEMBL356587 Mu-type opioid receptor Cavia cutleri 1250 ChEMBL 10.1021/jm980374r 10.7270/Q2DZ07FQ 9822547 Liao, S; Alfaro-Lopez, J; Shenderovich, MD; Hosohata, K; Lin, J; Li, X; Stropova, D; Davis, P; Jernigan, KA; Porreca, F; Yamamura, HI; Hruby, VJ The University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068136&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10765126 103962472 CHEMBL356587 ZINC22939097 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057154 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 3.3 ChEMBL 10.1021/jm00094a006 10.7270/Q2P26ZR7 1323679 Vecchietti, V; Clarke, GD; Colle, R; Dondio, G; Giardina, G; Petrone, G; Sbacchi, M Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057160 Clc1ccc(CC(=O)N2CCc3ccccc3C2CN2CCCC2)cc1Cl InChI=1S/C22H24Cl2N2O/c23-19-8-7-16(13-20(19)24)14-22(27)26-12-9-17-5-1-2-6-18(17)21(26)15-25-10-3-4-11-25/h1-2,5-8,13,21H,3-4,9-12,14-15H2 ATTHVGBIVYJECI-UHFFFAOYSA-N 50001108 2-(3,4-Dichloro-phenyl)-1-(1-pyrrolidin-1-ylmethyl-3,4-dihydro-1H-isoquinolin-2-yl)-ethanone::2-(3,4-Dichloro-phenyl)-1-(1-pyrrolidin-1-ylmethyl-3,4-dihydro-1H-isoquinolin-2-yl)-ethanone;C4H6O6::2-(3,4-Dichloro-phenyl)-1-(1-pyrrolidin-1-ylmethyl-3,4-dihydro-1H-isoquinolin-2-yl)-ethanone;HCl::CHEMBL275025 Mu-type opioid receptor Cavia cutleri 30 ChEMBL 10.1021/jm00094a006 10.7270/Q2P26ZR7 1323679 Vecchietti, V; Clarke, GD; Colle, R; Dondio, G; Giardina, G; Petrone, G; Sbacchi, M Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001108 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001108&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14726012 103915600 CHEMBL275025 ZINC13726265 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057162 C[C@@H]1CN(C(CN2CCCC2)c2ccccc12)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C23H26Cl2N2O/c1-16-14-27(23(28)13-17-8-9-20(24)21(25)12-17)22(15-26-10-4-5-11-26)19-7-3-2-6-18(16)19/h2-3,6-9,12,16,22H,4-5,10-11,13-15H2,1H3/t16-,22?/m1/s1 HHXMAUKRPCOLOF-XESZBRCGSA-N 50001105 2-(3,4-Dichloro-phenyl)-1-(4-methyl-1-pyrrolidin-1-ylmethyl-3,4-dihydro-1H-isoquinolin-2-yl)-ethanone::CHEMBL101396 Mu-type opioid receptor Cavia cutleri 57 ChEMBL 10.1021/jm00094a006 10.7270/Q2P26ZR7 1323679 Vecchietti, V; Clarke, GD; Colle, R; Dondio, G; Giardina, G; Petrone, G; Sbacchi, M Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001105 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001105&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44331844 103915597 CHEMBL101396 ZINC26744653 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057164 CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C19H26Cl2N2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17-,18-/m1/s1 VQLPLYSROCPWFF-QZTJIDSGSA-N 50000296 CHEMBL441765::CHEMBL482811::U-50488H::US11492374, ID 1 Mu-type opioid receptor Cavia cutleri 616 ChEMBL 10.1021/jm00094a006 10.7270/Q2P26ZR7 1323679 Vecchietti, V; Clarke, GD; Colle, R; Dondio, G; Giardina, G; Petrone, G; Sbacchi, M Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000296&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036289 103914903 73358 CHEMBL482811CHEMBL441765 1654 C11796 ZINC00643032 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057165 CC1(C)CN(C(CN2CCCC2)c2ccccc12)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C24H28Cl2N2O/c1-24(2)16-28(23(29)14-17-9-10-20(25)21(26)13-17)22(15-27-11-5-6-12-27)18-7-3-4-8-19(18)24/h3-4,7-10,13,22H,5-6,11-12,14-16H2,1-2H3 GTNQJYKMLZNFMJ-UHFFFAOYSA-N 50001106 2-(3,4-Dichloro-phenyl)-1-(4,4-dimethyl-1-pyrrolidin-1-ylmethyl-3,4-dihydro-1H-isoquinolin-2-yl)-ethanone; hydrochloride::CHEMBL554885 Mu-type opioid receptor Cavia cutleri 239 ChEMBL 10.1021/jm00094a006 10.7270/Q2P26ZR7 1323679 Vecchietti, V; Clarke, GD; Colle, R; Dondio, G; Giardina, G; Petrone, G; Sbacchi, M Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001106 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001106&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9824054 103915598 CHEMBL554885 ZINC13726261 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057166 Oc1cccc2C(CN3CCCC3)N(CCc12)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C22H24Cl2N2O2/c23-18-7-6-15(12-19(18)24)13-22(28)26-11-8-17-16(4-3-5-21(17)27)20(26)14-25-9-1-2-10-25/h3-7,12,20,27H,1-2,8-11,13-14H2 WRQRXSLULFCZOJ-UHFFFAOYSA-N 50001107 2-(3,4-Dichloro-phenyl)-1-(5-hydroxy-1-pyrrolidin-1-ylmethyl-3,4-dihydro-1H-isoquinolin-2-yl)-ethanone; hydrochloride::CHEMBL554426::CHEMBL66018 Mu-type opioid receptor Cavia cutleri 0.490000 ChEMBL 10.1021/jm00094a006 10.7270/Q2P26ZR7 1323679 Vecchietti, V; Clarke, GD; Colle, R; Dondio, G; Giardina, G; Petrone, G; Sbacchi, M Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001107&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9828569 103915599 CHEMBL554426CHEMBL66018 ZINC13726249 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057167 C[C@@H]1Cc2ccccc2C(CN2CCCC2)N1C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C23H26Cl2N2O/c1-16-12-18-6-2-3-7-19(18)22(15-26-10-4-5-11-26)27(16)23(28)14-17-8-9-20(24)21(25)13-17/h2-3,6-9,13,16,22H,4-5,10-12,14-15H2,1H3/t16-,22?/m1/s1 JJHUGZVLLUVXKL-XESZBRCGSA-N 50001104 2-(3,4-Dichloro-phenyl)-1-(3-methyl-1-pyrrolidin-1-ylmethyl-3,4-dihydro-1H-isoquinolin-2-yl)-ethanone::CHEMBL102160 Mu-type opioid receptor Cavia cutleri 11 ChEMBL 10.1021/jm00094a006 10.7270/Q2P26ZR7 1323679 Vecchietti, V; Clarke, GD; Colle, R; Dondio, G; Giardina, G; Petrone, G; Sbacchi, M Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001104 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001104&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44331845 103915596 CHEMBL102160 ZINC26744130 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50055076 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1 DQCKKXVULJGBQN-XFWGSAIBSA-N 60212 (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::MLS000069607::NALTREXONE HYDROCHLORIDE::SMR000058767::US10988481, Compound NTX::US9107954, naltrexone::cid_5485201 Mu-type opioid receptor Cavia cutleri 0.930000 ChEMBL 10.1021/jm980511k 10.7270/Q2P26ZT4 9857089 Thomas, JB; Fall, MJ; Cooper, JB; Rothman, RB; Mascarella, SW; Xu, H; Partilla, JS; Dersch, CM; McCullough, KB; Cantrell, BE; Zimmerman, DM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60212&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5360515 252639834 DB00704 C07253 ZINC00001773 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50055077 CC(C)[C@@H](CN1CC[C@](C)([C@@H](C)C1)c1cccc(O)c1)NC(=O)CCc1ccc(O)cc1 InChI=1S/C27H38N2O3/c1-19(2)25(28-26(32)13-10-21-8-11-23(30)12-9-21)18-29-15-14-27(4,20(3)17-29)22-6-5-7-24(31)16-22/h5-9,11-12,16,19-20,25,30-31H,10,13-15,17-18H2,1-4H3,(H,28,32)/t20-,25+,27+/m0/s1 BOXRUELCJUEBJH-FBQMUFCQSA-N 50102710 3-(4-Hydroxy-phenyl)-N-{(S)-1-[(3R,4R)-4-(3-hydroxy-phenyl)-3,4-dimethyl-piperidin-1-ylmethyl]-2-methyl-propyl}-propionamide::3-(4-Hydroxy-phenyl)-N-{1-[4-(3-hydroxy-phenyl)-3,4-dimethyl-piperidin-1-ylmethyl]-2-methyl-propyl}-propionamide::CHEMBL10986 Mu-type opioid receptor Cavia cutleri 7.3 ChEMBL 10.1021/jm980511k 10.7270/Q2P26ZT4 9857089 Thomas, JB; Fall, MJ; Cooper, JB; Rothman, RB; Mascarella, SW; Xu, H; Partilla, JS; Dersch, CM; McCullough, KB; Cantrell, BE; Zimmerman, DM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102710 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102710&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9804952 103999146 CHEMBL10986 ZINC04424128 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50055078 CC(C)C[C@@H](CN1CCC(C)(C(C)C1)c1cccc(O)c1)NC(=O)CCc1ccc(O)cc1 InChI=1S/C28H40N2O3/c1-20(2)16-24(29-27(33)13-10-22-8-11-25(31)12-9-22)19-30-15-14-28(4,21(3)18-30)23-6-5-7-26(32)17-23/h5-9,11-12,17,20-21,24,31-32H,10,13-16,18-19H2,1-4H3,(H,29,33)/t21?,24-,28?/m0/s1 RBEYXXYVZSWZGN-CJQCTXEWSA-N 50291971 3-(4-Hydroxy-phenyl)-N-{(S)-1-[4-(3-hydroxy-phenyl)-3,4-dimethyl-piperidin-1-ylmethyl]-3-methyl-butyl}-propionamide::CHEMBL149611 Mu-type opioid receptor Cavia cutleri 398 ChEMBL 10.1021/jm980511k 10.7270/Q2P26ZT4 9857089 Thomas, JB; Fall, MJ; Cooper, JB; Rothman, RB; Mascarella, SW; Xu, H; Partilla, JS; Dersch, CM; McCullough, KB; Cantrell, BE; Zimmerman, DM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291971&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44365664 104133523 CHEMBL149611 ZINC38151877 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50055079 CC(C)[C@@H](CN1CC[C@](C)([C@@H](C)C1)c1cccc(O)c1)NC(=O)CCc1ccc(O)cc1 InChI=1S/C27H38N2O3/c1-19(2)25(28-26(32)13-10-21-8-11-23(30)12-9-21)18-29-15-14-27(4,20(3)17-29)22-6-5-7-24(31)16-22/h5-9,11-12,16,19-20,25,30-31H,10,13-15,17-18H2,1-4H3,(H,28,32)/t20-,25+,27+/m0/s1 BOXRUELCJUEBJH-FBQMUFCQSA-N 50102710 3-(4-Hydroxy-phenyl)-N-{(S)-1-[(3R,4R)-4-(3-hydroxy-phenyl)-3,4-dimethyl-piperidin-1-ylmethyl]-2-methyl-propyl}-propionamide::3-(4-Hydroxy-phenyl)-N-{1-[4-(3-hydroxy-phenyl)-3,4-dimethyl-piperidin-1-ylmethyl]-2-methyl-propyl}-propionamide::CHEMBL10986 Mu-type opioid receptor Cavia cutleri 393 ChEMBL 10.1021/jm980511k 10.7270/Q2P26ZT4 9857089 Thomas, JB; Fall, MJ; Cooper, JB; Rothman, RB; Mascarella, SW; Xu, H; Partilla, JS; Dersch, CM; McCullough, KB; Cantrell, BE; Zimmerman, DM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102710 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102710&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9804952 103999146 CHEMBL10986 ZINC04424128 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50055080 C[C@@H]1CN(C\C=C\c2ccccc2)CC[C@]1(C)c1cccc(O)c1 InChI=1S/C22H27NO/c1-18-17-23(14-7-10-19-8-4-3-5-9-19)15-13-22(18,2)20-11-6-12-21(24)16-20/h3-12,16,18,24H,13-15,17H2,1-2H3/b10-7+/t18-,22+/m1/s1 SUIRCGLIUIROIR-FIHPSEJCSA-N 50291970 3-[(3S,4S)-3,4-Dimethyl-1-((E)-3-phenyl-allyl)-piperidin-4-yl]-phenol::CHEMBL150052 Mu-type opioid receptor Cavia cutleri 0.740000 ChEMBL 10.1021/jm980511k 10.7270/Q2P26ZT4 9857089 Thomas, JB; Fall, MJ; Cooper, JB; Rothman, RB; Mascarella, SW; Xu, H; Partilla, JS; Dersch, CM; McCullough, KB; Cantrell, BE; Zimmerman, DM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291970 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291970&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44365777 104133522 CHEMBL150052 ZINC27559837 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50055083 CC1CN(C[C@H](Cc2ccccc2)NC(=O)CCc2ccc(O)cc2)CCC1(C)c1cccc(O)c1 InChI=1S/C31H38N2O3/c1-23-21-33(18-17-31(23,2)26-9-6-10-29(35)20-26)22-27(19-25-7-4-3-5-8-25)32-30(36)16-13-24-11-14-28(34)15-12-24/h3-12,14-15,20,23,27,34-35H,13,16-19,21-22H2,1-2H3,(H,32,36)/t23?,27-,31?/m0/s1 SMGWBMWVMICQEZ-NXYCWYFDSA-N 50291972 CHEMBL148843::N-{(S)-1-Benzyl-2-[4-(3-hydroxy-phenyl)-3,4-dimethyl-piperidin-1-yl]-ethyl}-3-(4-hydroxy-phenyl)-propionamide Mu-type opioid receptor Cavia cutleri 9.6 ChEMBL 10.1021/jm980511k 10.7270/Q2P26ZT4 9857089 Thomas, JB; Fall, MJ; Cooper, JB; Rothman, RB; Mascarella, SW; Xu, H; Partilla, JS; Dersch, CM; McCullough, KB; Cantrell, BE; Zimmerman, DM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291972 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291972&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44365779 104133524 CHEMBL148843 ZINC27560977 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50055085 CCC(C)[C@@H](CN1CCC(C)(C(C)C1)c1cccc(O)c1)NC(=O)CCc1ccc(O)cc1 InChI=1S/C28H40N2O3/c1-5-20(2)26(29-27(33)14-11-22-9-12-24(31)13-10-22)19-30-16-15-28(4,21(3)18-30)23-7-6-8-25(32)17-23/h6-10,12-13,17,20-21,26,31-32H,5,11,14-16,18-19H2,1-4H3,(H,29,33)/t20?,21?,26-,28?/m1/s1 IZLUVSQTZJGTNY-YPOXPZTFSA-N 50291973 3-(4-Hydroxy-phenyl)-N-{(S)-1-[4-(3-hydroxy-phenyl)-3,4-dimethyl-piperidin-1-ylmethyl]-2-methyl-butyl}-propionamide::CHEMBL151243 Mu-type opioid receptor Cavia cutleri 421 ChEMBL 10.1021/jm980511k 10.7270/Q2P26ZT4 9857089 Thomas, JB; Fall, MJ; Cooper, JB; Rothman, RB; Mascarella, SW; Xu, H; Partilla, JS; Dersch, CM; McCullough, KB; Cantrell, BE; Zimmerman, DM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291973 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291973&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44365660 104133525 CHEMBL151243 ZINC38151880 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50055091 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2[C@@H]4Oc6c7c(C[C@H]8N(CC9CC9)CC[C@@]47[C@@]8(O)Cc2c1C[C@@]35O)ccc6O InChI=1S/C40H43N3O6/c44-25-7-5-21-13-27-39(46)15-23-24-16-40(47)28-14-22-6-8-26(45)34-30(22)38(40,10-12-43(28)18-20-3-4-20)36(49-34)32(24)41-31(23)35-37(39,29(21)33(25)48-35)9-11-42(27)17-19-1-2-19/h5-8,19-20,27-28,35-36,41,44-47H,1-4,9-18H2/t27-,28-,35+,36+,37+,38+,39-,40-/m1/s1 APSUXPSYBJVPPS-YAUKWVCOSA-N 82551 C18130::CAS_105618-26-6::NOR-BNI (HCI)2::NORBNI Mu-type opioid receptor Cavia cutleri 17 ChEMBL 10.1021/jm980511k 10.7270/Q2P26ZT4 9857089 Thomas, JB; Fall, MJ; Cooper, JB; Rothman, RB; Mascarella, SW; Xu, H; Partilla, JS; Dersch, CM; McCullough, KB; Cantrell, BE; Zimmerman, DM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82551&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5480230 136350521 C18130 ZINC03995590 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50055092 CC1CN(C[C@@H](NC(=O)CCc2ccc(O)cc2)C2CCCCC2)CCC1(C)c1cccc(O)c1 InChI=1S/C30H42N2O3/c1-22-20-32(18-17-30(22,2)25-9-6-10-27(34)19-25)21-28(24-7-4-3-5-8-24)31-29(35)16-13-23-11-14-26(33)15-12-23/h6,9-12,14-15,19,22,24,28,33-34H,3-5,7-8,13,16-18,20-21H2,1-2H3,(H,31,35)/t22?,28-,30?/m1/s1 DUXFPSHFWAWGFG-YNUMGSQSSA-N 50291974 CHEMBL359088::N-{(S)-1-Cyclohexyl-2-[4-(3-hydroxy-phenyl)-3,4-dimethyl-piperidin-1-yl]-ethyl}-3-(4-hydroxy-phenyl)-propionamide Mu-type opioid receptor Cavia cutleri 234 ChEMBL 10.1021/jm980511k 10.7270/Q2P26ZT4 9857089 Thomas, JB; Fall, MJ; Cooper, JB; Rothman, RB; Mascarella, SW; Xu, H; Partilla, JS; Dersch, CM; McCullough, KB; Cantrell, BE; Zimmerman, DM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291974&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44365674 104133526 CHEMBL359088 ZINC27564595 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50055095 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1 DQCKKXVULJGBQN-XFWGSAIBSA-N 60212 (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::MLS000069607::NALTREXONE HYDROCHLORIDE::SMR000058767::US10988481, Compound NTX::US9107954, naltrexone::cid_5485201 Mu-type opioid receptor Cavia cutleri 1.4 ChEMBL 10.1021/jm980511k 10.7270/Q2P26ZT4 9857089 Thomas, JB; Fall, MJ; Cooper, JB; Rothman, RB; Mascarella, SW; Xu, H; Partilla, JS; Dersch, CM; McCullough, KB; Cantrell, BE; Zimmerman, DM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60212&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5360515 252639834 DB00704 C07253 ZINC00001773 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50055151 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2[C@@H]4Oc6c7c(C[C@H]8N(CC9CC9)CC[C@@]47[C@@]8(O)Cc2c1C[C@@]35O)ccc6O InChI=1S/C40H43N3O6/c44-25-7-5-21-13-27-39(46)15-23-24-16-40(47)28-14-22-6-8-26(45)34-30(22)38(40,10-12-43(28)18-20-3-4-20)36(49-34)32(24)41-31(23)35-37(39,29(21)33(25)48-35)9-11-42(27)17-19-1-2-19/h5-8,19-20,27-28,35-36,41,44-47H,1-4,9-18H2/t27-,28-,35+,36+,37+,38+,39-,40-/m1/s1 APSUXPSYBJVPPS-YAUKWVCOSA-N 82551 C18130::CAS_105618-26-6::NOR-BNI (HCI)2::NORBNI Mu-type opioid receptor Cavia cutleri 47 ChEMBL 10.1021/jm980511k 10.7270/Q2P26ZT4 9857089 Thomas, JB; Fall, MJ; Cooper, JB; Rothman, RB; Mascarella, SW; Xu, H; Partilla, JS; Dersch, CM; McCullough, KB; Cantrell, BE; Zimmerman, DM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82551&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5480230 136350521 C18130 ZINC03995590 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50055161 C[C@@H]1CN(C\C=C\c2ccccc2)CC[C@]1(C)c1cccc(O)c1 InChI=1S/C22H27NO/c1-18-17-23(14-7-10-19-8-4-3-5-9-19)15-13-22(18,2)20-11-6-12-21(24)16-20/h3-12,16,18,24H,13-15,17H2,1-2H3/b10-7+/t18-,22+/m1/s1 SUIRCGLIUIROIR-FIHPSEJCSA-N 50291970 3-[(3S,4S)-3,4-Dimethyl-1-((E)-3-phenyl-allyl)-piperidin-4-yl]-phenol::CHEMBL150052 Mu-type opioid receptor Cavia cutleri 0.039000 ChEMBL 10.1021/jm980511k 10.7270/Q2P26ZT4 9857089 Thomas, JB; Fall, MJ; Cooper, JB; Rothman, RB; Mascarella, SW; Xu, H; Partilla, JS; Dersch, CM; McCullough, KB; Cantrell, BE; Zimmerman, DM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291970 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291970&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44365777 104133522 CHEMBL150052 ZINC27559837 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057893 CC1(C)SSC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(O)=O InChI=1S/C26H32N4O6S2/c1-26(2)21(25(35)36)30-23(33)19(13-15-6-4-3-5-7-15)28-24(34)20(14-37-38-26)29-22(32)18(27)12-16-8-10-17(31)11-9-16/h3-11,18-21,31H,12-14,27H2,1-2H3,(H,28,34)(H,29,32)(H,30,33)(H,35,36)/t18-,19-,20-,21+/m0/s1 BLNPATOSLCUUSL-XSDIEEQYSA-N 50000655 (4R,7S,10R)-10-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL39192 Mu-type opioid receptor Cavia cutleri 107 ChEMBL 10.1021/jm00101a030 10.7270/Q2N0174K 1333014 Mosberg, HI; Kroona, HB University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000655 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000655&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44285718 103915203 CHEMBL39192 ZINC26648527 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057894 CN1CC[C@@]23[C@@H](Oc4c2cccc4O)C(=O)CC[C@H]3C1 InChI=1S/C16H19NO3/c1-17-8-7-16-10(9-17)5-6-13(19)15(16)20-14-11(16)3-2-4-12(14)18/h2-4,10,15,18H,5-9H2,1H3/t10-,15-,16-/m0/s1 FYULEOKOSVDLQX-HNHYXYPQSA-N 50037133 (4aR,7aR,12bS)-9-Hydroxy-3-methyl-2,3,4,4a,5,6-hexahydro-1H-8-oxa-3-aza-benzo[d]fluoren-7-one::CHEMBL324418 Mu-type opioid receptor Cavia cutleri 7.8 ChEMBL 10.1021/jm00045a017 10.7270/Q2PK0F6R 7932535 Cheng, CY; Hsin, LW; Tsai, MC; Schmidt, WK; Smith, C; Tam, SW National Taiwan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037133 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037133&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336449 103944711 CHEMBL324418 ZINC13738597 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057900 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 38 ChEMBL 10.1021/jm00045a017 10.7270/Q2PK0F6R 7932535 Cheng, CY; Hsin, LW; Tsai, MC; Schmidt, WK; Smith, C; Tam, SW National Taiwan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057903 O[C@H]1CC[C@H]2CN(CC3CC3)CC[C@]22[C@H]1Oc1c2cccc1O InChI=1S/C19H25NO3/c21-15-3-1-2-14-17(15)23-18-16(22)7-6-13-11-20(10-12-4-5-12)9-8-19(13,14)18/h1-3,12-13,16,18,21-22H,4-11H2/t13-,16-,18-,19-/m0/s1 KTXMLKWFHNEBJM-FDARSICLSA-N 50037131 (4aR,7S,7aR,12bS)-3-Cyclopropylmethyl-2,3,4,4a,5,6,7,7a-octahydro-1H-8-oxa-3-aza-benzo[d]fluorene-7,9-diol::CHEMBL319236 Mu-type opioid receptor Cavia cutleri 1.4 ChEMBL 10.1021/jm00045a017 10.7270/Q2PK0F6R 7932535 Cheng, CY; Hsin, LW; Tsai, MC; Schmidt, WK; Smith, C; Tam, SW National Taiwan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037131&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10448420 103944709 CHEMBL319236 ZINC13738595 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057907 COc1cccc2c1O[C@H]1[C@@H](O)CC[C@H]3CN(CC4CC4)CC[C@]213 InChI=1S/C20H27NO3/c1-23-17-4-2-3-15-18(17)24-19-16(22)8-7-14-12-21(11-13-5-6-13)10-9-20(14,15)19/h2-4,13-14,16,19,22H,5-12H2,1H3/t14-,16-,19-,20-/m0/s1 IILIVCVVZSPCRP-QHERXFFYSA-N 50037137 (4aR,7S,7aR,12bS)-3-Cyclopropylmethyl-9-methoxy-2,3,4,4a,5,6,7,7a-octahydro-1H-8-oxa-3-aza-benzo[d]fluoren-7-ol::CHEMBL106085 Mu-type opioid receptor Cavia cutleri 29 ChEMBL 10.1021/jm00045a017 10.7270/Q2PK0F6R 7932535 Cheng, CY; Hsin, LW; Tsai, MC; Schmidt, WK; Smith, C; Tam, SW National Taiwan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037137 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037137&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10246015 103944715 CHEMBL106085 ZINC13738594 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057908 O[C@@H]1CC[C@@H]2CN(CC3CC3)CC[C@]22[C@H]1Oc1c2cccc1O InChI=1S/C19H25NO3/c21-15-3-1-2-14-17(15)23-18-16(22)7-6-13-11-20(10-12-4-5-12)9-8-19(13,14)18/h1-3,12-13,16,18,21-22H,4-11H2/t13-,16-,18+,19+/m1/s1 KTXMLKWFHNEBJM-OLQIXAPSSA-N 50037130 (4aS,7R,7aR,12bS)-3-Cyclopropylmethyl-2,3,4,4a,5,6,7,7a-octahydro-1H-8-oxa-3-aza-benzo[d]fluorene-7,9-diol::CHEMBL323281 Mu-type opioid receptor Cavia cutleri 3.9 ChEMBL 10.1021/jm00045a017 10.7270/Q2PK0F6R 7932535 Cheng, CY; Hsin, LW; Tsai, MC; Schmidt, WK; Smith, C; Tam, SW National Taiwan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037130&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336430 103944708 CHEMBL323281 ZINC26843427 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057909 CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23-,24-/m0/s1 MCMMCRYPQBNCPH-DVKRWUGUSA-N 50001683 13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid::7-Benzyl-10-{[3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL294616::DPDPE Mu-type opioid receptor Cavia cutleri 810 ChEMBL 10.1021/jm00101a030 10.7270/Q2N0174K 1333014 Mosberg, HI; Kroona, HB University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001683&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299404 103916113 CHEMBL294616 ZINC27520031 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057914 Oc1cccc2c1O[C@H]1C(=O)CC[C@@H]3CN(CC4CC4)CC[C@]213 InChI=1S/C19H23NO3/c21-15-3-1-2-14-17(15)23-18-16(22)7-6-13-11-20(10-12-4-5-12)9-8-19(13,14)18/h1-3,12-13,18,21H,4-11H2/t13-,18+,19+/m1/s1 XPJMFYKZWMSEIT-VMDGZTHMSA-N 50037136 (4aS,7aR,12bS)-3-Cyclopropylmethyl-9-hydroxy-2,3,4,4a,5,6-hexahydro-1H-8-oxa-3-aza-benzo[d]fluoren-7-one::CHEMBL106910 Mu-type opioid receptor Cavia cutleri 19 ChEMBL 10.1021/jm00045a017 10.7270/Q2PK0F6R 7932535 Cheng, CY; Hsin, LW; Tsai, MC; Schmidt, WK; Smith, C; Tam, SW National Taiwan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037136&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10041278 103944714 CHEMBL106910 ZINC13738593 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057915 COc1cccc2c1O[C@H]1C(=O)CC[C@H]3CN(CC4CC4)CC[C@]213 InChI=1S/C20H25NO3/c1-23-17-4-2-3-15-18(17)24-19-16(22)8-7-14-12-21(11-13-5-6-13)10-9-20(14,15)19/h2-4,13-14,19H,5-12H2,1H3/t14-,19-,20-/m0/s1 OTEUCXIVYSDXSR-GKCIPKSASA-N 50037132 (4aR,7aR,12bS)-3-Cyclopropylmethyl-9-methoxy-2,3,4,4a,5,6-hexahydro-1H-8-oxa-3-aza-benzo[d]fluoren-7-one::CHEMBL321289 Mu-type opioid receptor Cavia cutleri 76 ChEMBL 10.1021/jm00045a017 10.7270/Q2PK0F6R 7932535 Cheng, CY; Hsin, LW; Tsai, MC; Schmidt, WK; Smith, C; Tam, SW National Taiwan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037132&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10065022 103944710 CHEMBL321289 ZINC13738591 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057916 Oc1cccc2c1O[C@H]1C(=O)CC[C@H]3CN(CC4CC4)CC[C@]213 InChI=1S/C19H23NO3/c21-15-3-1-2-14-17(15)23-18-16(22)7-6-13-11-20(10-12-4-5-12)9-8-19(13,14)18/h1-3,12-13,18,21H,4-11H2/t13-,18-,19-/m0/s1 XPJMFYKZWMSEIT-AGRHKRQWSA-N 50037135 (4aR,7aR,12bS)-3-Cyclopropylmethyl-9-hydroxy-2,3,4,4a,5,6-hexahydro-1H-8-oxa-3-aza-benzo[d]fluoren-7-one::CHEMBL106027 Mu-type opioid receptor Cavia cutleri 0.25 ChEMBL 10.1021/jm00045a017 10.7270/Q2PK0F6R 7932535 Cheng, CY; Hsin, LW; Tsai, MC; Schmidt, WK; Smith, C; Tam, SW National Taiwan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037135 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037135&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10267592 103944713 CHEMBL106027 ZINC13738592 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057918 CC1(C)SSC[C@@H](NC(=O)[C@@H]2NCC[C@@H]2c2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(O)=O InChI=1S/C28H34N4O6S2/c1-28(2)23(27(37)38)32-24(34)20(14-16-6-4-3-5-7-16)30-25(35)21(15-39-40-28)31-26(36)22-19(12-13-29-22)17-8-10-18(33)11-9-17/h3-11,19-23,29,33H,12-15H2,1-2H3,(H,30,35)(H,31,36)(H,32,34)(H,37,38)/t19-,20+,21-,22-,23-/m1/s1 ZATPZTVNZBDUOD-PFDCGNQRSA-N 50001685 7-Benzyl-10-{[3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL2370869 Mu-type opioid receptor Cavia cutleri 10000 ChEMBL 10.1021/jm00101a030 10.7270/Q2N0174K 1333014 Mosberg, HI; Kroona, HB University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001685 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001685&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73351608 103916115 CHEMBL2370869 ZINC27520035 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057920 Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1 UZHSEJADLWPNLE-GRGSLBFTSA-N 50000788 (morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(naloxone) 4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::(naloxone)4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::(naloxone)4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one (naloxone)::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one( Naloxone)::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(Naxolone)::4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(naloxone)C2H2O4::Analog of 14-(Arylhydroxyamino)codeinone::NALOXONE::NARCAN::SUBOXONE::[17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydroxymorphinan-6-one Mu-type opioid receptor Cavia cutleri 1.1 ChEMBL 10.1021/jm00045a017 10.7270/Q2PK0F6R 7932535 Cheng, CY; Hsin, LW; Tsai, MC; Schmidt, WK; Smith, C; Tam, SW National Taiwan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000788&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5284596 103915330 7459 DB01183 1676 C07252 ZINC00389747 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057922 Oc1cccc2c1O[C@H]1CCC[C@H]3CN(CC4CC4)CC[C@]213 InChI=1S/C19H25NO2/c21-16-5-2-4-15-18(16)22-17-6-1-3-14-12-20(11-13-7-8-13)10-9-19(14,15)17/h2,4-5,13-14,17,21H,1,3,6-12H2/t14-,17-,19-/m0/s1 SQZBAUUHDXMUTO-FNHZYXHNSA-N 50037134 (+)-trans-3-Cyclopropylmethyl-2,3,4,4aalpha,5,6,7,7aalpha-octahydro-1H-benzo[4,5]furo[3,2-e]isoquinolin-9-ol::(+/-)-trans-3-Cyclopropylmethyl-2,3,4,4aalpha,5,6,7,7aalpha-octahydro-1H-benzo[4,5]furo[3,2-e]isoquinolin-9-ol::(-)-trans-3-Cyclopropylmethyl-2,3,4,4aalpha,5,6,7,7aalpha-octahydro-1H-benzo[4,5]furo[3,2-e]isoquinolin-9-ol::(4aR,7aS,12bS)-3-Cyclopropylmethyl-2,3,4,4a,5,6,7,7a-octahydro-1H-8-oxa-3-aza-benzo[d]fluoren-9-ol::CHEMBL104042 Mu-type opioid receptor Cavia cutleri 0.57 ChEMBL 10.1021/jm00045a017 10.7270/Q2PK0F6R 7932535 Cheng, CY; Hsin, LW; Tsai, MC; Schmidt, WK; Smith, C; Tam, SW National Taiwan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037134 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037134&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336365 103944712 CHEMBL104042 ZINC13738590 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50058006 COC(=O)C(=C)COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2ccccc2c1C[C@@]35O InChI=1S/C31H32N2O5/c1-17(29(34)36-2)16-37-23-10-9-19-13-24-31(35)14-21-20-5-3-4-6-22(20)32-26(21)28-30(31,25(19)27(23)38-28)11-12-33(24)15-18-7-8-18/h3-6,9-10,18,24,28,32,35H,1,7-8,11-16H2,2H3/t24-,28+,30+,31-/m1/s1 CAAHFTSIXKSWPY-FSYRHIKOSA-N 50001703 CHEMBL344420::methyl 2-[22-cyclopropylmethyl-2-hydroxy-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaen-16-yloxymethyl]acrylate Mu-type opioid receptor Cavia cutleri 96 ChEMBL 10.1021/jm00102a012 10.7270/Q27S7PCK 1335078 Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001703 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001703&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10481516 103916118 CHEMBL344420 ZINC13730996 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50058007 Oc1ccc2C[C@H]3N(CC4CC4)CCC45C(Oc1c24)c1[nH]c2ccccc2c1CC35O InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1 WIYUZYBFCWCCQJ-XEWUMVRVSA-N 21864 (21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.0^{1,13}.0^{2,21}.0^{4,12}.0^{5,10}.0^{19,25}]pentacosa-4(12),5,7,9,15,17,19(25)-heptaene-2,16-diol::(8R)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol::NALTRINDOLE::[3H]-naltrindole Mu-type opioid receptor Cavia cutleri 37 ChEMBL 10.1021/jm00102a012 10.7270/Q27S7PCK 1335078 Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21864&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3034754 49700969 ZINC62153992 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50059074 CC1(C)SSC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccc(F)cc2)C(=O)N[C@@H]1C(O)=O InChI=1S/C26H31FN4O6S2/c1-26(2)21(25(36)37)31-23(34)19(12-15-3-7-16(27)8-4-15)29-24(35)20(13-38-39-26)30-22(33)18(28)11-14-5-9-17(32)10-6-14/h3-10,18-21,32H,11-13,28H2,1-2H3,(H,29,35)(H,30,33)(H,31,34)(H,36,37)/t18-,19-,20-,21+/m0/s1 MEIXAGSKAIOYBG-XSDIEEQYSA-N 50000659 10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-(4-fluoro-benzyl)-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL290005 Mu-type opioid receptor Cavia cutleri 161 ChEMBL 10.1021/jm00087a006 10.7270/Q23T9HVN 1315870 Heyl, DL; Mosberg, HI University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000659 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000659&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15659189 103915207 CHEMBL290005 ZINC29330344 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50059078 CC(C)(C)c1ccc(C[C@@H]2NC(=O)[C@H](CSSC(C)(C)[C@H](NC2=O)C(O)=O)NC(=O)[C@@H](N)Cc2ccc(O)cc2)cc1 InChI=1S/C30H40N4O6S2/c1-29(2,3)19-10-6-18(7-11-19)15-22-26(37)34-24(28(39)40)30(4,5)42-41-16-23(27(38)32-22)33-25(36)21(31)14-17-8-12-20(35)13-9-17/h6-13,21-24,35H,14-16,31H2,1-5H3,(H,32,38)(H,33,36)(H,34,37)(H,39,40)/t21-,22-,23-,24+/m0/s1 GZVHKYLTFQBPMK-NEWJYFPISA-N 50000654 10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-(4-tert-butyl-benzyl)-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL290968 Mu-type opioid receptor Cavia cutleri 10000 ChEMBL 10.1021/jm00087a006 10.7270/Q23T9HVN 1315870 Heyl, DL; Mosberg, HI University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000654 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000654&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15659194 103915202 CHEMBL290968 ZINC29326659 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50059083 CC1(C)SSC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H]1C(O)=O InChI=1S/C26H32N4O6S2/c1-26(2)21(25(35)36)30-23(33)19(13-15-6-4-3-5-7-15)28-24(34)20(14-37-38-26)29-22(32)18(27)12-16-8-10-17(31)11-9-16/h3-11,18-21,31H,12-14,27H2,1-2H3,(H,28,34)(H,29,32)(H,30,33)(H,35,36)/t18-,19-,20-,21+/m0/s1 BLNPATOSLCUUSL-XSDIEEQYSA-N 50000655 (4R,7S,10R)-10-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL39192 Mu-type opioid receptor Cavia cutleri 107 ChEMBL 10.1021/jm00087a006 10.7270/Q23T9HVN 1315870 Heyl, DL; Mosberg, HI University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000655 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000655&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44285718 103915203 CHEMBL39192 ZINC26648527 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50059085 CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23-,24-/m0/s1 MCMMCRYPQBNCPH-DVKRWUGUSA-N 50001683 13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid::7-Benzyl-10-{[3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL294616::DPDPE Mu-type opioid receptor Cavia cutleri 810 ChEMBL 10.1021/jm00087a006 10.7270/Q23T9HVN 1315870 Heyl, DL; Mosberg, HI University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001683&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299404 103916113 CHEMBL294616 ZINC27520031 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50059088 CC1(C)SSC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2F)C(=O)N[C@@H]1C(O)=O InChI=1S/C26H31FN4O6S2/c1-26(2)21(25(36)37)31-23(34)19(12-15-5-3-4-6-17(15)27)29-24(35)20(13-38-39-26)30-22(33)18(28)11-14-7-9-16(32)10-8-14/h3-10,18-21,32H,11-13,28H2,1-2H3,(H,29,35)(H,30,33)(H,31,34)(H,36,37)/t18-,19-,20-,21+/m0/s1 ZIGFHLXHJJNVOW-XSDIEEQYSA-N 50000656 10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-(2-fluoro-benzyl)-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL38578 Mu-type opioid receptor Cavia cutleri 92 ChEMBL 10.1021/jm00087a006 10.7270/Q23T9HVN 1315870 Heyl, DL; Mosberg, HI University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000656 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000656&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15659190 103915204 CHEMBL38578 ZINC29329408 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50059089 CC1(C)SSC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccc(Cl)cc2)C(=O)N[C@@H]1C(O)=O InChI=1S/C26H31ClN4O6S2/c1-26(2)21(25(36)37)31-23(34)19(12-15-3-7-16(27)8-4-15)29-24(35)20(13-38-39-26)30-22(33)18(28)11-14-5-9-17(32)10-6-14/h3-10,18-21,32H,11-13,28H2,1-2H3,(H,29,35)(H,30,33)(H,31,34)(H,36,37)/t18-,19-,20-,21+/m0/s1 SCYKXJYGJUFAIE-XSDIEEQYSA-N 50000650 10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-(4-chloro-benzyl)-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL39211 Mu-type opioid receptor Cavia cutleri 327 ChEMBL 10.1021/jm00087a006 10.7270/Q23T9HVN 1315870 Heyl, DL; Mosberg, HI University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000650 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000650&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15659192 103915198 CHEMBL39211 ZINC29335598 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50059090 CC1(C)SSC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2cccc(F)c2)C(=O)N[C@@H]1C(O)=O InChI=1S/C26H31FN4O6S2/c1-26(2)21(25(36)37)31-23(34)19(12-15-4-3-5-16(27)10-15)29-24(35)20(13-38-39-26)30-22(33)18(28)11-14-6-8-17(32)9-7-14/h3-10,18-21,32H,11-13,28H2,1-2H3,(H,29,35)(H,30,33)(H,31,34)(H,36,37)/t18-,19-,20-,21+/m0/s1 WLPHUDYTEIUFDX-XSDIEEQYSA-N 50000652 10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-(3-fluoro-benzyl)-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL289355 Mu-type opioid receptor Cavia cutleri 56 ChEMBL 10.1021/jm00087a006 10.7270/Q23T9HVN 1315870 Heyl, DL; Mosberg, HI University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000652 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000652&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15659191 103915200 CHEMBL289355 ZINC29336059 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50059091 Cc1ccc(C[C@@H]2NC(=O)[C@H](CSSC(C)(C)[C@H](NC2=O)C(O)=O)NC(=O)[C@@H](N)Cc2ccc(O)cc2)cc1 InChI=1S/C27H34N4O6S2/c1-15-4-6-17(7-5-15)13-20-24(34)31-22(26(36)37)27(2,3)39-38-14-21(25(35)29-20)30-23(33)19(28)12-16-8-10-18(32)11-9-16/h4-11,19-22,32H,12-14,28H2,1-3H3,(H,29,35)(H,30,33)(H,31,34)(H,36,37)/t19-,20-,21-,22+/m0/s1 ZFSJYJQUEXPSJS-MYGLTJDJSA-N 50000658 10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-3,3-dimethyl-7-(4-methyl-benzyl)-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL39562 Mu-type opioid receptor Cavia cutleri 1750 ChEMBL 10.1021/jm00087a006 10.7270/Q23T9HVN 1315870 Heyl, DL; Mosberg, HI University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000658 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000658&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15659193 103915206 CHEMBL39562 ZINC29327796 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50059096 CC1(C)SSC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H]1C(O)=O InChI=1S/C26H32N4O7S2/c1-26(2)21(25(36)37)30-23(34)19(12-15-5-9-17(32)10-6-15)28-24(35)20(13-38-39-26)29-22(33)18(27)11-14-3-7-16(31)8-4-14/h3-10,18-21,31-32H,11-13,27H2,1-2H3,(H,28,35)(H,29,33)(H,30,34)(H,36,37)/t18-,19-,20-,21+/m0/s1 RIOTZSPUJMBYRV-XSDIEEQYSA-N 50000653 10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-(4-hydroxy-benzyl)-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL36845 Mu-type opioid receptor Cavia cutleri 3450 ChEMBL 10.1021/jm00087a006 10.7270/Q23T9HVN 1315870 Heyl, DL; Mosberg, HI University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000653 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000653&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15659195 103915201 CHEMBL36845 ZINC29323174 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50059097 CC1(C)SSC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccc(cc2)[N+]([O-])=O)C(=O)N[C@@H]1C(O)=O InChI=1S/C26H31N5O8S2/c1-26(2)21(25(36)37)30-23(34)19(12-15-3-7-16(8-4-15)31(38)39)28-24(35)20(13-40-41-26)29-22(33)18(27)11-14-5-9-17(32)10-6-14/h3-10,18-21,32H,11-13,27H2,1-2H3,(H,28,35)(H,29,33)(H,30,34)(H,36,37)/t18-,19-,20-,21+/m0/s1 BPHSABZCJLJRST-XSDIEEQYSA-N 50000657 10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-3,3-dimethyl-7-(4-nitro-benzyl)-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL37158 Mu-type opioid receptor Cavia cutleri 137 ChEMBL 10.1021/jm00087a006 10.7270/Q23T9HVN 1315870 Heyl, DL; Mosberg, HI University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000657 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000657&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15659197 103915205 CHEMBL37158 ZINC29323170 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50059098 CC1(C)SSC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2cccc(O)c2)C(=O)N[C@@H]1C(O)=O InChI=1S/C26H32N4O7S2/c1-26(2)21(25(36)37)30-23(34)19(12-15-4-3-5-17(32)10-15)28-24(35)20(13-38-39-26)29-22(33)18(27)11-14-6-8-16(31)9-7-14/h3-10,18-21,31-32H,11-13,27H2,1-2H3,(H,28,35)(H,29,33)(H,30,34)(H,36,37)/t18-,19-,20-,21+/m0/s1 QRZQJIHCHBMRCN-XSDIEEQYSA-N 50000651 10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-(3-hydroxy-benzyl)-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL39647 Mu-type opioid receptor Cavia cutleri 3400 ChEMBL 10.1021/jm00087a006 10.7270/Q23T9HVN 1315870 Heyl, DL; Mosberg, HI University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000651 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000651&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15659196 103915199 CHEMBL39647 ZINC29324996 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50058014 COC(=O)C(=C)COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2[C@@H]4Oc6c7c(C[C@H]8N(CC9CC9)CC[C@@]47[C@@]8(O)Cc2c1C[C@@]35O)ccc6OCC(=C)C(=O)OC InChI=1S/C50H55N3O10/c1-25(45(54)58-3)23-60-33-11-9-29-17-35-49(56)19-31-32-20-50(57)36-18-30-10-12-34(61-24-26(2)46(55)59-4)42-38(30)48(50,14-16-53(36)22-28-7-8-28)44(63-42)40(32)51-39(31)43-47(49,37(29)41(33)62-43)13-15-52(35)21-27-5-6-27/h9-12,27-28,35-36,43-44,51,56-57H,1-2,5-8,13-24H2,3-4H3/t35-,36-,43+,44+,47+,48+,49-,50-/m1/s1 OENOSKJZARWWAW-GULDIMLMSA-N 50001715 CHEMBL407685::Norbinaltorphimine3,3'-diether Mu-type opioid receptor Cavia cutleri 47 ChEMBL 10.1021/jm00102a012 10.7270/Q27S7PCK 1335078 Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001715 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001715&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10350630 103916130 CHEMBL407685 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50058015 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1 DQCKKXVULJGBQN-XFWGSAIBSA-N 60212 (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::MLS000069607::NALTREXONE HYDROCHLORIDE::SMR000058767::US10988481, Compound NTX::US9107954, naltrexone::cid_5485201 Mu-type opioid receptor Cavia cutleri 0.730000 ChEMBL 10.1021/jm00102a012 10.7270/Q27S7PCK 1335078 Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60212&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5360515 252639834 DB00704 C07253 ZINC00001773 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50058019 COC(=O)C(=C)COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@H](O)CC[C@@]35O InChI=1S/C25H31NO6/c1-14(23(28)30-2)13-31-18-6-5-16-11-19-25(29)8-7-17(27)22-24(25,20(16)21(18)32-22)9-10-26(19)12-15-3-4-15/h5-6,15,17,19,22,27,29H,1,3-4,7-13H2,2H3/t17-,19-,22+,24+,25-/m1/s1 UKONENWNLPVMFY-SZSHLTAVSA-N 50001716 CHEMBL140044::methyl 2-[4-cyclopropylmethyl-14,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-trien-10-yloxymethyl]acrylate Mu-type opioid receptor Cavia cutleri 2.8 ChEMBL 10.1021/jm00102a012 10.7270/Q27S7PCK 1335078 Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001716 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001716&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10321082 103916131 CHEMBL140044 ZINC13730990 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50058020 COC(=O)C(C)COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C25H31NO6/c1-14(23(28)30-2)13-31-18-6-5-16-11-19-25(29)8-7-17(27)22-24(25,20(16)21(18)32-22)9-10-26(19)12-15-3-4-15/h5-6,14-15,19,22,29H,3-4,7-13H2,1-2H3/t14?,19-,22+,24+,25-/m1/s1 YZZFUHJSMKNVJW-PCMDLLDESA-N 50001706 CHEMBL140855::methyl 3-[4-cyclopropylmethyl-17-hydroxy-14-oxo-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-trien-10-yloxy]-2-methylpropanoate Mu-type opioid receptor Cavia cutleri 840 ChEMBL 10.1021/jm00102a012 10.7270/Q27S7PCK 1335078 Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001706 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001706&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10455974 103916121 CHEMBL140855 ZINC13730987 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50058022 COC(=O)C(=C)CO[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45 InChI=1S/C25H31NO6/c1-14(23(28)30-2)13-31-18-7-8-25(29)19-11-16-5-6-17(27)21-20(16)24(25,22(18)32-21)9-10-26(19)12-15-3-4-15/h5-6,15,18-19,22,27,29H,1,3-4,7-13H2,2H3/t18-,19-,22+,24+,25-/m1/s1 ZLKXBHFJETUNMU-WXIYZNRCSA-N 50000790 CHEMBL76023::methyl 2-[4-cyclopropylmethyl-10,17-dihydroxy-(13R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-trien-14-yloxymethyl]acrylate::methyl 2-[4-cyclopropylmethyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-yloxymethyl]acrylate Mu-type opioid receptor Cavia cutleri 2.5 ChEMBL 10.1021/jm00102a012 10.7270/Q27S7PCK 1335078 Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000790&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10026312 103915332 CHEMBL76023 ZINC13724983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50058027 COC(=O)C(=C)COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C25H29NO6/c1-14(23(28)30-2)13-31-18-6-5-16-11-19-25(29)8-7-17(27)22-24(25,20(16)21(18)32-22)9-10-26(19)12-15-3-4-15/h5-6,15,19,22,29H,1,3-4,7-13H2,2H3/t19-,22+,24+,25-/m1/s1 CLLKOUBFCBEXLC-CKZJNZIISA-N 50001705 CHEMBL343167::methyl 2-[4-cyclopropylmethyl-17-hydroxy-14-oxo-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-trien-10-yloxymethyl]acrylate Mu-type opioid receptor Cavia cutleri 1.5 ChEMBL 10.1021/jm00102a012 10.7270/Q27S7PCK 1335078 Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001705 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001705&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10455862 103916120 CHEMBL343167 ZINC13730981 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50058028 COC(=O)C(=C)COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@]1(CC[C@@]35C[C@@H]1C(C)(C)O)OC InChI=1S/C31H41NO6/c1-18(26(33)35-4)17-37-21-9-8-20-14-23-29-10-11-31(36-5,22(15-29)28(2,3)34)27-30(29,24(20)25(21)38-27)12-13-32(23)16-19-6-7-19/h8-9,19,22-23,27,34H,1,6-7,10-17H2,2-5H3/t22-,23-,27-,29-,30+,31-/m1/s1 OVZOHYBBMVIHLB-LJLNTSMHSA-N 50455774 CHEMBL2092986 Mu-type opioid receptor Cavia cutleri 1 ChEMBL 10.1021/jm00102a012 10.7270/Q27S7PCK 1335078 Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50455774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50455774&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10459444 225146690 CHEMBL2092986 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50058029 CCC12CCN(CC3(O)CC3)C(Cc3ccc(O)cc13)C2(C)C InChI=1S/C20H29NO2/c1-4-20-9-10-21(13-19(23)7-8-19)17(18(20,2)3)11-14-5-6-15(22)12-16(14)20/h5-6,12,17,22-23H,4,7-11,13H2,1-3H3 ZDXGFIXMPOUDFF-UHFFFAOYSA-N 50013388 6-Ethyl-3-(1-hydroxy-cyclopropylmethyl)-11,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::BREMAZOCINE(-)::Bremazocine::CHEMBL350384 Mu-type opioid receptor Cavia cutleri 1.8 ChEMBL 10.1021/jm00102a012 10.7270/Q27S7PCK 1335078 Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013388 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013388&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 1223 103925603 CHEMBL350384 ZINC03870315 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50058032 O[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45 InChI=1S/C20H25NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,14-15,18,22-24H,1-2,5-10H2/t14-,15-,18+,19+,20-/m1/s1 JLVNEHKORQFVQJ-PYIJOLGTSA-N 50001709 4-cyclopropylmethyl-(13R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-triene-10,14,17-triol::CHEMBL140278::CHEMBL558140::Naltrexone-6-beta-ol Mu-type opioid receptor Cavia cutleri 2.2 ChEMBL 10.1021/jm00102a012 10.7270/Q27S7PCK 1335078 Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001709 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001709&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5486554 103916124 CHEMBL140278CHEMBL558140 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50058034 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)CCC4=O)ccc5O InChI=1S/C17H19NO4/c1-18-7-6-16-13-9-2-3-10(19)14(13)22-15(16)11(20)4-5-17(16,21)12(18)8-9/h2-3,12,15,19,21H,4-8H2,1H3/t12-,15+,16+,17-/m1/s1 UQCNKQCJZOAFTQ-ISWURRPUSA-N 50001707 10,17-dihydroxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::10,17-dihydroxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(oxymorphone)::10,17-dihydroxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(xymorphone)::10,17-dihydroxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-trien-14-one::CHEMBL963::Codoxy::Combunox::Numorphan::OXYMORPHONE::Opana::Oxycet::PERCODAN-DEMI::Percocet::Percodan::Roxicet::Roxilox::Roxiprin::Tylox::Tylox-325 Mu-type opioid receptor Cavia cutleri 1.4 ChEMBL 10.1021/jm00102a012 10.7270/Q27S7PCK 1335078 Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001707 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001707&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5284604 103916122 CHEMBL963 DB01192 7094 C08019 ZINC03875483 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50058053 COC(=O)C(=C)COc1ccc2C[C@H]3N(C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C22H25NO6/c1-12(20(25)27-3)11-28-15-5-4-13-10-16-22(26)7-6-14(24)19-21(22,8-9-23(16)2)17(13)18(15)29-19/h4-5,16,19,26H,1,6-11H2,2-3H3/t16-,19+,21+,22-/m1/s1 FTRIZKVBFWUOML-JJJJLYANSA-N 50001710 CHEMBL140145::methyl 2-[17-hydroxy-4-methyl-14-oxo-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-trien-10-yloxymethyl]acrylate Mu-type opioid receptor Cavia cutleri 2.4 ChEMBL 10.1021/jm00102a012 10.7270/Q27S7PCK 1335078 Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001710 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001710&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10046467 103916125 CHEMBL140145 ZINC13730978 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50058057 Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1 UZHSEJADLWPNLE-GRGSLBFTSA-N 50000788 (morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(naloxone) 4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::(naloxone)4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::(naloxone)4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one (naloxone)::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one( Naloxone)::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(Naxolone)::4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(naloxone)C2H2O4::Analog of 14-(Arylhydroxyamino)codeinone::NALOXONE::NARCAN::SUBOXONE::[17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydroxymorphinan-6-one Mu-type opioid receptor Cavia cutleri 8.9 ChEMBL 10.1021/jm00102a012 10.7270/Q27S7PCK 1335078 Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000788&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5284596 103915330 7459 DB01183 1676 C07252 ZINC00389747 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50058059 CO[C@]12CC[C@@]3(C[C@@H]1C(C)(C)O)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45 InChI=1S/C26H35NO4/c1-23(2,29)18-13-24-8-9-26(18,30-3)22-25(24)10-11-27(14-15-4-5-15)19(24)12-16-6-7-17(28)21(31-22)20(16)25/h6-7,15,18-19,22,28-29H,4-5,8-14H2,1-3H3/t18-,19-,22-,24-,25+,26-/m1/s1 OIJXLIIMXHRJJH-KNLIIKEYSA-N 50001714 2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1S,2R,6S,14R,15R,16R)-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-16-yl]-2-propanol::2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1S,2R,6S,14R,15R,16R)-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-16-yl]-2-propanol(diprenorphine)::2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7(12),8,10-trien-16-yl]-2-propanol::CHEMBL281786::DIPRENORPHINE-HCl::Diprenorphine Mu-type opioid receptor Cavia cutleri 0.710000 ChEMBL 10.1021/jm00102a012 10.7270/Q27S7PCK 1335078 Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001714 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001714&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 443408 103916129 CHEMBL281786 C11794 ZINC04102215 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50058060 COC(=O)C(=C)CO[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(OCC(=C)C(=O)OC)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45 InChI=1S/C30H37NO8/c1-17(27(32)35-3)15-37-21-8-7-20-13-23-30(34)10-9-22(38-16-18(2)28(33)36-4)26-29(30,24(20)25(21)39-26)11-12-31(23)14-19-5-6-19/h7-8,19,22-23,26,34H,1-2,5-6,9-16H2,3-4H3/t22-,23-,26+,29+,30-/m1/s1 GVEQIUQAUJPICN-LPBXJGNBSA-N 50001712 CHEMBL143416::methyl 2-[4-cyclopropylmethyl-17-hydroxy-10-(2-methyloxycarbonylallyloxy)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-trien-14-yloxymethyl]acrylate Mu-type opioid receptor Cavia cutleri 2.8 ChEMBL 10.1021/jm00102a012 10.7270/Q27S7PCK 1335078 Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001712 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001712&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10414887 103916127 CHEMBL143416 ZINC27524097 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50058064 CCC[C@@](C)(O)[C@H]1C[C@]23C=C[C@]1(OC)[C@@H]1Oc4c5c(C[C@H]2N(C)CC[C@@]315)ccc4OCC(=C)C(=O)OC InChI=1S/C30H39NO6/c1-7-10-27(3,33)21-16-28-11-12-30(21,35-6)26-29(28)13-14-31(4)22(28)15-19-8-9-20(24(37-26)23(19)29)36-17-18(2)25(32)34-5/h8-9,11-12,21-22,26,33H,2,7,10,13-17H2,1,3-6H3/t21-,22-,26-,27-,28-,29+,30-/m1/s1 ORWZTKJMAQGECS-TVQXRLMPSA-N 50001713 CHEMBL143815::methyl 2-[19-(1-hydroxy-1-methylbutyl)-15-methoxy-3-methyl-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7(12),8,10,16-tetraen-11-yloxymethyl]acrylate Mu-type opioid receptor Cavia cutleri 0.750000 ChEMBL 10.1021/jm00102a012 10.7270/Q27S7PCK 1335078 Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001713 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001713&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10346220 103916128 CHEMBL143815 ZINC13730993 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50058065 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2[C@@H]4Oc6c7c(C[C@H]8N(CC9CC9)CC[C@@]47[C@@]8(O)Cc2c1C[C@@]35O)ccc6O InChI=1S/C40H43N3O6/c44-25-7-5-21-13-27-39(46)15-23-24-16-40(47)28-14-22-6-8-26(45)34-30(22)38(40,10-12-43(28)18-20-3-4-20)36(49-34)32(24)41-31(23)35-37(39,29(21)33(25)48-35)9-11-42(27)17-19-1-2-19/h5-8,19-20,27-28,35-36,41,44-47H,1-4,9-18H2/t27-,28-,35+,36+,37+,38+,39-,40-/m1/s1 APSUXPSYBJVPPS-YAUKWVCOSA-N 82551 C18130::CAS_105618-26-6::NOR-BNI (HCI)2::NORBNI Mu-type opioid receptor Cavia cutleri 18 ChEMBL 10.1021/jm00102a012 10.7270/Q27S7PCK 1335078 Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82551&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5480230 136350521 C18130 ZINC03995590 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50058066 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)N(CC=C)CC=C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C69H111N21O13/c1-7-34-89(35-8-2)54(39-45-26-28-46(91)29-27-45)62(98)81-40-55(92)80-41-56(93)82-52(38-44-19-11-10-12-20-44)61(97)87-51(37-42(4)5)60(96)84-47(22-15-31-77-67(71)72)58(94)83-48(23-16-32-78-68(73)74)59(95)88-57(43(6)9-3)64(100)85-49(24-17-33-79-69(75)76)65(101)90-36-18-25-53(90)63(99)86-50(66(102)103)21-13-14-30-70/h7-8,10-12,19-20,26-29,42-43,47-54,57,91H,1-2,9,13-18,21-25,30-41,70H2,3-6H3,(H,80,92)(H,81,98)(H,82,93)(H,83,94)(H,84,96)(H,85,100)(H,86,99)(H,87,97)(H,88,95)(H,102,103)(H4,71,72,77)(H4,73,74,78)(H4,75,76,79)/t43-,47-,48-,49-,50-,51-,52-,53+,54-,57-/m0/s1 PUPCCTCXOWBBTI-NYFSRWEWSA-N 50002349 CHEMBL413160::[N,N-diallylTyr1, D-pro10]Dynorphin A(1-11) Mu-type opioid receptor Cavia cutleri 32 ChEMBL 10.1021/jm00102a019 10.7270/Q2416XPM 1361580 Choi, H; Murray, TF; DeLander, GE; Caldwell, V; Aldrich, JV Oregon State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002349&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25092437 103916655 CHEMBL413160 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50058068 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NCC1CC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C67H109N21O13/c1-5-40(4)55(62(98)84-47(20-13-31-77-67(73)74)63(99)88-32-14-21-52(88)61(97)85-48(64(100)101)17-9-10-28-68)87-58(94)46(19-12-30-76-66(71)72)82-57(93)45(18-11-29-75-65(69)70)83-59(95)50(33-39(2)3)86-60(96)51(35-41-15-7-6-8-16-41)81-54(91)38-79-53(90)37-80-56(92)49(78-36-43-22-23-43)34-42-24-26-44(89)27-25-42/h6-8,15-16,24-27,39-40,43,45-52,55,78,89H,5,9-14,17-23,28-38,68H2,1-4H3,(H,79,90)(H,80,92)(H,81,91)(H,82,93)(H,83,95)(H,84,98)(H,85,97)(H,86,96)(H,87,94)(H,100,101)(H4,69,70,75)(H4,71,72,76)(H4,73,74,77)/t40-,45-,46-,47-,48-,49-,50-,51-,52+,55-/m0/s1 CFPWTFGNSPUUJD-GZFUILBVSA-N 50002347 CHEMBL425806::[N-cyclopropyl methylTyr1, D-pro10]Dynorphin A(1-11) Mu-type opioid receptor Cavia cutleri 9.6 ChEMBL 10.1021/jm00102a019 10.7270/Q2416XPM 1361580 Choi, H; Murray, TF; DeLander, GE; Caldwell, V; Aldrich, JV Oregon State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002347&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44361311 103916653 CHEMBL425806 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50058072 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NCC=C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C66H107N21O13/c1-6-29-74-48(35-42-24-26-43(88)27-25-42)55(91)79-37-52(89)78-38-53(90)80-50(36-41-17-9-8-10-18-41)59(95)85-49(34-39(3)4)58(94)82-44(20-13-30-75-64(68)69)56(92)81-45(21-14-31-76-65(70)71)57(93)86-54(40(5)7-2)61(97)83-46(22-15-32-77-66(72)73)62(98)87-33-16-23-51(87)60(96)84-47(63(99)100)19-11-12-28-67/h6,8-10,17-18,24-27,39-40,44-51,54,74,88H,1,7,11-16,19-23,28-38,67H2,2-5H3,(H,78,89)(H,79,91)(H,80,90)(H,81,92)(H,82,94)(H,83,97)(H,84,96)(H,85,95)(H,86,93)(H,99,100)(H4,68,69,75)(H4,70,71,76)(H4,72,73,77)/t40-,44-,45-,46-,47-,48-,49-,50-,51+,54-/m0/s1 MKKPRLAUMQVIGT-BMLSPESSSA-N 50002350 CHEMBL265387::[N-allylTyr1, D-pro10]Dynorphin A(1-11) Mu-type opioid receptor Cavia cutleri 11 ChEMBL 10.1021/jm00102a019 10.7270/Q2416XPM 1361580 Choi, H; Murray, TF; DeLander, GE; Caldwell, V; Aldrich, JV Oregon State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002350&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44361306 103916656 CHEMBL265387 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50058074 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C63H103N21O13/c1-5-37(4)51(58(94)80-44(20-13-29-74-63(70)71)59(95)84-30-14-21-48(84)57(93)81-45(60(96)97)17-9-10-26-64)83-54(90)43(19-12-28-73-62(68)69)78-53(89)42(18-11-27-72-61(66)67)79-55(91)46(31-36(2)3)82-56(92)47(33-38-15-7-6-8-16-38)77-50(87)35-75-49(86)34-76-52(88)41(65)32-39-22-24-40(85)25-23-39/h6-8,15-16,22-25,36-37,41-48,51,85H,5,9-14,17-21,26-35,64-65H2,1-4H3,(H,75,86)(H,76,88)(H,77,87)(H,78,89)(H,79,91)(H,80,94)(H,81,93)(H,82,92)(H,83,90)(H,96,97)(H4,66,67,72)(H4,68,69,73)(H4,70,71,74)/t37-,41-,42-,43-,44-,45-,46-,47-,48+,51-/m0/s1 WZHQALIQGVYQGG-DTQUPHKSSA-N 50002346 CHEMBL384584::[D-pro10]Dynorphin A(1-11) Mu-type opioid receptor Cavia cutleri 0.240000 ChEMBL 10.1021/jm00102a019 10.7270/Q2416XPM 1361580 Choi, H; Murray, TF; DeLander, GE; Caldwell, V; Aldrich, JV Oregon State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002346&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10351514 103916652 CHEMBL384584 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50058075 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NCc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C70H109N21O13/c1-5-43(4)58(65(101)87-50(25-16-34-80-70(76)77)66(102)91-35-17-26-55(91)64(100)88-51(67(103)104)22-12-13-31-71)90-61(97)49(24-15-33-79-69(74)75)85-60(96)48(23-14-32-78-68(72)73)86-62(98)53(36-42(2)3)89-63(99)54(38-44-18-8-6-9-19-44)84-57(94)41-82-56(93)40-83-59(95)52(37-45-27-29-47(92)30-28-45)81-39-46-20-10-7-11-21-46/h6-11,18-21,27-30,42-43,48-55,58,81,92H,5,12-17,22-26,31-41,71H2,1-4H3,(H,82,93)(H,83,95)(H,84,94)(H,85,96)(H,86,98)(H,87,101)(H,88,100)(H,89,99)(H,90,97)(H,103,104)(H4,72,73,78)(H4,74,75,79)(H4,76,77,80)/t43-,48-,49-,50-,51-,52-,53-,54-,55+,58-/m0/s1 SCUDNMPTYPZVCN-NRCLYKANSA-N 50002345 CHEMBL407529::PhCH2Tyr-Gly-Gly-Phe-Leu-Arg-Arg-lle-Arg-D-Pro10-LysOH::[N-benzylTyr1, D-pro10]Dynorphin A(1-11) Mu-type opioid receptor Cavia cutleri 31 ChEMBL 10.1021/jm00102a019 10.7270/Q2416XPM 1361580 Choi, H; Murray, TF; DeLander, GE; Caldwell, V; Aldrich, JV Oregon State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002345 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002345&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44361303 103916651 CHEMBL407529 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50058081 CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C19H26Cl2N2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17-,18-/m1/s1 VQLPLYSROCPWFF-QZTJIDSGSA-N 50000296 CHEMBL441765::CHEMBL482811::U-50488H::US11492374, ID 1 Mu-type opioid receptor Cavia cutleri 206 ChEMBL 10.1021/jm00102a019 10.7270/Q2416XPM 1361580 Choi, H; Murray, TF; DeLander, GE; Caldwell, V; Aldrich, JV Oregon State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000296&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036289 103914903 73358 CHEMBL482811CHEMBL441765 1654 C11796 ZINC00643032 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50060388 Cn1c2C[C@H]3CCN(C[C@@H]3Cc2c2C[C@@]3(O)C4Cc5ccc(O)c6O[C@@H](c12)[C@]3(CCN4CC1CC1)c56)C(=O)OCc1ccccc1 InChI=1S/C38H43N3O5/c1-39-29-16-24-11-13-41(36(43)45-21-23-5-3-2-4-6-23)20-26(24)15-27(29)28-18-38(44)31-17-25-9-10-30(42)34-32(25)37(38,35(46-34)33(28)39)12-14-40(31)19-22-7-8-22/h2-6,9-10,22,24,26,31,35,42,44H,7-8,11-21H2,1H3/t24-,26+,31?,35+,37+,38-/m1/s1 BCPUGGCDIQTIQA-SEVBBMNCSA-N 50044863 17-(Cyclopropylmethyl)-6,7-didehydro-3,14-dihydroxy-4,5beta-epoxy-6,7:2',3'-[[N-(benzyloxycarbonyl)piperidino][3,4-f](N-methyl-4',5'(R),6'(R),7'-tetrahydroindolo)]morphinan Mu-type opioid receptor Cavia cutleri 1.7 ChEMBL 10.1021/jm00068a020 10.7270/Q2MP53WW 8360887 Lin, CE; Takemori, AE; Portoghese, PS University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044863&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44317553 103975976 ZINC26482829 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50060389 Cn1c2C[C@H]3CCNC[C@@H]3Cc2c2C[C@@]3(O)C4Cc5ccc(O)c6O[C@@H](c12)[C@]3(CCN4CC1CC1)c56 InChI=1S/C30H37N3O3/c1-32-22-11-17-6-8-31-14-19(17)10-20(22)21-13-30(35)24-12-18-4-5-23(34)27-25(18)29(30,28(36-27)26(21)32)7-9-33(24)15-16-2-3-16/h4-5,16-17,19,24,28,31,34-35H,2-3,6-15H2,1H3/t17-,19+,24?,28+,29+,30-/m1/s1 SZENRBNMGXKTPI-NCODPRDNSA-N 50044865 17-(Cyclopropylmethyl)-6,7-didehydro-3,14-dihydroxy-4,5beta-epoxy-6,7:2',3'-[piperidino[3,4-f](N-methyl-4',5'(R),6'(R),7'-tetrahydroindolo)]morphinan Mu-type opioid receptor Cavia cutleri 1 ChEMBL 10.1021/jm00068a020 10.7270/Q2MP53WW 8360887 Lin, CE; Takemori, AE; Portoghese, PS University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044865&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44317512 103975977 ZINC26477675 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50060393 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2[C@@H]4Oc6c7c(C[C@H]8N(CC9CC9)CC[C@@]47[C@@]8(O)Cc2c1C[C@@]35O)ccc6O InChI=1S/C40H43N3O6/c44-25-7-5-21-13-27-39(46)15-23-24-16-40(47)28-14-22-6-8-26(45)34-30(22)38(40,10-12-43(28)18-20-3-4-20)36(49-34)32(24)41-31(23)35-37(39,29(21)33(25)48-35)9-11-42(27)17-19-1-2-19/h5-8,19-20,27-28,35-36,41,44-47H,1-4,9-18H2/t27-,28-,35+,36+,37+,38+,39-,40-/m1/s1 APSUXPSYBJVPPS-YAUKWVCOSA-N 82551 C18130::CAS_105618-26-6::NOR-BNI (HCI)2::NORBNI Mu-type opioid receptor Cavia cutleri 8.3 ChEMBL 10.1021/jm00068a020 10.7270/Q2MP53WW 8360887 Lin, CE; Takemori, AE; Portoghese, PS University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82551&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5480230 136350521 C18130 ZINC03995590 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50059461 CCCCC(=N)NCc1ccc2[nH]c3C4Oc5c6c(CC7N(CC8CC8)CC[C@@]46[C@@]7(O)Cc3c2c1)ccc5O InChI=1S/C32H38N4O3/c1-2-3-4-26(33)34-16-19-7-9-23-21(13-19)22-15-32(38)25-14-20-8-10-24(37)29-27(20)31(32,30(39-29)28(22)35-23)11-12-36(25)17-18-5-6-18/h7-10,13,18,25,30,35,37-38H,2-6,11-12,14-17H2,1H3,(H2,33,34)/t25?,30?,31-,32+/m0/s1 LHABVQRHEYQPMS-CSNANGCCSA-N 50044871 22-cyclopropylmethyl-7-(1-iminopentylaminomethyl)-(2S)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaene-2,16-diol Mu-type opioid receptor Cavia cutleri 3.5 ChEMBL 10.1021/jm00053a025 10.7270/Q2Z60PPM 8380614 Olmsted, SL; Takemori, AE; Portoghese, PS University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044871&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44295758 103975983 ZINC36221082 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50059462 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2[C@@H]4Oc6c7c(C[C@H]8N(CC9CC9)CC[C@@]47[C@@]8(O)Cc2c1C[C@@]35O)ccc6O InChI=1S/C40H43N3O6/c44-25-7-5-21-13-27-39(46)15-23-24-16-40(47)28-14-22-6-8-26(45)34-30(22)38(40,10-12-43(28)18-20-3-4-20)36(49-34)32(24)41-31(23)35-37(39,29(21)33(25)48-35)9-11-42(27)17-19-1-2-19/h5-8,19-20,27-28,35-36,41,44-47H,1-4,9-18H2/t27-,28-,35+,36+,37+,38+,39-,40-/m1/s1 APSUXPSYBJVPPS-YAUKWVCOSA-N 82551 C18130::CAS_105618-26-6::NOR-BNI (HCI)2::NORBNI Mu-type opioid receptor Cavia cutleri 47 ChEMBL 10.1021/jm00053a025 10.7270/Q2Z60PPM 8380614 Olmsted, SL; Takemori, AE; Portoghese, PS University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82551&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5480230 136350521 C18130 ZINC03995590 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50060580 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)CC1(Cc2ccccc2C1)C4=O)ccc5O InChI=1S/C25H25NO4/c1-26-9-8-24-19-14-6-7-17(27)20(19)30-22(24)21(28)23(13-25(24,29)18(26)10-14)11-15-4-2-3-5-16(15)12-23/h2-7,18,22,27,29H,8-13H2,1H3/t18-,22+,24+,25-/m1/s1 YJWDKWRVFJZBCJ-QVJDATKISA-N 50297170 7-(2'-spiroindanyl)oxymorphone::7-(Spiroindano)Oxymorphone::7-spiroindanyloxymorphone::CHEMBL399708::SIOM::Spiroindanyloxymorphone Mu-type opioid receptor Cavia cutleri 11 ChEMBL 10.1021/jm00069a017 10.7270/Q27H1K62 8394935 Portoghese, PS; Moe, ST; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297170 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297170&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44444966 104138701 CHEMBL399708 ZINC13555461 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50061796 COC(=O)\C=C\C(=O)N[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45 InChI=1S/C25H30N2O6/c1-32-20(30)7-6-19(29)26-16-8-9-25(31)18-12-15-4-5-17(28)22-21(15)24(25,23(16)33-22)10-11-27(18)13-14-2-3-14/h4-7,14,16,18,23,28,31H,2-3,8-13H2,1H3,(H,26,29)/b7-6+/t16-,18-,23+,24+,25-/m1/s1 PQKHESYTSKMWFP-WZJCLRDWSA-N 50247803 Beta-Funeltrexamine::CHEMBL473136::beta-funaltrexamine::methyl (2E)-3-{[(1S,5R,13R,14R,17S)-4-(cyclopropylmethyl)-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10-trien-14-yl]carbamoyl}prop-2-enoate::methyl 3-[4-cyclopropylmethyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-ylcarbamoyl]-(E)-2-propenoate Mu-type opioid receptor Cavia cutleri 4.8 ChEMBL 10.1021/jm00075a023 10.7270/Q2W096JR 8246236 Larson, DL; Hua, M; Takemori, AE; Portoghese, PS University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50247803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50247803&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311018 104102600 CHEMBL473136 1631 C18127 ZINC03995756 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50061797 COC(=O)CC(SCC(NC(=O)CCC(N)C(O)=O)C(=O)NCC(O)=O)C(=O)N[C@@H]1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45 InChI=1S/C35H47N5O12S/c1-51-27(45)13-23(53-16-21(31(46)37-14-26(43)44)38-25(42)7-5-19(36)33(48)49)32(47)39-20-8-9-35(50)24-12-18-4-6-22(41)29-28(18)34(35,30(20)52-29)10-11-40(24)15-17-2-3-17/h4,6,17,19-21,23-24,30,41,50H,2-3,5,7-16,36H2,1H3,(H,37,46)(H,38,42)(H,39,47)(H,43,44)(H,48,49)/t19?,20-,21?,23?,24?,30+,34+,35-/m1/s1 CMXFDERRQSFBJM-HIHBSZIXSA-N 50042662 2-amino-4-(1-carboxymethylcarbamoyl-2-{1-[4-cyclopropylmethyl-10,17-dihydroxy-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-ylcarbamoyl]-2-methyloxycarbonylethylsulfanyl}ethylcarbamoyl)butanoic acid::CID44347299::beta-NFA conjugate 3 Mu-type opioid receptor Cavia cutleri 41 ChEMBL 10.1021/jm00075a023 10.7270/Q2W096JR 8246236 Larson, DL; Hua, M; Takemori, AE; Portoghese, PS University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042662 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042662&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44347299 103974248 ZINC96209946 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50061798 COC(=O)CC(SCC(N)C(O)=O)C(=O)N[C@@H]1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45 InChI=1S/C28H37N3O8S/c1-38-21(33)11-19(40-13-16(29)26(35)36)25(34)30-17-6-7-28(37)20-10-15-4-5-18(32)23-22(15)27(28,24(17)39-23)8-9-31(20)12-14-2-3-14/h4-5,14,16-17,19-20,24,32,37H,2-3,6-13,29H2,1H3,(H,30,34)(H,35,36)/t16?,17-,19?,20?,24+,27+,28-/m1/s1 PPTZLRVVMLVSKV-NEBMTGGDSA-N 50042660 2-amino-3-{1-[4-cyclopropylmethyl-10,17-dihydroxy-(13R,14R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-ylcarbamoyl]-2-methyloxycarbonylethylsulfanyl}propanoic acid::CID44347067::beta-NFA conjugate 4 Mu-type opioid receptor Cavia cutleri 22 ChEMBL 10.1021/jm00075a023 10.7270/Q2W096JR 8246236 Larson, DL; Hua, M; Takemori, AE; Portoghese, PS University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042660 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042660&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44347067 103974246 ZINC36221972 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50065080 NC(=O)c1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CCC3)c2c1 InChI=1S/C22H28N2O2/c23-21(26)15-7-8-16-18(12-15)22-9-2-1-6-17(22)19(20(16)25)24(11-10-22)13-14-4-3-5-14/h7-8,12,14,17,19H,1-6,9-11,13H2,(H2,23,26)/t17-,19-,22+/m0/s1 YKFDGWCTDGRKMH-LQBOVUBWSA-N 50138013 3-Carboxamido-10-keto-N-cyclobutylmethylmorphinan::CHEMBL296282 Mu-type opioid receptor Cavia cutleri 2.5 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50138013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50138013&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11405480 104028151 CHEMBL296282 ZINC13532307 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50065085 COCCN1CC[C@]23CCCC[C@H]2[C@H]1C(=O)c1ccc(O)cc31 InChI=1S/C19H25NO3/c1-23-11-10-20-9-8-19-7-3-2-4-15(19)17(20)18(22)14-6-5-13(21)12-16(14)19/h5-6,12,15,17,21H,2-4,7-11H2,1H3/t15-,17-,19+/m0/s1 RPXGXTZSTJDASM-VDZJLULYSA-N 50137992 3-Hydroxy-10-keto-N-(2-methoxyethyl)morphinan::CHEMBL432873 Mu-type opioid receptor Cavia cutleri 90 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137992&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11392900 104028130 CHEMBL432873 ZINC13532285 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50065090 Oc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3Cc3ccc4ccccc4c3)c2c1 InChI=1S/C27H27NO2/c29-21-10-11-22-24(16-21)27-12-4-3-7-23(27)25(26(22)30)28(14-13-27)17-18-8-9-19-5-1-2-6-20(19)15-18/h1-2,5-6,8-11,15-16,23,25,29H,3-4,7,12-14,17H2/t23-,25-,27+/m0/s1 KYQHQUFUGAUIJV-SCTDOJESSA-N 50138009 3-Hydroxy-10-keto-N-(2-naphthylmethyl)morphinan::CHEMBL47488 Mu-type opioid receptor Cavia cutleri 2200 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50138009 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50138009&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 12112720 104028147 CHEMBL47488 ZINC13532291 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50065093 Oc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3CCc3ccccc3)c2c1 InChI=1S/C24H27NO2/c26-18-9-10-19-21(16-18)24-12-5-4-8-20(24)22(23(19)27)25(15-13-24)14-11-17-6-2-1-3-7-17/h1-3,6-7,9-10,16,20,22,26H,4-5,8,11-15H2/t20-,22-,24+/m0/s1 UWKQEYUXARXPSA-ODGPQVTHSA-N 50138011 3-Hydroxy-10-keto-N-(2-phenylethyl)morphinan::CHEMBL48390 Mu-type opioid receptor Cavia cutleri 0.63 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50138011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50138011&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11394342 104028149 CHEMBL48390 ZINC13532288 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50065108 CN1CC[C@]23CCCC[C@H]2[C@H]1Cc1ccc(CN)cc31 InChI=1S/C18H26N2/c1-20-9-8-18-7-3-2-4-15(18)17(20)11-14-6-5-13(12-19)10-16(14)18/h5-6,10,15,17H,2-4,7-9,11-12,19H2,1H3/t15-,17+,18+/m0/s1 XYIFHCHUVGLMRO-CGTJXYLNSA-N 50138000 3-Aminomethyl-N-methylmorphinan::CHEMBL49318 Mu-type opioid receptor Cavia cutleri 66 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50138000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50138000&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11402990 104028138 CHEMBL49318 ZINC13532335 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50065118 NC(=O)c1ccc2C[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CCC3)c2c1 InChI=1S/C22H30N2O/c23-21(25)17-8-7-16-13-20-18-6-1-2-9-22(18,19(16)12-17)10-11-24(20)14-15-4-3-5-15/h7-8,12,15,18,20H,1-6,9-11,13-14H2,(H2,23,25)/t18-,20+,22+/m0/s1 GIZYPGRXWUVSHP-CZTZKLFOSA-N 50137994 3-Carboxamido-N-cyclobutylmethylmorphinan::CHEMBL433272 Mu-type opioid receptor Cavia cutleri 0.10 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137994&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11279188 104028132 CHEMBL433272 ZINC13532347 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50065119 Oc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CCC3)c2c1 InChI=1S/C21H27NO2/c23-15-7-8-16-18(12-15)21-9-2-1-6-17(21)19(20(16)24)22(11-10-21)13-14-4-3-5-14/h7-8,12,14,17,19,23H,1-6,9-11,13H2/t17-,19-,21+/m0/s1 OOATVKPPMTVMQN-HFSMHLIXSA-N 50137990 3-Hydroxy-10-keto-N-cyclobutylmethylmorphinan::CHEMBL48241 Mu-type opioid receptor Cavia cutleri 3.3 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137990 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137990&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11771732 104028128 CHEMBL48241 ZINC13532272 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50065120 Oc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3C[C@@H]3CCCO3)c2c1 InChI=1S/C21H27NO3/c23-14-6-7-16-18(12-14)21-8-2-1-5-17(21)19(20(16)24)22(10-9-21)13-15-4-3-11-25-15/h6-7,12,15,17,19,23H,1-5,8-11,13H2/t15-,17-,19-,21+/m0/s1 BSCRKXLANCGZGY-WRGRXTPVSA-N 50137989 3-Hydroxy-10-keto-N-(tetrahydrofuran-2-yl)methylmorphinan::CHEMBL301804 Mu-type opioid receptor Cavia cutleri 0.38 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137989 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137989&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10664954 104028127 CHEMBL301804 ZINC13803761 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50065121 Nc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CCC3)c2c1 InChI=1S/C21H28N2O/c22-15-7-8-16-18(12-15)21-9-2-1-6-17(21)19(20(16)24)23(11-10-21)13-14-4-3-5-14/h7-8,12,14,17,19H,1-6,9-11,13,22H2/t17-,19-,21+/m0/s1 RWOONUDEZVLRNB-HFSMHLIXSA-N 50138008 3-Amino-10-keto-N-cyclobutylmethylmorphinan::CHEMBL300877 Mu-type opioid receptor Cavia cutleri 23 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50138008 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50138008&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11209549 104028146 CHEMBL300877 ZINC13532301 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50065122 CN1CC[C@]23CCCC[C@H]2[C@H]1Cc1ccc(cc31)C#N InChI=1S/C18H22N2/c1-20-9-8-18-7-3-2-4-15(18)17(20)11-14-6-5-13(12-19)10-16(14)18/h5-6,10,15,17H,2-4,7-9,11H2,1H3/t15-,17+,18+/m0/s1 AGLRKZPEAXCOCK-CGTJXYLNSA-N 50137999 3-Cyano-N-methylmorphinan::CHEMBL296304 Mu-type opioid receptor Cavia cutleri 20 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137999 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137999&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44293140 104028137 CHEMBL296304 ZINC13532313 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50065123 O=C(Nc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CCC3)c2c1)c1ccccc1 InChI=1S/C28H32N2O2/c31-26-22-13-12-21(29-27(32)20-9-2-1-3-10-20)17-24(22)28-14-5-4-11-23(28)25(26)30(16-15-28)18-19-7-6-8-19/h1-3,9-10,12-13,17,19,23,25H,4-8,11,14-16,18H2,(H,29,32)/t23-,25-,28+/m0/s1 HMZOMKWKBKHNRX-YRLRHBCXSA-N 50137998 3-Benzylamino-10-keto-N-cyclobutylmethylmorphinan::CHEMBL49106 Mu-type opioid receptor Cavia cutleri 4.4 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137998 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137998&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11327829 104028136 CHEMBL49106 ZINC29464746 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50065125 CN1CC[C@]23CCCC[C@H]2[C@H]1Cc1ccc(N)cc31 InChI=1S/C17H24N2/c1-19-9-8-17-7-3-2-4-14(17)16(19)10-12-5-6-13(18)11-15(12)17/h5-6,11,14,16H,2-4,7-10,18H2,1H3/t14-,16+,17+/m0/s1 CYPHSPITDGFDMD-USXIJHARSA-N 50138010 3-Amino-N-methylmorphinan::CHEMBL48420::US10766864, Example 114 Mu-type opioid receptor Cavia cutleri 7.9 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50138010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50138010&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15934554 104028148 CHEMBL48420 ZINC13532319 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50065128 N#Cc1ccc2C[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CCC3)c2c1 InChI=1S/C22H28N2/c23-14-17-7-8-18-13-21-19-6-1-2-9-22(19,20(18)12-17)10-11-24(21)15-16-4-3-5-16/h7-8,12,16,19,21H,1-6,9-11,13,15H2/t19-,21+,22+/m0/s1 SRPOCVPRBWPZFP-KSEOMHKRSA-N 50138001 3-Cyano-N-cyclobutylmethylmorphinan::CHEMBL48157 Mu-type opioid receptor Cavia cutleri 37 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50138001 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50138001&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11209418 104028139 CHEMBL48157 ZINC13532316 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50065131 Oc1ccc2C(=O)[C@H]3NCC[C@@]4(CCCC[C@@H]34)c2c1 InChI=1S/C16H19NO2/c18-10-4-5-11-13(9-10)16-6-2-1-3-12(16)14(15(11)19)17-8-7-16/h4-5,9,12,14,17-18H,1-3,6-8H2/t12-,14-,16+/m0/s1 QPSFDJPYIFLKBV-DUVNUKRYSA-N 50138006 3-hydroxy-normorphinan::CHEMBL48936 Mu-type opioid receptor Cavia cutleri 20 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50138006 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50138006&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10706296 104028144 CHEMBL48936 ZINC13532250 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50064580 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCCCCCCNC(=O)[C@H](N)Cc1c(C)cc(O)cc1C InChI=1S/C30H46N4O4/c1-19-13-23(35)14-20(2)25(19)17-27(31)29(37)33-11-9-7-5-6-8-10-12-34-30(38)28(32)18-26-21(3)15-24(36)16-22(26)4/h13-16,27-28,35-36H,5-12,17-18,31-32H2,1-4H3,(H,33,37)(H,34,38)/t27-,28+ VNIKIAIFGZCFAJ-HNRBIFIRSA-N 50130619 2-Amino-N-{8-[2-amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionylamino]-octyl}-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionamide::CHEMBL323216 Mu-type opioid receptor Cavia cutleri 54 ChEMBL 10.1021/jm020459z 10.7270/Q28C9VMQ 12852751 Okada, Y; Tsuda, Y; Fujita, Y; Yokoi, T; Sasaki, Y; Ambo, A; Konishi, R; Nagata, M; Salvadori, S; Jinsmaa, Y; Bryant, SD; Lazarus, LH Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130619 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130619&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44338485 104021931 CHEMBL323216 ZINC26947086 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50064581 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCCCCNC(=O)[C@H](N)Cc1c(C)cc(O)cc1C InChI=1S/C28H42N4O4/c1-17-11-21(33)12-18(2)23(17)15-25(29)27(35)31-9-7-5-6-8-10-32-28(36)26(30)16-24-19(3)13-22(34)14-20(24)4/h11-14,25-26,33-34H,5-10,15-16,29-30H2,1-4H3,(H,31,35)(H,32,36)/t25-,26+ RRGJXNYBDGUXGY-WMPKNSHKSA-N 50130617 2-Amino-N-{6-[2-amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionylamino]-hexyl}-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionamide::CHEMBL108808 Mu-type opioid receptor Cavia cutleri 3.1 ChEMBL 10.1021/jm020459z 10.7270/Q28C9VMQ 12852751 Okada, Y; Tsuda, Y; Fujita, Y; Yokoi, T; Sasaki, Y; Ambo, A; Konishi, R; Nagata, M; Salvadori, S; Jinsmaa, Y; Bryant, SD; Lazarus, LH Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130617&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44338484 104021929 CHEMBL108808 ZINC26947077 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50064582 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCNC(=O)[C@H](N)Cc1c(C)cc(O)cc1C InChI=1S/C24H34N4O4/c1-13-7-17(29)8-14(2)19(13)11-21(25)23(31)27-5-6-28-24(32)22(26)12-20-15(3)9-18(30)10-16(20)4/h7-10,21-22,29-30H,5-6,11-12,25-26H2,1-4H3,(H,27,31)(H,28,32)/t21-,22+ KLNHGSFLGAYBKI-SZPZYZBQSA-N 50130614 2-Amino-N-{2-[2-amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionylamino]-ethyl}-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionamide::CHEMBL109204 Mu-type opioid receptor Cavia cutleri 2844 ChEMBL 10.1021/jm020459z 10.7270/Q28C9VMQ 12852751 Okada, Y; Tsuda, Y; Fujita, Y; Yokoi, T; Sasaki, Y; Ambo, A; Konishi, R; Nagata, M; Salvadori, S; Jinsmaa, Y; Bryant, SD; Lazarus, LH Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130614 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130614&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44338441 104021926 CHEMBL109204 ZINC26947123 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50064583 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCCNC(=O)[C@H](N)Cc1ccc(O)cc1 InChI=1S/C24H34N4O4/c1-15-11-19(30)12-16(2)20(15)14-22(26)24(32)28-10-4-3-9-27-23(31)21(25)13-17-5-7-18(29)8-6-17/h5-8,11-12,21-22,29-30H,3-4,9-10,13-14,25-26H2,1-2H3,(H,27,31)(H,28,32)/t21-,22+/m1/s1 GHFRSFJFEXFNGH-YADHBBJMSA-N 50130613 2-Amino-N-{4-[2-amino-3-(4-hydroxy-phenyl)-propionylamino]-butyl}-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionamide::CHEMBL109818 Mu-type opioid receptor Cavia cutleri 255 ChEMBL 10.1021/jm020459z 10.7270/Q28C9VMQ 12852751 Okada, Y; Tsuda, Y; Fujita, Y; Yokoi, T; Sasaki, Y; Ambo, A; Konishi, R; Nagata, M; Salvadori, S; Jinsmaa, Y; Bryant, SD; Lazarus, LH Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130613 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130613&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44338460 104021925 CHEMBL109818 ZINC26970876 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50064584 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCCNC(=O)[C@H](N)Cc1c(C)cc(O)cc1C InChI=1S/C26H38N4O4/c1-15-9-19(31)10-16(2)21(15)13-23(27)25(33)29-7-5-6-8-30-26(34)24(28)14-22-17(3)11-20(32)12-18(22)4/h9-12,23-24,31-32H,5-8,13-14,27-28H2,1-4H3,(H,29,33)(H,30,34)/t23-,24+ XNDDFGCHFYFKSW-PSWAGMNNSA-N 50130611 2-Amino-N-{4-[2-amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionylamino]-butyl}-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionamide::CHEMBL108640 Mu-type opioid receptor Cavia cutleri 5.3 ChEMBL 10.1021/jm020459z 10.7270/Q28C9VMQ 12852751 Okada, Y; Tsuda, Y; Fujita, Y; Yokoi, T; Sasaki, Y; Ambo, A; Konishi, R; Nagata, M; Salvadori, S; Jinsmaa, Y; Bryant, SD; Lazarus, LH Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130611 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130611&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44338523 104021923 CHEMBL108640 ZINC26951771 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50064585 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCCNC(=O)[C@H](N)Cc1ccccc1 InChI=1S/C24H34N4O3/c1-16-12-19(29)13-17(2)20(16)15-22(26)24(31)28-11-7-6-10-27-23(30)21(25)14-18-8-4-3-5-9-18/h3-5,8-9,12-13,21-22,29H,6-7,10-11,14-15,25-26H2,1-2H3,(H,27,30)(H,28,31)/t21-,22+/m1/s1 HMTQHYZKAYZSKP-YADHBBJMSA-N 50130612 2-Amino-N-[4-(2-amino-3-phenyl-propionylamino)-butyl]-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionamide::CHEMBL109203 Mu-type opioid receptor Cavia cutleri 181 ChEMBL 10.1021/jm020459z 10.7270/Q28C9VMQ 12852751 Okada, Y; Tsuda, Y; Fujita, Y; Yokoi, T; Sasaki, Y; Ambo, A; Konishi, R; Nagata, M; Salvadori, S; Jinsmaa, Y; Bryant, SD; Lazarus, LH Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130612 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130612&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44338432 104021924 CHEMBL109203 ZINC26946786 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062588 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(N)=O InChI=1S/C28H35N5O5/c29-21(16-19-10-12-20(34)13-11-19)27(37)33-15-5-9-24(33)26(36)31-22(17-18-6-2-1-3-7-18)28(38)32-14-4-8-23(32)25(30)35/h1-3,6-7,10-13,21-24,34H,4-5,8-9,14-17,29H2,(H2,30,35)(H,31,36)/t21-,22+,23-,24-/m0/s1 LSQXZIUREIDSHZ-KIHHCIJBSA-N 50456335 CHEMBL2371359 Mu-type opioid receptor Cavia cutleri 109 ChEMBL 10.1021/jm00058a007 10.7270/Q2Z03761 8384662 Yamazaki, T; Ro, S; Goodman, M; Chung, NN; Schiller, PW University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50456335 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50456335&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10391975 225147251 CHEMBL2371359 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062589 CN([C@@H](Cc1ccccc1)C(=O)N1CCC[C@@H]1C(N)=O)C(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C29H37N5O5/c1-32(25(18-19-7-3-2-4-8-19)29(39)33-15-5-9-23(33)26(31)36)28(38)24-10-6-16-34(24)27(37)22(30)17-20-11-13-21(35)14-12-20/h2-4,7-8,11-14,22-25,35H,5-6,9-10,15-18,30H2,1H3,(H2,31,36)/t22-,23+,24-,25-/m0/s1 JAKBYSTWCHUQOK-NDBXHCKUSA-N 50140906 1-[2-[1-[2-amino-3-(4-hydroxyphenyl)-(2S)-propanoyl]-(5S)-dihydro-1H-5-pyrrolyl(methyl)carboxamido]-3-phenyl-(2S)-propanoyl]-(5R)-dihydro-1H-5-pyrrolecarboxamide::CHEMBL283287 Mu-type opioid receptor Cavia cutleri 21 ChEMBL 10.1021/jm00058a007 10.7270/Q2Z03761 8384662 Yamazaki, T; Ro, S; Goodman, M; Chung, NN; Schiller, PW University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140906 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140906&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 115335 104030442 CHEMBL283287 1671 ZINC14953444 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062590 C[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@@H]1C(N)=O InChI=1S/C26H33N5O5/c1-16(29-25(35)20(27)14-18-9-11-19(32)12-10-18)24(34)30-21(15-17-6-3-2-4-7-17)26(36)31-13-5-8-22(31)23(28)33/h2-4,6-7,9-12,16,20-22,32H,5,8,13-15,27H2,1H3,(H2,28,33)(H,29,35)(H,30,34)/t16-,20-,21-,22+/m0/s1 FXLMJAFFLZEZHN-IRNNPGBSSA-N 50456333 CHEMBL2371361 Mu-type opioid receptor Cavia cutleri 26900 ChEMBL 10.1021/jm00058a007 10.7270/Q2Z03761 8384662 Yamazaki, T; Ro, S; Goodman, M; Chung, NN; Schiller, PW University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50456333 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50456333&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9983255 225147249 CHEMBL2371361 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062591 C[C@H](N(C)C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@@H]1C(N)=O InChI=1S/C27H35N5O5/c1-17(31(2)26(36)21(28)15-19-10-12-20(33)13-11-19)25(35)30-22(16-18-7-4-3-5-8-18)27(37)32-14-6-9-23(32)24(29)34/h3-5,7-8,10-13,17,21-23,33H,6,9,14-16,28H2,1-2H3,(H2,29,34)(H,30,35)/t17-,21-,22-,23+/m0/s1 PAVMQNDNZSJTHU-KEIZBESESA-N 50456336 CHEMBL2371360 Mu-type opioid receptor Cavia cutleri 31 ChEMBL 10.1021/jm00058a007 10.7270/Q2Z03761 8384662 Yamazaki, T; Ro, S; Goodman, M; Chung, NN; Schiller, PW University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50456336 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50456336&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10097817 225147252 CHEMBL2371360 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062592 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(N)=O InChI=1S/C28H35N5O5/c29-21(16-19-10-12-20(34)13-11-19)27(37)33-15-5-9-24(33)26(36)31-22(17-18-6-2-1-3-7-18)28(38)32-14-4-8-23(32)25(30)35/h1-3,6-7,10-13,21-24,34H,4-5,8-9,14-17,29H2,(H2,30,35)(H,31,36)/t21-,22-,23-,24-/m0/s1 LSQXZIUREIDSHZ-ZJZGAYNASA-N 50166066 CHEMBL362991::H-Tyr-Pro-Phe-Pro-NH2::MORPHICEPTIN::Tyr-Pro-Phe-Pro-NH2::[D-Pro4]morphiceptin Mu-type opioid receptor Cavia cutleri 552 ChEMBL 10.1021/jm00058a007 10.7270/Q2Z03761 8384662 Yamazaki, T; Ro, S; Goodman, M; Chung, NN; Schiller, PW University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50166066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50166066&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 119303 104051482 CHEMBL362991 ZINC53057130 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062594 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@@H]1C(N)=O InChI=1S/C28H35N5O5/c29-21(16-19-10-12-20(34)13-11-19)27(37)33-15-5-9-24(33)26(36)31-22(17-18-6-2-1-3-7-18)28(38)32-14-4-8-23(32)25(30)35/h1-3,6-7,10-13,21-24,34H,4-5,8-9,14-17,29H2,(H2,30,35)(H,31,36)/t21-,22-,23+,24-/m0/s1 LSQXZIUREIDSHZ-XQUALCHDSA-N 50456337 CHEMBL267708 Mu-type opioid receptor Cavia cutleri 29 ChEMBL 10.1021/jm00058a007 10.7270/Q2Z03761 8384662 Yamazaki, T; Ro, S; Goodman, M; Chung, NN; Schiller, PW University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50456337 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50456337&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10075397 225147253 CHEMBL267708 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062596 CN([C@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(N)=O)C(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C29H37N5O5/c1-32(25(18-19-7-3-2-4-8-19)29(39)33-15-5-9-23(33)26(31)36)28(38)24-10-6-16-34(24)27(37)22(30)17-20-11-13-21(35)14-12-20/h2-4,7-8,11-14,22-25,35H,5-6,9-10,15-18,30H2,1H3,(H2,31,36)/t22-,23-,24-,25+/m0/s1 JAKBYSTWCHUQOK-OJJQZRKESA-N 50456338 CHEMBL2371337 Mu-type opioid receptor Cavia cutleri >100000 ChEMBL 10.1021/jm00058a007 10.7270/Q2Z03761 8384662 Yamazaki, T; Ro, S; Goodman, M; Chung, NN; Schiller, PW University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50456338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50456338&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10075831 225147254 CHEMBL2371337 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062597 CN([C@H](Cc1ccccc1)C(=O)N1CCC[C@@H]1C(N)=O)C(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C29H37N5O5/c1-32(25(18-19-7-3-2-4-8-19)29(39)33-15-5-9-23(33)26(31)36)28(38)24-10-6-16-34(24)27(37)22(30)17-20-11-13-21(35)14-12-20/h2-4,7-8,11-14,22-25,35H,5-6,9-10,15-18,30H2,1H3,(H2,31,36)/t22-,23+,24-,25+/m0/s1 JAKBYSTWCHUQOK-FQUZAXHOSA-N 50456339 CHEMBL2371336 Mu-type opioid receptor Cavia cutleri 2660 ChEMBL 10.1021/jm00058a007 10.7270/Q2Z03761 8384662 Yamazaki, T; Ro, S; Goodman, M; Chung, NN; Schiller, PW University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50456339 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50456339&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10437174 225147255 CHEMBL2371336 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062603 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](Cc1ccccc1)C(=O)N1CCC[C@@H]1C(N)=O InChI=1S/C28H35N5O5/c29-21(16-19-10-12-20(34)13-11-19)27(37)33-15-5-9-24(33)26(36)31-22(17-18-6-2-1-3-7-18)28(38)32-14-4-8-23(32)25(30)35/h1-3,6-7,10-13,21-24,34H,4-5,8-9,14-17,29H2,(H2,30,35)(H,31,36)/t21-,22+,23+,24-/m0/s1 LSQXZIUREIDSHZ-KEZOAJOQSA-N 50456334 CHEMBL2371340 Mu-type opioid receptor Cavia cutleri 557 ChEMBL 10.1021/jm00058a007 10.7270/Q2Z03761 8384662 Yamazaki, T; Ro, S; Goodman, M; Chung, NN; Schiller, PW University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50456334 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50456334&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10391976 225147250 CHEMBL2371340 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062604 CN([C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(N)=O)C(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C29H37N5O5/c1-32(25(18-19-7-3-2-4-8-19)29(39)33-15-5-9-23(33)26(31)36)28(38)24-10-6-16-34(24)27(37)22(30)17-20-11-13-21(35)14-12-20/h2-4,7-8,11-14,22-25,35H,5-6,9-10,15-18,30H2,1H3,(H2,31,36)/t22-,23-,24-,25-/m0/s1 JAKBYSTWCHUQOK-QORCZRPOSA-N 50456332 CHEMBL2371339 Mu-type opioid receptor Cavia cutleri 170 ChEMBL 10.1021/jm00058a007 10.7270/Q2Z03761 8384662 Yamazaki, T; Ro, S; Goodman, M; Chung, NN; Schiller, PW University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50456332 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50456332&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10437173 225147248 CHEMBL2371339 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062656 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C63H103N21O13/c1-5-37(4)51(58(94)80-44(20-13-29-74-63(70)71)59(95)84-30-14-21-48(84)57(93)81-45(60(96)97)17-9-10-26-64)83-54(90)43(19-12-28-73-62(68)69)78-53(89)42(18-11-27-72-61(66)67)79-55(91)46(31-36(2)3)82-56(92)47(33-38-15-7-6-8-16-38)77-50(87)35-75-49(86)34-76-52(88)41(65)32-39-22-24-40(85)25-23-39/h6-8,15-16,22-25,36-37,41-48,51,85H,5,9-14,17-21,26-35,64-65H2,1-4H3,(H,75,86)(H,76,88)(H,77,87)(H,78,89)(H,79,91)(H,80,94)(H,81,93)(H,82,92)(H,83,90)(H,96,97)(H4,66,67,72)(H4,68,69,73)(H4,70,71,74)/t37-,41-,42-,43-,44-,45-,46-,47-,48-,51-/m0/s1 WZHQALIQGVYQGG-QFIUEGLPSA-N 50040123 CHEMBL438223::HTry-Gly-Gly-Phe-Leu-Arg-Arg-lle-Arg-Pro-LysOH::Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys::[D-Pro-10]Dyn A-(1-11) Mu-type opioid receptor Cavia cutleri 3.8 ChEMBL 10.1021/jm00058a012 10.7270/Q2K936K7 8096246 Kawasaki, AM; Knapp, RJ; Kramer, TH; Walton, A; Wire, WS; Hashimoto, S; Yamamura, HI; Porreca, F; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040123 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040123&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3086114 103972184 CHEMBL438223 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062657 CC[C@H](C)[C@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SSC[C@@H](NC(=O)[C@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC1=O)C(O)=O InChI=1S/C59H92N20O13S2/c1-5-32(2)45-52(88)75-39(17-11-25-69-58(65)66)54(90)79-26-12-18-42(79)51(87)76-41(55(91)92)31-93-94-59(3,4)46(53(89)74-37(15-9-23-67-56(61)62)48(84)73-38(49(85)77-45)16-10-24-68-57(63)64)78-50(86)40(28-33-13-7-6-8-14-33)72-44(82)30-70-43(81)29-71-47(83)36(60)27-34-19-21-35(80)22-20-34/h6-8,13-14,19-22,32,36-42,45-46,80H,5,9-12,15-18,23-31,60H2,1-4H3,(H,70,81)(H,71,83)(H,72,82)(H,73,84)(H,74,89)(H,75,88)(H,76,87)(H,77,85)(H,78,86)(H,91,92)(H4,61,62,67)(H4,63,64,68)(H4,65,66,69)/t32-,36-,37+,38-,39-,40-,41+,42+,45+,46-/m0/s1 HQFJNDAJGQZSOD-OPIHQTCISA-N 50040124 CHEMBL414494::Tyr-Gly-Gly-Phe-c((L-Pen)-Arg-Arg-Ile-Arg-Pro-Cys) Mu-type opioid receptor Cavia cutleri 1.3 ChEMBL 10.1021/jm00058a012 10.7270/Q2K936K7 8096246 Kawasaki, AM; Knapp, RJ; Kramer, TH; Walton, A; Wire, WS; Hashimoto, S; Yamamura, HI; Porreca, F; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040124 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040124&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377583 103972185 CHEMBL414494 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062658 CC[C@H](C)[C@H]1NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@@H](CSSC[C@@H](NC(=O)[C@H]2CCCN2C(=O)[C@H](CCCN=C(N)N)NC1=O)C(O)=O)NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C58H88N20O13S2/c1-3-31(2)46-53(88)73-39(14-8-22-68-58(64)65)54(89)77-23-9-15-42(77)51(86)75-41(55(90)91)30-93-92-29-40(50(85)72-37(12-6-20-66-56(60)61)48(83)71-38(49(84)76-46)13-7-21-67-57(62)63)74-52(87)43-25-33-10-4-5-11-34(33)28-78(43)45(81)27-69-44(80)26-70-47(82)36(59)24-32-16-18-35(79)19-17-32/h4-5,10-11,16-19,31,36-43,46,79H,3,6-9,12-15,20-30,59H2,1-2H3,(H,69,80)(H,70,82)(H,71,83)(H,72,85)(H,73,88)(H,74,87)(H,75,86)(H,76,84)(H,90,91)(H4,60,61,66)(H4,62,63,67)(H4,64,65,68)/t31-,36-,37+,38-,39-,40+,41+,42+,43-,46+/m0/s1 HEEVAXACNMUXSY-OUUFHOCZSA-N 50040134 CHEMBL2371443::Tyr-Gly-Gly-(L-Tic)-c(Cys-Arg-Arg-Ile-Arg-Pro-Cys) Mu-type opioid receptor Cavia cutleri 106 ChEMBL 10.1021/jm00058a012 10.7270/Q2K936K7 8096246 Kawasaki, AM; Knapp, RJ; Kramer, TH; Walton, A; Wire, WS; Hashimoto, S; Yamamura, HI; Porreca, F; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040134 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040134&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73350171 103972195 CHEMBL2371443 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062659 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C75H126N24O15/c1-7-45(6)61(70(111)94-53(25-17-35-87-75(83)84)71(112)99-36-18-26-58(99)69(110)93-50(21-11-13-31-76)64(105)96-56(38-44(4)5)67(108)95-54(72(113)114)22-12-14-32-77)98-65(106)52(24-16-34-86-74(81)82)91-63(104)51(23-15-33-85-73(79)80)92-66(107)55(37-43(2)3)97-68(109)57(40-46-19-9-8-10-20-46)90-60(102)42-88-59(101)41-89-62(103)49(78)39-47-27-29-48(100)30-28-47/h8-10,19-20,27-30,43-45,49-58,61,100H,7,11-18,21-26,31-42,76-78H2,1-6H3,(H,88,101)(H,89,103)(H,90,102)(H,91,104)(H,92,107)(H,93,110)(H,94,111)(H,95,108)(H,96,105)(H,97,109)(H,98,106)(H,113,114)(H4,79,80,85)(H4,81,82,86)(H4,83,84,87)/t45-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,61-/m0/s1 OVVIBUHLQIYUEU-IWIISZHXSA-N 224024 BDBM50241435::Dynorphin A (1-13)::YGGFLRRXRPKLK Mu-type opioid receptor Cavia cutleri 1.3 ChEMBL 10.1021/jm00058a012 10.7270/Q2K936K7 8096246 Kawasaki, AM; Knapp, RJ; Kramer, TH; Walton, A; Wire, WS; Hashimoto, S; Yamamura, HI; Porreca, F; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=224024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=224024&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25075996 374884564 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062660 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C63H103N21O13/c1-5-37(4)51(58(94)80-44(20-13-29-74-63(70)71)59(95)84-30-14-21-48(84)57(93)81-45(60(96)97)17-9-10-26-64)83-54(90)43(19-12-28-73-62(68)69)78-53(89)42(18-11-27-72-61(66)67)79-55(91)46(31-36(2)3)82-56(92)47(33-38-15-7-6-8-16-38)77-50(87)35-75-49(86)34-76-52(88)41(65)32-39-22-24-40(85)25-23-39/h6-8,15-16,22-25,36-37,41-48,51,85H,5,9-14,17-21,26-35,64-65H2,1-4H3,(H,75,86)(H,76,88)(H,77,87)(H,78,89)(H,79,91)(H,80,94)(H,81,93)(H,82,92)(H,83,90)(H,96,97)(H4,66,67,72)(H4,68,69,73)(H4,70,71,74)/t37-,41-,42-,43-,44-,45-,46-,47-,48-,51-/m0/s1 WZHQALIQGVYQGG-QFIUEGLPSA-N 50040123 CHEMBL438223::HTry-Gly-Gly-Phe-Leu-Arg-Arg-lle-Arg-Pro-LysOH::Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys::[D-Pro-10]Dyn A-(1-11) Mu-type opioid receptor Cavia cutleri 1.1 ChEMBL 10.1021/jm00058a012 10.7270/Q2K936K7 8096246 Kawasaki, AM; Knapp, RJ; Kramer, TH; Walton, A; Wire, WS; Hashimoto, S; Yamamura, HI; Porreca, F; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040123 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040123&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3086114 103972184 CHEMBL438223 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062661 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CSSC[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC1=O)C(O)=O InChI=1S/C69H111N23O15S2/c1-38(2)30-48(89-62(102)50(33-40-14-6-5-7-15-40)83-55(95)35-81-54(94)34-82-56(96)43(71)32-41-21-23-42(93)24-22-41)60(100)85-45(17-10-26-78-67(72)73)57(97)84-46(18-11-27-79-68(74)75)59(99)90-51-36-108-109-37-52(66(106)107)91-61(101)49(31-39(3)4)88-58(98)44(16-8-9-25-70)86-64(104)53-20-13-29-92(53)65(105)47(87-63(51)103)19-12-28-80-69(76)77/h5-7,14-15,21-24,38-39,43-53,93H,8-13,16-20,25-37,70-71H2,1-4H3,(H,81,94)(H,82,96)(H,83,95)(H,84,97)(H,85,100)(H,86,104)(H,87,103)(H,88,98)(H,89,102)(H,90,99)(H,91,101)(H,106,107)(H4,72,73,78)(H4,74,75,79)(H4,76,77,80)/t43-,44-,45-,46-,47-,48-,49+,50-,51-,52+,53+/m0/s1 CFLNLQMTERLWTF-FTGZPIMJSA-N 50040125 CHEMBL438274::Tyr-Gly-Gly-Phe-Leu-Arg-Arg-c(Cys-Arg-Pro-Lys-Leu-Cys) Mu-type opioid receptor Cavia cutleri 7.3 ChEMBL 10.1021/jm00058a012 10.7270/Q2K936K7 8096246 Kawasaki, AM; Knapp, RJ; Kramer, TH; Walton, A; Wire, WS; Hashimoto, S; Yamamura, HI; Porreca, F; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040125 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040125&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377350 103972186 CHEMBL438274 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062662 CC[C@H](C)[C@@H]1NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CSSC[C@@H](NC(=O)[C@@H](CCCNC(N)=N)NC1=O)C(=O)N[C@@H](CCCCN)C(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C58H93N21O13S2/c1-3-32(2)46-54(90)75-38(16-10-24-68-57(63)64)49(85)77-43(53(89)76-40(55(91)92)14-7-8-22-59)31-94-93-30-42(52(88)74-37(15-9-23-67-56(61)62)48(84)73-39(50(86)79-46)17-11-25-69-58(65)66)78-51(87)41(27-33-12-5-4-6-13-33)72-45(82)29-70-44(81)28-71-47(83)36(60)26-34-18-20-35(80)21-19-34/h4-6,12-13,18-21,32,36-43,46,80H,3,7-11,14-17,22-31,59-60H2,1-2H3,(H,70,81)(H,71,83)(H,72,82)(H,73,84)(H,74,88)(H,75,90)(H,76,89)(H,77,85)(H,78,87)(H,79,86)(H,91,92)(H4,61,62,67)(H4,63,64,68)(H4,65,66,69)/t32-,36-,37-,38+,39+,40-,41-,42+,43+,46-/m0/s1 HCAKSCQUNWRYRV-GCOXHJDASA-N 50040133 CHEMBL444626::Tyr-Gly-Gly-Phe-c(Cys-Arg-Arg-Ile-Arg-Cys)-lys Mu-type opioid receptor Cavia cutleri 4.3 ChEMBL 10.1021/jm00058a012 10.7270/Q2K936K7 8096246 Kawasaki, AM; Knapp, RJ; Kramer, TH; Walton, A; Wire, WS; Hashimoto, S; Yamamura, HI; Porreca, F; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040133 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040133&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377582 103972194 CHEMBL444626 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062666 CC[C@H](C)[C@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CSSC[C@@H](NC(=O)[C@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC1=O)C(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C58H90N20O13S2/c1-4-31(2)45-53(88)74-39(16-10-24-68-58(64)65)54(89)78-25-11-17-43(78)52(87)76-42(55(90)91)30-93-92-29-41(51(86)73-37(14-8-22-66-56(60)61)48(83)72-38(49(84)77-45)15-9-23-67-57(62)63)75-50(85)40(27-33-12-6-5-7-13-33)71-44(80)28-69-46(81)32(3)70-47(82)36(59)26-34-18-20-35(79)21-19-34/h5-7,12-13,18-21,31-32,36-43,45,79H,4,8-11,14-17,22-30,59H2,1-3H3,(H,69,81)(H,70,82)(H,71,80)(H,72,83)(H,73,86)(H,74,88)(H,75,85)(H,76,87)(H,77,84)(H,90,91)(H4,60,61,66)(H4,62,63,67)(H4,64,65,68)/t31-,32+,36-,37+,38-,39-,40-,41+,42+,43+,45+/m0/s1 PMJPFGGZUXOYBP-HNXFJGINSA-N 50040128 CHEMBL384566::Tyr-(D-ala)-Gly-Phe-c(Cys-Arg-Arg-Ile-Arg-Pro-Cys) Mu-type opioid receptor Cavia cutleri 9.7 ChEMBL 10.1021/jm00058a012 10.7270/Q2K936K7 8096246 Kawasaki, AM; Knapp, RJ; Kramer, TH; Walton, A; Wire, WS; Hashimoto, S; Yamamura, HI; Porreca, F; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040128&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377512 103972189 CHEMBL384566 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062667 CC[C@H](C)[C@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CSSC[C@@H](NC(=O)[C@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC1=O)C(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccccc1 InChI=1S/C57H88N20O12S2/c1-3-32(2)45-52(86)73-38(20-12-24-67-57(63)64)53(87)77-25-13-21-42(77)51(85)75-41(54(88)89)31-91-90-30-40(50(84)72-36(18-10-22-65-55(59)60)47(81)71-37(48(82)76-45)19-11-23-66-56(61)62)74-49(83)39(27-34-16-8-5-9-17-34)70-44(79)29-68-43(78)28-69-46(80)35(58)26-33-14-6-4-7-15-33/h4-9,14-17,32,35-42,45H,3,10-13,18-31,58H2,1-2H3,(H,68,78)(H,69,80)(H,70,79)(H,71,81)(H,72,84)(H,73,86)(H,74,83)(H,75,85)(H,76,82)(H,88,89)(H4,59,60,65)(H4,61,62,66)(H4,63,64,67)/t32-,35-,36+,37-,38-,39-,40+,41+,42+,45+/m0/s1 ZWMYGHUEJUXZOJ-XGUZWJOLSA-N 50040129 CHEMBL408497::Phe-Gly-Gly-Phe-c(Cys-Arg-Arg-Ile-Arg-Pro-Cys) Mu-type opioid receptor Cavia cutleri 61 ChEMBL 10.1021/jm00058a012 10.7270/Q2K936K7 8096246 Kawasaki, AM; Knapp, RJ; Kramer, TH; Walton, A; Wire, WS; Hashimoto, S; Yamamura, HI; Porreca, F; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040129&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377511 103972190 CHEMBL408497 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50063734 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1cccc(F)c1)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C37H51FN8O10/c1-18(2)30(36(55)41-17-28(40)48)46-37(56)31(19(3)4)45-35(54)27(16-29(49)50)44-34(53)26(15-22-7-6-8-23(38)13-22)43-32(51)20(5)42-33(52)25(39)14-21-9-11-24(47)12-10-21/h6-13,18-20,25-27,30-31,47H,14-17,39H2,1-5H3,(H2,40,48)(H,41,55)(H,42,52)(H,43,51)(H,44,53)(H,45,54)(H,46,56)(H,49,50)/t20-,25-,26-,27-,30-,31-/m0/s1 YSZYFTORTNQDNC-NKSUJDJASA-N 50034241 (S)-3-[(S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-(3-fluoro-phenyl)-propionylamino]-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL279430 Mu-type opioid receptor Cavia cutleri 3480 ChEMBL 10.1021/jm00007a020 10.7270/Q21835J2 7707326 Heyl, DL; Dandabathula, M; Kurtz, KR; Mousigian, C Eastern Michigan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034241 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034241&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44274482 103942445 CHEMBL279430 ZINC95608301 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50063738 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1c(C)c(C)c(C)c(C)c1C)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C42H62N8O10/c1-19(2)35(41(59)45-18-33(44)52)50-42(60)36(20(3)4)49-40(58)32(17-34(53)54)48-39(57)31(16-29-24(8)22(6)21(5)23(7)25(29)9)47-37(55)26(10)46-38(56)30(43)15-27-11-13-28(51)14-12-27/h11-14,19-20,26,30-32,35-36,51H,15-18,43H2,1-10H3,(H2,44,52)(H,45,59)(H,46,56)(H,47,55)(H,48,57)(H,49,58)(H,50,60)(H,53,54)/t26-,30-,31-,32-,35-,36-/m0/s1 GLVGLEWNIBLSII-JMJHPKHCSA-N 50034243 (S)-3-((S)-2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-pentamethylphenyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL281634 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm00007a020 10.7270/Q21835J2 7707326 Heyl, DL; Dandabathula, M; Kurtz, KR; Mousigian, C Eastern Michigan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034243 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034243&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44274467 103942447 CHEMBL281634 ZINC95542521 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062669 CC[C@H](C)[C@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CSSC[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC1=O)C(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C69H111N23O15S2/c1-5-39(4)55-64(104)87-47(20-13-29-80-69(76)77)65(105)92-30-14-21-52(92)63(103)86-44(17-9-10-26-70)58(98)88-48(31-38(2)3)60(100)90-51(66(106)107)37-109-108-36-50(62(102)85-45(18-11-27-78-67(72)73)57(97)84-46(59(99)91-55)19-12-28-79-68(74)75)89-61(101)49(33-40-15-7-6-8-16-40)83-54(95)35-81-53(94)34-82-56(96)43(71)32-41-22-24-42(93)25-23-41/h6-8,15-16,22-25,38-39,43-52,55,93H,5,9-14,17-21,26-37,70-71H2,1-4H3,(H,81,94)(H,82,96)(H,83,95)(H,84,97)(H,85,102)(H,86,103)(H,87,104)(H,88,98)(H,89,101)(H,90,100)(H,91,99)(H,106,107)(H4,72,73,78)(H4,74,75,79)(H4,76,77,80)/t39-,43-,44-,45+,46-,47-,48+,49-,50+,51+,52-,55+/m0/s1 GRCXYAMUGBVXNL-ZCKMNMIQSA-N 50040132 CHEMBL411196::Tyr-Gly-Gly-Phe-c(Cys-Arg-Arg-Ile-Arg-(D-Pro)-Lys-Leu-Cys) Mu-type opioid receptor Cavia cutleri 2.5 ChEMBL 10.1021/jm00058a012 10.7270/Q2K936K7 8096246 Kawasaki, AM; Knapp, RJ; Kramer, TH; Walton, A; Wire, WS; Hashimoto, S; Yamamura, HI; Porreca, F; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040132&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377703 103972193 CHEMBL411196 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062670 CC[C@H](C)[C@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CSSC[C@@H](NC1=O)C(=O)N1CCC[C@@H]1C(=O)N[C@H](CCCCN)C(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C57H88N18O13S2/c1-3-32(2)46-53(85)73-42(54(86)75-25-11-17-43(75)52(84)71-39(55(87)88)14-7-8-22-58)31-90-89-30-41(51(83)70-37(15-9-23-64-56(60)61)48(80)69-38(49(81)74-46)16-10-24-65-57(62)63)72-50(82)40(27-33-12-5-4-6-13-33)68-45(78)29-66-44(77)28-67-47(79)36(59)26-34-18-20-35(76)21-19-34/h4-6,12-13,18-21,32,36-43,46,76H,3,7-11,14-17,22-31,58-59H2,1-2H3,(H,66,77)(H,67,79)(H,68,78)(H,69,80)(H,70,83)(H,71,84)(H,72,82)(H,73,85)(H,74,81)(H,87,88)(H4,60,61,64)(H4,62,63,65)/t32-,36-,37+,38-,39+,40-,41+,42+,43+,46+/m0/s1 HVMQYPHUUJTRGD-NQPDJVKOSA-N 50040127 CHEMBL386722::Tyr-Gly-Gly-Phe-c(Cys-Arg-Arg-Ile-Cys)-Pro-lys Mu-type opioid receptor Cavia cutleri 6.4 ChEMBL 10.1021/jm00058a012 10.7270/Q2K936K7 8096246 Kawasaki, AM; Knapp, RJ; Kramer, TH; Walton, A; Wire, WS; Hashimoto, S; Yamamura, HI; Porreca, F; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040127 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040127&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377510 103972188 CHEMBL386722 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062672 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]1CSSC[C@H](NC(=O)[C@@H](CCCCN)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](CCCNC(N)=N)NC1=O)C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C69H112N24O15S2/c1-39(2)32-49(90-61(102)50(34-40-14-4-3-5-15-40)84-55(96)36-82-54(95)35-83-56(97)43(72)33-41-22-24-42(94)25-23-41)60(101)86-45(18-10-28-79-67(73)74)57(98)85-46(19-11-29-80-68(75)76)59(100)91-51-37-109-110-38-52(63(104)89-48(66(107)108)17-7-9-27-71)92-58(99)44(16-6-8-26-70)87-64(105)53-21-13-31-93(53)65(106)47(88-62(51)103)20-12-30-81-69(77)78/h3-5,14-15,22-25,39,43-53,94H,6-13,16-21,26-38,70-72H2,1-2H3,(H,82,95)(H,83,97)(H,84,96)(H,85,98)(H,86,101)(H,87,105)(H,88,103)(H,89,104)(H,90,102)(H,91,100)(H,92,99)(H,107,108)(H4,73,74,79)(H4,75,76,80)(H4,77,78,81)/t43-,44+,45-,46-,47+,48-,49-,50-,51+,52-,53-/m0/s1 ZKABMENGQLCEDM-HHYGOIQTSA-N 50040131 CHEMBL409793::Tyr-Gly-Gly-Phe-Leu-Arg-Arg-c((D-Cys)-Arg-Pro-Lys-(D-Cys))-Lys Mu-type opioid receptor Cavia cutleri 0.674000 ChEMBL 10.1021/jm00058a012 10.7270/Q2K936K7 8096246 Kawasaki, AM; Knapp, RJ; Kramer, TH; Walton, A; Wire, WS; Hashimoto, S; Yamamura, HI; Porreca, F; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040131&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377704 103972192 CHEMBL409793 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062674 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CSSC[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC1=O)C(O)=O InChI=1S/C69H111N23O15S2/c1-38(2)30-48(89-62(102)50(33-40-14-6-5-7-15-40)83-55(95)35-81-54(94)34-82-56(96)43(71)32-41-21-23-42(93)24-22-41)60(100)85-45(17-10-26-78-67(72)73)57(97)84-46(18-11-27-79-68(74)75)59(99)90-51-36-108-109-37-52(66(106)107)91-61(101)49(31-39(3)4)88-58(98)44(16-8-9-25-70)86-64(104)53-20-13-29-92(53)65(105)47(87-63(51)103)19-12-28-80-69(76)77/h5-7,14-15,21-24,38-39,43-53,93H,8-13,16-20,25-37,70-71H2,1-4H3,(H,81,94)(H,82,96)(H,83,95)(H,84,97)(H,85,100)(H,86,104)(H,87,103)(H,88,98)(H,89,102)(H,90,99)(H,91,101)(H,106,107)(H4,72,73,78)(H4,74,75,79)(H4,76,77,80)/t43-,44-,45-,46-,47-,48-,49+,50-,51-,52+,53+/m0/s1 CFLNLQMTERLWTF-FTGZPIMJSA-N 50040125 CHEMBL438274::Tyr-Gly-Gly-Phe-Leu-Arg-Arg-c(Cys-Arg-Pro-Lys-Leu-Cys) Mu-type opioid receptor Cavia cutleri 0.380000 ChEMBL 10.1021/jm00058a012 10.7270/Q2K936K7 8096246 Kawasaki, AM; Knapp, RJ; Kramer, TH; Walton, A; Wire, WS; Hashimoto, S; Yamamura, HI; Porreca, F; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040125 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040125&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377350 103972186 CHEMBL438274 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062682 CC[C@H](C)[C@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CSSC[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC1=O)C(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C69H111N23O15S2/c1-5-39(4)55-64(104)87-47(20-13-29-80-69(76)77)65(105)92-30-14-21-52(92)63(103)86-44(17-9-10-26-70)58(98)88-48(31-38(2)3)60(100)90-51(66(106)107)37-109-108-36-50(62(102)85-45(18-11-27-78-67(72)73)57(97)84-46(59(99)91-55)19-12-28-79-68(74)75)89-61(101)49(33-40-15-7-6-8-16-40)83-54(95)35-81-53(94)34-82-56(96)43(71)32-41-22-24-42(93)25-23-41/h6-8,15-16,22-25,38-39,43-52,55,93H,5,9-14,17-21,26-37,70-71H2,1-4H3,(H,81,94)(H,82,96)(H,83,95)(H,84,97)(H,85,102)(H,86,103)(H,87,104)(H,88,98)(H,89,101)(H,90,100)(H,91,99)(H,106,107)(H4,72,73,78)(H4,74,75,79)(H4,76,77,80)/t39-,43-,44-,45+,46-,47-,48+,49-,50+,51+,52-,55+/m0/s1 GRCXYAMUGBVXNL-ZCKMNMIQSA-N 50040132 CHEMBL411196::Tyr-Gly-Gly-Phe-c(Cys-Arg-Arg-Ile-Arg-(D-Pro)-Lys-Leu-Cys) Mu-type opioid receptor Cavia cutleri 25 ChEMBL 10.1021/jm00058a012 10.7270/Q2K936K7 8096246 Kawasaki, AM; Knapp, RJ; Kramer, TH; Walton, A; Wire, WS; Hashimoto, S; Yamamura, HI; Porreca, F; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040132&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377703 103972193 CHEMBL411196 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062683 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]1CSSC[C@H](NC(=O)[C@@H](CCCCN)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](CCCNC(N)=N)NC1=O)C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C69H112N24O15S2/c1-39(2)32-49(90-61(102)50(34-40-14-4-3-5-15-40)84-55(96)36-82-54(95)35-83-56(97)43(72)33-41-22-24-42(94)25-23-41)60(101)86-45(18-10-28-79-67(73)74)57(98)85-46(19-11-29-80-68(75)76)59(100)91-51-37-109-110-38-52(63(104)89-48(66(107)108)17-7-9-27-71)92-58(99)44(16-6-8-26-70)87-64(105)53-21-13-31-93(53)65(106)47(88-62(51)103)20-12-30-81-69(77)78/h3-5,14-15,22-25,39,43-53,94H,6-13,16-21,26-38,70-72H2,1-2H3,(H,82,95)(H,83,97)(H,84,96)(H,85,98)(H,86,101)(H,87,105)(H,88,103)(H,89,104)(H,90,102)(H,91,100)(H,92,99)(H,107,108)(H4,73,74,79)(H4,75,76,80)(H4,77,78,81)/t43-,44+,45-,46-,47+,48-,49-,50-,51+,52-,53-/m0/s1 ZKABMENGQLCEDM-HHYGOIQTSA-N 50040131 CHEMBL409793::Tyr-Gly-Gly-Phe-Leu-Arg-Arg-c((D-Cys)-Arg-Pro-Lys-(D-Cys))-Lys Mu-type opioid receptor Cavia cutleri 4.5 ChEMBL 10.1021/jm00058a012 10.7270/Q2K936K7 8096246 Kawasaki, AM; Knapp, RJ; Kramer, TH; Walton, A; Wire, WS; Hashimoto, S; Yamamura, HI; Porreca, F; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040131&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377704 103972192 CHEMBL409793 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062687 CC[C@H](C)[C@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC1=O)C(=O)N[C@@H](CCCCN)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C58H92N18O13S2/c1-5-33(4)47-55(87)71-38(16-11-23-65-57(61)62)49(81)74-44(54(86)72-40(56(88)89)15-9-10-22-59)31-91-90-30-43(53(85)70-39(50(82)76-47)17-12-24-66-58(63)64)75-51(83)41(25-32(2)3)73-52(84)42(27-34-13-7-6-8-14-34)69-46(79)29-67-45(78)28-68-48(80)37(60)26-35-18-20-36(77)21-19-35/h6-8,13-14,18-21,32-33,37-44,47,77H,5,9-12,15-17,22-31,59-60H2,1-4H3,(H,67,78)(H,68,80)(H,69,79)(H,70,85)(H,71,87)(H,72,86)(H,73,84)(H,74,81)(H,75,83)(H,76,82)(H,88,89)(H4,61,62,65)(H4,63,64,66)/t33-,37-,38-,39-,40-,41-,42-,43-,44-,47+/m0/s1 JYEKWXODJFQZIP-HSIOXNDMSA-N 50040126 CHEMBL265241::Tyr-Gly-Gly-Phe-leu-c(Cys-Arg-Ile-Arg-Cys)-lys Mu-type opioid receptor Cavia cutleri 6.5 ChEMBL 10.1021/jm00058a012 10.7270/Q2K936K7 8096246 Kawasaki, AM; Knapp, RJ; Kramer, TH; Walton, A; Wire, WS; Hashimoto, S; Yamamura, HI; Porreca, F; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040126 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040126&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377415 103972187 CHEMBL265241 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062689 CC[C@H](C)[C@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CSSC[C@@H](NC1=O)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H](CCCCN)C(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C58H93N21O13S2/c1-3-32(2)46-54(90)78-43(53(89)75-38(16-10-24-68-57(63)64)49(85)76-40(55(91)92)14-7-8-22-59)31-94-93-30-42(52(88)74-37(15-9-23-67-56(61)62)48(84)73-39(50(86)79-46)17-11-25-69-58(65)66)77-51(87)41(27-33-12-5-4-6-13-33)72-45(82)29-70-44(81)28-71-47(83)36(60)26-34-18-20-35(80)21-19-34/h4-6,12-13,18-21,32,36-43,46,80H,3,7-11,14-17,22-31,59-60H2,1-2H3,(H,70,81)(H,71,83)(H,72,82)(H,73,84)(H,74,88)(H,75,89)(H,76,85)(H,77,87)(H,78,90)(H,79,86)(H,91,92)(H4,61,62,67)(H4,63,64,68)(H4,65,66,69)/t32-,36-,37+,38+,39-,40+,41-,42+,43+,46+/m0/s1 MRWXDNZOCJXRHP-KCSCKQEISA-N 50040130 CHEMBL415406::Tyr-Gly-Gly-Phe-c(Cys-Arg-Arg-Ile-Cys)-Arg-lys Mu-type opioid receptor Cavia cutleri 250 ChEMBL 10.1021/jm00058a012 10.7270/Q2K936K7 8096246 Kawasaki, AM; Knapp, RJ; Kramer, TH; Walton, A; Wire, WS; Hashimoto, S; Yamamura, HI; Porreca, F; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040130&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377416 103972191 CHEMBL415406 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062690 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(O)=O InChI=1S/C99H155N31O23/c1-7-55(6)81(129-86(142)66(28-18-40-112-98(107)108)118-83(139)65(27-17-39-111-97(105)106)120-88(144)70(44-54(4)5)125-89(145)71(46-56-21-9-8-10-22-56)117-79(135)52-115-78(134)51-116-82(138)61(102)45-57-31-33-59(131)34-32-57)94(150)122-67(29-19-41-113-99(109)110)95(151)130-42-20-30-75(130)93(149)121-64(26-14-16-38-101)85(141)124-69(43-53(2)3)87(143)119-63(25-13-15-37-100)84(140)126-72(47-58-50-114-62-24-12-11-23-60(58)62)90(146)128-74(49-80(136)137)92(148)127-73(48-77(104)133)91(147)123-68(96(152)153)35-36-76(103)132/h8-12,21-24,31-34,50,53-55,61,63-75,81,114,131H,7,13-20,25-30,35-49,51-52,100-102H2,1-6H3,(H2,103,132)(H2,104,133)(H,115,134)(H,116,138)(H,117,135)(H,118,139)(H,119,143)(H,120,144)(H,121,149)(H,122,150)(H,123,147)(H,124,141)(H,125,145)(H,126,140)(H,127,148)(H,128,146)(H,129,142)(H,136,137)(H,152,153)(H4,105,106,111)(H4,107,108,112)(H4,109,110,113)/t55-,61-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,81-/m0/s1 JMNJYGMAUMANNW-FIXZTSJVSA-N 50010702 CHEMBL411557::DYNORPHIN(1-17)-OH::Dynorphin A (1-17)::H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln-OH::Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln::dynorphin A Mu-type opioid receptor Cavia cutleri 2.5 ChEMBL 10.1021/jm00058a012 10.7270/Q2K936K7 8096246 Kawasaki, AM; Knapp, RJ; Kramer, TH; Walton, A; Wire, WS; Hashimoto, S; Yamamura, HI; Porreca, F; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010702&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 91928823 103923448 CHEMBL411557 C02716 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062691 CC[C@H](C)[C@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC1=O)C(=O)N[C@@H](CCCCN)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C58H92N18O13S2/c1-5-33(4)47-55(87)71-38(16-11-23-65-57(61)62)49(81)74-44(54(86)72-40(56(88)89)15-9-10-22-59)31-91-90-30-43(53(85)70-39(50(82)76-47)17-12-24-66-58(63)64)75-51(83)41(25-32(2)3)73-52(84)42(27-34-13-7-6-8-14-34)69-46(79)29-67-45(78)28-68-48(80)37(60)26-35-18-20-36(77)21-19-35/h6-8,13-14,18-21,32-33,37-44,47,77H,5,9-12,15-17,22-31,59-60H2,1-4H3,(H,67,78)(H,68,80)(H,69,79)(H,70,85)(H,71,87)(H,72,86)(H,73,84)(H,74,81)(H,75,83)(H,76,82)(H,88,89)(H4,61,62,65)(H4,63,64,66)/t33-,37-,38-,39-,40-,41-,42-,43-,44-,47+/m0/s1 JYEKWXODJFQZIP-HSIOXNDMSA-N 50040126 CHEMBL265241::Tyr-Gly-Gly-Phe-leu-c(Cys-Arg-Ile-Arg-Cys)-lys Mu-type opioid receptor Cavia cutleri 0.091000 ChEMBL 10.1021/jm00058a012 10.7270/Q2K936K7 8096246 Kawasaki, AM; Knapp, RJ; Kramer, TH; Walton, A; Wire, WS; Hashimoto, S; Yamamura, HI; Porreca, F; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040126 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040126&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377415 103972187 CHEMBL265241 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062692 CC[C@H](C)[C@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CSSC[C@@H](NC1=O)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H](CCCCN)C(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C58H93N21O13S2/c1-3-32(2)46-54(90)78-43(53(89)75-38(16-10-24-68-57(63)64)49(85)76-40(55(91)92)14-7-8-22-59)31-94-93-30-42(52(88)74-37(15-9-23-67-56(61)62)48(84)73-39(50(86)79-46)17-11-25-69-58(65)66)77-51(87)41(27-33-12-5-4-6-13-33)72-45(82)29-70-44(81)28-71-47(83)36(60)26-34-18-20-35(80)21-19-34/h4-6,12-13,18-21,32,36-43,46,80H,3,7-11,14-17,22-31,59-60H2,1-2H3,(H,70,81)(H,71,83)(H,72,82)(H,73,84)(H,74,88)(H,75,89)(H,76,85)(H,77,87)(H,78,90)(H,79,86)(H,91,92)(H4,61,62,67)(H4,63,64,68)(H4,65,66,69)/t32-,36-,37+,38+,39-,40+,41-,42+,43+,46+/m0/s1 MRWXDNZOCJXRHP-KCSCKQEISA-N 50040130 CHEMBL415406::Tyr-Gly-Gly-Phe-c(Cys-Arg-Arg-Ile-Cys)-Arg-lys Mu-type opioid receptor Cavia cutleri 5.8 ChEMBL 10.1021/jm00058a012 10.7270/Q2K936K7 8096246 Kawasaki, AM; Knapp, RJ; Kramer, TH; Walton, A; Wire, WS; Hashimoto, S; Yamamura, HI; Porreca, F; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040130&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377416 103972191 CHEMBL415406 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062694 CC[C@H](C)[C@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SSC[C@@H](NC(=O)[C@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC1=O)C(O)=O InChI=1S/C59H92N20O13S2/c1-5-32(2)45-52(88)75-39(17-11-25-69-58(65)66)54(90)79-26-12-18-42(79)51(87)76-41(55(91)92)31-93-94-59(3,4)46(53(89)74-37(15-9-23-67-56(61)62)48(84)73-38(49(85)77-45)16-10-24-68-57(63)64)78-50(86)40(28-33-13-7-6-8-14-33)72-44(82)30-70-43(81)29-71-47(83)36(60)27-34-19-21-35(80)22-20-34/h6-8,13-14,19-22,32,36-42,45-46,80H,5,9-12,15-18,23-31,60H2,1-4H3,(H,70,81)(H,71,83)(H,72,82)(H,73,84)(H,74,89)(H,75,88)(H,76,87)(H,77,85)(H,78,86)(H,91,92)(H4,61,62,67)(H4,63,64,68)(H4,65,66,69)/t32-,36-,37+,38-,39-,40-,41+,42+,45+,46-/m0/s1 HQFJNDAJGQZSOD-OPIHQTCISA-N 50040124 CHEMBL414494::Tyr-Gly-Gly-Phe-c((L-Pen)-Arg-Arg-Ile-Arg-Pro-Cys) Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm00058a012 10.7270/Q2K936K7 8096246 Kawasaki, AM; Knapp, RJ; Kramer, TH; Walton, A; Wire, WS; Hashimoto, S; Yamamura, HI; Porreca, F; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040124 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040124&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377583 103972185 CHEMBL414494 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062695 CC[C@H](C)[C@@H]1NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CSSC[C@@H](NC(=O)[C@@H](CCCNC(N)=N)NC1=O)C(=O)N[C@@H](CCCCN)C(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C58H93N21O13S2/c1-3-32(2)46-54(90)75-38(16-10-24-68-57(63)64)49(85)77-43(53(89)76-40(55(91)92)14-7-8-22-59)31-94-93-30-42(52(88)74-37(15-9-23-67-56(61)62)48(84)73-39(50(86)79-46)17-11-25-69-58(65)66)78-51(87)41(27-33-12-5-4-6-13-33)72-45(82)29-70-44(81)28-71-47(83)36(60)26-34-18-20-35(80)21-19-34/h4-6,12-13,18-21,32,36-43,46,80H,3,7-11,14-17,22-31,59-60H2,1-2H3,(H,70,81)(H,71,83)(H,72,82)(H,73,84)(H,74,88)(H,75,90)(H,76,89)(H,77,85)(H,78,87)(H,79,86)(H,91,92)(H4,61,62,67)(H4,63,64,68)(H4,65,66,69)/t32-,36-,37-,38+,39+,40-,41-,42+,43+,46-/m0/s1 HCAKSCQUNWRYRV-GCOXHJDASA-N 50040133 CHEMBL444626::Tyr-Gly-Gly-Phe-c(Cys-Arg-Arg-Ile-Arg-Cys)-lys Mu-type opioid receptor Cavia cutleri 286 ChEMBL 10.1021/jm00058a012 10.7270/Q2K936K7 8096246 Kawasaki, AM; Knapp, RJ; Kramer, TH; Walton, A; Wire, WS; Hashimoto, S; Yamamura, HI; Porreca, F; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040133 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040133&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377582 103972194 CHEMBL444626 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062699 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C75H126N24O15/c1-7-45(6)61(70(111)94-53(25-17-35-87-75(83)84)71(112)99-36-18-26-58(99)69(110)93-50(21-11-13-31-76)64(105)96-56(38-44(4)5)67(108)95-54(72(113)114)22-12-14-32-77)98-65(106)52(24-16-34-86-74(81)82)91-63(104)51(23-15-33-85-73(79)80)92-66(107)55(37-43(2)3)97-68(109)57(40-46-19-9-8-10-20-46)90-60(102)42-88-59(101)41-89-62(103)49(78)39-47-27-29-48(100)30-28-47/h8-10,19-20,27-30,43-45,49-58,61,100H,7,11-18,21-26,31-42,76-78H2,1-6H3,(H,88,101)(H,89,103)(H,90,102)(H,91,104)(H,92,107)(H,93,110)(H,94,111)(H,95,108)(H,96,105)(H,97,109)(H,98,106)(H,113,114)(H4,79,80,85)(H4,81,82,86)(H4,83,84,87)/t45-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,61-/m0/s1 OVVIBUHLQIYUEU-IWIISZHXSA-N 224024 BDBM50241435::Dynorphin A (1-13)::YGGFLRRXRPKLK Mu-type opioid receptor Cavia cutleri 1.2 ChEMBL 10.1021/jm00058a012 10.7270/Q2K936K7 8096246 Kawasaki, AM; Knapp, RJ; Kramer, TH; Walton, A; Wire, WS; Hashimoto, S; Yamamura, HI; Porreca, F; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=224024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=224024&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25075996 374884564 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062702 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(O)=O InChI=1S/C99H155N31O23/c1-7-55(6)81(129-86(142)66(28-18-40-112-98(107)108)118-83(139)65(27-17-39-111-97(105)106)120-88(144)70(44-54(4)5)125-89(145)71(46-56-21-9-8-10-22-56)117-79(135)52-115-78(134)51-116-82(138)61(102)45-57-31-33-59(131)34-32-57)94(150)122-67(29-19-41-113-99(109)110)95(151)130-42-20-30-75(130)93(149)121-64(26-14-16-38-101)85(141)124-69(43-53(2)3)87(143)119-63(25-13-15-37-100)84(140)126-72(47-58-50-114-62-24-12-11-23-60(58)62)90(146)128-74(49-80(136)137)92(148)127-73(48-77(104)133)91(147)123-68(96(152)153)35-36-76(103)132/h8-12,21-24,31-34,50,53-55,61,63-75,81,114,131H,7,13-20,25-30,35-49,51-52,100-102H2,1-6H3,(H2,103,132)(H2,104,133)(H,115,134)(H,116,138)(H,117,135)(H,118,139)(H,119,143)(H,120,144)(H,121,149)(H,122,150)(H,123,147)(H,124,141)(H,125,145)(H,126,140)(H,127,148)(H,128,146)(H,129,142)(H,136,137)(H,152,153)(H4,105,106,111)(H4,107,108,112)(H4,109,110,113)/t55-,61-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,81-/m0/s1 JMNJYGMAUMANNW-FIXZTSJVSA-N 50010702 CHEMBL411557::DYNORPHIN(1-17)-OH::Dynorphin A (1-17)::H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln-OH::Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln::dynorphin A Mu-type opioid receptor Cavia cutleri 5 ChEMBL 10.1021/jm00058a012 10.7270/Q2K936K7 8096246 Kawasaki, AM; Knapp, RJ; Kramer, TH; Walton, A; Wire, WS; Hashimoto, S; Yamamura, HI; Porreca, F; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010702&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 91928823 103923448 CHEMBL411557 C02716 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062707 CC[C@H](C)[C@H]1NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@@H](CSSC[C@@H](NC(=O)[C@H]2CCCN2C(=O)[C@H](CCCN=C(N)N)NC1=O)C(O)=O)NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C58H88N20O13S2/c1-3-31(2)46-53(88)73-39(14-8-22-68-58(64)65)54(89)77-23-9-15-42(77)51(86)75-41(55(90)91)30-93-92-29-40(50(85)72-37(12-6-20-66-56(60)61)48(83)71-38(49(84)76-46)13-7-21-67-57(62)63)74-52(87)43-25-33-10-4-5-11-34(33)28-78(43)45(81)27-69-44(80)26-70-47(82)36(59)24-32-16-18-35(79)19-17-32/h4-5,10-11,16-19,31,36-43,46,79H,3,6-9,12-15,20-30,59H2,1-2H3,(H,69,80)(H,70,82)(H,71,83)(H,72,85)(H,73,88)(H,74,87)(H,75,86)(H,76,84)(H,90,91)(H4,60,61,66)(H4,62,63,67)(H4,64,65,68)/t31-,36-,37+,38-,39-,40+,41+,42+,43-,46+/m0/s1 HEEVAXACNMUXSY-OUUFHOCZSA-N 50040134 CHEMBL2371443::Tyr-Gly-Gly-(L-Tic)-c(Cys-Arg-Arg-Ile-Arg-Pro-Cys) Mu-type opioid receptor Cavia cutleri 6180 ChEMBL 10.1021/jm00058a012 10.7270/Q2K936K7 8096246 Kawasaki, AM; Knapp, RJ; Kramer, TH; Walton, A; Wire, WS; Hashimoto, S; Yamamura, HI; Porreca, F; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040134 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040134&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73350171 103972195 CHEMBL2371443 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062709 CC[C@H](C)[C@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CSSC[C@@H](NC1=O)C(=O)N1CCC[C@@H]1C(=O)N[C@H](CCCCN)C(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C57H88N18O13S2/c1-3-32(2)46-53(85)73-42(54(86)75-25-11-17-43(75)52(84)71-39(55(87)88)14-7-8-22-58)31-90-89-30-41(51(83)70-37(15-9-23-64-56(60)61)48(80)69-38(49(81)74-46)16-10-24-65-57(62)63)72-50(82)40(27-33-12-5-4-6-13-33)68-45(78)29-66-44(77)28-67-47(79)36(59)26-34-18-20-35(76)21-19-34/h4-6,12-13,18-21,32,36-43,46,76H,3,7-11,14-17,22-31,58-59H2,1-2H3,(H,66,77)(H,67,79)(H,68,78)(H,69,80)(H,70,83)(H,71,84)(H,72,82)(H,73,85)(H,74,81)(H,87,88)(H4,60,61,64)(H4,62,63,65)/t32-,36-,37+,38-,39+,40-,41+,42+,43+,46+/m0/s1 HVMQYPHUUJTRGD-NQPDJVKOSA-N 50040127 CHEMBL386722::Tyr-Gly-Gly-Phe-c(Cys-Arg-Arg-Ile-Cys)-Pro-lys Mu-type opioid receptor Cavia cutleri 411 ChEMBL 10.1021/jm00058a012 10.7270/Q2K936K7 8096246 Kawasaki, AM; Knapp, RJ; Kramer, TH; Walton, A; Wire, WS; Hashimoto, S; Yamamura, HI; Porreca, F; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040127 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040127&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377510 103972188 CHEMBL386722 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062712 CC[C@H](C)[C@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CSSC[C@@H](NC(=O)[C@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC1=O)C(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C58H90N20O13S2/c1-4-31(2)45-53(88)74-39(16-10-24-68-58(64)65)54(89)78-25-11-17-43(78)52(87)76-42(55(90)91)30-93-92-29-41(51(86)73-37(14-8-22-66-56(60)61)48(83)72-38(49(84)77-45)15-9-23-67-57(62)63)75-50(85)40(27-33-12-6-5-7-13-33)71-44(80)28-69-46(81)32(3)70-47(82)36(59)26-34-18-20-35(79)21-19-34/h5-7,12-13,18-21,31-32,36-43,45,79H,4,8-11,14-17,22-30,59H2,1-3H3,(H,69,81)(H,70,82)(H,71,80)(H,72,83)(H,73,86)(H,74,88)(H,75,85)(H,76,87)(H,77,84)(H,90,91)(H4,60,61,66)(H4,62,63,67)(H4,64,65,68)/t31-,32+,36-,37+,38-,39-,40-,41+,42+,43+,45+/m0/s1 PMJPFGGZUXOYBP-HNXFJGINSA-N 50040128 CHEMBL384566::Tyr-(D-ala)-Gly-Phe-c(Cys-Arg-Arg-Ile-Arg-Pro-Cys) Mu-type opioid receptor Cavia cutleri 3972 ChEMBL 10.1021/jm00058a012 10.7270/Q2K936K7 8096246 Kawasaki, AM; Knapp, RJ; Kramer, TH; Walton, A; Wire, WS; Hashimoto, S; Yamamura, HI; Porreca, F; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040128&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377512 103972189 CHEMBL384566 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062713 CC[C@H](C)[C@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CSSC[C@@H](NC(=O)[C@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC1=O)C(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccccc1 InChI=1S/C57H88N20O12S2/c1-3-32(2)45-52(86)73-38(20-12-24-67-57(63)64)53(87)77-25-13-21-42(77)51(85)75-41(54(88)89)31-91-90-30-40(50(84)72-36(18-10-22-65-55(59)60)47(81)71-37(48(82)76-45)19-11-23-66-56(61)62)74-49(83)39(27-34-16-8-5-9-17-34)70-44(79)29-68-43(78)28-69-46(80)35(58)26-33-14-6-4-7-15-33/h4-9,14-17,32,35-42,45H,3,10-13,18-31,58H2,1-2H3,(H,68,78)(H,69,80)(H,70,79)(H,71,81)(H,72,84)(H,73,86)(H,74,83)(H,75,85)(H,76,82)(H,88,89)(H4,59,60,65)(H4,61,62,66)(H4,63,64,67)/t32-,35-,36+,37-,38-,39-,40+,41+,42+,45+/m0/s1 ZWMYGHUEJUXZOJ-XGUZWJOLSA-N 50040129 CHEMBL408497::Phe-Gly-Gly-Phe-c(Cys-Arg-Arg-Ile-Arg-Pro-Cys) Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm00058a012 10.7270/Q2K936K7 8096246 Kawasaki, AM; Knapp, RJ; Kramer, TH; Walton, A; Wire, WS; Hashimoto, S; Yamamura, HI; Porreca, F; Burks, TF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040129&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377511 103972190 CHEMBL408497 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062827 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C37H52N8O10/c1-19(2)30(36(54)40-18-28(39)47)45-37(55)31(20(3)4)44-35(53)27(17-29(48)49)43-34(52)26(16-22-9-7-6-8-10-22)42-32(50)21(5)41-33(51)25(38)15-23-11-13-24(46)14-12-23/h6-14,19-21,25-27,30-31,46H,15-18,38H2,1-5H3,(H2,39,47)(H,40,54)(H,41,51)(H,42,50)(H,43,52)(H,44,53)(H,45,55)(H,48,49)/t21-,25+,26+,27+,30+,31+/m1/s1 CJAORFIPPWIGPG-QXYJMILXSA-N 50001468 (S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::3-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL317956::H-Tyr-D-Ala-Phe-Asp-Val-Val-Gly-NH2::deltorphin C Mu-type opioid receptor Cavia cutleri 2890 ChEMBL 10.1021/jm00027a017 10.7270/Q2F47N7P 8289187 Misicka, A; Lipkowski, AW; Horvath, R; Davis, P; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001468&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10055958 103915933 CHEMBL317956 C18097 ZINC95610551 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062843 CC1(C)SSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H]1NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C28H35N5O7S2/c1-28(2)23(33-24(36)19(29)12-17-8-10-18(34)11-9-17)26(38)30-14-22(35)31-20(13-16-6-4-3-5-7-16)25(37)32-21(27(39)40)15-41-42-28/h3-11,19-21,23,34H,12-15,29H2,1-2H3,(H,30,38)(H,31,35)(H,32,37)(H,33,36)(H,39,40)/t19-,20-,21-,23-/m0/s1 JMRAKKZUPDWVTJ-FKEBYFGASA-N 50453313 CHEMBL2372329 Mu-type opioid receptor Cavia cutleri 210 ChEMBL 10.1021/jm00027a018 10.7270/Q2TX3G09 8289188 Bartosz-Bechowski, H; Davis, P; Zalewska, T; Slaninova, J; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453313 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453313&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73347170 225145904 CHEMBL2372329 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062850 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C37H52N8O10/c1-19(2)30(36(54)40-18-28(39)47)45-37(55)31(20(3)4)44-35(53)27(17-29(48)49)43-34(52)26(16-22-9-7-6-8-10-22)42-32(50)21(5)41-33(51)25(38)15-23-11-13-24(46)14-12-23/h6-14,19-21,25-27,30-31,46H,15-18,38H2,1-5H3,(H2,39,47)(H,40,54)(H,41,51)(H,42,50)(H,43,52)(H,44,53)(H,45,55)(H,48,49)/t21-,25+,26+,27+,30+,31+/m1/s1 CJAORFIPPWIGPG-QXYJMILXSA-N 50001468 (S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::3-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL317956::H-Tyr-D-Ala-Phe-Asp-Val-Val-Gly-NH2::deltorphin C Mu-type opioid receptor Cavia cutleri >1500 ChEMBL 10.1021/jm00027a018 10.7270/Q2TX3G09 8289188 Bartosz-Bechowski, H; Davis, P; Zalewska, T; Slaninova, J; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001468&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10055958 103915933 CHEMBL317956 C18097 ZINC95610551 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062853 CC1(C)SSC[C@H](NC(=O)[C@H](Cc2ccc(I)cc2)NC(=O)CNC(=O)[C@@H]1NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O InChI=1S/C37H43IN6O8S2/c1-37(2)31(44-32(47)26(39)16-22-10-14-25(45)15-11-22)35(50)40-19-30(46)41-27(17-23-8-12-24(38)13-9-23)33(48)43-29(20-53-54-37)34(49)42-28(36(51)52)18-21-6-4-3-5-7-21/h3-15,26-29,31,45H,16-20,39H2,1-2H3,(H,40,50)(H,41,46)(H,42,49)(H,43,48)(H,44,47)(H,51,52)/t26-,27-,28-,29-,31-/m0/s1 SLRIOOLBTDCCPO-OLAIZJASSA-N 50043723 (S)-2-{[(4R,7S)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-(4-iodo-benzyl)-14,14-dimethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carbonyl]-amino}-3-phenyl-propionic acid::CHEMBL2372310 Mu-type opioid receptor Cavia cutleri 640 ChEMBL 10.1021/jm00027a018 10.7270/Q2TX3G09 8289188 Bartosz-Bechowski, H; Davis, P; Zalewska, T; Slaninova, J; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043723 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043723&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10328336 103975107 CHEMBL2372310 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062854 CC1(C)SSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H]1NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O InChI=1S/C37H44N6O8S2/c1-37(2)31(43-32(46)26(38)17-24-13-15-25(44)16-14-24)35(49)39-20-30(45)40-27(18-22-9-5-3-6-10-22)33(47)42-29(21-52-53-37)34(48)41-28(36(50)51)19-23-11-7-4-8-12-23/h3-16,26-29,31,44H,17-21,38H2,1-2H3,(H,39,49)(H,40,45)(H,41,48)(H,42,47)(H,43,46)(H,50,51)/t26-,27-,28-,29-,31-/m0/s1 SNEMTHOGAFLXTE-OLAIZJASSA-N 50043724 (S)-2-({(4R,7S)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-14,14-dimethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carbonyl}-amino)-3-phenyl-propionic acid::CHEMBL339320 Mu-type opioid receptor Cavia cutleri 83 ChEMBL 10.1021/jm00027a018 10.7270/Q2TX3G09 8289188 Bartosz-Bechowski, H; Davis, P; Zalewska, T; Slaninova, J; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043724 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043724&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10033099 103975108 CHEMBL339320 ZINC95609570 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50062855 CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23-,24-/m0/s1 MCMMCRYPQBNCPH-DVKRWUGUSA-N 50001683 13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid::7-Benzyl-10-{[3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL294616::DPDPE Mu-type opioid receptor Cavia cutleri 7300 ChEMBL 10.1021/jm00027a018 10.7270/Q2TX3G09 8289188 Bartosz-Bechowski, H; Davis, P; Zalewska, T; Slaninova, J; Porreca, F; Yamamura, HI; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001683&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299404 103916113 CHEMBL294616 ZINC27520031 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50064982 C(C1CCC1)N1CC[C@]23CCCC[C@H]2[C@H]1Cc1ccc(cc31)-c1nnn[nH]1 InChI=1S/C22H29N5/c1-2-9-22-10-11-27(14-15-4-3-5-15)20(18(22)6-1)13-16-7-8-17(12-19(16)22)21-23-25-26-24-21/h7-8,12,15,18,20H,1-6,9-11,13-14H2,(H,23,24,25,26)/t18-,20+,22+/m0/s1 JCEYFGFSKVUFMR-CZTZKLFOSA-N 50138018 3-(1'H-Tetrazol-5'-yl)-N-cyclobutylmethylmorphinan::CHEMBL296328 Mu-type opioid receptor Cavia cutleri 1100 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50138018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50138018&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11302996 104028156 CHEMBL296328 ZINC13532332 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50064983 Oc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC#C)c2c1 InChI=1S/C19H21NO2/c1-2-10-20-11-9-19-8-4-3-5-15(19)17(20)18(22)14-7-6-13(21)12-16(14)19/h1,6-7,12,15,17,21H,3-5,8-11H2/t15-,17-,19+/m0/s1 NJPFJWKMEKVNOA-VDZJLULYSA-N 50138003 3-Hydroxy-10-keto-N-propargylmorphinan::CHEMBL298571 Mu-type opioid receptor Cavia cutleri 190 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50138003 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50138003&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11335412 104028141 CHEMBL298571 ZINC13532269 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50064985 O=C1[C@@H]2[C@@H]3CCCC[C@]3(CCN2CC#C)c2cc(OCC#C)ccc12 InChI=1S/C22H23NO2/c1-3-12-23-13-11-22-10-6-5-7-18(22)20(23)21(24)17-9-8-16(15-19(17)22)25-14-4-2/h1-2,8-9,15,18,20H,5-7,10-14H2/t18-,20-,22+/m0/s1 NDIDPWPAWPAYHT-RCZSKKKRSA-N 50137991 3-O-Propargyl-10-keto-N-propargylmorphinan::CHEMBL300023 Mu-type opioid receptor Cavia cutleri 710 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137991 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137991&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11163411 104028129 CHEMBL300023 ZINC13532259 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50064989 COc1ccc2C(=O)[C@H]3NCC[C@@]4(CCCC[C@@H]34)c2c1 InChI=1S/C17H21NO2/c1-20-11-5-6-12-14(10-11)17-7-3-2-4-13(17)15(16(12)19)18-9-8-17/h5-6,10,13,15,18H,2-4,7-9H2,1H3/t13-,15-,17+/m0/s1 HPLRGHPULWMCLT-JLJPHGGASA-N 50138012 3-Methoxy normorphinan::CHEMBL297467 Mu-type opioid receptor Cavia cutleri 110 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50138012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50138012&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10635842 104028150 CHEMBL297467 ZINC13532255 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50064990 Oc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3CCF)c2c1 InChI=1S/C18H22FNO2/c19-8-10-20-9-7-18-6-2-1-3-14(18)16(20)17(22)13-5-4-12(21)11-15(13)18/h4-5,11,14,16,21H,1-3,6-10H2/t14-,16-,18+/m0/s1 BXMPBRCWWSWXFY-QILLFSRXSA-N 50138015 3-Hydroxy-10-keto-N-(2-fluoroethyl)morphinan::CHEMBL48816 Mu-type opioid receptor Cavia cutleri 560 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50138015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50138015&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11449538 104028153 CHEMBL48816 ZINC13532282 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50064991 O=C1[C@@H]2[C@@H]3CCCC[C@]3(CCN2CC2CCC2)c2cc(OCC3CCC3)ccc12 InChI=1S/C26H35NO2/c28-25-21-11-10-20(29-17-19-7-4-8-19)15-23(21)26-12-2-1-9-22(26)24(25)27(14-13-26)16-18-5-3-6-18/h10-11,15,18-19,22,24H,1-9,12-14,16-17H2/t22-,24-,26+/m0/s1 CNPKHMRIMIVLGC-LLZJGCNPSA-N 50137995 3-O-Cyclobutylmethyl-10-keto-N-cyclobutylmethylmorphinan::CHEMBL298446 Mu-type opioid receptor Cavia cutleri 800 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137995 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137995&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11153600 104028133 CHEMBL298446 ZINC13532260 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50064992 Oc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3CCCF)c2c1 InChI=1S/C19H24FNO2/c20-9-3-10-21-11-8-19-7-2-1-4-15(19)17(21)18(23)14-6-5-13(22)12-16(14)19/h5-6,12,15,17,22H,1-4,7-11H2/t15-,17-,19+/m0/s1 LDUCOIQQNZJWTI-VDZJLULYSA-N 50137986 3-Hydroxy-10-keto-N-(3-fluoropropyl)morphinan::CHEMBL295237 Mu-type opioid receptor Cavia cutleri 20 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137986 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137986&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11404339 104028124 CHEMBL295237 ZINC13532279 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50064994 CC(C)=CCN1CC[C@]23CCCC[C@H]2[C@H]1C(=O)c1ccc(O)cc31 InChI=1S/C21H27NO2/c1-14(2)8-11-22-12-10-21-9-4-3-5-17(21)19(22)20(24)16-7-6-15(23)13-18(16)21/h6-8,13,17,19,23H,3-5,9-12H2,1-2H3/t17-,19-,21+/m0/s1 PBAUESPYKMKWLB-HFSMHLIXSA-N 50138002 3-Hydroxy-10-keto-N-(3,3-dimethylallyl)morphinan::CHEMBL295402 Mu-type opioid receptor Cavia cutleri 19 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50138002 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50138002&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11416117 104028140 CHEMBL295402 ZINC13532276 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50064995 Nc1ccc2C[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CCC3)c2c1 InChI=1S/C21H30N2/c22-17-8-7-16-12-20-18-6-1-2-9-21(18,19(16)13-17)10-11-23(20)14-15-4-3-5-15/h7-8,13,15,18,20H,1-6,9-12,14,22H2/t18-,20+,21+/m0/s1 HXKMQQLYEGWJQB-CEWLAPEOSA-N 50138014 3-Amino-N-cyclobutylmethylmorphinan::3-aminobutorphan::CHEMBL49143::MCL-182 Mu-type opioid receptor Cavia cutleri 3.7 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50138014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50138014&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11255361 104028152 CHEMBL49143 ZINC13532326 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50064996 CN1CC[C@]23CCCC[C@H]2[C@H]1Cc1ccc(cc31)-c1nnn[nH]1 InChI=1S/C18H23N5/c1-23-9-8-18-7-3-2-4-14(18)16(23)11-12-5-6-13(10-15(12)18)17-19-21-22-20-17/h5-6,10,14,16H,2-4,7-9,11H2,1H3,(H,19,20,21,22)/t14-,16+,18+/m0/s1 PWTXBXKXSKQFAM-YXJHDRRASA-N 50137993 3-(1'H-Tetrazol-5'-yl)-N-methylmorphinan::CHEMBL299132 Mu-type opioid receptor Cavia cutleri 380 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137993&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11266864 104028131 CHEMBL299132 ZINC13532329 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50064997 O=C1[C@@H]2[C@@H]3CCCC[C@]3(CCN2CC2CCC2)c2cc(ccc12)C#N InChI=1S/C22H26N2O/c23-13-16-7-8-17-19(12-16)22-9-2-1-6-18(22)20(21(17)25)24(11-10-22)14-15-4-3-5-15/h7-8,12,15,18,20H,1-6,9-11,14H2/t18-,20-,22+/m0/s1 UNHCJFJJYXMVDS-RCZSKKKRSA-N 50138017 3-Cyano-10-keto-N-cyclobutylmethylmorphinan::CHEMBL46320 Mu-type opioid receptor Cavia cutleri 2200 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50138017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50138017&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11175032 104028155 CHEMBL46320 ZINC13532294 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50064998 CN1CC[C@]23CCCC[C@H]2[C@H]1C(=O)c1ccc(O)cc31 InChI=1S/C17H21NO2/c1-18-9-8-17-7-3-2-4-13(17)15(18)16(20)12-6-5-11(19)10-14(12)17/h5-6,10,13,15,19H,2-4,7-9H2,1H3/t13-,15-,17+/m0/s1 LDVDMWWWDMAYJS-JLJPHGGASA-N 50137988 3-Hydroxy-10-keto-N-methylmorphinan::CHEMBL432120 Mu-type opioid receptor Cavia cutleri 21 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137988 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137988&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11149937 104028126 CHEMBL432120 ZINC13532253 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50065003 NC(=O)c1ccc2C[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CC3)c2c1 InChI=1S/C21H28N2O/c22-20(24)16-7-6-15-12-19-17-3-1-2-8-21(17,18(15)11-16)9-10-23(19)13-14-4-5-14/h6-7,11,14,17,19H,1-5,8-10,12-13H2,(H2,22,24)/t17-,19+,21+/m0/s1 YFSMHTBENRCTNZ-FBBABVLZSA-N 50137996 3-Carboxamido-N-cyclopropylmethylmorphinan::CHEMBL300033 Mu-type opioid receptor Cavia cutleri 0.06 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137996&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11404566 104028134 CHEMBL300033 ZINC13532344 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50065010 NCc1ccc2C[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CCC3)c2c1 InChI=1S/C22H32N2/c23-14-17-7-8-18-13-21-19-6-1-2-9-22(19,20(18)12-17)10-11-24(21)15-16-4-3-5-16/h7-8,12,16,19,21H,1-6,9-11,13-15,23H2/t19-,21+,22+/m0/s1 FUSBCWRQOIJHOW-KSEOMHKRSA-N 50138016 3-Aminomethyl-N-cyclobutylmethylmorphinan::CHEMBL298688 Mu-type opioid receptor Cavia cutleri 8.5 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50138016 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50138016&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11359253 104028154 CHEMBL298688 ZINC13532338 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50065011 O=C1[C@@H]2[C@@H]3CCCC[C@]3(CCN2CC2CCC2)c2cc(ccc12)-c1nnn[nH]1 InChI=1S/C22H27N5O/c28-20-16-8-7-15(21-23-25-26-24-21)12-18(16)22-9-2-1-6-17(22)19(20)27(11-10-22)13-14-4-3-5-14/h7-8,12,14,17,19H,1-6,9-11,13H2,(H,23,24,25,26)/t17-,19-,22+/m0/s1 QULFSXXDFAAEIP-LQBOVUBWSA-N 50137987 3-Tetrazolo-10-keto-N-cyclobutylmethylmorphinan::CHEMBL48974 Mu-type opioid receptor Cavia cutleri 230 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137987 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137987&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11268925 104028125 CHEMBL48974 ZINC13532310 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50065012 CN1CC[C@]23CCCC[C@H]2[C@H]1Cc1ccc(cc31)C(N)=O InChI=1S/C18H24N2O/c1-20-9-8-18-7-3-2-4-14(18)16(20)11-12-5-6-13(17(19)21)10-15(12)18/h5-6,10,14,16H,2-4,7-9,11H2,1H3,(H2,19,21)/t14-,16+,18+/m0/s1 KTMWGCFRTKWYQF-YXJHDRRASA-N 50138007 3-Carboxamido-N-methylmorphinan::CHEMBL297292 Mu-type opioid receptor Cavia cutleri 0.07 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50138007 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50138007&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11150306 104028145 CHEMBL297292 ZINC13532341 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50065017 Nc1ccc2C[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CC3)c2c1 InChI=1S/C20H28N2/c21-16-7-6-15-11-19-17-3-1-2-8-20(17,18(15)12-16)9-10-22(19)13-14-4-5-14/h6-7,12,14,17,19H,1-5,8-11,13,21H2/t17-,19+,20+/m0/s1 JUWFFFGTHLQORF-DFQSSKMNSA-N 50137997 3-Amino-N-cyclopropylmethylmorphinan::3-aminocyclorphan::CHEMBL299220::MCL-149 Mu-type opioid receptor Cavia cutleri 1.3 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137997 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137997&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11392313 104028135 CHEMBL299220 ZINC13532322 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50065018 CC[C@]12CCN(CC3CC3)C([C@@H]1C)C(=O)c1ccc(O)cc21 InChI=1S/C19H25NO2/c1-3-19-8-9-20(11-13-4-5-13)17(12(19)2)18(22)15-7-6-14(21)10-16(15)19/h6-7,10,12-13,17,21H,3-5,8-9,11H2,1-2H3/t12-,17?,19-/m0/s1 SEJUQQOPVAUETF-BKBNBNODSA-N 50000091 (6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::(6S,11R)-3-Cyclopropylmethyl-9-hydroxy-6,11-dimethyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one (ethylketocyclazocine)::3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one(Ethylketazocine, EKC)::CHEMBL279968::EKC::EKC(-) Mu-type opioid receptor Cavia cutleri 0.78 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000091&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44273397 103914788 CHEMBL279968 ZINC00967957 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50065020 Oc1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CC3)c2c1 InChI=1S/C20H25NO2/c22-14-6-7-15-17(11-14)20-8-2-1-3-16(20)18(19(15)23)21(10-9-20)12-13-4-5-13/h6-7,11,13,16,18,22H,1-5,8-10,12H2/t16-,18-,20+/m0/s1 GBFZDUXAYHZNHA-XKGZKEIXSA-N 50138004 3-Hydroxy-10-keto-N-cyclopropylmethylmorphinan::CHEMBL298027 Mu-type opioid receptor Cavia cutleri 240 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50138004 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50138004&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10805007 104028142 CHEMBL298027 ZINC13532263 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50065023 CN1CC[C@]23CCCC[C@H]2[C@H]1Cc1ccc(O)cc31 InChI=1S/C17H23NO/c1-18-9-8-17-7-3-2-4-14(17)16(18)10-12-5-6-13(19)11-15(12)17/h5-6,11,14,16,19H,2-4,7-10H2,1H3/t14-,16+,17+/m0/s1 JAQUASYNZVUNQP-USXIJHARSA-N 50017233 CHEMBL592::LEVO-DROMORAN::LEVORPHANOL Mu-type opioid receptor Cavia cutleri 0.21 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017233 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017233&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5359272 103928501 CHEMBL592 DB00854 C08014 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50065024 Oc1ccc2C[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CCC3)c2c1 InChI=1S/C21H29NO/c23-17-8-7-16-12-20-18-6-1-2-9-21(18,19(16)13-17)10-11-22(20)14-15-4-3-5-15/h7-8,13,15,18,20,23H,1-6,9-12,14H2/t18-,20+,21+/m0/s1 YSTAPDGDOHWKQR-CEWLAPEOSA-N 50135808 (-)-3-Hydroxy-N-cyclobutylmethylmorphinan S(+)-Mandelate::17-cyclobutylmethyl-(1R,9R,10R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol::3-Hydroxy-N-cyclobutylmethylmorphinan::BUTORPHAN::CHEMBL301160::MCL-101 Mu-type opioid receptor Cavia cutleri 0.23 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50135808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50135808&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9804450 104026158 CHEMBL301160 ZINC03982790 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50065026 OC(=O)c1ccc2C(=O)[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CCC3)c2c1 InChI=1S/C22H27NO3/c24-20-16-8-7-15(21(25)26)12-18(16)22-9-2-1-6-17(22)19(20)23(11-10-22)13-14-4-3-5-14/h7-8,12,14,17,19H,1-6,9-11,13H2,(H,25,26)/t17-,19-,22+/m0/s1 DKIHSWCVZDLLIX-LQBOVUBWSA-N 50138005 3-Carboxyl-10-keto-N-cyclobutylmethyl morphinan::CHEMBL299189 Mu-type opioid receptor Cavia cutleri 28 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50138005 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50138005&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11451042 104028143 CHEMBL299189 ZINC13532297 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50065029 Oc1ccc2C[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CC3)c2c1 InChI=1S/C20H27NO/c22-16-7-6-15-11-19-17-3-1-2-8-20(17,18(15)12-16)9-10-21(19)13-14-4-5-14/h6-7,12,14,17,19,22H,1-5,8-11,13H2/t17-,19+,20+/m0/s1 NLBUEDSBXVNAPB-DFQSSKMNSA-N 50135800 (-)-3-Hydroxy-N-cycloproypylmethylmorphinan Mandelate::17-cyclopropylmethyl-(1R,9R,10R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol::3-Hydroxy-N-cyclopropylmethylmorphinan::CHEMBL49269::CYCLORPHAN::US10231963, Table B.6::US10736890, Compound TABLE B.6::US11534436, Compound Table B.6::US9656961, Example 00123 Mu-type opioid receptor Cavia cutleri 0.06 ChEMBL 10.1021/jm0304156 10.7270/Q2KD1XB2 14695830 Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50135800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50135800&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5359966 104026150 CHEMBL49269 ZINC04215487 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50070089 CC(C)[C@H](NC(=O)[C@H]1NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SSC1(C)C)C(=O)NCC(N)=O InChI=1S/C40H56N8O10S2/c1-21(2)30(36(56)43-20-28(42)50)46-38(58)32-40(5,6)60-59-39(3,4)31(47-33(53)25(41)18-23-12-14-24(49)15-13-23)37(57)45-27(19-22-10-8-7-9-11-22)35(55)44-26(34(54)48-32)16-17-29(51)52/h7-15,21,25-27,30-32,49H,16-20,41H2,1-6H3,(H2,42,50)(H,43,56)(H,44,55)(H,45,57)(H,46,58)(H,47,53)(H,48,54)(H,51,52)/t25-,26-,27-,30-,31-,32+/m0/s1 JHEHTMMTILCKIS-PLIIALOTSA-N 50043713 3-{(4R,10R,13S)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-10-benzyl-4-[(R)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradec-7-yl}-propionic acid::CHEMBL2372208 Mu-type opioid receptor Cavia cutleri 2.24 ChEMBL 10.1021/jm00027a017 10.7270/Q2F47N7P 8289187 Misicka, A; Lipkowski, AW; Horvath, R; Davis, P; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043713 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043713&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9988211 103975097 CHEMBL2372208 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50070093 CCCC[C@H](NC(=O)[C@H]1NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SSC1(C)C)C(=O)NCC(N)=O InChI=1S/C40H56N8O10S2/c1-6-7-13-26(34(54)43-21-29(42)50)44-37(57)32-40(4,5)60-59-39(2,3)31(47-33(53)25(41)18-23-14-16-24(49)17-15-23)38(58)46-27(19-22-11-9-8-10-12-22)35(55)45-28(20-30(51)52)36(56)48-32/h8-12,14-17,25-28,31-32,49H,6-7,13,18-21,41H2,1-5H3,(H2,42,50)(H,43,54)(H,44,57)(H,45,55)(H,46,58)(H,47,53)(H,48,56)(H,51,52)/t25-,26-,27-,28-,31-,32+/m0/s1 FSUPVCRTIDVFRM-SGBLTFEXSA-N 50043716 CHEMBL2372212::{(4R,10R,13S)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-10-benzyl-4-[1-(carbamoylmethyl-carbamoyl)-pentylcarbamoyl]-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradec-7-yl}-acetic acid Mu-type opioid receptor Cavia cutleri 4.83 ChEMBL 10.1021/jm00027a017 10.7270/Q2F47N7P 8289187 Misicka, A; Lipkowski, AW; Horvath, R; Davis, P; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043716 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043716&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10328280 103975100 CHEMBL2372212 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50070095 CC(C)[C@@H](NC(=O)[C@H]1CSSC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](CC(O)=O)C(=O)N1)C(=O)NCC(N)=O InChI=1S/C35H46N8O10S2/c1-18(2)29(35(53)38-15-27(37)45)43-34(52)26-17-55-54-16-25(41-30(48)22(36)12-20-8-10-21(44)11-9-20)33(51)39-23(13-19-6-4-3-5-7-19)31(49)40-24(14-28(46)47)32(50)42-26/h3-11,18,22-26,29,44H,12-17,36H2,1-2H3,(H2,37,45)(H,38,53)(H,39,51)(H,40,49)(H,41,48)(H,42,50)(H,43,52)(H,46,47)/t22-,23-,24+,25-,26+,29+/m0/s1 YOZBAOXLTILTGR-SLTQQXTHSA-N 50043717 CHEMBL289006::{(4S,7R,10S,13R)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-10-benzyl-4-[(R)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradec-7-yl}-acetic acid Mu-type opioid receptor Cavia cutleri 2.98 ChEMBL 10.1021/jm00027a017 10.7270/Q2F47N7P 8289187 Misicka, A; Lipkowski, AW; Horvath, R; Davis, P; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043717 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043717&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44281679 103975101 CHEMBL289006 ZINC95608796 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50070096 CC(C)[C@@H](NC(=O)[C@@H]1NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CSSC1(C)C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(N)=O InChI=1S/C37H50N8O10S2/c1-19(2)29(35(54)40-17-27(39)47)44-36(55)30-37(3,4)57-56-18-26(43-31(50)23(38)14-21-10-12-22(46)13-11-21)34(53)41-24(15-20-8-6-5-7-9-20)32(51)42-25(16-28(48)49)33(52)45-30/h5-13,19,23-26,29-30,46H,14-18,38H2,1-4H3,(H2,39,47)(H,40,54)(H,41,53)(H,42,51)(H,43,50)(H,44,55)(H,45,52)(H,48,49)/t23-,24-,25+,26-,29+,30-/m0/s1 DIXNNWRHERAZLO-XYHHVMNMSA-N 50043712 CHEMBL286629::{(4S,7R,10S,13R)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-10-benzyl-4-[(R)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-3,3-dimethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradec-7-yl}-acetic acid Mu-type opioid receptor Cavia cutleri 1100 ChEMBL 10.1021/jm00027a017 10.7270/Q2F47N7P 8289187 Misicka, A; Lipkowski, AW; Horvath, R; Davis, P; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043712 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043712&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44281356 103975096 CHEMBL286629 ZINC95608810 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50070103 CCCC[C@H](NC(=O)[C@H]1NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SSC1(C)C)C(=O)N[C@@H](CC(O)=O)C(N)=O InChI=1S/C44H60N10O10S2/c1-6-7-13-29(38(60)50-30(36(46)58)21-33(56)57)49-41(63)35-44(4,5)66-65-43(2,3)34(53-37(59)28(45)18-25-14-16-27(55)17-15-25)42(64)52-31(19-24-11-9-8-10-12-24)39(61)51-32(40(62)54-35)20-26-22-47-23-48-26/h8-12,14-17,22-23,28-32,34-35,55H,6-7,13,18-21,45H2,1-5H3,(H2,46,58)(H,47,48)(H,49,63)(H,50,60)(H,51,61)(H,52,64)(H,53,59)(H,54,62)(H,56,57)/t28-,29-,30-,31-,32-,34-,35+/m0/s1 PWZZAHNMTFDCLS-YCISHLJPSA-N 50043719 3-(2-{[(4R,10R,13S)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-10-benzyl-7-(3H-imidazol-4-ylmethyl)-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carbonyl]-amino}-hexanoylamino)-succinamic acid::CHEMBL2372214 Mu-type opioid receptor Cavia cutleri 3.40 ChEMBL 10.1021/jm00027a017 10.7270/Q2F47N7P 8289187 Misicka, A; Lipkowski, AW; Horvath, R; Davis, P; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043719 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043719&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10328532 103975103 CHEMBL2372214 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50070108 CCCC[C@H](NC(=O)[C@H]1NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SSC1(C)C)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C44H59N9O11S2/c1-6-7-13-29(37(58)51-32(42(63)64)21-33(55)56)48-40(61)35-44(4,5)66-65-43(2,3)34(52-36(57)28(45)18-25-14-16-27(54)17-15-25)41(62)50-30(19-24-11-9-8-10-12-24)38(59)49-31(39(60)53-35)20-26-22-46-23-47-26/h8-12,14-17,22-23,28-32,34-35,54H,6-7,13,18-21,45H2,1-5H3,(H,46,47)(H,48,61)(H,49,59)(H,50,62)(H,51,58)(H,52,57)(H,53,60)(H,55,56)(H,63,64)/t28-,29-,30-,31-,32-,34-,35+/m0/s1 PWFTWKGPVXCOLC-YCISHLJPSA-N 50043711 2-(2-{[(4R,10R,13S)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-10-benzyl-7-(3H-imidazol-4-ylmethyl)-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carbonyl]-amino}-hexanoylamino)-succinic acid::CHEMBL2372209 Mu-type opioid receptor Cavia cutleri 4500 ChEMBL 10.1021/jm00027a017 10.7270/Q2F47N7P 8289187 Misicka, A; Lipkowski, AW; Horvath, R; Davis, P; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043711 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043711&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10463591 103975095 CHEMBL2372209 C02715 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50070110 CC(C)[C@H](NC(=O)[C@H]1NC(=O)[C@H](CO)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SSC1(C)C)C(=O)NCC(N)=O InChI=1S/C38H54N8O9S2/c1-20(2)28(34(53)41-18-27(40)49)44-36(55)30-38(5,6)57-56-37(3,4)29(45-31(50)24(39)16-22-12-14-23(48)15-13-22)35(54)42-25(17-21-10-8-7-9-11-21)32(51)43-26(19-47)33(52)46-30/h7-15,20,24-26,28-30,47-48H,16-19,39H2,1-6H3,(H2,40,49)(H,41,53)(H,42,54)(H,43,51)(H,44,55)(H,45,50)(H,46,52)/t24-,25-,26-,28-,29-,30+/m0/s1 IYZWTOVPKFCKCW-CUKNGYHYSA-N 50043718 (4R,10R,13S)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-10-benzyl-7-hydroxymethyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid [(R)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propyl]-amide::CHEMBL2372213 Mu-type opioid receptor Cavia cutleri 3300 ChEMBL 10.1021/jm00027a017 10.7270/Q2F47N7P 8289187 Misicka, A; Lipkowski, AW; Horvath, R; Davis, P; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043718 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043718&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11766007 103975102 CHEMBL2372213 ZINC95608764 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50070117 CC(C)[C@@H](NC(=O)[C@@H]1NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SSC1(C)C)C(=O)NCC(N)=O InChI=1S/C39H54N8O10S2/c1-20(2)29(35(55)42-19-27(41)49)45-37(57)31-39(5,6)59-58-38(3,4)30(46-32(52)24(40)16-22-12-14-23(48)15-13-22)36(56)44-25(17-21-10-8-7-9-11-21)33(53)43-26(18-28(50)51)34(54)47-31/h7-15,20,24-26,29-31,48H,16-19,40H2,1-6H3,(H2,41,49)(H,42,55)(H,43,53)(H,44,56)(H,45,57)(H,46,52)(H,47,54)(H,50,51)/t24-,25-,26+,29+,30+,31-/m0/s1 CIXRLSHQKQIGJK-NTWBUTRESA-N 50043714 CHEMBL288317::{(4S,7R,10S,13R)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-10-benzyl-4-[(R)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradec-7-yl}-acetic acid Mu-type opioid receptor Cavia cutleri 68000 ChEMBL 10.1021/jm00027a017 10.7270/Q2F47N7P 8289187 Misicka, A; Lipkowski, AW; Horvath, R; Davis, P; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043714 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043714&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44281314 103975098 CHEMBL288317 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50070121 CSCC[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(N)=O InChI=1S/C44H62N10O10S2/c1-25(2)18-34(42(62)50-32(15-17-66-4)40(60)51-33(38(46)58)22-37(56)57)52-44(64)36(21-28-23-47-24-48-28)54-43(63)35(20-26-8-6-5-7-9-26)53-41(61)31(14-16-65-3)49-39(59)30(45)19-27-10-12-29(55)13-11-27/h5-13,23-25,30-36,55H,14-22,45H2,1-4H3,(H2,46,58)(H,47,48)(H,49,59)(H,50,62)(H,51,60)(H,52,64)(H,53,61)(H,54,63)(H,56,57)/t30-,31-,32-,33-,34-,35-,36-/m0/s1 BHSURCCZOBVHJJ-QJCLFNHPSA-N 50009180 3-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyrylamino}-3-phenyl-propionylamino)-3-(1H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-4-methylsulfanyl-butyrylamino)-succinamic acid::3-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyrylamino}-3-phenyl-propionylamino)-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-4-methylsulfanyl-butyrylamino)-succinamic acid::CHEMBL32202::Tyr-D-Met-Phe-His-Leu-Met-Asp-NH2 Mu-type opioid receptor Cavia cutleri 3400 ChEMBL 10.1021/jm00027a017 10.7270/Q2F47N7P 8289187 Misicka, A; Lipkowski, AW; Horvath, R; Davis, P; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009180 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009180&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14504437 103922237 CHEMBL32202 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50070128 CC(C)[C@@H](NC(=O)[C@H]1NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SSC1(C)C)C(=O)NCC(N)=O InChI=1S/C39H54N8O10S2/c1-20(2)29(35(55)42-19-27(41)49)45-37(57)31-39(5,6)59-58-38(3,4)30(46-32(52)24(40)16-22-12-14-23(48)15-13-22)36(56)44-25(17-21-10-8-7-9-11-21)33(53)43-26(18-28(50)51)34(54)47-31/h7-15,20,24-26,29-31,48H,16-19,40H2,1-6H3,(H2,41,49)(H,42,55)(H,43,53)(H,44,56)(H,45,57)(H,46,52)(H,47,54)(H,50,51)/t24-,25-,26+,29+,30+,31+/m0/s1 CIXRLSHQKQIGJK-JITDTWSESA-N 50043715 CHEMBL284621::{(4R,7R,10S,13R)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-10-benzyl-4-[(R)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradec-7-yl}-acetic acid Mu-type opioid receptor Cavia cutleri 5500 ChEMBL 10.1021/jm00027a017 10.7270/Q2F47N7P 8289187 Misicka, A; Lipkowski, AW; Horvath, R; Davis, P; Yamamura, HI; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043715 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043715&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44281742 103975099 CHEMBL284621 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50076808 COc1cccc(c1)[C@H](N1C[C@@H](C)N(Cc2ccccc2)C[C@@H]1C)c1ccc2CN(CCC(O)=O)Cc2c1 InChI=1S/C32H39N3O3/c1-23-19-35(24(2)18-34(23)20-25-8-5-4-6-9-25)32(26-10-7-11-30(17-26)38-3)27-12-13-28-21-33(15-14-31(36)37)22-29(28)16-27/h4-13,16-17,23-24,32H,14-15,18-22H2,1-3H3,(H,36,37)/t23-,24+,32+/m1/s1 JBRMBTUADMJWQH-FXZPAHAQSA-N 50422812 CHEMBL382283 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1016/j.bmcl.2005.10.102 10.7270/Q2930VG2 16290934 Middleton, DS; Maw, GN; Challenger, C; Jessiman, A; Johnson, PS; Million, WA; Nichols, CL; Price, JA; Trevethick, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422812 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422812&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44407693 164151687 CHEMBL382283 ZINC28568899 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50076861 CCN(CC)C(=O)c1ccc(cc1)[C@@H](N1C[C@@H](C)N(CC=C)C[C@@H]1C)c1cccc(OC)c1 InChI=1S/C28H39N3O2/c1-7-17-30-19-22(5)31(20-21(30)4)27(25-11-10-12-26(18-25)33-6)23-13-15-24(16-14-23)28(32)29(8-2)9-3/h7,10-16,18,21-22,27H,1,8-9,17,19-20H2,2-6H3/t21-,22+,27-/m1/s1 KQWVAUSXZDRQPZ-UMTXDNHDSA-N 50039029 (+)-4-((alpha R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-methoxyphenyl)methyl)-N,N-diethylbenzamide::(+)-4-[(alpha-R)-alpha-[2S,5R]-4-allyl[2,5-dimethyl-1-piperazinyl]-3-methoxybenzyl]-N,N-diethylbenzamide::3-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(4-diethylcarbamoyl-phenyl)-methyl]-benzoic acid::4-((R)-((2R,5S)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-methoxyphenyl)methyl)-N,N-diethylbenzamide::4-((R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-methoxyphenyl)methyl)-N,N-diethylbenzamide::4-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide (SNC 80)::4-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide(SNC-80)::4-[(R)-((2R,5S)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-((R)-4-(S)-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-[(2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl](3-methoxyphenyl)-methyl]-N,N-diethylbenzamide::CHEMBL13470::SNC-80 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1016/j.bmcl.2005.10.102 10.7270/Q2930VG2 16290934 Middleton, DS; Maw, GN; Challenger, C; Jessiman, A; Johnson, PS; Million, WA; Nichols, CL; Price, JA; Trevethick, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039029&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 123924 103946292 CHEMBL13470 1611 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50076865 COc1cccc(c1)[C@H](N1C[C@@H](C)N(Cc2ccccc2)C[C@@H]1C)c1ccc2CCN(CCC(O)=O)Cc2c1 InChI=1S/C33H41N3O3/c1-24-21-36(25(2)20-35(24)22-26-8-5-4-6-9-26)33(28-10-7-11-31(19-28)39-3)29-13-12-27-14-16-34(17-15-32(37)38)23-30(27)18-29/h4-13,18-19,24-25,33H,14-17,20-23H2,1-3H3,(H,37,38)/t24-,25+,33+/m1/s1 XLNBMFNKGUOEFO-SQJKUQPUSA-N 50422797 CHEMBL380749 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1016/j.bmcl.2005.10.102 10.7270/Q2930VG2 16290934 Middleton, DS; Maw, GN; Challenger, C; Jessiman, A; Johnson, PS; Million, WA; Nichols, CL; Price, JA; Trevethick, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422797&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44407706 164151672 CHEMBL380749 ZINC28569102 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015491 CN[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)NCC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(C)[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(N)=O InChI=1S/C48H77N15O9/c1-28(2)22-34(41(49)67)61-45(71)38(15-11-21-56-48(52)53)63(6)46(72)33(14-10-20-55-47(50)51)60-43(69)36(23-29(3)4)62-44(70)37(25-30-12-8-7-9-13-30)59-40(66)27-57-39(65)26-58-42(68)35(54-5)24-31-16-18-32(64)19-17-31/h7-9,12-13,16-19,28-29,33-38,54,64H,10-11,14-15,20-27H2,1-6H3,(H2,49,67)(H,57,65)(H,58,68)(H,59,66)(H,60,69)(H,61,71)(H,62,70)(H4,50,51,55)(H4,52,53,56)/t33-,34-,35-,36-,37+,38-/m0/s1 ZXAIDFHVAANNKH-WRQFUQGOSA-N 50010535 2-{5-Guanidino-2-[(5-guanidino-2-{2-[2-(2-{2-[3-(4-hydroxy-phenyl)-2-methylamino-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-pentanoyl)-methyl-amino]-pentanoylamino}-4-methyl-pentanoic acid amide::CHEMBL266035 Mu-type opioid receptor Cavia cutleri 3.3 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010535 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010535&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44307318 103923311 CHEMBL266035 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015506 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O InChI=1S/C46H73N15O9/c1-5-27(4)38(39(48)65)61-42(68)33(14-10-20-54-46(51)52)58-41(67)32(13-9-19-53-45(49)50)59-43(69)34(21-26(2)3)60-44(70)35(23-28-11-7-6-8-12-28)57-37(64)25-55-36(63)24-56-40(66)31(47)22-29-15-17-30(62)18-16-29/h6-8,11-12,15-18,26-27,31-35,38,62H,5,9-10,13-14,19-25,47H2,1-4H3,(H2,48,65)(H,55,63)(H,56,66)(H,57,64)(H,58,67)(H,59,69)(H,60,70)(H,61,68)(H4,49,50,53)(H4,51,52,54)/t27-,31-,32-,33-,34-,35+,38-/m0/s1 ALYDWGRDFMLDRH-VORHEVMJSA-N 50010538 2-[2-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-5-guanidino-pentanoylamino)-5-guanidino-pentanoylamino]-3-methyl-pentanoic acid amide::CHEMBL437242 Mu-type opioid receptor Cavia cutleri 7.2 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010538 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010538&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44307234 103923314 CHEMBL437242 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015513 CN[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)NCC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(N)=O InChI=1S/C47H75N15O9/c1-27(2)21-34(40(48)66)61-43(69)33(14-10-20-55-47(51)52)59-42(68)32(13-9-19-54-46(49)50)60-44(70)36(22-28(3)4)62-45(71)37(24-29-11-7-6-8-12-29)58-39(65)26-56-38(64)25-57-41(67)35(53-5)23-30-15-17-31(63)18-16-30/h6-8,11-12,15-18,27-28,32-37,53,63H,9-10,13-14,19-26H2,1-5H3,(H2,48,66)(H,56,64)(H,57,67)(H,58,65)(H,59,68)(H,60,70)(H,61,69)(H,62,71)(H4,49,50,54)(H4,51,52,55)/t32-,33-,34-,35-,36-,37+/m0/s1 OBZTVKAUYYDOFM-OZBJQVERSA-N 50010536 2-[5-Guanidino-2-(5-guanidino-2-{2-[2-(2-{2-[3-(4-hydroxy-phenyl)-2-methylamino-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-pentanoylamino)-pentanoylamino]-4-methyl-pentanoic acid amide::CHEMBL263031 Mu-type opioid receptor Cavia cutleri 1.4 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010536 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010536&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44306645 103923312 CHEMBL263031 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015518 CCNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)N(C)C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H]1CSSC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N1 InChI=1S/C47H73N15O9S2/c1-5-53-40(66)33(21-27(2)3)59-44(70)37(14-10-20-55-47(51)52)62(4)45(71)32(13-9-19-54-46(49)50)58-43(69)36-26-73-72-25-35(60-39(65)31(48)22-29-15-17-30(63)18-16-29)41(67)56-24-38(64)57-34(42(68)61-36)23-28-11-7-6-8-12-28/h6-8,11-12,15-18,27,31-37,63H,5,9-10,13-14,19-26,48H2,1-4H3,(H,53,66)(H,56,67)(H,57,64)(H,58,69)(H,59,70)(H,60,65)(H,61,68)(H4,49,50,54)(H4,51,52,55)/t31-,32-,33-,34+,35-,36+,37-/m0/s1 UQHCMUXJGZRDTC-ADYVUFBVSA-N 50010532 13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid (1-{[1-(1-ethylcarbamoyl-3-methyl-butylcarbamoyl)-4-guanidino-butyl]-methyl-carbamoyl}-4-guanidino-butyl)-amide::CHEMBL441939 Mu-type opioid receptor Cavia cutleri 0.007000 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010532 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010532&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44306943 103923308 CHEMBL441939 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015523 CN[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(N)=O InChI=1S/C48H77N15O9/c1-27(2)22-35(40(49)66)62-43(69)34(15-11-21-56-48(52)53)60-42(68)33(14-10-20-55-47(50)51)61-45(71)37(23-28(3)4)63-46(72)38(25-30-12-8-7-9-13-30)59-39(65)26-57-41(67)29(5)58-44(70)36(54-6)24-31-16-18-32(64)19-17-31/h7-9,12-13,16-19,27-29,33-38,54,64H,10-11,14-15,20-26H2,1-6H3,(H2,49,66)(H,57,67)(H,58,70)(H,59,65)(H,60,68)(H,61,71)(H,62,69)(H,63,72)(H4,50,51,55)(H4,52,53,56)/t29-,33-,34-,35-,36-,37-,38-/m0/s1 LBTOPPHBIVWGRP-AVTNSMPVSA-N 50010537 2-[5-Guanidino-2-(5-guanidino-2-{2-[2-(2-{2-[3-(4-hydroxy-phenyl)-2-methylamino-propionylamino]-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-pentanoylamino)-pentanoylamino]-4-methyl-pentanoic acid amide::CHEMBL266845 Mu-type opioid receptor Cavia cutleri 14 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010537 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010537&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44307168 103923313 CHEMBL266845 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50088087 CC(C)C[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C29H39N5O7/c1-17(2)13-24(29(40)41)34-28(39)23(15-19-7-5-4-6-8-19)33-25(36)16-31-26(37)18(3)32-27(38)22(30)14-20-9-11-21(35)12-10-20/h4-12,17-18,22-24,35H,13-16,30H2,1-3H3,(H,31,37)(H,32,38)(H,33,36)(H,34,39)(H,40,41)/t18-,22+,23+,24-/m1/s1 ZHUJMSMQIPIPTF-IBURTVSXSA-N 21025 (2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanamido]-4-methylpentanoic acid::(D-Ala2,D-Leu5)-Enkephalin::BW-180C::CHEMBL340032::DADLE::DADLE-OH::H-Tyr-D-Ala-Gly-Phe-D-Leu-OH::[D-Ala2-D-Leu5]enkephalin Mu-type opioid receptor Cavia cutleri 13 ChEMBL 10.1016/j.bmc.2014.02.015 10.7270/Q29Z96DB 24613457 Cai, J; Song, B; Cai, Y; Ma, Y; Lam, AL; Magiera, J; Sekar, S; Wyse, BD; Ambo, A; Sasaki, Y; Lazarus, LH; Smith, MT; Li, T Nanjing Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21025&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 6917707 49689098 CHEMBL340032 ZINC14952092 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50088090 CC(C)C[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C29H39N5O7/c1-17(2)13-24(29(40)41)34-28(39)23(15-19-7-5-4-6-8-19)33-25(36)16-31-26(37)18(3)32-27(38)22(30)14-20-9-11-21(35)12-10-20/h4-12,17-18,22-24,35H,13-16,30H2,1-3H3,(H,31,37)(H,32,38)(H,33,36)(H,34,39)(H,40,41)/t18-,22+,23+,24-/m1/s1 ZHUJMSMQIPIPTF-IBURTVSXSA-N 21025 (2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanamido]-4-methylpentanoic acid::(D-Ala2,D-Leu5)-Enkephalin::BW-180C::CHEMBL340032::DADLE::DADLE-OH::H-Tyr-D-Ala-Gly-Phe-D-Leu-OH::[D-Ala2-D-Leu5]enkephalin Mu-type opioid receptor Cavia cutleri 3.2 ChEMBL 10.1016/j.bmc.2014.02.015 10.7270/Q29Z96DB 24613457 Cai, J; Song, B; Cai, Y; Ma, Y; Lam, AL; Magiera, J; Sekar, S; Wyse, BD; Ambo, A; Sasaki, Y; Lazarus, LH; Smith, MT; Li, T Nanjing Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21025&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 6917707 49689098 CHEMBL340032 ZINC14952092 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50087966 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O InChI=1S/C36H42N6O5/c1-21-15-25(43)16-22(2)27(21)19-28(37)36(47)42-14-8-13-32(42)35(46)41-31(17-23-9-4-3-5-10-23)34(45)40-30(33(38)44)18-24-20-39-29-12-7-6-11-26(24)29/h3-7,9-12,15-16,20,28,30-32,39,43H,8,13-14,17-19,37H2,1-2H3,(H2,38,44)(H,40,45)(H,41,46)/t28-,30-,31-,32-/m0/s1 KSVLXWHLBMOFAO-MCEBTLFFSA-N 50166065 (S)-1-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid {(S)-1-[(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-phenyl-ethyl}-amide::CHEMBL365983 Mu-type opioid receptor Cavia cutleri 207 ChEMBL 10.1016/j.bmc.2014.02.015 10.7270/Q29Z96DB 24613457 Cai, J; Song, B; Cai, Y; Ma, Y; Lam, AL; Magiera, J; Sekar, S; Wyse, BD; Ambo, A; Sasaki, Y; Lazarus, LH; Smith, MT; Li, T Nanjing Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50166065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50166065&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44400198 104051481 CHEMBL365983 ZINC28477839 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50087967 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cccc2ccccc12)C(N)=O InChI=1S/C38H43N5O5/c1-23-18-28(44)19-24(2)30(23)22-31(39)38(48)43-17-9-16-34(43)37(47)42-33(20-25-10-4-3-5-11-25)36(46)41-32(35(40)45)21-27-14-8-13-26-12-6-7-15-29(26)27/h3-8,10-15,18-19,31-34,44H,9,16-17,20-22,39H2,1-2H3,(H2,40,45)(H,41,46)(H,42,47)/t31-,32-,33-,34-/m0/s1 WSANIYPIWXGLEG-CUPIEXAXSA-N 50009251 CHEMBL3233191 Mu-type opioid receptor Cavia cutleri 14 ChEMBL 10.1016/j.bmc.2014.02.015 10.7270/Q29Z96DB 24613457 Cai, J; Song, B; Cai, Y; Ma, Y; Lam, AL; Magiera, J; Sekar, S; Wyse, BD; Ambo, A; Sasaki, Y; Lazarus, LH; Smith, MT; Li, T Nanjing Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009251 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009251&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655507 103922307 CHEMBL3233191 ZINC26394003 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50087968 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(N)=O InChI=1S/C38H43N5O5/c1-23-17-29(44)18-24(2)30(23)22-31(39)38(48)43-16-8-13-34(43)37(47)42-33(20-25-9-4-3-5-10-25)36(46)41-32(35(40)45)21-26-14-15-27-11-6-7-12-28(27)19-26/h3-7,9-12,14-15,17-19,31-34,44H,8,13,16,20-22,39H2,1-2H3,(H2,40,45)(H,41,46)(H,42,47)/t31-,32-,33-,34-/m0/s1 XQWLHPWPDQSALN-CUPIEXAXSA-N 50009254 CHEMBL3233192 Mu-type opioid receptor Cavia cutleri 40 ChEMBL 10.1016/j.bmc.2014.02.015 10.7270/Q29Z96DB 24613457 Cai, J; Song, B; Cai, Y; Ma, Y; Lam, AL; Magiera, J; Sekar, S; Wyse, BD; Ambo, A; Sasaki, Y; Lazarus, LH; Smith, MT; Li, T Nanjing Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009254&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71566771 103922310 CHEMBL3233192 ZINC38158973 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50087969 Cc1cc(C)c(C[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C(N)=O)c(C)c1 InChI=1S/C37H47N5O5/c1-21-14-22(2)29(23(3)15-21)20-31(34(39)44)40-35(45)32(18-26-10-7-6-8-11-26)41-36(46)33-12-9-13-42(33)37(47)30(38)19-28-24(4)16-27(43)17-25(28)5/h6-8,10-11,14-17,30-33,43H,9,12-13,18-20,38H2,1-5H3,(H2,39,44)(H,40,45)(H,41,46)/t30-,31-,32-,33-/m0/s1 TZXWLEXBWCBJTK-YRCZKMHPSA-N 50009264 CHEMBL3233193 Mu-type opioid receptor Cavia cutleri 67 ChEMBL 10.1016/j.bmc.2014.02.015 10.7270/Q29Z96DB 24613457 Cai, J; Song, B; Cai, Y; Ma, Y; Lam, AL; Magiera, J; Sekar, S; Wyse, BD; Ambo, A; Sasaki, Y; Lazarus, LH; Smith, MT; Li, T Nanjing Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009264 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009264&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655508 103922320 CHEMBL3233193 ZINC13823359 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50087970 Cc1cccc(C)c1C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(N)=O InChI=1S/C36H45N5O5/c1-21-10-8-11-22(2)28(21)20-30(33(38)43)39-34(44)31(18-25-12-6-5-7-13-25)40-35(45)32-14-9-15-41(32)36(46)29(37)19-27-23(3)16-26(42)17-24(27)4/h5-8,10-13,16-17,29-32,42H,9,14-15,18-20,37H2,1-4H3,(H2,38,43)(H,39,44)(H,40,45)/t29-,30-,31-,32-/m0/s1 CPQMYSRHKXCHJU-YDPTYEFTSA-N 50009265 CHEMBL3233194 Mu-type opioid receptor Cavia cutleri 249 ChEMBL 10.1016/j.bmc.2014.02.015 10.7270/Q29Z96DB 24613457 Cai, J; Song, B; Cai, Y; Ma, Y; Lam, AL; Magiera, J; Sekar, S; Wyse, BD; Ambo, A; Sasaki, Y; Lazarus, LH; Smith, MT; Li, T Nanjing Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009265 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009265&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655509 103922321 CHEMBL3233194 ZINC13823296 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50087971 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c(C)cc(O)cc1C)C(N)=O InChI=1S/C36H45N5O6/c1-20-13-25(42)14-21(2)27(20)18-29(37)36(47)41-12-8-11-32(41)35(46)40-31(17-24-9-6-5-7-10-24)34(45)39-30(33(38)44)19-28-22(3)15-26(43)16-23(28)4/h5-7,9-10,13-16,29-32,42-43H,8,11-12,17-19,37H2,1-4H3,(H2,38,44)(H,39,45)(H,40,46)/t29-,30-,31-,32-/m0/s1 FSDAHJDHUQDCNF-YDPTYEFTSA-N 50009266 CHEMBL3233195 Mu-type opioid receptor Cavia cutleri 45 ChEMBL 10.1016/j.bmc.2014.02.015 10.7270/Q29Z96DB 24613457 Cai, J; Song, B; Cai, Y; Ma, Y; Lam, AL; Magiera, J; Sekar, S; Wyse, BD; Ambo, A; Sasaki, Y; Lazarus, LH; Smith, MT; Li, T Nanjing Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009266 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009266&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655510 103922322 CHEMBL3233195 ZINC13823286 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50087972 Cc1cc(C)c(C[C@H](NC(=O)[C@H](Cc2c(C)cc(C)cc2C)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C(N)=O)c(C)c1 InChI=1S/C40H53N5O5/c1-21-12-23(3)31(24(4)13-21)19-34(37(42)47)43-38(48)35(20-32-25(5)14-22(2)15-26(32)6)44-39(49)36-10-9-11-45(36)40(50)33(41)18-30-27(7)16-29(46)17-28(30)8/h12-17,33-36,46H,9-11,18-20,41H2,1-8H3,(H2,42,47)(H,43,48)(H,44,49)/t33-,34-,35-,36-/m0/s1 PWXLLCXDDUKGRD-ZYADHFCISA-N 50009267 CHEMBL3233196 Mu-type opioid receptor Cavia cutleri 9.3 ChEMBL 10.1016/j.bmc.2014.02.015 10.7270/Q29Z96DB 24613457 Cai, J; Song, B; Cai, Y; Ma, Y; Lam, AL; Magiera, J; Sekar, S; Wyse, BD; Ambo, A; Sasaki, Y; Lazarus, LH; Smith, MT; Li, T Nanjing Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009267 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009267&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 86302341 103922323 CHEMBL3233196 ZINC13823298 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50087973 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O InChI=1S/C27H33N5O4/c1-15-10-18(33)11-16(2)20(15)13-21(28)27(36)32-9-5-8-24(32)26(35)31-23(25(29)34)12-17-14-30-22-7-4-3-6-19(17)22/h3-4,6-7,10-11,14,21,23-24,30,33H,5,8-9,12-13,28H2,1-2H3,(H2,29,34)(H,31,35)/t21-,23-,24-/m0/s1 GKVLXSNNBUSNOA-XWGVYQGASA-N 50009268 CHEMBL3233197 Mu-type opioid receptor Cavia cutleri 10 ChEMBL 10.1016/j.bmc.2014.02.015 10.7270/Q29Z96DB 24613457 Cai, J; Song, B; Cai, Y; Ma, Y; Lam, AL; Magiera, J; Sekar, S; Wyse, BD; Ambo, A; Sasaki, Y; Lazarus, LH; Smith, MT; Li, T Nanjing Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009268 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009268&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655511 103922324 CHEMBL3233197 ZINC13823321 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50087974 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1cccc2ccccc12)C(N)=O InChI=1S/C29H34N4O4/c1-17-13-21(34)14-18(2)23(17)16-24(30)29(37)33-12-6-11-26(33)28(36)32-25(27(31)35)15-20-9-5-8-19-7-3-4-10-22(19)20/h3-5,7-10,13-14,24-26,34H,6,11-12,15-16,30H2,1-2H3,(H2,31,35)(H,32,36)/t24-,25-,26-/m0/s1 OPLCYKYAOILVPS-GSDHBNRESA-N 50009269 CHEMBL3233198 Mu-type opioid receptor Cavia cutleri 4.6 ChEMBL 10.1016/j.bmc.2014.02.015 10.7270/Q29Z96DB 24613457 Cai, J; Song, B; Cai, Y; Ma, Y; Lam, AL; Magiera, J; Sekar, S; Wyse, BD; Ambo, A; Sasaki, Y; Lazarus, LH; Smith, MT; Li, T Nanjing Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009269 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009269&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 86302365 103922325 CHEMBL3233198 ZINC01894117 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50087975 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(N)=O InChI=1S/C29H34N4O4/c1-17-12-22(34)13-18(2)23(17)16-24(30)29(37)33-11-5-8-26(33)28(36)32-25(27(31)35)15-19-9-10-20-6-3-4-7-21(20)14-19/h3-4,6-7,9-10,12-14,24-26,34H,5,8,11,15-16,30H2,1-2H3,(H2,31,35)(H,32,36)/t24-,25-,26-/m0/s1 FVYRGRRGGSESBL-GSDHBNRESA-N 50009270 CHEMBL3233199 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1016/j.bmc.2014.02.015 10.7270/Q29Z96DB 24613457 Cai, J; Song, B; Cai, Y; Ma, Y; Lam, AL; Magiera, J; Sekar, S; Wyse, BD; Ambo, A; Sasaki, Y; Lazarus, LH; Smith, MT; Li, T Nanjing Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009270 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009270&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655512 103922326 CHEMBL3233199 ZINC13823303 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50087976 Cc1cc(C)c(C[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C(N)=O)c(C)c1 InChI=1S/C28H38N4O4/c1-15-9-16(2)22(17(3)10-15)14-24(26(30)34)31-27(35)25-7-6-8-32(25)28(36)23(29)13-21-18(4)11-20(33)12-19(21)5/h9-12,23-25,33H,6-8,13-14,29H2,1-5H3,(H2,30,34)(H,31,35)/t23-,24-,25-/m0/s1 XNBWKHVQZJPNPX-SDHOMARFSA-N 50009271 CHEMBL3233014 Mu-type opioid receptor Cavia cutleri 2.7 ChEMBL 10.1016/j.bmc.2014.02.015 10.7270/Q29Z96DB 24613457 Cai, J; Song, B; Cai, Y; Ma, Y; Lam, AL; Magiera, J; Sekar, S; Wyse, BD; Ambo, A; Sasaki, Y; Lazarus, LH; Smith, MT; Li, T Nanjing Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009271 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009271&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655513 103922327 CHEMBL3233014 ZINC13823343 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50087977 Cc1cccc(C)c1C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(N)=O InChI=1S/C27H36N4O4/c1-15-7-5-8-16(2)21(15)14-23(25(29)33)30-26(34)24-9-6-10-31(24)27(35)22(28)13-20-17(3)11-19(32)12-18(20)4/h5,7-8,11-12,22-24,32H,6,9-10,13-14,28H2,1-4H3,(H2,29,33)(H,30,34)/t22-,23-,24-/m0/s1 XAJGBUZQZJQFDK-HJOGWXRNSA-N 50009272 CHEMBL3233200 Mu-type opioid receptor Cavia cutleri 0.274000 ChEMBL 10.1016/j.bmc.2014.02.015 10.7270/Q29Z96DB 24613457 Cai, J; Song, B; Cai, Y; Ma, Y; Lam, AL; Magiera, J; Sekar, S; Wyse, BD; Ambo, A; Sasaki, Y; Lazarus, LH; Smith, MT; Li, T Nanjing Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009272 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009272&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655514 103922328 CHEMBL3233200 ZINC03642648 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50087978 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C25H32N4O4/c1-15-11-18(30)12-16(2)19(15)14-20(26)25(33)29-10-6-9-22(29)24(32)28-21(23(27)31)13-17-7-4-3-5-8-17/h3-5,7-8,11-12,20-22,30H,6,9-10,13-14,26H2,1-2H3,(H2,27,31)(H,28,32)/t20-,21-,22-/m0/s1 KHMNQJDESQDVPF-FKBYEOEOSA-N 50149381 1-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid ((S)-1-carbamoyl-2-phenyl-ethyl)-amide::CHEMBL120758 Mu-type opioid receptor Cavia cutleri 2.3 ChEMBL 10.1016/j.bmc.2014.02.015 10.7270/Q29Z96DB 24613457 Cai, J; Song, B; Cai, Y; Ma, Y; Lam, AL; Magiera, J; Sekar, S; Wyse, BD; Ambo, A; Sasaki, Y; Lazarus, LH; Smith, MT; Li, T Nanjing Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149381 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149381&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44346065 104037526 CHEMBL120758 ZINC13478592 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50086938 Cc1cccc(C)c1C[C@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C34H52N8O6/c1-19-9-7-10-20(2)25(19)18-29(32(46)41-28(33(47)48)11-5-6-13-35)42-31(45)27(12-8-14-39-34(37)38)40-30(44)26(36)17-24-21(3)15-23(43)16-22(24)4/h7,9-10,15-16,26-29,43H,5-6,8,11-14,17-18,35-36H2,1-4H3,(H,40,44)(H,41,46)(H,42,45)(H,47,48)(H4,37,38,39)/t26-,27+,28-,29-/m0/s1 MMMRATAUUXFRID-CRNKYVSFSA-N 50008834 CHEMBL3236671 Mu-type opioid receptor Cavia cutleri 2.0 ChEMBL 10.1016/j.bmc.2014.02.011 10.7270/Q20P11JG 24602401 Bai, L; Li, Z; Chen, J; Chung, NN; Wilkes, BC; Li, T; Schiller, PW Nanjing Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008834 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008834&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655411 242057304 CHEMBL3236671 C01960 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50086939 Cc1cc(C)c(C[C@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C(=O)N[C@@H](CCCCN)C(O)=O)c(C)c1 InChI=1S/C35H54N8O6/c1-19-13-20(2)26(21(3)14-19)18-30(33(47)42-29(34(48)49)9-6-7-11-36)43-32(46)28(10-8-12-40-35(38)39)41-31(45)27(37)17-25-22(4)15-24(44)16-23(25)5/h13-16,27-30,44H,6-12,17-18,36-37H2,1-5H3,(H,41,45)(H,42,47)(H,43,46)(H,48,49)(H4,38,39,40)/t27-,28+,29-,30-/m0/s1 HKAQHNOFQGGZDF-XJYHXZFBSA-N 50008835 CHEMBL3236672 Mu-type opioid receptor Cavia cutleri 17 ChEMBL 10.1016/j.bmc.2014.02.011 10.7270/Q20P11JG 24602401 Bai, L; Li, Z; Chen, J; Chung, NN; Wilkes, BC; Li, T; Schiller, PW Nanjing Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008835&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655412 242057305 CHEMBL3236672 C01960 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50086940 CC(C)c1cccc(C)c1C[C@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C36H56N8O6/c1-20(2)25-11-8-10-21(3)27(25)19-31(34(48)43-30(35(49)50)12-6-7-14-37)44-33(47)29(13-9-15-41-36(39)40)42-32(46)28(38)18-26-22(4)16-24(45)17-23(26)5/h8,10-11,16-17,20,28-31,45H,6-7,9,12-15,18-19,37-38H2,1-5H3,(H,42,46)(H,43,48)(H,44,47)(H,49,50)(H4,39,40,41)/t28-,29+,30-,31-/m0/s1 FWBKKQMWKRKOEQ-JVVMDBNWSA-N 50008836 CHEMBL3236673 Mu-type opioid receptor Cavia cutleri 0.828000 ChEMBL 10.1016/j.bmc.2014.02.011 10.7270/Q20P11JG 24602401 Bai, L; Li, Z; Chen, J; Chung, NN; Wilkes, BC; Li, T; Schiller, PW Nanjing Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008836&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655413 242057306 CHEMBL3236673 C01960 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50086941 CCc1cccc(C)c1C[C@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C35H54N8O6/c1-5-23-11-8-10-20(2)26(23)19-30(33(47)42-29(34(48)49)12-6-7-14-36)43-32(46)28(13-9-15-40-35(38)39)41-31(45)27(37)18-25-21(3)16-24(44)17-22(25)4/h8,10-11,16-17,27-30,44H,5-7,9,12-15,18-19,36-37H2,1-4H3,(H,41,45)(H,42,47)(H,43,46)(H,48,49)(H4,38,39,40)/t27-,28+,29-,30-/m0/s1 VPMPPAOHKTUTJH-XJYHXZFBSA-N 50008837 CHEMBL3236674 Mu-type opioid receptor Cavia cutleri 0.474000 ChEMBL 10.1016/j.bmc.2014.02.011 10.7270/Q20P11JG 24602401 Bai, L; Li, Z; Chen, J; Chung, NN; Wilkes, BC; Li, T; Schiller, PW Nanjing Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008837 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008837&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655414 242057307 CHEMBL3236674 C01960 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50086942 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cccc2ccccc12)C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C36H50N8O6/c1-21-17-25(45)18-22(2)27(21)20-28(38)32(46)42-29(14-8-16-41-36(39)40)33(47)44-31(34(48)43-30(35(49)50)13-5-6-15-37)19-24-11-7-10-23-9-3-4-12-26(23)24/h3-4,7,9-12,17-18,28-31,45H,5-6,8,13-16,19-20,37-38H2,1-2H3,(H,42,46)(H,43,48)(H,44,47)(H,49,50)(H4,39,40,41)/t28-,29+,30-,31-/m0/s1 XOKJUHKHJMOTKH-JVVMDBNWSA-N 50008838 CHEMBL3236675 Mu-type opioid receptor Cavia cutleri 1.9 ChEMBL 10.1016/j.bmc.2014.02.011 10.7270/Q20P11JG 24602401 Bai, L; Li, Z; Chen, J; Chung, NN; Wilkes, BC; Li, T; Schiller, PW Nanjing Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008838 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008838&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655415 242057308 CHEMBL3236675 C01960 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50086943 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C36H50N8O6/c1-21-16-26(45)17-22(2)27(21)20-28(38)32(46)42-29(11-7-15-41-36(39)40)33(47)44-31(34(48)43-30(35(49)50)10-5-6-14-37)19-23-12-13-24-8-3-4-9-25(24)18-23/h3-4,8-9,12-13,16-18,28-31,45H,5-7,10-11,14-15,19-20,37-38H2,1-2H3,(H,42,46)(H,43,48)(H,44,47)(H,49,50)(H4,39,40,41)/t28-,29+,30-,31-/m0/s1 ZVUDQBLUCSEYMI-JVVMDBNWSA-N 50008839 CHEMBL3236676 Mu-type opioid receptor Cavia cutleri 72 ChEMBL 10.1016/j.bmc.2014.02.011 10.7270/Q20P11JG 24602401 Bai, L; Li, Z; Chen, J; Chung, NN; Wilkes, BC; Li, T; Schiller, PW Nanjing Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008839 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008839&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655416 242057309 CHEMBL3236676 C01960 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50086944 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C34H49N9O6/c1-19-14-22(44)15-20(2)24(19)17-25(36)30(45)41-27(11-7-13-39-34(37)38)31(46)43-29(16-21-18-40-26-9-4-3-8-23(21)26)32(47)42-28(33(48)49)10-5-6-12-35/h3-4,8-9,14-15,18,25,27-29,40,44H,5-7,10-13,16-17,35-36H2,1-2H3,(H,41,45)(H,42,47)(H,43,46)(H,48,49)(H4,37,38,39)/t25-,27+,28-,29-/m0/s1 OZUVMQFMTPBKPC-JKWLULBVSA-N 50008840 CHEMBL3236677 Mu-type opioid receptor Cavia cutleri 1.1 ChEMBL 10.1016/j.bmc.2014.02.011 10.7270/Q20P11JG 24602401 Bai, L; Li, Z; Chen, J; Chung, NN; Wilkes, BC; Li, T; Schiller, PW Nanjing Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008840 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008840&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655417 242057310 CHEMBL3236677 C01960 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50086945 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C32H48N8O6/c1-19-15-22(41)16-20(2)23(19)18-24(34)28(42)38-25(12-8-14-37-32(35)36)29(43)40-27(17-21-9-4-3-5-10-21)30(44)39-26(31(45)46)11-6-7-13-33/h3-5,9-10,15-16,24-27,41H,6-8,11-14,17-18,33-34H2,1-2H3,(H,38,42)(H,39,44)(H,40,43)(H,45,46)(H4,35,36,37)/t24-,25+,26-,27-/m0/s1 YHUCQCOKZSACOI-XUJYPJAKSA-N 50008841 CHEMBL3236678 Mu-type opioid receptor Cavia cutleri 1.4 ChEMBL 10.1016/j.bmc.2014.02.011 10.7270/Q20P11JG 24602401 Bai, L; Li, Z; Chen, J; Chung, NN; Wilkes, BC; Li, T; Schiller, PW Nanjing Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008841 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008841&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11520197 242057311 CHEMBL3236678 C01960 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50090290 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C32H49N9O5/c1-19-15-22(42)16-20(2)23(19)18-24(34)29(44)40-26(12-8-14-38-32(36)37)30(45)41-27(17-21-9-4-3-5-10-21)31(46)39-25(28(35)43)11-6-7-13-33/h3-5,9-10,15-16,24-27,42H,6-8,11-14,17-18,33-34H2,1-2H3,(H2,35,43)(H,39,46)(H,40,44)(H,41,45)(H4,36,37,38)/t24-,25-,26+,27-/m0/s1 FIAKHZXVLBNZLW-NFGXINMFSA-N 50010483 CHEMBL2181202 Mu-type opioid receptor Cavia cutleri 1.4 ChEMBL 10.1021/ml4004765 10.7270/Q2VM4DSC 24839540 Ballet, S; Betti, C; Novoa, A; Tömböly, C; Nielsen, CU; Helms, HC; Lesniak, A; Kleczkowska, P; Chung, NN; Lipkowski, AW; Brodin, B; Tourwé, D; Schiller, PW Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010483&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9809562 242057631 CHEMBL2181202 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50090291 NCCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](N)Cc1ccc(OCc2cn(nn2)[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)cc1)C(N)=O InChI=1S/C39H58N12O10/c40-15-5-4-9-27(34(42)56)46-37(59)29(18-22-7-2-1-3-8-22)48-36(58)28(10-6-16-45-39(43)44)47-35(57)26(41)17-23-11-13-25(14-12-23)60-21-24-19-51(50-49-24)38-33(55)32(54)31(53)30(20-52)61-38/h1-3,7-8,11-14,19,26-33,38,52-55H,4-6,9-10,15-18,20-21,40-41H2,(H2,42,56)(H,46,59)(H,47,57)(H,48,58)(H4,43,44,45)/t26-,27-,28+,29-,30+,31-,32-,33+,38+/m0/s1 RFBNCSCKKPMRAN-WUJQGWQASA-N 50010484 CHEMBL3264358 Mu-type opioid receptor Cavia cutleri 1180 ChEMBL 10.1021/ml4004765 10.7270/Q2VM4DSC 24839540 Ballet, S; Betti, C; Novoa, A; Tömböly, C; Nielsen, CU; Helms, HC; Lesniak, A; Kleczkowska, P; Chung, NN; Lipkowski, AW; Brodin, B; Tourwé, D; Schiller, PW Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010484&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655802 242057632 CHEMBL3264358 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50090293 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cn(nn1)[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)C(N)=O InChI=1S/C37H53N11O10/c1-18-11-22(50)12-19(2)23(18)15-24(38)33(55)43-25(9-6-10-42-37(40)41)34(56)45-27(13-20-7-4-3-5-8-20)35(57)44-26(32(39)54)14-21-16-48(47-46-21)36-31(53)30(52)29(51)28(17-49)58-36/h3-5,7-8,11-12,16,24-31,36,49-53H,6,9-10,13-15,17,38H2,1-2H3,(H2,39,54)(H,43,55)(H,44,57)(H,45,56)(H4,40,41,42)/t24-,25+,26-,27-,28+,29-,30-,31+,36+/m0/s1 BNCUONHDNJHYQU-BXETYFKASA-N 50010486 CHEMBL3264359 Mu-type opioid receptor Cavia cutleri 0.660000 ChEMBL 10.1021/ml4004765 10.7270/Q2VM4DSC 24839540 Ballet, S; Betti, C; Novoa, A; Tömböly, C; Nielsen, CU; Helms, HC; Lesniak, A; Kleczkowska, P; Chung, NN; Lipkowski, AW; Brodin, B; Tourwé, D; Schiller, PW Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010486 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010486&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655803 242057633 CHEMBL3264359 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50090295 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cn(nn1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C(N)=O InChI=1S/C37H53N11O10/c1-18-11-22(50)12-19(2)23(18)15-24(38)33(55)43-25(9-6-10-42-37(40)41)34(56)45-27(13-20-7-4-3-5-8-20)35(57)44-26(32(39)54)14-21-16-48(47-46-21)36-31(53)30(52)29(51)28(17-49)58-36/h3-5,7-8,11-12,16,24-31,36,49-53H,6,9-10,13-15,17,38H2,1-2H3,(H2,39,54)(H,43,55)(H,44,57)(H,45,56)(H4,40,41,42)/t24-,25+,26-,27-,28+,29+,30-,31+,36+/m0/s1 BNCUONHDNJHYQU-ZHNJQXOLSA-N 50010487 CHEMBL3264360 Mu-type opioid receptor Cavia cutleri 1.5 ChEMBL 10.1021/ml4004765 10.7270/Q2VM4DSC 24839540 Ballet, S; Betti, C; Novoa, A; Tömböly, C; Nielsen, CU; Helms, HC; Lesniak, A; Kleczkowska, P; Chung, NN; Lipkowski, AW; Brodin, B; Tourwé, D; Schiller, PW Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010487 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010487&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655804 242057634 CHEMBL3264360 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50090300 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](COCc1cn(nn1)[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)C(N)=O InChI=1S/C38H55N11O11/c1-19-11-23(51)12-20(2)24(19)14-25(39)34(56)44-26(9-6-10-43-38(41)42)35(57)45-27(13-21-7-4-3-5-8-21)36(58)46-28(33(40)55)18-59-17-22-15-49(48-47-22)37-32(54)31(53)30(52)29(16-50)60-37/h3-5,7-8,11-12,15,25-32,37,50-54H,6,9-10,13-14,16-18,39H2,1-2H3,(H2,40,55)(H,44,56)(H,45,57)(H,46,58)(H4,41,42,43)/t25-,26+,27-,28-,29+,30-,31-,32+,37+/m0/s1 TUWFEWCOJOCTPR-UGEVMRFOSA-N 50010488 CHEMBL3264361 Mu-type opioid receptor Cavia cutleri 0.350000 ChEMBL 10.1021/ml4004765 10.7270/Q2VM4DSC 24839540 Ballet, S; Betti, C; Novoa, A; Tömböly, C; Nielsen, CU; Helms, HC; Lesniak, A; Kleczkowska, P; Chung, NN; Lipkowski, AW; Brodin, B; Tourwé, D; Schiller, PW Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010488 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010488&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655805 242057635 CHEMBL3264361 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50090302 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(OCc2cn(nn2)[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)cc1)C(N)=O InChI=1S/C44H59N11O11/c1-23-15-28(57)16-24(2)30(23)19-31(45)40(62)50-32(9-6-14-49-44(47)48)41(63)52-34(18-25-7-4-3-5-8-25)42(64)51-33(39(46)61)17-26-10-12-29(13-11-26)65-22-27-20-55(54-53-27)43-38(60)37(59)36(58)35(21-56)66-43/h3-5,7-8,10-13,15-16,20,31-38,43,56-60H,6,9,14,17-19,21-22,45H2,1-2H3,(H2,46,61)(H,50,62)(H,51,64)(H,52,63)(H4,47,48,49)/t31-,32+,33-,34-,35+,36-,37-,38+,43+/m0/s1 MZNMFJGGDGWUEZ-WJVBQHSPSA-N 50010489 CHEMBL3264362 Mu-type opioid receptor Cavia cutleri 2.3 ChEMBL 10.1021/ml4004765 10.7270/Q2VM4DSC 24839540 Ballet, S; Betti, C; Novoa, A; Tömböly, C; Nielsen, CU; Helms, HC; Lesniak, A; Kleczkowska, P; Chung, NN; Lipkowski, AW; Brodin, B; Tourwé, D; Schiller, PW Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010489 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010489&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655806 242057636 CHEMBL3264362 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50090321 NCCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O InChI=1S/C30H45N9O5/c31-15-5-4-9-23(26(33)41)37-29(44)25(18-19-7-2-1-3-8-19)39-28(43)24(10-6-16-36-30(34)35)38-27(42)22(32)17-20-11-13-21(40)14-12-20/h1-3,7-8,11-14,22-25,40H,4-6,9-10,15-18,31-32H2,(H2,33,41)(H,37,44)(H,38,42)(H,39,43)(H4,34,35,36)/t22-,23-,24+,25-/m0/s1 UEVAHGMTRWGMTB-JBXUNAHCSA-N 50016867 (S)-6-Amino-2-((S)-2-{(R)-2-[(S)-2-amino-3-(4-hydroxy-phenyl)-propionylamino]-5-guanidino-pentanoylamino}-3-phenyl-propionylamino)-hexanoic acid amide::6-amino-2-[1-[1-[1-amino-2-(4-hydroxyphenyl)-(1S)-ethylcarboxamido]-4-amino(imino)methylamino-(1R)-butylcarboxamido]-2-phenyl-(1S)-ethylcarboxamido]-(2S)-hexanamide::CHEMBL60444 Mu-type opioid receptor Cavia cutleri 254 ChEMBL 10.1021/ml4004765 10.7270/Q2VM4DSC 24839540 Ballet, S; Betti, C; Novoa, A; Tömböly, C; Nielsen, CU; Helms, HC; Lesniak, A; Kleczkowska, P; Chung, NN; Lipkowski, AW; Brodin, B; Tourwé, D; Schiller, PW Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016867&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 122222 103928212 CHEMBL60444 ZINC14951239 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50090495 CN([C@H](CN1CCCC1)c1cccc(NC(=O)[C@H](N)CC(O)=O)c1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C25H30Cl2N4O4/c1-30(23(32)12-16-7-8-19(26)20(27)11-16)22(15-31-9-2-3-10-31)17-5-4-6-18(13-17)29-25(35)21(28)14-24(33)34/h4-8,11,13,21-22H,2-3,9-10,12,14-15,28H2,1H3,(H,29,35)(H,33,34)/t21-,22-/m1/s1 FQLSJBIFAGFAMH-FGZHOGPDSA-N 50054440 (R)-3-Amino-N-[3-((S)-1-{[2-(3,4-dichloro-phenyl)-acetyl]-methyl-amino}-2-pyrrolidin-1-yl-ethyl)-phenyl]-succinamic acid::CHEMBL344885 Mu-type opioid receptor Cavia cutleri 280 ChEMBL 10.1021/jm960459x 10.7270/Q2N878WW 8893842 Chang, AC; Cowan, A; Takemori, AE; Portoghese, PS University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054440 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054440&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10346615 103951071 CHEMBL344885 ZINC03952259 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50090496 CN([C@H](CN1CCCC1)c1cccc(NC(=O)[C@@H](N)CC(O)=O)c1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C25H30Cl2N4O4/c1-30(23(32)12-16-7-8-19(26)20(27)11-16)22(15-31-9-2-3-10-31)17-5-4-6-18(13-17)29-25(35)21(28)14-24(33)34/h4-8,11,13,21-22H,2-3,9-10,12,14-15,28H2,1H3,(H,29,35)(H,33,34)/t21-,22+/m0/s1 FQLSJBIFAGFAMH-FCHUYYIVSA-N 50054439 (S)-3-Amino-N-[3-((S)-1-{[2-(3,4-dichloro-phenyl)-acetyl]-methyl-amino}-2-pyrrolidin-1-yl-ethyl)-phenyl]-succinamic acid::CHEMBL138547 Mu-type opioid receptor Cavia cutleri 462 ChEMBL 10.1021/jm960459x 10.7270/Q2N878WW 8893842 Chang, AC; Cowan, A; Takemori, AE; Portoghese, PS University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054439 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054439&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9871376 103951070 CHEMBL138547 ZINC03952258 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50096512 CO[C@]12C=C[C@@]3(C[C@@H]1[C@@H](O)c1ccccc1)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45 InChI=1S/C30H33NO4/c1-34-30-12-11-28(16-21(30)25(33)19-5-3-2-4-6-19)23-15-20-9-10-22(32)26-24(20)29(28,27(30)35-26)13-14-31(23)17-18-7-8-18/h2-6,9-12,18,21,23,25,27,32-33H,7-8,13-17H2,1H3/t21-,23-,25+,27-,28-,29+,30-/m1/s1 KLULJLHFQXPFIW-RNOORVPFSA-N 50015006 CHEMBL3262360 Mu-type opioid receptor Cavia cutleri 0.800000 ChEMBL 10.1021/jm401964y 10.7270/Q2NG4S62 24761755 Kumar, V; Ridzwan, IE; Grivas, K; Lewis, JW; Clark, MJ; Meurice, C; Jimenez-Gomez, C; Pogozheva, I; Mosberg, H; Traynor, JR; Husbands, SM University of Bath http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015006 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015006&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 90306838 242058543 CHEMBL3262360 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50092512 CC(C)[C@@H](CN1CC[C@](C)([C@@H](C)C1)c1cccc(O)c1)NC(=O)[C@H]1Cc2ccc(O)cc2CN1 InChI=1S/C28H39N3O3/c1-18(2)26(30-27(34)25-13-20-8-9-24(33)12-21(20)15-29-25)17-31-11-10-28(4,19(3)16-31)22-6-5-7-23(32)14-22/h5-9,12,14,18-19,25-26,29,32-33H,10-11,13,15-17H2,1-4H3,(H,30,34)/t19-,25+,26+,28+/m0/s1 ZLVXBBHTMQJRSX-VMGNSXQWSA-N 50130563 (3R)-7-Hydroxy-N-[(1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide::(3R)-7-hydroxy-N-(1S)-1-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl-2-methylpropyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide::(3R)-7-hydroxy-N-[(1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide::(R)-7-hydroxy-N-((S)-1-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)-3-methylbutan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::7-Hydroxy-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid {(S)-1-[(3R,4R)-4-(3-hydroxy-phenyl)-3,4-dimethyl-piperidin-1-ylmethyl]-2-methyl-propyl}-amide::7-Hydroxy-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid {1-[4-(3-hydroxy-phenyl)-3,4-dimethyl-piperidin-1-ylmethyl]-2-methyl-propyl}-amide::CHEMBL415247::atrans-(3R,4R)-dimethyl-4-(3-hydroxyphenyl) piperidine Mu-type opioid receptor Cavia cutleri 2.2 ChEMBL 10.1016/j.bmcl.2014.03.040 10.7270/Q2222WBX 24690494 Urbano, M; Guerrero, M; Rosen, H; Roberts, E The Scripps Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130563&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search JDC 6VI4,4DJH 9956146 104021877 CHEMBL415247 7362 ZINC36215338 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50119252 C[C@H]1[C@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C18H25NO/c1-12-17-9-14-5-6-15(20)10-16(14)18(12,2)7-8-19(17)11-13-3-4-13/h5-6,10,12-13,17,20H,3-4,7-9,11H2,1-2H3/t12-,17?,18-/m0/s1 YQYVFVRQLZMJKJ-PEYLTSRESA-N 50083926 (6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::(SSR)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyclo[9.1.1.0*3,8*]trideca-3(8),4,6-trien-6-ol(cyclazocine)::(cyclazocine)2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid::10-cyclopropylmethyl-1,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol(Cyclazocine)::3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol (cyclazocine)::3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Cyclazocine)::3-Cyclopropylmethyl-8-hydroxy-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocinium::3-Cyclopropylmethyl-8-hydroxy-6,11-dimethyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one ((-)cyclazocine)::BDBM50451129::CHEMBL3085528::CYCLAZOCINE Mu-type opioid receptor Cavia cutleri 0.320000 ChEMBL 10.1016/s0960-894x(01)00014-2 10.7270/Q2542MVZ 11266156 Wentland, MP; Lou, R; Ye, Y; Cohen, DJ; Richardson, GP; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083926 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083926&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10016044 103983527 CHEMBL3085528 ZINC01699599 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50119253 C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@@]1(C)CN2CC1CC1 InChI=1S/C17H23NO/c1-11-16-7-13-5-6-14(19)8-15(13)17(11,2)10-18(16)9-12-3-4-12/h5-6,8,11-12,16,19H,3-4,7,9-10H2,1-2H3/t11-,16+,17+/m1/s1 LSQSRZOMUOOWDV-NVGVWMPQSA-N 50001040 6,11-Dimethyl-3-(3-methyl-butyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL2021605 Mu-type opioid receptor Cavia cutleri 360 ChEMBL 10.1016/s0960-894x(01)00014-2 10.7270/Q2542MVZ 11266156 Wentland, MP; Lou, R; Ye, Y; Cohen, DJ; Richardson, GP; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001040 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001040&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 70696030 103915573 CHEMBL2021605 ZINC13726124 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121416 C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)N(C)C InChI=1S/C20H30N2/c1-14-19-11-16-7-8-17(21(3)4)12-18(16)20(14,2)9-10-22(19)13-15-5-6-15/h7-8,12,14-15,19H,5-6,9-11,13H2,1-4H3/t14-,19?,20-/m0/s1 YXOMKMVDHCVFCR-JUJMCKSGSA-N 50085022 ((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-dimethyl-amine::(3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-dimethyl-amine::(3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-dimethyl-amine.2HCl::CHEMBL299114 Mu-type opioid receptor Cavia cutleri 46 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085022 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085022&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44298207 103984505 CHEMBL299114 ZINC13493437 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121417 COc1cccc(Nc2ccc3CC4[C@H](C)[C@](C)(CCN4CC4CC4)c3c2)c1 InChI=1S/C25H32N2O/c1-17-24-13-19-9-10-21(26-20-5-4-6-22(14-20)28-3)15-23(19)25(17,2)11-12-27(24)16-18-7-8-18/h4-6,9-10,14-15,17-18,24,26H,7-8,11-13,16H2,1-3H3/t17-,24?,25-/m0/s1 FNGNAZDYQMZFAQ-BKYMLMSRSA-N 50123993 (3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-(3-methoxy-phenyl)-amine::CHEMBL169345 Mu-type opioid receptor Cavia cutleri 1.8 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123993&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44381519 104016360 CHEMBL169345 ZINC27981216 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121419 C[C@H]1C2Cc3ccc(NCc4ccc(Cl)cc4)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C25H31ClN2/c1-17-24-13-20-7-10-22(27-15-18-5-8-21(26)9-6-18)14-23(20)25(17,2)11-12-28(24)16-19-3-4-19/h5-10,14,17,19,24,27H,3-4,11-13,15-16H2,1-2H3/t17-,24?,25-/m0/s1 JIFZQSNBCYYAEQ-BKYMLMSRSA-N 50124001 (4-Chloro-benzyl)-(3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-amine::CHEMBL353938 Mu-type opioid receptor Cavia cutleri 8.8 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124001 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124001&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44381360 104016368 CHEMBL353938 ZINC27979147 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121420 C[C@H]1C2Cc3ccc(Nc4ccc(cc4)C(C)(C)C)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C28H38N2/c1-19-26-16-21-8-11-24(29-23-12-9-22(10-13-23)27(2,3)4)17-25(21)28(19,5)14-15-30(26)18-20-6-7-20/h8-13,17,19-20,26,29H,6-7,14-16,18H2,1-5H3/t19-,26?,28-/m0/s1 BBYJALUXOFWWNF-AFYHLXEZSA-N 50123999 (4-tert-Butyl-phenyl)-(3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-amine::CHEMBL352827 Mu-type opioid receptor Cavia cutleri 18 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123999 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123999&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44381517 104016366 CHEMBL352827 ZINC27981205 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121421 COc1ccccc1Nc1ccc2CC3[C@H](C)[C@](C)(CCN3CC3CC3)c2c1 InChI=1S/C25H32N2O/c1-17-23-14-19-10-11-20(26-22-6-4-5-7-24(22)28-3)15-21(19)25(17,2)12-13-27(23)16-18-8-9-18/h4-7,10-11,15,17-18,23,26H,8-9,12-14,16H2,1-3H3/t17-,23?,25-/m0/s1 MRUCLZDFQFDDHX-DQNHKJGCSA-N 50123998 (3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-(2-methoxy-phenyl)-amine::CHEMBL353303 Mu-type opioid receptor Cavia cutleri 8.5 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123998 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123998&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44381518 104016365 CHEMBL353303 ZINC27981210 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121422 C[C@H]1C2N(CC3CC3)CC[C@]1(C)c1cc(N)ccc1C2=O InChI=1S/C18H24N2O/c1-11-16-17(21)14-6-5-13(19)9-15(14)18(11,2)7-8-20(16)10-12-3-4-12/h5-6,9,11-12,16H,3-4,7-8,10,19H2,1-2H3/t11-,16?,18-/m0/s1 NVNLCWUDSURWQS-GQWBRKQSSA-N 50124002 8-Amino-3-cyclopropylmethyl-6,11-dimethyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::CHEMBL422560 Mu-type opioid receptor Cavia cutleri 3.6 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124002 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124002&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10334091 104016369 CHEMBL422560 ZINC27903568 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121423 C[C@H]1C2Cc3ccc(NCCc4ccccc4)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C26H34N2/c1-19-25-16-22-10-11-23(27-14-12-20-6-4-3-5-7-20)17-24(22)26(19,2)13-15-28(25)18-21-8-9-21/h3-7,10-11,17,19,21,25,27H,8-9,12-16,18H2,1-2H3/t19-,25?,26-/m0/s1 CBEQNEFYEBRKMD-JKEZHHNBSA-N 50085023 ((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-phenethyl-amine::(3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-phenethyl-amine::CHEMBL56165 Mu-type opioid receptor Cavia cutleri 9 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085023&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44298221 103984506 CHEMBL56165 ZINC29553517 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121424 C[C@H]1C2Cc3ccc(N)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C18H26N2/c1-12-17-9-14-5-6-15(19)10-16(14)18(12,2)7-8-20(17)11-13-3-4-13/h5-6,10,12-13,17H,3-4,7-9,11,19H2,1-2H3/t12-,17?,18-/m0/s1 STNPURITMRUHGJ-PEYLTSRESA-N 50085024 (6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ylamine::3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ylamine::3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ylamine.2HCl::CHEMBL52399 Mu-type opioid receptor Cavia cutleri 9.5 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085024&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44298187 103984507 CHEMBL52399 ZINC13493410 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121425 CC(C)Nc1ccc2CC3[C@H](C)[C@](C)(CCN3CC3CC3)c2c1 InChI=1S/C21H32N2/c1-14(2)22-18-8-7-17-11-20-15(3)21(4,19(17)12-18)9-10-23(20)13-16-5-6-16/h7-8,12,14-16,20,22H,5-6,9-11,13H2,1-4H3/t15-,20?,21-/m0/s1 MJVYKOPUBZDGOV-FRIMRSDBSA-N 50085031 ((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-isopropyl-amine::(3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-isopropyl-amine::CHEMBL55434 Mu-type opioid receptor Cavia cutleri 240 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085031&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44298240 103984514 CHEMBL55434 ZINC29550081 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121435 C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)N1CCCC1 InChI=1S/C22H32N2/c1-16-21-13-18-7-8-19(23-10-3-4-11-23)14-20(18)22(16,2)9-12-24(21)15-17-5-6-17/h7-8,14,16-17,21H,3-6,9-13,15H2,1-2H3/t16-,21?,22-/m0/s1 RHNGZRXXVLXNOE-URJRECBDSA-N 50085025 (6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-8-pyrrolidin-1-yl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::3-Cyclopropylmethyl-6,11-dimethyl-8-pyrrolidin-1-yl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::CHEMBL55948 Mu-type opioid receptor Cavia cutleri 770 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085025&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44298206 103984508 CHEMBL55948 ZINC29547240 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121437 C[C@H]1C2Cc3ccc(Nc4ccc(cc4)N(C)C)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C26H35N3/c1-18-25-15-20-7-8-22(27-21-9-11-23(12-10-21)28(3)4)16-24(20)26(18,2)13-14-29(25)17-19-5-6-19/h7-12,16,18-19,25,27H,5-6,13-15,17H2,1-4H3/t18-,25?,26-/m0/s1 MUBKMIVBISNFDP-XLXODUMSSA-N 50124005 CHEMBL440196::N-(3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-N',N'-dimethyl-benzene-1,4-diamine Mu-type opioid receptor Cavia cutleri 70 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124005 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124005&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44381356 104016372 CHEMBL440196 ZINC27988525 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121438 C[C@H]1C2Cc3ccc(Nc4ccc(cc4)C(F)(F)F)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C25H29F3N2/c1-16-23-13-18-5-8-21(29-20-9-6-19(7-10-20)25(26,27)28)14-22(18)24(16,2)11-12-30(23)15-17-3-4-17/h5-10,14,16-17,23,29H,3-4,11-13,15H2,1-2H3/t16-,23?,24-/m0/s1 CKJUZFCBVAZGEM-VHWFRIBGSA-N 50123990 (3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-(4-trifluoromethyl-phenyl)-amine::CHEMBL169670 Mu-type opioid receptor Cavia cutleri 13 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123990 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123990&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44381357 104016357 CHEMBL169670 ZINC27988531 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121440 C[C@H]1C2Cc3ccc(Nc4ccc(C)cc4)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C25H32N2/c1-17-4-9-21(10-5-17)26-22-11-8-20-14-24-18(2)25(3,23(20)15-22)12-13-27(24)16-19-6-7-19/h4-5,8-11,15,18-19,24,26H,6-7,12-14,16H2,1-3H3/t18-,24?,25-/m0/s1 DQKXDKCNNDHSMJ-VNYPPZAHSA-N 50123988 (3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-p-tolyl-amine::CHEMBL355403 Mu-type opioid receptor Cavia cutleri 0.910000 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123988 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123988&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44381336 104016355 CHEMBL355403 ZINC27987917 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121441 C[C@H]1C2Cc3ccc(Nc4ccc(Cl)cc4)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C24H29ClN2/c1-16-23-13-18-5-8-21(26-20-9-6-19(25)7-10-20)14-22(18)24(16,2)11-12-27(23)15-17-3-4-17/h5-10,14,16-17,23,26H,3-4,11-13,15H2,1-2H3/t16-,23?,24-/m0/s1 TZQRWOINOMYXDT-VHWFRIBGSA-N 50123996 (4-Chloro-phenyl)-(3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-amine::CHEMBL169030 Mu-type opioid receptor Cavia cutleri 3 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123996&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44381337 104016363 CHEMBL169030 ZINC27979402 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121447 C[C@H]1[C@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2C[C@@H]1CCCO1 InChI=1S/C19H27NO2/c1-13-18-10-14-5-6-15(21)11-17(14)19(13,2)7-8-20(18)12-16-4-3-9-22-16/h5-6,11,13,16,18,21H,3-4,7-10,12H2,1-2H3/t13-,16-,18+,19-/m0/s1 NLKLXMMOJZHSCB-IVJVFBROSA-N 50007102 6,11-Dimethyl-3-(tetrahydro-furan-2-ylmethyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL79470::MR-2034 Mu-type opioid receptor Cavia cutleri 0.170000 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007102 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007102&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 68196155 103920385 CHEMBL79470 ZINC13493451 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121448 C[C@H]1C2Cc3ccc(Nc4ccc(Cl)c(Cl)c4)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C24H28Cl2N2/c1-15-23-11-17-5-6-18(27-19-7-8-21(25)22(26)13-19)12-20(17)24(15,2)9-10-28(23)14-16-3-4-16/h5-8,12-13,15-16,23,27H,3-4,9-11,14H2,1-2H3/t15-,23?,24-/m0/s1 DQCFFESGZOYPIK-BERSIMOUSA-N 50124008 (3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-(3,4-dichloro-phenyl)-amine::CHEMBL168392 Mu-type opioid receptor Cavia cutleri 8.4 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124008 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124008&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44381349 104016375 CHEMBL168392 ZINC27981696 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121451 CC[C@]12CCN(CC3CC3)C([C@@H]1C)C(=O)c1ccc(O)cc21 InChI=1S/C19H25NO2/c1-3-19-8-9-20(11-13-4-5-13)17(12(19)2)18(22)15-7-6-14(21)10-16(15)19/h6-7,10,12-13,17,21H,3-5,8-9,11H2,1-2H3/t12-,17?,19-/m0/s1 SEJUQQOPVAUETF-BKBNBNODSA-N 50000091 (6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::(6S,11R)-3-Cyclopropylmethyl-9-hydroxy-6,11-dimethyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one (ethylketocyclazocine)::3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one(Ethylketazocine, EKC)::CHEMBL279968::EKC::EKC(-) Mu-type opioid receptor Cavia cutleri 0.780000 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000091&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44273397 103914788 CHEMBL279968 ZINC00967957 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121457 COc1ccc(Nc2ccc3CC4[C@H](C)[C@](C)(CCN4CC4CC4)c3c2)cc1 InChI=1S/C25H32N2O/c1-17-24-14-19-6-7-21(26-20-8-10-22(28-3)11-9-20)15-23(19)25(17,2)12-13-27(24)16-18-4-5-18/h6-11,15,17-18,24,26H,4-5,12-14,16H2,1-3H3/t17-,24?,25-/m0/s1 DJFFPOVRKTXBHV-BKYMLMSRSA-N 50123995 (3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-(4-methoxy-phenyl)-amine::CHEMBL169536 Mu-type opioid receptor Cavia cutleri 0.470000 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123995 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123995&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44381335 104016362 CHEMBL169536 ZINC27987884 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121463 CC[C@]12CCN(CC3CC3)C([C@@H]1C)C(=O)c1ccc(Nc3ccccc3)cc21 InChI=1S/C25H30N2O/c1-3-25-13-14-27(16-18-9-10-18)23(17(25)2)24(28)21-12-11-20(15-22(21)25)26-19-7-5-4-6-8-19/h4-8,11-12,15,17-18,23,26H,3,9-10,13-14,16H2,1-2H3/t17-,23?,25-/m0/s1 YCJIZJTVBUVHIS-DQNHKJGCSA-N 50123992 3-Cyclopropylmethyl-6-ethyl-11-methyl-8-phenylamino-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::CHEMBL352965 Mu-type opioid receptor Cavia cutleri 10 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123992&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380994 104016359 CHEMBL352965 ZINC27981866 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121488 CC[C@]12CCN(CC3CC3)C([C@@H]1C)C(=O)c1ccc(N)cc21 InChI=1S/C19H26N2O/c1-3-19-8-9-21(11-13-4-5-13)17(12(19)2)18(22)15-7-6-14(20)10-16(15)19/h6-7,10,12-13,17H,3-5,8-9,11,20H2,1-2H3/t12-,17?,19-/m0/s1 VPXQAIQQOWVVPG-BKBNBNODSA-N 50123994 8-Amino-3-cyclopropylmethyl-6-ethyl-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::CHEMBL169346 Mu-type opioid receptor Cavia cutleri 17.0 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123994&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11779453 104016361 CHEMBL169346 ZINC27981872 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121497 C[C@H]1C2Cc3ccc(Nc4ccccn4)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C23H29N3/c1-16-21-13-18-8-9-19(25-22-5-3-4-11-24-22)14-20(18)23(16,2)10-12-26(21)15-17-6-7-17/h3-5,8-9,11,14,16-17,21H,6-7,10,12-13,15H2,1-2H3,(H,24,25)/t16-,21?,23-/m0/s1 HLMYKOIAIPZOSV-NFGFVTGESA-N 50123989 (3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-pyridin-2-yl-amine::CHEMBL422567 Mu-type opioid receptor Cavia cutleri 4.2 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123989 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123989&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44381023 104016356 CHEMBL422567 ZINC27987652 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121511 C[C@H]1C2Cc3ccc(NCc4ccccc4)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C25H32N2/c1-18-24-14-21-10-11-22(26-16-19-6-4-3-5-7-19)15-23(21)25(18,2)12-13-27(24)17-20-8-9-20/h3-7,10-11,15,18,20,24,26H,8-9,12-14,16-17H2,1-2H3/t18-,24?,25-/m0/s1 BZXKIAFEGKPVMG-VNYPPZAHSA-N 50085021 Benzyl-((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-amine::Benzyl-(3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-amine::Benzyl-(3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-amine.2HCl::CHEMBL301835 Mu-type opioid receptor Cavia cutleri 0.670 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085021&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10473705 103984504 CHEMBL301835 ZINC13493431 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121519 C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@@]1(C)CN2CC1CC1 InChI=1S/C17H23NO/c1-11-16-7-13-5-6-14(19)8-15(13)17(11,2)10-18(16)9-12-3-4-12/h5-6,8,11-12,16,19H,3-4,7,9-10H2,1-2H3/t11-,16+,17+/m1/s1 LSQSRZOMUOOWDV-NVGVWMPQSA-N 50001040 6,11-Dimethyl-3-(3-methyl-butyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL2021605 Mu-type opioid receptor Cavia cutleri 360 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001040 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001040&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 70696030 103915573 CHEMBL2021605 ZINC13726124 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121536 C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)N1CCCCC1 InChI=1S/C23H34N2/c1-17-22-14-19-8-9-20(24-11-4-3-5-12-24)15-21(19)23(17,2)10-13-25(22)16-18-6-7-18/h8-9,15,17-18,22H,3-7,10-14,16H2,1-2H3/t17-,22?,23-/m0/s1 DINHVBGJVOAMBL-XHLMSTEBSA-N 50085032 (6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-8-piperidin-1-yl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine; dihydrochloride::CHEMBL168625::CHEMBL543563 Mu-type opioid receptor Cavia cutleri 95 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085032&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44298213 103984515 CHEMBL543563CHEMBL168625 ZINC27901463 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50120527 CC1(C)SC[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H]1NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C28H35N5O7S/c1-28(2)23(33-24(36)19(29)12-17-8-10-18(34)11-9-17)26(38)30-14-22(35)31-20(13-16-6-4-3-5-7-16)25(37)32-21(15-41-28)27(39)40/h3-11,19-21,23,34H,12-15,29H2,1-2H3,(H,30,38)(H,31,35)(H,32,37)(H,33,36)(H,39,40)/t19-,20-,21-,23-/m0/s1 YTIQLGJTYUBFNI-FKEBYFGASA-N 50117262 12-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-6-benzyl-13,13-dimethyl-5,8,11-trioxo-1-thia-4,7,10-triaza-cyclotridecane-3-carboxylic acid::CHEMBL331043 Mu-type opioid receptor Cavia cutleri 82 ChEMBL 10.1021/jm020108k 10.7270/Q2RN376Q 12166947 Rew, Y; Malkmus, S; Svensson, C; Yaksh, TL; Chung, NN; Schiller, PW; Cassel, JA; DeHaven, RN; Taulane, JP; Goodman, M University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117262 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117262&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10031234 104010835 CHEMBL331043 ZINC27202671 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50120530 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 59 ChEMBL 10.1021/jm020108k 10.7270/Q2RN376Q 12166947 Rew, Y; Malkmus, S; Svensson, C; Yaksh, TL; Chung, NN; Schiller, PW; Cassel, JA; DeHaven, RN; Taulane, JP; Goodman, M University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50120533 CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23-,24-/m0/s1 MCMMCRYPQBNCPH-DVKRWUGUSA-N 50001683 13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid::7-Benzyl-10-{[3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL294616::DPDPE Mu-type opioid receptor Cavia cutleri 7300 ChEMBL 10.1021/jm020108k 10.7270/Q2RN376Q 12166947 Rew, Y; Malkmus, S; Svensson, C; Yaksh, TL; Chung, NN; Schiller, PW; Cassel, JA; DeHaven, RN; Taulane, JP; Goodman, M University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001683&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299404 103916113 CHEMBL294616 ZINC27520031 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50120535 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CSC[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC1=O)C(O)=O InChI=1S/C26H31N5O7S/c27-18(10-16-6-8-17(32)9-7-16)23(34)30-20-13-39-14-21(26(37)38)31-25(36)19(11-15-4-2-1-3-5-15)29-22(33)12-28-24(20)35/h1-9,18-21,32H,10-14,27H2,(H,28,35)(H,29,33)(H,30,34)(H,31,36)(H,37,38)/t18-,19-,20+,21+/m0/s1 CDLZQEQEXGEUBL-UWHLTILDSA-N 50117261 12-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-6-benzyl-5,8,11-trioxo-1-thia-4,7,10-triaza-cyclotridecane-3-carboxylic acid::CHEMBL122321 Mu-type opioid receptor Cavia cutleri 0.560000 ChEMBL 10.1021/jm020108k 10.7270/Q2RN376Q 12166947 Rew, Y; Malkmus, S; Svensson, C; Yaksh, TL; Chung, NN; Schiller, PW; Cassel, JA; DeHaven, RN; Taulane, JP; Goodman, M University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117261 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117261&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11146107 104010834 CHEMBL122321 ZINC27204617 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50120536 CC1(C)SC[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H]1NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C28H35N5O7S/c1-28(2)23(33-24(36)19(29)12-17-8-10-18(34)11-9-17)26(38)30-14-22(35)31-20(13-16-6-4-3-5-7-16)25(37)32-21(15-41-28)27(39)40/h3-11,19-21,23,34H,12-15,29H2,1-2H3,(H,30,38)(H,31,35)(H,32,37)(H,33,36)(H,39,40)/t19-,20-,21+,23-/m0/s1 YTIQLGJTYUBFNI-QXUYBEEESA-N 50117264 12-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-6-benzyl-13,13-dimethyl-5,8,11-trioxo-1-thia-4,7,10-triaza-cyclotridecane-3-carboxylic acid::CHEMBL122981 Mu-type opioid receptor Cavia cutleri 730 ChEMBL 10.1021/jm020108k 10.7270/Q2RN376Q 12166947 Rew, Y; Malkmus, S; Svensson, C; Yaksh, TL; Chung, NN; Schiller, PW; Cassel, JA; DeHaven, RN; Taulane, JP; Goodman, M University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117264 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117264&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10415925 104010837 CHEMBL122981 ZINC53186233 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50120538 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC1=O)C(O)=O InChI=1S/C26H31N5O7S/c27-18(10-16-6-8-17(32)9-7-16)23(34)30-20-13-39-14-21(26(37)38)31-25(36)19(11-15-4-2-1-3-5-15)29-22(33)12-28-24(20)35/h1-9,18-21,32H,10-14,27H2,(H,28,35)(H,29,33)(H,30,34)(H,31,36)(H,37,38)/t18-,19-,20+,21-/m0/s1 CDLZQEQEXGEUBL-BURNTYAHSA-N 50117263 (3R,6S,12S)-12-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-6-benzyl-5,8,11-trioxo-1-thia-4,7,10-triaza-cyclotridecane-3-carboxylic acid::12-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-6-benzyl-5,8,11-trioxo-1-thia-4,7,10-triaza-cyclotridecane-3-carboxylic acid::CHEMBL420903 Mu-type opioid receptor Cavia cutleri 1.1 ChEMBL 10.1021/jm020108k 10.7270/Q2RN376Q 12166947 Rew, Y; Malkmus, S; Svensson, C; Yaksh, TL; Chung, NN; Schiller, PW; Cassel, JA; DeHaven, RN; Taulane, JP; Goodman, M University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117263 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117263&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11071778 104010836 CHEMBL420903 ZINC27203006 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121596 CCNc1ccc2CC3[C@H](C)[C@](C)(CCN3CC3CC3)c2c1 InChI=1S/C20H30N2/c1-4-21-17-8-7-16-11-19-14(2)20(3,18(16)12-17)9-10-22(19)13-15-5-6-15/h7-8,12,14-15,19,21H,4-6,9-11,13H2,1-3H3/t14-,19?,20-/m0/s1 OLPQWIWZIFECJG-JUJMCKSGSA-N 50085028 ((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-ethyl-amine::(3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-ethyl-amine::CHEMBL55851 Mu-type opioid receptor Cavia cutleri 5.1 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085028&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44298198 103984511 CHEMBL55851 ZINC29550565 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121669 C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)N=C(c1ccccc1)c1ccccc1 InChI=1S/C31H34N2/c1-22-29-19-26-15-16-27(20-28(26)31(22,2)17-18-33(29)21-23-13-14-23)32-30(24-9-5-3-6-10-24)25-11-7-4-8-12-25/h3-12,15-16,20,22-23,29H,13-14,17-19,21H2,1-2H3/t22-,29?,31-/m0/s1 NNCHBNDFXOMUBO-JLWDABTHSA-N 50124006 Benzhydrylidene-(3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-amine::CHEMBL354322 Mu-type opioid receptor Cavia cutleri 360 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124006 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124006&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380931 104016373 CHEMBL354322 ZINC27981535 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121673 C[C@H]1[C@H]2Cc3ccc(N)cc3[C@@]1(C)CCN2C[C@@H]1CCCO1 InChI=1S/C19H28N2O/c1-13-18-10-14-5-6-15(20)11-17(14)19(13,2)7-8-21(18)12-16-4-3-9-22-16/h5-6,11,13,16,18H,3-4,7-10,12,20H2,1-2H3/t13-,16-,18+,19-/m0/s1 LVZWQSSWZVLAGU-IVJVFBROSA-N 50124009 6,11-Dimethyl-3-(tetrahydro-furan-2-ylmethyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ylamine::CHEMBL2368317 Mu-type opioid receptor Cavia cutleri 14 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124009 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124009&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73354381 104016376 CHEMBL2368317 ZINC13493452 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121675 C[C@H]1[C@H]2Cc3ccc(Nc4ccccc4)cc3[C@@]1(C)CCN2C[C@@H]1CCCO1 InChI=1S/C25H32N2O/c1-18-24-15-19-10-11-21(26-20-7-4-3-5-8-20)16-23(19)25(18,2)12-13-27(24)17-22-9-6-14-28-22/h3-5,7-8,10-11,16,18,22,24,26H,6,9,12-15,17H2,1-2H3/t18-,22-,24+,25-/m0/s1 CWKBPHXRHSDCRL-VVYCWGTDSA-N 50124007 CHEMBL2368318::[6,11-Dimethyl-3-(tetrahydro-furan-2-ylmethyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl]-phenyl-amine Mu-type opioid receptor Cavia cutleri 2.8 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124007 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124007&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73354382 104016374 CHEMBL2368318 ZINC13493453 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121676 C[C@H]1[C@H]2Cc3ccc(Nc4ccccc4)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C24H30N2/c1-17-23-14-19-10-11-21(25-20-6-4-3-5-7-20)15-22(19)24(17,2)12-13-26(23)16-18-8-9-18/h3-7,10-11,15,17-18,23,25H,8-9,12-14,16H2,1-2H3/t17-,23?,24-/m0/s1 FUMBLBJFVJXVBV-LZCUNHEZSA-N 50085020 ((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-phenyl-amine::(3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-phenyl-amine::CHEMBL2367916 Mu-type opioid receptor Cavia cutleri 1.10 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085020&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73351393 103984503 CHEMBL2367916 ZINC13493416 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121677 C[C@H]1[C@H]2Cc3ccc(N)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C18H26N2/c1-12-17-9-14-5-6-15(19)10-16(14)18(12,2)7-8-20(17)11-13-3-4-13/h5-6,10,12-13,17H,3-4,7-9,11,19H2,1-2H3/t12-,17+,18-/m0/s1 STNPURITMRUHGJ-RZAIGCCYSA-N 50092176 3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ylamine::CHEMBL332017 Mu-type opioid receptor Cavia cutleri 1.8 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092176&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 12994686 103990366 CHEMBL332017 ZINC13493411 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121682 C[C@H]1C2Cc3ccc(Nc4ccncc4)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C23H29N3/c1-16-22-13-18-5-6-20(25-19-7-10-24-11-8-19)14-21(18)23(16,2)9-12-26(22)15-17-3-4-17/h5-8,10-11,14,16-17,22H,3-4,9,12-13,15H2,1-2H3,(H,24,25)/t16-,22?,23-/m0/s1 KSTUAFOFLCIWRV-GDTQQENISA-N 50123987 (3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-pyridin-4-yl-amine::CHEMBL168409 Mu-type opioid receptor Cavia cutleri 18 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123987 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123987&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44381048 104016354 CHEMBL168409 ZINC27980087 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121697 C[C@@H]1[C@@H]2Cc3ccc(N)cc3[C@]1(C)CCN2CC1CC1 InChI=1S/C18H26N2/c1-12-17-9-14-5-6-15(19)10-16(14)18(12,2)7-8-20(17)11-13-3-4-13/h5-6,10,12-13,17H,3-4,7-9,11,19H2,1-2H3/t12-,17+,18-/m1/s1 STNPURITMRUHGJ-OCBCSQNSSA-N 50124000 3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ylamine::CHEMBL2368320 Mu-type opioid receptor Cavia cutleri 780 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124000&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73351424 104016367 CHEMBL2368320 ZINC13493409 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121698 C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)N(C)Cc1ccccc1 InChI=1S/C26H34N2/c1-19-25-15-22-11-12-23(27(3)17-20-7-5-4-6-8-20)16-24(22)26(19,2)13-14-28(25)18-21-9-10-21/h4-8,11-12,16,19,21,25H,9-10,13-15,17-18H2,1-3H3/t19-,25?,26-/m0/s1 OHQXZYAOUKKRAK-JKEZHHNBSA-N 50085030 Benzyl-((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-methyl-amine::Benzyl-(3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-methyl-amine::CHEMBL293951 Mu-type opioid receptor Cavia cutleri 56 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085030&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44298201 103984513 CHEMBL293951 ZINC29548653 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121699 C[C@H]1C2N(CC3CC3)CC[C@]1(C)c1cc(O)ccc1C2=O InChI=1S/C18H23NO2/c1-11-16-17(21)14-6-5-13(20)9-15(14)18(11,2)7-8-19(16)10-12-3-4-12/h5-6,9,11-12,16,20H,3-4,7-8,10H2,1-2H3/t11-,16?,18-/m0/s1 HQBZLVPZOGIAIQ-GQWBRKQSSA-N 50123985 3-Cyclopropylmethyl-8-hydroxy-6,11-dimethyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::CHEMBL354172 Mu-type opioid receptor Cavia cutleri 3.3 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123985 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123985&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380980 104016352 CHEMBL354172 ZINC27987349 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121700 COc1ccc(CNc2ccc3CC4[C@H](C)[C@](C)(CCN4CC4CC4)c3c2)cc1 InChI=1S/C26H34N2O/c1-18-25-14-21-8-9-22(27-16-19-6-10-23(29-3)11-7-19)15-24(21)26(18,2)12-13-28(25)17-20-4-5-20/h6-11,15,18,20,25,27H,4-5,12-14,16-17H2,1-3H3/t18-,25?,26-/m0/s1 WHIHGNHXGKVNNM-XLXODUMSSA-N 50124003 (3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-(4-methoxy-benzyl)-amine::CHEMBL168913 Mu-type opioid receptor Cavia cutleri 7.8 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124003 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124003&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44381041 104016370 CHEMBL168913 ZINC27900997 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121701 C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)N1CCN(C)CC1 InChI=1S/C23H35N3/c1-17-22-14-19-6-7-20(25-12-10-24(3)11-13-25)15-21(19)23(17,2)8-9-26(22)16-18-4-5-18/h6-7,15,17-18,22H,4-5,8-14,16H2,1-3H3/t17-,22?,23-/m0/s1 DQRUYAPFAYHFFI-XHLMSTEBSA-N 50085026 (6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-8-(4-methyl-piperazin-1-yl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::3-Cyclopropylmethyl-6,11-dimethyl-8-(4-methyl-piperazin-1-yl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::CHEMBL55392 Mu-type opioid receptor Cavia cutleri 21 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085026&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44298202 103984509 CHEMBL55392 ZINC29548656 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121702 C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)N1CCOCC1 InChI=1S/C22H32N2O/c1-16-21-13-18-5-6-19(23-9-11-25-12-10-23)14-20(18)22(16,2)7-8-24(21)15-17-3-4-17/h5-6,14,16-17,21H,3-4,7-13,15H2,1-2H3/t16-,21?,22-/m0/s1 FCUBDHJZNYQBJC-URJRECBDSA-N 50085027 (6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-8-morpholin-4-yl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::3-Cyclopropylmethyl-6,11-dimethyl-8-morpholin-4-yl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::CHEMBL55248 Mu-type opioid receptor Cavia cutleri 650 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085027&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44298203 103984510 CHEMBL55248 ZINC29548924 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121704 C[C@H]1C2Cc3cc4c(cc3[C@@]1(C)CCN2CC1CC1)[nH]c1ccccc41 InChI=1S/C24H28N2/c1-15-23-12-17-11-19-18-5-3-4-6-21(18)25-22(19)13-20(17)24(15,2)9-10-26(23)14-16-7-8-16/h3-6,11,13,15-16,23,25H,7-10,12,14H2,1-2H3/t15-,23?,24-/m0/s1 KOODECODLWKEAK-BERSIMOUSA-N 50123991 17-cyclopropylmethyl-1,20-dimethyl-(1S,20R)-5,17-diazapentacyclo[14.3.1.02,14.04,12.06,11]icosa-2(14),3,6(11),7,9,12-hexaene::CHEMBL352365 Mu-type opioid receptor Cavia cutleri 22 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123991 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123991&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44381243 104016358 CHEMBL352365 ZINC27900295 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121706 C[C@H]1C2Cc3cc4cc[nH]c4cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C20H26N2/c1-13-19-10-16-9-15-5-7-21-18(15)11-17(16)20(13,2)6-8-22(19)12-14-3-4-14/h5,7,9,11,13-14,19,21H,3-4,6,8,10,12H2,1-2H3/t13-,19?,20-/m0/s1 FNKKDOCWGPFFMB-RIHNOLBDSA-N 50124004 13-cyclopropylmethyl-1,16-dimethyl-(1S,16R)-5,13-diazatetracyclo[10.3.1.02,10.04,8]hexadeca-2(10),3,6,8-tetraene::CHEMBL170384 Mu-type opioid receptor Cavia cutleri 18 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124004 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124004&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44381244 104016371 CHEMBL170384 ZINC27900298 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121773 C[C@H]1[C@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CC1CC1 InChI=1S/C18H25NO/c1-12-17-9-14-5-6-15(20)10-16(14)18(12,2)7-8-19(17)11-13-3-4-13/h5-6,10,12-13,17,20H,3-4,7-9,11H2,1-2H3/t12-,17+,18+/m0/s1 YQYVFVRQLZMJKJ-JBBXEZCESA-N 50001023 (2R,6R,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL56585::Cyclazocine::US10231963, Table B.9::US10736890, Compound TABLE B.9::US11534436, Compound Table B.9::US9656961, Example 00126 Mu-type opioid receptor Cavia cutleri 0.100000 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001023&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3037926 103915556 CHEMBL56585 ZINC03830613 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121775 C[C@H]1C2Cc3ccc(Nc4cccnc4)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C23H29N3/c1-16-22-12-18-7-8-19(25-20-4-3-10-24-14-20)13-21(18)23(16,2)9-11-26(22)15-17-5-6-17/h3-4,7-8,10,13-14,16-17,22,25H,5-6,9,11-12,15H2,1-2H3/t16-,22?,23-/m0/s1 OHSQUTOUXRPUSB-GDTQQENISA-N 50123997 (3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-pyridin-3-yl-amine::CHEMBL422563 Mu-type opioid receptor Cavia cutleri 0.640000 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123997 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123997&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44381112 104016364 CHEMBL422563 ZINC27985105 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50121776 CNc1ccc2CC3[C@H](C)[C@](C)(CCN3CC3CC3)c2c1 InChI=1S/C19H28N2/c1-13-18-10-15-6-7-16(20-3)11-17(15)19(13,2)8-9-21(18)12-14-4-5-14/h6-7,11,13-14,18,20H,4-5,8-10,12H2,1-3H3/t13-,18?,19-/m0/s1 ZYIYQDGBJHOITC-IMWIMMFESA-N 50085029 ((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-methyl-amine::(3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-methyl-amine::(3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-methyl-amine.2HCl.C2H6O.H2O::CHEMBL291751 Mu-type opioid receptor Cavia cutleri 13 ChEMBL 10.1021/jm020429w 10.7270/Q2Z31Z09 12593663 Wentland, MP; Ye, Y; Cioffi, CL; Lou, R; Zhou, Q; Xu, G; Duan, W; Dehnhardt, CM; Sun, X; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085029&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44298233 103984512 CHEMBL291751 ZINC29553596 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50124394 CN(C)C(=O)C(CCN1CCC(O)(CC1)c1ccc(Cl)cc1)(c1ccccc1)c1ccccc1 InChI=1S/C29H33ClN2O2/c1-31(2)27(33)29(24-9-5-3-6-10-24,25-11-7-4-8-12-25)19-22-32-20-17-28(34,18-21-32)23-13-15-26(30)16-14-23/h3-16,34H,17-22H2,1-2H3 RDOIQAHITMMDAJ-UHFFFAOYSA-N 50017698 4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N,N-dimethyl-2,2-diphenylbutanamide::4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-N,N-dimethyl-2,2-diphenyl-butyramide::4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-N,N-dimethyl-2,2-diphenyl-butyramide(loperamide)::CHEMBL841::Imodium::LOPERAMIDE::LOPERAMIDE HYDROCHLORIDE::cid_71420::med.21724, Compound 184 Mu-type opioid receptor Cavia cutleri 58 ChEMBL 10.1021/jm030548r 10.7270/Q2H131GF 15456245 Breslin, HJ; Miskowski, TA; Rafferty, BM; Coutinho, SV; Palmer, JM; Wallace, NH; Schneider, CR; Kimball, ES; Zhang, SP; Li, J; Colburn, RW; Stone, DJ; Martinez, RP; He, W Johnson & Johnson Pharmaceutical Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017698&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3955 103928966 6532 CHEMBL841 DB00836 7215 C07080 ZINC00537928 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50124395 N[C@@H](Cc1ccc(O)cc1)C(=O)N1Cc2ccccc2C[C@H]1c1nc2ccccc2[nH]1 InChI=1S/C25H24N4O2/c26-20(13-16-9-11-19(30)12-10-16)25(31)29-15-18-6-2-1-5-17(18)14-23(29)24-27-21-7-3-4-8-22(21)28-24/h1-12,20,23,30H,13-15,26H2,(H,27,28)/t20-,23-/m0/s1 UUNVLVIBWMJAMY-REWPJTCUSA-N 50154040 2-Amino-1-[3-(1H-benzoimidazol-2-yl)-3,4-dihydro-1H-isoquinolin-2-yl]-3-(4-hydroxy-phenyl)-propan-1-one::CHEMBL362514 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm030548r 10.7270/Q2H131GF 15456245 Breslin, HJ; Miskowski, TA; Rafferty, BM; Coutinho, SV; Palmer, JM; Wallace, NH; Schneider, CR; Kimball, ES; Zhang, SP; Li, J; Colburn, RW; Stone, DJ; Martinez, RP; He, W Johnson & Johnson Pharmaceutical Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50154040 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50154040&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11235302 104041788 CHEMBL362514 ZINC13583524 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50124416 N[C@@H](Cc1ccc(O)cc1)C(=O)N1Cc2ccccc2C[C@H]1c1nc(c(Br)[nH]1)-c1ccccc1 InChI=1S/C27H25BrN4O2/c28-25-24(18-6-2-1-3-7-18)30-26(31-25)23-15-19-8-4-5-9-20(19)16-32(23)27(34)22(29)14-17-10-12-21(33)13-11-17/h1-13,22-23,33H,14-16,29H2,(H,30,31)/t22-,23-/m0/s1 ZOOZSJDDSQWMQP-GOTSBHOMSA-N 50154039 2-Amino-1-[3-(5-bromo-4-phenyl-1H-imidazol-2-yl)-3,4-dihydro-1H-isoquinolin-2-yl]-3-(4-hydroxy-phenyl)-propan-1-one::CHEMBL408680 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm030548r 10.7270/Q2H131GF 15456245 Breslin, HJ; Miskowski, TA; Rafferty, BM; Coutinho, SV; Palmer, JM; Wallace, NH; Schneider, CR; Kimball, ES; Zhang, SP; Li, J; Colburn, RW; Stone, DJ; Martinez, RP; He, W Johnson & Johnson Pharmaceutical Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50154039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50154039&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11375776 104041787 CHEMBL408680 ZINC13583517 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50124418 Cc1[nH]c(nc1-c1ccccc1)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C28H28N4O2/c1-18-26(20-7-3-2-4-8-20)31-27(30-18)25-16-21-9-5-6-10-22(21)17-32(25)28(34)24(29)15-19-11-13-23(33)14-12-19/h2-14,24-25,33H,15-17,29H2,1H3,(H,30,31)/t24-,25-/m0/s1 PHZQHCMEUDDSTI-DQEYMECFSA-N 50154035 (S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-3-(5-methyl-4-phenyl-1H-imidazol-2-yl)-3,4-dihydroisoquinolin-2(1H)-yl)propan-1-one::2-Amino-3-(4-hydroxy-phenyl)-1-[3-(5-methyl-4-phenyl-1H-imidazol-2-yl)-3,4-dihydro-1H-isoquinolin-2-yl]-propan-1-one::CHEMBL361033 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm030548r 10.7270/Q2H131GF 15456245 Breslin, HJ; Miskowski, TA; Rafferty, BM; Coutinho, SV; Palmer, JM; Wallace, NH; Schneider, CR; Kimball, ES; Zhang, SP; Li, J; Colburn, RW; Stone, DJ; Martinez, RP; He, W Johnson & Johnson Pharmaceutical Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50154035 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50154035&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11213149 104041783 CHEMBL361033 ZINC13583514 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50124420 Cc1[nH]c(nc1-c1ccccc1)[C@@H]1CCCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C24H28N4O2/c1-16-22(18-7-3-2-4-8-18)27-23(26-16)21-9-5-6-14-28(21)24(30)20(25)15-17-10-12-19(29)13-11-17/h2-4,7-8,10-13,20-21,29H,5-6,9,14-15,25H2,1H3,(H,26,27)/t20-,21-/m0/s1 MKNJLSBSRYKNIQ-SFTDATJTSA-N 50154041 (S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-2-(5-methyl-4-phenyl-1H-imidazol-2-yl)piperidin-1-yl)propan-1-one::2-Amino-3-(4-hydroxy-phenyl)-1-[2-(5-methyl-4-phenyl-1H-imidazol-2-yl)-piperidin-1-yl]-propan-1-one::CHEMBL366311 Mu-type opioid receptor Cavia cutleri 153 ChEMBL 10.1021/jm030548r 10.7270/Q2H131GF 15456245 Breslin, HJ; Miskowski, TA; Rafferty, BM; Coutinho, SV; Palmer, JM; Wallace, NH; Schneider, CR; Kimball, ES; Zhang, SP; Li, J; Colburn, RW; Stone, DJ; Martinez, RP; He, W Johnson & Johnson Pharmaceutical Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50154041 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50154041&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11361718 104041789 CHEMBL366311 ZINC13583526 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50124423 N[C@@H](Cc1ccc(O)cc1)C(=O)N1Cc2ccccc2C[C@H]1c1nc(c[nH]1)-c1ccccc1 InChI=1S/C27H26N4O2/c28-23(14-18-10-12-22(32)13-11-18)27(33)31-17-21-9-5-4-8-20(21)15-25(31)26-29-16-24(30-26)19-6-2-1-3-7-19/h1-13,16,23,25,32H,14-15,17,28H2,(H,29,30)/t23-,25-/m0/s1 SWZLGDBFWBZXTL-ZCYQVOJMSA-N 50154036 (S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-3-(4-phenyl-1H-imidazol-2-yl)-3,4-dihydroisoquinolin-2(1H)-yl)propan-1-one::2-Amino-3-(4-hydroxy-phenyl)-1-[3-(4-phenyl-1H-imidazol-2-yl)-3,4-dihydro-1H-isoquinolin-2-yl]-propan-1-one::CHEMBL361274 Mu-type opioid receptor Cavia cutleri 2400 ChEMBL 10.1021/jm030548r 10.7270/Q2H131GF 15456245 Breslin, HJ; Miskowski, TA; Rafferty, BM; Coutinho, SV; Palmer, JM; Wallace, NH; Schneider, CR; Kimball, ES; Zhang, SP; Li, J; Colburn, RW; Stone, DJ; Martinez, RP; He, W Johnson & Johnson Pharmaceutical Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50154036 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50154036&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9932852 104041784 CHEMBL361274 ZINC36216109 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50124424 N[C@@H](Cc1ccc(O)cc1)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCCc1ccccc1 InChI=1S/C27H29N3O3/c28-24(16-20-10-12-23(31)13-11-20)27(33)30-18-22-9-5-4-8-21(22)17-25(30)26(32)29-15-14-19-6-2-1-3-7-19/h1-13,24-25,31H,14-18,28H2,(H,29,32)/t24-,25-/m0/s1 MEWPEMCLAQRYBC-DQEYMECFSA-N 50154042 2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid phenethyl-amide::CHEMBL188558 Mu-type opioid receptor Cavia cutleri 2120 ChEMBL 10.1021/jm030548r 10.7270/Q2H131GF 15456245 Breslin, HJ; Miskowski, TA; Rafferty, BM; Coutinho, SV; Palmer, JM; Wallace, NH; Schneider, CR; Kimball, ES; Zhang, SP; Li, J; Colburn, RW; Stone, DJ; Martinez, RP; He, W Johnson & Johnson Pharmaceutical Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50154042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50154042&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44396503 104041790 CHEMBL188558 ZINC13583509 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50124426 Cc1[nH]c(nc1-c1ccccc1)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C23H26N4O2/c1-15-21(17-6-3-2-4-7-17)26-22(25-15)20-8-5-13-27(20)23(29)19(24)14-16-9-11-18(28)12-10-16/h2-4,6-7,9-12,19-20,28H,5,8,13-14,24H2,1H3,(H,25,26)/t19-,20-/m0/s1 WTLPGZMNWBXIHT-PMACEKPBSA-N 50154037 2-Amino-3-(4-hydroxy-phenyl)-1-[2-(5-methyl-4-phenyl-1H-imidazol-2-yl)-pyrrolidin-1-yl]-propan-1-one::CHEMBL186527 Mu-type opioid receptor Cavia cutleri 1300 ChEMBL 10.1021/jm030548r 10.7270/Q2H131GF 15456245 Breslin, HJ; Miskowski, TA; Rafferty, BM; Coutinho, SV; Palmer, JM; Wallace, NH; Schneider, CR; Kimball, ES; Zhang, SP; Li, J; Colburn, RW; Stone, DJ; Martinez, RP; He, W Johnson & Johnson Pharmaceutical Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50154037 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50154037&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11417908 104041785 CHEMBL186527 ZINC13583528 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50148852 CC(C)(C)c1ccc(cc1)C(C1CCN(Cc2ccccc2)CC1)c1cccc(O)c1 InChI=1S/C29H35NO/c1-29(2,3)26-14-12-23(13-15-26)28(25-10-7-11-27(31)20-25)24-16-18-30(19-17-24)21-22-8-5-4-6-9-22/h4-15,20,24,28,31H,16-19,21H2,1-3H3 ZDRADNOKATWGBW-UHFFFAOYSA-N 50084129 3-[(1-Benzyl-piperidin-4-yl)-(4-tert-butyl-phenyl)-methyl]-phenol::CHEMBL151341 Mu-type opioid receptor Cavia cutleri 15600 ChEMBL 10.1021/jm990337f 10.7270/Q23777XM 10639279 Alfaro-Lopez, J; Okayama, T; Hosohata, K; Davis, P; Porreca, F; Yamamura, HI; Hruby, VJ The University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50084129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50084129&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10573793 103983713 CHEMBL151341 ZINC13803308 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50154859 CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@]1(N)CCc2cc(O)ccc2C1)[C@@H](C)CC)C(=O)NCC(N)=O InChI=1S/C42H60N8O10/c1-6-23(3)34(39(58)45-22-32(43)52)50-40(59)35(24(4)7-2)49-37(56)30(15-16-33(53)54)47-38(57)31(19-26-11-9-8-10-12-26)48-36(55)25(5)46-41(60)42(44)18-17-27-20-29(51)14-13-28(27)21-42/h8-14,20,23-25,30-31,34-35,51H,6-7,15-19,21-22,44H2,1-5H3,(H2,43,52)(H,45,58)(H,46,60)(H,47,57)(H,48,55)(H,49,56)(H,50,59)(H,53,54)/t23-,24-,25-,30-,31-,34-,35-,42-/m0/s1 CGXNXLAZEVZEJK-JQESVBDTSA-N 50087063 4-(2-{2-[(2-Amino-6-hydroxy-1,2,3,4-tetrahydro-naphthalene-2-carbonyl)-amino]-propionylamino}-3-phenyl-propionylamino)-4-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-butylcarbamoyl]-2-methyl-butylcarbamoyl}-butyric acid::CHEMBL280848 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm9911534 10.7270/Q2MS3S0S 10753473 Darula, Z; Kover, KE; Monory, K; Borsodi, A; Mako, E; Ronai, A; Tourwe, D; Peter, A; Toth, G Hungarian Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087063 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087063&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44277598 103986150 CHEMBL280848 ZINC95608329 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50154863 CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@@]1(N)CCc2cc(O)ccc2C1)[C@@H](C)CC)C(=O)NCC(N)=O InChI=1S/C42H60N8O10/c1-6-23(3)34(39(58)45-22-32(43)52)50-40(59)35(24(4)7-2)49-37(56)30(15-16-33(53)54)47-38(57)31(19-26-11-9-8-10-12-26)48-36(55)25(5)46-41(60)42(44)18-17-27-20-29(51)14-13-28(27)21-42/h8-14,20,23-25,30-31,34-35,51H,6-7,15-19,21-22,44H2,1-5H3,(H2,43,52)(H,45,58)(H,46,60)(H,47,57)(H,48,55)(H,49,56)(H,50,59)(H,53,54)/t23-,24-,25-,30-,31-,34-,35-,42+/m0/s1 CGXNXLAZEVZEJK-VFGMNGPMSA-N 50087064 4-(2-{2-[(2-Amino-6-hydroxy-1,2,3,4-tetrahydro-naphthalene-2-carbonyl)-amino]-propionylamino}-3-phenyl-propionylamino)-4-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-butylcarbamoyl]-2-methyl-butylcarbamoyl}-butyric acid::CHEMBL283009 Mu-type opioid receptor Cavia cutleri 5129.0 ChEMBL 10.1021/jm9911534 10.7270/Q2MS3S0S 10753473 Darula, Z; Kover, KE; Monory, K; Borsodi, A; Mako, E; Ronai, A; Tourwe, D; Peter, A; Toth, G Hungarian Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087064&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44277651 103986151 CHEMBL283009 ZINC95542321 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50164414 CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23-,24-/m0/s1 MCMMCRYPQBNCPH-DVKRWUGUSA-N 50001683 13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid::7-Benzyl-10-{[3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL294616::DPDPE Mu-type opioid receptor Cavia cutleri 2720 ChEMBL 10.1021/jm100157m 10.7270/Q21N81BD 20617791 Yamamoto, T; Nair, P; Jacobsen, NE; Kulkarni, V; Davis, P; Ma, SW; Navratilova, E; Yamamura, HI; Vanderah, TW; Porreca, F; Lai, J; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001683&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299404 103916113 CHEMBL294616 ZINC27520031 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015540 CCNC(=O)C(CC(C)C)NC(=O)C(CCC[N-]C(N)=[NH2+])N(C)C(=O)C(CCC[N-]C(N)=[NH2+])NC(=O)C(CC(C)C)NC(=O)C(Cc1ccc(cc1)[N+]([O-])=O)NC(=O)CNC(=O)CNC(=O)C(Cc1ccc(O)cc1)NC InChI=1S/C50H80N16O11/c1-8-56-44(71)37(23-29(2)3)64-47(74)40(12-10-22-58-50(53)54)65(7)48(75)35(11-9-21-57-49(51)52)62-45(72)38(24-30(4)5)63-46(73)39(26-31-13-17-33(18-14-31)66(76)77)61-42(69)28-59-41(68)27-60-43(70)36(55-6)25-32-15-19-34(67)20-16-32/h13-20,29-30,35-40,55H,8-12,21-28H2,1-7H3,(H16,51,52,53,54,56,57,58,59,60,61,62,63,64,67,68,69,70,71,72,73,74) WERDBVWQNIXFQM-UHFFFAOYSA-N 50010545 2-{5-Guanidino-2-[(5-guanidino-2-{2-[2-(2-{2-[3-(4-hydroxy-phenyl)-2-methylamino-propionylamino]-acetylamino}-acetylamino)-3-(4-nitro-phenyl)-propionylamino]-4-methyl-pentanoylamino}-pentanoyl)-methyl-amino]-pentanoylamino}-4-methyl-pentanoic acidN-ethyl amide::CHEMBL415410 Mu-type opioid receptor Cavia cutleri 1.7 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010545 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010545&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14015071 103923321 CHEMBL415410 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50175150 C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)C#N InChI=1S/C19H24N2/c1-13-18-10-16-6-5-15(11-20)9-17(16)19(13,2)7-8-21(18)12-14-3-4-14/h5-6,9,13-14,18H,3-4,7-8,10,12H2,1-2H3/t13-,18?,19-/m0/s1 COAUQMNDFOCIAR-IMWIMMFESA-N 50097581 (6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carbonitrile::CHEMBL154255 Mu-type opioid receptor Cavia cutleri 540 ChEMBL 10.1016/s0960-894x(01)00014-2 10.7270/Q2542MVZ 11266156 Wentland, MP; Lou, R; Ye, Y; Cohen, DJ; Richardson, GP; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097581 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097581&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44371894 103994789 CHEMBL154255 ZINC27654506 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50175151 C[C@@H]1[C@@H]2Cc3ccc(cc3[C@]1(C)CCN2CC1CC1)C(N)=O InChI=1S/C19H26N2O/c1-12-17-10-14-5-6-15(18(20)22)9-16(14)19(12,2)7-8-21(17)11-13-3-4-13/h5-6,9,12-13,17H,3-4,7-8,10-11H2,1-2H3,(H2,20,22)/t12-,17+,19-/m1/s1 FAVQVALXVLMHLE-JLBUNGTFSA-N 50097578 (6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid amide::CHEMBL157313 Mu-type opioid receptor Cavia cutleri 63 ChEMBL 10.1016/s0960-894x(01)00014-2 10.7270/Q2542MVZ 11266156 Wentland, MP; Lou, R; Ye, Y; Cohen, DJ; Richardson, GP; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097578&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44371907 103994786 CHEMBL157313 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50175154 CC[C@]12CCN(CC3CC3)C([C@@H]1C)C(=O)c1ccc(O)cc21 InChI=1S/C19H25NO2/c1-3-19-8-9-20(11-13-4-5-13)17(12(19)2)18(22)15-7-6-14(21)10-16(15)19/h6-7,10,12-13,17,21H,3-5,8-9,11H2,1-2H3/t12-,17?,19-/m0/s1 SEJUQQOPVAUETF-BKBNBNODSA-N 50000091 (6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::(6S,11R)-3-Cyclopropylmethyl-9-hydroxy-6,11-dimethyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one (ethylketocyclazocine)::3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one(Ethylketazocine, EKC)::CHEMBL279968::EKC::EKC(-) Mu-type opioid receptor Cavia cutleri 0.780000 ChEMBL 10.1016/s0960-894x(01)00014-2 10.7270/Q2542MVZ 11266156 Wentland, MP; Lou, R; Ye, Y; Cohen, DJ; Richardson, GP; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000091&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44273397 103914788 CHEMBL279968 ZINC00967957 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50175157 C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)C(=O)N(C)C InChI=1S/C21H30N2O/c1-14-19-12-16-7-8-17(20(24)22(3)4)11-18(16)21(14,2)9-10-23(19)13-15-5-6-15/h7-8,11,14-15,19H,5-6,9-10,12-13H2,1-4H3/t14-,19?,21-/m0/s1 UXAUEPMAMFGTRV-VVHKJBIHSA-N 50097583 (6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid dimethylamide::CHEMBL346813 Mu-type opioid receptor Cavia cutleri 3000 ChEMBL 10.1016/s0960-894x(01)00014-2 10.7270/Q2542MVZ 11266156 Wentland, MP; Lou, R; Ye, Y; Cohen, DJ; Richardson, GP; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097583 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097583&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44371877 103994791 CHEMBL346813 ZINC27708515 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50175161 C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)C(N)=O InChI=1S/C19H26N2O/c1-12-17-10-14-5-6-15(18(20)22)9-16(14)19(12,2)7-8-21(17)11-13-3-4-13/h5-6,9,12-13,17H,3-4,7-8,10-11H2,1-2H3,(H2,20,22)/t12-,17?,19-/m0/s1 FAVQVALXVLMHLE-BKBNBNODSA-N 50097579 (6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid amide::8-CAC::8-carboxamidocyclazocine::CHEMBL58646::US9656961, Example 00157 Mu-type opioid receptor Cavia cutleri 0.410000 ChEMBL 10.1016/s0960-894x(01)00014-2 10.7270/Q2542MVZ 11266156 Wentland, MP; Lou, R; Ye, Y; Cohen, DJ; Richardson, GP; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097579 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097579&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10086063 103994787 CHEMBL58646 ZINC29411253 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50175163 C[C@H]1[C@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CC1CC1 InChI=1S/C18H25NO/c1-12-17-9-14-5-6-15(20)10-16(14)18(12,2)7-8-19(17)11-13-3-4-13/h5-6,10,12-13,17,20H,3-4,7-9,11H2,1-2H3/t12-,17+,18+/m0/s1 YQYVFVRQLZMJKJ-JBBXEZCESA-N 50001023 (2R,6R,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL56585::Cyclazocine::US10231963, Table B.9::US10736890, Compound TABLE B.9::US11534436, Compound Table B.9::US9656961, Example 00126 Mu-type opioid receptor Cavia cutleri 0.100000 ChEMBL 10.1016/s0960-894x(01)00014-2 10.7270/Q2542MVZ 11266156 Wentland, MP; Lou, R; Ye, Y; Cohen, DJ; Richardson, GP; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001023&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3037926 103915556 CHEMBL56585 ZINC03830613 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50175165 C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)C(O)=O InChI=1S/C19H25NO2/c1-12-17-10-14-5-6-15(18(21)22)9-16(14)19(12,2)7-8-20(17)11-13-3-4-13/h5-6,9,12-13,17H,3-4,7-8,10-11H2,1-2H3,(H,21,22)/t12-,17?,19-/m0/s1 SBHTVJXZVQWEPY-BKBNBNODSA-N 50097584 (6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid::CHEMBL160677 Mu-type opioid receptor Cavia cutleri 58 ChEMBL 10.1016/s0960-894x(01)00014-2 10.7270/Q2542MVZ 11266156 Wentland, MP; Lou, R; Ye, Y; Cohen, DJ; Richardson, GP; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097584 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097584&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44371817 103994792 CHEMBL160677 ZINC27720350 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50175166 COC(=O)c1ccc2CC3[C@H](C)[C@](C)(CCN3CC3CC3)c2c1 InChI=1S/C20H27NO2/c1-13-18-11-15-6-7-16(19(22)23-3)10-17(15)20(13,2)8-9-21(18)12-14-4-5-14/h6-7,10,13-14,18H,4-5,8-9,11-12H2,1-3H3/t13-,18?,20-/m0/s1 ZOMNBLOBZKEMJP-BXBUHSQYSA-N 50097582 (6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid methyl ester::CHEMBL160924 Mu-type opioid receptor Cavia cutleri 45 ChEMBL 10.1016/s0960-894x(01)00014-2 10.7270/Q2542MVZ 11266156 Wentland, MP; Lou, R; Ye, Y; Cohen, DJ; Richardson, GP; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097582 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097582&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44371818 103994790 CHEMBL160924 ZINC27720361 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50175168 C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)C(=O)Nc1ccccc1 InChI=1S/C25H30N2O/c1-17-23-15-19-10-11-20(24(28)26-21-6-4-3-5-7-21)14-22(19)25(17,2)12-13-27(23)16-18-8-9-18/h3-7,10-11,14,17-18,23H,8-9,12-13,15-16H2,1-2H3,(H,26,28)/t17-,23?,25-/m0/s1 OVRRAJPGDYSIJW-DQNHKJGCSA-N 50097577 (6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid phenylamide::3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid phenylamide::CHEMBL293103 Mu-type opioid receptor Cavia cutleri 740 ChEMBL 10.1016/s0960-894x(01)00014-2 10.7270/Q2542MVZ 11266156 Wentland, MP; Lou, R; Ye, Y; Cohen, DJ; Richardson, GP; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097577&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299841 103994785 CHEMBL293103 ZINC29556310 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50175171 CNC(=O)c1ccc2CC3[C@H](C)[C@](C)(CCN3CC3CC3)c2c1 InChI=1S/C20H28N2O/c1-13-18-11-15-6-7-16(19(23)21-3)10-17(15)20(13,2)8-9-22(18)12-14-4-5-14/h6-7,10,13-14,18H,4-5,8-9,11-12H2,1-3H3,(H,21,23)/t13-,18?,20-/m0/s1 RHYWXBNKDLNMDH-BXBUHSQYSA-N 50097585 (6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid methylamide::CHEMBL157301 Mu-type opioid receptor Cavia cutleri 24 ChEMBL 10.1016/s0960-894x(01)00014-2 10.7270/Q2542MVZ 11266156 Wentland, MP; Lou, R; Ye, Y; Cohen, DJ; Richardson, GP; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097585 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097585&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44371878 103994793 CHEMBL157301 ZINC27708519 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50175176 CC[C@]12CCN(CC3CC3)C([C@@H]1C)C(=O)c1ccc(cc21)C(N)=O InChI=1S/C20H26N2O2/c1-3-20-8-9-22(11-13-4-5-13)17(12(20)2)18(23)15-7-6-14(19(21)24)10-16(15)20/h6-7,10,12-13,17H,3-5,8-9,11H2,1-2H3,(H2,21,24)/t12-,17?,20-/m0/s1 NBEPKKBOGWVFFT-HQWCKNPASA-N 50097586 (6S,11R)-3-Cyclopropylmethyl-6-ethyl-11-methyl-1-oxo-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid amide::3-cyclopropylmethyl-6-ethyl-11-methyl-1-oxo-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid amide::CHEMBL60869 Mu-type opioid receptor Cavia cutleri 1.2 ChEMBL 10.1016/s0960-894x(01)00014-2 10.7270/Q2542MVZ 11266156 Wentland, MP; Lou, R; Ye, Y; Cohen, DJ; Richardson, GP; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097586 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097586&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300146 103994794 CHEMBL60869 ZINC29563889 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50175177 C[C@H]1[C@H]2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)C(N)=O InChI=1S/C19H26N2O/c1-12-17-10-14-5-6-15(18(20)22)9-16(14)19(12,2)7-8-21(17)11-13-3-4-13/h5-6,9,12-13,17H,3-4,7-8,10-11H2,1-2H3,(H2,20,22)/t12-,17+,19-/m0/s1 FAVQVALXVLMHLE-WILYLXEWSA-N 50097580 (6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid amide::CHEMBL2368218 Mu-type opioid receptor Cavia cutleri 0.170000 ChEMBL 10.1016/s0960-894x(01)00014-2 10.7270/Q2542MVZ 11266156 Wentland, MP; Lou, R; Ye, Y; Cohen, DJ; Richardson, GP; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097580 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097580&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 12994684 103994788 CHEMBL2368218 ZINC13490115 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50204249 C[C@H]1CN(C\C=C\c2ccccc2Cl)CC[C@@]1(C)c1cccc(O)c1 InChI=1S/C22H26ClNO/c1-17-16-24(13-6-8-18-7-3-4-11-21(18)23)14-12-22(17,2)19-9-5-10-20(25)15-19/h3-11,15,17,25H,12-14,16H2,1-2H3/b8-6+/t17-,22+/m0/s1 RRGWRLNJBLFYOG-KISUKSLOSA-N 50064518 3-{(3R,4R)-1-[(E)-3-(2-Chloro-phenyl)-allyl]-3,4-dimethyl-piperidin-4-yl}-phenol::3-{1-[3-(2-Chloro-phenyl)-allyl]-3,4-dimethyl-piperidin-4-yl}-phenol::CHEMBL50594::RTI-5989-23 Mu-type opioid receptor Cavia cutleri 1.1 ChEMBL 10.1021/jm030092d 10.7270/Q2FF3T3J 12723940 Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064518&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10808145 103959535 CHEMBL50594 ZINC13779626 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50204257 CC(C)[C@@H](CN1CC[C@](C)([C@@H](C)C1)c1cccc(O)c1)NC(=O)CCc1ccc(O)cc1 InChI=1S/C27H38N2O3/c1-19(2)25(28-26(32)13-10-21-8-11-23(30)12-9-21)18-29-15-14-27(4,20(3)17-29)22-6-5-7-24(31)16-22/h5-9,11-12,16,19-20,25,30-31H,10,13-15,17-18H2,1-4H3,(H,28,32)/t20-,25+,27+/m0/s1 BOXRUELCJUEBJH-FBQMUFCQSA-N 50102710 3-(4-Hydroxy-phenyl)-N-{(S)-1-[(3R,4R)-4-(3-hydroxy-phenyl)-3,4-dimethyl-piperidin-1-ylmethyl]-2-methyl-propyl}-propionamide::3-(4-Hydroxy-phenyl)-N-{1-[4-(3-hydroxy-phenyl)-3,4-dimethyl-piperidin-1-ylmethyl]-2-methyl-propyl}-propionamide::CHEMBL10986 Mu-type opioid receptor Cavia cutleri 393 ChEMBL 10.1021/jm030092d 10.7270/Q2FF3T3J 12723940 Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102710 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102710&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9804952 103999146 CHEMBL10986 ZINC04424128 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50202182 CCO[C@H](C)[C@@H]1C[C@]23C=C[C@]1(OC)[C@H]1Oc4c5c(C[C@H]2N(C)CCC315)ccc4O InChI=1S/C24H31NO4/c1-5-28-14(2)16-13-22-8-9-24(16,27-4)21-23(22)10-11-25(3)18(22)12-15-6-7-17(26)20(29-21)19(15)23/h6-9,14,16,18,21,26H,5,10-13H2,1-4H3/t14-,16+,18-,21+,22-,23?,24-/m1/s1 YLGFGFSODXCCQV-LJAXJJGUSA-N 50026890 CHEMBL2113670 Mu-type opioid receptor Cavia cutleri 0.500000 ChEMBL 10.1021/jm990951r 10.7270/Q2J67HN1 10794701 Coop, A; Norton, CL; Berzetei-Gurske, I; Burnside, J; Toll, L; Husbands, SM; Lewis, JW University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026890&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71461673 103936474 CHEMBL2113670 ZINC53059282 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50202186 CCO[C@@H](C)[C@@H]1CC23C=C[C@]1(OC)[C@H]1Oc4c5c(CC2N(C)CCC315)ccc4O InChI=1S/C24H31NO4/c1-5-28-14(2)16-13-22-8-9-24(16,27-4)21-23(22)10-11-25(3)18(22)12-15-6-7-17(26)20(29-21)19(15)23/h6-9,14,16,18,21,26H,5,10-13H2,1-4H3/t14-,16-,18?,21-,22?,23?,24+/m0/s1 YLGFGFSODXCCQV-RQHHNQSQSA-N 50369820 CHEMBL1169584 Mu-type opioid receptor Cavia cutleri 1 ChEMBL 10.1021/jm990951r 10.7270/Q2J67HN1 10794701 Coop, A; Norton, CL; Berzetei-Gurske, I; Burnside, J; Toll, L; Husbands, SM; Lewis, JW University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369820 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369820&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 49799968 160848922 CHEMBL1169584 ZINC36221092 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50202189 CCC[C@@](C)(O)[C@@H]1CC23C=C[C@]1(OC)[C@H]1Oc4c5c(CC2N(C)CCC315)ccc4O InChI=1S/C25H33NO4/c1-5-8-22(2,28)17-14-23-9-10-25(17,29-4)21-24(23)11-12-26(3)18(23)13-15-6-7-16(27)20(30-21)19(15)24/h6-7,9-10,17-18,21,27-28H,5,8,11-14H2,1-4H3/t17-,18?,21-,22+,23?,24?,25+/m0/s1 CAHCBJPUTCKATP-QQAQEGDCSA-N 50369821 CHEMBL1169585 Mu-type opioid receptor Cavia cutleri 1.5 ChEMBL 10.1021/jm990951r 10.7270/Q2J67HN1 10794701 Coop, A; Norton, CL; Berzetei-Gurske, I; Burnside, J; Toll, L; Husbands, SM; Lewis, JW University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369821 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369821&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 49799969 160848923 CHEMBL1169585 ZINC05649421 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50202190 CCC[C@](C)(O)[C@@H]1CC23C=C[C@]1(OC)[C@H]1Oc4c5c(CC2N(C)CCC315)ccc4O InChI=1S/C25H33NO4/c1-5-8-22(2,28)17-14-23-9-10-25(17,29-4)21-24(23)11-12-26(3)18(23)13-15-6-7-16(27)20(30-21)19(15)24/h6-7,9-10,17-18,21,27-28H,5,8,11-14H2,1-4H3/t17-,18?,21-,22-,23?,24?,25+/m0/s1 CAHCBJPUTCKATP-PRHRQKLRSA-N 50369822 CHEMBL1169580 Mu-type opioid receptor Cavia cutleri 0.500000 ChEMBL 10.1021/jm990951r 10.7270/Q2J67HN1 10794701 Coop, A; Norton, CL; Berzetei-Gurske, I; Burnside, J; Toll, L; Husbands, SM; Lewis, JW University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369822&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 49799964 160848924 CHEMBL1169580 ZINC05649042 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50204473 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C64H106N22O12/c1-6-37(4)51(60(97)82-46(21-14-30-76-64(72)73)61(98)86-31-15-22-49(86)59(96)79-43(52(67)89)18-10-11-27-65)85-56(93)45(20-13-29-75-63(70)71)80-55(92)44(19-12-28-74-62(68)69)81-57(94)47(32-36(2)3)84-58(95)48(34-39-16-8-7-9-17-39)83-53(90)38(5)78-50(88)35-77-54(91)42(66)33-40-23-25-41(87)26-24-40/h7-9,16-17,23-26,36-38,42-49,51,87H,6,10-15,18-22,27-35,65-66H2,1-5H3,(H2,67,89)(H,77,91)(H,78,88)(H,79,96)(H,80,92)(H,81,94)(H,82,97)(H,83,90)(H,84,95)(H,85,93)(H4,68,69,74)(H4,70,71,75)(H4,72,73,76)/t37-,38+,42-,43-,44-,45-,46-,47-,48-,49+,51-/m0/s1 AQXYHKIZMZEAGF-ZKSYIDMUSA-N 50090003 CHEMBL405190::Tyr-Gly-[D-Ala]-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-NH2::[D-Ala-3] Dynorphin A (1-11)-NH2H-Tyr-Gly-D-Ala-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-NH2 Mu-type opioid receptor Cavia cutleri 2.4 ChEMBL 10.1021/jm020125+ 10.7270/Q2NZ88CF 12747782 Schlechtingen, G; DeHaven, RN; Daubert, JD; Cassel, JA; Chung, NN; Schiller, PW; Taulane, JP; Goodman, M University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090003 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090003&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44306867 103988532 CHEMBL405190 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50205609 CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23-,24-/m0/s1 MCMMCRYPQBNCPH-DVKRWUGUSA-N 50001683 13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid::7-Benzyl-10-{[3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL294616::DPDPE Mu-type opioid receptor Cavia cutleri 11600 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001683&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299404 103916113 CHEMBL294616 ZINC27520031 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50204532 COCC[C@H]1CC2CN3CCc4c([nH]c5ccccc45)[C@](C2)(C13)C(=O)OC InChI=1S/C22H28N2O3/c1-26-10-8-15-11-14-12-22(21(25)27-2)19-17(7-9-24(13-14)20(15)22)16-5-3-4-6-18(16)23-19/h3-6,14-15,20,23H,7-13H2,1-2H3/t14?,15-,20?,22+/m0/s1 DTJQBBHYRQYDEG-YHIIEBRDSA-N 50129749 18-methoxycoronaridine Mu-type opioid receptor Cavia cutleri 1100 ChEMBL 10.1021/jm020562o 10.7270/Q23X87CQ 12801235 Kuehne, ME; He, L; Jokiel, PA; Pace, CJ; Fleck, MW; Maisonneuve, IM; Glick, SD; Bidlack, JM University of Vermont http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129749 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129749&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10248465 104021282 ZINC13522281 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50205668 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C)[C@@H](Cc1ccccc1)C(=O)NCCO InChI=1S/C26H35N5O6/c1-17(30-25(36)21(27)14-19-8-10-20(33)11-9-19)24(35)29-16-23(34)31(2)22(26(37)28-12-13-32)15-18-6-4-3-5-7-18/h3-11,17,21-22,32-33H,12-16,27H2,1-2H3,(H,28,37)(H,29,35)(H,30,36)/t17-,21+,22+/m1/s1 HPZJMUBDEAMBFI-WTNAPCKOSA-N 21015 (2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]-N-methylacetamido}-N-(2-hydroxyethyl)-3-phenylpropanamide::2-Ala-4-MePhe-5-Gly-Enkephalin::CHEMBL38874::D-Ala2-MePhe4-Met(0)5-enkephalin-ol::DAMGO::RX 783006::US11492374, ID 2::[3H]DAMGO::[tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephalin Mu-type opioid receptor Cavia cutleri 414 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21015&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5462471 49689088 CHEMBL38874 1647 C04080 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50205674 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@@H]3Cc1cc(cnc41)-c1ccc(Cl)c(Cl)c1)ccc5O InChI=1S/C26H22Cl2N2O2/c1-30-7-6-26-17-9-15-8-16(13-2-4-18(27)19(28)10-13)12-29-23(15)25(26)32-24-21(31)5-3-14(22(24)26)11-20(17)30/h2-5,8,10,12,17,20,25,31H,6-7,9,11H2,1H3/t17-,20?,25-,26-/m0/s1 UYVJZQXUZSFCBU-MTJLISISSA-N 50140909 6-(3,4-dichlorophenyl)-19-methyl-(2R,10R)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaen-13-ol Mu-type opioid receptor Cavia cutleri 1310 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140909 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140909&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44279826 104030445 ZINC13559701 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50205676 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@]3(O)Cc1cc(cnc41)-c1ccccc1)ccc5O InChI=1S/C26H24N2O3/c1-28-10-9-25-21-16-7-8-19(29)23(21)31-24(25)22-17(13-26(25,30)20(28)12-16)11-18(14-27-22)15-5-3-2-4-6-15/h2-8,11,14,20,24,29-30H,9-10,12-13H2,1H3/t20?,24-,25-,26+/m0/s1 MVNIBXTXVYCLEI-OOGIKFLQSA-N 50140903 19-methyl-6-phenyl-(2S,10R)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaene-2,13-diol Mu-type opioid receptor Cavia cutleri 660 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140903 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140903&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44279662 104030439 ZINC13559695 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50205677 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@]3(O)Cc1cccnc41)ccc5O InChI=1S/C20H20N2O3/c1-22-8-6-19-15-11-4-5-13(23)17(15)25-18(19)16-12(3-2-7-21-16)10-20(19,24)14(22)9-11/h2-5,7,14,18,23-24H,6,8-10H2,1H3/t14?,18-,19-,20+/m0/s1 BMECSLWZPCVUJH-QDHLSEFBSA-N 50140899 19-methyl-(2S,10R)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaene-2,13-diol Mu-type opioid receptor Cavia cutleri 3000 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140899 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140899&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44279664 104030435 ZINC13559694 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50205678 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@@H]3Cc1cccnc41)ccc5O InChI=1S/C20H20N2O2/c1-22-8-6-20-13-9-12-3-2-7-21-17(12)19(20)24-18-15(23)5-4-11(16(18)20)10-14(13)22/h2-5,7,13-14,19,23H,6,8-10H2,1H3/t13-,14?,19-,20-/m0/s1 AYGOLJCOJMGZAR-GEQWREAYSA-N 50140910 19-methyl-(2R,10R)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaen-13-ol Mu-type opioid receptor Cavia cutleri 3000 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140910 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140910&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44280395 104030446 ZINC13559698 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50205679 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@@H]3Cc1cc(cnc41)-c1ccc(Cl)cc1)ccc5O InChI=1S/C26H23ClN2O2/c1-29-9-8-26-19-11-16-10-17(14-2-5-18(27)6-3-14)13-28-23(16)25(26)31-24-21(30)7-4-15(22(24)26)12-20(19)29/h2-7,10,13,19-20,25,30H,8-9,11-12H2,1H3/t19-,20?,25-,26-/m0/s1 PFCJBVJVJPUGBT-FMMCSPAXSA-N 50140901 6-(4-chlorophenyl)-19-methyl-(2R,10R)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaen-13-ol Mu-type opioid receptor Cavia cutleri 900 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140901 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140901&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44280396 104030437 ZINC03943034 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50205680 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@@H]3Cc1cc(cnc41)-c1ccccc1)ccc5O InChI=1S/C26H24N2O2/c1-28-10-9-26-19-12-17-11-18(15-5-3-2-4-6-15)14-27-23(17)25(26)30-24-21(29)8-7-16(22(24)26)13-20(19)28/h2-8,11,14,19-20,25,29H,9-10,12-13H2,1H3/t19-,20?,25-,26-/m0/s1 GRNLHIJZMLLROK-FMMCSPAXSA-N 50140905 19-methyl-6-phenyl-(2R,10R)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaen-13-ol Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140905 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140905&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44279589 104030441 ZINC13559699 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50205681 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@@H]3Cc1cc(cnc41)-c1ccc(Cl)cc1Cl)ccc5O InChI=1S/C26H22Cl2N2O2/c1-30-7-6-26-18-9-14-8-15(17-4-3-16(27)11-19(17)28)12-29-23(14)25(26)32-24-21(31)5-2-13(22(24)26)10-20(18)30/h2-5,8,11-12,18,20,25,31H,6-7,9-10H2,1H3/t18-,20?,25-,26-/m0/s1 YVSJJZSJQLXGBW-JIXRRBMOSA-N 50140900 6-(2,4-dichlorophenyl)-19-methyl-(2R,10R)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaen-13-ol Mu-type opioid receptor Cavia cutleri 225 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140900 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140900&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44279841 104030436 ZINC13559702 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50205684 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@@H]3Cc1cc(cnc41)-c1ccc(Br)cc1)ccc5O InChI=1S/C26H23BrN2O2/c1-29-9-8-26-19-11-16-10-17(14-2-5-18(27)6-3-14)13-28-23(16)25(26)31-24-21(30)7-4-15(22(24)26)12-20(19)29/h2-7,10,13,19-20,25,30H,8-9,11-12H2,1H3/t19-,20?,25-,26-/m0/s1 QLUHBBPMGPGYMW-FMMCSPAXSA-N 50140898 6-(4-bromophenyl)-19-methyl-(2R,10R)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaen-13-ol Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140898 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140898&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44279588 104030434 ZINC13559700 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50205688 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@]3(O)Cc1cccnc41)ccc5O InChI=1S/C20H20N2O3/c1-22-8-6-19-15-11-4-5-13(23)17(15)25-18(19)16-12(3-2-7-21-16)10-20(19,24)14(22)9-11/h2-5,7,14,18,23-24H,6,8-10H2,1H3/t14?,18-,19-,20+/m0/s1 BMECSLWZPCVUJH-QDHLSEFBSA-N 50140899 19-methyl-(2S,10R)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaene-2,13-diol Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140899 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140899&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44279664 104030435 ZINC13559694 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50205690 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@]3(O)Cc1cc(cnc41)-c1ccccc1)ccc5O InChI=1S/C26H24N2O3/c1-28-10-9-25-21-16-7-8-19(29)23(21)31-24(25)22-17(13-26(25,30)20(28)12-16)11-18(14-27-22)15-5-3-2-4-6-15/h2-8,11,14,20,24,29-30H,9-10,12-13H2,1H3/t20?,24-,25-,26+/m0/s1 MVNIBXTXVYCLEI-OOGIKFLQSA-N 50140903 19-methyl-6-phenyl-(2S,10R)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaene-2,13-diol Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140903 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140903&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44279662 104030439 ZINC13559695 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50205691 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@@H]3Cc1cc(cnc41)-c1ccc(Cl)c(Cl)c1)ccc5O InChI=1S/C26H22Cl2N2O2/c1-30-7-6-26-17-9-15-8-16(13-2-4-18(27)19(28)10-13)12-29-23(15)25(26)32-24-21(31)5-3-14(22(24)26)11-20(17)30/h2-5,8,10,12,17,20,25,31H,6-7,9,11H2,1H3/t17-,20?,25-,26-/m0/s1 UYVJZQXUZSFCBU-MTJLISISSA-N 50140909 6-(3,4-dichlorophenyl)-19-methyl-(2R,10R)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaen-13-ol Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140909 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140909&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44279826 104030445 ZINC13559701 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50205702 Oc1ccc2C[C@H]3N(CC4CC4)CCC45C(Oc1c24)c1[nH]c2ccccc2c1CC35O InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1 WIYUZYBFCWCCQJ-XEWUMVRVSA-N 21864 (21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.0^{1,13}.0^{2,21}.0^{4,12}.0^{5,10}.0^{19,25}]pentacosa-4(12),5,7,9,15,17,19(25)-heptaene-2,16-diol::(8R)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol::NALTRINDOLE::[3H]-naltrindole Mu-type opioid receptor Cavia cutleri 3.2 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21864&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3034754 49700969 ZINC62153992 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50206762 CCCC[C@H](N(C)C(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NN[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@H](C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)C(=O)N[C@H](Cc1cn(C(=O)OC(C)(C)C)c2ccccc12)C(O)=O InChI=1S/C59H73N9O15/c1-7-8-22-48(54(76)64-46(57(80)81)31-39-34-68(58(82)83-59(3,4)5)47-23-16-15-21-41(39)47)67(6)55(77)44(32-50(71)72)62-53(75)43(29-37-19-13-10-14-20-37)66-65-42(28-36-17-11-9-12-18-36)52(74)60-33-49(70)61-35(2)51(73)63-45(56(78)79)30-38-24-26-40(69)27-25-38/h9-21,23-27,34-35,42-46,48,65-66,69H,7-8,22,28-33H2,1-6H3,(H,60,74)(H,61,70)(H,62,75)(H,63,73)(H,64,76)(H,71,72)(H,78,79)(H,80,81)/t35-,42+,43+,44+,45+,46-,48+/m1/s1 CHVZZDMXXHMJNM-BPYPMLAUSA-N 50183559 CHEMBL374325::Tyr-D-Ala-Gly-Phe-NH-NH-Phe-Asp-NMeNle-D-Trp-Boc Mu-type opioid receptor Cavia cutleri 2 ChEMBL 10.1021/jm050851n 10.7270/Q2FT8MVM 16509592 Lee, YS; Agnes, RS; Badghisi, H; Davis, P; Ma, SW; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183559 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183559&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44408526 104068032 CHEMBL374325 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50205705 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@@H]3Cc1cc(cnc41)-c1ccccc1)ccc5O InChI=1S/C26H24N2O2/c1-28-10-9-26-19-12-17-11-18(15-5-3-2-4-6-15)14-27-23(17)25(26)30-24-21(29)8-7-16(22(24)26)13-20(19)28/h2-8,11,14,19-20,25,29H,9-10,12-13H2,1H3/t19-,20?,25-,26-/m0/s1 GRNLHIJZMLLROK-FMMCSPAXSA-N 50140905 19-methyl-6-phenyl-(2R,10R)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaen-13-ol Mu-type opioid receptor Cavia cutleri 1030 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140905 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140905&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44279589 104030441 ZINC13559699 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50205723 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@@H]3Cc1cc(cnc41)-c1ccc(Cl)cc1Cl)ccc5O InChI=1S/C26H22Cl2N2O2/c1-30-7-6-26-18-9-14-8-15(17-4-3-16(27)11-19(17)28)12-29-23(14)25(26)32-24-21(31)5-2-13(22(24)26)10-20(18)30/h2-5,8,11-12,18,20,25,31H,6-7,9-10H2,1H3/t18-,20?,25-,26-/m0/s1 YVSJJZSJQLXGBW-JIXRRBMOSA-N 50140900 6-(2,4-dichlorophenyl)-19-methyl-(2R,10R)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaen-13-ol Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140900 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140900&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44279841 104030436 ZINC13559702 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50205724 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@]3(O)Cc1cc(cnc41)-c1ccc(Cl)cc1)ccc5O InChI=1S/C26H23ClN2O3/c1-29-9-8-25-21-15-4-7-19(30)23(21)32-24(25)22-16(12-26(25,31)20(29)11-15)10-17(13-28-22)14-2-5-18(27)6-3-14/h2-7,10,13,20,24,30-31H,8-9,11-12H2,1H3/t20?,24-,25-,26+/m0/s1 YMQBQNZSHDBDTL-OOGIKFLQSA-N 50140917 6-(4-chlorophenyl)-19-methyl-(2S,10R)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaene-2,13-diol Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140917&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44279831 104030453 ZINC13559696 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50205762 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@@H]3Cc1cc(cnc41)-c1ccc(Br)cc1)ccc5O InChI=1S/C26H23BrN2O2/c1-29-9-8-26-19-11-16-10-17(14-2-5-18(27)6-3-14)13-28-23(16)25(26)31-24-21(30)7-4-15(22(24)26)12-20(19)29/h2-7,10,13,19-20,25,30H,8-9,11-12H2,1H3/t19-,20?,25-,26-/m0/s1 QLUHBBPMGPGYMW-FMMCSPAXSA-N 50140898 6-(4-bromophenyl)-19-methyl-(2R,10R)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaen-13-ol Mu-type opioid receptor Cavia cutleri 3220 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140898 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140898&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44279588 104030434 ZINC13559700 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50205771 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@@H]3Cc1cccnc41)ccc5O InChI=1S/C20H20N2O2/c1-22-8-6-20-13-9-12-3-2-7-21-17(12)19(20)24-18-15(23)5-4-11(16(18)20)10-14(13)22/h2-5,7,13-14,19,23H,6,8-10H2,1H3/t13-,14?,19-,20-/m0/s1 AYGOLJCOJMGZAR-GEQWREAYSA-N 50140910 19-methyl-(2R,10R)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaen-13-ol Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140910 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140910&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44280395 104030446 ZINC13559698 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50206822 C[C@@H](CN1Cc2ccccc2C[C@H]1C(=O)NCC(=O)NCc1nc2ccccc2[nH]1)Cc1c(C)cc(O)cc1C InChI=1S/C32H37N5O3/c1-20(12-26-21(2)13-25(38)14-22(26)3)18-37-19-24-9-5-4-8-23(24)15-29(37)32(40)34-17-31(39)33-16-30-35-27-10-6-7-11-28(27)36-30/h4-11,13-14,20,29,38H,12,15-19H2,1-3H3,(H,33,39)(H,34,40)(H,35,36)/t20-,29+/m1/s1 NWCLUPOGVWVFRT-OLILMLBXSA-N 50027229 CHEMBL2375157 Mu-type opioid receptor Cavia cutleri 27 ChEMBL 10.1021/jm0603264 10.7270/Q2474BPW 16789756 Ballet, S; Salvadori, S; Trapella, C; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Negri, L; Giannini, E; Lattanzi, R; Tourwe, D; Balboni, G Vrije Universiteit Brussels http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027229 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027229&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73347271 103936746 CHEMBL2375157 ZINC29470824 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50206886 CN([C@H]1C[C@@]2(CCCO2)CC[C@@H]1N1CCCC1)C(=O)Cc1ccccc1 InChI=1S/C22H32N2O2/c1-23(21(25)16-18-8-3-2-4-9-18)20-17-22(11-7-15-26-22)12-10-19(20)24-13-5-6-14-24/h2-4,8-9,19-20H,5-7,10-17H2,1H3/t19-,20-,22+/m0/s1 PGJPPWQHDNODBR-JAXLGGSGSA-N 50381677 CHEMBL1256748::U-69593 Mu-type opioid receptor Cavia cutleri 692 ChEMBL 10.1016/j.bmcl.2006.05.060 10.7270/Q2XG9RXF 16777416 Crooks, PA; Kottayil, SG; Al-Ghananeem, AM; Byrn, SR; Butterfield, DA University of Kentucky http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50381677 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50381677&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 52947240 160860760 CHEMBL1256748 ZINC64539951 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50204728 CN1C(CCNC(=O)c2cccs2)CN=C(c2ccccc2)c2cc(Cl)ccc12 InChI=1S/C23H22ClN3OS/c1-27-18(11-12-25-23(28)21-8-5-13-29-21)15-26-22(16-6-3-2-4-7-16)19-14-17(24)9-10-20(19)27/h2-10,13-14,18H,11-12,15H2,1H3,(H,25,28) JEZGMXQLYTYHBX-UHFFFAOYSA-N 50049803 CHEMBL124015::Thiophene-2-carboxylic acid [2-(7-chloro-1-methyl-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)-ethyl]-amide Mu-type opioid receptor Cavia cutleri 69 ChEMBL 10.1021/jm0307640 10.7270/Q27M08QQ 12930147 Anzini, M; Canullo, L; Braile, C; Cappelli, A; Gallelli, A; Vomero, S; Menziani, MC; De Benedetti, PG; Rizzo, M; Collina, S; Azzolina, O; Sbacchi, M; Ghelardini, C; Galeotti, N Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049803&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10645976 103980112 CHEMBL124015 ZINC13525981 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50204730 CN1C(CCNC(=O)c2cccs2)CN=C(c2ccccc2)c2ccccc12 InChI=1S/C23H23N3OS/c1-26-18(13-14-24-23(27)21-12-7-15-28-21)16-25-22(17-8-3-2-4-9-17)19-10-5-6-11-20(19)26/h2-12,15,18H,13-14,16H2,1H3,(H,24,27) PYCHFYLMMMZMSJ-UHFFFAOYSA-N 50049806 CHEMBL127969::Thiophene-2-carboxylic acid [2-(1-methyl-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl)-ethyl]-amide Mu-type opioid receptor Cavia cutleri 6.4 ChEMBL 10.1021/jm0307640 10.7270/Q27M08QQ 12930147 Anzini, M; Canullo, L; Braile, C; Cappelli, A; Gallelli, A; Vomero, S; Menziani, MC; De Benedetti, PG; Rizzo, M; Collina, S; Azzolina, O; Sbacchi, M; Ghelardini, C; Galeotti, N Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049806&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10430432 103980115 CHEMBL127969 ZINC03955493 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50204732 Oc1ccc2C[C@H]3N(CC4CC4)CCC45C(Oc1c24)c1[nH]c2ccccc2c1CC35O InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1 WIYUZYBFCWCCQJ-XEWUMVRVSA-N 21864 (21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.0^{1,13}.0^{2,21}.0^{4,12}.0^{5,10}.0^{19,25}]pentacosa-4(12),5,7,9,15,17,19(25)-heptaene-2,16-diol::(8R)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol::NALTRINDOLE::[3H]-naltrindole Mu-type opioid receptor Cavia cutleri 15 ChEMBL 10.1021/jm0307640 10.7270/Q27M08QQ 12930147 Anzini, M; Canullo, L; Braile, C; Cappelli, A; Gallelli, A; Vomero, S; Menziani, MC; De Benedetti, PG; Rizzo, M; Collina, S; Azzolina, O; Sbacchi, M; Ghelardini, C; Galeotti, N Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21864&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3034754 49700969 ZINC62153992 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50205779 Oc1ccc2CC3[C@@H]4Cc5cc(cnc5[C@@H]5Oc1c2[C@]45CCN3CC1CC1)-c1ccc(Cl)cc1 InChI=1S/C29H27ClN2O2/c30-21-6-3-17(4-7-21)20-11-19-12-22-23-13-18-5-8-24(33)27-25(18)29(22,28(34-27)26(19)31-14-20)9-10-32(23)15-16-1-2-16/h3-8,11,14,16,22-23,28,33H,1-2,9-10,12-13,15H2/t22-,23?,28-,29-/m0/s1 GSOFQIRSCHLMHR-OPECHTPQSA-N 50140913 6-(4-chlorophenyl)-19-cyclopropylmethyl-(2R,10R)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaen-13-ol Mu-type opioid receptor Cavia cutleri 9.2 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140913 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140913&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44279825 104030449 ZINC13559703 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50205792 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45C(Oc1c24)c1ncc(cc1C[C@@]35O)-c1ccc(Cl)cc1 InChI=1S/C29H27ClN2O3/c30-21-6-3-17(4-7-21)20-11-19-13-29(34)23-12-18-5-8-22(33)26-24(18)28(29,27(35-26)25(19)31-14-20)9-10-32(23)15-16-1-2-16/h3-8,11,14,16,23,27,33-34H,1-2,9-10,12-13,15H2/t23-,27?,28+,29-/m1/s1 WRVDUHKCIPYGNZ-VKZBBXDISA-N 50080467 5'-(Chlorophenyl)-17-(cyclopropylmethyl) -6,7-didehydro-3,14-dihydroxy-4,5alpha-epoxypyrido-[2',3':6,7]morphinan::CHEMBL325600 Mu-type opioid receptor Cavia cutleri 7.8 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080467&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9913318 103980624 CHEMBL325600 ZINC27109331 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50202525 CC(C)[C@@H](CN1CC[C@](C)([C@@H](C)C1)c1cccc(O)c1)NC(=O)CCc1ccc(O)cc1 InChI=1S/C27H38N2O3/c1-19(2)25(28-26(32)13-10-21-8-11-23(30)12-9-21)18-29-15-14-27(4,20(3)17-29)22-6-5-7-24(31)16-22/h5-9,11-12,16,19-20,25,30-31H,10,13-15,17-18H2,1-4H3,(H,28,32)/t20-,25+,27+/m0/s1 BOXRUELCJUEBJH-FBQMUFCQSA-N 50102710 3-(4-Hydroxy-phenyl)-N-{(S)-1-[(3R,4R)-4-(3-hydroxy-phenyl)-3,4-dimethyl-piperidin-1-ylmethyl]-2-methyl-propyl}-propionamide::3-(4-Hydroxy-phenyl)-N-{1-[4-(3-hydroxy-phenyl)-3,4-dimethyl-piperidin-1-ylmethyl]-2-methyl-propyl}-propionamide::CHEMBL10986 Mu-type opioid receptor Cavia cutleri 7.3 ChEMBL 10.1021/jm015521r 10.7270/Q25T3M58 11495579 Thomas, JB; Atkinson, RN; Rothman, RB; Fix, SE; Mascarella, SW; Vinson, NA; Xu, H; Dersch, CM; Lu, Y; Cantrell, BE; Zimmerman, DM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102710 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102710&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9804952 103999146 CHEMBL10986 ZINC04424128 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50202542 CC(C)[C@@H](CN1CC[C@](C)([C@@H](C)C1)c1cccc(O)c1)NC(=O)C1Cc2ccc(O)cc2CN1 InChI=1S/C28H39N3O3/c1-18(2)26(30-27(34)25-13-20-8-9-24(33)12-21(20)15-29-25)17-31-11-10-28(4,19(3)16-31)22-6-5-7-23(32)14-22/h5-9,12,14,18-19,25-26,29,32-33H,10-11,13,15-17H2,1-4H3,(H,30,34)/t19-,25?,26+,28+/m0/s1 ZLVXBBHTMQJRSX-HUUIFEGFSA-N 50102711 7-Hydroxy-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid {1-[4-(3-hydroxy-phenyl)-3,4-dimethyl-piperidin-1-ylmethyl]-2-methyl-propyl}-amide::CHEMBL51204 Mu-type opioid receptor Cavia cutleri 2.2 ChEMBL 10.1021/jm015521r 10.7270/Q25T3M58 11495579 Thomas, JB; Atkinson, RN; Rothman, RB; Fix, SE; Mascarella, SW; Vinson, NA; Xu, H; Dersch, CM; Lu, Y; Cantrell, BE; Zimmerman, DM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102711 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102711&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44295810 103999147 CHEMBL51204 ZINC36215338 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50202547 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2[C@@H]4Oc6c7c(C[C@H]8N(CC9CC9)CC[C@@]47[C@@]8(O)Cc2c1C[C@@]35O)ccc6O InChI=1S/C40H43N3O6/c44-25-7-5-21-13-27-39(46)15-23-24-16-40(47)28-14-22-6-8-26(45)34-30(22)38(40,10-12-43(28)18-20-3-4-20)36(49-34)32(24)41-31(23)35-37(39,29(21)33(25)48-35)9-11-42(27)17-19-1-2-19/h5-8,19-20,27-28,35-36,41,44-47H,1-4,9-18H2/t27-,28-,35+,36+,37+,38+,39-,40-/m1/s1 APSUXPSYBJVPPS-YAUKWVCOSA-N 82551 C18130::CAS_105618-26-6::NOR-BNI (HCI)2::NORBNI Mu-type opioid receptor Cavia cutleri 17 ChEMBL 10.1021/jm015521r 10.7270/Q25T3M58 11495579 Thomas, JB; Atkinson, RN; Rothman, RB; Fix, SE; Mascarella, SW; Vinson, NA; Xu, H; Dersch, CM; Lu, Y; Cantrell, BE; Zimmerman, DM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82551&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5480230 136350521 C18130 ZINC03995590 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50203617 CCO[C@]12Cc3c([nH]c4ccccc34)[C@]3(C)Oc4c5c(CC1N(CC1CC1)CCC235)ccc4O InChI=1S/C29H32N2O3/c1-3-33-29-15-20-19-6-4-5-7-21(19)30-26(20)27(2)28(29)12-13-31(16-17-8-9-17)23(29)14-18-10-11-22(32)25(34-27)24(18)28/h4-7,10-11,17,23,30,32H,3,8-9,12-16H2,1-2H3/t23?,27-,28?,29+/m0/s1 OMUSJJBIQWMCAN-SXNYVGIYSA-N 50121331 22-cyclopropylmethyl-2-ethoxy-13-methyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaen-16-ol::Naltrindole analogue Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm020940p 10.7270/Q2R21244 12431065 Schutz, J; Dersch, CM; Horel, R; Spetea, M; Koch, M; Meditz, R; Greiner, E; Rothman, RB; Schmidhammer, H University of Innsbruck http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50121331 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50121331&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44366521 104014198 ZINC27563289 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50203627 CCO[C@]12Cc3c(oc4ccccc34)[C@@H]3Oc4c5c(C[C@H]1N(CC1CC1)CC[C@@]235)ccc4O InChI=1S/C28H29NO4/c1-2-31-28-14-19-18-5-3-4-6-21(18)32-24(19)26-27(28)11-12-29(15-16-7-8-16)22(28)13-17-9-10-20(30)25(33-26)23(17)27/h3-6,9-10,16,22,26,30H,2,7-8,11-15H2,1H3/t22-,26+,27+,28-/m1/s1 WGBLEWOROOAZNK-CSZVXOJQSA-N 50026994 CHEMBL2113646 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm020940p 10.7270/Q2R21244 12431065 Schutz, J; Dersch, CM; Horel, R; Spetea, M; Koch, M; Meditz, R; Greiner, E; Rothman, RB; Schmidhammer, H University of Innsbruck http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026994&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10343372 103936578 CHEMBL2113646 ZINC29343037 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50203629 Oc1ccc2C[C@H]3N(CC4CC4)CCC45C(Oc1c24)c1[nH]c2ccccc2c1CC35O InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1 WIYUZYBFCWCCQJ-XEWUMVRVSA-N 21864 (21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.0^{1,13}.0^{2,21}.0^{4,12}.0^{5,10}.0^{19,25}]pentacosa-4(12),5,7,9,15,17,19(25)-heptaene-2,16-diol::(8R)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol::NALTRINDOLE::[3H]-naltrindole Mu-type opioid receptor Cavia cutleri 3.2 ChEMBL 10.1021/jm020940p 10.7270/Q2R21244 12431065 Schutz, J; Dersch, CM; Horel, R; Spetea, M; Koch, M; Meditz, R; Greiner, E; Rothman, RB; Schmidhammer, H University of Innsbruck http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21864&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3034754 49700969 ZINC62153992 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50203651 CCO[C@]12Cc3c([nH]c4ccccc34)[C@@H]3Oc4c5c(C[C@H]1N(CC=C)CC[C@@]235)ccc4O InChI=1S/C27H28N2O3/c1-3-12-29-13-11-26-22-16-9-10-20(30)24(22)32-25(26)23-18(17-7-5-6-8-19(17)28-23)15-27(26,31-4-2)21(29)14-16/h3,5-10,21,25,28,30H,1,4,11-15H2,2H3/t21-,25+,26+,27-/m1/s1 DIAAKKARDRDKAQ-NVSKSXHLSA-N 50026996 CHEMBL2113654 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm020940p 10.7270/Q2R21244 12431065 Schutz, J; Dersch, CM; Horel, R; Spetea, M; Koch, M; Meditz, R; Greiner, E; Rothman, RB; Schmidhammer, H University of Innsbruck http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026996&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10907487 103936580 CHEMBL2113654 ZINC06095254 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50204744 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 3 ChEMBL 10.1021/jm0307640 10.7270/Q27M08QQ 12930147 Anzini, M; Canullo, L; Braile, C; Cappelli, A; Gallelli, A; Vomero, S; Menziani, MC; De Benedetti, PG; Rizzo, M; Collina, S; Azzolina, O; Sbacchi, M; Ghelardini, C; Galeotti, N Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50204761 CN1C(CCNC(=O)c2ccsc2)CN=C(c2ccccc2F)c2ccccc12 InChI=1S/C23H22FN3OS/c1-27-17(10-12-25-23(28)16-11-13-29-15-16)14-26-22(18-6-2-4-8-20(18)24)19-7-3-5-9-21(19)27/h2-9,11,13,15,17H,10,12,14H2,1H3,(H,25,28) AVUSYTRJVKZPGP-UHFFFAOYSA-N 50131968 CHEMBL127828::Thiophene-3-carboxylic acid {2-[5-(2-fluoro-phenyl)-1-methyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl]-ethyl}-amide Mu-type opioid receptor Cavia cutleri 1.9 ChEMBL 10.1021/jm0307640 10.7270/Q27M08QQ 12930147 Anzini, M; Canullo, L; Braile, C; Cappelli, A; Gallelli, A; Vomero, S; Menziani, MC; De Benedetti, PG; Rizzo, M; Collina, S; Azzolina, O; Sbacchi, M; Ghelardini, C; Galeotti, N Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131968 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131968&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44349947 104022993 CHEMBL127828 ZINC27298377 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50207090 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1 DQCKKXVULJGBQN-XFWGSAIBSA-N 60212 (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::MLS000069607::NALTREXONE HYDROCHLORIDE::SMR000058767::US10988481, Compound NTX::US9107954, naltrexone::cid_5485201 Mu-type opioid receptor Cavia cutleri 0.400000 ChEMBL 10.1021/jm060595u 10.7270/Q24X58MF 17004724 Rennison, D; Moynihan, H; Traynor, JR; Lewis, JW; Husbands, SM University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60212&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5360515 252639834 DB00704 C07253 ZINC00001773 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50204997 CN([C@H]1C[C@@]2(CCCO2)CC[C@@H]1N1CCCC1)C(=O)Cc1ccccc1 InChI=1S/C22H32N2O2/c1-23(21(25)16-18-8-3-2-4-9-18)20-17-22(11-7-15-26-22)12-10-19(20)24-13-5-6-14-24/h2-4,8-9,19-20H,5-7,10-17H2,1H3/t19-,20-,22+/m0/s1 PGJPPWQHDNODBR-JAXLGGSGSA-N 50381677 CHEMBL1256748::U-69593 Mu-type opioid receptor Cavia cutleri 1880 ChEMBL 10.1021/jm0307640 10.7270/Q27M08QQ 12930147 Anzini, M; Canullo, L; Braile, C; Cappelli, A; Gallelli, A; Vomero, S; Menziani, MC; De Benedetti, PG; Rizzo, M; Collina, S; Azzolina, O; Sbacchi, M; Ghelardini, C; Galeotti, N Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50381677 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50381677&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 52947240 160860760 CHEMBL1256748 ZINC64539951 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50201767 Oc1ccc2C[C@H]3N(CC4CC4)CCC45C(Oc1c24)c1[nH]c2ccccc2c1CC35O InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1 WIYUZYBFCWCCQJ-XEWUMVRVSA-N 21864 (21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.0^{1,13}.0^{2,21}.0^{4,12}.0^{5,10}.0^{19,25}]pentacosa-4(12),5,7,9,15,17,19(25)-heptaene-2,16-diol::(8R)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol::NALTRINDOLE::[3H]-naltrindole Mu-type opioid receptor Cavia cutleri 3.2 ChEMBL 10.1021/jm9807003 10.7270/Q24M957P 10229636 Coop, A; Rothman, RB; Dersch, C; Partilla, J; Porreca, F; Davis, P; Jacobson, AE; Rice, KC National Institute of Diabetes http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21864&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3034754 49700969 ZINC62153992 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50201773 COc1ccc2C[C@@H]3[C@@H]4Cc5c(C[C@]4(CCN3CC3CC3)c2c1O)[nH]c1ccccc51 InChI=1S/C27H30N2O2/c1-31-24-9-8-17-12-23-20-13-19-18-4-2-3-5-21(18)28-22(19)14-27(20,25(17)26(24)30)10-11-29(23)15-16-6-7-16/h2-5,8-9,16,20,23,28,30H,6-7,10-15H2,1H3/t20-,23+,27-/m0/s1 ZCFDNOOYINVEBV-OSADXMDESA-N 50076496 17-cyclopropylmethyl-6,7-didehydro-4-hydroxy-3-methoxy-6,7:2',3'-indolmorphinan::CHEMBL296230 Mu-type opioid receptor Cavia cutleri >1250 ChEMBL 10.1021/jm9807003 10.7270/Q24M957P 10229636 Coop, A; Rothman, RB; Dersch, C; Partilla, J; Porreca, F; Davis, P; Jacobson, AE; Rice, KC National Institute of Diabetes http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076496 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076496&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10811744 103969368 CHEMBL296230 ZINC03931532 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50201782 C[C@H]1[C@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CC1CC1 InChI=1S/C18H25NO/c1-12-17-9-14-5-6-15(20)10-16(14)18(12,2)7-8-19(17)11-13-3-4-13/h5-6,10,12-13,17,20H,3-4,7-9,11H2,1-2H3/t12-,17+,18+/m0/s1 YQYVFVRQLZMJKJ-JBBXEZCESA-N 50001023 (2R,6R,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL56585::Cyclazocine::US10231963, Table B.9::US10736890, Compound TABLE B.9::US11534436, Compound Table B.9::US9656961, Example 00126 Mu-type opioid receptor Cavia cutleri 0.100000 ChEMBL 10.1021/jm9903343 10.7270/Q20V8DGH 10633042 Neumeyer, JL; Bidlack, JM; Zong, R; Bakthavachalam, V; Gao, P; Cohen, DJ; Negus, SS; Mello, NK Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001023&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3037926 103915556 CHEMBL56585 ZINC03830613 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50201783 Oc1ccc2C[C@@H]3C4CCCC[C@]4(CCN3C[C@@H]3CCCO3)c2c1 InChI=1S/C21H29NO2/c23-16-7-6-15-12-20-18-5-1-2-8-21(18,19(15)13-16)9-10-22(20)14-17-4-3-11-24-17/h6-7,13,17-18,20,23H,1-5,8-12,14H2/t17-,18?,20+,21+/m0/s1 YCCQBABDNDRWSN-MWBYQJBMSA-N 50180190 (1R,9R)-17-[(2S)-oxolan-2-ylmethyl]-17-azatetracyclo[7.5.3.0^{1,10}.0^{2,7}]heptadeca-2(7),3,5-trien-4-ol::CHEMBL199832 Mu-type opioid receptor Cavia cutleri 0.010000 ChEMBL 10.1021/jm9903343 10.7270/Q20V8DGH 10633042 Neumeyer, JL; Bidlack, JM; Zong, R; Bakthavachalam, V; Gao, P; Cohen, DJ; Negus, SS; Mello, NK Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180190&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44406663 104065323 CHEMBL199832 ZINC28566608 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50201814 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 0.880000 ChEMBL 10.1021/jm000119i 10.7270/Q269749X 11000010 Wentland, MP; Duan, W; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50201815 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5N InChI=1S/C17H20N2O2/c1-19-7-6-17-10-3-5-13(20)16(17)21-15-11(18)4-2-9(14(15)17)8-12(10)19/h2-5,10,12-13,16,20H,6-8,18H2,1H3/t10-,12+,13-,16-,17-/m0/s1 PZLCJJYWLQBTCE-UBMAESPOSA-N 50369585 CHEMBL333959 Mu-type opioid receptor Cavia cutleri 53 ChEMBL 10.1021/jm000119i 10.7270/Q269749X 11000010 Wentland, MP; Duan, W; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369585 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369585&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10850629 160848687 CHEMBL333959 ZINC13813266 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50201819 CN(C)c1ccc2C[C@@H]3[C@@H]4C=C[C@H](O)[C@@H]5Oc1c2[C@]45CCN3C InChI=1S/C19H24N2O2/c1-20(2)13-6-4-11-10-14-12-5-7-15(22)18-19(12,8-9-21(14)3)16(11)17(13)23-18/h4-7,12,14-15,18,22H,8-10H2,1-3H3/t12-,14+,15-,18-,19-/m0/s1 YXIFVFDHQODFOW-SKOJWQBXSA-N 50369588 CHEMBL119332 Mu-type opioid receptor Cavia cutleri 240 ChEMBL 10.1021/jm000119i 10.7270/Q269749X 11000010 Wentland, MP; Duan, W; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369588 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369588&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10757499 160848690 CHEMBL119332 ZINC13813272 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50201820 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5NCc1ccccc1 InChI=1S/C24H26N2O2/c1-26-12-11-24-17-8-10-20(27)23(24)28-22-18(25-14-15-5-3-2-4-6-15)9-7-16(21(22)24)13-19(17)26/h2-10,17,19-20,23,25,27H,11-14H2,1H3/t17-,19+,20-,23-,24-/m0/s1 IYILOENZYSJADU-UPQYSNQFSA-N 50369589 CHEMBL332927 Mu-type opioid receptor Cavia cutleri 33 ChEMBL 10.1021/jm000119i 10.7270/Q269749X 11000010 Wentland, MP; Duan, W; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369589 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369589&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10022299 160848691 CHEMBL332927 ZINC13813277 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50201821 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5Nc1ccccc1 InChI=1S/C23H24N2O2/c1-25-12-11-23-16-8-10-19(26)22(23)27-21-17(24-15-5-3-2-4-6-15)9-7-14(20(21)23)13-18(16)25/h2-10,16,18-19,22,24,26H,11-13H2,1H3/t16-,18+,19-,22-,23-/m0/s1 BLCLKJDNXQERRY-QHFYENJSSA-N 50369590 CHEMBL333965 Mu-type opioid receptor Cavia cutleri 59 ChEMBL 10.1021/jm000119i 10.7270/Q269749X 11000010 Wentland, MP; Duan, W; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369590 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369590&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10546451 160848692 CHEMBL333965 ZINC13813274 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50201825 CNc1ccc2C[C@@H]3[C@@H]4C=C[C@H](O)[C@@H]5Oc1c2[C@]45CCN3C InChI=1S/C18H22N2O2/c1-19-12-5-3-10-9-13-11-4-6-14(21)17-18(11,7-8-20(13)2)15(10)16(12)22-17/h3-6,11,13-14,17,19,21H,7-9H2,1-2H3/t11-,13+,14-,17-,18-/m0/s1 KKYZBPZKVOKDDQ-LOMUYOJASA-N 50369587 CHEMBL119692 Mu-type opioid receptor Cavia cutleri 63 ChEMBL 10.1021/jm000119i 10.7270/Q269749X 11000010 Wentland, MP; Duan, W; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369587 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369587&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10542105 160848689 CHEMBL119692 ZINC13813269 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50201828 C[C@H]1[C@H]2Cc3ccc(Nc4ccccc4)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C24H30N2/c1-17-23-14-19-10-11-21(25-20-6-4-3-5-7-20)15-22(19)24(17,2)12-13-26(23)16-18-8-9-18/h3-7,10-11,15,17-18,23,25H,8-9,12-14,16H2,1-2H3/t17-,23?,24-/m0/s1 FUMBLBJFVJXVBV-LZCUNHEZSA-N 50085020 ((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-phenyl-amine::(3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-phenyl-amine::CHEMBL2367916 Mu-type opioid receptor Cavia cutleri 1.1 ChEMBL 10.1021/jm000119i 10.7270/Q269749X 11000010 Wentland, MP; Duan, W; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085020&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73351393 103984503 CHEMBL2367916 ZINC13493416 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50201830 C[C@H]1[C@H]2Cc3ccc(N)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C18H26N2/c1-12-17-9-14-5-6-15(19)10-16(14)18(12,2)7-8-20(17)11-13-3-4-13/h5-6,10,12-13,17H,3-4,7-9,11,19H2,1-2H3/t12-,17+,18-/m0/s1 STNPURITMRUHGJ-RZAIGCCYSA-N 50092176 3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ylamine::CHEMBL332017 Mu-type opioid receptor Cavia cutleri 1.8 ChEMBL 10.1021/jm000119i 10.7270/Q269749X 11000010 Wentland, MP; Duan, W; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092176&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 12994686 103990366 CHEMBL332017 ZINC13493411 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50201834 C[C@H]1[C@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CC1CC1 InChI=1S/C18H25NO/c1-12-17-9-14-5-6-15(20)10-16(14)18(12,2)7-8-19(17)11-13-3-4-13/h5-6,10,12-13,17,20H,3-4,7-9,11H2,1-2H3/t12-,17+,18+/m0/s1 YQYVFVRQLZMJKJ-JBBXEZCESA-N 50001023 (2R,6R,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL56585::Cyclazocine::US10231963, Table B.9::US10736890, Compound TABLE B.9::US11534436, Compound Table B.9::US9656961, Example 00126 Mu-type opioid receptor Cavia cutleri 0.100000 ChEMBL 10.1021/jm000119i 10.7270/Q269749X 11000010 Wentland, MP; Duan, W; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001023&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3037926 103915556 CHEMBL56585 ZINC03830613 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50205193 CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23-,24-/m0/s1 MCMMCRYPQBNCPH-DVKRWUGUSA-N 50001683 13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid::7-Benzyl-10-{[3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL294616::DPDPE Mu-type opioid receptor Cavia cutleri 7300 ChEMBL 10.1021/jm0303103 10.7270/Q2JW8FM1 13678399 Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001683&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299404 103916113 CHEMBL294616 ZINC27520031 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50205194 C[C@@H]([C@@H](N)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(O)=O)C(C)(C)S)C(C)(C)S)c1c(C)cc(O)cc1C InChI=1S/C33H47N5O7S2/c1-17-13-21(39)14-18(2)24(17)19(3)25(34)29(42)37-26(32(4,5)46)30(43)35-16-23(40)36-22(15-20-11-9-8-10-12-20)28(41)38-27(31(44)45)33(6,7)47/h8-14,19,22,25-27,39,46-47H,15-16,34H2,1-7H3,(H,35,43)(H,36,40)(H,37,42)(H,38,41)(H,44,45)/t19-,22+,25-,26-,27-/m1/s1 FKKHZZDLSPFFPR-NNPYHWQPSA-N 50133261 CHEMBL134652::[(2R,3R)-TMT1]DPDPE Mu-type opioid receptor Cavia cutleri 50000 ChEMBL 10.1021/jm0303103 10.7270/Q2JW8FM1 13678399 Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133261 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133261&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44356081 104024168 CHEMBL134652 ZINC27425627 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50205196 C[C@H]([C@H](N)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(O)=O)C(C)(C)S)C(C)(C)S)c1c(C)cc(O)cc1C InChI=1S/C33H47N5O7S2/c1-17-13-21(39)14-18(2)24(17)19(3)25(34)29(42)37-26(32(4,5)46)30(43)35-16-23(40)36-22(15-20-11-9-8-10-12-20)28(41)38-27(31(44)45)33(6,7)47/h8-14,19,22,25-27,39,46-47H,15-16,34H2,1-7H3,(H,35,43)(H,36,40)(H,37,42)(H,38,41)(H,44,45)/t19-,22-,25-,26+,27+/m0/s1 FKKHZZDLSPFFPR-IFBOTDGJSA-N 50133264 CHEMBL133719::[(2S,3S)-TMT1]DPDPE Mu-type opioid receptor Cavia cutleri 290 ChEMBL 10.1021/jm0303103 10.7270/Q2JW8FM1 13678399 Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133264 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133264&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44355639 104024170 CHEMBL133719 ZINC27417701 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50204106 C[C@H]1CN(C\C=C\c2ccccc2)CC[C@@]1(C)c1cccc(O)c1 InChI=1S/C22H27NO/c1-18-17-23(14-7-10-19-8-4-3-5-9-19)15-13-22(18,2)20-11-6-12-21(24)16-20/h3-12,16,18,24H,13-15,17H2,1-2H3/b10-7+/t18-,22+/m0/s1 SUIRCGLIUIROIR-SRHFXGPLSA-N 50064521 3-[(3R,4R)-3,4-Dimethyl-1-((E)-3-phenyl-allyl)-piperidin-4-yl]-phenol::3-[3,4-Dimethyl-1-(3-phenyl-allyl)-piperidin-4-yl]-phenol::CHEMBL51838 Mu-type opioid receptor Cavia cutleri 0.740000 ChEMBL 10.1021/jm030092d 10.7270/Q2FF3T3J 12723940 Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064521 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064521&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9973387 103959538 CHEMBL51838 ZINC13779625 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50204139 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1 DQCKKXVULJGBQN-XFWGSAIBSA-N 60212 (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::MLS000069607::NALTREXONE HYDROCHLORIDE::SMR000058767::US10988481, Compound NTX::US9107954, naltrexone::cid_5485201 Mu-type opioid receptor Cavia cutleri 1.4 ChEMBL 10.1021/jm030092d 10.7270/Q2FF3T3J 12723940 Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60212&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5360515 252639834 DB00704 C07253 ZINC00001773 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50204147 C[C@H]1CN(C\C=C\c2ccccc2C)CC[C@@]1(C)c1cccc(O)c1 InChI=1S/C23H29NO/c1-18-8-4-5-9-20(18)10-7-14-24-15-13-23(3,19(2)17-24)21-11-6-12-22(25)16-21/h4-12,16,19,25H,13-15,17H2,1-3H3/b10-7+/t19-,23+/m0/s1 FJFLDQXXCJUUBR-XECBNOGISA-N 50064515 3-[(3R,4R)-3,4-Dimethyl-1-((E)-3-o-tolyl-allyl)-piperidin-4-yl]-phenol::3-[(3R,4R)-3,4-Dimethyl-1-(3-o-tolyl-allyl)-piperidin-4-yl]-phenol::3-[3,4-Dimethyl-1-(3-o-tolyl-allyl)-piperidin-4-yl]-phenol::CHEMBL52451::RTI-5989-25 Mu-type opioid receptor Cavia cutleri 0.860000 ChEMBL 10.1021/jm030092d 10.7270/Q2FF3T3J 12723940 Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064515 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064515&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9840689 103959532 CHEMBL52451 ZINC13532660 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50204159 C[C@H]1CN(CC[C@H](O)C2CCCCC2)CC[C@@]1(C)c1cccc(O)c1 InChI=1S/C22H35NO2/c1-17-16-23(13-11-21(25)18-7-4-3-5-8-18)14-12-22(17,2)19-9-6-10-20(24)15-19/h6,9-10,15,17-18,21,24-25H,3-5,7-8,11-14,16H2,1-2H3/t17-,21-,22+/m0/s1 LVVHEFJXPXAUDD-BULFRSBZSA-N 50045775 (3R,4R)3-[1-(3-Cyclohexyl-3-hydroxy-propyl)-3,4-dimethyl-piperidin-4-yl]-phenol::3-((3R,4R)-1-((S)-3-cyclohexyl-3-hydroxypropyl)-3,4-dimethylpiperidin-4-yl)phenol::3-[(3R,4R)-1-((S)-3-Cyclohexyl-3-hydroxy-propyl)-3,4-dimethyl-piperidin-4-yl]-phenol::3-[1-(3-Cyclohexyl-3-hydroxy-propyl)-3,4-dimethyl-piperidin-4-yl]-phenol::CHEMBL300662::LY-255582 Mu-type opioid receptor Cavia cutleri 0.320000 ChEMBL 10.1021/jm030092d 10.7270/Q2FF3T3J 12723940 Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045775&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9906198 103976648 CHEMBL300662 C03491 ZINC03783617 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50212042 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1 DQCKKXVULJGBQN-XFWGSAIBSA-N 60212 (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::MLS000069607::NALTREXONE HYDROCHLORIDE::SMR000058767::US10988481, Compound NTX::US9107954, naltrexone::cid_5485201 Mu-type opioid receptor Cavia cutleri 0.400000 ChEMBL 10.1021/jm8012272 10.7270/Q2G44R6N 19253983 Moynihan, H; Jales, AR; Greedy, BM; Rennison, D; Broadbear, JH; Purington, L; Traynor, JR; Woods, JH; Lewis, JW; Husbands, SM University of Bath http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60212&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5360515 252639834 DB00704 C07253 ZINC00001773 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50211566 C[C@H]1[C@@H]2N(CC3CC3)CC[C@@]1(C)c1cc(O)ccc1C2=O InChI=1S/C18H23NO2/c1-11-16-17(21)14-6-5-13(20)9-15(14)18(11,2)7-8-19(16)10-12-3-4-12/h5-6,9,11-12,16,20H,3-4,7-8,10H2,1-2H3/t11-,16-,18+/m0/s1 HQBZLVPZOGIAIQ-SDDDUWNISA-N 50027366 Ketazocine::US10081602, Example Ketazocine::US10865186, Compound Ketazocine::US9688638, Ketazocine::WIN-34276 Mu-type opioid receptor Cavia cutleri 3.3 ChEMBL 10.1016/j.bmcl.2008.10.134 10.7270/Q2RX9D1K 19027293 Wentland, MP; Lou, R; Lu, Q; Bu, Y; VanAlstine, MA; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027366 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027366&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3054741 103936839 ZINC27873243 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50212719 CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21+,23-,24-/m0/s1 MCMMCRYPQBNCPH-DVKRWUGUSA-N 50001683 13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid::7-Benzyl-10-{[3-(4-hydroxy-phenyl)-pyrrolidine-2-carbonyl]-amino}-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL294616::DPDPE Mu-type opioid receptor Cavia cutleri 2720 ChEMBL 10.1021/jm900473p 10.7270/Q2MC90ZZ 20560643 Yamamoto, T; Nair, P; Jacobsen, NE; Vagner, J; Kulkarni, V; Davis, P; Ma, SW; Navratilova, E; Yamamura, HI; Vanderah, TW; Porreca, F; Lai, J; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001683&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299404 103916113 CHEMBL294616 ZINC27520031 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50236607 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C46H56N10O10/c1-27(51-43(63)35(47)21-31-13-17-33(57)18-14-31)41(61)49-25-39(59)53-37(23-29-9-5-3-6-10-29)45(65)55-56-46(66)38(24-30-11-7-4-8-12-30)54-40(60)26-50-42(62)28(2)52-44(64)36(48)22-32-15-19-34(58)20-16-32/h3-20,27-28,35-38,57-58H,21-26,47-48H2,1-2H3,(H,49,61)(H,50,62)(H,51,63)(H,52,64)(H,53,59)(H,54,60)(H,55,65)(H,56,66)/t27-,28-,35+,36+,37+,38+/m1/s1 DESSEGDLRYOPTJ-VRANXALZSA-N 21014 (2S)-2-amino-N-[(1R)-1-[({[(1S)-1-{N'-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanoyl]hydrazinecarbonyl}-2-phenylethyl]carbamoyl}methyl)carbamoyl]ethyl]-3-(4-hydroxyphenyl)propanamide::(Tyr-Ala-Gly-Phe-NH2)2::Biphalin::CHEMBL200199::bis(Tyr-Ala-Gly-PheNH2)hydrazide::enkephalin dimer Mu-type opioid receptor Cavia cutleri 8.8 ChEMBL 10.1021/ml500241n 10.7270/Q23T9JS5 25221662 Mollica, A; Carotenuto, A; Novellino, E; Limatola, A; Costante, R; Pinnen, F; Stefanucci, A; Pieretti, S; Borsodi, A; Samavati, R; Zador, F; Benyhe, S; Davis, P; Porreca, F; Hruby, VJ Universit£ di Chieti-Pescara"G. d'Annunzio" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21014&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5487663 49689087 CHEMBL200199 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50236608 CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@@H](Cc2ccccc2)C(=O)NNC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H]1NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C50H62N10O10S2/c1-49(2)41(57-43(65)35(51)23-31-15-19-33(61)20-16-31)47(69)53-27-39(63)55-37(25-29-11-7-5-8-12-29)45(67)59-60-46(68)38(26-30-13-9-6-10-14-30)56-40(64)28-54-48(70)42(50(3,4)72-71-49)58-44(66)36(52)24-32-17-21-34(62)22-18-32/h5-22,35-38,41-42,61-62H,23-28,51-52H2,1-4H3,(H,53,69)(H,54,70)(H,55,63)(H,56,64)(H,57,65)(H,58,66)(H,59,67)(H,60,68)/t35-,36-,37-,38-,41-,42-/m0/s1 BNEJMYFGXBQLFU-CIJOKURBSA-N 50026762 CHEMBL3331510 Mu-type opioid receptor Cavia cutleri 21 ChEMBL 10.1021/ml500241n 10.7270/Q23T9JS5 25221662 Mollica, A; Carotenuto, A; Novellino, E; Limatola, A; Costante, R; Pinnen, F; Stefanucci, A; Pieretti, S; Borsodi, A; Samavati, R; Zador, F; Benyhe, S; Davis, P; Porreca, F; Hruby, VJ Universit£ di Chieti-Pescara"G. d'Annunzio" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026762&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 118713810 103936346 CHEMBL3331510 ZINC27652676 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50255599 C[C@H]([C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O)c1ccccc1 InChI=1S/C33H39N5O5/c1-21(24-11-6-3-7-12-24)29(30(35)40)37-31(41)27(20-22-9-4-2-5-10-22)36-32(42)28-13-8-18-38(28)33(43)26(34)19-23-14-16-25(39)17-15-23/h2-7,9-12,14-17,21,26-29,39H,8,13,18-20,34H2,1H3,(H2,35,40)(H,36,42)(H,37,41)/t21-,26-,27-,28-,29-/m0/s1 XEDWKSFZTLIHLE-VRTFYRIBSA-N 50139015 (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((1S,2S)-1-carbamoyl-2-phenyl-propylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL436039 Mu-type opioid receptor Cavia cutleri 3.46 ChEMBL 10.1021/jm0310028 10.7270/Q2J965TS 14736254 Tomboly, C; Kover, KE; Peter, A; Tourwe, D; Biyashev, D; Benyhe, S; Borsodi, A; Al-Khrasani, M; Ronai, AZ; Toth, G Biological Research Center of the Hungarian Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139015&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44376889 104029002 CHEMBL436039 ZINC27855322 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50255606 C[C@@H]([C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O)c1ccccc1 InChI=1S/C33H39N5O5/c1-21(24-11-6-3-7-12-24)29(30(35)40)37-31(41)27(20-22-9-4-2-5-10-22)36-32(42)28-13-8-18-38(28)33(43)26(34)19-23-14-16-25(39)17-15-23/h2-7,9-12,14-17,21,26-29,39H,8,13,18-20,34H2,1H3,(H2,35,40)(H,36,42)(H,37,41)/t21-,26+,27+,28+,29+/m1/s1 XEDWKSFZTLIHLE-GYZIEVATSA-N 50139012 (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((1S,2R)-1-carbamoyl-2-phenyl-propylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL163334 Mu-type opioid receptor Cavia cutleri 89.9 ChEMBL 10.1021/jm0310028 10.7270/Q2J965TS 14736254 Tomboly, C; Kover, KE; Peter, A; Tourwe, D; Biyashev, D; Benyhe, S; Borsodi, A; Al-Khrasani, M; Ronai, AZ; Toth, G Biological Research Center of the Hungarian Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139012&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377239 104028999 CHEMBL163334 ZINC27766155 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50255609 C[C@H]([C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O)c1ccccc1 InChI=1S/C33H39N5O5/c1-21(24-11-6-3-7-12-24)29(30(35)40)37-31(41)27(20-22-9-4-2-5-10-22)36-32(42)28-13-8-18-38(28)33(43)26(34)19-23-14-16-25(39)17-15-23/h2-7,9-12,14-17,21,26-29,39H,8,13,18-20,34H2,1H3,(H2,35,40)(H,36,42)(H,37,41)/t21-,26-,27-,28-,29+/m0/s1 XEDWKSFZTLIHLE-YTFADBMMSA-N 50139011 (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((1R,2S)-1-carbamoyl-2-phenyl-propylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL349738 Mu-type opioid receptor Cavia cutleri 589 ChEMBL 10.1021/jm0310028 10.7270/Q2J965TS 14736254 Tomboly, C; Kover, KE; Peter, A; Tourwe, D; Biyashev, D; Benyhe, S; Borsodi, A; Al-Khrasani, M; Ronai, AZ; Toth, G Biological Research Center of the Hungarian Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139011&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44376902 104028998 CHEMBL349738 ZINC27848856 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50255614 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C32H37N5O5/c33-25(18-23-13-15-24(38)16-14-23)32(42)37-17-7-12-28(37)31(41)36-27(20-22-10-5-2-6-11-22)30(40)35-26(29(34)39)19-21-8-3-1-4-9-21/h1-6,8-11,13-16,25-28,38H,7,12,17-20,33H2,(H2,34,39)(H,35,40)(H,36,41)/t25-,26-,27-,28-/m0/s1 XIJHWXXXIMEHKW-LJWNLINESA-N 50139013 (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::(S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxamide::1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylicacid[1-((S)-(S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL333357::H-Tyr-Pro-Phe-Phe-NH2::Tyr-Pro-Phe-Phe-NH2::endomorphin-2 Mu-type opioid receptor Cavia cutleri 9.22 ChEMBL 10.1021/jm0310028 10.7270/Q2J965TS 14736254 Tomboly, C; Kover, KE; Peter, A; Tourwe, D; Biyashev, D; Benyhe, S; Borsodi, A; Al-Khrasani, M; Ronai, AZ; Toth, G Biological Research Center of the Hungarian Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139013&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311081 104029000 CHEMBL333357 3668 ZINC14951634 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50255620 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C34H38N6O5/c35-26(17-22-12-14-24(41)15-13-22)34(45)40-16-6-11-30(40)33(44)39-29(19-23-20-37-27-10-5-4-9-25(23)27)32(43)38-28(31(36)42)18-21-7-2-1-3-8-21/h1-5,7-10,12-15,20,26,28-30,37,41H,6,11,16-19,35H2,(H2,36,42)(H,38,43)(H,39,44)/t26-,28-,29-,30-/m0/s1 ZEXLJFNSKAHNFH-SYKYGTKKSA-N 50095155 (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide::(S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxamide::1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [1-((S)-(S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide::1-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [1-(1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide::CHEMBL316446::ENDOMORPHIN-1::H-Tyr-Pro-Trp-Phe-NH2::Tyr-Pro-Trp-Phe-NH2::YPWF-NH2::endomorphin -1 Mu-type opioid receptor Cavia cutleri 10.1 ChEMBL 10.1021/jm0310028 10.7270/Q2J965TS 14736254 Tomboly, C; Kover, KE; Peter, A; Tourwe, D; Biyashev, D; Benyhe, S; Borsodi, A; Al-Khrasani, M; Ronai, AZ; Toth, G Biological Research Center of the Hungarian Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095155&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311080 103992914 CHEMBL316446 1623 ZINC14951658 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50255622 C[C@@H]([C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O)c1ccccc1 InChI=1S/C33H39N5O5/c1-21(24-11-6-3-7-12-24)29(30(35)40)37-31(41)27(20-22-9-4-2-5-10-22)36-32(42)28-13-8-18-38(28)33(43)26(34)19-23-14-16-25(39)17-15-23/h2-7,9-12,14-17,21,26-29,39H,8,13,18-20,34H2,1H3,(H2,35,40)(H,36,42)(H,37,41)/t21-,26+,27+,28+,29-/m1/s1 XEDWKSFZTLIHLE-VYTSZGCMSA-N 50139009 (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((1R,2R)-1-carbamoyl-2-phenyl-propylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL355141 Mu-type opioid receptor Cavia cutleri 816 ChEMBL 10.1021/jm0310028 10.7270/Q2J965TS 14736254 Tomboly, C; Kover, KE; Peter, A; Tourwe, D; Biyashev, D; Benyhe, S; Borsodi, A; Al-Khrasani, M; Ronai, AZ; Toth, G Biological Research Center of the Hungarian Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139009 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139009&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44377240 104028996 CHEMBL355141 ZINC27766163 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50276790 C[C@H](NC(=O)C1Cc2ccccc2CN1C(=O)C(N)Cc1c(C)cc(O)cc1C)C(N)=O InChI=1S/C24H30N4O4/c1-13-8-18(29)9-14(2)19(13)11-20(25)24(32)28-12-17-7-5-4-6-16(17)10-21(28)23(31)27-15(3)22(26)30/h4-9,15,20-21,29H,10-12,25H2,1-3H3,(H2,26,30)(H,27,31)/t15-,20?,21?/m0/s1 XLVQVCOZHAPLOB-VUZGARFFSA-N 50150797 2-[2-Amino-3-((S)-4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid (1-carbamoyl-ethyl)-amide::CHEMBL359786 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm040033f 10.7270/Q2P55N09 15267245 Balboni, G; Salvadori, S; Guerrini, R; Negri, L; Giannini, E; Bryant, SD; Jinsmaa, Y; Lazarus, LH University of Cagliary http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150797&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44396242 104039156 CHEMBL359786 ZINC28387297 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50276804 Cc1cc(O)cc(C)c1CC(N)C(=O)N1Cc2ccccc2CC1C(=O)NC(CO)C(O)=O InChI=1S/C24H29N3O6/c1-13-7-17(29)8-14(2)18(13)10-19(25)23(31)27-11-16-6-4-3-5-15(16)9-21(27)22(30)26-20(12-28)24(32)33/h3-8,19-21,28-29H,9-12,25H2,1-2H3,(H,26,30)(H,32,33) OALILIXRUGWOJN-UHFFFAOYSA-N 50150804 (R)-2-({2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-3-hydroxy-propionic acid::CHEMBL180594 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm040033f 10.7270/Q2P55N09 15267245 Balboni, G; Salvadori, S; Guerrini, R; Negri, L; Giannini, E; Bryant, SD; Jinsmaa, Y; Lazarus, LH University of Cagliary http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150804 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150804&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44393486 104039163 CHEMBL180594 ZINC28345529 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50276814 Cc1cc(O)cc(C)c1CC(N)C(=O)N1Cc2ccccc2CC1C(=O)NC(Cc1c[nH]c2ccccc12)C(O)=O InChI=1S/C32H34N4O5/c1-18-11-23(37)12-19(2)25(18)15-26(33)31(39)36-17-21-8-4-3-7-20(21)14-29(36)30(38)35-28(32(40)41)13-22-16-34-27-10-6-5-9-24(22)27/h3-12,16,26,28-29,34,37H,13-15,17,33H2,1-2H3,(H,35,38)(H,40,41) XWBHIDKWXAKDNX-UHFFFAOYSA-N 50150807 (R)-2-({2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-3-(1H-indol-3-yl)-propionic acid::CHEMBL185359 Mu-type opioid receptor Cavia cutleri 1500 ChEMBL 10.1021/jm040033f 10.7270/Q2P55N09 15267245 Balboni, G; Salvadori, S; Guerrini, R; Negri, L; Giannini, E; Bryant, SD; Jinsmaa, Y; Lazarus, LH University of Cagliary http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150807&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44393505 104039166 CHEMBL185359 ZINC28375489 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50276819 C[C@@H](NC(=O)C1Cc2ccccc2CN1C(=O)C(N)Cc1c(C)cc(O)cc1C)C(N)=O InChI=1S/C24H30N4O4/c1-13-8-18(29)9-14(2)19(13)11-20(25)24(32)28-12-17-7-5-4-6-16(17)10-21(28)23(31)27-15(3)22(26)30/h4-9,15,20-21,29H,10-12,25H2,1-3H3,(H2,26,30)(H,27,31)/t15-,20?,21?/m1/s1 XLVQVCOZHAPLOB-TVRCVXMWSA-N 50150805 2-[2-Amino-3-((R)-4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid (1-carbamoyl-ethyl)-amide::CHEMBL186457 Mu-type opioid receptor Cavia cutleri 4740 ChEMBL 10.1021/jm040033f 10.7270/Q2P55N09 15267245 Balboni, G; Salvadori, S; Guerrini, R; Negri, L; Giannini, E; Bryant, SD; Jinsmaa, Y; Lazarus, LH University of Cagliary http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150805&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44396221 104039164 CHEMBL186457 ZINC28455711 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50276823 Cc1cc(O)cc(C)c1CC(N)C(=O)N1Cc2ccccc2CC1C(=O)NC(CO)C(N)=O InChI=1S/C24H30N4O5/c1-13-7-17(30)8-14(2)18(13)10-19(25)24(33)28-11-16-6-4-3-5-15(16)9-21(28)23(32)27-20(12-29)22(26)31/h3-8,19-21,29-30H,9-12,25H2,1-2H3,(H2,26,31)(H,27,32) AFNRQBXHTFGQNH-UHFFFAOYSA-N 50150806 2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid ((R)-1-carbamoyl-2-hydroxy-ethyl)-amide::CHEMBL433951 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm040033f 10.7270/Q2P55N09 15267245 Balboni, G; Salvadori, S; Guerrini, R; Negri, L; Giannini, E; Bryant, SD; Jinsmaa, Y; Lazarus, LH University of Cagliary http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150806&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44393527 104039165 CHEMBL433951 ZINC28365836 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50276824 Cc1cc(O)cc(C)c1CC(N)C(=O)N1Cc2ccccc2CC1C(=O)NC(CCCNC(N)=N)C(N)=O InChI=1S/C27H37N7O4/c1-15-10-19(35)11-16(2)20(15)13-21(28)26(38)34-14-18-7-4-3-6-17(18)12-23(34)25(37)33-22(24(29)36)8-5-9-32-27(30)31/h3-4,6-7,10-11,21-23,35H,5,8-9,12-14,28H2,1-2H3,(H2,29,36)(H,33,37)(H4,30,31,32) QEHLFBPFXMYDCC-UHFFFAOYSA-N 50150802 2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid ((R)-1-carbamoyl-4-guanidino-butyl)-amide::CHEMBL185261 Mu-type opioid receptor Cavia cutleri 6600 ChEMBL 10.1021/jm040033f 10.7270/Q2P55N09 15267245 Balboni, G; Salvadori, S; Guerrini, R; Negri, L; Giannini, E; Bryant, SD; Jinsmaa, Y; Lazarus, LH University of Cagliary http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150802&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44393432 104039161 CHEMBL185261 ZINC28372024 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50276834 Cc1cc(O)cc(C)c1CC(N)C(=O)N1Cc2ccccc2CC1C(=O)NC(CCCCN)C(N)=O InChI=1S/C27H37N5O4/c1-16-11-20(33)12-17(2)21(16)14-22(29)27(36)32-15-19-8-4-3-7-18(19)13-24(32)26(35)31-23(25(30)34)9-5-6-10-28/h3-4,7-8,11-12,22-24,33H,5-6,9-10,13-15,28-29H2,1-2H3,(H2,30,34)(H,31,35) BGQXPCOJBYLICJ-UHFFFAOYSA-N 50150799 2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid ((R)-5-amino-1-carbamoyl-pentyl)-amide::CHEMBL182720 Mu-type opioid receptor Cavia cutleri 7870 ChEMBL 10.1021/jm040033f 10.7270/Q2P55N09 15267245 Balboni, G; Salvadori, S; Guerrini, R; Negri, L; Giannini, E; Bryant, SD; Jinsmaa, Y; Lazarus, LH University of Cagliary http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150799&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44393452 104039158 CHEMBL182720 ZINC28362177 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50276843 C[C@@H](NC(=O)C1Cc2ccccc2CN1C(=O)C(N)Cc1c(C)cc(O)cc1C)C(O)=O InChI=1S/C24H29N3O5/c1-13-8-18(28)9-14(2)19(13)11-20(25)23(30)27-12-17-7-5-4-6-16(17)10-21(27)22(29)26-15(3)24(31)32/h4-9,15,20-21,28H,10-12,25H2,1-3H3,(H,26,29)(H,31,32)/t15-,20?,21?/m1/s1 TUXLEAJGNKFQRS-TVRCVXMWSA-N 50150809 2-({2-[2-Amino-3-((R)-4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-propionic acid::CHEMBL189511 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm040033f 10.7270/Q2P55N09 15267245 Balboni, G; Salvadori, S; Guerrini, R; Negri, L; Giannini, E; Bryant, SD; Jinsmaa, Y; Lazarus, LH University of Cagliary http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150809&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44396231 104039168 CHEMBL189511 ZINC26832201 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50276844 Cc1cc(O)cc(C)c1CC(N)C(=O)N1Cc2ccccc2CC1C(=O)NCC(N)=O InChI=1S/C23H28N4O4/c1-13-7-17(28)8-14(2)18(13)10-19(24)23(31)27-12-16-6-4-3-5-15(16)9-20(27)22(30)26-11-21(25)29/h3-8,19-20,28H,9-12,24H2,1-2H3,(H2,25,29)(H,26,30) BNLSEGXVNPKOOA-UHFFFAOYSA-N 50150798 2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid ((R)-carbamoylmethyl)-amide::CHEMBL185199 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm040033f 10.7270/Q2P55N09 15267245 Balboni, G; Salvadori, S; Guerrini, R; Negri, L; Giannini, E; Bryant, SD; Jinsmaa, Y; Lazarus, LH University of Cagliary http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150798&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44393460 104039157 CHEMBL185199 ZINC28374623 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50276847 Cc1cc(O)cc(C)c1CC(N)C(=O)N1Cc2ccccc2CC1C(=O)NC(Cc1cnc[nH]1)C(O)=O InChI=1S/C27H31N5O5/c1-15-7-20(33)8-16(2)21(15)11-22(28)26(35)32-13-18-6-4-3-5-17(18)9-24(32)25(34)31-23(27(36)37)10-19-12-29-14-30-19/h3-8,12,14,22-24,33H,9-11,13,28H2,1-2H3,(H,29,30)(H,31,34)(H,36,37) TYUGMMOCSRYPGE-UHFFFAOYSA-N 50150810 (R)-2-({2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-3-(1H-imidazol-4-yl)-propionic acid::CHEMBL184875 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm040033f 10.7270/Q2P55N09 15267245 Balboni, G; Salvadori, S; Guerrini, R; Negri, L; Giannini, E; Bryant, SD; Jinsmaa, Y; Lazarus, LH University of Cagliary http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150810 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150810&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44393466 104039169 CHEMBL184875 ZINC28371916 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50273273 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)Cc1cccnc41)ccc5O InChI=1S/C20H20N2O3/c1-22-8-6-19-15-11-4-5-13(23)17(15)25-18(19)16-12(3-2-7-21-16)10-20(19,24)14(22)9-11/h2-5,7,14,18,23-24H,6,8-10H2,1H3/t14-,18+,19+,20-/m1/s1 BMECSLWZPCVUJH-QRKUABHPSA-N 50048106 CHEMBL611435 Mu-type opioid receptor Cavia cutleri 523 ChEMBL 10.1016/j.bmc.2014.05.065 10.7270/Q2JM2C8P 24973818 Kumar, V; Clark, MJ; Traynor, JR; Lewis, JW; Husbands, SM University of Bath http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048106 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048106&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11359624 103978639 CHEMBL611435 ZINC29556910 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50278867 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H]1CSSC[C@@H](NC(=O)[C@H](Cc2ccc(cc2)[N+]([O-])=O)NC(=O)CNC1=O)C(N)=O InChI=1S/C28H35N7O8S2/c1-14-7-18(36)8-15(2)19(14)10-20(29)26(39)34-23-13-45-44-12-22(25(30)38)33-28(41)21(32-24(37)11-31-27(23)40)9-16-3-5-17(6-4-16)35(42)43/h3-8,20-23,36H,9-13,29H2,1-2H3,(H2,30,38)(H,31,40)(H,32,37)(H,33,41)(H,34,39)/t20-,21-,22+,23-/m0/s1 NLNQRXBCJMAZFC-GPJHCHHRSA-N 50151753 1N-[6-carbamoyl-9-(4-nitrobenzyl)-8,11,14-trioxo-(1R,6S,9S)-3,4-dithia-7,10,13-triazacyclotetradecanyl]-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-(2S)-propanamide::CHEMBL184009 Mu-type opioid receptor Cavia cutleri 0.540000 ChEMBL 10.1016/j.bmcl.2004.06.077 10.7270/Q2610ZR8 15324897 Weltrowska, G; Lu, Y; Lemieux, C; Chung, NN; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151753 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151753&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44393900 104039910 CHEMBL184009 ZINC28378047 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50293270 Cc1cc(O)c(C)c(C)c1CC(N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C35H43N5O5/c1-21-17-31(41)23(3)22(2)26(21)20-27(36)35(45)40-16-10-15-30(40)34(44)39-29(19-25-13-8-5-9-14-25)33(43)38-28(32(37)42)18-24-11-6-4-7-12-24/h4-9,11-14,17,27-30,41H,10,15-16,18-20,36H2,1-3H3,(H2,37,42)(H,38,43)(H,39,44)/t27?,28-,29-,30-/m0/s1 BDMYIPNSEIOOMG-UOOFWSDHSA-N 50159680 (S)-1-[2-Amino-3-(4-hydroxy-2,3,6-trimethyl-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL179246 Mu-type opioid receptor Cavia cutleri 2.31 ChEMBL 10.1021/jm049384k 10.7270/Q26T0M40 15658871 Li, T; Fujita, Y; Tsuda, Y; Miyazaki, A; Ambo, A; Sasaki, Y; Jinsmaa, Y; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159680&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44388171 104046107 CHEMBL179246 ZINC28117644 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50293272 CCc1cc(O)cc(C)c1CC(N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C35H43N5O5/c1-3-25-20-26(41)17-22(2)27(25)21-28(36)35(45)40-16-10-15-31(40)34(44)39-30(19-24-13-8-5-9-14-24)33(43)38-29(32(37)42)18-23-11-6-4-7-12-23/h4-9,11-14,17,20,28-31,41H,3,10,15-16,18-19,21,36H2,1-2H3,(H2,37,42)(H,38,43)(H,39,44)/t28?,29-,30-,31-/m0/s1 BZLYBGIVFPHHKD-BQFSGGQZSA-N 50159681 (S)-1-[2-Amino-3-(2-ethyl-4-hydroxy-6-methyl-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL175770 Mu-type opioid receptor Cavia cutleri 0.623 ChEMBL 10.1021/jm049384k 10.7270/Q26T0M40 15658871 Li, T; Fujita, Y; Tsuda, Y; Miyazaki, A; Ambo, A; Sasaki, Y; Jinsmaa, Y; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159681 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159681&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44387958 104046108 CHEMBL175770 ZINC28113983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50293276 Cc1cc(O)ccc1CC(N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C33H39N5O5/c1-21-17-25(39)15-14-24(21)20-26(34)33(43)38-16-8-13-29(38)32(42)37-28(19-23-11-6-3-7-12-23)31(41)36-27(30(35)40)18-22-9-4-2-5-10-22/h2-7,9-12,14-15,17,26-29,39H,8,13,16,18-20,34H2,1H3,(H2,35,40)(H,36,41)(H,37,42)/t26?,27-,28-,29-/m0/s1 ZPYMRXNXCMOBIW-LJTAYKMUSA-N 50159682 (S)-1-[2-Amino-3-(4-hydroxy-2-methyl-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL367068 Mu-type opioid receptor Cavia cutleri 0.924 ChEMBL 10.1021/jm049384k 10.7270/Q26T0M40 15658871 Li, T; Fujita, Y; Tsuda, Y; Miyazaki, A; Ambo, A; Sasaki, Y; Jinsmaa, Y; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159682 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159682&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44387957 104046109 CHEMBL367068 ZINC28116346 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50293278 CC(C)c1cc(O)cc(C(C)C)c1CC(N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C38H49N5O5/c1-23(2)28-20-27(44)21-29(24(3)4)30(28)22-31(39)38(48)43-17-11-16-34(43)37(47)42-33(19-26-14-9-6-10-15-26)36(46)41-32(35(40)45)18-25-12-7-5-8-13-25/h5-10,12-15,20-21,23-24,31-34,44H,11,16-19,22,39H2,1-4H3,(H2,40,45)(H,41,46)(H,42,47)/t31?,32-,33-,34-/m0/s1 HYGLBIKRQLUOBU-GSSGUZCNSA-N 50159683 (S)-1-[2-Amino-3-(4-hydroxy-2,6-diisopropyl-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL361381 Mu-type opioid receptor Cavia cutleri 299 ChEMBL 10.1021/jm049384k 10.7270/Q26T0M40 15658871 Li, T; Fujita, Y; Tsuda, Y; Miyazaki, A; Ambo, A; Sasaki, Y; Jinsmaa, Y; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159683&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44388170 104046110 CHEMBL361381 ZINC28117614 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50293288 CC(C)c1cc(O)cc(C)c1CC(N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C36H45N5O5/c1-22(2)27-20-26(42)17-23(3)28(27)21-29(37)36(46)41-16-10-15-32(41)35(45)40-31(19-25-13-8-5-9-14-25)34(44)39-30(33(38)43)18-24-11-6-4-7-12-24/h4-9,11-14,17,20,22,29-32,42H,10,15-16,18-19,21,37H2,1-3H3,(H2,38,43)(H,39,44)(H,40,45)/t29?,30-,31-,32-/m0/s1 CLVKKUURJFCWPP-PTMYVKAOSA-N 50159686 (S)-1-[2-Amino-3-(4-hydroxy-2-isopropyl-6-methyl-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL361598 Mu-type opioid receptor Cavia cutleri 10.6 ChEMBL 10.1021/jm049384k 10.7270/Q26T0M40 15658871 Li, T; Fujita, Y; Tsuda, Y; Miyazaki, A; Ambo, A; Sasaki, Y; Jinsmaa, Y; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159686&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44388159 104046113 CHEMBL361598 ZINC28116985 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50293289 CCc1cc(O)cc(CC)c1CC(N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C36H45N5O5/c1-3-25-20-27(42)21-26(4-2)28(25)22-29(37)36(46)41-17-11-16-32(41)35(45)40-31(19-24-14-9-6-10-15-24)34(44)39-30(33(38)43)18-23-12-7-5-8-13-23/h5-10,12-15,20-21,29-32,42H,3-4,11,16-19,22,37H2,1-2H3,(H2,38,43)(H,39,44)(H,40,45)/t29?,30-,31-,32-/m0/s1 GRIMHILSJHZLCF-PTMYVKAOSA-N 50159684 (S)-1-[2-Amino-3-(2,6-diethyl-4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL362002 Mu-type opioid receptor Cavia cutleri 0.903 ChEMBL 10.1021/jm049384k 10.7270/Q26T0M40 15658871 Li, T; Fujita, Y; Tsuda, Y; Miyazaki, A; Ambo, A; Sasaki, Y; Jinsmaa, Y; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159684 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159684&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44388160 104046111 CHEMBL362002 ZINC28117543 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50293291 Cc1cc(C[C@H](N)C(=O)N2CCCC2C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)c(C)cc1O InChI=1S/C34H41N5O5/c1-21-17-30(40)22(2)16-25(21)20-26(35)34(44)39-15-9-14-29(39)33(43)38-28(19-24-12-7-4-8-13-24)32(42)37-27(31(36)41)18-23-10-5-3-6-11-23/h3-8,10-13,16-17,26-29,40H,9,14-15,18-20,35H2,1-2H3,(H2,36,41)(H,37,42)(H,38,43)/t26-,27-,28-,29?/m0/s1 JKBSAZRICCYEQM-QNKVVAGZSA-N 50159685 5N-[1-[1-carbamoyl-2-phenyl-(1S)-ethylcarbamoyl]-2-phenyl-(1S)-ethyl]-1-[2-amino-3-(4-hydroxy-2,5-dimethylphenyl)-(2S)-propanoyl]-(5S)-dihydro-1H-5-pyrrolecarboxamide::CHEMBL367635 Mu-type opioid receptor Cavia cutleri 0.261 ChEMBL 10.1021/jm049384k 10.7270/Q26T0M40 15658871 Li, T; Fujita, Y; Tsuda, Y; Miyazaki, A; Ambo, A; Sasaki, Y; Jinsmaa, Y; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159685 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159685&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44388185 104046112 CHEMBL367635 ZINC28109957 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50289571 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)N[C@@H](CCC(O)=O)C(=O)NCCCCCN InChI=1S/C31H43N5O6/c1-19-14-23(37)15-20(2)24(19)17-25(33)31(42)36-18-22-9-5-4-8-21(22)16-27(36)30(41)35-26(10-11-28(38)39)29(40)34-13-7-3-6-12-32/h4-5,8-9,14-15,25-27,37H,3,6-7,10-13,16-18,32-33H2,1-2H3,(H,34,40)(H,35,41)(H,38,39)/t25-,26-,27?/m0/s1 JKBJCPFUZMWEMK-TXIPYEPDSA-N 50157685 CHEMBL225479::H-Dmt-Tic-Glu-NH-(CH2)5-NH2 Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm040128h 10.7270/Q28W3CS2 15588089 Balboni, G; Salvadori, S; Dal Piaz, A; Bortolotti, F; Argazzi, R; Negri, L; Lattanzi, R; Bryant, SD; Jinsmaa, Y; Lazarus, LH University of Cagliary http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50157685 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50157685&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44421433 104044608 CHEMBL225479 ZINC28639192 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50289572 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)N[C@@H](CCC(O)=O)C(=O)NCCCCCNC(=S)Nc1ccc(c(c1)C(O)=O)-c1c2ccc(O)cc2oc2cc(=O)ccc12 InChI=1S/C52H54N6O11S/c1-28-20-35(61)21-29(2)39(28)26-41(53)50(66)58-27-31-9-5-4-8-30(31)22-43(58)49(65)57-42(16-17-46(62)63)48(64)54-18-6-3-7-19-55-52(70)56-32-10-13-36(40(23-32)51(67)68)47-37-14-11-33(59)24-44(37)69-45-25-34(60)12-15-38(45)47/h4-5,8-15,20-21,23-25,41-43,59,61H,3,6-7,16-19,22,26-27,53H2,1-2H3,(H,54,64)(H,57,65)(H,62,63)(H,67,68)(H2,55,56,70)/t41-,42-,43?/m0/s1 DUTHHZUJFXVHNS-PIGVCAKBSA-N 50157686 5-[({5-[(2S)-2-({2-[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]-1,2,3,4-tetrahydroisoquinolin-3-yl}formamido)-4-carboxybutanamido]pentyl}carbamothioyl)amino]-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid::CHEMBL388320 Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm040128h 10.7270/Q28W3CS2 15588089 Balboni, G; Salvadori, S; Dal Piaz, A; Bortolotti, F; Argazzi, R; Negri, L; Lattanzi, R; Bryant, SD; Jinsmaa, Y; Lazarus, LH University of Cagliary http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50157686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50157686&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44421434 104044609 CHEMBL388320 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50289575 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](CCC(O)=O)C(N)=O InChI=1S/C26H32N4O6/c1-14-9-18(31)10-15(2)19(14)12-20(27)26(36)30-13-17-6-4-3-5-16(17)11-22(30)25(35)29-21(24(28)34)7-8-23(32)33/h3-6,9-10,20-22,31H,7-8,11-13,27H2,1-2H3,(H2,28,34)(H,29,35)(H,32,33)/t20-,21-,22-/m0/s1 CXJVHAFXBCEOKB-FKBYEOEOSA-N 50157684 CHEMBL2369958::H-Dmt-Tic-Glu-NH2 Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm040128h 10.7270/Q28W3CS2 15588089 Balboni, G; Salvadori, S; Dal Piaz, A; Bortolotti, F; Argazzi, R; Negri, L; Lattanzi, R; Bryant, SD; Jinsmaa, Y; Lazarus, LH University of Cagliary http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50157684 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50157684&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11156202 104044607 CHEMBL2369958 ZINC28375025 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50302688 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C46H53N7O8/c47-35(25-31-15-19-33(54)20-16-31)45(60)52-23-7-13-39(52)44(59)50-37(27-30-11-5-2-6-12-30)42(57)51-38(28-32-17-21-34(55)22-18-32)46(61)53-24-8-14-40(53)43(58)49-36(41(48)56)26-29-9-3-1-4-10-29/h1-6,9-12,15-22,35-40,54-55H,7-8,13-14,23-28,47H2,(H2,48,56)(H,49,58)(H,50,59)(H,51,57)/t35-,36-,37-,38-,39-,40-/m0/s1 PMYWZDRRZPJWHV-UNHORJANSA-N 50163908 CHEMBL179946::[Tyr-Pro-Phe-NH-]2 Mu-type opioid receptor Cavia cutleri 1135 ChEMBL 10.1016/j.bmcl.2005.02.021 10.7270/Q2571BHT 15780619 Gao, Y; Liu, X; Wei, J; Zhu, B; Chen, Q; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163908 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163908&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44390663 104049834 CHEMBL179946 ZINC95606490 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50302699 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C32H37N5O5/c33-25(18-23-13-15-24(38)16-14-23)32(42)37-17-7-12-28(37)31(41)36-27(20-22-10-5-2-6-11-22)30(40)35-26(29(34)39)19-21-8-3-1-4-9-21/h1-6,8-11,13-16,25-28,38H,7,12,17-20,33H2,(H2,34,39)(H,35,40)(H,36,41)/t25-,26-,27-,28-/m0/s1 XIJHWXXXIMEHKW-LJWNLINESA-N 50139013 (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::(S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxamide::1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylicacid[1-((S)-(S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL333357::H-Tyr-Pro-Phe-Phe-NH2::Tyr-Pro-Phe-Phe-NH2::endomorphin-2 Mu-type opioid receptor Cavia cutleri 14.7 ChEMBL 10.1016/j.bmcl.2005.02.021 10.7270/Q2571BHT 15780619 Gao, Y; Liu, X; Wei, J; Zhu, B; Chen, Q; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139013&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311081 104029000 CHEMBL333357 3668 ZINC14951634 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50302709 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)CCN[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C66H75N9O10/c67-51(37-47-25-29-49(76)30-26-47)65(84)74-35-13-23-57(74)63(82)72-54(40-45-19-9-3-10-20-45)61(80)70-52(38-43-15-5-1-6-16-43)59(78)33-34-69-56(42-48-27-31-50(77)32-28-48)66(85)75-36-14-24-58(75)64(83)73-55(41-46-21-11-4-12-22-46)62(81)71-53(60(68)79)39-44-17-7-2-8-18-44/h1-12,15-22,25-32,51-58,69,76-77H,13-14,23-24,33-42,67H2,(H2,68,79)(H,70,80)(H,71,81)(H,72,82)(H,73,83)/t51-,52-,53-,54-,55-,56-,57-,58-/m0/s1 YHWMMBKGEDGQFW-LEPIMFGVSA-N 50163910 CHEMBL409336::[Tyr-Pro-Phe-Phe-NH-CH2-]2 Mu-type opioid receptor Cavia cutleri 3544 ChEMBL 10.1016/j.bmcl.2005.02.021 10.7270/Q2571BHT 15780619 Gao, Y; Liu, X; Wei, J; Zhu, B; Chen, Q; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163910 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163910&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44390629 104049836 CHEMBL409336 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50302711 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)CCN[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C48H57N7O8/c49-37(27-33-15-19-35(56)20-16-33)47(62)54-25-7-13-41(54)45(60)52-38(28-31-9-3-1-4-10-31)43(58)23-24-51-40(30-34-17-21-36(57)22-18-34)48(63)55-26-8-14-42(55)46(61)53-39(44(50)59)29-32-11-5-2-6-12-32/h1-6,9-12,15-22,37-42,51,56-57H,7-8,13-14,23-30,49H2,(H2,50,59)(H,52,60)(H,53,61)/t37-,38-,39-,40-,41-,42-/m0/s1 SDEZJRFUZMVTCN-UJKKYYSESA-N 50163914 CHEMBL180286::[Tyr-Pro-Phe-NH-CH2-]2 Mu-type opioid receptor Cavia cutleri 218 ChEMBL 10.1016/j.bmcl.2005.02.021 10.7270/Q2571BHT 15780619 Gao, Y; Liu, X; Wei, J; Zhu, B; Chen, Q; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163914&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44390664 104049840 CHEMBL180286 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50302712 COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C33H38N4O6/c1-43-33(42)28(21-23-11-6-3-7-12-23)36-30(39)27(20-22-9-4-2-5-10-22)35-31(40)29-13-8-18-37(29)32(41)26(34)19-24-14-16-25(38)17-15-24/h2-7,9-12,14-17,26-29,38H,8,13,18-21,34H2,1H3,(H,35,40)(H,36,39)/t26-,27-,28-,29-/m0/s1 YYNCXEIEPLRPCR-DZUOILHNSA-N 50163909 CHEMBL361922::Tyr-Pro-Phe-Phe-OCH3::Tyr-Pro-Phe-Phe-OMe Mu-type opioid receptor Cavia cutleri 42.1 ChEMBL 10.1016/j.bmcl.2005.02.021 10.7270/Q2571BHT 15780619 Gao, Y; Liu, X; Wei, J; Zhu, B; Chen, Q; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163909 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163909&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44390652 104049835 CHEMBL361922 ZINC28333815 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50302718 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C64H71N9O10/c65-49(35-45-25-29-47(74)30-26-45)63(82)72-33-13-23-55(72)61(80)70-53(39-44-21-11-4-12-22-44)59(78)68-51(37-42-17-7-2-8-18-42)60(79)71-54(40-46-27-31-48(75)32-28-46)64(83)73-34-14-24-56(73)62(81)69-52(38-43-19-9-3-10-20-43)58(77)67-50(57(66)76)36-41-15-5-1-6-16-41/h1-12,15-22,25-32,49-56,74-75H,13-14,23-24,33-40,65H2,(H2,66,76)(H,67,77)(H,68,78)(H,69,81)(H,70,80)(H,71,79)/t49-,50-,51-,52-,53-,54-,55-,56-/m0/s1 DEEQOLBYTQLJHH-MENCHSDRSA-N 50163911 CHEMBL386887::[Tyr-Pro-Phe-Phe-NH-]2 Mu-type opioid receptor Cavia cutleri 518 ChEMBL 10.1016/j.bmcl.2005.02.021 10.7270/Q2571BHT 15780619 Gao, Y; Liu, X; Wei, J; Zhu, B; Chen, Q; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163911 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163911&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44390628 104049837 CHEMBL386887 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50302720 NNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C32H38N6O5/c33-25(18-23-13-15-24(39)16-14-23)32(43)38-17-7-12-28(38)31(42)36-26(19-21-8-3-1-4-9-21)29(40)35-27(30(41)37-34)20-22-10-5-2-6-11-22/h1-6,8-11,13-16,25-28,39H,7,12,17-20,33-34H2,(H,35,40)(H,36,42)(H,37,41)/t25-,26-,27-,28-/m0/s1 JZSLBNUKUIAYPN-LJWNLINESA-N 50163913 CHEMBL180777::Tyr-Pro-Phe-Phe-NHNH2 Mu-type opioid receptor Cavia cutleri 132 ChEMBL 10.1016/j.bmcl.2005.02.021 10.7270/Q2571BHT 15780619 Gao, Y; Liu, X; Wei, J; Zhu, B; Chen, Q; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163913 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163913&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 24857892 104049839 CHEMBL180777 ZINC28332726 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50310048 CN(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)CN1Cc2ccccc2C[C@H](NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C1=O InChI=1S/C39H46F6N8O5/c1-21-11-28(54)12-22(2)29(21)17-30(46)34(56)50-31(9-6-10-49-37(47)48)35(57)51-32-15-24-7-4-5-8-25(24)19-53(36(32)58)20-33(55)52(3)18-23-13-26(38(40,41)42)16-27(14-23)39(43,44)45/h4-5,7-8,11-14,16,30-32,54H,6,9-10,15,17-20,46H2,1-3H3,(H,50,56)(H,51,57)(H4,47,48,49)/t30-,31+,32-/m0/s1 UXNDGPPTVKDIOD-QAXCHELISA-N 50346329 (R)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)-N-((S)-2-(2-((3,5-bis(trifluoromethyl)benzyl)(methyl)amino)-2-oxoethyl)-3-oxo-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-yl)-5-guanidinopentanamide::CHEMBL1782141 Mu-type opioid receptor Cavia cutleri 8.5 ChEMBL 10.1016/j.ejmech.2014.12.033 10.7270/Q2M90BCC 25544687 Guillemyn, K; Kleczkowska, P; Lesniak, A; Dyniewicz, J; Van der Poorten, O; Van den Eynde, I; Keresztes, A; Varga, E; Lai, J; Porreca, F; Chung, NN; Lemieux, C; Mika, J; Rojewska, E; Makuch, W; Van Duppen, J; Przewlocka, B; Vanden Broeck, J; Lipkowski, AW; Schiller, PW; Tourwé, D; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346329 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346329&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 52937467 131349260 CHEMBL1782141 ZINC95548072 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50310049 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H]1Cc2ccccc2CN(CC(N)=O)C1=O InChI=1S/C29H40N8O5/c1-16-10-20(38)11-17(2)21(16)13-22(30)26(40)35-23(8-5-9-34-29(32)33)27(41)36-24-12-18-6-3-4-7-19(18)14-37(28(24)42)15-25(31)39/h3-4,6-7,10-11,22-24,38H,5,8-9,12-15,30H2,1-2H3,(H2,31,39)(H,35,40)(H,36,41)(H4,32,33,34)/t22-,23+,24-/m0/s1 ORYLQLGPWPORPN-VXNXHJTFSA-N 50346330 (R)-N-((S)-2-(2-amino-2-oxoethyl)-3-oxo-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-yl)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)-5-guanidinopentanamide::CHEMBL1782140 Mu-type opioid receptor Cavia cutleri 0.320000 ChEMBL 10.1016/j.ejmech.2014.12.033 10.7270/Q2M90BCC 25544687 Guillemyn, K; Kleczkowska, P; Lesniak, A; Dyniewicz, J; Van der Poorten, O; Van den Eynde, I; Keresztes, A; Varga, E; Lai, J; Porreca, F; Chung, NN; Lemieux, C; Mika, J; Rojewska, E; Makuch, W; Van Duppen, J; Przewlocka, B; Vanden Broeck, J; Lipkowski, AW; Schiller, PW; Tourwé, D; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346330&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 52937468 131349261 CHEMBL1782140 ZINC71295052 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50310050 CN(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)CCN1Cc2ccccc2C[C@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C1=O InChI=1S/C40H48F6N8O5/c1-22-13-29(55)14-23(2)30(22)19-31(47)35(57)51-32(9-6-11-50-38(48)49)36(58)52-33-17-25-7-4-5-8-26(25)21-54(37(33)59)12-10-34(56)53(3)20-24-15-27(39(41,42)43)18-28(16-24)40(44,45)46/h4-5,7-8,13-16,18,31-33,55H,6,9-12,17,19-21,47H2,1-3H3,(H,51,57)(H,52,58)(H4,48,49,50)/t31-,32+,33-/m0/s1 ZVPJBYZIHCWVQP-DSPMFFIESA-N 50070376 CHEMBL3408518 Mu-type opioid receptor Cavia cutleri 11 ChEMBL 10.1016/j.ejmech.2014.12.033 10.7270/Q2M90BCC 25544687 Guillemyn, K; Kleczkowska, P; Lesniak, A; Dyniewicz, J; Van der Poorten, O; Van den Eynde, I; Keresztes, A; Varga, E; Lai, J; Porreca, F; Chung, NN; Lemieux, C; Mika, J; Rojewska, E; Makuch, W; Van Duppen, J; Przewlocka, B; Vanden Broeck, J; Lipkowski, AW; Schiller, PW; Tourwé, D; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070376 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070376&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 118730932 313072392 CHEMBL3408518 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50310051 CN(Cc1ccccc1)C(=O)CCN1Cc2ccccc2C[C@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C1=O InChI=1S/C38H50N8O5/c1-24-18-29(47)19-25(2)30(24)21-31(39)35(49)43-32(14-9-16-42-38(40)41)36(50)44-33-20-27-12-7-8-13-28(27)23-46(37(33)51)17-15-34(48)45(3)22-26-10-5-4-6-11-26/h4-8,10-13,18-19,31-33,47H,9,14-17,20-23,39H2,1-3H3,(H,43,49)(H,44,50)(H4,40,41,42)/t31-,32+,33-/m0/s1 JREBGRHWCUPUKA-DSPMFFIESA-N 50070377 CHEMBL3408519 Mu-type opioid receptor Cavia cutleri 1.9 ChEMBL 10.1016/j.ejmech.2014.12.033 10.7270/Q2M90BCC 25544687 Guillemyn, K; Kleczkowska, P; Lesniak, A; Dyniewicz, J; Van der Poorten, O; Van den Eynde, I; Keresztes, A; Varga, E; Lai, J; Porreca, F; Chung, NN; Lemieux, C; Mika, J; Rojewska, E; Makuch, W; Van Duppen, J; Przewlocka, B; Vanden Broeck, J; Lipkowski, AW; Schiller, PW; Tourwé, D; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070377 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070377&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 118730933 313072393 CHEMBL3408519 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50310052 CN(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)CCN1Cc2ccccc2C[C@H](NC(=O)[C@@H](CCCNC(N)=O)NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C1=O InChI=1S/C40H47F6N7O6/c1-22-13-29(54)14-23(2)30(22)19-31(47)35(56)50-32(9-6-11-49-38(48)59)36(57)51-33-17-25-7-4-5-8-26(25)21-53(37(33)58)12-10-34(55)52(3)20-24-15-27(39(41,42)43)18-28(16-24)40(44,45)46/h4-5,7-8,13-16,18,31-33,54H,6,9-12,17,19-21,47H2,1-3H3,(H,50,56)(H,51,57)(H3,48,49,59)/t31-,32+,33-/m0/s1 NYBRMXDKXYPGRK-DSPMFFIESA-N 50070378 CHEMBL3408520 Mu-type opioid receptor Cavia cutleri 2.0 ChEMBL 10.1016/j.ejmech.2014.12.033 10.7270/Q2M90BCC 25544687 Guillemyn, K; Kleczkowska, P; Lesniak, A; Dyniewicz, J; Van der Poorten, O; Van den Eynde, I; Keresztes, A; Varga, E; Lai, J; Porreca, F; Chung, NN; Lemieux, C; Mika, J; Rojewska, E; Makuch, W; Van Duppen, J; Przewlocka, B; Vanden Broeck, J; Lipkowski, AW; Schiller, PW; Tourwé, D; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070378 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070378&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 118730934 313072394 CHEMBL3408520 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50310053 CN(Cc1ccccc1)C(=O)CCN1Cc2ccccc2C[C@H](NC(=O)[C@@H](CCCNC(N)=O)NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C1=O InChI=1S/C38H49N7O6/c1-24-18-29(46)19-25(2)30(24)21-31(39)35(48)42-32(14-9-16-41-38(40)51)36(49)43-33-20-27-12-7-8-13-28(27)23-45(37(33)50)17-15-34(47)44(3)22-26-10-5-4-6-11-26/h4-8,10-13,18-19,31-33,46H,9,14-17,20-23,39H2,1-3H3,(H,42,48)(H,43,49)(H3,40,41,51)/t31-,32+,33-/m0/s1 WWUPAOQRBLVDHW-DSPMFFIESA-N 50070379 CHEMBL3408521 Mu-type opioid receptor Cavia cutleri 0.960000 ChEMBL 10.1016/j.ejmech.2014.12.033 10.7270/Q2M90BCC 25544687 Guillemyn, K; Kleczkowska, P; Lesniak, A; Dyniewicz, J; Van der Poorten, O; Van den Eynde, I; Keresztes, A; Varga, E; Lai, J; Porreca, F; Chung, NN; Lemieux, C; Mika, J; Rojewska, E; Makuch, W; Van Duppen, J; Przewlocka, B; Vanden Broeck, J; Lipkowski, AW; Schiller, PW; Tourwé, D; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070379 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070379&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 118730935 313072395 CHEMBL3408521 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50310054 CN(Cc1ccccc1)C(=O)CN1Cc2ccccc2C[C@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C1=O InChI=1S/C37H48N8O5/c1-23-16-28(46)17-24(2)29(23)19-30(38)34(48)42-31(14-9-15-41-37(39)40)35(49)43-32-18-26-12-7-8-13-27(26)21-45(36(32)50)22-33(47)44(3)20-25-10-5-4-6-11-25/h4-8,10-13,16-17,30-32,46H,9,14-15,18-22,38H2,1-3H3,(H,42,48)(H,43,49)(H4,39,40,41)/t30-,31+,32-/m0/s1 DXDAOPRJHIBOSF-QAXCHELISA-N 50070380 CHEMBL3408522 Mu-type opioid receptor Cavia cutleri 6.0 ChEMBL 10.1016/j.ejmech.2014.12.033 10.7270/Q2M90BCC 25544687 Guillemyn, K; Kleczkowska, P; Lesniak, A; Dyniewicz, J; Van der Poorten, O; Van den Eynde, I; Keresztes, A; Varga, E; Lai, J; Porreca, F; Chung, NN; Lemieux, C; Mika, J; Rojewska, E; Makuch, W; Van Duppen, J; Przewlocka, B; Vanden Broeck, J; Lipkowski, AW; Schiller, PW; Tourwé, D; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070380 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070380&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 118730936 313072396 CHEMBL3408522 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50310055 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H]1Cc2ccccc2CN(CC(=O)NCc2ccccc2)C1=O InChI=1S/C36H46N8O5/c1-22-15-27(45)16-23(2)28(22)18-29(37)33(47)42-30(13-8-14-40-36(38)39)34(48)43-31-17-25-11-6-7-12-26(25)20-44(35(31)49)21-32(46)41-19-24-9-4-3-5-10-24/h3-7,9-12,15-16,29-31,45H,8,13-14,17-21,37H2,1-2H3,(H,41,46)(H,42,47)(H,43,48)(H4,38,39,40)/t29-,30+,31-/m0/s1 UCCJAMQRFDRLBW-YPKYBTACSA-N 50070381 CHEMBL3408730 Mu-type opioid receptor Cavia cutleri 4.4 ChEMBL 10.1016/j.ejmech.2014.12.033 10.7270/Q2M90BCC 25544687 Guillemyn, K; Kleczkowska, P; Lesniak, A; Dyniewicz, J; Van der Poorten, O; Van den Eynde, I; Keresztes, A; Varga, E; Lai, J; Porreca, F; Chung, NN; Lemieux, C; Mika, J; Rojewska, E; Makuch, W; Van Duppen, J; Przewlocka, B; Vanden Broeck, J; Lipkowski, AW; Schiller, PW; Tourwé, D; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070381 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070381&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 118731113 313072397 CHEMBL3408730 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50310056 CN(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)CN(C)C(=O)C(Cc1ccccc1)NC(=O)C(CCCNC(N)=N)NC(=O)C(N)Cc1c(C)cc(O)cc1C InChI=1S/C39H48F6N8O5/c1-22-13-28(54)14-23(2)29(22)19-30(46)34(56)50-31(11-8-12-49-37(47)48)35(57)51-32(17-24-9-6-5-7-10-24)36(58)53(4)21-33(55)52(3)20-25-15-26(38(40,41)42)18-27(16-25)39(43,44)45/h5-7,9-10,13-16,18,30-32,54H,8,11-12,17,19-21,46H2,1-4H3,(H,50,56)(H,51,57)(H4,47,48,49) CMQPBJQRYACTFV-UHFFFAOYSA-N 50070384 CHEMBL3408735 Mu-type opioid receptor Cavia cutleri 3.0 ChEMBL 10.1016/j.ejmech.2014.12.033 10.7270/Q2M90BCC 25544687 Guillemyn, K; Kleczkowska, P; Lesniak, A; Dyniewicz, J; Van der Poorten, O; Van den Eynde, I; Keresztes, A; Varga, E; Lai, J; Porreca, F; Chung, NN; Lemieux, C; Mika, J; Rojewska, E; Makuch, W; Van Duppen, J; Przewlocka, B; Vanden Broeck, J; Lipkowski, AW; Schiller, PW; Tourwé, D; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070384 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070384&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 118731118 313072400 CHEMBL3408735 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50310057 CN(CC(=O)N(C)Cc1ccccc1)C(=O)C(Cc1ccccc1)NC(=O)C(CCCNC(N)=N)NC(=O)C(N)Cc1c(C)cc(O)cc1C InChI=1S/C37H50N8O5/c1-24-18-28(46)19-25(2)29(24)21-30(38)34(48)42-31(16-11-17-41-37(39)40)35(49)43-32(20-26-12-7-5-8-13-26)36(50)45(4)23-33(47)44(3)22-27-14-9-6-10-15-27/h5-10,12-15,18-19,30-32,46H,11,16-17,20-23,38H2,1-4H3,(H,42,48)(H,43,49)(H4,39,40,41) OHVOJDRKZAWKAU-UHFFFAOYSA-N 50070385 CHEMBL3408736 Mu-type opioid receptor Cavia cutleri 3.1 ChEMBL 10.1016/j.ejmech.2014.12.033 10.7270/Q2M90BCC 25544687 Guillemyn, K; Kleczkowska, P; Lesniak, A; Dyniewicz, J; Van der Poorten, O; Van den Eynde, I; Keresztes, A; Varga, E; Lai, J; Porreca, F; Chung, NN; Lemieux, C; Mika, J; Rojewska, E; Makuch, W; Van Duppen, J; Przewlocka, B; Vanden Broeck, J; Lipkowski, AW; Schiller, PW; Tourwé, D; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070385 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070385&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 118731119 313072401 CHEMBL3408736 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50310058 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H]1Cc2ccccc2CN(CCC(N)=O)C1=O InChI=1S/C30H42N8O5/c1-17-12-21(39)13-18(2)22(17)15-23(31)27(41)36-24(8-5-10-35-30(33)34)28(42)37-25-14-19-6-3-4-7-20(19)16-38(29(25)43)11-9-26(32)40/h3-4,6-7,12-13,23-25,39H,5,8-11,14-16,31H2,1-2H3,(H2,32,40)(H,36,41)(H,37,42)(H4,33,34,35)/t23-,24+,25-/m0/s1 VBTIGXSUDIFYPI-GVAUOCQISA-N 50070386 CHEMBL3408737 Mu-type opioid receptor Cavia cutleri 0.800000 ChEMBL 10.1016/j.ejmech.2014.12.033 10.7270/Q2M90BCC 25544687 Guillemyn, K; Kleczkowska, P; Lesniak, A; Dyniewicz, J; Van der Poorten, O; Van den Eynde, I; Keresztes, A; Varga, E; Lai, J; Porreca, F; Chung, NN; Lemieux, C; Mika, J; Rojewska, E; Makuch, W; Van Duppen, J; Przewlocka, B; Vanden Broeck, J; Lipkowski, AW; Schiller, PW; Tourwé, D; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070386 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070386&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 118731120 313072402 CHEMBL3408737 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50317564 Cc1cc(O)cc(C)c1CC(N)C(=O)N[C@H](CCCN=C(N)N[N+]([O-])=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(O)=O InChI=1S/C40H53N9O10/c1-25-20-29(50)21-26(2)30(25)23-31(41)35(51)45-32(17-11-19-43-39(42)48-49(57)58)36(52)47-34(22-27-12-5-3-6-13-27)37(53)46-33(38(54)55)16-9-10-18-44-40(56)59-24-28-14-7-4-8-15-28/h3-8,12-15,20-21,31-34,50H,9-11,16-19,22-24,41H2,1-2H3,(H,44,56)(H,45,51)(H,46,53)(H,47,52)(H,54,55)(H3,42,43,48)/t31?,32-,33+,34+/m1/s1 DTKHPEUFGZLWTF-OYKWTTPJSA-N 50172013 CHEMBL370701::H-Dmt-D-Arg(NO2)-Phe-Lys(Z)-OH Mu-type opioid receptor Cavia cutleri 63 ChEMBL 10.1021/jm0504959 10.7270/Q2222T9N 16107162 Balboni, G; Cocco, MT; Salvadori, S; Romagnoli, R; Sasaki, Y; Okada, Y; Bryant, SD; Jinsmaa, Y; Lazarus, LH University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172013&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44399025 104058166 CHEMBL370701 C01960 ZINC95612580 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50317566 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(N)=O InChI=1S/C44H52N6O7/c1-28-21-34(51)22-29(2)35(28)25-36(45)43(55)50-26-33-18-10-9-17-32(33)24-39(50)42(54)49-38(23-30-13-5-3-6-14-30)41(53)48-37(40(46)52)19-11-12-20-47-44(56)57-27-31-15-7-4-8-16-31/h3-10,13-18,21-22,36-39,51H,11-12,19-20,23-27,45H2,1-2H3,(H2,46,52)(H,47,56)(H,48,53)(H,49,54)/t36?,37-,38-,39?/m0/s1 PEEGTDLCSQGWIL-FTRCPCMCSA-N 50172017 CHEMBL3143756::{(S)-5-[(S)-2-({2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-3-phenyl-propionylamino]-5-carbamoyl-pentyl}-carbamic acid benzyl ester Mu-type opioid receptor Cavia cutleri 1887 ChEMBL 10.1021/jm0504959 10.7270/Q2222T9N 16107162 Balboni, G; Cocco, MT; Salvadori, S; Romagnoli, R; Sasaki, Y; Okada, Y; Bryant, SD; Jinsmaa, Y; Lazarus, LH University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172017&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11170478 104058170 CHEMBL3143756 ZINC95606660 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50317567 Cc1cc(O)cc(C)c1CC(N)C(=O)N[C@H](CCCN=C(N)N[N+]([O-])=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(N)=O InChI=1S/C40H54N10O9/c1-25-20-29(51)21-26(2)30(25)23-31(41)36(53)47-33(17-11-19-44-39(43)49-50(57)58)37(54)48-34(22-27-12-5-3-6-13-27)38(55)46-32(35(42)52)16-9-10-18-45-40(56)59-24-28-14-7-4-8-15-28/h3-8,12-15,20-21,31-34,51H,9-11,16-19,22-24,41H2,1-2H3,(H2,42,52)(H,45,56)(H,46,55)(H,47,53)(H,48,54)(H3,43,44,49)/t31?,32-,33+,34-/m0/s1 LMMJRHRZYGSRLK-OPTRWXFLSA-N 50172014 CHEMBL371856::H-Dmt-D-Arg(NO2)-Phe-Lys(Z)-NH2 Mu-type opioid receptor Cavia cutleri 0.509000 ChEMBL 10.1021/jm0504959 10.7270/Q2222T9N 16107162 Balboni, G; Cocco, MT; Salvadori, S; Romagnoli, R; Sasaki, Y; Okada, Y; Bryant, SD; Jinsmaa, Y; Lazarus, LH University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172014&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44399141 104058167 CHEMBL371856 ZINC95543124 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50317571 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(O)=O InChI=1S/C44H51N5O8/c1-28-21-34(50)22-29(2)35(28)25-36(45)42(53)49-26-33-18-10-9-17-32(33)24-39(49)41(52)48-38(23-30-13-5-3-6-14-30)40(51)47-37(43(54)55)19-11-12-20-46-44(56)57-27-31-15-7-4-8-16-31/h3-10,13-18,21-22,36-39,50H,11-12,19-20,23-27,45H2,1-2H3,(H,46,56)(H,47,51)(H,48,52)(H,54,55)/t36?,37-,38-,39?/m0/s1 FBNUABHYHZWIRY-FTRCPCMCSA-N 50172015 (S)-2-[(S)-2-({2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-3-phenyl-propionylamino]-6-benzyloxycarbonylamino-hexanoic acid::CHEMBL3143757 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm0504959 10.7270/Q2222T9N 16107162 Balboni, G; Cocco, MT; Salvadori, S; Romagnoli, R; Sasaki, Y; Okada, Y; Bryant, SD; Jinsmaa, Y; Lazarus, LH University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172015&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11411713 104058168 CHEMBL3143757 ZINC95612398 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50321975 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCCCCNC(=O)C1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C InChI=1S/C38H51N5O5/c1-23-15-29(44)16-24(2)31(23)20-33(39)36(46)41-13-9-5-6-10-14-42-37(47)35-19-27-11-7-8-12-28(27)22-43(35)38(48)34(40)21-32-25(3)17-30(45)18-26(32)4/h7-8,11-12,15-18,33-35,44-45H,5-6,9-10,13-14,19-22,39-40H2,1-4H3,(H,41,46)(H,42,47)/t33-,34-,35?/m0/s1 PKRAENCMWFWKSB-IEKJTBOOSA-N 50174198 CHEMBL372130::H-Dmt-Tic-NH-(CH2)6-NH-Dmt-H Mu-type opioid receptor Cavia cutleri 5900 ChEMBL 10.1016/j.bmcl.2005.08.073 10.7270/Q2MK6CFQ 16183273 Li, T; Shiotani, K; Miyazaki, A; Fujita, Y; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50174198 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50174198&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44405653 104060020 CHEMBL372130 ZINC28530042 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50321977 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)NCCCCCCNC(=O)[C@@H](N)Cc1ccccc1 InChI=1S/C36H47N5O4/c1-24-18-29(42)19-25(2)30(24)22-32(38)36(45)41-23-28-15-9-8-14-27(28)21-33(41)35(44)40-17-11-4-3-10-16-39-34(43)31(37)20-26-12-6-5-7-13-26/h5-9,12-15,18-19,31-33,42H,3-4,10-11,16-17,20-23,37-38H2,1-2H3,(H,39,43)(H,40,44)/t31-,32-,33?/m0/s1 VWEMLWZEBKVSHE-KOPQTXDBSA-N 50174199 CHEMBL198909::H-Dmt-Tic-NH-(CH2)6-NH-Phe-H Mu-type opioid receptor Cavia cutleri 5550 ChEMBL 10.1016/j.bmcl.2005.08.073 10.7270/Q2MK6CFQ 16183273 Li, T; Shiotani, K; Miyazaki, A; Fujita, Y; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50174199 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50174199&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44405656 104060021 CHEMBL198909 ZINC28530071 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50321980 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)NCCCCCCNC(=O)C1Cc2ccccc2CN1 InChI=1S/C37H47N5O4/c1-24-17-30(43)18-25(2)31(24)21-32(38)37(46)42-23-29-14-8-6-12-27(29)20-34(42)36(45)40-16-10-4-3-9-15-39-35(44)33-19-26-11-5-7-13-28(26)22-41-33/h5-8,11-14,17-18,32-34,41,43H,3-4,9-10,15-16,19-23,38H2,1-2H3,(H,39,44)(H,40,45)/t32-,33?,34?/m0/s1 SIUMEPYYYNRSSX-BGVJURHFSA-N 50174200 CHEMBL380590::H-Dmt-Tic-NH-(CH2)6-NH-Tic-H Mu-type opioid receptor Cavia cutleri 1600 ChEMBL 10.1016/j.bmcl.2005.08.073 10.7270/Q2MK6CFQ 16183273 Li, T; Shiotani, K; Miyazaki, A; Fujita, Y; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50174200 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50174200&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44405654 104060022 CHEMBL380590 ZINC28530055 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50327155 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C46H56N10O10/c1-27(51-43(63)35(47)21-31-13-17-33(57)18-14-31)41(61)49-25-39(59)53-37(23-29-9-5-3-6-10-29)45(65)55-56-46(66)38(24-30-11-7-4-8-12-30)54-40(60)26-50-42(62)28(2)52-44(64)36(48)22-32-15-19-34(58)20-16-32/h3-20,27-28,35-38,57-58H,21-26,47-48H2,1-2H3,(H,49,61)(H,50,62)(H,51,63)(H,52,64)(H,53,59)(H,54,60)(H,55,65)(H,56,66)/t27-,28-,35+,36+,37+,38+/m1/s1 DESSEGDLRYOPTJ-VRANXALZSA-N 21014 (2S)-2-amino-N-[(1R)-1-[({[(1S)-1-{N'-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanoyl]hydrazinecarbonyl}-2-phenylethyl]carbamoyl}methyl)carbamoyl]ethyl]-3-(4-hydroxyphenyl)propanamide::(Tyr-Ala-Gly-Phe-NH2)2::Biphalin::CHEMBL200199::bis(Tyr-Ala-Gly-PheNH2)hydrazide::enkephalin dimer Mu-type opioid receptor Cavia cutleri 8.8 ChEMBL 10.1016/j.bmcl.2005.09.080 10.7270/Q24X57BF 16275086 Mollica, A; Davis, P; Ma, SW; Porreca, F; Lai, J; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21014&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5487663 49689087 CHEMBL200199 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50327160 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@@H](Cc2ccccc2)C(=O)NNC(=O)[C@H](Cc2ccccc2)NC(=O)CNC1=O InChI=1S/C46H54N10O10S2/c47-33(19-29-11-15-31(57)16-12-29)41(61)53-37-25-67-68-26-38(54-42(62)34(48)20-30-13-17-32(58)18-14-30)44(64)50-24-40(60)52-36(22-28-9-5-2-6-10-28)46(66)56-55-45(65)35(21-27-7-3-1-4-8-27)51-39(59)23-49-43(37)63/h1-18,33-38,57-58H,19-26,47-48H2,(H,49,63)(H,50,64)(H,51,59)(H,52,60)(H,53,61)(H,54,62)(H,55,65)(H,56,66)/t33-,34-,35-,36-,37+,38+/m0/s1 IVZGEIYAIJCDDR-AEKIIXOMSA-N 50176702 (S)-2-amino-N-{(4S,10S,15S,21S)-21-[(S)-2-amino-3-(4-hydroxy-phenyl)-propionylamino]-10,15-dibenzyl-5,8,11,14,17,20-hexaoxo-1,2-dithia-6,9,12,13,16,19-hexaaza-cyclodocos-4-yl}-3-(4-hydroxy-phenyl)-propionamide::CHEMBL200129 Mu-type opioid receptor Cavia cutleri 25 ChEMBL 10.1016/j.bmcl.2005.09.080 10.7270/Q24X57BF 16275086 Mollica, A; Davis, P; Ma, SW; Porreca, F; Lai, J; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50176702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50176702&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44406568 104062349 CHEMBL200129 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50327162 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@@H](Cc2ccccc2)C(=O)NNC(=O)[C@H](Cc2ccccc2)NC(=O)CNC1=O InChI=1S/C46H54N10O10S2/c47-33(19-29-11-15-31(57)16-12-29)41(61)53-37-25-67-68-26-38(54-42(62)34(48)20-30-13-17-32(58)18-14-30)44(64)50-24-40(60)52-36(22-28-9-5-2-6-10-28)46(66)56-55-45(65)35(21-27-7-3-1-4-8-27)51-39(59)23-49-43(37)63/h1-18,33-38,57-58H,19-26,47-48H2,(H,49,63)(H,50,64)(H,51,59)(H,52,60)(H,53,61)(H,54,62)(H,55,65)(H,56,66)/t33-,34-,35-,36-,37-,38-/m0/s1 IVZGEIYAIJCDDR-JPRYDEJLSA-N 50176703 (S)-2-Amino-N-{(4R,10S,15S,21R)-21-[(S)-2-amino-3-(4-hydroxy-phenyl)-propionylamino]-10,15-dibenzyl-5,8,11,14,17,20-hexaoxo-1,2-dithia-6,9,12,13,16,19-hexaaza-cyclodocos-4-yl}-3-(4-hydroxy-phenyl)-propionamide::CHEMBL372787 Mu-type opioid receptor Cavia cutleri 420 ChEMBL 10.1016/j.bmcl.2005.09.080 10.7270/Q24X57BF 16275086 Mollica, A; Davis, P; Ma, SW; Porreca, F; Lai, J; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50176703 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50176703&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44406605 104062350 CHEMBL372787 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50317560 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C32H49N9O5/c1-19-15-22(42)16-20(2)23(19)18-24(34)29(44)40-26(12-8-14-38-32(36)37)30(45)41-27(17-21-9-4-3-5-10-21)31(46)39-25(28(35)43)11-6-7-13-33/h3-5,9-10,15-16,24-27,42H,6-8,11-14,17-18,33-34H2,1-2H3,(H2,35,43)(H,39,46)(H,40,44)(H,41,45)(H4,36,37,38)/t24-,25-,26+,27-/m0/s1 FIAKHZXVLBNZLW-NFGXINMFSA-N 50010483 CHEMBL2181202 Mu-type opioid receptor Cavia cutleri 1.4 ChEMBL 10.1021/jm0504959 10.7270/Q2222T9N 16107162 Balboni, G; Cocco, MT; Salvadori, S; Romagnoli, R; Sasaki, Y; Okada, Y; Bryant, SD; Jinsmaa, Y; Lazarus, LH University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010483&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9809562 242057631 CHEMBL2181202 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50331763 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCc1nc2ccccc2n1CC(N)=O InChI=1S/C31H34N6O4/c1-18-11-22(38)12-19(2)23(18)14-24(32)31(41)37-16-21-8-4-3-7-20(21)13-27(37)30(40)34-15-29-35-25-9-5-6-10-26(25)36(29)17-28(33)39/h3-12,24,27,38H,13-17,32H2,1-2H3,(H2,33,39)(H,34,40)/t24-,27-/m0/s1 OUJSALASYUKUMI-IGKIAQTJSA-N 50179188 (S)-N-((1-(2-amino-2-oxoethyl)-1H-benzo[d]imidazol-2-yl)methyl)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::CHEMBL322300 Mu-type opioid receptor Cavia cutleri 77 ChEMBL 10.1021/jm058259l 10.7270/Q24J0DQR 16366592 Balboni, G; Guerrini, R; Salvadori, S; Negri, L; Giannini, E; Bryant, SD; Jinsmaa, Y; Lazarus, LH University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179188 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179188&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11526885 104064416 CHEMBL322300 ZINC26840083 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50331765 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCc1nc2ccccc2n1CC(O)=O InChI=1S/C31H33N5O5/c1-18-11-22(37)12-19(2)23(18)14-24(32)31(41)36-16-21-8-4-3-7-20(21)13-27(36)30(40)33-15-28-34-25-9-5-6-10-26(25)35(28)17-29(38)39/h3-12,24,27,37H,13-17,32H2,1-2H3,(H,33,40)(H,38,39)/t24-,27-/m0/s1 RVMCEJFTWDWACY-IGKIAQTJSA-N 50179190 2-(2-(((S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido)methyl)-1H-benzo[d]imidazol-1-yl)acetic acid::CHEMBL354966 Mu-type opioid receptor Cavia cutleri 3193 ChEMBL 10.1021/jm058259l 10.7270/Q24J0DQR 16366592 Balboni, G; Guerrini, R; Salvadori, S; Negri, L; Giannini, E; Bryant, SD; Jinsmaa, Y; Lazarus, LH University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179190&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10940664 104064418 CHEMBL354966 ZINC27985080 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50331766 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCc1nc2ccccc2n1CC=C InChI=1S/C32H35N5O3/c1-4-13-36-28-12-8-7-11-27(28)35-30(36)18-34-31(39)29-16-22-9-5-6-10-23(22)19-37(29)32(40)26(33)17-25-20(2)14-24(38)15-21(25)3/h4-12,14-15,26,29,38H,1,13,16-19,33H2,2-3H3,(H,34,39)/t26-,29-/m0/s1 UZQBGPGDTHZZAU-WNJJXGMVSA-N 50179189 (S)-N-((1-allyl-1H-benzo[d]imidazol-2-yl)methyl)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::CHEMBL354392 Mu-type opioid receptor Cavia cutleri 72 ChEMBL 10.1021/jm058259l 10.7270/Q24J0DQR 16366592 Balboni, G; Guerrini, R; Salvadori, S; Negri, L; Giannini, E; Bryant, SD; Jinsmaa, Y; Lazarus, LH University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179189 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179189&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11642336 104064417 CHEMBL354392 ZINC28003772 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50331770 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCc1nc2ccccc2n1C InChI=1S/C30H33N5O3/c1-18-12-22(36)13-19(2)23(18)15-24(31)30(38)35-17-21-9-5-4-8-20(21)14-27(35)29(37)32-16-28-33-25-10-6-7-11-26(25)34(28)3/h4-13,24,27,36H,14-17,31H2,1-3H3,(H,32,37)/t24-,27-/m0/s1 SMTPLKRKLRVDQP-IGKIAQTJSA-N 50179192 (S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-N-((1-methyl-1H-benzo[d]imidazol-2-yl)methyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::CHEMBL422547 Mu-type opioid receptor Cavia cutleri 450 ChEMBL 10.1021/jm058259l 10.7270/Q24J0DQR 16366592 Balboni, G; Guerrini, R; Salvadori, S; Negri, L; Giannini, E; Bryant, SD; Jinsmaa, Y; Lazarus, LH University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179192 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179192&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11548007 104064420 CHEMBL422547 ZINC13677761 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50331774 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCc1nc2ccccc2n1Cc1ccccc1 InChI=1S/C36H37N5O3/c1-23-16-28(42)17-24(2)29(23)19-30(37)36(44)41-22-27-13-7-6-12-26(27)18-33(41)35(43)38-20-34-39-31-14-8-9-15-32(31)40(34)21-25-10-4-3-5-11-25/h3-17,30,33,42H,18-22,37H2,1-2H3,(H,38,43)/t30-,33-/m0/s1 BJHRGIVVJRVBQV-DITALETJSA-N 50179186 (S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-N-((1-benzyl-1H-benzo[d]imidazol-2-yl)methyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::CHEMBL436063 Mu-type opioid receptor Cavia cutleri 245 ChEMBL 10.1021/jm058259l 10.7270/Q24J0DQR 16366592 Balboni, G; Guerrini, R; Salvadori, S; Negri, L; Giannini, E; Bryant, SD; Jinsmaa, Y; Lazarus, LH University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179186 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179186&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11650029 104064414 CHEMBL436063 ZINC27982172 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50331777 CCOC(=O)Cn1c(CNC(=O)[C@@H]2Cc3ccccc3CN2C(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)nc2ccccc12 InChI=1S/C33H37N5O5/c1-4-43-31(40)19-37-28-12-8-7-11-27(28)36-30(37)17-35-32(41)29-15-22-9-5-6-10-23(22)18-38(29)33(42)26(34)16-25-20(2)13-24(39)14-21(25)3/h5-14,26,29,39H,4,15-19,34H2,1-3H3,(H,35,41)/t26-,29-/m0/s1 PZVVDRYHHWKNGZ-WNJJXGMVSA-N 50179187 CHEMBL197183::ethyl 2-(2-(((S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido)methyl)-1H-benzo[d]imidazol-1-yl)acetate Mu-type opioid receptor Cavia cutleri 30 ChEMBL 10.1021/jm058259l 10.7270/Q24J0DQR 16366592 Balboni, G; Guerrini, R; Salvadori, S; Negri, L; Giannini, E; Bryant, SD; Jinsmaa, Y; Lazarus, LH University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179187 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179187&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11125686 104064415 CHEMBL197183 ZINC28530369 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50331780 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C37H52N8O10/c1-19(2)30(36(54)40-18-28(39)47)45-37(55)31(20(3)4)44-35(53)27(17-29(48)49)43-34(52)26(16-22-9-7-6-8-10-22)42-32(50)21(5)41-33(51)25(38)15-23-11-13-24(46)14-12-23/h6-14,19-21,25-27,30-31,46H,15-18,38H2,1-5H3,(H2,39,47)(H,40,54)(H,41,51)(H,42,50)(H,43,52)(H,44,53)(H,45,55)(H,48,49)/t21-,25+,26+,27+,30+,31+/m1/s1 CJAORFIPPWIGPG-QXYJMILXSA-N 50001468 (S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::3-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL317956::H-Tyr-D-Ala-Phe-Asp-Val-Val-Gly-NH2::deltorphin C Mu-type opioid receptor Cavia cutleri 1300 ChEMBL 10.1021/jm058259l 10.7270/Q24J0DQR 16366592 Balboni, G; Guerrini, R; Salvadori, S; Negri, L; Giannini, E; Bryant, SD; Jinsmaa, Y; Lazarus, LH University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001468&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10055958 103915933 CHEMBL317956 C18097 ZINC95610551 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50331782 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O InChI=1S/C40H50N8O10/c1-23(44-37(55)29(41)18-25-9-13-27(50)14-10-25)36(54)46-30(19-24-6-3-2-4-7-24)38(56)43-21-34(52)45-31(20-26-11-15-28(51)16-12-26)40(58)48-17-5-8-33(48)39(57)47-32(22-49)35(42)53/h2-4,6-7,9-16,23,29-33,49-51H,5,8,17-22,41H2,1H3,(H2,42,53)(H,43,56)(H,44,55)(H,45,52)(H,46,54)(H,47,57)/t23-,29+,30+,31+,32+,33+/m1/s1 FHZPGIUBXYVUOY-VWGYHWLBSA-N 50059841 (S)-1-[(S)-2-[2-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid ((S)-1-carbamoyl-2-hydroxy-ethyl)-amide::(S)-2-Amino-N-{(R)-1-[(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethylcarbamoyl]-ethyl}-3-(4-hydroxy-phenyl)-propionamide::1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide::1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide (Dermorphin)::1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide(Dermorphin)::CHEMBL278789::DERMORPHIN::Dermorphin;1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide::H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2::Tyr-Ala-Phe-Gly-Tyr-Pro-Ser::YAFGYPS-NH2 Mu-type opioid receptor Cavia cutleri 1.9 ChEMBL 10.1021/jm058259l 10.7270/Q24J0DQR 16366592 Balboni, G; Guerrini, R; Salvadori, S; Negri, L; Giannini, E; Bryant, SD; Jinsmaa, Y; Lazarus, LH University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059841 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059841&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5485199 103955620 CHEMBL278789 ZINC95548678 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50331785 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCc1nc2ccccc2[nH]1 InChI=1S/C29H31N5O3/c1-17-11-21(35)12-18(2)22(17)14-23(30)29(37)34-16-20-8-4-3-7-19(20)13-26(34)28(36)31-15-27-32-24-9-5-6-10-25(24)33-27/h3-12,23,26,35H,13-16,30H2,1-2H3,(H,31,36)(H,32,33)/t23-,26-/m0/s1 XRZTZWCPHAJWJQ-OZXSUGGESA-N 50179191 (S)-N-((1H-benzo[d]imidazol-2-yl)methyl)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid (1H-benzoimidazol-2-ylmethyl)-amide::CHEMBL109390::H-Dmt-Tic-NH-CH2-Bid::UFP-502 Mu-type opioid receptor Cavia cutleri 40.7 ChEMBL 10.1021/jm058259l 10.7270/Q24J0DQR 16366592 Balboni, G; Guerrini, R; Salvadori, S; Negri, L; Giannini, E; Bryant, SD; Jinsmaa, Y; Lazarus, LH University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179191&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10345770 104064419 CHEMBL109390 ZINC13472298 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50331790 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCc1nc2ccccc2n1CC1CC1 InChI=1S/C33H37N5O3/c1-20-13-25(39)14-21(2)26(20)16-27(34)33(41)38-19-24-8-4-3-7-23(24)15-30(38)32(40)35-17-31-36-28-9-5-6-10-29(28)37(31)18-22-11-12-22/h3-10,13-14,22,27,30,39H,11-12,15-19,34H2,1-2H3,(H,35,40)/t27-,30-/m0/s1 YDJKLKDDLXZINK-FIBWVYCGSA-N 50179193 (S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-N-((1-(cyclopropylmethyl)-1H-benzo[d]imidazol-2-yl)methyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::CHEMBL173884 Mu-type opioid receptor Cavia cutleri 64 ChEMBL 10.1021/jm058259l 10.7270/Q24J0DQR 16366592 Balboni, G; Guerrini, R; Salvadori, S; Negri, L; Giannini, E; Bryant, SD; Jinsmaa, Y; Lazarus, LH University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179193 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179193&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11584813 104064421 CHEMBL173884 ZINC28096699 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50330890 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)NCc1[nH]c(=O)c(CNC(=O)C2Cc3ccccc3CN2C(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)nc1C InChI=1S/C49H56N8O7/c1-26-14-35(58)15-27(2)37(26)20-39(50)48(63)56-24-33-12-8-6-10-31(33)18-43(56)46(61)52-22-41-30(5)54-42(45(60)55-41)23-53-47(62)44-19-32-11-7-9-13-34(32)25-57(44)49(64)40(51)21-38-28(3)16-36(59)17-29(38)4/h6-17,39-40,43-44,58-59H,18-25,50-51H2,1-5H3,(H,52,61)(H,53,62)(H,55,60)/t39-,40-,43?,44?/m0/s1 BOYVBTQTUISOKQ-XQIDWOBFSA-N 50178755 3,6-bis(Dmt-Tic-NH-methyl)-2(1H)-pyrazinone::CHEMBL200890 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm050377l 10.7270/Q2C53KD9 16335927 Li, T; Fujita, Y; Shiotani, K; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Salvadori, S; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50178755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50178755&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44405233 104064028 CHEMBL200890 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50330896 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)NCCc1[nH]c(=O)c(CCNC(=O)C2Cc3ccccc3CN2C(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)nc1C InChI=1S/C51H60N8O7/c1-28-18-37(60)19-29(2)39(28)24-41(52)50(65)58-26-35-12-8-6-10-33(35)22-45(58)48(63)54-16-14-43-32(5)56-44(47(62)57-43)15-17-55-49(64)46-23-34-11-7-9-13-36(34)27-59(46)51(66)42(53)25-40-30(3)20-38(61)21-31(40)4/h6-13,18-21,41-42,45-46,60-61H,14-17,22-27,52-53H2,1-5H3,(H,54,63)(H,55,64)(H,57,62)/t41-,42-,45?,46?/m0/s1 OOTASVYBVWGNJP-KJLUANBESA-N 50178761 3,6-bis(Dmt-Tic-NH-ethyl)-2(1H)-pyrazinone::CHEMBL198800 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm050377l 10.7270/Q2C53KD9 16335927 Li, T; Fujita, Y; Shiotani, K; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Salvadori, S; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50178761 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50178761&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44405192 104064034 CHEMBL198800 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50330897 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)NCCCc1[nH]c(=O)c(CCCNC(=O)C2Cc3ccccc3CN2C(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)nc1C InChI=1S/C53H64N8O7/c1-30-20-39(62)21-31(2)41(30)26-43(54)52(67)60-28-37-14-8-6-12-35(37)24-47(60)50(65)56-18-10-16-45-34(5)58-46(49(64)59-45)17-11-19-57-51(66)48-25-36-13-7-9-15-38(36)29-61(48)53(68)44(55)27-42-32(3)22-40(63)23-33(42)4/h6-9,12-15,20-23,43-44,47-48,62-63H,10-11,16-19,24-29,54-55H2,1-5H3,(H,56,65)(H,57,66)(H,59,64)/t43-,44-,47?,48?/m0/s1 NATWHSVYZBCLOS-OYVXWBFTSA-N 50178763 3,6-bis(Dmt-Tic-NH-propyl)-2(1H)-pyrazinone::CHEMBL381874 Mu-type opioid receptor Cavia cutleri 7025 ChEMBL 10.1021/jm050377l 10.7270/Q2C53KD9 16335927 Li, T; Fujita, Y; Shiotani, K; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Salvadori, S; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50178763 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50178763&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44405208 104064036 CHEMBL381874 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50330898 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)NCCCCc1nc(C)c(CCCNC(=O)C2Cc3ccccc3CN2C(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)[nH]c1=O InChI=1S/C54H66N8O7/c1-31-21-40(63)22-32(2)42(31)27-44(55)53(68)61-29-38-15-8-6-13-36(38)25-48(61)51(66)57-19-11-10-17-47-50(65)60-46(35(5)59-47)18-12-20-58-52(67)49-26-37-14-7-9-16-39(37)30-62(49)54(69)45(56)28-43-33(3)23-41(64)24-34(43)4/h6-9,13-16,21-24,44-45,48-49,63-64H,10-12,17-20,25-30,55-56H2,1-5H3,(H,57,66)(H,58,67)(H,60,65)/t44-,45-,48?,49?/m0/s1 CHKFIUAMEUVMNR-FHRQCFKPSA-N 50178757 3-(Dmt-Tic-NH-butyl)-6-(Dmt-Tic-NH-propyl)-2-(1H)-pyrazinone::CHEMBL370398 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm050377l 10.7270/Q2C53KD9 16335927 Li, T; Fujita, Y; Shiotani, K; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Salvadori, S; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50178757 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50178757&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44405152 104064030 CHEMBL370398 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50330902 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)NCCCCc1[nH]c(=O)c(CCNC(=O)C2Cc3ccccc3CN2C(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)nc1C InChI=1S/C53H64N8O7/c1-30-20-39(62)21-31(2)41(30)26-43(54)52(67)60-28-37-14-8-6-12-35(37)24-47(60)50(65)56-18-11-10-16-45-34(5)58-46(49(64)59-45)17-19-57-51(66)48-25-36-13-7-9-15-38(36)29-61(48)53(68)44(55)27-42-32(3)22-40(63)23-33(42)4/h6-9,12-15,20-23,43-44,47-48,62-63H,10-11,16-19,24-29,54-55H2,1-5H3,(H,56,65)(H,57,66)(H,59,64)/t43-,44-,47?,48?/m0/s1 QSLVDGURDXVNRV-OYVXWBFTSA-N 50178756 3-(Dmt-Tic-NH-ethyl)-6-(Dmt-Tic-NH-butyl)-2-(1H)-pyrazinone::CHEMBL196774 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm050377l 10.7270/Q2C53KD9 16335927 Li, T; Fujita, Y; Shiotani, K; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Salvadori, S; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50178756 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50178756&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44405155 104064029 CHEMBL196774 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50330904 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)NCCCCCCNC(=O)C1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C InChI=1S/C48H60N6O6/c1-29-19-37(55)20-30(2)39(29)25-41(49)47(59)53-27-35-15-9-7-13-33(35)23-43(53)45(57)51-17-11-5-6-12-18-52-46(58)44-24-34-14-8-10-16-36(34)28-54(44)48(60)42(50)26-40-31(3)21-38(56)22-32(40)4/h7-10,13-16,19-22,41-44,55-56H,5-6,11-12,17-18,23-28,49-50H2,1-4H3,(H,51,57)(H,52,58)/t41-,42-,43?,44?/m0/s1 VJIXEMXKNBJTQB-GCGBLBKRSA-N 50178762 1,6-bis-(Dmt-Tic-amino)hexane::CHEMBL197185 Mu-type opioid receptor Cavia cutleri 2715 ChEMBL 10.1021/jm050377l 10.7270/Q2C53KD9 16335927 Li, T; Fujita, Y; Shiotani, K; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Salvadori, S; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50178762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50178762&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44405159 104064035 CHEMBL197185 ZINC95606766 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50330908 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)NCCCCc1[nH]c(=O)c(CCCNC(=O)C2Cc3ccccc3CN2C(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)nc1C InChI=1S/C54H66N8O7/c1-31-21-40(63)22-32(2)42(31)27-44(55)53(68)61-29-38-15-8-6-13-36(38)25-48(61)51(66)57-19-11-10-17-46-35(5)59-47(50(65)60-46)18-12-20-58-52(67)49-26-37-14-7-9-16-39(37)30-62(49)54(69)45(56)28-43-33(3)23-41(64)24-34(43)4/h6-9,13-16,21-24,44-45,48-49,63-64H,10-12,17-20,25-30,55-56H2,1-5H3,(H,57,66)(H,58,67)(H,60,65)/t44-,45-,48?,49?/m0/s1 KHLLDLLKRUGXCV-FHRQCFKPSA-N 50178764 3-(Dmt-Tic-NH-propyl)-6-(Dmt-Tic-NH-butyl)-2-(1H)-pyrazinone::CHEMBL198646 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm050377l 10.7270/Q2C53KD9 16335927 Li, T; Fujita, Y; Shiotani, K; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Salvadori, S; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50178764 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50178764&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44405151 104064037 CHEMBL198646 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50330909 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)NCCCCNC(=O)C1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C InChI=1S/C46H56N6O6/c1-27-17-35(53)18-28(2)37(27)23-39(47)45(57)51-25-33-13-7-5-11-31(33)21-41(51)43(55)49-15-9-10-16-50-44(56)42-22-32-12-6-8-14-34(32)26-52(42)46(58)40(48)24-38-29(3)19-36(54)20-30(38)4/h5-8,11-14,17-20,39-42,53-54H,9-10,15-16,21-26,47-48H2,1-4H3,(H,49,55)(H,50,56)/t39-,40-,41?,42?/m0/s1 JSRJJBASKHLXAZ-YZNAZWRISA-N 50178765 1,4-bis-(Dmt-Tic-amino)butane::CHEMBL370197 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm050377l 10.7270/Q2C53KD9 16335927 Li, T; Fujita, Y; Shiotani, K; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Salvadori, S; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50178765 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50178765&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44405158 104064038 CHEMBL370197 ZINC95543138 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50330916 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)NCCCCCCCCCCNC(=O)C1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C InChI=1S/C52H68N6O6/c1-33-23-41(59)24-34(2)43(33)29-45(53)51(63)57-31-39-19-13-11-17-37(39)27-47(57)49(61)55-21-15-9-7-5-6-8-10-16-22-56-50(62)48-28-38-18-12-14-20-40(38)32-58(48)52(64)46(54)30-44-35(3)25-42(60)26-36(44)4/h11-14,17-20,23-26,45-48,59-60H,5-10,15-16,21-22,27-32,53-54H2,1-4H3,(H,55,61)(H,56,62)/t45-,46-,47?,48?/m0/s1 WGSCXEFFOVZNEM-QCSGVJIWSA-N 50178760 1,10-bis-(Dmt-Tic-amino)decane::CHEMBL373192 Mu-type opioid receptor Cavia cutleri 5425 ChEMBL 10.1021/jm050377l 10.7270/Q2C53KD9 16335927 Li, T; Fujita, Y; Shiotani, K; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Salvadori, S; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50178760 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50178760&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44405160 104064033 CHEMBL373192 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50330917 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)NCCCCc1[nH]c(=O)c(CCCCNC(=O)C2Cc3ccccc3CN2C(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)nc1C InChI=1S/C55H68N8O7/c1-32-22-41(64)23-33(2)43(32)28-45(56)54(69)62-30-39-16-8-6-14-37(39)26-49(62)52(67)58-20-12-10-18-47-36(5)60-48(51(66)61-47)19-11-13-21-59-53(68)50-27-38-15-7-9-17-40(38)31-63(50)55(70)46(57)29-44-34(3)24-42(65)25-35(44)4/h6-9,14-17,22-25,45-46,49-50,64-65H,10-13,18-21,26-31,56-57H2,1-5H3,(H,58,67)(H,59,68)(H,61,66)/t45-,46-,49?,50?/m0/s1 HHTSJHJHPFGARW-RFLUKDKXSA-N 50178758 3,6-bis(Dmt-Tic-NH-butyl)-2(1H)-pyrazinone::CHEMBL373668 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm050377l 10.7270/Q2C53KD9 16335927 Li, T; Fujita, Y; Shiotani, K; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Salvadori, S; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50178758 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50178758&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44405182 104064031 CHEMBL373668 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50330924 CN(C)[C@@H](Cc1c(C)cc(O)cc1C)C(=O)N1Cc2ccccc2CC1C(=O)NCCCc1[nH]c(=O)c(CCCNC(=O)C2Cc3ccccc3CN2C(=O)[C@H](Cc2c(C)cc(O)cc2C)N(C)C)nc1C InChI=1S/C57H72N8O7/c1-34-24-43(66)25-35(2)45(34)30-51(62(6)7)56(71)64-32-41-18-12-10-16-39(41)28-49(64)54(69)58-22-14-20-47-38(5)60-48(53(68)61-47)21-15-23-59-55(70)50-29-40-17-11-13-19-42(40)33-65(50)57(72)52(63(8)9)31-46-36(3)26-44(67)27-37(46)4/h10-13,16-19,24-27,49-52,66-67H,14-15,20-23,28-33H2,1-9H3,(H,58,69)(H,59,70)(H,61,68)/t49?,50?,51-,52-/m0/s1 GDJAYRWKBABTAT-VRNAFJHGSA-N 50178754 3,6-bis-(N,N-dimethyl-Dmt-Tic-NH-propyl)-2(1H)-pyrazinone::CHEMBL261905 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm050377l 10.7270/Q2C53KD9 16335927 Li, T; Fujita, Y; Shiotani, K; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Salvadori, S; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50178754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50178754&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44405154 104064027 CHEMBL261905 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50330926 CN(C)[C@@H](Cc1c(C)cc(O)cc1C)C(=O)N1Cc2ccccc2CC1C(=O)NCCCCCCNC(=O)C1Cc2ccccc2CN1C(=O)[C@H](Cc1c(C)cc(O)cc1C)N(C)C InChI=1S/C52H68N6O6/c1-33-23-41(59)24-34(2)43(33)29-47(55(5)6)51(63)57-31-39-19-13-11-17-37(39)27-45(57)49(61)53-21-15-9-10-16-22-54-50(62)46-28-38-18-12-14-20-40(38)32-58(46)52(64)48(56(7)8)30-44-35(3)25-42(60)26-36(44)4/h11-14,17-20,23-26,45-48,59-60H,9-10,15-16,21-22,27-32H2,1-8H3,(H,53,61)(H,54,62)/t45?,46?,47-,48-/m0/s1 WQLMNYRHCQXDKA-QYXCYUBVSA-N 50178759 1,6-bis-(N,N-dimethyl-Dmt-Tic-NH)hexane::CHEMBL370399 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm050377l 10.7270/Q2C53KD9 16335927 Li, T; Fujita, Y; Shiotani, K; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Salvadori, S; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50178759 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50178759&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44405153 104064032 CHEMBL370399 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50338754 N[C@@H](Cc1ccc(cc1)C(N)=O)C(=O)N1CCCC[C@H]1c1nc(c[nH]1)-c1ccccc1 InChI=1S/C24H27N5O2/c25-19(14-16-9-11-18(12-10-16)22(26)30)24(31)29-13-5-4-8-21(29)23-27-15-20(28-23)17-6-2-1-3-7-17/h1-3,6-7,9-12,15,19,21H,4-5,8,13-14,25H2,(H2,26,30)(H,27,28)/t19-,21-/m0/s1 YALMCURVZITNRZ-FPOVZHCZSA-N 50182944 4-((S)-2-amino-3-oxo-3-((S)-2-(4-phenyl-1H-imidazol-2-yl)piperidin-1-yl)propyl)benzamide::CHEMBL204996 Mu-type opioid receptor Cavia cutleri 100 ChEMBL 10.1016/j.bmcl.2006.01.082 10.7270/Q29G5MDZ 16483774 Breslin, HJ; Cai, C; Miskowski, TA; Coutinho, SV; Zhang, SP; Hornby, P; He, W Johnson & Johnson Pharmaceutical Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50182944 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50182944&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11742693 104067559 CHEMBL204996 ZINC36216185 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50338764 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCCC[C@H]1c1nc(c[nH]1)-c1ccccc1 InChI=1S/C25H30N4O2/c1-16-12-19(30)13-17(2)20(16)14-21(26)25(31)29-11-7-6-10-23(29)24-27-15-22(28-24)18-8-4-3-5-9-18/h3-5,8-9,12-13,15,21,23,30H,6-7,10-11,14,26H2,1-2H3,(H,27,28)/t21-,23-/m0/s1 KLOMLLAPAMKOJE-GMAHTHKFSA-N 50182939 (S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-((S)-2-(4-phenyl-1H-imidazol-2-yl)piperidin-1-yl)propan-1-one::CHEMBL377069 Mu-type opioid receptor Cavia cutleri 2 ChEMBL 10.1016/j.bmcl.2006.01.082 10.7270/Q29G5MDZ 16483774 Breslin, HJ; Cai, C; Miskowski, TA; Coutinho, SV; Zhang, SP; Hornby, P; He, W Johnson & Johnson Pharmaceutical Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50182939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50182939&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9909946 104067554 CHEMBL377069 ZINC34024642 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50338766 Cc1cc(cc(C)c1C[C@H](N)C(=O)N1CCCC[C@H]1c1nc(c[nH]1)-c1ccccc1)C(N)=O InChI=1S/C26H31N5O2/c1-16-12-19(24(28)32)13-17(2)20(16)14-21(27)26(33)31-11-7-6-10-23(31)25-29-15-22(30-25)18-8-4-3-5-9-18/h3-5,8-9,12-13,15,21,23H,6-7,10-11,14,27H2,1-2H3,(H2,28,32)(H,29,30)/t21-,23-/m0/s1 ORFHSHFAWAJFLG-GMAHTHKFSA-N 50182946 4-((S)-2-amino-3-oxo-3-((S)-2-(4-phenyl-1H-imidazol-2-yl)piperidin-1-yl)propyl)-3,5-dimethylbenzamide::CHEMBL205049 Mu-type opioid receptor Cavia cutleri 9 ChEMBL 10.1016/j.bmcl.2006.01.082 10.7270/Q29G5MDZ 16483774 Breslin, HJ; Cai, C; Miskowski, TA; Coutinho, SV; Zhang, SP; Hornby, P; He, W Johnson & Johnson Pharmaceutical Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50182946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50182946&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10343492 104067561 CHEMBL205049 ZINC36216196 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50338777 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1c1nc(c[nH]1)-c1ccccc1 InChI=1S/C29H30N4O2/c1-18-12-23(34)13-19(2)24(18)15-25(30)29(35)33-17-22-11-7-6-10-21(22)14-27(33)28-31-16-26(32-28)20-8-4-3-5-9-20/h3-13,16,25,27,34H,14-15,17,30H2,1-2H3,(H,31,32)/t25-,27-/m0/s1 WIEPDHSIJOOHOZ-BDYUSTAISA-N 50182942 (S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-((S)-3-(4-phenyl-1H-imidazol-2-yl)-3,4-dihydroisoquinolin-2(1H)-yl)propan-1-one::CHEMBL208454 Mu-type opioid receptor Cavia cutleri 27 ChEMBL 10.1016/j.bmcl.2006.01.082 10.7270/Q29G5MDZ 16483774 Breslin, HJ; Cai, C; Miskowski, TA; Coutinho, SV; Zhang, SP; Hornby, P; He, W Johnson & Johnson Pharmaceutical Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50182942 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50182942&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10479670 104067557 CHEMBL208454 ZINC36216171 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50338778 N[C@@H](Cc1ccc(cc1)C(N)=O)C(=O)N1Cc2ccccc2C[C@H]1c1nc(c[nH]1)-c1ccccc1 InChI=1S/C28H27N5O2/c29-23(14-18-10-12-20(13-11-18)26(30)34)28(35)33-17-22-9-5-4-8-21(22)15-25(33)27-31-16-24(32-27)19-6-2-1-3-7-19/h1-13,16,23,25H,14-15,17,29H2,(H2,30,34)(H,31,32)/t23-,25-/m0/s1 YAJPEEZBYVRBIB-ZCYQVOJMSA-N 50182947 4-((S)-2-amino-3-oxo-3-((S)-3-(4-phenyl-1H-imidazol-2-yl)-3,4-dihydroisoquinolin-2(1H)-yl)propyl)benzamide::CHEMBL205388 Mu-type opioid receptor Cavia cutleri 155 ChEMBL 10.1016/j.bmcl.2006.01.082 10.7270/Q29G5MDZ 16483774 Breslin, HJ; Cai, C; Miskowski, TA; Coutinho, SV; Zhang, SP; Hornby, P; He, W Johnson & Johnson Pharmaceutical Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50182947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50182947&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11754240 104067562 CHEMBL205388 ZINC36216183 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50338781 N[C@@H](Cc1ccc(O)cc1)C(=O)N1Cc2ccccc2C[C@H]1c1nc(c[nH]1)-c1ccccc1 InChI=1S/C27H26N4O2/c28-23(14-18-10-12-22(32)13-11-18)27(33)31-17-21-9-5-4-8-20(21)15-25(31)26-29-16-24(30-26)19-6-2-1-3-7-19/h1-13,16,23,25,32H,14-15,17,28H2,(H,29,30)/t23-,25-/m0/s1 SWZLGDBFWBZXTL-ZCYQVOJMSA-N 50154036 (S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-3-(4-phenyl-1H-imidazol-2-yl)-3,4-dihydroisoquinolin-2(1H)-yl)propan-1-one::2-Amino-3-(4-hydroxy-phenyl)-1-[3-(4-phenyl-1H-imidazol-2-yl)-3,4-dihydro-1H-isoquinolin-2-yl]-propan-1-one::CHEMBL361274 Mu-type opioid receptor Cavia cutleri 2445 ChEMBL 10.1016/j.bmcl.2006.01.082 10.7270/Q29G5MDZ 16483774 Breslin, HJ; Cai, C; Miskowski, TA; Coutinho, SV; Zhang, SP; Hornby, P; He, W Johnson & Johnson Pharmaceutical Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50154036 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50154036&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9932852 104041784 CHEMBL361274 ZINC36216109 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50338782 Cc1cc(cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1c1nc(c[nH]1)-c1ccccc1)C(N)=O InChI=1S/C30H31N5O2/c1-18-12-23(28(32)36)13-19(2)24(18)15-25(31)30(37)35-17-22-11-7-6-10-21(22)14-27(35)29-33-16-26(34-29)20-8-4-3-5-9-20/h3-13,16,25,27H,14-15,17,31H2,1-2H3,(H2,32,36)(H,33,34)/t25-,27-/m0/s1 WVYNHNGKKPVPMO-BDYUSTAISA-N 50182943 4-((S)-2-amino-3-oxo-3-((S)-3-(4-phenyl-1H-imidazol-2-yl)-3,4-dihydroisoquinolin-2(1H)-yl)propyl)-3,5-dimethylbenzamide::CHEMBL427214 Mu-type opioid receptor Cavia cutleri 161 ChEMBL 10.1016/j.bmcl.2006.01.082 10.7270/Q29G5MDZ 16483774 Breslin, HJ; Cai, C; Miskowski, TA; Coutinho, SV; Zhang, SP; Hornby, P; He, W Johnson & Johnson Pharmaceutical Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50182943 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50182943&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10255149 104067558 CHEMBL427214 ZINC36216194 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50338783 Cc1[nH]c(nc1-c1ccccc1)[C@@H]1CCCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C24H28N4O2/c1-16-22(18-7-3-2-4-8-18)27-23(26-16)21-9-5-6-14-28(21)24(30)20(25)15-17-10-12-19(29)13-11-17/h2-4,7-8,10-13,20-21,29H,5-6,9,14-15,25H2,1H3,(H,26,27)/t20-,21-/m0/s1 MKNJLSBSRYKNIQ-SFTDATJTSA-N 50154041 (S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-2-(5-methyl-4-phenyl-1H-imidazol-2-yl)piperidin-1-yl)propan-1-one::2-Amino-3-(4-hydroxy-phenyl)-1-[2-(5-methyl-4-phenyl-1H-imidazol-2-yl)-piperidin-1-yl]-propan-1-one::CHEMBL366311 Mu-type opioid receptor Cavia cutleri 142 ChEMBL 10.1016/j.bmcl.2006.01.082 10.7270/Q29G5MDZ 16483774 Breslin, HJ; Cai, C; Miskowski, TA; Coutinho, SV; Zhang, SP; Hornby, P; He, W Johnson & Johnson Pharmaceutical Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50154041 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50154041&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11361718 104041789 CHEMBL366311 ZINC13583526 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50353254 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 InChI=1S/C45H55N7O6/c1-32(49-44(57)39(46)29-35-17-19-38(53)20-18-35)43(56)48-31-41(54)50-40(30-34-13-7-3-8-14-34)45(58)47-25-21-42(55)52(36-15-9-4-10-16-36)37-23-27-51(28-24-37)26-22-33-11-5-2-6-12-33/h2-20,32,37,39-40,53H,21-31,46H2,1H3,(H,47,58)(H,48,56)(H,49,57)(H,50,54)/t32-,39+,40+/m1/s1 WTPXLBTVBOBEDI-JURIQKAMSA-N 50191056 (S)-2-amino-3-(4-hydroxy-phenyl)-N-((R)-1-{[((S)-1-{2-[(1-phenethyl-piperidin-4-yl)-phenyl-carbamoyl]-ethylcarbamoyl}-2-phenyl-ethylcarbamoyl)-methyl]-carbamoyl}-ethyl)-propionamide::CHEMBL214022 Mu-type opioid receptor Cavia cutleri 42 ChEMBL 10.1016/j.bmcl.2006.06.040 10.7270/Q24B30Z0 16828552 Petrov, RR; Vardanyan, RS; Lee, YS; Ma, SW; Davis, P; Begay, LJ; Lai, JY; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50191056 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50191056&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16046123 104074222 CHEMBL214022 ZINC95542936 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50349089 CN(C)c1ccc2cc3C(=O)N(CC(NC(=O)CCCCCNC(=O)[C@H](CCC(O)=O)NC(=O)C4Cc5ccccc5CN4C(=O)[C@@H](N)Cc4c(C)cc(O)cc4C)C(N)=O)C(=O)c3cc2c1 InChI=1S/C49H58N8O10/c1-27-18-34(58)19-28(2)35(27)24-38(50)49(67)56-25-31-11-8-7-10-29(31)23-41(56)46(64)54-39(15-16-43(60)61)45(63)52-17-9-5-6-12-42(59)53-40(44(51)62)26-57-47(65)36-21-30-13-14-33(55(3)4)20-32(30)22-37(36)48(57)66/h7-8,10-11,13-14,18-22,38-41,58H,5-6,9,12,15-17,23-26,50H2,1-4H3,(H2,51,62)(H,52,63)(H,53,59)(H,54,64)(H,60,61)/t38-,39-,40?,41?/m0/s1 DURKEIXAKJIEGD-JHIBKCPMSA-N 50188534 (H-Dmt-Tic-Glu-NH-(CH(2))(5)-CO-Dap(6DMN)-NH(2)::CHEMBL426320 Mu-type opioid receptor Cavia cutleri 244 ChEMBL 10.1021/jm060343t 10.7270/Q25M65B6 16759107 Vazquez, ME; Blanco, JB; Salvadori, S; Trapella, C; Argazzi, R; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Negri, L; Giannini, E; Lattanzi, R; Colucci, M; Balboni, G Universidad de Santiago de Compostela http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50188534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50188534&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44412158 104072322 CHEMBL426320 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50349091 CN(C)c1ccc2cc3C(=O)N(CC(NC(=O)[C@@H]4CCCN4C(=O)[C@@H](N)Cc4ccc(O)cc4)C(=O)N[C@@H](Cc4ccccc4)C(N)=O)C(=O)c3cc2c1 InChI=1S/C40H43N7O7/c1-45(2)27-13-12-25-20-29-30(21-26(25)19-27)39(53)47(38(29)52)22-33(36(50)43-32(35(42)49)18-23-7-4-3-5-8-23)44-37(51)34-9-6-16-46(34)40(54)31(41)17-24-10-14-28(48)15-11-24/h3-5,7-8,10-15,19-21,31-34,48H,6,9,16-18,22,41H2,1-2H3,(H2,42,49)(H,43,50)(H,44,51)/t31-,32-,33?,34-/m0/s1 OHGKVUSMHZDAKH-SHROADRVSA-N 50188536 CHEMBL207661::H-Tyr-Pro-Dap(6DMN)-Phe-NH2 Mu-type opioid receptor Cavia cutleri 389 ChEMBL 10.1021/jm060343t 10.7270/Q25M65B6 16759107 Vazquez, ME; Blanco, JB; Salvadori, S; Trapella, C; Argazzi, R; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Negri, L; Giannini, E; Lattanzi, R; Colucci, M; Balboni, G Universidad de Santiago de Compostela http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50188536 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50188536&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44412206 104072324 CHEMBL207661 ZINC49938014 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50349096 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCCCCCNC(=S)N=C1C=CC(C(=C1)C(O)=O)=C1c2ccc(O)cc2Oc2cc(O)ccc12 InChI=1S/C58H59N7O10S/c59-46(29-37-16-19-39(66)20-17-37)56(72)65-28-10-15-49(65)55(71)64-48(31-36-13-6-2-7-14-36)54(70)63-47(30-35-11-4-1-5-12-35)53(69)60-26-8-3-9-27-61-58(76)62-38-18-23-42(45(32-38)57(73)74)52-43-24-21-40(67)33-50(43)75-51-34-41(68)22-25-44(51)52/h1-2,4-7,11-14,16-25,32-34,46-49,66-68H,3,8-10,15,26-31,59H2,(H,60,69)(H,61,76)(H,63,70)(H,64,71)(H,73,74)/t46-,47-,48-,49-/m0/s1 WMUDXJRYJFJINT-HVRJTYTESA-N 50188535 CHEMBL219407::H-Tyr-Pro-Phe-Phe-NH-(CH2)5-NH-(C=S)-NH-fluorescein Mu-type opioid receptor Cavia cutleri 120 ChEMBL 10.1021/jm060343t 10.7270/Q25M65B6 16759107 Vazquez, ME; Blanco, JB; Salvadori, S; Trapella, C; Argazzi, R; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Negri, L; Giannini, E; Lattanzi, R; Colucci, M; Balboni, G Universidad de Santiago de Compostela http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50188535 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50188535&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11593284 104072323 CHEMBL219407 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50349101 CN(C)c1ccc2cc3C(=O)N(CC(NC(=O)CCCCCNC(=O)[C@H](Cc4ccccc4)NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@@H]4CCCN4C(=O)[C@@H](N)Cc4ccc(O)cc4)C(N)=O)C(=O)c3cc2c1 InChI=1S/C55H63N9O9/c1-62(2)39-22-21-37-31-41-42(32-38(37)30-39)54(72)64(53(41)71)33-46(49(57)67)59-48(66)18-10-5-11-25-58-50(68)44(28-34-13-6-3-7-14-34)60-51(69)45(29-35-15-8-4-9-16-35)61-52(70)47-17-12-26-63(47)55(73)43(56)27-36-19-23-40(65)24-20-36/h3-4,6-9,13-16,19-24,30-32,43-47,65H,5,10-12,17-18,25-29,33,56H2,1-2H3,(H2,57,67)(H,58,68)(H,59,66)(H,60,69)(H,61,70)/t43-,44-,45-,46?,47-/m0/s1 FATMKOSWYXDNJL-FCTRPSMQSA-N 50188533 CHEMBL411335::H-Tyr-Pro-Phe-Phe-NH-(CH2)5-(C=O)-Dap(6DMN)-NH2 Mu-type opioid receptor Cavia cutleri 253 ChEMBL 10.1021/jm060343t 10.7270/Q25M65B6 16759107 Vazquez, ME; Blanco, JB; Salvadori, S; Trapella, C; Argazzi, R; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Negri, L; Giannini, E; Lattanzi, R; Colucci, M; Balboni, G Universidad de Santiago de Compostela http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50188533 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50188533&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44412234 104072321 CHEMBL411335 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50349102 CN(C)c1ccc2cc3C(=O)N(CC(NC(=O)[C@H](CCC(O)=O)NC(=O)C4Cc5ccccc5C(N4)C(=O)[C@@H](N)Cc4c(C)cc(O)cc4C)C(N)=O)C(=O)c3cc2c1 InChI=1S/C43H47N7O9/c1-21-13-27(51)14-22(2)29(21)19-32(44)38(54)37-28-8-6-5-7-24(28)18-34(46-37)41(57)47-33(11-12-36(52)53)40(56)48-35(39(45)55)20-50-42(58)30-16-23-9-10-26(49(3)4)15-25(23)17-31(30)43(50)59/h5-10,13-17,32-35,37,46,51H,11-12,18-20,44H2,1-4H3,(H2,45,55)(H,47,57)(H,48,56)(H,52,53)/t32-,33-,34?,35?,37?/m0/s1 XJJAERVDDMSANL-TXQDRJNYSA-N 50188537 CHEMBL208916::H-Dmt-Tic-Glu-Dap(6DMN)-NH(2) Mu-type opioid receptor Cavia cutleri 100 ChEMBL 10.1021/jm060343t 10.7270/Q25M65B6 16759107 Vazquez, ME; Blanco, JB; Salvadori, S; Trapella, C; Argazzi, R; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Negri, L; Giannini, E; Lattanzi, R; Colucci, M; Balboni, G Universidad de Santiago de Compostela http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50188537 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50188537&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44412290 104072325 CHEMBL208916 ZINC95606888 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50348305 CNC[C@@H]1CCCN1C[C@H](Cc1ccccc1)N(C)C[C@H](Cc1ccc(O)cc1)N(C)C[C@H](Cc1ccc(O)cc1)NC InChI=1S/C36H53N5O2/c1-37-24-32-11-8-20-41(32)27-34(22-28-9-6-5-7-10-28)40(4)26-33(23-30-14-18-36(43)19-15-30)39(3)25-31(38-2)21-29-12-16-35(42)17-13-29/h5-7,9-10,12-19,31-34,37-38,42-43H,8,11,20-27H2,1-4H3/t31-,32-,33-,34-/m0/s1 KXVDQEBWXOUYEM-CUPIEXAXSA-N 50188156 4-[(2S)-3-{[(2S)-1-(4-hydroxyphenyl)-3-{methyl[(2S)-1-[(2S)-2-[(methylamino)methyl]pyrrolidin-1-yl]-3-phenylpropan-2-yl]amino}propan-2-yl](methyl)amino}-2-(methylamino)propyl]phenol::CHEMBL215595 Mu-type opioid receptor Cavia cutleri 2 ChEMBL 10.1016/j.bmcl.2006.05.053 10.7270/Q2028R47 16750366 Nefzi, A; Ostresh, JM; Appel, JR; Bidlack, J; Dooley, CT; Houghten, RA Institute for Molecular Studies http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50188156 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50188156&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44415236 104071982 CHEMBL215595 ZINC38147600 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50348316 NC[C@@H]1CCCN1C[C@H](Cc1ccccc1)NC[C@H](Cc1ccc(O)cc1)NC[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C32H45N5O2/c33-20-30-7-4-16-37(30)23-29(19-24-5-2-1-3-6-24)36-22-28(18-26-10-14-32(39)15-11-26)35-21-27(34)17-25-8-12-31(38)13-9-25/h1-3,5-6,8-15,27-30,35-36,38-39H,4,7,16-23,33-34H2/t27-,28-,29-,30-/m0/s1 NTXYKPCTOOPADC-KRCBVYEFSA-N 50188167 4-[(2S)-2-amino-3-{[(2S)-1-{[(2S)-1-[(2S)-2-(aminomethyl)pyrrolidin-1-yl]-3-phenylpropan-2-yl]amino}-3-(4-hydroxyphenyl)propan-2-yl]amino}propyl]phenol::CHEMBL213069 Mu-type opioid receptor Cavia cutleri 6 ChEMBL 10.1016/j.bmcl.2006.05.053 10.7270/Q2028R47 16750366 Nefzi, A; Ostresh, JM; Appel, JR; Bidlack, J; Dooley, CT; Houghten, RA Institute for Molecular Studies http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50188167 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50188167&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44415120 104071993 CHEMBL213069 ZINC38147603 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50359078 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCCc1nc(C)c(CCCNC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)[nH]c1=O InChI=1S/C34H48N6O5/c1-19-13-24(41)14-20(2)26(19)17-28(35)32(43)37-11-7-6-9-31-34(45)40-30(23(5)39-31)10-8-12-38-33(44)29(36)18-27-21(3)15-25(42)16-22(27)4/h13-16,28-29,41-42H,6-12,17-18,35-36H2,1-5H3,(H,37,43)(H,38,44)(H,40,45)/t28-,29-/m0/s1 JZVUQVMVBXOURL-VMPREFPWSA-N 50194487 3-[4'-(H-Dmt)-aminobutyl]-6-[3'-(H-Dmt)-aminopropyl]-5-methyl-2(1H)-pyrazinone::CHEMBL376061 Mu-type opioid receptor Cavia cutleri 1.79 ChEMBL 10.1016/j.bmcl.2006.08.079 10.7270/Q26Q1WWH 16949282 Shiotani, K; Li, T; Miyazaki, A; Tsuda, Y; Bryant, SD; Ambo, A; Sasaki, Y; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50194487 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50194487&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44419590 104076771 CHEMBL376061 ZINC36216384 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50359086 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCCc1[nH]c(=O)c(CCCNC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)nc1C InChI=1S/C34H48N6O5/c1-19-13-24(41)14-20(2)26(19)17-28(35)32(43)37-11-7-6-9-30-23(5)39-31(34(45)40-30)10-8-12-38-33(44)29(36)18-27-21(3)15-25(42)16-22(27)4/h13-16,28-29,41-42H,6-12,17-18,35-36H2,1-5H3,(H,37,43)(H,38,44)(H,40,45)/t28-,29-/m0/s1 AIOLFDZVYRFPMH-VMPREFPWSA-N 50194488 6-[4'-(H-Dmt)-aminobutyl]-3-[3'-(H-Dmt)-aminopropyl]-5-methyl-2(1H)-pyrazinone::CHEMBL385779 Mu-type opioid receptor Cavia cutleri 4.93 ChEMBL 10.1016/j.bmcl.2006.08.079 10.7270/Q26Q1WWH 16949282 Shiotani, K; Li, T; Miyazaki, A; Tsuda, Y; Bryant, SD; Ambo, A; Sasaki, Y; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50194488 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50194488&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44419723 104076772 CHEMBL385779 ZINC36216381 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50348349 CCNC[C@@H]1CCCN1C[C@H](Cc1ccccc1)N(CC)C[C@H](Cc1ccc(O)cc1)N(CC)C[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C38H57N5O2/c1-4-40-26-34-13-10-22-43(34)29-36(24-30-11-8-7-9-12-30)42(6-3)28-35(25-32-16-20-38(45)21-17-32)41(5-2)27-33(39)23-31-14-18-37(44)19-15-31/h7-9,11-12,14-21,33-36,40,44-45H,4-6,10,13,22-29,39H2,1-3H3/t33-,34-,35-,36-/m0/s1 RAUSFOOIAODGPX-ZYADHFCISA-N 50188193 4-[(2S)-2-amino-3-{ethyl[(2S)-1-{ethyl[(2S)-1-[(2S)-2-[(ethylamino)methyl]pyrrolidin-1-yl]-3-phenylpropan-2-yl]amino}-3-(4-hydroxyphenyl)propan-2-yl]amino}propyl]phenol::CHEMBL214581 Mu-type opioid receptor Cavia cutleri 45 ChEMBL 10.1016/j.bmcl.2006.05.053 10.7270/Q2028R47 16750366 Nefzi, A; Ostresh, JM; Appel, JR; Bidlack, J; Dooley, CT; Houghten, RA Institute for Molecular Studies http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50188193 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50188193&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44415079 104072019 CHEMBL214581 ZINC38147602 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50348367 CNC[C@@H]1CCCN1C[C@H](Cc1ccccc1)N(C)C[C@H](Cc1ccc(O)cc1)N(C)C[C@H](Cc1ccc(O)cc1)N(C)C InChI=1S/C37H55N5O2/c1-38-25-32-12-9-21-42(32)28-35(23-29-10-7-6-8-11-29)41(5)27-34(24-31-15-19-37(44)20-16-31)40(4)26-33(39(2)3)22-30-13-17-36(43)18-14-30/h6-8,10-11,13-20,32-35,38,43-44H,9,12,21-28H2,1-5H3/t32-,33-,34-,35-/m0/s1 QWTKIROLSYOMPY-BBACVFHCSA-N 50188203 4-[(2S)-2-(dimethylamino)-3-{[(2S)-1-(4-hydroxyphenyl)-3-{methyl[(2S)-1-[(2S)-2-[(methylamino)methyl]pyrrolidin-1-yl]-3-phenylpropan-2-yl]amino}propan-2-yl](methyl)amino}propyl]phenol::CHEMBL215809 Mu-type opioid receptor Cavia cutleri 8 ChEMBL 10.1016/j.bmcl.2006.05.053 10.7270/Q2028R47 16750366 Nefzi, A; Ostresh, JM; Appel, JR; Bidlack, J; Dooley, CT; Houghten, RA Institute for Molecular Studies http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50188203 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50188203&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44415238 104072029 CHEMBL215809 ZINC38147601 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50348374 N[C@H](CN(Cc1ccccc1)[C@H](CN(Cc1ccccc1)[C@H](CN1CCC[C@H]1CNCc1ccccc1)Cc1ccccc1)Cc1ccc(O)cc1)Cc1ccc(O)cc1 InChI=1S/C53H63N5O2/c54-48(32-43-23-27-52(59)28-24-43)39-57(37-46-18-9-3-10-19-46)51(34-44-25-29-53(60)30-26-44)41-58(38-47-20-11-4-12-21-47)50(33-42-14-5-1-6-15-42)40-56-31-13-22-49(56)36-55-35-45-16-7-2-8-17-45/h1-12,14-21,23-30,48-51,55,59-60H,13,22,31-41,54H2/t48-,49-,50-,51-/m0/s1 IPFNKYLAHKEYLB-KBQHETQHSA-N 50188205 4-[(2S)-2-amino-3-{benzyl[(2S)-1-{benzyl[(2S)-1-[(2S)-2-[(benzylamino)methyl]pyrrolidin-1-yl]-3-phenylpropan-2-yl]amino}-3-(4-hydroxyphenyl)propan-2-yl]amino}propyl]phenol::CHEMBL377733 Mu-type opioid receptor Cavia cutleri 4464 ChEMBL 10.1016/j.bmcl.2006.05.053 10.7270/Q2028R47 16750366 Nefzi, A; Ostresh, JM; Appel, JR; Bidlack, J; Dooley, CT; Houghten, RA Institute for Molecular Studies http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50188205 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50188205&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44415080 104072031 CHEMBL377733 ZINC95612716 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50348380 N[C@H](CN(Cc1ccc2ccccc2c1)[C@H](CN(Cc1ccc2ccccc2c1)[C@H](CN1CCC[C@H]1CNCc1ccc2ccccc2c1)Cc1ccccc1)Cc1ccc(O)cc1)Cc1ccc(O)cc1 InChI=1S/C65H69N5O2/c66-60(38-49-23-30-64(71)31-24-49)45-69(43-52-21-28-55-14-5-8-17-58(55)36-52)63(40-50-25-32-65(72)33-26-50)47-70(44-53-22-29-56-15-6-9-18-59(56)37-53)62(39-48-11-2-1-3-12-48)46-68-34-10-19-61(68)42-67-41-51-20-27-54-13-4-7-16-57(54)35-51/h1-9,11-18,20-33,35-37,60-63,67,71-72H,10,19,34,38-47,66H2/t60-,61-,62-,63-/m0/s1 GMFYBFACGRCIKD-RLANMGNTSA-N 50188208 4-[(2S)-2-amino-3-{[(2S)-1-(4-hydroxyphenyl)-3-[(naphthalen-2-ylmethyl)[(2S)-1-[(2S)-2-{[(naphthalen-2-ylmethyl)amino]methyl}pyrrolidin-1-yl]-3-phenylpropan-2-yl]amino]propan-2-yl](naphthalen-2-ylmethyl)amino}propyl]phenol::CHEMBL269502 Mu-type opioid receptor Cavia cutleri 18589 ChEMBL 10.1016/j.bmcl.2006.05.053 10.7270/Q2028R47 16750366 Nefzi, A; Ostresh, JM; Appel, JR; Bidlack, J; Dooley, CT; Houghten, RA Institute for Molecular Studies http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50188208 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50188208&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44415099 104072034 CHEMBL269502 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50348384 CNC[C@@H]1CCCN1C[C@H](Cc1ccccc1)N(C)C[C@H](Cc1ccc(O)cc1)N(C)C[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C35H51N5O2/c1-37-23-31-10-7-19-40(31)26-33(21-27-8-5-4-6-9-27)39(3)25-32(22-29-13-17-35(42)18-14-29)38(2)24-30(36)20-28-11-15-34(41)16-12-28/h4-6,8-9,11-18,30-33,37,41-42H,7,10,19-26,36H2,1-3H3/t30-,31-,32-,33-/m0/s1 DGPYFRPOLFFYGM-YRCZKMHPSA-N 50188210 4-[(2S)-2-amino-3-{[(2S)-1-(4-hydroxyphenyl)-3-{methyl[(2S)-1-[(2S)-2-[(methylamino)methyl]pyrrolidin-1-yl]-3-phenylpropan-2-yl]amino}propan-2-yl](methyl)amino}propyl]phenol::CHEMBL384750 Mu-type opioid receptor Cavia cutleri 13 ChEMBL 10.1016/j.bmcl.2006.05.053 10.7270/Q2028R47 16750366 Nefzi, A; Ostresh, JM; Appel, JR; Bidlack, J; Dooley, CT; Houghten, RA Institute for Molecular Studies http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50188210 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50188210&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44415098 104072036 CHEMBL384750 ZINC38147599 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50376053 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CCCC[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC1=O)C(N)=O InChI=1S/C28H36N6O6/c29-20(14-18-10-12-19(35)13-11-18)26(38)34-22-9-5-4-8-21(25(30)37)33-28(40)23(15-17-6-2-1-3-7-17)32-24(36)16-31-27(22)39/h1-3,6-7,10-13,20-23,35H,4-5,8-9,14-16,29H2,(H2,30,37)(H,31,39)(H,32,36)(H,33,40)(H,34,38)/t20-,21-,22+,23-/m0/s1 RIGPFFUSPNYWOF-GPJHCHHRSA-N 50205831 CHEMBL387159::H-Tyr-c[D-Allylgly-Gly-Phe-L-Allylgly]NH2 Mu-type opioid receptor Cavia cutleri 1.02 ChEMBL 10.1021/jm061294n 10.7270/Q22F7N41 17315860 Berezowska, I; Chung, NN; Lemieux, C; Wilkes, BC; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50205831 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50205831&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16116219 104084109 CHEMBL387159 ZINC36216404 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50376056 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CCCC[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC1=O)C(N)=O InChI=1S/C28H36N6O6/c29-20(14-18-10-12-19(35)13-11-18)26(38)34-22-9-5-4-8-21(25(30)37)33-28(40)23(15-17-6-2-1-3-7-17)32-24(36)16-31-27(22)39/h1-3,6-7,10-13,20-23,35H,4-5,8-9,14-16,29H2,(H2,30,37)(H,31,39)(H,32,36)(H,33,40)(H,34,38)/t20-,21+,22+,23-/m0/s1 RIGPFFUSPNYWOF-AFXVXQJMSA-N 50205833 CHEMBL222830::H-Tyr-c[D-Allylgly-Gly-Phe-D-Allylgly]NH2 Mu-type opioid receptor Cavia cutleri 11.2 ChEMBL 10.1021/jm061294n 10.7270/Q22F7N41 17315860 Berezowska, I; Chung, NN; Lemieux, C; Wilkes, BC; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50205833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50205833&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16116222 104084111 CHEMBL222830 ZINC36216396 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50376062 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC1=O)C(N)=O InChI=1S/C26H32N6O6S2/c27-18(10-16-6-8-17(33)9-7-16)24(36)32-21-14-40-39-13-20(23(28)35)31-26(38)19(11-15-4-2-1-3-5-15)30-22(34)12-29-25(21)37/h1-9,18-21,33H,10-14,27H2,(H2,28,35)(H,29,37)(H,30,34)(H,31,38)(H,32,36)/t18-,19-,20-,21-/m0/s1 VUVASMYWPNXOGI-TUFLPTIASA-N 50205832 CHEMBL220327::H-Tyr-c[D-Cys-Gly-Phe-D-Cys]NH2 Mu-type opioid receptor Cavia cutleri 1.3 ChEMBL 10.1021/jm061294n 10.7270/Q22F7N41 17315860 Berezowska, I; Chung, NN; Lemieux, C; Wilkes, BC; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50205832 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50205832&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44420667 104084110 CHEMBL220327 ZINC36216399 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50376071 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CC=CC[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC1=O)C(N)=O InChI=1S/C28H34N6O6/c29-20(14-18-10-12-19(35)13-11-18)26(38)34-22-9-5-4-8-21(25(30)37)33-28(40)23(15-17-6-2-1-3-7-17)32-24(36)16-31-27(22)39/h1-7,10-13,20-23,35H,8-9,14-16,29H2,(H2,30,37)(H,31,39)(H,32,36)(H,33,40)(H,34,38)/t20-,21-,22+,23-/m0/s1 UYBFKIDGDVZVFM-GPJHCHHRSA-N 50205834 CHEMBL220333::CHEMBL223244::H-Tyr-c[D-Allylgly-Gly-Phe-L-Allylgly]NH2 Mu-type opioid receptor Cavia cutleri 1.81 ChEMBL 10.1021/jm061294n 10.7270/Q22F7N41 17315860 Berezowska, I; Chung, NN; Lemieux, C; Wilkes, BC; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50205834 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50205834&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16116089 104084112 CHEMBL220333CHEMBL223244 ZINC36216401 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50376074 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CC=CC[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC1=O)C(N)=O InChI=1S/C28H34N6O6/c29-20(14-18-10-12-19(35)13-11-18)26(38)34-22-9-5-4-8-21(25(30)37)33-28(40)23(15-17-6-2-1-3-7-17)32-24(36)16-31-27(22)39/h1-7,10-13,20-23,35H,8-9,14-16,29H2,(H2,30,37)(H,31,39)(H,32,36)(H,33,40)(H,34,38)/t20-,21+,22+,23-/m0/s1 UYBFKIDGDVZVFM-AFXVXQJMSA-N 50205828 CHEMBL220219::CHEMBL373796::H-Tyr-c[D-Allylgly-Gly-Phe-D-Allylgly]NH2 Mu-type opioid receptor Cavia cutleri 11.9 ChEMBL 10.1021/jm061294n 10.7270/Q22F7N41 17315860 Berezowska, I; Chung, NN; Lemieux, C; Wilkes, BC; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50205828 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50205828&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16116221 104084106 CHEMBL373796CHEMBL220219 ZINC36216392 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50376075 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H]1CSSC[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC1=O)C(N)=O InChI=1S/C26H32N6O6S2/c27-18(10-16-6-8-17(33)9-7-16)24(36)32-21-14-40-39-13-20(23(28)35)31-26(38)19(11-15-4-2-1-3-5-15)30-22(34)12-29-25(21)37/h1-9,18-21,33H,10-14,27H2,(H2,28,35)(H,29,37)(H,30,34)(H,31,38)(H,32,36)/t18-,19-,20+,21-/m0/s1 VUVASMYWPNXOGI-BURNTYAHSA-N 50205830 CHEMBL373572::H-Tyr-c[D-Cys-Gly-Phe-L-Cys]NH2 Mu-type opioid receptor Cavia cutleri 1.65 ChEMBL 10.1021/jm061294n 10.7270/Q22F7N41 17315860 Berezowska, I; Chung, NN; Lemieux, C; Wilkes, BC; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50205830 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50205830&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44420674 104084108 CHEMBL373572 ZINC36216406 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50376076 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CC=CC[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC1=O)C(N)=O InChI=1S/C28H34N6O6/c29-20(14-18-10-12-19(35)13-11-18)26(38)34-22-9-5-4-8-21(25(30)37)33-28(40)23(15-17-6-2-1-3-7-17)32-24(36)16-31-27(22)39/h1-7,10-13,20-23,35H,8-9,14-16,29H2,(H2,30,37)(H,31,39)(H,32,36)(H,33,40)(H,34,38)/t20-,21-,22+,23-/m0/s1 UYBFKIDGDVZVFM-GPJHCHHRSA-N 50205834 CHEMBL220333::CHEMBL223244::H-Tyr-c[D-Allylgly-Gly-Phe-L-Allylgly]NH2 Mu-type opioid receptor Cavia cutleri 0.898 ChEMBL 10.1021/jm061294n 10.7270/Q22F7N41 17315860 Berezowska, I; Chung, NN; Lemieux, C; Wilkes, BC; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50205834 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50205834&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16116089 104084112 CHEMBL220333CHEMBL223244 ZINC36216401 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50376078 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CC=CC[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC1=O)C(N)=O InChI=1S/C28H34N6O6/c29-20(14-18-10-12-19(35)13-11-18)26(38)34-22-9-5-4-8-21(25(30)37)33-28(40)23(15-17-6-2-1-3-7-17)32-24(36)16-31-27(22)39/h1-7,10-13,20-23,35H,8-9,14-16,29H2,(H2,30,37)(H,31,39)(H,32,36)(H,33,40)(H,34,38)/t20-,21+,22+,23-/m0/s1 UYBFKIDGDVZVFM-AFXVXQJMSA-N 50205828 CHEMBL220219::CHEMBL373796::H-Tyr-c[D-Allylgly-Gly-Phe-D-Allylgly]NH2 Mu-type opioid receptor Cavia cutleri 5.63 ChEMBL 10.1021/jm061294n 10.7270/Q22F7N41 17315860 Berezowska, I; Chung, NN; Lemieux, C; Wilkes, BC; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50205828 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50205828&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16116221 104084106 CHEMBL373796CHEMBL220219 ZINC36216392 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50377257 CCC(=O)N(C1CCN(CC1)C(=O)[C@@H](N)[C@H](C)c1c(C)cc(O)cc1C)c1ccccc1 InChI=1S/C26H35N3O3/c1-5-23(31)29(20-9-7-6-8-10-20)21-11-13-28(14-12-21)26(32)25(27)19(4)24-17(2)15-22(30)16-18(24)3/h6-10,15-16,19,21,25,30H,5,11-14,27H2,1-4H3/t19-,25+/m1/s1 PFMOTJNRKNDBQA-CLOONOSVSA-N 50206643 CHEMBL390480::N-(1-((2S,3R)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)butanoyl)piperidin-4-yl)-N-phenylpropionamide Mu-type opioid receptor Cavia cutleri 3300 ChEMBL 10.1016/j.bmcl.2007.01.114 10.7270/Q270813K 17329100 Lee, YS; Nyberg, J; Moye, S; Agnes, RS; Davis, P; Ma, SW; Lai, J; Porreca, F; Vardanyan, R; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50206643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50206643&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44425366 104084612 CHEMBL390480 ZINC28703147 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50369806 CCC(=O)N(c1ccccc1)C1(CCN(CCc2ccccc2)CC1)C(=O)OC InChI=1S/C24H30N2O3/c1-3-22(27)26(21-12-8-5-9-13-21)24(23(28)29-2)15-18-25(19-16-24)17-14-20-10-6-4-7-11-20/h4-13H,3,14-19H2,1-2H3 YDSDEBIZUNNPOB-UHFFFAOYSA-N 50012477 1-Phenethyl-4-(phenyl-propionyl-amino)-piperidine-4-carboxylic acid methyl ester::1-Phenethyl-4-(phenyl-propionyl-amino)-piperidine-4-carboxylic acid methyl ester(Carefentanil)::CARFENTANIL::CHEMBL290429::Carfentanil1-Phenethyl-4-(phenyl-propionyl-amino)-piperidine-4-carboxylic acid methyl ester Mu-type opioid receptor Cavia cutleri 0.019000 ChEMBL 10.1016/j.bmc.2014.07.033 10.7270/Q2P270WT 25129170 Weltrowska, G; Lemieux, C; Chung, NN; Guo, JJ; Wilkes, BC; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012477 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012477&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 62156 103924756 61084 CHEMBL290429 DB01535 ZINC04215196 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50369807 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 29 ChEMBL 10.1016/j.bmc.2014.07.033 10.7270/Q2P270WT 25129170 Weltrowska, G; Lemieux, C; Chung, NN; Guo, JJ; Wilkes, BC; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50366822 Cc1cc(O)cc(C)c1C[C@H](NCC=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C37H45N5O5/c1-4-17-39-32(23-29-24(2)19-28(43)20-25(29)3)37(47)42-18-11-16-33(42)36(46)41-31(22-27-14-9-6-10-15-27)35(45)40-30(34(38)44)21-26-12-7-5-8-13-26/h4-10,12-15,19-20,30-33,39,43H,1,11,16-18,21-23H2,2-3H3,(H2,38,44)(H,40,45)(H,41,46)/t30-,31-,32-,33-/m0/s1 PBEKHMJUJBBTHM-YRCZKMHPSA-N 50199861 (S)-1-((S)-2-(allylamino)-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)pyrrolidine-2-carboxamide::CHEMBL412922 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1016/j.bmc.2006.11.019 10.7270/Q2348K1F 17142049 Li, T; Jinsmaa, Y; Nedachi, M; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Bryant, SD; Marczak, E; Li, Q; Swartzwelder, HS; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199861&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15981504 104080341 CHEMBL412922 ZINC28816955 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50366825 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C34H38N6O5/c35-26(17-22-12-14-24(41)15-13-22)34(45)40-16-6-11-30(40)33(44)39-29(19-23-20-37-27-10-5-4-9-25(23)27)32(43)38-28(31(36)42)18-21-7-2-1-3-8-21/h1-5,7-10,12-15,20,26,28-30,37,41H,6,11,16-19,35H2,(H2,36,42)(H,38,43)(H,39,44)/t26-,28-,29-,30-/m0/s1 ZEXLJFNSKAHNFH-SYKYGTKKSA-N 50095155 (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide::(S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxamide::1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [1-((S)-(S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide::1-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [1-(1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide::CHEMBL316446::ENDOMORPHIN-1::H-Tyr-Pro-Trp-Phe-NH2::Tyr-Pro-Trp-Phe-NH2::YPWF-NH2::endomorphin -1 Mu-type opioid receptor Cavia cutleri 4.03 ChEMBL 10.1016/j.bmc.2006.11.019 10.7270/Q2348K1F 17142049 Li, T; Jinsmaa, Y; Nedachi, M; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Bryant, SD; Marczak, E; Li, Q; Swartzwelder, HS; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095155&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311080 103992914 CHEMBL316446 1623 ZINC14951658 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50366828 Cc1cc(O)cc(C)c1C[C@H](NCC=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC=C InChI=1S/C40H49N5O5/c1-5-19-41-35(26-32-27(3)22-31(46)23-28(32)4)40(50)45-21-13-18-36(45)39(49)44-34(25-30-16-11-8-12-17-30)38(48)43-33(37(47)42-20-6-2)24-29-14-9-7-10-15-29/h5-12,14-17,22-23,33-36,41,46H,1-2,13,18-21,24-26H2,3-4H3,(H,42,47)(H,43,48)(H,44,49)/t33-,34-,35-,36-/m0/s1 LRLJIVMILJUGBU-ZYADHFCISA-N 50199864 (S)-N-((S)-1-((S)-1-(allylamino)-1-oxo-3-phenylpropan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-1-((S)-2-(allylamino)-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)pyrrolidine-2-carboxamide::CHEMBL397176 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1016/j.bmc.2006.11.019 10.7270/Q2348K1F 17142049 Li, T; Jinsmaa, Y; Nedachi, M; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Bryant, SD; Marczak, E; Li, Q; Swartzwelder, HS; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199864&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44429952 104080344 CHEMBL397176 ZINC28816953 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50373103 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C34H38N6O5/c35-26(17-22-12-14-24(41)15-13-22)34(45)40-16-6-11-30(40)33(44)39-29(19-23-20-37-27-10-5-4-9-25(23)27)32(43)38-28(31(36)42)18-21-7-2-1-3-8-21/h1-5,7-10,12-15,20,26,28-30,37,41H,6,11,16-19,35H2,(H2,36,42)(H,38,43)(H,39,44)/t26-,28-,29-,30-/m0/s1 ZEXLJFNSKAHNFH-SYKYGTKKSA-N 50095155 (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide::(S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxamide::1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [1-((S)-(S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide::1-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [1-(1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide::CHEMBL316446::ENDOMORPHIN-1::H-Tyr-Pro-Trp-Phe-NH2::Tyr-Pro-Trp-Phe-NH2::YPWF-NH2::endomorphin -1 Mu-type opioid receptor Cavia cutleri 17 ChEMBL 10.1021/jm060998u 10.7270/Q28915JT 17266203 Fichna, J; do-Rego, JC; Chung, NN; Lemieux, C; Schiller, PW; Poels, J; Broeck, JV; Costentin, J; Janecka, A Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095155&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311080 103992914 CHEMBL316446 1623 ZINC14951658 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50373104 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1cccc2ccccc12)C(N)=O InChI=1S/C38H40N6O5/c39-30(19-23-14-16-27(45)17-15-23)38(49)44-18-6-13-34(44)37(48)43-33(21-26-22-41-31-12-4-3-11-29(26)31)36(47)42-32(35(40)46)20-25-9-5-8-24-7-1-2-10-28(24)25/h1-5,7-12,14-17,22,30,32-34,41,45H,6,13,18-21,39H2,(H2,40,46)(H,42,47)(H,43,48)/t30-,32+,33-,34-/m0/s1 NTJDGOIOMBYDLX-SSGXOEHOSA-N 50203822 CHEMBL219108::Tyr-Pro-Trp-D-1-Nal-NH2 Mu-type opioid receptor Cavia cutleri 4180 ChEMBL 10.1021/jm060998u 10.7270/Q28915JT 17266203 Fichna, J; do-Rego, JC; Chung, NN; Lemieux, C; Schiller, PW; Poels, J; Broeck, JV; Costentin, J; Janecka, A Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203822&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16105558 104082780 CHEMBL219108 ZINC49942436 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50366833 Oc1ccc(C[C@H](NCC=C)C(=O)NCCCCCCNC(=O)[C@H](Cc2ccc(O)cc2)NCC=C)cc1 InChI=1S/C30H42N4O4/c1-3-17-31-27(21-23-9-13-25(35)14-10-23)29(37)33-19-7-5-6-8-20-34-30(38)28(32-18-4-2)22-24-11-15-26(36)16-12-24/h3-4,9-16,27-28,31-32,35-36H,1-2,5-8,17-22H2,(H,33,37)(H,34,38)/t27-,28-/m0/s1 LRTMETRSFGLQOB-NSOVKSMOSA-N 50199862 (S)-2-allylamino-N-{6-[(S)-2-allylamino-3-(4-hydroxy-phenyl)-propionylamino]-hexyl}-3-(4-hydroxy-phenyl)-propionamide::CHEMBL232303 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1016/j.bmc.2006.11.019 10.7270/Q2348K1F 17142049 Li, T; Jinsmaa, Y; Nedachi, M; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Bryant, SD; Marczak, E; Li, Q; Swartzwelder, HS; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199862&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44429954 104080342 CHEMBL232303 ZINC28816964 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50366838 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C36H42N6O5/c1-21-15-25(43)16-22(2)27(21)19-28(37)36(47)42-14-8-13-32(42)35(46)41-31(18-24-20-39-29-12-7-6-11-26(24)29)34(45)40-30(33(38)44)17-23-9-4-3-5-10-23/h3-7,9-12,15-16,20,28,30-32,39,43H,8,13-14,17-19,37H2,1-2H3,(H2,38,44)(H,40,45)(H,41,46)/t28-,30-,31-,32-/m0/s1 GQKWRERWSHSLFH-MCEBTLFFSA-N 50199865 (S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-1-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)pyrrolidine-2-carboxamide::CHEMBL412923 Mu-type opioid receptor Cavia cutleri 0.27 ChEMBL 10.1016/j.bmc.2006.11.019 10.7270/Q2348K1F 17142049 Li, T; Jinsmaa, Y; Nedachi, M; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Bryant, SD; Marczak, E; Li, Q; Swartzwelder, HS; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199865&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11983337 104080345 CHEMBL412923 ZINC28816957 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50366841 Cc1cc(O)cc(C)c1C[C@H](NCC=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC=C InChI=1S/C42H50N6O5/c1-5-18-43-37(25-33-27(3)21-31(49)22-28(33)4)42(53)48-20-12-17-38(48)41(52)47-36(24-30-26-45-34-16-11-10-15-32(30)34)40(51)46-35(39(50)44-19-6-2)23-29-13-8-7-9-14-29/h5-11,13-16,21-22,26,35-38,43,45,49H,1-2,12,17-20,23-25H2,3-4H3,(H,44,50)(H,46,51)(H,47,52)/t35-,36-,37-,38-/m0/s1 ILJAICMRHMTKBM-ZQWQDMLBSA-N 50199859 (S)-N-((S)-1-((S)-1-(allylamino)-1-oxo-3-phenylpropan-2-ylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-1-((S)-2-(allylamino)-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)pyrrolidine-2-carboxamide::CHEMBL397177 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1016/j.bmc.2006.11.019 10.7270/Q2348K1F 17142049 Li, T; Jinsmaa, Y; Nedachi, M; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Bryant, SD; Marczak, E; Li, Q; Swartzwelder, HS; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199859&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44429953 104080339 CHEMBL397177 ZINC28816960 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50366851 CCCN(C(=O)[C@H](Cc1c(C)cc(O)cc1C)NCC=C)c1cnc(N(CCC)C(=O)[C@H](Cc2c(C)cc(O)cc2C)NCC=C)c(=O)[nH]1 InChI=1S/C38H52N6O5/c1-9-13-39-32(21-30-24(5)17-28(45)18-25(30)6)37(48)43(15-11-3)34-23-41-35(36(47)42-34)44(16-12-4)38(49)33(40-14-10-2)22-31-26(7)19-29(46)20-27(31)8/h9-10,17-20,23,32-33,39-40,45-46H,1-2,11-16,21-22H2,3-8H3,(H,42,47)/t32-,33-/m0/s1 NWDZARLHJWJMPM-LQJZCPKCSA-N 50199867 (S)-2-allylamino-N-(5-{[(S)-2-allylamino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-propyl-amino}-3-oxo-3,4-dihydro-pyrazin-2-yl)-3-(4-hydroxy-2,6-dimethyl-phenyl)-N-propyl-propionamide::CHEMBL396506 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1016/j.bmc.2006.11.019 10.7270/Q2348K1F 17142049 Li, T; Jinsmaa, Y; Nedachi, M; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Bryant, SD; Marczak, E; Li, Q; Swartzwelder, HS; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199867&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44429955 104080347 CHEMBL396506 ZINC28816966 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50366856 Cc1cc(O)cc(C)c1C[C@H](NCC=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C39H46N6O5/c1-4-16-41-34(22-30-24(2)18-28(46)19-25(30)3)39(50)45-17-10-15-35(45)38(49)44-33(21-27-23-42-31-14-9-8-13-29(27)31)37(48)43-32(36(40)47)20-26-11-6-5-7-12-26/h4-9,11-14,18-19,23,32-35,41-42,46H,1,10,15-17,20-22H2,2-3H3,(H2,40,47)(H,43,48)(H,44,49)/t32-,33-,34-,35-/m0/s1 NPLKRVKGYGQWKN-BBACVFHCSA-N 50199863 (S)-1-((S)-2-(allylamino)-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)pyrrolidine-2-carboxamide::CHEMBL412924 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1016/j.bmc.2006.11.019 10.7270/Q2348K1F 17142049 Li, T; Jinsmaa, Y; Nedachi, M; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Bryant, SD; Marczak, E; Li, Q; Swartzwelder, HS; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50199863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50199863&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16051448 104080343 CHEMBL412924 ZINC28816962 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50366859 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C32H37N5O5/c33-25(18-23-13-15-24(38)16-14-23)32(42)37-17-7-12-28(37)31(41)36-27(20-22-10-5-2-6-11-22)30(40)35-26(29(34)39)19-21-8-3-1-4-9-21/h1-6,8-11,13-16,25-28,38H,7,12,17-20,33H2,(H2,34,39)(H,35,40)(H,36,41)/t25-,26-,27-,28-/m0/s1 XIJHWXXXIMEHKW-LJWNLINESA-N 50139013 (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::(S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxamide::1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylicacid[1-((S)-(S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL333357::H-Tyr-Pro-Phe-Phe-NH2::Tyr-Pro-Phe-Phe-NH2::endomorphin-2 Mu-type opioid receptor Cavia cutleri 6.88 ChEMBL 10.1016/j.bmc.2006.11.019 10.7270/Q2348K1F 17142049 Li, T; Jinsmaa, Y; Nedachi, M; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Bryant, SD; Marczak, E; Li, Q; Swartzwelder, HS; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139013&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311081 104029000 CHEMBL333357 3668 ZINC14951634 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50373124 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C32H37N5O5/c33-25(18-23-13-15-24(38)16-14-23)32(42)37-17-7-12-28(37)31(41)36-27(20-22-10-5-2-6-11-22)30(40)35-26(29(34)39)19-21-8-3-1-4-9-21/h1-6,8-11,13-16,25-28,38H,7,12,17-20,33H2,(H2,34,39)(H,35,40)(H,36,41)/t25-,26-,27-,28-/m0/s1 XIJHWXXXIMEHKW-LJWNLINESA-N 50139013 (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::(S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxamide::1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylicacid[1-((S)-(S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL333357::H-Tyr-Pro-Phe-Phe-NH2::Tyr-Pro-Phe-Phe-NH2::endomorphin-2 Mu-type opioid receptor Cavia cutleri 7.7 ChEMBL 10.1021/jm060998u 10.7270/Q28915JT 17266203 Fichna, J; do-Rego, JC; Chung, NN; Lemieux, C; Schiller, PW; Poels, J; Broeck, JV; Costentin, J; Janecka, A Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139013&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311081 104029000 CHEMBL333357 3668 ZINC14951634 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50373126 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(N)=O InChI=1S/C38H40N6O5/c39-30(19-23-12-15-28(45)16-13-23)38(49)44-17-5-10-34(44)37(48)43-33(21-27-22-41-31-9-4-3-8-29(27)31)36(47)42-32(35(40)46)20-24-11-14-25-6-1-2-7-26(25)18-24/h1-4,6-9,11-16,18,22,30,32-34,41,45H,5,10,17,19-21,39H2,(H2,40,46)(H,42,47)(H,43,48)/t30-,32+,33-,34-/m0/s1 PXTYYNQYSIYWFW-SSGXOEHOSA-N 50203826 CHEMBL267211::Tyr-Pro-Trp-D-2-Nal-NH2 Mu-type opioid receptor Cavia cutleri 3470 ChEMBL 10.1021/jm060998u 10.7270/Q28915JT 17266203 Fichna, J; do-Rego, JC; Chung, NN; Lemieux, C; Schiller, PW; Poels, J; Broeck, JV; Costentin, J; Janecka, A Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203826 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203826&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16105562 104082784 CHEMBL267211 ZINC49592759 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50373130 Cc1cc(C[C@H](N)C(=O)N2CCC[C@H]2C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@H](Cc2cccc3ccccc23)C(N)=O)cc(C)c1O InChI=1S/C40H44N6O5/c1-23-17-25(18-24(2)36(23)47)19-31(41)40(51)46-16-8-15-35(46)39(50)45-34(21-28-22-43-32-14-6-5-13-30(28)32)38(49)44-33(37(42)48)20-27-11-7-10-26-9-3-4-12-29(26)27/h3-7,9-14,17-18,22,31,33-35,43,47H,8,15-16,19-21,41H2,1-2H3,(H2,42,48)(H,44,49)(H,45,50)/t31-,33+,34-,35-/m0/s1 SFFOEWDACJBOOX-ZFOKTMFVSA-N 50203829 CHEMBL375068::Dmt-Pro-Trp-D-1-Nal-NH2 Mu-type opioid receptor Cavia cutleri 16 ChEMBL 10.1021/jm060998u 10.7270/Q28915JT 17266203 Fichna, J; do-Rego, JC; Chung, NN; Lemieux, C; Schiller, PW; Poels, J; Broeck, JV; Costentin, J; Janecka, A Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203829 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203829&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16105559 104082787 CHEMBL375068 ZINC49776235 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50377726 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccccc1 InChI=1S/C41H47N5O6/c1-27-21-33(47)22-28(2)34(27)24-35(42)40(50)46-25-31-16-10-9-15-30(31)23-37(46)39(49)43-20-12-11-19-36(38(48)44-32-17-7-4-8-18-32)45-41(51)52-26-29-13-5-3-6-14-29/h3-10,13-18,21-22,35-37,47H,11-12,19-20,23-26,42H2,1-2H3,(H,43,49)(H,44,48)(H,45,51)/t35-,36-,37-/m0/s1 LUOIVKZEIDFCGZ-FSEITFBQSA-N 50207190 CHEMBL396423::benzyl (S)-6-((S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido)-1-oxo-1-(phenylamino)hexan-2-ylcarbamate Mu-type opioid receptor Cavia cutleri 711 ChEMBL 10.1016/j.bmc.2007.02.039 10.7270/Q2ST7PHP 17339114 Balboni, G; Onnis, V; Congiu, C; Zotti, M; Sasaki, Y; Ambo, A; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Lazzari, I; Trapella, C; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50207190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50207190&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44431285 104084891 CHEMBL396423 ZINC28821088 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50377728 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCCCC[C@H](N)c1nc2ccccc2[nH]1 InChI=1S/C33H40N6O3/c1-20-15-24(40)16-21(2)25(20)18-27(35)33(42)39-19-23-10-4-3-9-22(23)17-30(39)32(41)36-14-8-7-11-26(34)31-37-28-12-5-6-13-29(28)38-31/h3-6,9-10,12-13,15-16,26-27,30,40H,7-8,11,14,17-19,34-35H2,1-2H3,(H,36,41)(H,37,38)/t26-,27-,30-/m0/s1 YQQMQROTEMPVHU-VWYPKUQYSA-N 50207191 (S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-N-((S)-5-amino-5-(1H-benzo[d]imidazol-2-yl)pentyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::CHEMBL232815 Mu-type opioid receptor Cavia cutleri 434 ChEMBL 10.1016/j.bmc.2007.02.039 10.7270/Q2ST7PHP 17339114 Balboni, G; Onnis, V; Congiu, C; Zotti, M; Sasaki, Y; Ambo, A; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Lazzari, I; Trapella, C; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50207191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50207191&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44431295 104084892 CHEMBL232815 ZINC28821112 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50377732 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCCCC[C@H](NC(=O)OCc1ccccc1)c1nc2ccccc2[nH]1 InChI=1S/C41H46N6O5/c1-26-20-31(48)21-27(2)32(26)23-33(42)40(50)47-24-30-15-7-6-14-29(30)22-37(47)39(49)43-19-11-10-18-36(38-44-34-16-8-9-17-35(34)45-38)46-41(51)52-25-28-12-4-3-5-13-28/h3-9,12-17,20-21,33,36-37,48H,10-11,18-19,22-25,42H2,1-2H3,(H,43,49)(H,44,45)(H,46,51)/t33-,36-,37-/m0/s1 ULBJIWJGABTABW-WOFUPGFCSA-N 50207189 CHEMBL438681::benzyl (S)-5-((S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido)-1-(1H-benzo[d]imidazol-2-yl)pentylcarbamate Mu-type opioid receptor Cavia cutleri 618 ChEMBL 10.1016/j.bmc.2007.02.039 10.7270/Q2ST7PHP 17339114 Balboni, G; Onnis, V; Congiu, C; Zotti, M; Sasaki, Y; Ambo, A; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Lazzari, I; Trapella, C; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50207189 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50207189&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44431288 104084890 CHEMBL438681 ZINC28821094 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50377737 CC(=O)N[C@@H](CCCCNC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)Nc1ccccc1 InChI=1S/C35H43N5O5/c1-22-17-28(42)18-23(2)29(22)20-30(36)35(45)40-21-26-12-8-7-11-25(26)19-32(40)34(44)37-16-10-9-15-31(38-24(3)41)33(43)39-27-13-5-4-6-14-27/h4-8,11-14,17-18,30-32,42H,9-10,15-16,19-21,36H2,1-3H3,(H,37,44)(H,38,41)(H,39,43)/t30-,31-,32-/m0/s1 FXKBVHZYGDBEDB-CPCREDONSA-N 50207196 (S)-N-((S)-5-acetamido-6-oxo-6-(phenylamino)hexyl)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::CHEMBL232514 Mu-type opioid receptor Cavia cutleri 486 ChEMBL 10.1016/j.bmc.2007.02.039 10.7270/Q2ST7PHP 17339114 Balboni, G; Onnis, V; Congiu, C; Zotti, M; Sasaki, Y; Ambo, A; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Lazzari, I; Trapella, C; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50207196 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50207196&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44431286 104084897 CHEMBL232514 ZINC28821089 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50377741 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCCCC[C@H](N)C(=O)Nc1ccccc1 InChI=1S/C33H41N5O4/c1-21-16-26(39)17-22(2)27(21)19-29(35)33(42)38-20-24-11-7-6-10-23(24)18-30(38)32(41)36-15-9-8-14-28(34)31(40)37-25-12-4-3-5-13-25/h3-7,10-13,16-17,28-30,39H,8-9,14-15,18-20,34-35H2,1-2H3,(H,36,41)(H,37,40)/t28-,29-,30-/m0/s1 CPUXPXGRKXPITB-DTXPUJKBSA-N 50207193 (S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-N-((S)-5-amino-6-oxo-6-(phenylamino)hexyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::CHEMBL396424 Mu-type opioid receptor Cavia cutleri 515 ChEMBL 10.1016/j.bmc.2007.02.039 10.7270/Q2ST7PHP 17339114 Balboni, G; Onnis, V; Congiu, C; Zotti, M; Sasaki, Y; Ambo, A; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Lazzari, I; Trapella, C; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50207193 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50207193&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44431287 104084894 CHEMBL396424 ZINC28821092 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50377743 CC(=O)N[C@@H](CCCCNC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)c1nc2ccccc2[nH]1 InChI=1S/C35H42N6O4/c1-21-16-26(43)17-22(2)27(21)19-28(36)35(45)41-20-25-11-5-4-10-24(25)18-32(41)34(44)37-15-9-8-14-31(38-23(3)42)33-39-29-12-6-7-13-30(29)40-33/h4-7,10-13,16-17,28,31-32,43H,8-9,14-15,18-20,36H2,1-3H3,(H,37,44)(H,38,42)(H,39,40)/t28-,31-,32-/m0/s1 MDXGSFQPRAXXFR-MHDHXZMLSA-N 50207195 (S)-N-((S)-5-acetamido-5-(1H-benzo[d]imidazol-2-yl)pentyl)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::CHEMBL397357 Mu-type opioid receptor Cavia cutleri 610 ChEMBL 10.1016/j.bmc.2007.02.039 10.7270/Q2ST7PHP 17339114 Balboni, G; Onnis, V; Congiu, C; Zotti, M; Sasaki, Y; Ambo, A; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Lazzari, I; Trapella, C; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50207195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50207195&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44431289 104084896 CHEMBL397357 ZINC28821098 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50377744 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCCCC[C@H](N)C(=O)NCc1ccccc1 InChI=1S/C34H43N5O4/c1-22-16-27(40)17-23(2)28(22)19-30(36)34(43)39-21-26-13-7-6-12-25(26)18-31(39)33(42)37-15-9-8-14-29(35)32(41)38-20-24-10-4-3-5-11-24/h3-7,10-13,16-17,29-31,40H,8-9,14-15,18-21,35-36H2,1-2H3,(H,37,42)(H,38,41)/t29-,30-,31-/m0/s1 TYWXYNQDKVVPHM-CHQNGUEUSA-N 50207192 (S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-N-((S)-5-amino-6-(benzylamino)-6-oxohexyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::CHEMBL396422 Mu-type opioid receptor Cavia cutleri 553 ChEMBL 10.1016/j.bmc.2007.02.039 10.7270/Q2ST7PHP 17339114 Balboni, G; Onnis, V; Congiu, C; Zotti, M; Sasaki, Y; Ambo, A; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Lazzari, I; Trapella, C; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50207192 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50207192&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44431284 104084893 CHEMBL396422 ZINC28821087 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50377746 CC(=O)N[C@@H](CCCCNC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)NCc1ccccc1 InChI=1S/C36H45N5O5/c1-23-17-29(43)18-24(2)30(23)20-31(37)36(46)41-22-28-14-8-7-13-27(28)19-33(41)35(45)38-16-10-9-15-32(40-25(3)42)34(44)39-21-26-11-5-4-6-12-26/h4-8,11-14,17-18,31-33,43H,9-10,15-16,19-22,37H2,1-3H3,(H,38,45)(H,39,44)(H,40,42)/t31-,32-,33-/m0/s1 WIBJTEFCRARSQT-ZDCRTTOTSA-N 50207188 (S)-N-((S)-5-acetamido-6-(benzylamino)-6-oxohexyl)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::CHEMBL232813 Mu-type opioid receptor Cavia cutleri 1990 ChEMBL 10.1016/j.bmc.2007.02.039 10.7270/Q2ST7PHP 17339114 Balboni, G; Onnis, V; Congiu, C; Zotti, M; Sasaki, Y; Ambo, A; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Lazzari, I; Trapella, C; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50207188 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50207188&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44431281 104084889 CHEMBL232813 ZINC28821077 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50377748 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)NCc1ccccc1 InChI=1S/C42H49N5O6/c1-28-21-34(48)22-29(2)35(28)24-36(43)41(51)47-26-33-18-10-9-17-32(33)23-38(47)40(50)44-20-12-11-19-37(39(49)45-25-30-13-5-3-6-14-30)46-42(52)53-27-31-15-7-4-8-16-31/h3-10,13-18,21-22,36-38,48H,11-12,19-20,23-27,43H2,1-2H3,(H,44,50)(H,45,49)(H,46,52)/t36-,37-,38-/m0/s1 XIWVPWJKWCOGFG-QXUSSCGESA-N 50207194 CHEMBL232812::benzyl (S)-6-((S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido)-1-(benzylamino)-1-oxohexan-2-ylcarbamate Mu-type opioid receptor Cavia cutleri 1451 ChEMBL 10.1016/j.bmc.2007.02.039 10.7270/Q2ST7PHP 17339114 Balboni, G; Onnis, V; Congiu, C; Zotti, M; Sasaki, Y; Ambo, A; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Lazzari, I; Trapella, C; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50207194 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50207194&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16739370 104084895 CHEMBL232812 ZINC28821066 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50370507 CCCC[C@@H](NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](Cc1cc2ccccc2[nH]1)C(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C58H73N11O13/c1-6-7-21-43(64-54(78)47(32-49(72)73)66-53(77)44(28-35-16-10-8-11-17-35)67-57(81)82-58(3,4)5)52(76)65-46(31-39-30-38-20-14-15-22-42(38)62-39)56(80)69-68-55(79)45(29-36-18-12-9-13-19-36)63-48(71)33-60-50(74)34(2)61-51(75)41(59)27-37-23-25-40(70)26-24-37/h8-20,22-26,30,34,41,43-47,62,70H,6-7,21,27-29,31-33,59H2,1-5H3,(H,60,74)(H,61,75)(H,63,71)(H,64,78)(H,65,76)(H,66,77)(H,67,81)(H,68,79)(H,69,80)(H,72,73)/t34-,41+,43-,44-,45+,46+,47-/m1/s1 FEOAQCGOOODCEB-YAMJKISESA-N 50202107 CHEMBL218600::H-Tyr-D-Ala-Gly-Phe-NH-NH-Trp-D-Nle-D-Asp-D-Phe-Boc Mu-type opioid receptor Cavia cutleri 530 ChEMBL 10.1021/jm061268p 10.7270/Q2TD9X17 17201419 Lee, YS; Agnes, RS; Davis, P; Ma, SW; Badghisi, H; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202107&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16100406 104081736 CHEMBL218600 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50370515 CCCC[C@@H](NC(=O)[C@H](Cc1cc2ccccc2[nH]1)NC(=O)OC(C)(C)C)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](Cc1ccccc1)C(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C58H73N11O13/c1-6-7-21-43(64-53(77)46(67-57(81)82-58(3,4)5)31-39-30-38-20-14-15-22-42(38)62-39)52(76)66-47(32-49(72)73)54(78)65-45(29-36-18-12-9-13-19-36)56(80)69-68-55(79)44(28-35-16-10-8-11-17-35)63-48(71)33-60-50(74)34(2)61-51(75)41(59)27-37-23-25-40(70)26-24-37/h8-20,22-26,30,34,41,43-47,62,70H,6-7,21,27-29,31-33,59H2,1-5H3,(H,60,74)(H,61,75)(H,63,71)(H,64,77)(H,65,78)(H,66,76)(H,67,81)(H,68,79)(H,69,80)(H,72,73)/t34-,41+,43-,44+,45-,46+,47-/m1/s1 STEAMACHIRWBBH-LDRAPDDUSA-N 50202111 CHEMBL386186::H-Tyr-D-Ala-Gly-Phe-NH-NH-D-Phe-D-Asp-D-Nle-Trp-Boc Mu-type opioid receptor Cavia cutleri 210 ChEMBL 10.1021/jm061268p 10.7270/Q2TD9X17 17201419 Lee, YS; Agnes, RS; Davis, P; Ma, SW; Badghisi, H; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202111 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202111&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16100408 104081740 CHEMBL386186 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50370524 CCCC[C@@H](NC(=O)[C@@H](N)Cc1cc2ccccc2[nH]1)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](Cc1ccccc1)C(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C53H65N11O11/c1-3-4-18-41(60-49(71)39(55)28-36-27-35-17-11-12-19-40(35)58-36)50(72)62-44(29-46(67)68)51(73)61-43(26-33-15-9-6-10-16-33)53(75)64-63-52(74)42(25-32-13-7-5-8-14-32)59-45(66)30-56-47(69)31(2)57-48(70)38(54)24-34-20-22-37(65)23-21-34/h5-17,19-23,27,31,38-39,41-44,58,65H,3-4,18,24-26,28-30,54-55H2,1-2H3,(H,56,69)(H,57,70)(H,59,66)(H,60,71)(H,61,73)(H,62,72)(H,63,74)(H,64,75)(H,67,68)/t31-,38+,39+,41-,42+,43-,44-/m1/s1 NXHWDEQNHXTHJU-KDWYPSCJSA-N 50202109 CHEMBL375359::H-Tyr-D-Ala-Gly-Phe-NH-NH-D-Phe-D-Asp-D-Nle-Trp-H Mu-type opioid receptor Cavia cutleri 97 ChEMBL 10.1021/jm061268p 10.7270/Q2TD9X17 17201419 Lee, YS; Agnes, RS; Davis, P; Ma, SW; Badghisi, H; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202109 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202109&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16100411 104081738 CHEMBL375359 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50370529 CCCC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@H](Cc1cc2ccccc2[nH]1)C(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C53H65N11O11/c1-3-4-18-41(60-51(73)44(29-46(67)68)61-49(71)39(55)24-32-13-7-5-8-14-32)50(72)62-43(28-36-27-35-17-11-12-19-40(35)58-36)53(75)64-63-52(74)42(26-33-15-9-6-10-16-33)59-45(66)30-56-47(69)31(2)57-48(70)38(54)25-34-20-22-37(65)23-21-34/h5-17,19-23,27,31,38-39,41-44,58,65H,3-4,18,24-26,28-30,54-55H2,1-2H3,(H,56,69)(H,57,70)(H,59,66)(H,60,73)(H,61,71)(H,62,72)(H,63,74)(H,64,75)(H,67,68)/t31-,38+,39+,41+,42+,43-,44+/m1/s1 KYWMQIRORZGHDH-QOIWPSRPSA-N 50202114 CHEMBL386212::H-Tyr-D-Ala-Gly-Phe-NH-NH-D-Trp-Nle-Asp-Phe-H Mu-type opioid receptor Cavia cutleri 93 ChEMBL 10.1021/jm061268p 10.7270/Q2TD9X17 17201419 Lee, YS; Agnes, RS; Davis, P; Ma, SW; Badghisi, H; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202114 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202114&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16100410 104081743 CHEMBL386212 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50370533 CCCC[C@@H](NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](N)Cc1ccccc1)C(=O)N[C@@H](Cc1cc2ccccc2[nH]1)C(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C53H65N11O11/c1-3-4-18-41(60-51(73)44(29-46(67)68)61-49(71)39(55)24-32-13-7-5-8-14-32)50(72)62-43(28-36-27-35-17-11-12-19-40(35)58-36)53(75)64-63-52(74)42(26-33-15-9-6-10-16-33)59-45(66)30-56-47(69)31(2)57-48(70)38(54)25-34-20-22-37(65)23-21-34/h5-17,19-23,27,31,38-39,41-44,58,65H,3-4,18,24-26,28-30,54-55H2,1-2H3,(H,56,69)(H,57,70)(H,59,66)(H,60,73)(H,61,71)(H,62,72)(H,63,74)(H,64,75)(H,67,68)/t31-,38+,39-,41-,42+,43+,44-/m1/s1 KYWMQIRORZGHDH-KKSWQRHZSA-N 50202110 CHEMBL218651::H-Tyr-D-Ala-Gly-Phe-NH-NH-Trp-D-Nle-D-Asp-D-Phe-H Mu-type opioid receptor Cavia cutleri 76 ChEMBL 10.1021/jm061268p 10.7270/Q2TD9X17 17201419 Lee, YS; Agnes, RS; Davis, P; Ma, SW; Badghisi, H; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202110 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202110&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16100409 104081739 CHEMBL218651 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50369579 COc1ccc(C[C@H](N=C(N)N)C(=O)N2CCC[C@@H]2C(=O)NCC(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)cc1 InChI=1S/C38H45N9O6/c1-53-26-15-13-24(14-16-26)19-31(46-38(40)41)37(52)47-17-7-12-32(47)36(51)43-22-33(48)44-30(20-25-21-42-28-11-6-5-10-27(25)28)35(50)45-29(34(39)49)18-23-8-3-2-4-9-23/h2-6,8-11,13-16,21,29-32,42H,7,12,17-20,22H2,1H3,(H2,39,49)(H,43,51)(H,44,48)(H,45,50)(H4,40,41,46)/t29-,30-,31-,32+/m0/s1 OEGSFHSEWVWDGF-RTNMLALUSA-N 50201411 CHEMBL243724::N alpha-amidino-Tyr(Me)-D-Pro-Gly-Trp-Phe-NH2 Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1016/j.bmc.2006.12.007 10.7270/Q2W958V6 17188879 Liu, H; Zhang, B; Liu, X; Wang, C; Ni, J; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50201411 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50201411&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44428306 104081280 CHEMBL243724 ZINC28712993 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50370545 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C46H56N10O10/c1-27(51-43(63)35(47)21-31-13-17-33(57)18-14-31)41(61)49-25-39(59)53-37(23-29-9-5-3-6-10-29)45(65)55-56-46(66)38(24-30-11-7-4-8-12-30)54-40(60)26-50-42(62)28(2)52-44(64)36(48)22-32-15-19-34(58)20-16-32/h3-20,27-28,35-38,57-58H,21-26,47-48H2,1-2H3,(H,49,61)(H,50,62)(H,51,63)(H,52,64)(H,53,59)(H,54,60)(H,55,65)(H,56,66)/t27-,28-,35+,36+,37+,38+/m1/s1 DESSEGDLRYOPTJ-VRANXALZSA-N 21014 (2S)-2-amino-N-[(1R)-1-[({[(1S)-1-{N'-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanoyl]hydrazinecarbonyl}-2-phenylethyl]carbamoyl}methyl)carbamoyl]ethyl]-3-(4-hydroxyphenyl)propanamide::(Tyr-Ala-Gly-Phe-NH2)2::Biphalin::CHEMBL200199::bis(Tyr-Ala-Gly-PheNH2)hydrazide::enkephalin dimer Mu-type opioid receptor Cavia cutleri 8.8 ChEMBL 10.1021/jm061268p 10.7270/Q2TD9X17 17201419 Lee, YS; Agnes, RS; Davis, P; Ma, SW; Badghisi, H; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21014&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5487663 49689087 CHEMBL200199 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50370561 CCCC[C@H](NC(=O)[C@H](N)Cc1cc2ccccc2[nH]1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C53H65N11O11/c1-3-4-18-41(60-49(71)39(55)28-36-27-35-17-11-12-19-40(35)58-36)50(72)62-44(29-46(67)68)51(73)61-43(26-33-15-9-6-10-16-33)53(75)64-63-52(74)42(25-32-13-7-5-8-14-32)59-45(66)30-56-47(69)31(2)57-48(70)38(54)24-34-20-22-37(65)23-21-34/h5-17,19-23,27,31,38-39,41-44,58,65H,3-4,18,24-26,28-30,54-55H2,1-2H3,(H,56,69)(H,57,70)(H,59,66)(H,60,71)(H,61,73)(H,62,72)(H,63,74)(H,64,75)(H,67,68)/t31-,38+,39-,41+,42+,43+,44+/m1/s1 NXHWDEQNHXTHJU-AYMWOJQISA-N 50202112 (3S)-3-[(2S)-2-[(2R)-2-amino-3-(1H-indol-2-yl)propanamido]hexanamido]-3-{[(2S)-1-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanehydrazido]-1-oxo-3-phenylpropan-2-yl]carbamoyl}propanoic acid::CHEMBL407198 Mu-type opioid receptor Cavia cutleri 81 ChEMBL 10.1021/jm061268p 10.7270/Q2TD9X17 17201419 Lee, YS; Agnes, RS; Davis, P; Ma, SW; Badghisi, H; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202112 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202112&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44418924 104081741 CHEMBL407198 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50370563 CCCC[C@H](NC(=O)[C@@H](Cc1cc2ccccc2[nH]1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C58H73N11O13/c1-6-7-21-43(64-53(77)46(67-57(81)82-58(3,4)5)31-39-30-38-20-14-15-22-42(38)62-39)52(76)66-47(32-49(72)73)54(78)65-45(29-36-18-12-9-13-19-36)56(80)69-68-55(79)44(28-35-16-10-8-11-17-35)63-48(71)33-60-50(74)34(2)61-51(75)41(59)27-37-23-25-40(70)26-24-37/h8-20,22-26,30,34,41,43-47,62,70H,6-7,21,27-29,31-33,59H2,1-5H3,(H,60,74)(H,61,75)(H,63,71)(H,64,77)(H,65,78)(H,66,76)(H,67,81)(H,68,79)(H,69,80)(H,72,73)/t34-,41+,43+,44+,45+,46-,47+/m1/s1 STEAMACHIRWBBH-RXFVQNAMSA-N 50202108 (3S)-3-{[(2S)-1-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanehydrazido]-1-oxo-3-phenylpropan-2-yl]carbamoyl}-3-[(2S)-2-[(2R)-2-{[(tert-butoxy)carbonyl]amino}-3-(1H-indol-2-yl)propanamido]hexanamido]propanoic acid::CHEMBL414087 Mu-type opioid receptor Cavia cutleri 460 ChEMBL 10.1021/jm061268p 10.7270/Q2TD9X17 17201419 Lee, YS; Agnes, RS; Davis, P; Ma, SW; Badghisi, H; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202108 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202108&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44418923 104081737 CHEMBL414087 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50370574 CCCC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(=O)N[C@H](Cc1cc2ccccc2[nH]1)C(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C58H73N11O13/c1-6-7-21-43(64-54(78)47(32-49(72)73)66-53(77)44(28-35-16-10-8-11-17-35)67-57(81)82-58(3,4)5)52(76)65-46(31-39-30-38-20-14-15-22-42(38)62-39)56(80)69-68-55(79)45(29-36-18-12-9-13-19-36)63-48(71)33-60-50(74)34(2)61-51(75)41(59)27-37-23-25-40(70)26-24-37/h8-20,22-26,30,34,41,43-47,62,70H,6-7,21,27-29,31-33,59H2,1-5H3,(H,60,74)(H,61,75)(H,63,71)(H,64,78)(H,65,76)(H,66,77)(H,67,81)(H,68,79)(H,69,80)(H,72,73)/t34-,41+,43+,44+,45+,46-,47+/m1/s1 FEOAQCGOOODCEB-RXFVQNAMSA-N 50202115 CHEMBL217957::H-Tyr-D-Ala-Gly-Phe-NH-NH-D-Trp-Nle-Asp-Phe-Bo Mu-type opioid receptor Cavia cutleri 240 ChEMBL 10.1021/jm061268p 10.7270/Q2TD9X17 17201419 Lee, YS; Agnes, RS; Davis, P; Ma, SW; Badghisi, H; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202115 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202115&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16100407 104081744 CHEMBL217957 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50369587 COc1ccc(C[C@H](N=C(N)N)C(=O)N2CCC[C@H]2C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)cc1 InChI=1S/C36H42N8O5/c1-49-25-15-13-23(14-16-25)19-30(43-36(38)39)35(48)44-17-7-12-31(44)34(47)42-29(20-24-21-40-27-11-6-5-10-26(24)27)33(46)41-28(32(37)45)18-22-8-3-2-4-9-22/h2-6,8-11,13-16,21,28-31,40H,7,12,17-20H2,1H3,(H2,37,45)(H,41,46)(H,42,47)(H4,38,39,43)/t28-,29-,30-,31-/m0/s1 QKBVJESURFKHSK-ORYMTKCHSA-N 50201414 CHEMBL390271::N alpha-amidino-Tyr(Me)-Pro-Trp-Phe-NH2 Mu-type opioid receptor Cavia cutleri 988 ChEMBL 10.1016/j.bmc.2006.12.007 10.7270/Q2W958V6 17188879 Liu, H; Zhang, B; Liu, X; Wang, C; Ni, J; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50201414 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50201414&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44428305 104081283 CHEMBL390271 ZINC28712991 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50369589 COc1ccc(C[C@H](N=C(N)N)C(=O)N2CCC[C@@H]2C(=O)NCC(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](Cc2ccc(Cl)cc2)C(N)=O)cc1 InChI=1S/C38H44ClN9O6/c1-54-26-14-10-23(11-15-26)18-31(47-38(41)42)37(53)48-16-4-7-32(48)36(52)44-21-33(49)45-30(19-24-20-43-28-6-3-2-5-27(24)28)35(51)46-29(34(40)50)17-22-8-12-25(39)13-9-22/h2-3,5-6,8-15,20,29-32,43H,4,7,16-19,21H2,1H3,(H2,40,50)(H,44,52)(H,45,49)(H,46,51)(H4,41,42,47)/t29-,30-,31-,32+/m0/s1 GDPQVNYUWUCSIG-RTNMLALUSA-N 50201413 CHEMBL390689::N alpha-amidino-Tyr(Me)-D-Pro-Gly-Trp-p-Cl-Phe-NH2 Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1016/j.bmc.2006.12.007 10.7270/Q2W958V6 17188879 Liu, H; Zhang, B; Liu, X; Wang, C; Ni, J; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50201413 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50201413&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16721068 104081282 CHEMBL390689 ZINC95612978 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50369594 COc1ccc(C[C@H](N=C(N)N)C(=O)N2CCC[C@H]2C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](Cc2ccc(Cl)cc2)C(N)=O)cc1 InChI=1S/C36H41ClN8O5/c1-50-25-14-10-22(11-15-25)18-30(44-36(39)40)35(49)45-16-4-7-31(45)34(48)43-29(19-23-20-41-27-6-3-2-5-26(23)27)33(47)42-28(32(38)46)17-21-8-12-24(37)13-9-21/h2-3,5-6,8-15,20,28-31,41H,4,7,16-19H2,1H3,(H2,38,46)(H,42,47)(H,43,48)(H4,39,40,44)/t28-,29-,30-,31-/m0/s1 IEBSBPORJZXBGY-ORYMTKCHSA-N 50201412 CHEMBL243189::N alpha-amidino-Tyr(Me)-Pro-Trp-p-Cl-Phe-NH2 Mu-type opioid receptor Cavia cutleri 845 ChEMBL 10.1016/j.bmc.2006.12.007 10.7270/Q2W958V6 17188879 Liu, H; Zhang, B; Liu, X; Wang, C; Ni, J; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50201412 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50201412&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44428304 104081281 CHEMBL243189 ZINC28712990 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50385925 Cc1ccccc1C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C35H43N5O5/c1-21-10-7-8-13-25(21)19-30(33(43)38-29(32(37)42)18-24-11-5-4-6-12-24)39-34(44)31-14-9-15-40(31)35(45)28(36)20-27-22(2)16-26(41)17-23(27)3/h4-8,10-13,16-17,28-31,41H,9,14-15,18-20,36H2,1-3H3,(H2,37,42)(H,38,43)(H,39,44)/t28-,29-,30-,31-/m0/s1 ILQNJTWDEDHFTC-ORYMTKCHSA-N 50212608 CHEMBL389948::Dmt-Pro-Mmp-Phe-NH2 Mu-type opioid receptor Cavia cutleri 0.16 ChEMBL 10.1021/jm061238m 10.7270/Q25B0264 17497839 Li, T; Shiotani, K; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212608 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212608&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16737287 104088427 CHEMBL389948 ZINC28654439 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50385933 Cc1cc(C)c(C[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)c(C)c1 InChI=1S/C35H43N5O5/c1-21-16-22(2)27(23(3)17-21)20-30(33(43)38-29(32(37)42)19-24-8-5-4-6-9-24)39-34(44)31-10-7-15-40(31)35(45)28(36)18-25-11-13-26(41)14-12-25/h4-6,8-9,11-14,16-17,28-31,41H,7,10,15,18-20,36H2,1-3H3,(H2,37,42)(H,38,43)(H,39,44)/t28-,29-,30-,31-/m0/s1 KFLSQRYJYCLKBS-ORYMTKCHSA-N 50212610 CHEMBL389023::Tyr-Pro-Tmp-Phe-NH Mu-type opioid receptor Cavia cutleri 1.9 ChEMBL 10.1021/jm061238m 10.7270/Q25B0264 17497839 Li, T; Shiotani, K; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212610 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212610&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16736706 104088429 CHEMBL389023 ZINC28654470 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50385941 CC(C)c1cccc(C)c1C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C36H45N5O5/c1-22(2)27-12-7-9-23(3)28(27)21-31(34(44)39-30(33(38)43)20-24-10-5-4-6-11-24)40-35(45)32-13-8-18-41(32)36(46)29(37)19-25-14-16-26(42)17-15-25/h4-7,9-12,14-17,22,29-32,42H,8,13,18-21,37H2,1-3H3,(H2,38,43)(H,39,44)(H,40,45)/t29-,30-,31-,32-/m0/s1 ZMMDWGMVKHLYTG-YDPTYEFTSA-N 50212614 CHEMBL434559::Tyr-Pro-Imp-Phe-NH2 Mu-type opioid receptor Cavia cutleri 2.74 ChEMBL 10.1021/jm061238m 10.7270/Q25B0264 17497839 Li, T; Shiotani, K; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212614 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212614&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16736710 104088433 CHEMBL434559 ZINC28654503 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50385943 Cc1cccc(C)c1C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C34H41N5O5/c1-21-8-6-9-22(2)26(21)20-29(32(42)37-28(31(36)41)19-23-10-4-3-5-11-23)38-33(43)30-12-7-17-39(30)34(44)27(35)18-24-13-15-25(40)16-14-24/h3-6,8-11,13-16,27-30,40H,7,12,17-20,35H2,1-2H3,(H2,36,41)(H,37,42)(H,38,43)/t27-,28-,29-,30-/m0/s1 HJYUYBYISGYHKS-KRCBVYEFSA-N 50212613 CHEMBL266122::Tyr-Pro-Dmp-Phe-NH2 Mu-type opioid receptor Cavia cutleri 0.38 ChEMBL 10.1021/jm061238m 10.7270/Q25B0264 17497839 Li, T; Shiotani, K; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212613 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212613&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10371367 104088432 CHEMBL266122 ZINC28654452 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50385946 CCc1cccc(C)c1C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C37H47N5O5/c1-5-26-14-9-11-22(2)29(26)21-32(35(45)40-31(34(39)44)19-25-12-7-6-8-13-25)41-36(46)33-15-10-16-42(33)37(47)30(38)20-28-23(3)17-27(43)18-24(28)4/h6-9,11-14,17-18,30-33,43H,5,10,15-16,19-21,38H2,1-4H3,(H2,39,44)(H,40,45)(H,41,46)/t30-,31-,32-,33-/m0/s1 FZEQHIVEBCRYJC-YRCZKMHPSA-N 50212617 CHEMBL374818::Dmt-Pro-Emp-Phe-NH2 Mu-type opioid receptor Cavia cutleri 0.17 ChEMBL 10.1021/jm061238m 10.7270/Q25B0264 17497839 Li, T; Shiotani, K; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212617&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16736880 104088436 CHEMBL374818 ZINC28654498 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50385951 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C34H41N5O5/c1-21-16-25(40)17-22(2)26(21)20-27(35)34(44)39-15-9-14-30(39)33(43)38-29(19-24-12-7-4-8-13-24)32(42)37-28(31(36)41)18-23-10-5-3-6-11-23/h3-8,10-13,16-17,27-30,40H,9,14-15,18-20,35H2,1-2H3,(H2,36,41)(H,37,42)(H,38,43)/t27-,28-,29-,30-/m0/s1 PJAMNQXPYIKTPE-KRCBVYEFSA-N 50149384 (S)-1-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL331325::Dmt-Pro-Phe-Phe-NH2 Mu-type opioid receptor Cavia cutleri 0.26 ChEMBL 10.1021/jm061238m 10.7270/Q25B0264 17497839 Li, T; Shiotani, K; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149384 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149384&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10077295 104037529 CHEMBL331325 ZINC27184002 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50385952 Cc1cc(C)cc(C[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)c1 InChI=1S/C34H41N5O5/c1-21-15-22(2)17-25(16-21)20-29(32(42)37-28(31(36)41)19-23-7-4-3-5-8-23)38-33(43)30-9-6-14-39(30)34(44)27(35)18-24-10-12-26(40)13-11-24/h3-5,7-8,10-13,15-17,27-30,40H,6,9,14,18-20,35H2,1-2H3,(H2,36,41)(H,37,42)(H,38,43)/t27-,28-,29-,30-/m0/s1 WGUOAUNVYIRMQJ-KRCBVYEFSA-N 50212611 CHEMBL413892::Tyr-Pro-3,5Dmp-Phe-NH2 Mu-type opioid receptor Cavia cutleri 389 ChEMBL 10.1021/jm061238m 10.7270/Q25B0264 17497839 Li, T; Shiotani, K; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212611 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212611&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16736272 104088430 CHEMBL413892 ZINC28654443 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50385953 Cc1cccc(C)c1C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C36H45N5O5/c1-21-10-8-11-22(2)28(21)20-31(34(44)39-30(33(38)43)18-25-12-6-5-7-13-25)40-35(45)32-14-9-15-41(32)36(46)29(37)19-27-23(3)16-26(42)17-24(27)4/h5-8,10-13,16-17,29-32,42H,9,14-15,18-20,37H2,1-4H3,(H2,38,43)(H,39,44)(H,40,45)/t29-,30-,31-,32-/m0/s1 KIPQYPCUMMQKJB-YDPTYEFTSA-N 50212609 CHEMBL228409::Dmt-Pro-Dmp-Phe-NH2 Mu-type opioid receptor Cavia cutleri 0.12 ChEMBL 10.1021/jm061238m 10.7270/Q25B0264 17497839 Li, T; Shiotani, K; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212609 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212609&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16736727 104088428 CHEMBL228409 ZINC28654456 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50385957 Cc1ccccc1C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C33H39N5O5/c1-21-8-5-6-11-24(21)20-28(31(41)36-27(30(35)40)19-22-9-3-2-4-10-22)37-32(42)29-12-7-17-38(29)33(43)26(34)18-23-13-15-25(39)16-14-23/h2-6,8-11,13-16,26-29,39H,7,12,17-20,34H2,1H3,(H2,35,40)(H,36,41)(H,37,42)/t26-,27-,28-,29-/m0/s1 LJUZIHDRCVUPHL-DZUOILHNSA-N 50212620 CHEMBL413676::Tyr-Pro-Mmp-Phe-NH Mu-type opioid receptor Cavia cutleri 1.33 ChEMBL 10.1021/jm061238m 10.7270/Q25B0264 17497839 Li, T; Shiotani, K; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212620 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212620&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16736675 104088439 CHEMBL413676 ZINC28654435 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50385962 CCc1cccc(C)c1C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C35H43N5O5/c1-3-25-12-7-9-22(2)27(25)21-30(33(43)38-29(32(37)42)20-23-10-5-4-6-11-23)39-34(44)31-13-8-18-40(31)35(45)28(36)19-24-14-16-26(41)17-15-24/h4-7,9-12,14-17,28-31,41H,3,8,13,18-21,36H2,1-2H3,(H2,37,42)(H,38,43)(H,39,44)/t28-,29-,30-,31-/m0/s1 AAXFHBRSEVMRCW-ORYMTKCHSA-N 50212615 CHEMBL375274::Tyr-Pro-Emp-Phe-NH2 Mu-type opioid receptor Cavia cutleri 2.35 ChEMBL 10.1021/jm061238m 10.7270/Q25B0264 17497839 Li, T; Shiotani, K; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212615 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212615&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16736708 104088434 CHEMBL375274 ZINC28654493 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50385965 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C32H37N5O5/c33-25(18-23-13-15-24(38)16-14-23)32(42)37-17-7-12-28(37)31(41)36-27(20-22-10-5-2-6-11-22)30(40)35-26(29(34)39)19-21-8-3-1-4-9-21/h1-6,8-11,13-16,25-28,38H,7,12,17-20,33H2,(H2,34,39)(H,35,40)(H,36,41)/t25-,26-,27-,28-/m0/s1 XIJHWXXXIMEHKW-LJWNLINESA-N 50139013 (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::(S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxamide::1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylicacid[1-((S)-(S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL333357::H-Tyr-Pro-Phe-Phe-NH2::Tyr-Pro-Phe-Phe-NH2::endomorphin-2 Mu-type opioid receptor Cavia cutleri 6.9 ChEMBL 10.1021/jm061238m 10.7270/Q25B0264 17497839 Li, T; Shiotani, K; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139013&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311081 104029000 CHEMBL333357 3668 ZINC14951634 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50385967 Cc1cc(O)ccc1C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C33H39N5O6/c1-20-16-25(40)14-11-23(20)19-28(31(42)36-27(30(35)41)18-21-6-3-2-4-7-21)37-32(43)29-8-5-15-38(29)33(44)26(34)17-22-9-12-24(39)13-10-22/h2-4,6-7,9-14,16,26-29,39-40H,5,8,15,17-19,34H2,1H3,(H2,35,41)(H,36,42)(H,37,43)/t26-,27-,28-,29-/m0/s1 NGVFBRDVYVEPFY-DZUOILHNSA-N 50212612 CHEMBL228512::Tyr-Pro-Dmt-Phe-NH2 Mu-type opioid receptor Cavia cutleri 541 ChEMBL 10.1021/jm061238m 10.7270/Q25B0264 17497839 Li, T; Shiotani, K; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212612 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212612&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44424809 104088431 CHEMBL228512 ZINC28654462 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50385973 Cc1cc(C)cc(C[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)c1 InChI=1S/C36H45N5O5/c1-21-13-22(2)15-26(14-21)19-31(34(44)39-30(33(38)43)18-25-9-6-5-7-10-25)40-35(45)32-11-8-12-41(32)36(46)29(37)20-28-23(3)16-27(42)17-24(28)4/h5-7,9-10,13-17,29-32,42H,8,11-12,18-20,37H2,1-4H3,(H2,38,43)(H,39,44)(H,40,45)/t29-,30-,31-,32-/m0/s1 GBRVPIBAPYVZMY-YDPTYEFTSA-N 50212616 CHEMBL389949::Dmt-Pro-3,5Dmp-Phe-NH2 Mu-type opioid receptor Cavia cutleri 14.4 ChEMBL 10.1021/jm061238m 10.7270/Q25B0264 17497839 Li, T; Shiotani, K; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212616 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212616&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16736676 104088435 CHEMBL389949 ZINC28654448 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50385976 Cc1cc(C)c(C[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)c(C)c1 InChI=1S/C37H47N5O5/c1-21-14-22(2)29(23(3)15-21)20-32(35(45)40-31(34(39)44)18-26-10-7-6-8-11-26)41-36(46)33-12-9-13-42(33)37(47)30(38)19-28-24(4)16-27(43)17-25(28)5/h6-8,10-11,14-17,30-33,43H,9,12-13,18-20,38H2,1-5H3,(H2,39,44)(H,40,45)(H,41,46)/t30-,31-,32-,33-/m0/s1 NHSNBLRALWOIIA-YRCZKMHPSA-N 50212621 CHEMBL228503::Dmt-Pro-Tmp-Phe-NH2 Mu-type opioid receptor Cavia cutleri 0.21 ChEMBL 10.1021/jm061238m 10.7270/Q25B0264 17497839 Li, T; Shiotani, K; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212621 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212621&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16737135 104088440 CHEMBL228503 ZINC28654489 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50385980 Cc1cc(O)ccc1C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C35H43N5O6/c1-20-14-25(41)12-11-24(20)18-30(33(44)38-29(32(37)43)17-23-8-5-4-6-9-23)39-34(45)31-10-7-13-40(31)35(46)28(36)19-27-21(2)15-26(42)16-22(27)3/h4-6,8-9,11-12,14-16,28-31,41-42H,7,10,13,17-19,36H2,1-3H3,(H2,37,43)(H,38,44)(H,39,45)/t28-,29-,30-,31-/m0/s1 VSPCTLNQMKBUFW-ORYMTKCHSA-N 50212619 CHEMBL388800::Dmt-Pro-Dmt-Phe-NH2 Mu-type opioid receptor Cavia cutleri 1.94 ChEMBL 10.1021/jm061238m 10.7270/Q25B0264 17497839 Li, T; Shiotani, K; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212619 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212619&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44424810 104088438 CHEMBL388800 ZINC28654466 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50385982 CC(C)c1cccc(C)c1C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C38H49N5O5/c1-22(2)28-14-9-11-23(3)30(28)21-33(36(46)41-32(35(40)45)19-26-12-7-6-8-13-26)42-37(47)34-15-10-16-43(34)38(48)31(39)20-29-24(4)17-27(44)18-25(29)5/h6-9,11-14,17-18,22,31-34,44H,10,15-16,19-21,39H2,1-5H3,(H2,40,45)(H,41,46)(H,42,47)/t31-,32-,33-,34-/m0/s1 PUIMPGYMFMJIOK-CUPIEXAXSA-N 50212618 CHEMBL228516::Dmt-Pro-Imp-Phe-NH2 Mu-type opioid receptor Cavia cutleri 0.2 ChEMBL 10.1021/jm061238m 10.7270/Q25B0264 17497839 Li, T; Shiotani, K; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Jinsmaa, Y; Marczak, E; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212618 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212618&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16737137 104088437 CHEMBL228516 ZINC28654522 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50408287 Cl.CN([C@H]1C[C@@]23CCN(CC4CC4)[C@H]4CC[C@@H]1C[C@@]24Cc1ccc(O)cc31)C(=O)c1ccccc1 InChI=1S/C30H36N2O2.ClH/c1-31(28(34)21-5-3-2-4-6-21)26-18-29-13-14-32(19-20-7-8-20)27-12-10-23(26)17-30(27,29)16-22-9-11-24(33)15-25(22)29;/h2-6,9,11,15,20,23,26-27,33H,7-8,10,12-14,16-19H2,1H3;1H/t23-,26+,27+,29-,30-;/m1./s1 YSMZPJJULQBQCD-VFTKGZTKSA-N 50118186 CHEMBL3613282 Mu-type opioid receptor Cavia cutleri 56 ChEMBL 10.1016/j.bmc.2015.08.036 10.7270/Q2V126M1 26346669 Nakajima, R; Yamamoto, N; Hirayama, S; Iwai, T; Saitoh, A; Nagumo, Y; Fujii, H; Nagase, H University of Tsukuba http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118186 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118186&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44352706 104011523 CHEMBL3613282 ZINC27323787 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50408288 Cl.CN([C@H]1C[C@@]23CCN(CC4CC4)[C@H]4CC[C@@H]1C[C@@]24Cc1ccc(O)cc31)C(=O)Cc1ccccc1 InChI=1S/C31H38N2O2.ClH/c1-32(29(35)15-21-5-3-2-4-6-21)27-19-30-13-14-33(20-22-7-8-22)28-12-10-24(27)18-31(28,30)17-23-9-11-25(34)16-26(23)30;/h2-6,9,11,16,22,24,27-28,34H,7-8,10,12-15,17-20H2,1H3;1H/t24-,27+,28+,30-,31-;/m1./s1 KHCZTDWYSGVKSZ-VWNIWGECSA-N 50118187 CHEMBL3613281 Mu-type opioid receptor Cavia cutleri 60 ChEMBL 10.1016/j.bmc.2015.08.036 10.7270/Q2V126M1 26346669 Nakajima, R; Yamamoto, N; Hirayama, S; Iwai, T; Saitoh, A; Nagumo, Y; Fujii, H; Nagase, H University of Tsukuba http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118187 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118187&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44352574 104011524 CHEMBL3613281 ZINC27313355 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50408289 Cl.CN([C@H]1C[C@@]23CCN(CC4CC4)[C@H]4CC[C@@H]1C[C@@]24Cc1ccc(O)cc31)C(=O)CCc1ccccc1 InChI=1S/C32H40N2O2.ClH/c1-33(30(36)14-9-22-5-3-2-4-6-22)28-20-31-15-16-34(21-23-7-8-23)29-13-11-25(28)19-32(29,31)18-24-10-12-26(35)17-27(24)31;/h2-6,10,12,17,23,25,28-29,35H,7-9,11,13-16,18-21H2,1H3;1H/t25-,28+,29+,31-,32-;/m1./s1 LNQRQQNRENNENZ-WWOYOULDSA-N 50118188 CHEMBL3613280 Mu-type opioid receptor Cavia cutleri 12 ChEMBL 10.1016/j.bmc.2015.08.036 10.7270/Q2V126M1 26346669 Nakajima, R; Yamamoto, N; Hirayama, S; Iwai, T; Saitoh, A; Nagumo, Y; Fujii, H; Nagase, H University of Tsukuba http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118188 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118188&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44352676 104011525 CHEMBL3613280 ZINC27312843 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50408290 Cl.CN([C@H]1C[C@@]23CCN(CC4CC4)[C@H]4CC[C@@H]1C[C@@]24Cc1ccc(O)cc31)C(=O)\C=C\c1ccoc1 InChI=1S/C30H36N2O3.ClH/c1-31(28(34)9-4-21-10-13-35-19-21)26-17-29-11-12-32(18-20-2-3-20)27-8-6-23(26)16-30(27,29)15-22-5-7-24(33)14-25(22)29;/h4-5,7,9-10,13-14,19-20,23,26-27,33H,2-3,6,8,11-12,15-18H2,1H3;1H/b9-4+;/t23-,26+,27+,29-,30-;/m1./s1 JXWCMWQRMRFPLA-RWIWYQPJSA-N 50118189 CHEMBL3613175 Mu-type opioid receptor Cavia cutleri 48 ChEMBL 10.1016/j.bmc.2015.08.036 10.7270/Q2V126M1 26346669 Nakajima, R; Yamamoto, N; Hirayama, S; Iwai, T; Saitoh, A; Nagumo, Y; Fujii, H; Nagase, H University of Tsukuba http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118189 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118189&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44352689 104011526 CHEMBL3613175 ZINC27318214 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50408291 Cl.CN([C@@H]1C[C@@]23CCN(CC4CC4)[C@H]4CC[C@@H]1C[C@@]24Cc1ccc(O)cc31)C(=O)c1ccccc1 InChI=1S/C30H36N2O2.ClH/c1-31(28(34)21-5-3-2-4-6-21)26-18-29-13-14-32(19-20-7-8-20)27-12-10-23(26)17-30(27,29)16-22-9-11-24(33)15-25(22)29;/h2-6,9,11,15,20,23,26-27,33H,7-8,10,12-14,16-19H2,1H3;1H/t23-,26-,27+,29-,30-;/m1./s1 YSMZPJJULQBQCD-PXUSUCDHSA-N 50118190 CHEMBL3613174 Mu-type opioid receptor Cavia cutleri 0.280000 ChEMBL 10.1016/j.bmc.2015.08.036 10.7270/Q2V126M1 26346669 Nakajima, R; Yamamoto, N; Hirayama, S; Iwai, T; Saitoh, A; Nagumo, Y; Fujii, H; Nagase, H University of Tsukuba http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118190&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44352661 104011527 CHEMBL3613174 ZINC27311532 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50408292 Cl.CN([C@@H]1C[C@@]23CCN(CC4CC4)[C@H]4CC[C@@H]1C[C@@]24Cc1ccc(O)cc31)C(=O)Cc1ccccc1 InChI=1S/C31H38N2O2.ClH/c1-32(29(35)15-21-5-3-2-4-6-21)27-19-30-13-14-33(20-22-7-8-22)28-12-10-24(27)18-31(28,30)17-23-9-11-25(34)16-26(23)30;/h2-6,9,11,16,22,24,27-28,34H,7-8,10,12-15,17-20H2,1H3;1H/t24-,27-,28+,30-,31-;/m1./s1 KHCZTDWYSGVKSZ-UVLAHWMYSA-N 50118191 CHEMBL3613173 Mu-type opioid receptor Cavia cutleri 0.197000 ChEMBL 10.1016/j.bmc.2015.08.036 10.7270/Q2V126M1 26346669 Nakajima, R; Yamamoto, N; Hirayama, S; Iwai, T; Saitoh, A; Nagumo, Y; Fujii, H; Nagase, H University of Tsukuba http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118191&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44352538 104011528 CHEMBL3613173 ZINC27310260 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50408293 Cl.CN([C@@H]1C[C@@]23CCN(CC4CC4)[C@H]4CC[C@@H]1C[C@@]24Cc1ccc(O)cc31)C(=O)CCc1ccccc1 InChI=1S/C32H40N2O2.ClH/c1-33(30(36)14-9-22-5-3-2-4-6-22)28-20-31-15-16-34(21-23-7-8-23)29-13-11-25(28)19-32(29,31)18-24-10-12-26(35)17-27(24)31;/h2-6,10,12,17,23,25,28-29,35H,7-9,11,13-16,18-21H2,1H3;1H/t25-,28-,29+,31-,32-;/m1./s1 LNQRQQNRENNENZ-ZKLLXXQBSA-N 50118178 CHEMBL3613172 Mu-type opioid receptor Cavia cutleri 0.229000 ChEMBL 10.1016/j.bmc.2015.08.036 10.7270/Q2V126M1 26346669 Nakajima, R; Yamamoto, N; Hirayama, S; Iwai, T; Saitoh, A; Nagumo, Y; Fujii, H; Nagase, H University of Tsukuba http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118178 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118178&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44352568 104011515 CHEMBL3613172 ZINC27319859 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50408294 Cl.CN([C@@H]1C[C@@]23CCN(CC4CC4)[C@H]4CC[C@@H]1C[C@@]24Cc1ccc(O)cc31)C(=O)\C=C\c1ccoc1 InChI=1S/C30H36N2O3.ClH/c1-31(28(34)9-4-21-10-13-35-19-21)26-17-29-11-12-32(18-20-2-3-20)27-8-6-23(26)16-30(27,29)15-22-5-7-24(33)14-25(22)29;/h4-5,7,9-10,13-14,19-20,23,26-27,33H,2-3,6,8,11-12,15-18H2,1H3;1H/b9-4+;/t23-,26-,27+,29-,30-;/m1./s1 JXWCMWQRMRFPLA-PYRSVMMESA-N 50118177 CHEMBL3613171 Mu-type opioid receptor Cavia cutleri 0.232000 ChEMBL 10.1016/j.bmc.2015.08.036 10.7270/Q2V126M1 26346669 Nakajima, R; Yamamoto, N; Hirayama, S; Iwai, T; Saitoh, A; Nagumo, Y; Fujii, H; Nagase, H University of Tsukuba http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118177 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118177&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44352876 104011514 CHEMBL3613171 ZINC27329808 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50408295 Cl.CN([C@H]1C[C@@]23CCN(CC4CC4)[C@H]4C=C[C@@H]1C[C@@]24Cc1ccc(O)cc31)C(=O)c1ccccc1 InChI=1S/C30H34N2O2.ClH/c1-31(28(34)21-5-3-2-4-6-21)26-18-29-13-14-32(19-20-7-8-20)27-12-10-23(26)17-30(27,29)16-22-9-11-24(33)15-25(22)29;/h2-6,9-12,15,20,23,26-27,33H,7-8,13-14,16-19H2,1H3;1H/t23-,26+,27+,29-,30-;/m1./s1 BZHSMEWFZDVZAT-VFTKGZTKSA-N 50118176 CHEMBL3613170 Mu-type opioid receptor Cavia cutleri 48 ChEMBL 10.1016/j.bmc.2015.08.036 10.7270/Q2V126M1 26346669 Nakajima, R; Yamamoto, N; Hirayama, S; Iwai, T; Saitoh, A; Nagumo, Y; Fujii, H; Nagase, H University of Tsukuba http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118176&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44352677 104011513 CHEMBL3613170 ZINC27318731 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50408296 CC1(C)C2CCC1(CS(O)(=O)=O)C(=O)C2.CN([C@H]1C[C@@]23CCN(CC4CC4)[C@H]4C=C[C@@H]1C[C@@]24Cc1ccc(O)cc31)C(=O)Cc1ccccc1 InChI=1S/C31H36N2O2.C10H16O4S/c1-32(29(35)15-21-5-3-2-4-6-21)27-19-30-13-14-33(20-22-7-8-22)28-12-10-24(27)18-31(28,30)17-23-9-11-25(34)16-26(23)30;1-9(2)7-3-4-10(9,8(11)5-7)6-15(12,13)14/h2-6,9-12,16,22,24,27-28,34H,7-8,13-15,17-20H2,1H3;7H,3-6H2,1-2H3,(H,12,13,14)/t24-,27+,28+,30-,31-;/m1./s1 MFMBQOYXVBNXQJ-VWNIWGECSA-N 50118175 CHEMBL3613169 Mu-type opioid receptor Cavia cutleri 12 ChEMBL 10.1016/j.bmc.2015.08.036 10.7270/Q2V126M1 26346669 Nakajima, R; Yamamoto, N; Hirayama, S; Iwai, T; Saitoh, A; Nagumo, Y; Fujii, H; Nagase, H University of Tsukuba http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118175 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118175&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44352502 104011512 CHEMBL3613169 ZINC27323821 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50408297 CC1(C)C2CCC1(CS(O)(=O)=O)C(=O)C2.CN([C@H]1C[C@@]23CCN(CC4CC4)[C@H]4C=C[C@@H]1C[C@@]24Cc1ccc(O)cc31)C(=O)CCc1ccccc1 InChI=1S/C32H38N2O2.C10H16O4S/c1-33(30(36)14-9-22-5-3-2-4-6-22)28-20-31-15-16-34(21-23-7-8-23)29-13-11-25(28)19-32(29,31)18-24-10-12-26(35)17-27(24)31;1-9(2)7-3-4-10(9,8(11)5-7)6-15(12,13)14/h2-6,10-13,17,23,25,28-29,35H,7-9,14-16,18-21H2,1H3;7H,3-6H2,1-2H3,(H,12,13,14)/t25-,28+,29+,31-,32-;/m1./s1 DXZGRYLXICSYEN-WWOYOULDSA-N 50118179 CHEMBL3613168 Mu-type opioid receptor Cavia cutleri 4.4 ChEMBL 10.1016/j.bmc.2015.08.036 10.7270/Q2V126M1 26346669 Nakajima, R; Yamamoto, N; Hirayama, S; Iwai, T; Saitoh, A; Nagumo, Y; Fujii, H; Nagase, H University of Tsukuba http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118179 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118179&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44352539 104011516 CHEMBL3613168 ZINC27310748 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50408298 Cl.CN([C@H]1C[C@@]23CCN(CC4CC4)[C@H]4C=C[C@@H]1C[C@@]24Cc1ccc(O)cc31)C(=O)\C=C\c1ccoc1 InChI=1S/C30H34N2O3.ClH/c1-31(28(34)9-4-21-10-13-35-19-21)26-17-29-11-12-32(18-20-2-3-20)27-8-6-23(26)16-30(27,29)15-22-5-7-24(33)14-25(22)29;/h4-10,13-14,19-20,23,26-27,33H,2-3,11-12,15-18H2,1H3;1H/b9-4+;/t23-,26+,27+,29-,30-;/m1./s1 CXRSLAPJNNXWPN-RWIWYQPJSA-N 50118180 CHEMBL3613167 Mu-type opioid receptor Cavia cutleri 14 ChEMBL 10.1016/j.bmc.2015.08.036 10.7270/Q2V126M1 26346669 Nakajima, R; Yamamoto, N; Hirayama, S; Iwai, T; Saitoh, A; Nagumo, Y; Fujii, H; Nagase, H University of Tsukuba http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118180 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118180&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44352728 104011517 CHEMBL3613167 ZINC36177336 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50408299 Cl.CN([C@@H]1C[C@@]23CCN(CC4CC4)[C@H]4C=C[C@@H]1C[C@@]24Cc1ccc(O)cc31)C(=O)c1ccccc1 InChI=1S/C30H34N2O2.ClH/c1-31(28(34)21-5-3-2-4-6-21)26-18-29-13-14-32(19-20-7-8-20)27-12-10-23(26)17-30(27,29)16-22-9-11-24(33)15-25(22)29;/h2-6,9-12,15,20,23,26-27,33H,7-8,13-14,16-19H2,1H3;1H/t23-,26-,27+,29-,30-;/m1./s1 BZHSMEWFZDVZAT-PXUSUCDHSA-N 50118181 CHEMBL3613166 Mu-type opioid receptor Cavia cutleri 2.7 ChEMBL 10.1016/j.bmc.2015.08.036 10.7270/Q2V126M1 26346669 Nakajima, R; Yamamoto, N; Hirayama, S; Iwai, T; Saitoh, A; Nagumo, Y; Fujii, H; Nagase, H University of Tsukuba http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118181&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44352729 104011518 CHEMBL3613166 ZINC27323206 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50408300 CC1(C)C2CCC1(CS(O)(=O)=O)C(=O)C2.CN([C@@H]1C[C@@]23CCN(CC4CC4)[C@H]4C=C[C@@H]1C[C@@]24Cc1ccc(O)cc31)C(=O)Cc1ccccc1 InChI=1S/C31H36N2O2.C10H16O4S/c1-32(29(35)15-21-5-3-2-4-6-21)27-19-30-13-14-33(20-22-7-8-22)28-12-10-24(27)18-31(28,30)17-23-9-11-25(34)16-26(23)30;1-9(2)7-3-4-10(9,8(11)5-7)6-15(12,13)14/h2-6,9-12,16,22,24,27-28,34H,7-8,13-15,17-20H2,1H3;7H,3-6H2,1-2H3,(H,12,13,14)/t24-,27-,28+,30-,31-;/m1./s1 MFMBQOYXVBNXQJ-UVLAHWMYSA-N 50118182 CHEMBL3613165 Mu-type opioid receptor Cavia cutleri 0.420000 ChEMBL 10.1016/j.bmc.2015.08.036 10.7270/Q2V126M1 26346669 Nakajima, R; Yamamoto, N; Hirayama, S; Iwai, T; Saitoh, A; Nagumo, Y; Fujii, H; Nagase, H University of Tsukuba http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118182 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118182&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44352522 104011519 CHEMBL3613165 ZINC27321354 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50408301 Cl.CN([C@@H]1C[C@@]23CCN(CC4CC4)[C@H]4C=C[C@@H]1C[C@@]24Cc1ccc(O)cc31)C(=O)CCc1ccccc1 InChI=1S/C32H38N2O2.ClH/c1-33(30(36)14-9-22-5-3-2-4-6-22)28-20-31-15-16-34(21-23-7-8-23)29-13-11-25(28)19-32(29,31)18-24-10-12-26(35)17-27(24)31;/h2-6,10-13,17,23,25,28-29,35H,7-9,14-16,18-21H2,1H3;1H/t25-,28-,29+,31-,32-;/m1./s1 PPXQLQIKWKMUJM-ZKLLXXQBSA-N 50118183 CHEMBL3613164 Mu-type opioid receptor Cavia cutleri 0.510000 ChEMBL 10.1016/j.bmc.2015.08.036 10.7270/Q2V126M1 26346669 Nakajima, R; Yamamoto, N; Hirayama, S; Iwai, T; Saitoh, A; Nagumo, Y; Fujii, H; Nagase, H University of Tsukuba http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118183 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118183&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44352569 104011520 CHEMBL3613164 ZINC27318934 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50408302 Cl.CN([C@@H]1C[C@@]23CCN(CC4CC4)[C@H]4C=C[C@@H]1C[C@@]24Cc1ccc(O)cc31)C(=O)\C=C\c1ccoc1 InChI=1S/C30H34N2O3.ClH/c1-31(28(34)9-4-21-10-13-35-19-21)26-17-29-11-12-32(18-20-2-3-20)27-8-6-23(26)16-30(27,29)15-22-5-7-24(33)14-25(22)29;/h4-10,13-14,19-20,23,26-27,33H,2-3,11-12,15-18H2,1H3;1H/b9-4+;/t23-,26-,27+,29-,30-;/m1./s1 CXRSLAPJNNXWPN-PYRSVMMESA-N 50118184 CHEMBL3613163 Mu-type opioid receptor Cavia cutleri 0.570000 ChEMBL 10.1016/j.bmc.2015.08.036 10.7270/Q2V126M1 26346669 Nakajima, R; Yamamoto, N; Hirayama, S; Iwai, T; Saitoh, A; Nagumo, Y; Fujii, H; Nagase, H University of Tsukuba http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118184 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118184&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44352583 104011521 CHEMBL3613163 ZINC27321366 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50408303 CN([C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45)C(=O)\C=C\c1ccoc1 InChI=1S/C28H32N2O5/c1-29(23(32)7-4-18-9-13-34-16-18)20-8-10-28(33)22-14-19-5-6-21(31)25-24(19)27(28,26(20)35-25)11-12-30(22)15-17-2-3-17/h4-7,9,13,16-17,20,22,26,31,33H,2-3,8,10-12,14-15H2,1H3/b7-4+/t20-,22-,26+,27+,28-/m1/s1 XGZZHZMWIXFATA-UEZBDDGYSA-N 50274347 (2E)-N-[(5R,6R)-17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-yl]-3-(furan-3-yl)-N-methylprop-2-enamide hydrochloride::CHEMBL490665::US10377763, Example 1 Mu-type opioid receptor Cavia cutleri 0.431000 ChEMBL 10.1016/j.bmc.2015.08.036 10.7270/Q2V126M1 26346669 Nakajima, R; Yamamoto, N; Hirayama, S; Iwai, T; Saitoh, A; Nagumo, Y; Fujii, H; Nagase, H University of Tsukuba http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274347&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search IVB 7YIT 6445230 104118157 CHEMBL490665 ZINC04393014 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50399824 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)NCCN InChI=1S/C23H30N4O3/c1-14-9-18(28)10-15(2)19(14)12-20(25)23(30)27-13-17-6-4-3-5-16(17)11-21(27)22(29)26-8-7-24/h3-6,9-10,20-21,28H,7-8,11-13,24-25H2,1-2H3,(H,26,29)/t20-,21?/m0/s1 VIPTXSCSZKOVSA-BGERDNNASA-N 50221985 CHEMBL241010::H-Dmt-Tic-NH-CH2-CH2-NH2 Mu-type opioid receptor Cavia cutleri 285.6 ChEMBL 10.1016/j.bmc.2007.08.047 10.7270/Q2XD11D9 17851080 Salvadori, S; Trapella, C; Fiorini, S; Negri, L; Lattanzi, R; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Balboni, G University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221985 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221985&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44436392 104094490 CHEMBL241010 ZINC28866950 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50399826 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)NCCNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C55H64N8O8/c1-34-26-42(65)27-35(2)43(34)32-45(57)55(71)63-33-40-17-10-9-16-39(40)31-49(63)52(68)59-24-23-58-50(66)46(29-36-12-5-3-6-13-36)60-51(67)47(30-37-14-7-4-8-15-37)61-53(69)48-18-11-25-62(48)54(70)44(56)28-38-19-21-41(64)22-20-38/h3-10,12-17,19-22,26-27,44-49,64-65H,11,18,23-25,28-33,56-57H2,1-2H3,(H,58,66)(H,59,68)(H,60,67)(H,61,69)/t44-,45-,46-,47-,48-,49?/m0/s1 CJBITXMCHBQEBZ-PGXNEIGQSA-N 50221986 CHEMBL392469::H-Tyr-Pro-Phe-Phe-NH-CH2-CH2-NH Tic Dmt-H Mu-type opioid receptor Cavia cutleri 25.1 ChEMBL 10.1016/j.bmc.2007.08.047 10.7270/Q2XD11D9 17851080 Salvadori, S; Trapella, C; Fiorini, S; Negri, L; Lattanzi, R; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Balboni, G University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221986 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221986&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44436371 104094491 CHEMBL392469 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50398822 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCc1nc(C)c(C)[nH]c1=O InChI=1S/C19H26N4O3/c1-10-7-14(24)8-11(2)15(10)9-16(20)18(25)21-6-5-17-19(26)23-13(4)12(3)22-17/h7-8,16,24H,5-6,9,20H2,1-4H3,(H,21,25)(H,23,26)/t16-/m0/s1 PIBSPZBPWRXUQW-INIZCTEOSA-N 50221421 (S)-2-amino-N-(2-(5,6-dimethyl-3-oxo-3,4-dihydropyrazin-2-yl)ethyl)-3-(4-hydroxy-2,6-dimethylphenyl)propanamide::CHEMBL236253 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1016/j.bmcl.2007.08.058 10.7270/Q2N29WPB 17826995 Shiotani, K; Li, T; Miyazaki, A; Tsuda, Y; Yokoi, T; Ambo, A; Sasaki, Y; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221421 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221421&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44434330 104094078 CHEMBL236253 ZINC28825452 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50398824 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCc1nc(C)c(C)[nH]c1=O InChI=1S/C20H28N4O3/c1-11-8-15(25)9-12(2)16(11)10-17(21)19(26)22-7-5-6-18-20(27)24-14(4)13(3)23-18/h8-9,17,25H,5-7,10,21H2,1-4H3,(H,22,26)(H,24,27)/t17-/m0/s1 HWDRXUZQHRTTNY-KRWDZBQOSA-N 50221422 (S)-2-amino-N-(3-(5,6-dimethyl-3-oxo-3,4-dihydropyrazin-2-yl)propyl)-3-(4-hydroxy-2,6-dimethylphenyl)propanamide::CHEMBL437372 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1016/j.bmcl.2007.08.058 10.7270/Q2N29WPB 17826995 Shiotani, K; Li, T; Miyazaki, A; Tsuda, Y; Yokoi, T; Ambo, A; Sasaki, Y; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221422&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44434329 104094079 CHEMBL437372 ZINC28825451 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50398830 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCCc1nc(C)c(C)[nH]c1=O InChI=1S/C21H30N4O3/c1-12-9-16(26)10-13(2)17(12)11-18(22)20(27)23-8-6-5-7-19-21(28)25-15(4)14(3)24-19/h9-10,18,26H,5-8,11,22H2,1-4H3,(H,23,27)(H,25,28)/t18-/m0/s1 TWSRDAXUNZOGLO-SFHVURJKSA-N 50221428 (S)-2-amino-N-(4-(5,6-dimethyl-3-oxo-3,4-dihydropyrazin-2-yl)butyl)-3-(4-hydroxy-2,6-dimethylphenyl)propanamide::CHEMBL413703 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1016/j.bmcl.2007.08.058 10.7270/Q2N29WPB 17826995 Shiotani, K; Li, T; Miyazaki, A; Tsuda, Y; Yokoi, T; Ambo, A; Sasaki, Y; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221428 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221428&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44434327 104094085 CHEMBL413703 ZINC28825448 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50398836 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCc1nc(C)c(C)[nH]c1=O InChI=1S/C18H24N4O3/c1-9-5-13(23)6-10(2)14(9)7-15(19)17(24)20-8-16-18(25)22-12(4)11(3)21-16/h5-6,15,23H,7-8,19H2,1-4H3,(H,20,24)(H,22,25)/t15-/m0/s1 WDZPUCTUFBNLJB-HNNXBMFYSA-N 50221426 (S)-2-amino-N-((5,6-dimethyl-3-oxo-3,4-dihydropyrazin-2-yl)methyl)-3-(4-hydroxy-2,6-dimethylphenyl)propanamide::CHEMBL236460 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1016/j.bmcl.2007.08.058 10.7270/Q2N29WPB 17826995 Shiotani, K; Li, T; Miyazaki, A; Tsuda, Y; Yokoi, T; Ambo, A; Sasaki, Y; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221426 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221426&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44434331 104094083 CHEMBL236460 ZINC28825453 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50398841 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCCc1[nH]c(=O)cnc1C InChI=1S/C20H28N4O3/c1-12-8-15(25)9-13(2)16(12)10-17(21)20(27)22-7-5-4-6-18-14(3)23-11-19(26)24-18/h8-9,11,17,25H,4-7,10,21H2,1-3H3,(H,22,27)(H,24,26)/t17-/m0/s1 WHUBOKOSZQHFMF-KRWDZBQOSA-N 50221427 (S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-(4-(3-methyl-6-oxo-1,6-dihydropyrazin-2-yl)butyl)propanamide::CHEMBL236868 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1016/j.bmcl.2007.08.058 10.7270/Q2N29WPB 17826995 Shiotani, K; Li, T; Miyazaki, A; Tsuda, Y; Yokoi, T; Ambo, A; Sasaki, Y; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221427 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221427&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44434326 104094084 CHEMBL236868 ZINC28825447 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50398846 Cc1cccc(C)c1Cc1[nH]c(=O)c(CCCCNC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)nc1C InChI=1S/C29H38N4O3/c1-17-9-8-10-18(2)24(17)16-27-21(5)32-26(29(36)33-27)11-6-7-12-31-28(35)25(30)15-23-19(3)13-22(34)14-20(23)4/h8-10,13-14,25,34H,6-7,11-12,15-16,30H2,1-5H3,(H,31,35)(H,33,36)/t25-/m0/s1 PFRMPRUILAXAIG-VWLOTQADSA-N 50221418 (S)-N-(4-(5-(2,6-dimethylbenzyl)-6-methyl-3-oxo-3,4-dihydropyrazin-2-yl)butyl)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanamide::CHEMBL236663 Mu-type opioid receptor Cavia cutleri 6273 ChEMBL 10.1016/j.bmcl.2007.08.058 10.7270/Q2N29WPB 17826995 Shiotani, K; Li, T; Miyazaki, A; Tsuda, Y; Yokoi, T; Ambo, A; Sasaki, Y; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221418 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221418&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44434336 104094075 CHEMBL236663 ZINC28825458 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50398847 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCCc1nc(C)c(Cc2ccccc2)[nH]c1=O InChI=1S/C27H34N4O3/c1-17-13-21(32)14-18(2)22(17)16-23(28)26(33)29-12-8-7-11-24-27(34)31-25(19(3)30-24)15-20-9-5-4-6-10-20/h4-6,9-10,13-14,23,32H,7-8,11-12,15-16,28H2,1-3H3,(H,29,33)(H,31,34)/t23-/m0/s1 PGAGKGJAPYCCML-QHCPKHFHSA-N 50221419 (S)-2-amino-N-(4-(5-benzyl-6-methyl-3-oxo-3,4-dihydropyrazin-2-yl)butyl)-3-(4-hydroxy-2,6-dimethylphenyl)propanamide::CHEMBL392057 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1016/j.bmcl.2007.08.058 10.7270/Q2N29WPB 17826995 Shiotani, K; Li, T; Miyazaki, A; Tsuda, Y; Yokoi, T; Ambo, A; Sasaki, Y; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221419 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221419&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44434333 104094076 CHEMBL392057 ZINC28825455 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50398850 Cc1c[nH]c(=O)c(CCCCNC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)n1 InChI=1S/C20H28N4O3/c1-12-8-15(25)9-13(2)16(12)10-17(21)19(26)22-7-5-4-6-18-20(27)23-11-14(3)24-18/h8-9,11,17,25H,4-7,10,21H2,1-3H3,(H,22,26)(H,23,27)/t17-/m0/s1 JBAQDPIFUIUCNE-KRWDZBQOSA-N 50221420 (S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-(4-(6-methyl-3-oxo-3,4-dihydropyrazin-2-yl)butyl)propanamide::CHEMBL392828 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1016/j.bmcl.2007.08.058 10.7270/Q2N29WPB 17826995 Shiotani, K; Li, T; Miyazaki, A; Tsuda, Y; Yokoi, T; Ambo, A; Sasaki, Y; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221420 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221420&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44434325 104094077 CHEMBL392828 ZINC28825446 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50398852 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCCc1[nH]c(=O)c(C)nc1C InChI=1S/C21H30N4O3/c1-12-9-16(26)10-13(2)17(12)11-18(22)21(28)23-8-6-5-7-19-14(3)24-15(4)20(27)25-19/h9-10,18,26H,5-8,11,22H2,1-4H3,(H,23,28)(H,25,27)/t18-/m0/s1 DTNHVTPFYKNWRV-SFHVURJKSA-N 50221425 (S)-2-amino-N-(4-(3,5-dimethyl-6-oxo-1,6-dihydropyrazin-2-yl)butyl)-3-(4-hydroxy-2,6-dimethylphenyl)propanamide::CHEMBL237074 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1016/j.bmcl.2007.08.058 10.7270/Q2N29WPB 17826995 Shiotani, K; Li, T; Miyazaki, A; Tsuda, Y; Yokoi, T; Ambo, A; Sasaki, Y; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221425 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221425&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44434328 104094082 CHEMBL237074 ZINC28825450 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50398854 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCCc1nc(C)c(CCc2ccccc2)[nH]c1=O InChI=1S/C28H36N4O3/c1-18-15-22(33)16-19(2)23(18)17-24(29)27(34)30-14-8-7-11-26-28(35)32-25(20(3)31-26)13-12-21-9-5-4-6-10-21/h4-6,9-10,15-16,24,33H,7-8,11-14,17,29H2,1-3H3,(H,30,34)(H,32,35)/t24-/m0/s1 WWIITMRTVKXCDD-DEOSSOPVSA-N 50221423 (S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-(4-(6-methyl-3-oxo-5-phenethyl-3,4-dihydropyrazin-2-yl)butyl)propanamide::CHEMBL236662 Mu-type opioid receptor Cavia cutleri 16 ChEMBL 10.1016/j.bmcl.2007.08.058 10.7270/Q2N29WPB 17826995 Shiotani, K; Li, T; Miyazaki, A; Tsuda, Y; Yokoi, T; Ambo, A; Sasaki, Y; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221423 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221423&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44434335 104094080 CHEMBL236662 ZINC28825457 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50398859 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCc1nc(C)c(CCc2ccccc2)[nH]c1=O InChI=1S/C27H34N4O3/c1-17-14-21(32)15-18(2)22(17)16-23(28)26(33)29-13-7-10-25-27(34)31-24(19(3)30-25)12-11-20-8-5-4-6-9-20/h4-6,8-9,14-15,23,32H,7,10-13,16,28H2,1-3H3,(H,29,33)(H,31,34)/t23-/m0/s1 RMDHBUSXNKWAQY-QHCPKHFHSA-N 50221429 (S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-(3-(6-methyl-3-oxo-5-phenethyl-3,4-dihydropyrazin-2-yl)propyl)propanamide::CHEMBL236462 Mu-type opioid receptor Cavia cutleri 5547 ChEMBL 10.1016/j.bmcl.2007.08.058 10.7270/Q2N29WPB 17826995 Shiotani, K; Li, T; Miyazaki, A; Tsuda, Y; Yokoi, T; Ambo, A; Sasaki, Y; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221429 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221429&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44434334 104094086 CHEMBL236462 ZINC28825456 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50398863 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCCCc1nc(C)c(Cc2ccccc2)[nH]c1=O InChI=1S/C26H32N4O3/c1-16-12-20(31)13-17(2)21(16)15-22(27)25(32)28-11-7-10-23-26(33)30-24(18(3)29-23)14-19-8-5-4-6-9-19/h4-6,8-9,12-13,22,31H,7,10-11,14-15,27H2,1-3H3,(H,28,32)(H,30,33)/t22-/m0/s1 JEGWUGKGNRTWAQ-QFIPXVFZSA-N 50221424 (S)-2-amino-N-(3-(5-benzyl-6-methyl-3-oxo-3,4-dihydropyrazin-2-yl)propyl)-3-(4-hydroxy-2,6-dimethylphenyl)propanamide::CHEMBL236461 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1016/j.bmcl.2007.08.058 10.7270/Q2N29WPB 17826995 Shiotani, K; Li, T; Miyazaki, A; Tsuda, Y; Yokoi, T; Ambo, A; Sasaki, Y; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221424 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221424&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44434332 104094081 CHEMBL236461 ZINC28825454 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50409684 OC(=O)C(F)(F)F.CCC(=O)N(C1CCN(Cc2ccc3[C@H](N)CCCc3c2)CC1)c1ccccc1 InChI=1S/C25H33N3O.C2HF3O2/c1-2-25(29)28(21-8-4-3-5-9-21)22-13-15-27(16-14-22)18-19-11-12-23-20(17-19)7-6-10-24(23)26;3-2(4,5)1(6)7/h3-5,8-9,11-12,17,22,24H,2,6-7,10,13-16,18,26H2,1H3;(H,6,7)/t24-;/m1./s1 AHMIMHSFVOEQKB-GJFSDDNBSA-N 50119519 CHEMBL3613884 Mu-type opioid receptor Cavia cutleri 1020 ChEMBL 10.1016/j.bmc.2015.07.071 10.7270/Q2S46TSN 26299827 Deekonda, S; Wugalter, L; Kulkarni, V; Rankin, D; Largent-Milnes, TM; Davis, P; Bassirirad, NM; Lai, J; Vanderah, TW; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119519 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119519&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 122189401 319565858 CHEMBL3613884 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50409685 CCC(=O)N(C1CCN(Cc2ccc3[C@@H](O)CCCc3c2)CC1)c1ccccc1 InChI=1S/C25H32N2O2/c1-2-25(29)27(21-8-4-3-5-9-21)22-13-15-26(16-14-22)18-19-11-12-23-20(17-19)7-6-10-24(23)28/h3-5,8-9,11-12,17,22,24,28H,2,6-7,10,13-16,18H2,1H3/t24-/m0/s1 FDNVARBCVAIKSE-DEOSSOPVSA-N 50119525 CHEMBL3613882 Mu-type opioid receptor Cavia cutleri 55 ChEMBL 10.1016/j.bmc.2015.07.071 10.7270/Q2S46TSN 26299827 Deekonda, S; Wugalter, L; Kulkarni, V; Rankin, D; Largent-Milnes, TM; Davis, P; Bassirirad, NM; Lai, J; Vanderah, TW; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119525 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119525&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 122189397 319565861 CHEMBL3613882 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50409686 CCC(=O)N(CC1CCN(Cc2ccc3[C@@H](O)CCCc3c2)CC1)c1ccccc1 InChI=1S/C26H34N2O2/c1-2-26(30)28(23-8-4-3-5-9-23)19-20-13-15-27(16-14-20)18-21-11-12-24-22(17-21)7-6-10-25(24)29/h3-5,8-9,11-12,17,20,25,29H,2,6-7,10,13-16,18-19H2,1H3/t25-/m0/s1 MTYYLZNJETVGMC-VWLOTQADSA-N 50119526 CHEMBL3613883 Mu-type opioid receptor Cavia cutleri 600 ChEMBL 10.1016/j.bmc.2015.07.071 10.7270/Q2S46TSN 26299827 Deekonda, S; Wugalter, L; Kulkarni, V; Rankin, D; Largent-Milnes, TM; Davis, P; Bassirirad, NM; Lai, J; Vanderah, TW; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119526 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119526&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 122189398 319565862 CHEMBL3613883 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50409687 OC(=O)C(F)(F)F.CCC(=O)N(C1CCN(Cc2ccc3[C@H](N)CCCc3c2)CC1)c1ccc(F)c(F)c1 InChI=1S/C25H31F2N3O.C2HF3O2/c1-2-25(31)30(20-7-9-22(26)23(27)15-20)19-10-12-29(13-11-19)16-17-6-8-21-18(14-17)4-3-5-24(21)28;3-2(4,5)1(6)7/h6-9,14-15,19,24H,2-5,10-13,16,28H2,1H3;(H,6,7)/t24-;/m1./s1 PHOLQTOCUNZALP-GJFSDDNBSA-N 50119527 CHEMBL3612086 Mu-type opioid receptor Cavia cutleri 1100 ChEMBL 10.1016/j.bmc.2015.07.071 10.7270/Q2S46TSN 26299827 Deekonda, S; Wugalter, L; Kulkarni, V; Rankin, D; Largent-Milnes, TM; Davis, P; Bassirirad, NM; Lai, J; Vanderah, TW; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119527 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119527&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 122189399 319565863 CHEMBL3612086 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50409691 CCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 InChI=1S/C22H28N2O/c1-2-22(25)24(20-11-7-4-8-12-20)21-14-17-23(18-15-21)16-13-19-9-5-3-6-10-19/h3-12,21H,2,13-18H2,1H3 PJMPHNIQZUBGLI-UHFFFAOYSA-N 50008984 4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-phthalazin-1-one::CHEMBL596::Duragesic-100::Duragesic-12::Duragesic-25::Duragesic-50::Duragesic-75::FENTANYL::FENTANYL CITRATE::FENTANYL-HCl::Fentanyl-100::Fentanyl-12::Fentanyl-25::Fentanyl-50::Fentanyl-75::Fentora::Innovar::Ionsys::N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide::N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide(Fentanyl)::N-(1-phenethylpiperidin-4-yl)-N-phenylpropionamide Mu-type opioid receptor Cavia cutleri 9.5 ChEMBL 10.1016/j.bmc.2015.07.071 10.7270/Q2S46TSN 26299827 Deekonda, S; Wugalter, L; Kulkarni, V; Rankin, D; Largent-Milnes, TM; Davis, P; Bassirirad, NM; Lai, J; Vanderah, TW; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008984&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 7V7 5TZO,8EF5,7U64 3345 103922051 119915 CHEMBL596 DB00813 1626 ZINC02522669 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50416683 CCC(=O)N(C1CCN(Cc2ccc3[C@H](N)CCCc3c2)CC1)c1ccccc1 InChI=1S/C25H33N3O/c1-2-25(29)28(21-8-4-3-5-9-21)22-13-15-27(16-14-22)18-19-11-12-23-20(17-19)7-6-10-24(23)26/h3-5,8-9,11-12,17,22,24H,2,6-7,10,13-16,18,26H2,1H3/t24-/m1/s1 VBCZHLDOYLCXOK-XMMPIXPASA-N 50122045 CHEMBL3614086 Mu-type opioid receptor Cavia cutleri 1000 ChEMBL 10.1016/j.bmcl.2015.07.064 10.7270/Q2N29ZR2 26323872 Deekonda, S; Wugalter, L; Rankin, D; Largent-Milnes, TM; Davis, P; Wang, Y; Bassirirad, NM; Lai, J; Kulkarni, V; Vanderah, TW; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122045&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 122189402 104014758 CHEMBL3614086 ZINC27645237 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50416684 CCC(=O)N(CC1CCN(Cc2ccc3[C@@H](CCCc3c2)NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc2ccc(O)cc2)CC1)c1ccccc1 InChI=1S/C49H61N7O6/c1-3-46(59)56(39-14-8-5-9-15-39)32-36-23-25-55(26-24-36)31-37-19-22-41-38(27-37)13-10-16-43(41)54-49(62)44(29-34-11-6-4-7-12-34)53-45(58)30-51-47(60)33(2)52-48(61)42(50)28-35-17-20-40(57)21-18-35/h4-9,11-12,14-15,17-22,27,33,36,42-44,57H,3,10,13,16,23-26,28-32,50H2,1-2H3,(H,51,60)(H,52,61)(H,53,58)(H,54,62)/t33-,42+,43-,44+/m1/s1 HWRPIPZSOBLKRE-YUYOIQRKSA-N 50122051 CHEMBL3617467 Mu-type opioid receptor Cavia cutleri 190 ChEMBL 10.1016/j.bmcl.2015.07.064 10.7270/Q2N29ZR2 26323872 Deekonda, S; Wugalter, L; Rankin, D; Largent-Milnes, TM; Davis, P; Wang, Y; Bassirirad, NM; Lai, J; Kulkarni, V; Vanderah, TW; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122051&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 122190289 104014764 CHEMBL3617467 ZINC27646550 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50416685 CCC(=O)N(C1CCN(CCc2ccc3[C@@H](CCCc3c2)NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc2ccc(O)cc2)CC1)c1ccccc1 InChI=1S/C49H61N7O6/c1-3-46(59)56(38-14-8-5-9-15-38)39-24-27-55(28-25-39)26-23-36-19-22-41-37(29-36)13-10-16-43(41)54-49(62)44(31-34-11-6-4-7-12-34)53-45(58)32-51-47(60)33(2)52-48(61)42(50)30-35-17-20-40(57)21-18-35/h4-9,11-12,14-15,17-22,29,33,39,42-44,57H,3,10,13,16,23-28,30-32,50H2,1-2H3,(H,51,60)(H,52,61)(H,53,58)(H,54,62)/t33-,42+,43-,44+/m1/s1 IYOSRBUHFCAZEI-YUYOIQRKSA-N 50122052 CHEMBL3617468 Mu-type opioid receptor Cavia cutleri 150 ChEMBL 10.1016/j.bmcl.2015.07.064 10.7270/Q2N29ZR2 26323872 Deekonda, S; Wugalter, L; Rankin, D; Largent-Milnes, TM; Davis, P; Wang, Y; Bassirirad, NM; Lai, J; Kulkarni, V; Vanderah, TW; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122052 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122052&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 122190290 104014765 CHEMBL3617468 ZINC27637096 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50416686 CCC(=O)N(C1CCN(Cc2ccc3[C@@H](CCCc3c2)NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc2ccc(O)cc2)CC1)c1ccccc1 InChI=1S/C48H59N7O6/c1-3-45(58)55(37-14-8-5-9-15-37)38-23-25-54(26-24-38)31-35-19-22-40-36(27-35)13-10-16-42(40)53-48(61)43(29-33-11-6-4-7-12-33)52-44(57)30-50-46(59)32(2)51-47(60)41(49)28-34-17-20-39(56)21-18-34/h4-9,11-12,14-15,17-22,27,32,38,41-43,56H,3,10,13,16,23-26,28-31,49H2,1-2H3,(H,50,59)(H,51,60)(H,52,57)(H,53,61)/t32-,41+,42-,43+/m1/s1 UGWNTLZVLZDQMG-YSROBQEJSA-N 50122060 CHEMBL3617469 Mu-type opioid receptor Cavia cutleri 210 ChEMBL 10.1016/j.bmcl.2015.07.064 10.7270/Q2N29ZR2 26323872 Deekonda, S; Wugalter, L; Rankin, D; Largent-Milnes, TM; Davis, P; Wang, Y; Bassirirad, NM; Lai, J; Kulkarni, V; Vanderah, TW; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122060 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122060&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 122190291 104014773 CHEMBL3617469 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50416687 CCC(=O)N(C1CCN(Cc2cccc3[C@@H](CCCc23)NC(=O)CCNC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc2ccc(O)cc2)CC1)c1ccccc1 InChI=1S/C51H64N8O7/c1-3-48(63)59(38-15-8-5-9-16-38)39-25-28-58(29-26-39)33-37-14-10-18-42-41(37)17-11-19-44(42)56-46(61)24-27-53-51(66)45(31-35-12-6-4-7-13-35)57-47(62)32-54-49(64)34(2)55-50(65)43(52)30-36-20-22-40(60)23-21-36/h4-10,12-16,18,20-23,34,39,43-45,60H,3,11,17,19,24-33,52H2,1-2H3,(H,53,66)(H,54,64)(H,55,65)(H,56,61)(H,57,62)/t34-,43+,44-,45+/m1/s1 ZDSCNXMYLDWNIC-KYOPYDKYSA-N 50122064 CHEMBL3617470 Mu-type opioid receptor Cavia cutleri 10.0 ChEMBL 10.1016/j.bmcl.2015.07.064 10.7270/Q2N29ZR2 26323872 Deekonda, S; Wugalter, L; Rankin, D; Largent-Milnes, TM; Davis, P; Wang, Y; Bassirirad, NM; Lai, J; Kulkarni, V; Vanderah, TW; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122064&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 122190292 104014777 CHEMBL3617470 ZINC28109322 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50416688 CCC(=O)N(C1CCN(Cc2cccc3[C@@H](CCCc23)NC(=O)CCNC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)CC1)c1ccccc1 InChI=1S/C53H68N8O7/c1-5-50(65)61(39-17-10-7-11-18-39)40-23-26-60(27-24-40)33-38-16-12-20-43-42(38)19-13-21-46(43)58-48(63)22-25-55-53(68)47(30-37-14-8-6-9-15-37)59-49(64)32-56-51(66)36(4)57-52(67)45(54)31-44-34(2)28-41(62)29-35(44)3/h6-12,14-18,20,28-29,36,40,45-47,62H,5,13,19,21-27,30-33,54H2,1-4H3,(H,55,68)(H,56,66)(H,57,67)(H,58,63)(H,59,64)/t36-,45+,46-,47+/m1/s1 RKFZVNUOHJTUPP-FYFZTIDASA-N 50122099 CHEMBL3617471 Mu-type opioid receptor Cavia cutleri 4.6 ChEMBL 10.1016/j.bmcl.2015.07.064 10.7270/Q2N29ZR2 26323872 Deekonda, S; Wugalter, L; Rankin, D; Largent-Milnes, TM; Davis, P; Wang, Y; Bassirirad, NM; Lai, J; Kulkarni, V; Vanderah, TW; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122099 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122099&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 122190293 104014812 CHEMBL3617471 ZINC27648662 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50416689 CCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 InChI=1S/C22H28N2O/c1-2-22(25)24(20-11-7-4-8-12-20)21-14-17-23(18-15-21)16-13-19-9-5-3-6-10-19/h3-12,21H,2,13-18H2,1H3 PJMPHNIQZUBGLI-UHFFFAOYSA-N 50008984 4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-phthalazin-1-one::CHEMBL596::Duragesic-100::Duragesic-12::Duragesic-25::Duragesic-50::Duragesic-75::FENTANYL::FENTANYL CITRATE::FENTANYL-HCl::Fentanyl-100::Fentanyl-12::Fentanyl-25::Fentanyl-50::Fentanyl-75::Fentora::Innovar::Ionsys::N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide::N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide(Fentanyl)::N-(1-phenethylpiperidin-4-yl)-N-phenylpropionamide Mu-type opioid receptor Cavia cutleri 3.4 ChEMBL 10.1016/j.bmcl.2015.07.064 10.7270/Q2N29ZR2 26323872 Deekonda, S; Wugalter, L; Rankin, D; Largent-Milnes, TM; Davis, P; Wang, Y; Bassirirad, NM; Lai, J; Kulkarni, V; Vanderah, TW; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008984&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 7V7 5TZO,8EF5,7U64 3345 103922051 119915 CHEMBL596 DB00813 1626 ZINC02522669 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50416690 C[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C27H34N6O8/c1-15(25(39)30-14-22(35)32-20(24(29)38)12-16-5-3-2-4-6-16)31-27(41)21(13-23(36)37)33-26(40)19(28)11-17-7-9-18(34)10-8-17/h2-10,15,19-21,34H,11-14,28H2,1H3,(H2,29,38)(H,30,39)(H,31,41)(H,32,35)(H,33,40)(H,36,37)/t15-,19-,20-,21-/m0/s1 WSINNSBLQGGXAE-ZEWNOJEFSA-N 50122103 CHEMBL3617472 Mu-type opioid receptor Cavia cutleri 40 ChEMBL 10.1016/j.bmcl.2015.07.064 10.7270/Q2N29ZR2 26323872 Deekonda, S; Wugalter, L; Rankin, D; Largent-Milnes, TM; Davis, P; Wang, Y; Bassirirad, NM; Lai, J; Kulkarni, V; Vanderah, TW; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122103 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122103&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 122190294 104014816 CHEMBL3617472 ZINC27649290 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50443482 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H]1Cc2c(CN(CC(O)=O)C1=O)[nH]c1ccccc21 InChI=1S/C25H28N4O5/c1-13-7-15(30)8-14(2)17(13)9-19(26)24(33)28-21-10-18-16-5-3-4-6-20(16)27-22(18)11-29(25(21)34)12-23(31)32/h3-8,19,21,27,30H,9-12,26H2,1-2H3,(H,28,33)(H,31,32)/t19-,21-/m0/s1 CRPZPOFLOPEEFP-FPOVZHCZSA-N 50266062 2-((S)-4-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)-3-oxo-4,5-dihydroazepino[3,4-b]indol-2(1H,3H,10H)-yl)acetic acid::CHEMBL458208 Mu-type opioid receptor Cavia cutleri >20000 ChEMBL 10.1016/j.bmcl.2008.11.051 10.7270/Q2K64HZ7 19062273 Ballet, S; Feytens, D; Wachter, RD; Vlaeminck, MD; Marczak, ED; Salvadori, S; Graaf, C; Rognan, D; Negri, L; Lattanzi, R; Lazarus, LH; Tourwe, D; Balboni, G Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266062 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266062&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44581439 104113586 CHEMBL458208 ZINC40393583 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50443486 CN(C)[C@@H](Cc1c(C)cc(O)cc1C)C(=O)N[C@H]1Cc2c(CN(CC(O)=O)C1=O)[nH]c1ccccc21 InChI=1S/C27H32N4O5/c1-15-9-17(32)10-16(2)19(15)12-24(30(3)4)26(35)29-22-11-20-18-7-5-6-8-21(18)28-23(20)13-31(27(22)36)14-25(33)34/h5-10,22,24,28,32H,11-14H2,1-4H3,(H,29,35)(H,33,34)/t22-,24-/m0/s1 XTEHMRJXZGIECL-UPVQGACJSA-N 50266063 2-((S)-4-((S)-2-(dimethylamino)-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)-3-oxo-4,5-dihydroazepino[3,4-b]indol-2(1H,3H,10H)-yl)acetic acid::CHEMBL458417 Mu-type opioid receptor Cavia cutleri >20000 ChEMBL 10.1016/j.bmcl.2008.11.051 10.7270/Q2K64HZ7 19062273 Ballet, S; Feytens, D; Wachter, RD; Vlaeminck, MD; Marczak, ED; Salvadori, S; Graaf, C; Rognan, D; Negri, L; Lattanzi, R; Lazarus, LH; Tourwe, D; Balboni, G Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266063 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266063&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44581440 104113587 CHEMBL458417 ZINC40392945 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50443493 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCC(=O)NCc1ccccc1 InChI=1S/C30H34N4O4/c1-19-12-24(35)13-20(2)25(19)15-26(31)30(38)34-18-23-11-7-6-10-22(23)14-27(34)29(37)33-17-28(36)32-16-21-8-4-3-5-9-21/h3-13,26-27,35H,14-18,31H2,1-2H3,(H,32,36)(H,33,37)/t26-,27-/m0/s1 SYOVEDOWOXNOJG-SVBPBHIXSA-N 50266025 (S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-N-(2-(benzylamino)-2-oxoethyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid (benzylcarbamoyl-methyl)-amide::CHEMBL458631::H-Dmt-Tic-Gly-NH-Bzl::H-Dmt-Tic-Gly-NH-CH2-Ph Mu-type opioid receptor Cavia cutleri 2.69 ChEMBL 10.1016/j.bmcl.2008.11.051 10.7270/Q2K64HZ7 19062273 Ballet, S; Feytens, D; Wachter, RD; Vlaeminck, MD; Marczak, ED; Salvadori, S; Graaf, C; Rognan, D; Negri, L; Lattanzi, R; Lazarus, LH; Tourwe, D; Balboni, G Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266025&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10864183 104113557 CHEMBL458631 ZINC13472301 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50443496 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H]1Cc2ccccc2CN(CC(=O)NCc2ccccc2)C1=O InChI=1S/C30H34N4O4/c1-19-12-24(35)13-20(2)25(19)15-26(31)29(37)33-27-14-22-10-6-7-11-23(22)17-34(30(27)38)18-28(36)32-16-21-8-4-3-5-9-21/h3-13,26-27,35H,14-18,31H2,1-2H3,(H,32,36)(H,33,37)/t26-,27-/m0/s1 HAQFBGNRXYPSQF-SVBPBHIXSA-N 50189920 (S)-2-amino-N-((S)-2-(2-(benzylamino)-2-oxoethyl)-3-oxo-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-yl)-3-(4-hydroxy-2,6-dimethylphenyl)propanamide::CHEMBL208683::H-Dmt-Aba-Gly-NH-CH2-Ph Mu-type opioid receptor Cavia cutleri 51 ChEMBL 10.1016/j.bmcl.2008.11.051 10.7270/Q2K64HZ7 19062273 Ballet, S; Feytens, D; Wachter, RD; Vlaeminck, MD; Marczak, ED; Salvadori, S; Graaf, C; Rognan, D; Negri, L; Lattanzi, R; Lazarus, LH; Tourwe, D; Balboni, G Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189920&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11664525 104073372 CHEMBL208683 ZINC36221912 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50443500 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H]1Cc2ccccc2CN([C@@H](CCCCN)C(=O)NCc2ccccc2)C1=O InChI=1S/C34H43N5O4/c1-22-16-27(40)17-23(2)28(22)19-29(36)32(41)38-30-18-25-12-6-7-13-26(25)21-39(34(30)43)31(14-8-9-15-35)33(42)37-20-24-10-4-3-5-11-24/h3-7,10-13,16-17,29-31,40H,8-9,14-15,18-21,35-36H2,1-2H3,(H,37,42)(H,38,41)/t29-,30-,31-/m0/s1 IAPCGFXZQBWWFU-CHQNGUEUSA-N 50266026 (S)-6-amino-2-((S)-4-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)-3-oxo-4,5-dihydro-1H-benzo[c]azepin-2(3H)-yl)-N-benzylhexanamide::CHEMBL449224 Mu-type opioid receptor Cavia cutleri 3272 ChEMBL 10.1016/j.bmcl.2008.11.051 10.7270/Q2K64HZ7 19062273 Ballet, S; Feytens, D; Wachter, RD; Vlaeminck, MD; Marczak, ED; Salvadori, S; Graaf, C; Rognan, D; Negri, L; Lattanzi, R; Lazarus, LH; Tourwe, D; Balboni, G Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266026&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44581400 104113558 CHEMBL449224 ZINC44351262 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50443505 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H]1Cc2ccccc2CNC1=O InChI=1S/C21H25N3O3/c1-12-7-16(25)8-13(2)17(12)10-18(22)20(26)24-19-9-14-5-3-4-6-15(14)11-23-21(19)27/h3-8,18-19,25H,9-11,22H2,1-2H3,(H,23,27)(H,24,26)/t18-,19-/m0/s1 QBXKIGHVYCRJPK-OALUTQOASA-N 50266056 (S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-((S)-3-oxo-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-yl)propanamide::CHEMBL459280 Mu-type opioid receptor Cavia cutleri 631 ChEMBL 10.1016/j.bmcl.2008.11.051 10.7270/Q2K64HZ7 19062273 Ballet, S; Feytens, D; Wachter, RD; Vlaeminck, MD; Marczak, ED; Salvadori, S; Graaf, C; Rognan, D; Negri, L; Lattanzi, R; Lazarus, LH; Tourwe, D; Balboni, G Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266056 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266056&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44581433 104113580 CHEMBL459280 ZINC40864729 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50443509 CN(C)[C@@H](Cc1c(C)cc(O)cc1C)C(=O)N[C@H]1Cc2ccccc2CNC1=O InChI=1S/C23H29N3O3/c1-14-9-18(27)10-15(2)19(14)12-21(26(3)4)23(29)25-20-11-16-7-5-6-8-17(16)13-24-22(20)28/h5-10,20-21,27H,11-13H2,1-4H3,(H,24,28)(H,25,29)/t20-,21-/m0/s1 XNYZNBPSFSIZKH-SFTDATJTSA-N 50266057 (S)-2-(dimethylamino)-3-(4-hydroxy-2,6-dimethylphenyl)-N-((S)-3-oxo-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-yl)propanamide::CHEMBL459281 Mu-type opioid receptor Cavia cutleri >20000 ChEMBL 10.1016/j.bmcl.2008.11.051 10.7270/Q2K64HZ7 19062273 Ballet, S; Feytens, D; Wachter, RD; Vlaeminck, MD; Marczak, ED; Salvadori, S; Graaf, C; Rognan, D; Negri, L; Lattanzi, R; Lazarus, LH; Tourwe, D; Balboni, G Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266057 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266057&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44581434 104113581 CHEMBL459281 ZINC40864732 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50443512 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H]1Cc2c(CN(CC(=O)NCc3ccccc3)C1=O)[nH]c1ccccc21 InChI=1S/C32H35N5O4/c1-19-12-22(38)13-20(2)24(19)14-26(33)31(40)36-28-15-25-23-10-6-7-11-27(23)35-29(25)17-37(32(28)41)18-30(39)34-16-21-8-4-3-5-9-21/h3-13,26,28,35,38H,14-18,33H2,1-2H3,(H,34,39)(H,36,40)/t26-,28-/m0/s1 DGSVUCDQWMCAPS-XCZPVHLTSA-N 50266058 (S)-2-amino-N-((S)-2-(2-(benzylamino)-2-oxoethyl)-3-oxo-1,2,3,4,5,10-hexahydroazepino[3,4-b]indol-4-yl)-3-(4-hydroxy-2,6-dimethylphenyl)propanamide::CHEMBL446336 Mu-type opioid receptor Cavia cutleri 1795 ChEMBL 10.1016/j.bmcl.2008.11.051 10.7270/Q2K64HZ7 19062273 Ballet, S; Feytens, D; Wachter, RD; Vlaeminck, MD; Marczak, ED; Salvadori, S; Graaf, C; Rognan, D; Negri, L; Lattanzi, R; Lazarus, LH; Tourwe, D; Balboni, G Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266058 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266058&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44581435 104113582 CHEMBL446336 ZINC44281271 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50443515 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@@H]1Cc2c(CN(CC(=O)NCc3ccccc3)C1=O)[nH]c1ccccc21 InChI=1S/C32H35N5O4/c1-19-12-22(38)13-20(2)24(19)14-26(33)31(40)36-28-15-25-23-10-6-7-11-27(23)35-29(25)17-37(32(28)41)18-30(39)34-16-21-8-4-3-5-9-21/h3-13,26,28,35,38H,14-18,33H2,1-2H3,(H,34,39)(H,36,40)/t26-,28+/m0/s1 DGSVUCDQWMCAPS-XTEPFMGCSA-N 50266060 (S)-2-amino-N-((R)-2-(2-(benzylamino)-2-oxoethyl)-3-oxo-1,2,3,4,5,10-hexahydroazepino[3,4-b]indol-4-yl)-3-(4-hydroxy-2,6-dimethylphenyl)propanamide::CHEMBL506761 Mu-type opioid receptor Cavia cutleri 14.9 ChEMBL 10.1016/j.bmcl.2008.11.051 10.7270/Q2K64HZ7 19062273 Ballet, S; Feytens, D; Wachter, RD; Vlaeminck, MD; Marczak, ED; Salvadori, S; Graaf, C; Rognan, D; Negri, L; Lattanzi, R; Lazarus, LH; Tourwe, D; Balboni, G Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266060 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266060&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44581437 104113584 CHEMBL506761 ZINC42834592 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50433215 C[C@@H](O)[C@H](NC(=O)[C@H]1NC(=O)[C@@H](NC(=O)[C@H](CCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CSSC1(C)C)NC(=O)[C@H](N)Cc1ccccc1)[C@@H](C)O)C(N)=O InChI=1S/C50H67N11O11S2/c1-26(62)39(42(53)65)59-49(72)41-50(3,4)74-73-25-38(58-43(66)33(52)21-28-11-6-5-7-12-28)47(70)56-36(22-29-16-18-31(64)19-17-29)45(68)57-37(23-30-24-54-34-14-9-8-13-32(30)34)46(69)55-35(15-10-20-51)44(67)60-40(27(2)63)48(71)61-41/h5-9,11-14,16-19,24,26-27,33,35-41,54,62-64H,10,15,20-23,25,51-52H2,1-4H3,(H2,53,65)(H,55,69)(H,56,70)(H,57,68)(H,58,66)(H,59,72)(H,60,67)(H,61,71)/t26-,27-,33-,35+,36+,37-,38+,39+,40+,41-/m1/s1 PZWWYAHWHHNCHO-FGHAYEPSSA-N 50252861 CHEMBL507214::H-D-Phe-c[Cys-Tyr-DTrp-Orn-Thr-Pen]-Thr-NH2 Mu-type opioid receptor Cavia cutleri 2.8 ChEMBL 10.1021/jm8004702 10.7270/Q20G3K0M 18800771 Ghosh, A; Luo, J; Liu, C; Weltrowska, G; Lemieux, C; Chung, NN; Lu, Y; Schiller, PW National University of Singapore http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252861&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311058 104105583 CHEMBL507214 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50433217 Cc1cc(O)cc(C)c1CCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CCCCNC(=O)NC[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC1=O)C(O)=O InChI=1S/C41H51N7O10/c1-24-18-29(50)19-25(2)30(24)15-16-35(51)45-32(21-27-11-13-28(49)14-12-27)38(54)47-31-10-6-7-17-42-41(58)44-22-34(40(56)57)48-39(55)33(20-26-8-4-3-5-9-26)46-36(52)23-43-37(31)53/h3-5,8-9,11-14,18-19,31-34,49-50H,6-7,10,15-17,20-23H2,1-2H3,(H,43,53)(H,45,51)(H,46,52)(H,47,54)(H,48,55)(H,56,57)(H2,42,44,58)/t31-,32+,33+,34+/m1/s1 XDCADTGFFRTDDH-WNQXLSPZSA-N 50252862 (5S,8S,14R)-8-Benzyl-14-[(S)-2-[3-(4-hydroxy-2,6-dimethyl-phenyl)-propionylamino]-3-(4-hydroxy-phenyl)-propionylamino]-2,7,10,13-tetraoxo-1,3,6,9,12pentaaza-cyclooctadecane-5-carboxylic acid::CHEMBL449801 Mu-type opioid receptor Cavia cutleri 15.5 ChEMBL 10.1021/jm8004702 10.7270/Q20G3K0M 18800771 Ghosh, A; Luo, J; Liu, C; Weltrowska, G; Lemieux, C; Chung, NN; Lu, Y; Schiller, PW National University of Singapore http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252862&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44568842 104105584 CHEMBL449801 ZINC95615167 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50433219 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(N)=O InChI=1S/C40H44N6O5/c1-23-16-29(47)17-24(2)31(23)21-32(41)40(51)46-15-7-12-36(46)39(50)45-35(20-28-22-43-33-11-6-5-10-30(28)33)38(49)44-34(37(42)48)19-25-13-14-26-8-3-4-9-27(26)18-25/h3-6,8-11,13-14,16-18,22,32,34-36,43,47H,7,12,15,19-21,41H2,1-2H3,(H2,42,48)(H,44,49)(H,45,50)/t32-,34+,35-,36+/m0/s1 RVBUBWGVXJZPJO-GIFUDOJISA-N 50252863 CHEMBL507442::antanal 1 Mu-type opioid receptor Cavia cutleri 2.38 ChEMBL 10.1021/jm8004702 10.7270/Q20G3K0M 18800771 Ghosh, A; Luo, J; Liu, C; Weltrowska, G; Lemieux, C; Chung, NN; Lu, Y; Schiller, PW National University of Singapore http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252863&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44568843 104105585 CHEMBL507442 ZINC49898806 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50433221 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(N)=O InChI=1S/C38H43N5O5/c1-23-17-29(44)18-24(2)30(23)22-31(39)38(48)43-16-8-13-34(43)37(47)42-33(20-25-9-4-3-5-10-25)36(46)41-32(35(40)45)21-26-14-15-27-11-6-7-12-28(27)19-26/h3-7,9-12,14-15,17-19,31-34,44H,8,13,16,20-22,39H2,1-2H3,(H2,40,45)(H,41,46)(H,42,47)/t31-,32+,33-,34+/m0/s1 XQWLHPWPDQSALN-GJZXTFMBSA-N 50252864 CHEMBL454035::antanal 2 Mu-type opioid receptor Cavia cutleri 1.52 ChEMBL 10.1021/jm8004702 10.7270/Q20G3K0M 18800771 Ghosh, A; Luo, J; Liu, C; Weltrowska, G; Lemieux, C; Chung, NN; Lu, Y; Schiller, PW National University of Singapore http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252864&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44568844 104105586 CHEMBL454035 ZINC49841321 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50434890 CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C59H69F6N9O10S/c1-33(2)23-46(53(79)73-48(28-38-30-67-44-14-9-8-13-42(38)44)57(83)84-32-37-24-39(58(60,61)62)29-40(25-37)59(63,64)65)72-55(81)49-15-10-21-74(49)56(82)45(20-22-85-4)71-54(80)47(27-35-11-6-5-7-12-35)70-50(76)31-68-51(77)34(3)69-52(78)43(66)26-36-16-18-41(75)19-17-36/h5-9,11-14,16-19,24-25,29-30,33-34,43,45-49,67,75H,10,15,20-23,26-28,31-32,66H2,1-4H3,(H,68,77)(H,69,78)(H,70,76)(H,71,80)(H,72,81)(H,73,79)/t34-,43+,45+,46+,47+,48+,49+/m1/s1 TWBCIHKYFTWYCV-WXYSSXJFSA-N 21021 Bifunctional Peptide Ligand, 5 (TY005)::CHEMBL389652::H-Tyr-D-Ala-Gly-Phe-Met-Pro-Leu-Trp-O-3,5-Bzl(CF3)2::[3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanamido]-4-(methylsulfanyl)butanoyl]pyrrolidin-2-yl]formamido}-4-methylpentanamido]-3-(1H-indol-3-yl)propanoate Mu-type opioid receptor Cavia cutleri 360 ChEMBL 10.1021/jm800389v 10.7270/Q26T0MF1 18821747 Yamamoto, T; Nair, P; Jacobsen, NE; Davis, P; Ma, SW; Navratilova, E; Moye, S; Lai, J; Yamamura, HI; Vanderah, TW; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21021&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16737673 49689094 CHEMBL389652 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50434894 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C46H56N10O10/c1-27(51-43(63)35(47)21-31-13-17-33(57)18-14-31)41(61)49-25-39(59)53-37(23-29-9-5-3-6-10-29)45(65)55-56-46(66)38(24-30-11-7-4-8-12-30)54-40(60)26-50-42(62)28(2)52-44(64)36(48)22-32-15-19-34(58)20-16-32/h3-20,27-28,35-38,57-58H,21-26,47-48H2,1-2H3,(H,49,61)(H,50,62)(H,51,63)(H,52,64)(H,53,59)(H,54,60)(H,55,65)(H,56,66)/t27-,28-,35+,36+,37+,38+/m1/s1 DESSEGDLRYOPTJ-VRANXALZSA-N 21014 (2S)-2-amino-N-[(1R)-1-[({[(1S)-1-{N'-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanoyl]hydrazinecarbonyl}-2-phenylethyl]carbamoyl}methyl)carbamoyl]ethyl]-3-(4-hydroxyphenyl)propanamide::(Tyr-Ala-Gly-Phe-NH2)2::Biphalin::CHEMBL200199::bis(Tyr-Ala-Gly-PheNH2)hydrazide::enkephalin dimer Mu-type opioid receptor Cavia cutleri 8.8 ChEMBL 10.1021/jm800389v 10.7270/Q26T0MF1 18821747 Yamamoto, T; Nair, P; Jacobsen, NE; Davis, P; Ma, SW; Navratilova, E; Moye, S; Lai, J; Yamamura, HI; Vanderah, TW; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21014&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5487663 49689087 CHEMBL200199 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50434895 CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1ccccc1 InChI=1S/C57H72N10O9S/c1-35(2)28-46(54(73)65-48(53(72)60-32-39-16-9-6-10-17-39)31-40-33-59-44-19-12-11-18-42(40)44)66-56(75)49-20-13-26-67(49)57(76)45(25-27-77-4)64-55(74)47(30-37-14-7-5-8-15-37)63-50(69)34-61-51(70)36(3)62-52(71)43(58)29-38-21-23-41(68)24-22-38/h5-12,14-19,21-24,33,35-36,43,45-49,59,68H,13,20,25-32,34,58H2,1-4H3,(H,60,72)(H,61,70)(H,62,71)(H,63,69)(H,64,74)(H,65,73)(H,66,75)/t36-,43+,45+,46+,47+,48+,49+/m1/s1 VUSRUVIDWSRKBU-POSUKJBFSA-N 50264407 CHEMBL448998::Tyr-D-Ala-Gly-Phe-Met-Pro-Leu-Trp-NH-Bzl Mu-type opioid receptor Cavia cutleri 61 ChEMBL 10.1021/jm800389v 10.7270/Q26T0MF1 18821747 Yamamoto, T; Nair, P; Jacobsen, NE; Davis, P; Ma, SW; Navratilova, E; Moye, S; Lai, J; Yamamura, HI; Vanderah, TW; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264407 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264407&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25129135 104112430 CHEMBL448998 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50434896 CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C59H70F6N10O9S/c1-33(2)23-46(54(81)73-48(28-38-31-67-44-14-9-8-13-42(38)44)53(80)68-30-37-24-39(58(60,61)62)29-40(25-37)59(63,64)65)74-56(83)49-15-10-21-75(49)57(84)45(20-22-85-4)72-55(82)47(27-35-11-6-5-7-12-35)71-50(77)32-69-51(78)34(3)70-52(79)43(66)26-36-16-18-41(76)19-17-36/h5-9,11-14,16-19,24-25,29,31,33-34,43,45-49,67,76H,10,15,20-23,26-28,30,32,66H2,1-4H3,(H,68,80)(H,69,78)(H,70,79)(H,71,77)(H,72,82)(H,73,81)(H,74,83)/t34-,43+,45+,46+,47+,48+,49+/m1/s1 UTXLSPLKQGPIPL-WXYSSXJFSA-N 50264406 (S)-1-((2S,5S,11R,14S)-14-amino-5-benzyl-15-(4-hydroxyphenyl)-11-methyl-2-(2-(methylthio)ethyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane)-N-((S)-1-((S)-1-(3,5-bis(trifluoromethyl)benzylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-4-methyl-1-oxopentan-2-yl)pyrrolidine-2-carboxamide::CHEMBL507340::H-Tyr-D-Ala-Gly-Phe-Met-Pro-Leu-Trp-NH-[3',5'-(CF3)2Bzl]::Tyr-D-Ala-Gly-Phe-Met-Pro-Leu-Trp-NH-3,5-Bzl(CF 3) 2 Mu-type opioid receptor Cavia cutleri 490 ChEMBL 10.1021/jm800389v 10.7270/Q26T0MF1 18821747 Yamamoto, T; Nair, P; Jacobsen, NE; Davis, P; Ma, SW; Navratilova, E; Moye, S; Lai, J; Yamamura, HI; Vanderah, TW; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264406 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264406&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25129133 104112429 CHEMBL507340 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50434917 COC(=O)N1CCN([C@H]2[C@@H](CCC[C@H]12)N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C22H29Cl2N3O3/c1-30-22(29)26-11-12-27(20(28)14-15-7-8-16(23)17(24)13-15)21-18(5-4-6-19(21)26)25-9-2-3-10-25/h7-8,13,18-19,21H,2-6,9-12,14H2,1H3/t18-,19+,21+/m1/s1 PAVYSOUZQLFNIW-DYXWJJEUSA-N 50130758 CHEMBL3634395 Mu-type opioid receptor Cavia cutleri 309 ChEMBL 10.1016/j.bmcl.2015.09.040 10.7270/Q2CV4KJC 26411794 Molenveld, P; Bouzanne des Mazery, R; Sterk, GJ; Storcken, RP; Autar, R; van Oss, B; van der Haas, RN; Fröhlich, R; Schepmann, D; Wünsch, B; Soeberdt, M Mercachem http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130758 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130758&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 117710400 321903190 CHEMBL3634395 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50434918 COC(=O)N1CCN([C@H]2[C@H](CCC[C@H]12)N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C22H29Cl2N3O3/c1-30-22(29)26-11-12-27(20(28)14-15-7-8-16(23)17(24)13-15)21-18(5-4-6-19(21)26)25-9-2-3-10-25/h7-8,13,18-19,21H,2-6,9-12,14H2,1H3/t18-,19-,21-/m0/s1 PAVYSOUZQLFNIW-ZJOUEHCJSA-N 50130754 CHEMBL3634397 Mu-type opioid receptor Cavia cutleri 343 ChEMBL 10.1016/j.bmcl.2015.09.040 10.7270/Q2CV4KJC 26411794 Molenveld, P; Bouzanne des Mazery, R; Sterk, GJ; Storcken, RP; Autar, R; van Oss, B; van der Haas, RN; Fröhlich, R; Schepmann, D; Wünsch, B; Soeberdt, M Mercachem http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130754&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 117710481 321903186 CHEMBL3634397 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50434919 COC(=O)N1CCN([C@@H]2[C@@H](CCC[C@@H]12)N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C22H29Cl2N3O3/c1-30-22(29)26-11-12-27(20(28)14-15-7-8-16(23)17(24)13-15)21-18(5-4-6-19(21)26)25-9-2-3-10-25/h7-8,13,18-19,21H,2-6,9-12,14H2,1H3/t18-,19-,21-/m1/s1 PAVYSOUZQLFNIW-SFHLNBCPSA-N 50130755 CHEMBL3634398 Mu-type opioid receptor Cavia cutleri 118 ChEMBL 10.1016/j.bmcl.2015.09.040 10.7270/Q2CV4KJC 26411794 Molenveld, P; Bouzanne des Mazery, R; Sterk, GJ; Storcken, RP; Autar, R; van Oss, B; van der Haas, RN; Fröhlich, R; Schepmann, D; Wünsch, B; Soeberdt, M Mercachem http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130755&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 121308702 321903187 CHEMBL3634398 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50434920 COC(=O)N1CCN([C@H]2[C@@H](CCC[C@@H]12)N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C22H29Cl2N3O3/c1-30-22(29)26-11-12-27(20(28)14-15-7-8-16(23)17(24)13-15)21-18(5-4-6-19(21)26)25-9-2-3-10-25/h7-8,13,18-19,21H,2-6,9-12,14H2,1H3/t18-,19-,21+/m1/s1 PAVYSOUZQLFNIW-SBHAEUEKSA-N 50130756 CHEMBL3634515 Mu-type opioid receptor Cavia cutleri 113 ChEMBL 10.1016/j.bmcl.2015.09.040 10.7270/Q2CV4KJC 26411794 Molenveld, P; Bouzanne des Mazery, R; Sterk, GJ; Storcken, RP; Autar, R; van Oss, B; van der Haas, RN; Fröhlich, R; Schepmann, D; Wünsch, B; Soeberdt, M Mercachem http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130756 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130756&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 86581710 321903188 CHEMBL3634515 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50434921 COC(=O)N1CCN([C@H]2[C@@H](CCC[C@@H]12)N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C22H29Cl2N3O3/c1-30-22(29)26-11-12-27(20(28)14-15-7-8-16(23)17(24)13-15)21-18(5-4-6-19(21)26)25-9-2-3-10-25/h7-8,13,18-19,21H,2-6,9-12,14H2,1H3/t18-,19-,21+/m1/s1 PAVYSOUZQLFNIW-SBHAEUEKSA-N 50130756 CHEMBL3634515 Mu-type opioid receptor Cavia cutleri 113 ChEMBL 10.1016/j.bmcl.2015.09.040 10.7270/Q2CV4KJC 26411794 Molenveld, P; Bouzanne des Mazery, R; Sterk, GJ; Storcken, RP; Autar, R; van Oss, B; van der Haas, RN; Fröhlich, R; Schepmann, D; Wünsch, B; Soeberdt, M Mercachem http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130756 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130756&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 86581710 321903188 CHEMBL3634515 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50434922 COC(=O)N1CCN([C@@H]2[C@H](CCC[C@H]12)N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C22H29Cl2N3O3/c1-30-22(29)26-11-12-27(20(28)14-15-7-8-16(23)17(24)13-15)21-18(5-4-6-19(21)26)25-9-2-3-10-25/h7-8,13,18-19,21H,2-6,9-12,14H2,1H3/t18-,19-,21+/m0/s1 PAVYSOUZQLFNIW-IRFCIJBXSA-N 50130757 CHEMBL3634516 Mu-type opioid receptor Cavia cutleri 43 ChEMBL 10.1016/j.bmcl.2015.09.040 10.7270/Q2CV4KJC 26411794 Molenveld, P; Bouzanne des Mazery, R; Sterk, GJ; Storcken, RP; Autar, R; van Oss, B; van der Haas, RN; Fröhlich, R; Schepmann, D; Wünsch, B; Soeberdt, M Mercachem http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130757 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130757&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 86280667 321903189 CHEMBL3634516 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50434958 CN([C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45)C(=O)\C=C\c1ccoc1 InChI=1S/C28H32N2O5/c1-29(23(32)7-4-18-9-13-34-16-18)20-8-10-28(33)22-14-19-5-6-21(31)25-24(19)27(28,26(20)35-25)11-12-30(22)15-17-2-3-17/h4-7,9,13,16-17,20,22,26,31,33H,2-3,8,10-12,14-15H2,1H3/b7-4+/t20-,22-,26+,27+,28-/m1/s1 XGZZHZMWIXFATA-UEZBDDGYSA-N 50325534 CHEMBL267495::nalfurafine Mu-type opioid receptor Cavia cutleri 0.390000 ChEMBL 10.1016/j.bmcl.2015.09.040 10.7270/Q2CV4KJC 26411794 Molenveld, P; Bouzanne des Mazery, R; Sterk, GJ; Storcken, RP; Autar, R; van Oss, B; van der Haas, RN; Fröhlich, R; Schepmann, D; Wünsch, B; Soeberdt, M Mercachem http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325534&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search IVB 7YIT 6445230 117646855 CHEMBL267495 1651 ZINC04393014 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50434959 Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1 UZHSEJADLWPNLE-GRGSLBFTSA-N 50000788 (morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(naloxone) 4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::(naloxone)4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::(naloxone)4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one (naloxone)::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one( Naloxone)::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(Naxolone)::4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(naloxone)C2H2O4::Analog of 14-(Arylhydroxyamino)codeinone::NALOXONE::NARCAN::SUBOXONE::[17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydroxymorphinan-6-one Mu-type opioid receptor Cavia cutleri 2.1 ChEMBL 10.1016/j.bmcl.2015.09.040 10.7270/Q2CV4KJC 26411794 Molenveld, P; Bouzanne des Mazery, R; Sterk, GJ; Storcken, RP; Autar, R; van Oss, B; van der Haas, RN; Fröhlich, R; Schepmann, D; Wünsch, B; Soeberdt, M Mercachem http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000788&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5284596 103915330 7459 DB01183 1676 C07252 ZINC00389747 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50434960 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 3.9 ChEMBL 10.1016/j.bmcl.2015.09.040 10.7270/Q2CV4KJC 26411794 Molenveld, P; Bouzanne des Mazery, R; Sterk, GJ; Storcken, RP; Autar, R; van Oss, B; van der Haas, RN; Fröhlich, R; Schepmann, D; Wünsch, B; Soeberdt, M Mercachem http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50460774 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)NCCN(CC1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1ccc(O)cc1)[C@@H](Cc1ccccc1)C(=O)NC(CC1CCCCC1)C(O)=O InChI=1S/C71H97N13O10/c1-45-35-55(86)36-46(2)56(45)42-57(73)64(87)79-60(26-16-32-78-71(75)76)66(89)81-61(38-47-17-6-3-7-18-47)67(90)80-59(25-14-15-31-72)65(88)77-33-34-83(63(40-49-21-10-5-11-22-49)68(91)82-62(70(93)94)39-48-19-8-4-9-20-48)44-53-41-51-23-12-13-24-52(51)43-84(53)69(92)58(74)37-50-27-29-54(85)30-28-50/h3,5-7,10-13,17-18,21-24,27-30,35-36,48,53,57-63,85-86H,4,8-9,14-16,19-20,25-26,31-34,37-44,72-74H2,1-2H3,(H,77,88)(H,79,87)(H,80,90)(H,81,89)(H,82,91)(H,93,94)(H4,75,76,78)/t53?,57-,58-,59-,60+,61-,62?,63-/m0/s1 ZYBZKGMEENWLMP-ZVEXDJQDSA-N 50142702 CHEMBL3758231 Mu-type opioid receptor Cavia cutleri 67 ChEMBL 10.1016/j.ejmech.2015.11.028 10.7270/Q2R2137W 26656913 Turnaturi, R; Aricò, G; Ronsisvalle, G; Parenti, C; Pasquinucci, L University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142702&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 127025173 336952808 CHEMBL3758231 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50460787 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@@H]1C(=O)NCC(=O)NCc1ccccc1 InChI=1S/C30H34N4O4/c1-19-12-24(35)13-20(2)25(19)15-26(31)30(38)34-18-23-11-7-6-10-22(23)14-27(34)29(37)33-17-28(36)32-16-21-8-4-3-5-9-21/h3-13,26-27,35H,14-18,31H2,1-2H3,(H,32,36)(H,33,37)/t26-,27+/m0/s1 SYOVEDOWOXNOJG-RRPNLBNLSA-N 50142621 CHEMBL3759292 Mu-type opioid receptor Cavia cutleri 32 ChEMBL 10.1016/j.ejmech.2015.11.028 10.7270/Q2R2137W 26656913 Turnaturi, R; Aricò, G; Ronsisvalle, G; Parenti, C; Pasquinucci, L University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142621 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142621&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9849361 104031986 CHEMBL3759292 ZINC29398986 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50460791 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C32H49N9O5/c1-19-15-22(42)16-20(2)23(19)18-24(34)29(44)40-26(12-8-14-38-32(36)37)30(45)41-27(17-21-9-4-3-5-10-21)31(46)39-25(28(35)43)11-6-7-13-33/h3-5,9-10,15-16,24-27,42H,6-8,11-14,17-18,33-34H2,1-2H3,(H2,35,43)(H,39,46)(H,40,44)(H,41,45)(H4,36,37,38)/t24-,25-,26+,27-/m0/s1 FIAKHZXVLBNZLW-NFGXINMFSA-N 50010483 CHEMBL2181202 Mu-type opioid receptor Cavia cutleri 1.4 ChEMBL 10.1016/j.ejmech.2015.11.028 10.7270/Q2R2137W 26656913 Turnaturi, R; Aricò, G; Ronsisvalle, G; Parenti, C; Pasquinucci, L University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010483&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9809562 242057631 CHEMBL2181202 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50450436 OC(=O)C(F)(F)F.CCC(=O)N(CC1CCCCN1Cc1ccc2[C@H](N)CCCc2c1)c1ccccc1 InChI=1S/C26H35N3O.C2HF3O2/c1-2-26(30)29(22-10-4-3-5-11-22)19-23-12-6-7-16-28(23)18-20-14-15-24-21(17-20)9-8-13-25(24)27;3-2(4,5)1(6)7/h3-5,10-11,14-15,17,23,25H,2,6-9,12-13,16,18-19,27H2,1H3;(H,6,7)/t23?,25-;/m1./s1 LNBZIEPFUNOHBK-FDFNWHSHSA-N 50137508 CHEMBL3752127 Mu-type opioid receptor Cavia cutleri 1005000 ChEMBL 10.1016/j.bmc.2015.11.030 10.7270/Q26H4K8S 26712115 Deekonda, S; Rankin, D; Davis, P; Lai, J; Vanderah, TW; Porecca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137508 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137508&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 127037378 336952009 CHEMBL3752127 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50450437 CCC(=O)N(CC1CCCCN1Cc1ccc2[C@@H](O)CCCc2c1)c1ccccc1 InChI=1S/C26H34N2O2/c1-2-26(30)28(22-10-4-3-5-11-22)19-23-12-6-7-16-27(23)18-20-14-15-24-21(17-20)9-8-13-25(24)29/h3-5,10-11,14-15,17,23,25,29H,2,6-9,12-13,16,18-19H2,1H3/t23?,25-/m0/s1 MSWKQEUSFJHFAI-YNMFNDETSA-N 50137511 CHEMBL3753293 Mu-type opioid receptor Cavia cutleri 74860 ChEMBL 10.1016/j.bmc.2015.11.030 10.7270/Q26H4K8S 26712115 Deekonda, S; Rankin, D; Davis, P; Lai, J; Vanderah, TW; Porecca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137511 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137511&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 127037397 336952012 CHEMBL3753293 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50450438 CCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 InChI=1S/C22H28N2O/c1-2-22(25)24(20-11-7-4-8-12-20)21-14-17-23(18-15-21)16-13-19-9-5-3-6-10-19/h3-12,21H,2,13-18H2,1H3 PJMPHNIQZUBGLI-UHFFFAOYSA-N 50008984 4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-phthalazin-1-one::CHEMBL596::Duragesic-100::Duragesic-12::Duragesic-25::Duragesic-50::Duragesic-75::FENTANYL::FENTANYL CITRATE::FENTANYL-HCl::Fentanyl-100::Fentanyl-12::Fentanyl-25::Fentanyl-50::Fentanyl-75::Fentora::Innovar::Ionsys::N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide::N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide(Fentanyl)::N-(1-phenethylpiperidin-4-yl)-N-phenylpropionamide Mu-type opioid receptor Cavia cutleri 3400 ChEMBL 10.1016/j.bmc.2015.11.030 10.7270/Q26H4K8S 26712115 Deekonda, S; Rankin, D; Davis, P; Lai, J; Vanderah, TW; Porecca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008984&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 7V7 5TZO,8EF5,7U64 3345 103922051 119915 CHEMBL596 DB00813 1626 ZINC02522669 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50460743 C[C@@H]1CN([C@@H](c2cccc(O)c2)c2cccc(c2)C(=O)N(C)c2cccc(F)c2)[C@@H](C)CN1CC=C InChI=1S/C30H34FN3O2/c1-5-15-33-19-22(3)34(20-21(33)2)29(24-10-7-14-28(35)17-24)23-9-6-11-25(16-23)30(36)32(4)27-13-8-12-26(31)18-27/h5-14,16-18,21-22,29,35H,1,15,19-20H2,2-4H3/t21-,22+,29-/m1/s1 LZXRQLIIMYJZDA-UETOGOEVSA-N 50123658 3-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-hydroxy-phenyl)-methyl]-N-(3-fluoro-phenyl)-N-methyl-benzamide::CHEMBL155892 Mu-type opioid receptor Cavia cutleri 1 ChEMBL 10.1016/j.ejmech.2015.11.028 10.7270/Q2R2137W 26656913 Turnaturi, R; Aricò, G; Ronsisvalle, G; Parenti, C; Pasquinucci, L University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123658 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123658&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9826770 104016085 CHEMBL155892 ZINC22444780 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50482081 CN(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)CN1Cc2ccccc2C[C@H](NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C1=O InChI=1S/C39H46F6N8O5/c1-21-11-28(54)12-22(2)29(21)17-30(46)34(56)50-31(9-6-10-49-37(47)48)35(57)51-32-15-24-7-4-5-8-25(24)19-53(36(32)58)20-33(55)52(3)18-23-13-26(38(40,41)42)16-27(14-23)39(43,44)45/h4-5,7-8,11-14,16,30-32,54H,6,9-10,15,17-20,46H2,1-3H3,(H,50,56)(H,51,57)(H4,47,48,49)/t30-,31+,32-/m0/s1 UXNDGPPTVKDIOD-QAXCHELISA-N 50346329 (R)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)-N-((S)-2-(2-((3,5-bis(trifluoromethyl)benzyl)(methyl)amino)-2-oxoethyl)-3-oxo-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-yl)-5-guanidinopentanamide::CHEMBL1782141 Mu-type opioid receptor Cavia cutleri 8.5 ChEMBL 10.1021/acsmedchemlett.5b00359 10.7270/Q2VH5QQJ 26713106 Betti, C; Starnowska, J; Mika, J; Dyniewicz, J; Frankiewicz, L; Novoa, A; Bochynska, M; Keresztes, A; Kosson, P; Makuch, W; Van Duppen, J; Chung, NN; Vanden Broeck, J; Lipkowski, AW; Schiller, PW; Janssens, F; Ceusters, M; Sommen, F; Meert, T; Przewlocka, B; Tourwé, D; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346329 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346329&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 52937467 131349260 CHEMBL1782141 ZINC95548072 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50482082 CN(Cc1ccccc1)C(=O)CCN1Cc2ccccc2C[C@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C1=O InChI=1S/C38H50N8O5/c1-24-18-29(47)19-25(2)30(24)21-31(39)35(49)43-32(14-9-16-42-38(40)41)36(50)44-33-20-27-12-7-8-13-28(27)23-46(37(33)51)17-15-34(48)45(3)22-26-10-5-4-6-11-26/h4-8,10-13,18-19,31-33,47H,9,14-17,20-23,39H2,1-3H3,(H,43,49)(H,44,50)(H4,40,41,42)/t31-,32+,33-/m0/s1 JREBGRHWCUPUKA-DSPMFFIESA-N 50070377 CHEMBL3408519 Mu-type opioid receptor Cavia cutleri 1.9 ChEMBL 10.1021/acsmedchemlett.5b00359 10.7270/Q2VH5QQJ 26713106 Betti, C; Starnowska, J; Mika, J; Dyniewicz, J; Frankiewicz, L; Novoa, A; Bochynska, M; Keresztes, A; Kosson, P; Makuch, W; Van Duppen, J; Chung, NN; Vanden Broeck, J; Lipkowski, AW; Schiller, PW; Janssens, F; Ceusters, M; Sommen, F; Meert, T; Przewlocka, B; Tourwé, D; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070377 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070377&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 118730933 313072393 CHEMBL3408519 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50482083 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C32H49N9O5/c1-19-15-22(42)16-20(2)23(19)18-24(34)29(44)40-26(12-8-14-38-32(36)37)30(45)41-27(17-21-9-4-3-5-10-21)31(46)39-25(28(35)43)11-6-7-13-33/h3-5,9-10,15-16,24-27,42H,6-8,11-14,17-18,33-34H2,1-2H3,(H2,35,43)(H,39,46)(H,40,44)(H,41,45)(H4,36,37,38)/t24-,25-,26+,27-/m0/s1 FIAKHZXVLBNZLW-NFGXINMFSA-N 50010483 CHEMBL2181202 Mu-type opioid receptor Cavia cutleri 1.4 ChEMBL 10.1021/acsmedchemlett.5b00359 10.7270/Q2VH5QQJ 26713106 Betti, C; Starnowska, J; Mika, J; Dyniewicz, J; Frankiewicz, L; Novoa, A; Bochynska, M; Keresztes, A; Kosson, P; Makuch, W; Van Duppen, J; Chung, NN; Vanden Broeck, J; Lipkowski, AW; Schiller, PW; Janssens, F; Ceusters, M; Sommen, F; Meert, T; Przewlocka, B; Tourwé, D; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010483&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9809562 242057631 CHEMBL2181202 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50482084 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N1CCN(CC1)[C@@H]1CCN(C[C@@H]1c1ccccc1)C(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C56H71F6N11O6/c1-34-26-41(74)27-35(2)42(34)32-44(64)49(75)68-45(17-11-20-67-54(65)66)50(76)70-47(28-36-12-5-3-6-13-36)51(77)69-46(16-9-10-19-63)53(79)72-24-22-71(23-25-72)48-18-21-73(33-43(48)37-14-7-4-8-15-37)52(78)38-29-39(55(57,58)59)31-40(30-38)56(60,61)62/h3-8,12-15,26-27,29-31,43-48,74H,9-11,16-25,28,32-33,63-64H2,1-2H3,(H,68,75)(H,69,77)(H,70,76)(H4,65,66,67)/t43-,44+,45-,46+,47+,48-/m1/s1 WCJDWNUHDMSTQS-QEHHYHKYSA-N 50155774 CHEMBL3780776 Mu-type opioid receptor Cavia cutleri 137 ChEMBL 10.1021/acsmedchemlett.5b00359 10.7270/Q2VH5QQJ 26713106 Betti, C; Starnowska, J; Mika, J; Dyniewicz, J; Frankiewicz, L; Novoa, A; Bochynska, M; Keresztes, A; Kosson, P; Makuch, W; Van Duppen, J; Chung, NN; Vanden Broeck, J; Lipkowski, AW; Schiller, PW; Janssens, F; Ceusters, M; Sommen, F; Meert, T; Przewlocka, B; Tourwé, D; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50155774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50155774&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 127032533 340133670 CHEMBL3780776 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50482085 CN([C@@H]1CCN(C[C@@H]1c1ccccc1)C(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C InChI=1S/C53H66F6N10O6/c1-31-23-38(70)24-32(2)39(31)29-41(61)46(71)65-42(18-12-21-64-51(62)63)47(72)67-44(25-33-13-6-4-7-14-33)48(73)66-43(17-10-11-20-60)50(75)68(3)45-19-22-69(30-40(45)34-15-8-5-9-16-34)49(74)35-26-36(52(54,55)56)28-37(27-35)53(57,58)59/h4-9,13-16,23-24,26-28,40-45,70H,10-12,17-22,25,29-30,60-61H2,1-3H3,(H,65,71)(H,66,73)(H,67,72)(H4,62,63,64)/t40-,41+,42-,43+,44+,45-/m1/s1 JHGJAAPNOIHGDJ-XGUPMAOUSA-N 50155794 CHEMBL3780820 Mu-type opioid receptor Cavia cutleri 70 ChEMBL 10.1021/acsmedchemlett.5b00359 10.7270/Q2VH5QQJ 26713106 Betti, C; Starnowska, J; Mika, J; Dyniewicz, J; Frankiewicz, L; Novoa, A; Bochynska, M; Keresztes, A; Kosson, P; Makuch, W; Van Duppen, J; Chung, NN; Vanden Broeck, J; Lipkowski, AW; Schiller, PW; Janssens, F; Ceusters, M; Sommen, F; Meert, T; Przewlocka, B; Tourwé, D; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50155794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50155794&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 127030411 104043161 CHEMBL3780820 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50482086 CN(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)[C@@H]1CCN(C[C@H]1c1ccccc1)C(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C InChI=1S/C54H68F6N10O6/c1-32-23-39(71)24-33(2)41(32)29-43(62)47(72)66-44(18-12-21-65-52(63)64)48(73)68-46(27-34-13-6-4-7-14-34)49(74)67-45(17-10-11-20-61)51(76)70-22-19-40(42(31-70)36-15-8-5-9-16-36)50(75)69(3)30-35-25-37(53(55,56)57)28-38(26-35)54(58,59)60/h4-9,13-16,23-26,28,40,42-46,71H,10-12,17-22,27,29-31,61-62H2,1-3H3,(H,66,72)(H,67,74)(H,68,73)(H4,63,64,65)/t40-,42+,43+,44-,45+,46+/m1/s1 LYMSQSXUWSVHEJ-AQSQZJRWSA-N 50155795 CHEMBL3780408 Mu-type opioid receptor Cavia cutleri 658 ChEMBL 10.1021/acsmedchemlett.5b00359 10.7270/Q2VH5QQJ 26713106 Betti, C; Starnowska, J; Mika, J; Dyniewicz, J; Frankiewicz, L; Novoa, A; Bochynska, M; Keresztes, A; Kosson, P; Makuch, W; Van Duppen, J; Chung, NN; Vanden Broeck, J; Lipkowski, AW; Schiller, PW; Janssens, F; Ceusters, M; Sommen, F; Meert, T; Przewlocka, B; Tourwé, D; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50155795 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50155795&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 127033167 104043162 CHEMBL3780408 ZINC40538182 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50482087 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)CC(N)=O InChI=1S/C33H51N9O5/c1-20-15-24(43)16-21(2)25(20)19-26(35)30(45)41-27(12-8-14-39-33(37)38)31(46)42-28(17-22-9-4-3-5-10-22)32(47)40-23(18-29(36)44)11-6-7-13-34/h3-5,9-10,15-16,23,26-28,43H,6-8,11-14,17-19,34-35H2,1-2H3,(H2,36,44)(H,40,47)(H,41,45)(H,42,46)(H4,37,38,39)/t23-,26-,27+,28-/m0/s1 DSMPYVZTHHPQKD-HXVUFMGFSA-N 50155796 CHEMBL3781680 Mu-type opioid receptor Cavia cutleri 5.9 ChEMBL 10.1021/acsmedchemlett.5b00359 10.7270/Q2VH5QQJ 26713106 Betti, C; Starnowska, J; Mika, J; Dyniewicz, J; Frankiewicz, L; Novoa, A; Bochynska, M; Keresztes, A; Kosson, P; Makuch, W; Van Duppen, J; Chung, NN; Vanden Broeck, J; Lipkowski, AW; Schiller, PW; Janssens, F; Ceusters, M; Sommen, F; Meert, T; Przewlocka, B; Tourwé, D; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50155796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50155796&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 127030158 104043163 CHEMBL3781680 ZINC36748726 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50482088 CN(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)[C@@H]1CCN(C[C@H]1c1ccccc1)C(=O)C[C@H](CCCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C InChI=1S/C55H70F6N10O6/c1-33-23-41(72)24-34(2)43(33)30-45(63)49(74)68-46(18-12-21-66-53(64)65)50(75)69-47(27-35-13-6-4-7-14-35)51(76)67-40(17-10-11-20-62)29-48(73)71-22-19-42(44(32-71)37-15-8-5-9-16-37)52(77)70(3)31-36-25-38(54(56,57)58)28-39(26-36)55(59,60)61/h4-9,13-16,23-26,28,40,42,44-47,72H,10-12,17-22,27,29-32,62-63H2,1-3H3,(H,67,76)(H,68,74)(H,69,75)(H4,64,65,66)/t40-,42+,44-,45-,46+,47-/m0/s1 VTWPYQOXXLXWJD-OXSQTJFYSA-N 50155797 CHEMBL3780818 Mu-type opioid receptor Cavia cutleri 538 ChEMBL 10.1021/acsmedchemlett.5b00359 10.7270/Q2VH5QQJ 26713106 Betti, C; Starnowska, J; Mika, J; Dyniewicz, J; Frankiewicz, L; Novoa, A; Bochynska, M; Keresztes, A; Kosson, P; Makuch, W; Van Duppen, J; Chung, NN; Vanden Broeck, J; Lipkowski, AW; Schiller, PW; Janssens, F; Ceusters, M; Sommen, F; Meert, T; Przewlocka, B; Tourwé, D; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50155797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50155797&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 127032846 104043164 CHEMBL3780818 ZINC36748722 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50482089 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H]1Cc2ccccc2CN(CCC(=O)N2CCN(CC2)[C@@H]2CCN(C[C@@H]2c2ccccc2)C(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)C1=O InChI=1S/C54H64F6N10O6/c1-32-23-40(71)24-33(2)41(32)29-43(61)48(73)65-44(13-8-16-64-52(62)63)49(74)66-45-27-35-11-6-7-12-36(35)30-69(51(45)76)18-15-47(72)68-21-19-67(20-22-68)46-14-17-70(31-42(46)34-9-4-3-5-10-34)50(75)37-25-38(53(55,56)57)28-39(26-37)54(58,59)60/h3-7,9-12,23-26,28,42-46,71H,8,13-22,27,29-31,61H2,1-2H3,(H,65,73)(H,66,74)(H4,62,63,64)/t42-,43+,44-,45+,46-/m1/s1 IYYPPYLIGSSILC-RQCIJDPDSA-N 50155798 CHEMBL3781519 Mu-type opioid receptor Cavia cutleri 20 ChEMBL 10.1021/acsmedchemlett.5b00359 10.7270/Q2VH5QQJ 26713106 Betti, C; Starnowska, J; Mika, J; Dyniewicz, J; Frankiewicz, L; Novoa, A; Bochynska, M; Keresztes, A; Kosson, P; Makuch, W; Van Duppen, J; Chung, NN; Vanden Broeck, J; Lipkowski, AW; Schiller, PW; Janssens, F; Ceusters, M; Sommen, F; Meert, T; Przewlocka, B; Tourwé, D; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50155798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50155798&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 127033173 104043165 CHEMBL3781519 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50482090 CN([C@@H]1CCN(C[C@@H]1c1ccccc1)C(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)CCN1Cc2ccccc2C[C@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C1=O InChI=1S/C51H59F6N9O6/c1-29-20-37(67)21-30(2)38(29)26-40(58)45(69)62-41(14-9-17-61-49(59)60)46(70)63-42-24-32-12-7-8-13-33(32)27-65(48(42)72)19-16-44(68)64(3)43-15-18-66(28-39(43)31-10-5-4-6-11-31)47(71)34-22-35(50(52,53)54)25-36(23-34)51(55,56)57/h4-8,10-13,20-23,25,39-43,67H,9,14-19,24,26-28,58H2,1-3H3,(H,62,69)(H,63,70)(H4,59,60,61)/t39-,40+,41-,42+,43-/m1/s1 YCXVWJZSWBPGRO-UFRKFLGHSA-N 50155799 CHEMBL3781336 Mu-type opioid receptor Cavia cutleri 13 ChEMBL 10.1021/acsmedchemlett.5b00359 10.7270/Q2VH5QQJ 26713106 Betti, C; Starnowska, J; Mika, J; Dyniewicz, J; Frankiewicz, L; Novoa, A; Bochynska, M; Keresztes, A; Kosson, P; Makuch, W; Van Duppen, J; Chung, NN; Vanden Broeck, J; Lipkowski, AW; Schiller, PW; Janssens, F; Ceusters, M; Sommen, F; Meert, T; Przewlocka, B; Tourwé, D; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50155799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50155799&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 127031644 104043166 CHEMBL3781336 ZINC36748734 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50482091 CN(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)[C@@H]1CCN(C[C@H]1c1ccccc1)C(=O)CCN1Cc2ccccc2C[C@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C1=O InChI=1S/C52H61F6N9O6/c1-30-20-38(68)21-31(2)40(30)26-42(59)46(70)63-43(14-9-17-62-50(60)61)47(71)64-44-24-34-12-7-8-13-35(34)28-67(49(44)73)19-16-45(69)66-18-15-39(41(29-66)33-10-5-4-6-11-33)48(72)65(3)27-32-22-36(51(53,54)55)25-37(23-32)52(56,57)58/h4-8,10-13,20-23,25,39,41-44,68H,9,14-19,24,26-29,59H2,1-3H3,(H,63,70)(H,64,71)(H4,60,61,62)/t39-,41+,42+,43-,44+/m1/s1 MCUGZTRVJVPHRW-CRDWDMSXSA-N 50155800 CHEMBL3780686 Mu-type opioid receptor Cavia cutleri 30 ChEMBL 10.1021/acsmedchemlett.5b00359 10.7270/Q2VH5QQJ 26713106 Betti, C; Starnowska, J; Mika, J; Dyniewicz, J; Frankiewicz, L; Novoa, A; Bochynska, M; Keresztes, A; Kosson, P; Makuch, W; Van Duppen, J; Chung, NN; Vanden Broeck, J; Lipkowski, AW; Schiller, PW; Janssens, F; Ceusters, M; Sommen, F; Meert, T; Przewlocka, B; Tourwé, D; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50155800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50155800&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 127033168 104043167 CHEMBL3780686 ZINC36748730 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50500034 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C45H54N6O7/c1-28-22-34(53)23-29(2)35(28)27-36(46)41(55)49-39(26-32-16-18-33(52)19-17-32)43(57)51-45(20-10-5-11-21-45)44(58)50-38(25-31-14-8-4-9-15-31)42(56)48-37(40(47)54)24-30-12-6-3-7-13-30/h3-4,6-9,12-19,22-23,36-39,52-53H,5,10-11,20-21,24-27,46H2,1-2H3,(H2,47,54)(H,48,56)(H,49,55)(H,50,58)(H,51,57)/t36-,37-,38-,39-/m0/s1 VGOMXJZWUGBMKL-GTKRZRNESA-N 50292220 1-[2-[(S)-(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionylamino]-3-(4-hydroxy-phenyl)-propionylamino]-cyclohexanecarboxylic acid [(S)-1-(1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL183278 Mu-type opioid receptor Cavia cutleri 0.071 ChEMBL 10.1016/j.bmcl.2004.11.040 10.7270/Q2FB52FN 15664820 Fujita, Y; Tsuda, Y; Motoyama, T; Li, T; Miyazaki, A; Yokoi, T; Sasaki, Y; Ambo, A; Niizuma, H; Jinsmaa, Y; Bryant, SD; Lazarus, LH; Okada, Y Kobe Gakuin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292220 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292220&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44391126 104133771 CHEMBL183278 ZINC95606542 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50495024 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C)[C@@H](Cc1ccccc1)C(=O)NCCO InChI=1S/C26H35N5O6/c1-17(30-25(36)21(27)14-19-8-10-20(33)11-9-19)24(35)29-16-23(34)31(2)22(26(37)28-12-13-32)15-18-6-4-3-5-7-18/h3-11,17,21-22,32-33H,12-16,27H2,1-2H3,(H,28,37)(H,29,35)(H,30,36)/t17-,21+,22+/m1/s1 HPZJMUBDEAMBFI-WTNAPCKOSA-N 21015 (2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]-N-methylacetamido}-N-(2-hydroxyethyl)-3-phenylpropanamide::2-Ala-4-MePhe-5-Gly-Enkephalin::CHEMBL38874::D-Ala2-MePhe4-Met(0)5-enkephalin-ol::DAMGO::RX 783006::US11492374, ID 2::[3H]DAMGO::[tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephalin Mu-type opioid receptor Cavia cutleri 158 ChEMBL 10.1016/j.bmc.2016.05.005 10.7270/Q2VH5QR0 27234885 Pasquinucci, L; Turnaturi, R; Aricò, G; Parenti, C; Pallaki, P; Georgoussi, Z; Ronsisvalle, S University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21015&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5462471 49689088 CHEMBL38874 1647 C04080 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50495027 C[C@H]1[C@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCC(=O)Nc1cccc2ccccc12 InChI=1S/C27H30N2O2/c1-18-25-16-20-10-11-21(30)17-23(20)27(18,2)13-15-29(25)14-12-26(31)28-24-9-5-7-19-6-3-4-8-22(19)24/h3-11,17-18,25,30H,12-16H2,1-2H3,(H,28,31)/t18-,25+,27+/m0/s1 ZBEAXZAFQYRZBS-YJIIWGRFSA-N 50168141 CHEMBL3797228 Mu-type opioid receptor Cavia cutleri 50118723 ChEMBL 10.1016/j.bmc.2016.05.005 10.7270/Q2VH5QR0 27234885 Pasquinucci, L; Turnaturi, R; Aricò, G; Parenti, C; Pallaki, P; Georgoussi, Z; Ronsisvalle, S University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168141&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 127046953 341104529 CHEMBL3797228 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50495033 C[C@H]1[C@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCC(=O)Nc1cccc2cnccc12 InChI=1S/C26H29N3O2/c1-17-24-14-18-6-7-20(30)15-22(18)26(17,2)10-13-29(24)12-9-25(31)28-23-5-3-4-19-16-27-11-8-21(19)23/h3-8,11,15-17,24,30H,9-10,12-14H2,1-2H3,(H,28,31)/t17-,24+,26+/m0/s1 JKBQIULERLAVIF-BQVXCWBNSA-N 50168140 CHEMBL3797702 Mu-type opioid receptor Cavia cutleri 19953 ChEMBL 10.1016/j.bmc.2016.05.005 10.7270/Q2VH5QR0 27234885 Pasquinucci, L; Turnaturi, R; Aricò, G; Parenti, C; Pallaki, P; Georgoussi, Z; Ronsisvalle, S University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168140 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168140&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 127046954 341104528 CHEMBL3797702 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50495040 C[C@H]1[C@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCC(=O)Nc1ccccc1 InChI=1S/C23H28N2O2/c1-16-21-14-17-8-9-19(26)15-20(17)23(16,2)11-13-25(21)12-10-22(27)24-18-6-4-3-5-7-18/h3-9,15-16,21,26H,10-14H2,1-2H3,(H,24,27)/t16-,21+,23+/m0/s1 VGNUFLUEYYNYCK-POCHDABASA-N 50142692 CHEMBL3759092 Mu-type opioid receptor Cavia cutleri 794 ChEMBL 10.1016/j.bmc.2016.05.005 10.7270/Q2VH5QR0 27234885 Pasquinucci, L; Turnaturi, R; Aricò, G; Parenti, C; Pallaki, P; Georgoussi, Z; Ronsisvalle, S University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142692 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142692&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 123445395 336952799 CHEMBL3759092 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50498269 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H]1Cc2ccccc2CN(CCC(N)=O)C1=O InChI=1S/C30H42N8O5/c1-17-12-21(39)13-18(2)22(17)15-23(31)27(41)36-24(8-5-10-35-30(33)34)28(42)37-25-14-19-6-3-4-7-20(19)16-38(29(25)43)11-9-26(32)40/h3-4,6-7,12-13,23-25,39H,5,8-11,14-16,31H2,1-2H3,(H2,32,40)(H,36,41)(H,37,42)(H4,33,34,35)/t23-,24+,25-/m0/s1 VBTIGXSUDIFYPI-GVAUOCQISA-N 50070386 CHEMBL3408737 Mu-type opioid receptor Cavia cutleri 0.800000 ChEMBL 10.1021/acs.jmedchem.5b01976 10.7270/Q2T72KC6 27035422 Guillemyn, K; Starnowska, J; Lagard, C; Dyniewicz, J; Rojewska, E; Mika, J; Chung, NN; Utard, V; Kosson, P; Lipkowski, AW; Chevillard, L; Arranz-Gibert, P; Teixidó, M; Megarbane, B; Tourwé, D; Simonin, F; Przewlocka, B; Schiller, PW; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070386 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070386&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 118731120 313072402 CHEMBL3408737 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50498270 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCN1Cc2ccccc2C[C@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C1=O)C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C72H107N21O13/c1-5-40(2)60(68(105)86-52(61(75)98)15-8-9-28-73)92-65(102)55(18-12-31-84-72(80)81)88-66(103)56(35-43-19-23-47(94)24-20-43)90-67(104)57(36-44-21-25-48(95)26-22-44)89-63(100)53(16-10-29-82-70(76)77)85-59(97)27-32-93-39-46-14-7-6-13-45(46)37-58(69(93)106)91-64(101)54(17-11-30-83-71(78)79)87-62(99)51(74)38-50-41(3)33-49(96)34-42(50)4/h6-7,13-14,19-26,33-34,40,51-58,60,94-96H,5,8-12,15-18,27-32,35-39,73-74H2,1-4H3,(H2,75,98)(H,85,97)(H,86,105)(H,87,99)(H,88,103)(H,89,100)(H,90,104)(H,91,101)(H,92,102)(H4,76,77,82)(H4,78,79,83)(H4,80,81,84)/t40-,51-,52-,53-,54+,55-,56-,57-,58-,60-/m0/s1 DBXXUNROIBQTKD-XFQSCKMHSA-N 50173127 CHEMBL3808415 Mu-type opioid receptor Cavia cutleri 6.1 ChEMBL 10.1021/acs.jmedchem.5b01976 10.7270/Q2T72KC6 27035422 Guillemyn, K; Starnowska, J; Lagard, C; Dyniewicz, J; Rojewska, E; Mika, J; Chung, NN; Utard, V; Kosson, P; Lipkowski, AW; Chevillard, L; Arranz-Gibert, P; Teixidó, M; Megarbane, B; Tourwé, D; Simonin, F; Przewlocka, B; Schiller, PW; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50173127 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50173127&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 127044528 346548766 CHEMBL3808415 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50498271 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H]1Cc2ccccc2CN(CCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccc(F)cc2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O)C1=O InChI=1S/C77H105FN24O12/c1-42-33-51(104)34-43(2)53(42)39-54(79)66(107)96-58(17-9-30-91-76(85)86)69(110)101-63-37-46-11-3-4-12-47(46)41-102(73(63)114)32-27-64(105)94-57(16-8-29-90-75(83)84)67(108)98-61(36-45-21-25-50(103)26-22-45)71(112)99-60(35-44-19-23-49(78)24-20-44)70(111)97-59(18-10-31-92-77(87)88)68(109)100-62(38-48-40-93-55-14-6-5-13-52(48)55)72(113)95-56(65(80)106)15-7-28-89-74(81)82/h3-6,11-14,19-26,33-34,40,54,56-63,93,103-104H,7-10,15-18,27-32,35-39,41,79H2,1-2H3,(H2,80,106)(H,94,105)(H,95,113)(H,96,107)(H,97,111)(H,98,108)(H,99,112)(H,100,109)(H,101,110)(H4,81,82,89)(H4,83,84,90)(H4,85,86,91)(H4,87,88,92)/t54-,56-,57-,58+,59-,60-,61-,62-,63-/m0/s1 SWIPQMATHCKNQK-NUPJQHTASA-N 50173128 CHEMBL3808398 Mu-type opioid receptor Cavia cutleri 2.0 ChEMBL 10.1021/acs.jmedchem.5b01976 10.7270/Q2T72KC6 27035422 Guillemyn, K; Starnowska, J; Lagard, C; Dyniewicz, J; Rojewska, E; Mika, J; Chung, NN; Utard, V; Kosson, P; Lipkowski, AW; Chevillard, L; Arranz-Gibert, P; Teixidó, M; Megarbane, B; Tourwé, D; Simonin, F; Przewlocka, B; Schiller, PW; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50173128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50173128&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 127043001 346548767 CHEMBL3808398 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50498272 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H]1Cc2ccccc2CN(CCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2c(C)cc(O)cc2C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O)C1=O InChI=1S/C79H110N24O13/c1-42-31-51(105)32-43(2)54(42)38-56(80)68(109)97-60(19-11-28-92-78(86)87)71(112)102-65-36-47-13-5-6-14-48(47)41-103(75(65)116)30-25-66(107)95-59(18-10-27-91-77(84)85)69(110)99-62(35-46-21-23-50(104)24-22-46)72(113)101-64(39-55-44(3)33-52(106)34-45(55)4)74(115)98-61(20-12-29-93-79(88)89)70(111)100-63(37-49-40-94-57-16-8-7-15-53(49)57)73(114)96-58(67(81)108)17-9-26-90-76(82)83/h5-8,13-16,21-24,31-34,40,56,58-65,94,104-106H,9-12,17-20,25-30,35-39,41,80H2,1-4H3,(H2,81,108)(H,95,107)(H,96,114)(H,97,109)(H,98,115)(H,99,110)(H,100,111)(H,101,113)(H,102,112)(H4,82,83,90)(H4,84,85,91)(H4,86,87,92)(H4,88,89,93)/t56-,58-,59-,60+,61-,62-,63-,64-,65-/m0/s1 COJQNEGKUPBZCD-QEOWSWPTSA-N 50173129 CHEMBL3810104 Mu-type opioid receptor Cavia cutleri 5.5 ChEMBL 10.1021/acs.jmedchem.5b01976 10.7270/Q2T72KC6 27035422 Guillemyn, K; Starnowska, J; Lagard, C; Dyniewicz, J; Rojewska, E; Mika, J; Chung, NN; Utard, V; Kosson, P; Lipkowski, AW; Chevillard, L; Arranz-Gibert, P; Teixidó, M; Megarbane, B; Tourwé, D; Simonin, F; Przewlocka, B; Schiller, PW; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50173129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50173129&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 127043559 346548768 CHEMBL3810104 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50498273 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H]1Cc2ccccc2CN(CCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O)C1=O InChI=1S/C77H106N24O13/c1-42-33-51(104)34-43(2)53(42)39-54(78)66(107)95-58(17-9-30-90-76(84)85)69(110)100-63-37-46-11-3-4-12-47(46)41-101(73(63)114)32-27-64(105)93-57(16-8-29-89-75(82)83)67(108)97-61(36-45-21-25-50(103)26-22-45)71(112)98-60(35-44-19-23-49(102)24-20-44)70(111)96-59(18-10-31-91-77(86)87)68(109)99-62(38-48-40-92-55-14-6-5-13-52(48)55)72(113)94-56(65(79)106)15-7-28-88-74(80)81/h3-6,11-14,19-26,33-34,40,54,56-63,92,102-104H,7-10,15-18,27-32,35-39,41,78H2,1-2H3,(H2,79,106)(H,93,105)(H,94,113)(H,95,107)(H,96,111)(H,97,108)(H,98,112)(H,99,109)(H,100,110)(H4,80,81,88)(H4,82,83,89)(H4,84,85,90)(H4,86,87,91)/t54-,56-,57-,58+,59-,60-,61-,62-,63-/m0/s1 AXKZYCSDBWHWOZ-NUPJQHTASA-N 50173130 CHEMBL3808523 Mu-type opioid receptor Cavia cutleri 3.6 ChEMBL 10.1021/acs.jmedchem.5b01976 10.7270/Q2T72KC6 27035422 Guillemyn, K; Starnowska, J; Lagard, C; Dyniewicz, J; Rojewska, E; Mika, J; Chung, NN; Utard, V; Kosson, P; Lipkowski, AW; Chevillard, L; Arranz-Gibert, P; Teixidó, M; Megarbane, B; Tourwé, D; Simonin, F; Przewlocka, B; Schiller, PW; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50173130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50173130&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 127043364 346548769 CHEMBL3808523 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50510693 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CC=C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C32H35N5O5/c33-25(18-23-13-15-24(38)16-14-23)32(42)37-17-7-12-28(37)31(41)36-27(20-22-10-5-2-6-11-22)30(40)35-26(29(34)39)19-21-8-3-1-4-9-21/h1-16,25-28,38H,17-20,33H2,(H2,34,39)(H,35,40)(H,36,41)/t25-,26-,27-,28-/m0/s1 ALCQOUNQFVEEKI-LJWNLINESA-N 50295262 (S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)-2,5-dihydro-1H-pyrrole-2-carboxamide::CHEMBL557243 Mu-type opioid receptor Cavia cutleri 14000 ChEMBL 10.1016/j.bmcl.2009.06.008 10.7270/Q2ZS2WJX 19560919 Torino, D; Mollica, A; Pinnen, F; Lucente, G; Feliciani, F; Davis, P; Lai, J; Ma, SW; Porreca, F; Hruby, VJ Universit£ di Roma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295262 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295262&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11801160 104136793 CHEMBL557243 ZINC70631567 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50510694 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C33H36N6O5/c34-25(16-21-10-12-23(40)13-11-21)33(44)39-15-14-29(39)32(43)38-28(18-22-19-36-26-9-5-4-8-24(22)26)31(42)37-27(30(35)41)17-20-6-2-1-3-7-20/h1-13,19,25,27-29,36,40H,14-18,34H2,(H2,35,41)(H,37,42)(H,38,43)/t25-,27-,28-,29-/m0/s1 POMDUVDTVRXZAV-AMEOFWRWSA-N 50295263 (S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)azetidine-2-carboxamide::CHEMBL552133 Mu-type opioid receptor Cavia cutleri 7900 ChEMBL 10.1016/j.bmcl.2009.06.008 10.7270/Q2ZS2WJX 19560919 Torino, D; Mollica, A; Pinnen, F; Lucente, G; Feliciani, F; Davis, P; Lai, J; Ma, SW; Porreca, F; Hruby, VJ Universit£ di Roma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295263 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295263&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 45269884 104136794 CHEMBL552133 ZINC70631568 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50510695 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C31H35N5O5/c32-24(17-22-11-13-23(37)14-12-22)31(41)36-16-15-27(36)30(40)35-26(19-21-9-5-2-6-10-21)29(39)34-25(28(33)38)18-20-7-3-1-4-8-20/h1-14,24-27,37H,15-19,32H2,(H2,33,38)(H,34,39)(H,35,40)/t24-,25-,26-,27-/m0/s1 JEWBJGBJGWCFIU-FWEHEUNISA-N 50295264 (S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)azetidine-2-carboxamide::CHEMBL563719 Mu-type opioid receptor Cavia cutleri 6400 ChEMBL 10.1016/j.bmcl.2009.06.008 10.7270/Q2ZS2WJX 19560919 Torino, D; Mollica, A; Pinnen, F; Lucente, G; Feliciani, F; Davis, P; Lai, J; Ma, SW; Porreca, F; Hruby, VJ Universit£ di Roma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295264 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295264&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 45270709 104136795 CHEMBL563719 ZINC70631569 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50510696 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CC(C1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C33H36N6O5/c34-26(14-21-10-12-24(40)13-11-21)33(44)39-18-23(19-39)31(42)38-29(16-22-17-36-27-9-5-4-8-25(22)27)32(43)37-28(30(35)41)15-20-6-2-1-3-7-20/h1-13,17,23,26,28-29,36,40H,14-16,18-19,34H2,(H2,35,41)(H,37,43)(H,38,42)/t26-,28-,29-/m0/s1 UADJBABTBBSBNY-ZXRKZBAXSA-N 50295265 CHEMBL540482::N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)azetidine-3-carboxamide Mu-type opioid receptor Cavia cutleri 140000 ChEMBL 10.1016/j.bmcl.2009.06.008 10.7270/Q2ZS2WJX 19560919 Torino, D; Mollica, A; Pinnen, F; Lucente, G; Feliciani, F; Davis, P; Lai, J; Ma, SW; Porreca, F; Hruby, VJ Universit£ di Roma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295265 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295265&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 45272444 104136796 CHEMBL540482 ZINC58589872 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50510697 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CC(C1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C31H35N5O5/c32-25(15-22-11-13-24(37)14-12-22)31(41)36-18-23(19-36)29(39)35-27(17-21-9-5-2-6-10-21)30(40)34-26(28(33)38)16-20-7-3-1-4-8-20/h1-14,23,25-27,37H,15-19,32H2,(H2,33,38)(H,34,40)(H,35,39)/t25-,26-,27-/m0/s1 CIJYZEUBMNBVJS-QKDODKLFSA-N 50295260 CHEMBL564939::N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)azetidine-3-carboxamide Mu-type opioid receptor Cavia cutleri 1400000 ChEMBL 10.1016/j.bmcl.2009.06.008 10.7270/Q2ZS2WJX 19560919 Torino, D; Mollica, A; Pinnen, F; Lucente, G; Feliciani, F; Davis, P; Lai, J; Ma, SW; Porreca, F; Hruby, VJ Universit£ di Roma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295260 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295260&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 45267293 104136791 CHEMBL564939 ZINC70631566 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50510698 N[C@@H](Cc1ccc(O)cc1)C(=O)NC(=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C30H33N5O5/c1-19(33-29(39)24(31)16-22-12-14-23(36)15-13-22)28(38)35-26(18-21-10-6-3-7-11-21)30(40)34-25(27(32)37)17-20-8-4-2-5-9-20/h2-15,24-26,36H,1,16-18,31H2,(H2,32,37)(H,33,39)(H,34,40)(H,35,38)/t24-,25-,26-/m0/s1 IEKPVCQUFXQDCE-GSDHBNRESA-N 50295261 CHEMBL549770::N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)acrylamide Mu-type opioid receptor Cavia cutleri 170000 ChEMBL 10.1016/j.bmcl.2009.06.008 10.7270/Q2ZS2WJX 19560919 Torino, D; Mollica, A; Pinnen, F; Lucente, G; Feliciani, F; Davis, P; Lai, J; Ma, SW; Porreca, F; Hruby, VJ Universit£ di Roma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295261 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295261&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 45269888 104136792 CHEMBL549770 C16734 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50510699 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C34H38N6O5/c35-26(17-22-12-14-24(41)15-13-22)34(45)40-16-6-11-30(40)33(44)39-29(19-23-20-37-27-10-5-4-9-25(23)27)32(43)38-28(31(36)42)18-21-7-2-1-3-8-21/h1-5,7-10,12-15,20,26,28-30,37,41H,6,11,16-19,35H2,(H2,36,42)(H,38,43)(H,39,44)/t26-,28-,29-,30-/m0/s1 ZEXLJFNSKAHNFH-SYKYGTKKSA-N 50095155 (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide::(S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxamide::1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [1-((S)-(S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide::1-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [1-(1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide::CHEMBL316446::ENDOMORPHIN-1::H-Tyr-Pro-Trp-Phe-NH2::Tyr-Pro-Trp-Phe-NH2::YPWF-NH2::endomorphin -1 Mu-type opioid receptor Cavia cutleri 28000 ChEMBL 10.1016/j.bmcl.2009.06.008 10.7270/Q2ZS2WJX 19560919 Torino, D; Mollica, A; Pinnen, F; Lucente, G; Feliciani, F; Davis, P; Lai, J; Ma, SW; Porreca, F; Hruby, VJ Universit£ di Roma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095155&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311080 103992914 CHEMBL316446 1623 ZINC14951658 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50510700 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C32H37N5O5/c33-25(18-23-13-15-24(38)16-14-23)32(42)37-17-7-12-28(37)31(41)36-27(20-22-10-5-2-6-11-22)30(40)35-26(29(34)39)19-21-8-3-1-4-9-21/h1-6,8-11,13-16,25-28,38H,7,12,17-20,33H2,(H2,34,39)(H,35,40)(H,36,41)/t25-,26-,27-,28-/m0/s1 XIJHWXXXIMEHKW-LJWNLINESA-N 50139013 (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::(S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxamide::1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylicacid[1-((S)-(S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL333357::H-Tyr-Pro-Phe-Phe-NH2::Tyr-Pro-Phe-Phe-NH2::endomorphin-2 Mu-type opioid receptor Cavia cutleri 15000 ChEMBL 10.1016/j.bmcl.2009.06.008 10.7270/Q2ZS2WJX 19560919 Torino, D; Mollica, A; Pinnen, F; Lucente, G; Feliciani, F; Davis, P; Lai, J; Ma, SW; Porreca, F; Hruby, VJ Universit£ di Roma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139013&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311081 104029000 CHEMBL333357 3668 ZINC14951634 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50515425 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)CC1(Cc2ccccc2C1)C4=O)ccc5O InChI=1S/C25H25NO4/c1-26-9-8-24-19-14-6-7-17(27)20(19)30-22(24)21(28)23(13-25(24,29)18(26)10-14)11-15-4-2-3-5-16(15)12-23/h2-7,18,22,27,29H,8-13H2,1H3/t18-,22+,24+,25-/m1/s1 YJWDKWRVFJZBCJ-QVJDATKISA-N 50297170 7-(2'-spiroindanyl)oxymorphone::7-(Spiroindano)Oxymorphone::7-spiroindanyloxymorphone::CHEMBL399708::SIOM::Spiroindanyloxymorphone Mu-type opioid receptor Cavia cutleri 10.6 ChEMBL 10.1016/j.bmc.2009.06.067 10.7270/Q2154H3Q 19620007 Fujii, H; Ogawa, R; Ohata, K; Nemoto, T; Nakajima, M; Hasebe, K; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297170 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297170&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44444966 104138701 CHEMBL399708 ZINC13555461 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50515427 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]4(C[C@]5(C[C@@]34O)Nc3ccccc3C5=O)c2c1 InChI=1S/C26H28N2O3/c29-18-8-7-17-11-22-26(31)15-25(23(30)19-3-1-2-4-21(19)27-25)14-24(26,20(17)12-18)9-10-28(22)13-16-5-6-16/h1-4,7-8,12,16,22,27,29,31H,5-6,9-11,13-15H2/t22-,24-,25-,26-/m1/s1 ZYKAZXLZKNSDFZ-VNSJUHMKSA-N 50297169 (6R)-16-(Cyclopropylmethyl)-3,13b-dihydroxy-Cnormorphinan-6-spiro-20-indolin-30-one::CHEMBL551207 Mu-type opioid receptor Cavia cutleri 0.75 ChEMBL 10.1016/j.bmc.2009.06.067 10.7270/Q2154H3Q 19620007 Fujii, H; Ogawa, R; Ohata, K; Nemoto, T; Nakajima, M; Hasebe, K; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297169 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297169&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 45270179 104138700 CHEMBL551207 ZINC62179121 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50508007 Cc1cc(O)c(C)c(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C33H51N9O5/c1-19-16-28(43)21(3)20(2)23(19)18-24(35)30(45)41-26(13-9-15-39-33(37)38)31(46)42-27(17-22-10-5-4-6-11-22)32(47)40-25(29(36)44)12-7-8-14-34/h4-6,10-11,16,24-27,43H,7-9,12-15,17-18,34-35H2,1-3H3,(H2,36,44)(H,40,47)(H,41,45)(H,42,46)(H4,37,38,39)/t24-,25-,26+,27-/m0/s1 ASZIDYXNKKAYAC-NFGXINMFSA-N 50185755 CHEMBL3823054 Mu-type opioid receptor Cavia cutleri 18 ChEMBL 10.1016/j.bmcl.2016.06.003 10.7270/Q2ZW1NVQ 27301366 Cai, Y; Lu, D; Chen, Z; Ding, Y; Chung, NN; Li, T; Schiller, PW Nanjing Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185755&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 127050727 346550641 CHEMBL3823054 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50508028 CCc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C33H51N9O5/c1-3-22-18-23(43)16-20(2)24(22)19-25(35)30(45)41-27(13-9-15-39-33(37)38)31(46)42-28(17-21-10-5-4-6-11-21)32(47)40-26(29(36)44)12-7-8-14-34/h4-6,10-11,16,18,25-28,43H,3,7-9,12-15,17,19,34-35H2,1-2H3,(H2,36,44)(H,40,47)(H,41,45)(H,42,46)(H4,37,38,39)/t25-,26-,27+,28-/m0/s1 XMQDSJQOQLDSQQ-BPXGVECKSA-N 50185754 CHEMBL3822676 Mu-type opioid receptor Cavia cutleri 14 ChEMBL 10.1016/j.bmcl.2016.06.003 10.7270/Q2ZW1NVQ 27301366 Cai, Y; Lu, D; Chen, Z; Ding, Y; Chung, NN; Li, T; Schiller, PW Nanjing Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185754&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 127053144 346550640 CHEMBL3822676 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50515712 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCC(=O)c1nc2ccccc2[nH]1 InChI=1S/C30H31N5O4/c1-17-11-21(36)12-18(2)22(17)14-23(31)30(39)35-16-20-8-4-3-7-19(20)13-26(35)29(38)32-15-27(37)28-33-24-9-5-6-10-25(24)34-28/h3-12,23,26,36H,13-16,31H2,1-2H3,(H,32,38)(H,33,34)/t23-,26-/m0/s1 VYRRFOXJWMIUHF-OZXSUGGESA-N 50297286 1H-benzo[d]imidazol-2-yl 2-((S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido)acetate::CHEMBL556230 Mu-type opioid receptor Cavia cutleri 26.92 ChEMBL 10.1021/jm900686q 10.7270/Q23X86PB 19642675 Balboni, G; Trapella, C; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297286 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297286&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 45272746 104138817 CHEMBL556230 ZINC43024888 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50515713 C[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)c1nc2ccccc2[nH]1 InChI=1S/C31H33N5O4/c1-17-12-22(37)13-18(2)23(17)15-24(32)31(40)36-16-21-9-5-4-8-20(21)14-27(36)30(39)33-19(3)28(38)29-34-25-10-6-7-11-26(25)35-29/h4-13,19,24,27,37H,14-16,32H2,1-3H3,(H,33,39)(H,34,35)/t19-,24-,27-/m0/s1 OEZKDFBBWQUWLW-SZJUTTIESA-N 50297287 (S)-1H-benzo[d]imidazol-2-yl 2-((S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido)propanoate::CHEMBL551937 Mu-type opioid receptor Cavia cutleri 71.7 ChEMBL 10.1021/jm900686q 10.7270/Q23X86PB 19642675 Balboni, G; Trapella, C; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297287 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297287&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 45271895 104138818 CHEMBL551937 ZINC43023088 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50515714 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)c1nc2ccccc2[nH]1 InChI=1S/C32H33N5O6/c1-17-11-21(38)12-18(2)22(17)14-23(33)32(43)37-16-20-8-4-3-7-19(20)13-27(37)31(42)36-26(15-28(39)40)29(41)30-34-24-9-5-6-10-25(24)35-30/h3-12,23,26-27,38H,13-16,33H2,1-2H3,(H,34,35)(H,36,42)(H,39,40)/t23-,26-,27-/m0/s1 WYLIUTMBTUOERM-YGPDHOBYSA-N 50297288 (S)-4-(1H-benzo[d]imidazol-2-yloxy)-3-((S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido)-4-oxobutanoic acid::CHEMBL540972 Mu-type opioid receptor Cavia cutleri 1724 ChEMBL 10.1021/jm900686q 10.7270/Q23X86PB 19642675 Balboni, G; Trapella, C; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297288 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297288&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 45270192 104138819 CHEMBL540972 ZINC42921479 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50515715 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](CCCCN)C(=O)c1nc2ccccc2[nH]1 InChI=1S/C34H40N6O4/c1-20-15-24(41)16-21(2)25(20)18-26(36)34(44)40-19-23-10-4-3-9-22(23)17-30(40)33(43)39-29(13-7-8-14-35)31(42)32-37-27-11-5-6-12-28(27)38-32/h3-6,9-12,15-16,26,29-30,41H,7-8,13-14,17-19,35-36H2,1-2H3,(H,37,38)(H,39,43)/t26-,29-,30-/m0/s1 MJFVZGPGHHUVND-NSGJQZOKSA-N 50297289 (S)-1H-benzo[d]imidazol-2-yl 6-amino-2-((S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido)hexanoate::CHEMBL538456 Mu-type opioid receptor Cavia cutleri 39.7 ChEMBL 10.1021/jm900686q 10.7270/Q23X86PB 19642675 Balboni, G; Trapella, C; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297289&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 45273690 104138820 CHEMBL538456 ZINC42964085 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50515716 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(=O)c1nc2ccccc2[nH]1 InChI=1S/C42H46N6O6/c1-26-20-31(49)21-27(2)32(26)23-33(43)41(52)48-24-30-15-7-6-14-29(30)22-37(48)40(51)47-36(38(50)39-45-34-16-8-9-17-35(34)46-39)18-10-11-19-44-42(53)54-25-28-12-4-3-5-13-28/h3-9,12-17,20-21,33,36-37,49H,10-11,18-19,22-25,43H2,1-2H3,(H,44,53)(H,45,46)(H,47,51)/t33-,36-,37-/m0/s1 RCRODOVSLLRLGH-WOFUPGFCSA-N 50297290 (S)-1H-benzo[d]imidazol-2-yl 2-((S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido)-6-(benzyloxycarbonylamino)hexanoate::CHEMBL559088 Mu-type opioid receptor Cavia cutleri 375 ChEMBL 10.1021/jm900686q 10.7270/Q23X86PB 19642675 Balboni, G; Trapella, C; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297290&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 45267636 104138821 CHEMBL559088 ZINC96307649 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50515717 CC(=O)NCCCC[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)c1nc2ccccc2[nH]1 InChI=1S/C36H42N6O5/c1-21-16-26(44)17-22(2)27(21)19-28(37)36(47)42-20-25-11-5-4-10-24(25)18-32(42)35(46)41-31(14-8-9-15-38-23(3)43)33(45)34-39-29-12-6-7-13-30(29)40-34/h4-7,10-13,16-17,28,31-32,44H,8-9,14-15,18-20,37H2,1-3H3,(H,38,43)(H,39,40)(H,41,46)/t28-,31-,32-/m0/s1 NCZYIAFSLYVJAE-MHDHXZMLSA-N 50297291 (S)-1H-benzo[d]imidazol-2-yl 6-acetamido-2-((S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido)hexanoate::CHEMBL538457 Mu-type opioid receptor Cavia cutleri 53.9 ChEMBL 10.1021/jm900686q 10.7270/Q23X86PB 19642675 Balboni, G; Trapella, C; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297291 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297291&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 45273691 104138822 CHEMBL538457 ZINC42964101 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50515718 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](Cc1c(C)cc(O)cc1C)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)c1nc2ccccc2[nH]1 InChI=1S/C60H74N12O8/c1-34-25-41(73)26-35(2)43(34)31-45(62)59(80)72-33-40-18-9-8-17-39(40)30-52(72)58(79)71-51(32-44-36(3)27-42(74)28-37(44)4)57(78)69-49(22-14-24-65-60(63)64)55(76)70-50(29-38-15-6-5-7-16-38)56(77)68-48(21-12-13-23-61)53(75)54-66-46-19-10-11-20-47(46)67-54/h5-11,15-20,25-28,45,48-52,73-74H,12-14,21-24,29-33,61-62H2,1-4H3,(H,66,67)(H,68,77)(H,69,78)(H,70,76)(H,71,79)(H4,63,64,65)/t45-,48-,49+,50-,51-,52-/m0/s1 QIKVLLYGCWVAPN-JOSVBSQASA-N 50297292 (3S,6R,9S,12S)-1H-benzo[d]imidazol-2-yl 1-((S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinolin-3-yl)-12-(4-aminobutyl)-9-benzyl-6-(3-guanidinopropyl)-3-(4-hydroxy-2,6-dimethylbenzyl)-1,4,7,10-tetraoxo-2,5,8,11-tetraazatridecan-13-oate::CHEMBL553221 Mu-type opioid receptor Cavia cutleri 1.41 ChEMBL 10.1021/jm900686q 10.7270/Q23X86PB 19642675 Balboni, G; Trapella, C; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297292 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297292&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 45271031 104138823 CHEMBL553221 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50515719 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)c1nc2ccccc2[nH]1 InChI=1S/C60H62N8O8/c1-36-28-44(70)29-37(2)45(36)34-46(61)59(75)68-35-42-19-10-9-18-41(42)33-53(68)58(74)66-51(32-40-23-25-43(69)26-24-40)60(76)67-27-13-22-52(67)57(73)65-50(31-39-16-7-4-8-17-39)56(72)64-49(30-38-14-5-3-6-15-38)54(71)55-62-47-20-11-12-21-48(47)63-55/h3-12,14-21,23-26,28-29,46,49-53,69-70H,13,22,27,30-35,61H2,1-2H3,(H,62,63)(H,64,72)(H,65,73)(H,66,74)/t46-,49-,50-,51-,52-,53-/m0/s1 JVFSODOWYPUPIV-QHDHUYINSA-N 50297293 (S)-1H-benzo[d]imidazol-2-yl 2-((S)-2-((S)-1-((S)-2-((S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido)-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxamido)-3-phenylpropanamido)-3-phenylpropanoate::CHEMBL563304 Mu-type opioid receptor Cavia cutleri 6.9 ChEMBL 10.1021/jm900686q 10.7270/Q23X86PB 19642675 Balboni, G; Trapella, C; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297293&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 45273692 104138824 CHEMBL563304 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50515720 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)c1nc2ccccc2[nH]1 InChI=1S/C37H37N5O4/c1-22-16-27(43)17-23(2)28(22)20-29(38)37(46)42-21-26-13-7-6-12-25(26)19-33(42)36(45)41-32(18-24-10-4-3-5-11-24)34(44)35-39-30-14-8-9-15-31(30)40-35/h3-17,29,32-33,43H,18-21,38H2,1-2H3,(H,39,40)(H,41,45)/t29-,32-,33-/m0/s1 YMUGYNHZXSBYNF-LENAEUCASA-N 50297294 (S)-1H-benzo[d]imidazol-2-yl 2-((S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido)-3-phenylpropanoate::CHEMBL556063 Mu-type opioid receptor Cavia cutleri 273 ChEMBL 10.1021/jm900686q 10.7270/Q23X86PB 19642675 Balboni, G; Trapella, C; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297294 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297294&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 45273693 104138825 CHEMBL556063 ZINC43020638 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50515721 N[C@@H](Cc1ccc(O)cc1)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)c1nc2ccccc2[nH]1 InChI=1S/C35H33N5O4/c36-27(18-23-14-16-26(41)17-15-23)35(44)40-21-25-11-5-4-10-24(25)20-31(40)34(43)39-30(19-22-8-2-1-3-9-22)32(42)33-37-28-12-6-7-13-29(28)38-33/h1-17,27,30-31,41H,18-21,36H2,(H,37,38)(H,39,43)/t27-,30-,31-/m0/s1 RZICAEFRILRWER-NAYUSWPISA-N 50297295 (S)-1H-benzo[d]imidazol-2-yl 2-((S)-2-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido)-3-phenylpropanoate::CHEMBL554625 Mu-type opioid receptor Cavia cutleri 398 ChEMBL 10.1021/jm900686q 10.7270/Q23X86PB 19642675 Balboni, G; Trapella, C; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297295 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297295&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 45269368 104138826 CHEMBL554625 ZINC70631604 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50515722 CC(C)C[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)c1nc2ccccc2[nH]1 InChI=1S/C34H39N5O4/c1-19(2)13-29(31(41)32-36-27-11-7-8-12-28(27)37-32)38-33(42)30-16-22-9-5-6-10-23(22)18-39(30)34(43)26(35)17-25-20(3)14-24(40)15-21(25)4/h5-12,14-15,19,26,29-30,40H,13,16-18,35H2,1-4H3,(H,36,37)(H,38,42)/t26-,29-,30-/m0/s1 PVXUMWNRYYUABJ-NSGJQZOKSA-N 50297296 (S)-1H-benzo[d]imidazol-2-yl 2-((S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido)-4-methylpentanoate::CHEMBL539386 Mu-type opioid receptor Cavia cutleri 23.4 ChEMBL 10.1021/jm900686q 10.7270/Q23X86PB 19642675 Balboni, G; Trapella, C; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297296&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 45267637 104138827 CHEMBL539386 ZINC42921489 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50515723 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](CCCN=C(N)N[N+]([O-])=O)C(=O)c1nc2ccccc2[nH]1 InChI=1S/C34H39N9O6/c1-19-14-23(44)15-20(2)24(19)17-25(35)33(47)42-18-22-9-4-3-8-21(22)16-29(42)32(46)40-28(12-7-13-37-34(36)41-43(48)49)30(45)31-38-26-10-5-6-11-27(26)39-31/h3-6,8-11,14-15,25,28-29,44H,7,12-13,16-18,35H2,1-2H3,(H,38,39)(H,40,46)(H3,36,37,41)/t25-,28-,29-/m0/s1 GWTTXLQUCWNILJ-FMYROPPKSA-N 50297297 (S)-1H-benzo[d]imidazol-2-yl 2-((S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido)-5-(3-nitroguanidino)pentanoate::CHEMBL564083 Mu-type opioid receptor Cavia cutleri 106 ChEMBL 10.1021/jm900686q 10.7270/Q23X86PB 19642675 Balboni, G; Trapella, C; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297297 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297297&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 45269369 104138828 CHEMBL564083 ZINC96307616 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50515724 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)c1nc2ccccc2[nH]1 InChI=1S/C34H40N8O4/c1-19-14-23(43)15-20(2)24(19)17-25(35)33(46)42-18-22-9-4-3-8-21(22)16-29(42)32(45)41-28(12-7-13-38-34(36)37)30(44)31-39-26-10-5-6-11-27(26)40-31/h3-6,8-11,14-15,25,28-29,43H,7,12-13,16-18,35H2,1-2H3,(H,39,40)(H,41,45)(H4,36,37,38)/t25-,28-,29-/m0/s1 GUWAGEJINYNLRX-FMYROPPKSA-N 50297298 (S)-N-((S)-1-(1H-benzo[d]imidazol-2-yl)-5-guanidino-1-oxopentan-2-yl)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::CHEMBL554838 Mu-type opioid receptor Cavia cutleri 10.2 ChEMBL 10.1021/jm900686q 10.7270/Q23X86PB 19642675 Balboni, G; Trapella, C; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297298 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297298&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 45269370 104138829 CHEMBL554838 ZINC70631605 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50515725 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)c1nc2ccccc2[nH]1 InChI=1S/C32H34N6O5/c1-17-11-21(39)12-18(2)22(17)14-23(33)32(43)38-16-20-8-4-3-7-19(20)13-27(38)31(42)37-26(15-28(34)40)29(41)30-35-24-9-5-6-10-25(24)36-30/h3-12,23,26-27,39H,13-16,33H2,1-2H3,(H2,34,40)(H,35,36)(H,37,42)/t23-,26-,27-/m0/s1 FDRMLPZUOYOFRY-YGPDHOBYSA-N 50297299 (S)-1H-benzo[d]imidazol-2-yl 4-amino-2-((S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido)-4-oxobutanoate::CHEMBL538699 Mu-type opioid receptor Cavia cutleri 8.5 ChEMBL 10.1021/jm900686q 10.7270/Q23X86PB 19642675 Balboni, G; Trapella, C; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297299&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 45272749 104138830 CHEMBL538699 ZINC42923858 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50515726 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)c1nc2ccccc2[nH]1 InChI=1S/C39H38N6O4/c1-22-15-27(46)16-23(2)29(22)19-30(40)39(49)45-21-25-10-4-3-9-24(25)18-35(45)38(48)44-34(17-26-20-41-31-12-6-5-11-28(26)31)36(47)37-42-32-13-7-8-14-33(32)43-37/h3-16,20,30,34-35,41,46H,17-19,21,40H2,1-2H3,(H,42,43)(H,44,48)/t30-,34-,35-/m0/s1 NJHBOQUHSQOEQQ-RCTKZWLUSA-N 50297300 (S)-1H-benzo[d]imidazol-2-yl 2-((S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido)-3-(1H-indol-3-yl)propanoate::CHEMBL538384 Mu-type opioid receptor Cavia cutleri 35.4 ChEMBL 10.1021/jm900686q 10.7270/Q23X86PB 19642675 Balboni, G; Trapella, C; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297300 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297300&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 45268509 104138831 CHEMBL538384 ZINC49605626 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50515727 CC(=O)OC[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)c1nc2ccccc2[nH]1 InChI=1S/C33H35N5O6/c1-18-12-23(40)13-19(2)24(18)15-25(34)33(43)38-16-22-9-5-4-8-21(22)14-29(38)32(42)37-28(17-44-20(3)39)30(41)31-35-26-10-6-7-11-27(26)36-31/h4-13,25,28-29,40H,14-17,34H2,1-3H3,(H,35,36)(H,37,42)/t25-,28-,29-/m0/s1 LADAJPWUCQHGHY-FMYROPPKSA-N 50297301 (S)-1H-benzo[d]imidazol-2-yl 3-acetoxy-2-((S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido)propanoate::CHEMBL557346 Mu-type opioid receptor Cavia cutleri 7.84 ChEMBL 10.1021/jm900686q 10.7270/Q23X86PB 19642675 Balboni, G; Trapella, C; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297301 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297301&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 45270193 104138832 CHEMBL557346 ZINC43022682 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50515728 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](CO)C(=O)c1nc2ccccc2[nH]1 InChI=1S/C31H33N5O5/c1-17-11-21(38)12-18(2)22(17)14-23(32)31(41)36-15-20-8-4-3-7-19(20)13-27(36)30(40)35-26(16-37)28(39)29-33-24-9-5-6-10-25(24)34-29/h3-12,23,26-27,37-38H,13-16,32H2,1-2H3,(H,33,34)(H,35,40)/t23-,26-,27-/m0/s1 KJNJRTGUXLNNSC-YGPDHOBYSA-N 50297302 (S)-1H-benzo[d]imidazol-2-yl 2-((S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido)-3-hydroxypropanoate::CHEMBL553461 Mu-type opioid receptor Cavia cutleri 34.9 ChEMBL 10.1021/jm900686q 10.7270/Q23X86PB 19642675 Balboni, G; Trapella, C; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297302 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297302&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 45270194 104138833 CHEMBL553461 ZINC42966218 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50515729 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)c1nc2ccccc2[nH]1 InChI=1S/C33H35N5O6/c1-18-13-22(39)14-19(2)23(18)16-24(34)33(44)38-17-21-8-4-3-7-20(21)15-28(38)32(43)37-27(11-12-29(40)41)30(42)31-35-25-9-5-6-10-26(25)36-31/h3-10,13-14,24,27-28,39H,11-12,15-17,34H2,1-2H3,(H,35,36)(H,37,43)(H,40,41)/t24-,27-,28-/m0/s1 QKQBZZDURLHJMJ-WIRXVTQYSA-N 50297303 (S)-5-(1H-benzo[d]imidazol-2-yloxy)-4-((S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido)-5-oxopentanoic acid::CHEMBL540724 Mu-type opioid receptor Cavia cutleri 494 ChEMBL 10.1021/jm900686q 10.7270/Q23X86PB 19642675 Balboni, G; Trapella, C; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297303 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297303&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 45271032 104138834 CHEMBL540724 ZINC42967006 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50508137 CC(C)c1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C34H53N9O5/c1-20(2)24-18-23(44)16-21(3)25(24)19-26(36)31(46)42-28(13-9-15-40-34(38)39)32(47)43-29(17-22-10-5-4-6-11-22)33(48)41-27(30(37)45)12-7-8-14-35/h4-6,10-11,16,18,20,26-29,44H,7-9,12-15,17,19,35-36H2,1-3H3,(H2,37,45)(H,41,48)(H,42,46)(H,43,47)(H4,38,39,40)/t26-,27-,28+,29-/m0/s1 DUCKWYWYGJQFPA-FKWFRFQNSA-N 50185753 CHEMBL3822702 Mu-type opioid receptor Cavia cutleri 410 ChEMBL 10.1016/j.bmcl.2016.06.003 10.7270/Q2ZW1NVQ 27301366 Cai, Y; Lu, D; Chen, Z; Ding, Y; Chung, NN; Li, T; Schiller, PW Nanjing Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185753 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185753&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 127050728 346550639 CHEMBL3822702 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50508138 CCc1cc(O)cc(CC)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C34H53N9O5/c1-3-22-18-24(44)19-23(4-2)25(22)20-26(36)31(46)42-28(14-10-16-40-34(38)39)32(47)43-29(17-21-11-6-5-7-12-21)33(48)41-27(30(37)45)13-8-9-15-35/h5-7,11-12,18-19,26-29,44H,3-4,8-10,13-17,20,35-36H2,1-2H3,(H2,37,45)(H,41,48)(H,42,46)(H,43,47)(H4,38,39,40)/t26-,27-,28+,29-/m0/s1 OQAPMWFSUGSEEU-FKWFRFQNSA-N 50185752 CHEMBL3822822 Mu-type opioid receptor Cavia cutleri 56 ChEMBL 10.1016/j.bmcl.2016.06.003 10.7270/Q2ZW1NVQ 27301366 Cai, Y; Lu, D; Chen, Z; Ding, Y; Chung, NN; Li, T; Schiller, PW Nanjing Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185752 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185752&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 127050729 346550638 CHEMBL3822822 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50508139 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C32H49N9O5/c1-19-15-22(42)16-20(2)23(19)18-24(34)29(44)40-26(12-8-14-38-32(36)37)30(45)41-27(17-21-9-4-3-5-10-21)31(46)39-25(28(35)43)11-6-7-13-33/h3-5,9-10,15-16,24-27,42H,6-8,11-14,17-18,33-34H2,1-2H3,(H2,35,43)(H,39,46)(H,40,44)(H,41,45)(H4,36,37,38)/t24-,25-,26+,27-/m0/s1 FIAKHZXVLBNZLW-NFGXINMFSA-N 50010483 CHEMBL2181202 Mu-type opioid receptor Cavia cutleri 1.4 ChEMBL 10.1016/j.bmcl.2016.06.003 10.7270/Q2ZW1NVQ 27301366 Cai, Y; Lu, D; Chen, Z; Ding, Y; Chung, NN; Li, T; Schiller, PW Nanjing Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010483&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9809562 242057631 CHEMBL2181202 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50508140 NCCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O InChI=1S/C30H45N9O5/c31-15-5-4-9-23(26(33)41)37-29(44)25(18-19-7-2-1-3-8-19)39-28(43)24(10-6-16-36-30(34)35)38-27(42)22(32)17-20-11-13-21(40)14-12-20/h1-3,7-8,11-14,22-25,40H,4-6,9-10,15-18,31-32H2,(H2,33,41)(H,37,44)(H,38,42)(H,39,43)(H4,34,35,36)/t22-,23-,24+,25-/m0/s1 UEVAHGMTRWGMTB-JBXUNAHCSA-N 50016867 (S)-6-Amino-2-((S)-2-{(R)-2-[(S)-2-amino-3-(4-hydroxy-phenyl)-propionylamino]-5-guanidino-pentanoylamino}-3-phenyl-propionylamino)-hexanoic acid amide::6-amino-2-[1-[1-[1-amino-2-(4-hydroxyphenyl)-(1S)-ethylcarboxamido]-4-amino(imino)methylamino-(1R)-butylcarboxamido]-2-phenyl-(1S)-ethylcarboxamido]-(2S)-hexanamide::CHEMBL60444 Mu-type opioid receptor Cavia cutleri 254 ChEMBL 10.1016/j.bmcl.2016.06.003 10.7270/Q2ZW1NVQ 27301366 Cai, Y; Lu, D; Chen, Z; Ding, Y; Chung, NN; Li, T; Schiller, PW Nanjing Medical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016867&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 122222 103928212 CHEMBL60444 ZINC14951239 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50536279 Cc1c(CC(O)=O)c2ccccc2n1C1CCN(Cc2ccccc2)CC1 InChI=1S/C23H26N2O2/c1-17-21(15-23(26)27)20-9-5-6-10-22(20)25(17)19-11-13-24(14-12-19)16-18-7-3-2-4-8-18/h2-10,19H,11-16H2,1H3,(H,26,27) VBPQQBGACUQLOG-UHFFFAOYSA-N 50300853 CHEMBL568473::[2-Methyl-1-(1-benzyl-piperidin-4-yl)-1H-indol-3-yl]-acetic acid Mu-type opioid receptor Cavia cutleri 5164 ChEMBL 10.1016/j.bmc.2009.05.065 10.7270/Q2X92BCX 19540763 Vardanyan, R; Vijay, G; Nichol, GS; Liu, L; Kumarasinghe, I; Davis, P; Vanderah, T; Porreca, F; Lai, J; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50300853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50300853&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 45484431 104155214 CHEMBL568473 ZINC45260788 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50533179 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O InChI=1S/C39H42N4O6/c1-24-17-30(44)18-25(2)31(24)22-32(40)38(47)43-23-29-16-10-9-15-28(29)21-35(43)37(46)41-33(19-26-11-5-3-6-12-26)36(45)42-34(39(48)49)20-27-13-7-4-8-14-27/h3-18,32-35,44H,19-23,40H2,1-2H3,(H,41,46)(H,42,45)(H,48,49)/t32-,33-,34-,35-/m0/s1 SZIMPGYQGJRODH-BBACVFHCSA-N 50299557 (S)-2-((S)-2-((S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido)-3-phenylpropanamido)-3-phenylpropanoic acid::CHEMBL555206::H-2',6'-dimethyltyrosine-Tic-Phe-Phe-OH Mu-type opioid receptor Cavia cutleri 769 ChEMBL 10.1021/jm9004913 10.7270/Q2S182KK 19827750 Berezowska, I; Chung, NN; Lemieux, C; Wilkes, BC; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50299557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50299557&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 45273695 104141086 CHEMBL555206 ZINC49650018 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50533180 N[C@@H](Cc1ccc(O)cc1)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O InChI=1S/C37H38N4O6/c38-30(19-26-15-17-29(42)18-16-26)36(45)41-23-28-14-8-7-13-27(28)22-33(41)35(44)39-31(20-24-9-3-1-4-10-24)34(43)40-32(37(46)47)21-25-11-5-2-6-12-25/h1-18,30-33,42H,19-23,38H2,(H,39,44)(H,40,43)(H,46,47)/t30-,31-,32-,33-/m0/s1 JYOUATXRHWNDDW-YRCZKMHPSA-N 50068664 2-[2-({(S)-2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-4-methyl-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-3-phenyl-propionylamino]-3-phenyl-propionic acid::CHEMBL191751 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm9004913 10.7270/Q2S182KK 19827750 Berezowska, I; Chung, NN; Lemieux, C; Wilkes, BC; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068664 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068664&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 644210 103962856 CHEMBL191751 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50545284 CCCC[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H](CSSC[C@H](NC(=O)[C@@H]2CCCN2C1=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C57H64F6N10O9S2/c1-2-3-13-42-55(82)73-20-9-15-47(73)54(81)72-46(53(80)70-44(25-35-28-65-41-14-8-7-12-39(35)41)50(77)66-27-34-21-36(56(58,59)60)26-37(22-34)57(61,62)63)31-84-83-30-45(71-49(76)40(64)23-33-16-18-38(74)19-17-33)51(78)67-29-48(75)68-43(52(79)69-42)24-32-10-5-4-6-11-32/h4-8,10-12,14,16-19,21-22,26,28,40,42-47,65,74H,2-3,9,13,15,20,23-25,27,29-31,64H2,1H3,(H,66,77)(H,67,78)(H,68,75)(H,69,79)(H,70,80)(H,71,76)(H,72,81)/t40-,42-,43-,44-,45+,46-,47-/m0/s1 CYKFSGXEZOAASR-RBYRPSCESA-N 50304490 CHEMBL611926::H-Tyr-c[D-Cys-Gly-Phe-Nle-Pro-Cys]-Trp-NH-[3',5'-(CF3)2Bzl] Mu-type opioid receptor Cavia cutleri 1000 ChEMBL 10.1016/j.bmc.2009.08.035 10.7270/Q2CJ8DK5 19762245 Yamamoto, T; Nair, P; Ma, SW; Davis, P; Yamamura, HI; Vanderah, TW; Porreca, F; Lai, J; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50304490 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50304490&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46227362 104158851 CHEMBL611926 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50545285 CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O InChI=1S/C28H38N6O6S/c1-17(32-27(39)21(29)14-19-8-10-20(35)11-9-19)26(38)31-16-24(36)33-23(15-18-6-4-3-5-7-18)28(40)34-22(25(30)37)12-13-41-2/h3-11,17,21-23,35H,12-16,29H2,1-2H3,(H2,30,37)(H,31,38)(H,32,39)(H,33,36)(H,34,40)/t17-,21+,22+,23+/m1/s1 ANZXICRKKYOVMY-SZOBAZRNSA-N 50304493 CHEMBL595972::Tyr-D-Ala-Gly-Phe-Met-NH2::Tyr-DAla-Gly-Phe-Met-NH2 Mu-type opioid receptor Cavia cutleri 45 ChEMBL 10.1016/j.bmc.2009.08.035 10.7270/Q2CJ8DK5 19762245 Yamamoto, T; Nair, P; Ma, SW; Davis, P; Yamamura, HI; Vanderah, TW; Porreca, F; Lai, J; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50304493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50304493&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10371120 104158854 CHEMBL595972 ZINC49757425 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50545286 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C46H56N10O10/c1-27(51-43(63)35(47)21-31-13-17-33(57)18-14-31)41(61)49-25-39(59)53-37(23-29-9-5-3-6-10-29)45(65)55-56-46(66)38(24-30-11-7-4-8-12-30)54-40(60)26-50-42(62)28(2)52-44(64)36(48)22-32-15-19-34(58)20-16-32/h3-20,27-28,35-38,57-58H,21-26,47-48H2,1-2H3,(H,49,61)(H,50,62)(H,51,63)(H,52,64)(H,53,59)(H,54,60)(H,55,65)(H,56,66)/t27-,28-,35+,36+,37+,38+/m1/s1 DESSEGDLRYOPTJ-VRANXALZSA-N 21014 (2S)-2-amino-N-[(1R)-1-[({[(1S)-1-{N'-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanoyl]hydrazinecarbonyl}-2-phenylethyl]carbamoyl}methyl)carbamoyl]ethyl]-3-(4-hydroxyphenyl)propanamide::(Tyr-Ala-Gly-Phe-NH2)2::Biphalin::CHEMBL200199::bis(Tyr-Ala-Gly-PheNH2)hydrazide::enkephalin dimer Mu-type opioid receptor Cavia cutleri 8.8 ChEMBL 10.1016/j.bmc.2009.08.035 10.7270/Q2CJ8DK5 19762245 Yamamoto, T; Nair, P; Ma, SW; Davis, P; Yamamura, HI; Vanderah, TW; Porreca, F; Lai, J; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21014&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5487663 49689087 CHEMBL200199 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50545287 CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H]1CSSC[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@@H](Cc2ccccc2)C(=O)N1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C57H64F6N10O9S2/c1-31(2)19-42(52(79)69-44(24-35-27-65-41-12-7-6-11-39(35)41)50(77)66-26-34-20-36(56(58,59)60)25-37(21-34)57(61,62)63)70-54(81)47-13-8-18-73(47)55(82)46-30-84-83-29-45(71-49(76)40(64)22-33-14-16-38(74)17-15-33)51(78)67-28-48(75)68-43(53(80)72-46)23-32-9-4-3-5-10-32/h3-7,9-12,14-17,20-21,25,27,31,40,42-47,65,74H,8,13,18-19,22-24,26,28-30,64H2,1-2H3,(H,66,77)(H,67,78)(H,68,75)(H,69,79)(H,70,81)(H,71,76)(H,72,80)/t40-,42-,43-,44-,45+,46+,47-/m0/s1 ATLZVWRXMUZKNV-KMWMRXANSA-N 50304491 CHEMBL611925::H-Tyr-c[D-Cys-Gly-Phe-D-Cys]-Pro-Leu-Trp-NH-[3',5'-(CF3)2Bzl] Mu-type opioid receptor Cavia cutleri 280 ChEMBL 10.1016/j.bmc.2009.08.035 10.7270/Q2CJ8DK5 19762245 Yamamoto, T; Nair, P; Ma, SW; Davis, P; Yamamura, HI; Vanderah, TW; Porreca, F; Lai, J; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50304491 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50304491&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46227361 104158852 CHEMBL611925 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50535103 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](CCCN(N=C=S)N=C=S)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(O)=O InChI=1S/C44H52N10O11S2/c45-32(20-28-10-14-30(56)15-11-28)39(59)50-33(8-4-19-54(47-25-66)48-26-67)41(61)51-34(21-27-6-2-1-3-7-27)40(60)46-23-38(58)49-35(22-29-12-16-31(57)17-13-29)43(63)53-18-5-9-37(53)42(62)52-36(24-55)44(64)65/h1-3,6-7,10-17,32-37,55-57H,4-5,8-9,18-24,45H2,(H,46,60)(H,49,58)(H,50,59)(H,51,61)(H,52,62)(H,64,65)/t32-,33+,34-,35-,36-,37-/m0/s1 KAIURMDWXDWNLH-PQVJJDQFSA-N 50300356 (S)-2-((S)-1-((2S,8S,11R,14S)-14-amino-8-benzyl-11-(3-(diisothiocyanatoamino)propyl)-2-(4-hydroxybenzyl)-15-(4-hydroxyphenyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane)pyrrolidine-2-carboxamido)-3-hydroxypropanoic acid::CHEMBL584993 Mu-type opioid receptor Cavia cutleri 2.2 ChEMBL 10.1021/jm9007592 10.7270/Q2K64J5B 19621878 Sinha, B; Cao, Z; Murray, TF; Aldrich, JV The University of Kansas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50300356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50300356&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 45483986 104154717 CHEMBL584993 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50535106 COC(=O)\C=C\C(=O)N[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45 InChI=1S/C25H30N2O6/c1-32-20(30)7-6-19(29)26-16-8-9-25(31)18-12-15-4-5-17(28)22-21(15)24(25,23(16)33-22)10-11-27(18)13-14-2-3-14/h4-7,14,16,18,23,28,31H,2-3,8-13H2,1H3,(H,26,29)/b7-6+/t16-,18-,23+,24+,25-/m1/s1 PQKHESYTSKMWFP-WZJCLRDWSA-N 50247803 Beta-Funeltrexamine::CHEMBL473136::beta-funaltrexamine::methyl (2E)-3-{[(1S,5R,13R,14R,17S)-4-(cyclopropylmethyl)-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10-trien-14-yl]carbamoyl}prop-2-enoate::methyl 3-[4-cyclopropylmethyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-ylcarbamoyl]-(E)-2-propenoate Mu-type opioid receptor Cavia cutleri 2.2 ChEMBL 10.1021/jm9007592 10.7270/Q2K64J5B 19621878 Sinha, B; Cao, Z; Murray, TF; Aldrich, JV The University of Kansas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50247803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50247803&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311018 104102600 CHEMBL473136 1631 C18127 ZINC03995756 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50563925 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCCNC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C InChI=1S/C44H52N6O6/c1-25-15-33(51)16-26(2)35(25)21-37(45)43(55)49-23-31-11-7-5-9-29(31)19-39(49)41(53)47-13-14-48-42(54)40-20-30-10-6-8-12-32(30)24-50(40)44(56)38(46)22-36-27(3)17-34(52)18-28(36)4/h5-12,15-18,37-40,51-52H,13-14,19-24,45-46H2,1-4H3,(H,47,53)(H,48,54)/t37-,38-,39-,40-/m0/s1 PRBXNWSQINCCHE-YKKXUYLKSA-N 50312854 (S,3S,3'S)-N,N'-(ethane-1,2-diyl)bis(2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide)::CHEMBL1076736 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1016/j.bmcl.2010.01.055 10.7270/Q2H995BB 20137938 Ballet, S; Marczak, ED; Feytens, D; Salvadori, S; Sasaki, Y; Abell, AD; Lazarus, LH; Balboni, G; Tourwe, D Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50312854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50312854&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46880888 104147215 CHEMBL1076736 ZINC95538313 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50563926 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H]1Cc2ccccc2CN(CC(=O)NCCNC(=O)CN2Cc3ccccc3C[C@H](NC(=O)[C@@H](N)Cc3c(C)cc(O)cc3C)C2=O)C1=O InChI=1S/C48H58N8O8/c1-27-15-35(57)16-28(2)37(27)21-39(49)45(61)53-41-19-31-9-5-7-11-33(31)23-55(47(41)63)25-43(59)51-13-14-52-44(60)26-56-24-34-12-8-6-10-32(34)20-42(48(56)64)54-46(62)40(50)22-38-29(3)17-36(58)18-30(38)4/h5-12,15-18,39-42,57-58H,13-14,19-26,49-50H2,1-4H3,(H,51,59)(H,52,60)(H,53,61)(H,54,62)/t39-,40-,41-,42-/m0/s1 RADODKJLZRLHCQ-IWWWZYECSA-N 50312855 (2S,2'S)-N,N'-((4S,4'S)-2,2'-(2,2'-(ethane-1,2-diylbis(azanediyl))bis(2-oxoethane-2,1-diyl))bis(3-oxo-2,3,4,5-tetrahydro-1H-benzo[c]azepine-4,2-diyl))bis(2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanamide)::CHEMBL1076737 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1016/j.bmcl.2010.01.055 10.7270/Q2H995BB 20137938 Ballet, S; Marczak, ED; Feytens, D; Salvadori, S; Sasaki, Y; Abell, AD; Lazarus, LH; Balboni, G; Tourwe, D Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50312855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50312855&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46880889 104147216 CHEMBL1076737 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50563927 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCC\C=C\CCNC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C InChI=1S/C48H58N6O6/c1-29-19-37(55)20-30(2)39(29)25-41(49)47(59)53-27-35-15-9-7-13-33(35)23-43(53)45(57)51-17-11-5-6-12-18-52-46(58)44-24-34-14-8-10-16-36(34)28-54(44)48(60)42(50)26-40-31(3)21-38(56)22-32(40)4/h5-10,13-16,19-22,41-44,55-56H,11-12,17-18,23-28,49-50H2,1-4H3,(H,51,57)(H,52,58)/b6-5+/t41-,42-,43-,44-/m0/s1 QUUTWUNCRLZYFR-WDNYOLFRSA-N 50312859 (S,3S,3'S)-N,N'-(hex-3-ene-1,6-diyl)bis(2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide)::CHEMBL1076724 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1016/j.bmcl.2010.01.055 10.7270/Q2H995BB 20137938 Ballet, S; Marczak, ED; Feytens, D; Salvadori, S; Sasaki, Y; Abell, AD; Lazarus, LH; Balboni, G; Tourwe, D Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50312859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50312859&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46880893 104147220 CHEMBL1076724 ZINC95548967 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50563928 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCCN(CCNC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)CCNC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C InChI=1S/C69H84N10O9/c1-40-25-52(80)26-41(2)55(40)34-58(70)67(86)77-37-49-16-10-7-13-46(49)31-61(77)64(83)73-19-22-76(23-20-74-65(84)62-32-47-14-8-11-17-50(47)38-78(62)68(87)59(71)35-56-42(3)27-53(81)28-43(56)4)24-21-75-66(85)63-33-48-15-9-12-18-51(48)39-79(63)69(88)60(72)36-57-44(5)29-54(82)30-45(57)6/h7-18,25-30,58-63,80-82H,19-24,31-39,70-72H2,1-6H3,(H,73,83)(H,74,84)(H,75,85)/t58-,59-,60-,61-,62-,63-/m0/s1 BBPYIFGRDIJHBN-DIGKZBRYSA-N 50312860 (S,S,3S,3'S,3''S)-N,N',N''-(2,2',2''-nitrilotris(ethane-2,1-diyl))tris(2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide)::CHEMBL1076725 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1016/j.bmcl.2010.01.055 10.7270/Q2H995BB 20137938 Ballet, S; Marczak, ED; Feytens, D; Salvadori, S; Sasaki, Y; Abell, AD; Lazarus, LH; Balboni, G; Tourwe, D Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50312860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50312860&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46880894 104147221 CHEMBL1076725 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50563929 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H]1Cc2ccccc2CN(CC(=O)NCCN(CCNC(=O)CN2Cc3ccccc3C[C@H](NC(=O)[C@@H](N)Cc3c(C)cc(O)cc3C)C2=O)CCNC(=O)CN2Cc3ccccc3C[C@H](NC(=O)[C@@H](N)Cc3c(C)cc(O)cc3C)C2=O)C1=O InChI=1S/C75H93N13O12/c1-43-25-55(89)26-44(2)58(43)34-61(76)70(95)82-64-31-49-13-7-10-16-52(49)37-86(73(64)98)40-67(92)79-19-22-85(23-20-80-68(93)41-87-38-53-17-11-8-14-50(53)32-65(74(87)99)83-71(96)62(77)35-59-45(3)27-56(90)28-46(59)4)24-21-81-69(94)42-88-39-54-18-12-9-15-51(54)33-66(75(88)100)84-72(97)63(78)36-60-47(5)29-57(91)30-48(60)6/h7-18,25-30,61-66,89-91H,19-24,31-42,76-78H2,1-6H3,(H,79,92)(H,80,93)(H,81,94)(H,82,95)(H,83,96)(H,84,97)/t61-,62-,63-,64-,65-,66-/m0/s1 PRNBTKYAMOLYOE-SULQXJCYSA-N 50312861 (2S,2'S,2''S)-N,N',N''-((4S,4'S,4''S)-2,2',2''-(2,2',2''-(2,2',2''-nitrilotris(ethane-2,1-diyl)tris(azanediyl))tris(2-oxoethane-2,1-diyl))tris(3-oxo-2,3,4,5-tetrahydro-1H-benzo[c]azepine-4,2-diyl))tris(2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanamide)::CHEMBL1076726 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1016/j.bmcl.2010.01.055 10.7270/Q2H995BB 20137938 Ballet, S; Marczak, ED; Feytens, D; Salvadori, S; Sasaki, Y; Abell, AD; Lazarus, LH; Balboni, G; Tourwe, D Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50312861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50312861&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46880895 104147222 CHEMBL1076726 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50557330 CC(CCN(C)Cc1ccccc1)c1ccc(cc1)-c1ccccc1 InChI=1S/C24H27N/c1-20(17-18-25(2)19-21-9-5-3-6-10-21)22-13-15-24(16-14-22)23-11-7-4-8-12-23/h3-16,20H,17-19H2,1-2H3 NGVZNUKOMGCFRY-UHFFFAOYSA-N 50198062 (R/S)-N-Benzyl-3-(biphenyl-4-yl)-N-methylbutan-1-amine::CHEMBL224151::benzyl-(3-biphenyl-4-yl-butyl)-methyl-amine Mu-type opioid receptor Cavia cutleri 248 ChEMBL 10.1016/j.bmc.2009.12.039 10.7270/Q2PN95S5 20045339 Rossi, D; Urbano, M; Pedrali, A; Serra, M; Zampieri, D; Mamolo, MG; Laggner, C; Zanette, C; Florio, C; Schepmann, D; Wuensch, B; Azzolina, O; Collina, S University of Pavia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50198062 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50198062&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44422358 104079148 CHEMBL224151 ZINC28642410 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50557670 CN(CC1CC1)[C@@H]1Cc2ccc(O)c3O[C@H]4C(=O)CC[C@@]11OCC[C@]41c23 InChI=1S/C21H25NO4/c1-22(11-12-2-3-12)16-10-13-4-5-14(23)18-17(13)20-8-9-25-21(16,20)7-6-15(24)19(20)26-18/h4-5,12,16,19,23H,2-3,6-11H2,1H3/t16-,19+,20+,21-/m1/s1 AFQDTMLOPHOESA-MBPVOVBZSA-N 50310292 CHEMBL604522::KNT-5 Mu-type opioid receptor Cavia cutleri 24 ChEMBL 10.1016/j.bmcl.2009.12.039 10.7270/Q28C9WC0 20056539 Imaide, S; Fujii, H; Watanabe, A; Nemoto, T; Nakajima, M; Nakao, K; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50310292 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50310292&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46232163 104144653 CHEMBL604522 ZINC45389838 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50557672 CN(CC1CC1)[C@@H]1Cc2ccc(O)c3OCC[C@@]4(CC(=O)CC[C@@]14O)c23 InChI=1S/C21H27NO4/c1-22(12-13-2-3-13)17-10-14-4-5-16(24)19-18(14)20(8-9-26-19)11-15(23)6-7-21(17,20)25/h4-5,13,17,24-25H,2-3,6-12H2,1H3/t17-,20-,21-/m1/s1 DNHRXKRQWRVVFT-DUXKGJEZSA-N 50310293 (41R,12R,12aS)-12-((cyclopropylmethyl)(methyl)amino)-8,12a-dihydroxy-4,5,6,11,12,12a-hexahydro-1H-naphtho[1,2-de]chromen-3(2H)-one hydrochloride::CHEMBL598939 Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1016/j.bmcl.2009.12.039 10.7270/Q28C9WC0 20056539 Imaide, S; Fujii, H; Watanabe, A; Nemoto, T; Nakajima, M; Nakao, K; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50310293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50310293&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46232165 104144654 CHEMBL598939 ZINC45365715 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50557674 CC[C@@]12[C@H]3Oc4c1c(C[C@@H](NCC1CC1)[C@]2(O)CCC3=O)ccc4O InChI=1S/C20H25NO4/c1-2-19-16-12-5-6-13(22)17(16)25-18(19)14(23)7-8-20(19,24)15(9-12)21-10-11-3-4-11/h5-6,11,15,18,21-22,24H,2-4,7-10H2,1H3/t15-,18+,19+,20-/m1/s1 UQLNRMGVZGTTCH-XFWGSAIBSA-N 50310294 (2R,2aS,2a1S,5aR)-2-(cyclopropylmethylamino)-2a1-ethyl-2a,7-dihydroxy-2,2a,2a1,3,4,5a-hexahydrophenanthro[4,5-bcd]furan-5(1H)-one hydrochloride::CHEMBL598940 Mu-type opioid receptor Cavia cutleri 26.3 ChEMBL 10.1016/j.bmcl.2009.12.039 10.7270/Q28C9WC0 20056539 Imaide, S; Fujii, H; Watanabe, A; Nemoto, T; Nakajima, M; Nakao, K; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50310294 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50310294&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46232167 104144655 CHEMBL598940 ZINC45365718 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50557678 CN(CC1CC1)[C@@H]1Cc2ccc(O)c3O[C@H]4C(=O)CC[C@]1(O)[C@@]4(C=C)c23 InChI=1S/C21H25NO4/c1-3-20-17-13-6-7-14(23)18(17)26-19(20)15(24)8-9-21(20,25)16(10-13)22(2)11-12-4-5-12/h3,6-7,12,16,19,23,25H,1,4-5,8-11H2,2H3/t16-,19+,20+,21-/m1/s1 UKZYDQRSZAEKER-MBPVOVBZSA-N 50310296 (2R,2aS,2a1S,5aR)-2-((cyclopropylmethyl)(methyl)amino)-2a,7-dihydroxy-2a1-vinyl-2,2a,2a1,3,4,5a-hexahydrophenanthro[4,5-bcd]furan-5(1H)-one hydrochloride::CHEMBL604939 Mu-type opioid receptor Cavia cutleri 26.4 ChEMBL 10.1016/j.bmcl.2009.12.039 10.7270/Q28C9WC0 20056539 Imaide, S; Fujii, H; Watanabe, A; Nemoto, T; Nakajima, M; Nakao, K; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50310296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50310296&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46232171 104144657 CHEMBL604939 ZINC45385945 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50557680 Oc1ccc2C[C@@H](NCC3CC3)[C@]3(O)CCC(=O)[C@@H]4Oc1c2[C@]34C=C InChI=1S/C20H23NO4/c1-2-19-16-12-5-6-13(22)17(16)25-18(19)14(23)7-8-20(19,24)15(9-12)21-10-11-3-4-11/h2,5-6,11,15,18,21-22,24H,1,3-4,7-10H2/t15-,18+,19+,20-/m1/s1 MSLUZRRNVVBCEO-XFWGSAIBSA-N 50310297 (2R,2aS,2a1S,5aR)-2-(cyclopropylmethylamino)-2a,7-dihydroxy-2a1-vinyl-2,2a,2a1,3,4,5a-hexahydrophenanthro[4,5-bcd]furan-5(1H)-one hydrochloride::CHEMBL604733 Mu-type opioid receptor Cavia cutleri 8.6 ChEMBL 10.1016/j.bmcl.2009.12.039 10.7270/Q28C9WC0 20056539 Imaide, S; Fujii, H; Watanabe, A; Nemoto, T; Nakajima, M; Nakao, K; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50310297 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50310297&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46232212 104144658 CHEMBL604733 ZINC45386501 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50557682 CN(CC1CC1)C1Cc2ccc(O)c3O[C@H]4C(=O)CC[C@]1(O)[C@@]4(CCn1ccnn1)c23 InChI=1S/C23H28N4O4/c1-26(13-14-2-3-14)18-12-15-4-5-16(28)20-19(15)22(8-10-27-11-9-24-25-27)21(31-20)17(29)6-7-23(18,22)30/h4-5,9,11,14,18,21,28,30H,2-3,6-8,10,12-13H2,1H3/t18?,21-,22-,23+/m0/s1 HIKDHLZARSHDJX-JMAINCIWSA-N 50310298 (2aS,2a1S,5aR)-2a1-(2-(1H-1,2,3-triazol-1-yl)ethyl)-2-((cyclopropylmethyl)(methyl)amino)-2a,7-dihydroxy-2,2a,2a1,3,4,5a-hexahydrophenanthro[4,5-bcd]furan-5(1H)-one hydrochloride::CHEMBL599533 Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1016/j.bmcl.2009.12.039 10.7270/Q28C9WC0 20056539 Imaide, S; Fujii, H; Watanabe, A; Nemoto, T; Nakajima, M; Nakao, K; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50310298 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50310298&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46232214 104144659 CHEMBL599533 ZINC45374129 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50557676 CC[C@@]12[C@H]3Oc4c1c(C[C@@H](N(C)CC1CC1)[C@]2(O)CCC3=O)ccc4O InChI=1S/C21H27NO4/c1-3-20-17-13-6-7-14(23)18(17)26-19(20)15(24)8-9-21(20,25)16(10-13)22(2)11-12-4-5-12/h6-7,12,16,19,23,25H,3-5,8-11H2,1-2H3/t16-,19+,20+,21-/m1/s1 AFWQBADFAUBXEN-MBPVOVBZSA-N 50310295 (2R,2aS,2a1S,5aR)-2-((cyclopropylmethyl)(methyl)amino)-2a1-ethyl-2a,7-dihydroxy-2,2a,2a1,3,4,5a-hexahydrophenanthro[4,5-bcd]furan-5(1H)-one hydrochloride::CHEMBL599323 Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1016/j.bmcl.2009.12.039 10.7270/Q28C9WC0 20056539 Imaide, S; Fujii, H; Watanabe, A; Nemoto, T; Nakajima, M; Nakao, K; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50310295 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50310295&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46232169 104144656 CHEMBL599323 ZINC45357602 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50580922 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C32H37N5O5/c33-25(18-23-13-15-24(38)16-14-23)32(42)37-17-7-12-28(37)31(41)36-27(20-22-10-5-2-6-11-22)30(40)35-26(29(34)39)19-21-8-3-1-4-9-21/h1-6,8-11,13-16,25-28,38H,7,12,17-20,33H2,(H2,34,39)(H,35,40)(H,36,41)/t25-,26-,27-,28-/m0/s1 XIJHWXXXIMEHKW-LJWNLINESA-N 50139013 (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::(S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxamide::1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylicacid[1-((S)-(S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL333357::H-Tyr-Pro-Phe-Phe-NH2::Tyr-Pro-Phe-Phe-NH2::endomorphin-2 Mu-type opioid receptor Cavia cutleri 15 ChEMBL 10.1021/jm1001343 10.7270/Q23F4PTK 20476738 Torino, D; Mollica, A; Pinnen, F; Feliciani, F; Lucente, G; Fabrizi, G; Portalone, G; Davis, P; Lai, J; Ma, SW; Porreca, F; Hruby, VJ Universit£ di Roma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139013&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311081 104029000 CHEMBL333357 3668 ZINC14951634 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50580923 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N\C(=C/c1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C32H35N5O5/c33-25(18-23-13-15-24(38)16-14-23)32(42)37-17-7-12-28(37)31(41)36-27(20-22-10-5-2-6-11-22)30(40)35-26(29(34)39)19-21-8-3-1-4-9-21/h1-6,8-11,13-16,20,25-26,28,38H,7,12,17-19,33H2,(H2,34,39)(H,35,40)(H,36,41)/b27-20-/t25-,26-,28-/m0/s1 WPBFUFSZAPUNPD-LTYLLROCSA-N 50320024 (S)-N-(3-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-3-oxo-1-phenylprop-1-en-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxamide::CHEMBL1084185 Mu-type opioid receptor Cavia cutleri 170 ChEMBL 10.1021/jm1001343 10.7270/Q23F4PTK 20476738 Torino, D; Mollica, A; Pinnen, F; Feliciani, F; Lucente, G; Fabrizi, G; Portalone, G; Davis, P; Lai, J; Ma, SW; Porreca, F; Hruby, VJ Universit£ di Roma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50320024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50320024&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46831096 104141553 CHEMBL1084185 ZINC53227602 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50580924 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N\C(=C/c1ccccc1)C(N)=O InChI=1S/C32H35N5O5/c33-25(18-23-13-15-24(38)16-14-23)32(42)37-17-7-12-28(37)31(41)36-27(20-22-10-5-2-6-11-22)30(40)35-26(29(34)39)19-21-8-3-1-4-9-21/h1-6,8-11,13-16,19,25,27-28,38H,7,12,17-18,20,33H2,(H2,34,39)(H,35,40)(H,36,41)/b26-19-/t25-,27-,28-/m0/s1 FXSPYKUYSUZEFV-LCYFZASWSA-N 50320022 (S)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)-N-((S)-1-(3-amino-3-oxo-1-phenylprop-1-en-2-ylamino)-1-oxo-3-phenylpropan-2-yl)pyrrolidine-2-carboxamide::CHEMBL1084186 Mu-type opioid receptor Cavia cutleri 25 ChEMBL 10.1021/jm1001343 10.7270/Q23F4PTK 20476738 Torino, D; Mollica, A; Pinnen, F; Feliciani, F; Lucente, G; Fabrizi, G; Portalone, G; Davis, P; Lai, J; Ma, SW; Porreca, F; Hruby, VJ Universit£ di Roma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50320022 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50320022&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46831098 104141551 CHEMBL1084186 ZINC53227603 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50580925 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N\C(=C/c1ccccc1)C(=O)N\C(=C/c1ccccc1)C(N)=O InChI=1S/C32H33N5O5/c33-25(18-23-13-15-24(38)16-14-23)32(42)37-17-7-12-28(37)31(41)36-27(20-22-10-5-2-6-11-22)30(40)35-26(29(34)39)19-21-8-3-1-4-9-21/h1-6,8-11,13-16,19-20,25,28,38H,7,12,17-18,33H2,(H2,34,39)(H,35,40)(H,36,41)/b26-19-,27-20-/t25-,28-/m0/s1 XFYFZIUMRTWCIL-INUMRJPYSA-N 50320023 (S)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)-N-(3-((Z)-3-amino-3-oxo-1-phenylprop-1-en-2-ylamino)-3-oxo-1-phenylprop-1-en-2-yl)pyrrolidine-2-carboxamide::CHEMBL1084187 Mu-type opioid receptor Cavia cutleri 330 ChEMBL 10.1021/jm1001343 10.7270/Q23F4PTK 20476738 Torino, D; Mollica, A; Pinnen, F; Feliciani, F; Lucente, G; Fabrizi, G; Portalone, G; Davis, P; Lai, J; Ma, SW; Porreca, F; Hruby, VJ Universit£ di Roma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50320023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50320023&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46831100 104141552 CHEMBL1084187 ZINC53227601 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50581009 CN[C@@H]1Cc2ccc(O)c3O[C@@H]4[C@@H]([C@H]1CCC4=O)c23 InChI=1S/C15H17NO3/c1-16-9-6-7-2-4-10(17)14-12(7)13-8(9)3-5-11(18)15(13)19-14/h2,4,8-9,13,15-17H,3,5-6H2,1H3/t8-,9+,13-,15-/m0/s1 UDUUTPVGZGPZHK-YPSFTXJRSA-N 50320083 (2R,2aR,2a1S,5aR)-7-hydroxy-2-(methylamino)-2,2a,2a1,3,4,5a-hexahydrophenanthro[4,5-bcd]furan-5(1H)-one::CHEMBL1082709 Mu-type opioid receptor Cavia cutleri 164 ChEMBL 10.1016/j.bmcl.2010.04.080 10.7270/Q2KD1Z3B 20483601 Nagase, H; Imaide, S; Tomatsu, M; Nemoto, T; Nakajima, M; Nakao, K; Mochizuki, H; Fujii, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50320083 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50320083&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46891325 104141612 CHEMBL1082709 ZINC49036082 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50581010 Oc1ccc2C[C@@H](NCC3CC3)[C@@H]3CCC(=O)[C@@H]4Oc1c2[C@H]34 InChI=1S/C18H21NO3/c20-13-5-3-10-7-12(19-8-9-1-2-9)11-4-6-14(21)18-16(11)15(10)17(13)22-18/h3,5,9,11-12,16,18-20H,1-2,4,6-8H2/t11-,12+,16-,18-/m0/s1 NZQNKNYYLWWVAO-GWLLULGVSA-N 50320084 (2R,2aR,2a1S,5aR)-2-(cyclopropylmethylamino)-7-hydroxy-2,2a,2a1,3,4,5a-hexahydrophenanthro[4,5-bcd]furan-5(1H)-one::CHEMBL1083953 Mu-type opioid receptor Cavia cutleri 30.3 ChEMBL 10.1016/j.bmcl.2010.04.080 10.7270/Q2KD1Z3B 20483601 Nagase, H; Imaide, S; Tomatsu, M; Nemoto, T; Nakajima, M; Nakao, K; Mochizuki, H; Fujii, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50320084 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50320084&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46891326 104141613 CHEMBL1083953 ZINC49035291 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50581011 CN(C)[C@@H]1Cc2ccc(O)c3O[C@@H]4[C@@H]([C@H]1CCC4=O)c23 InChI=1S/C16H19NO3/c1-17(2)10-7-8-3-5-11(18)15-13(8)14-9(10)4-6-12(19)16(14)20-15/h3,5,9-10,14,16,18H,4,6-7H2,1-2H3/t9-,10+,14-,16-/m0/s1 CSVLEYSXJQMIOF-UEVPNFDOSA-N 50320085 (2R,2aR,2a1S,5aR)-2-(dimethylamino)-7-hydroxy-2,2a,2a1,3,4,5a-hexahydrophenanthro[4,5-bcd]furan-5(1H)-one::CHEMBL1082400 Mu-type opioid receptor Cavia cutleri 50.9 ChEMBL 10.1016/j.bmcl.2010.04.080 10.7270/Q2KD1Z3B 20483601 Nagase, H; Imaide, S; Tomatsu, M; Nemoto, T; Nakajima, M; Nakao, K; Mochizuki, H; Fujii, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50320085 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50320085&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46891366 104141614 CHEMBL1082400 ZINC49037310 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50581012 CN(CC1CC1)[C@@H]1Cc2ccc(O)c3O[C@@H]4[C@@H]([C@H]1CCC4=O)c23 InChI=1S/C19H23NO3/c1-20(9-10-2-3-10)13-8-11-4-6-14(21)18-16(11)17-12(13)5-7-15(22)19(17)23-18/h4,6,10,12-13,17,19,21H,2-3,5,7-9H2,1H3/t12-,13+,17-,19-/m0/s1 VRIULMSJRSWRDW-JBYDNAENSA-N 50320086 (2R,2aR,2a1S,5aR)-2-((cyclopropylmethyl)(methyl)amino)-7-hydroxy-2,2a,2a1,3,4,5a-hexahydrophenanthro[4,5-bcd]furan-5(1H)-one::CHEMBL1082323 Mu-type opioid receptor Cavia cutleri 3.36 ChEMBL 10.1016/j.bmcl.2010.04.080 10.7270/Q2KD1Z3B 20483601 Nagase, H; Imaide, S; Tomatsu, M; Nemoto, T; Nakajima, M; Nakao, K; Mochizuki, H; Fujii, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50320086 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50320086&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46891367 104141615 CHEMBL1082323 ZINC49036059 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50581013 CN[C@@H]1Cc2ccc(O)c3O[C@@H]4[C@H](c23)[C@@]1(O)CCC4=O InChI=1S/C15H17NO4/c1-16-10-6-7-2-3-8(17)13-11(7)12-14(20-13)9(18)4-5-15(10,12)19/h2-3,10,12,14,16-17,19H,4-6H2,1H3/t10-,12+,14+,15-/m1/s1 QZHUAWRQHJKQMI-UEEZHKSASA-N 50320087 (2R,2aS,2a1S,5aR)-2a,7-dihydroxy-2-(methylamino)-2,2a,2a1,3,4,5a-hexahydrophenanthro[4,5-bcd]furan-5(1H)-one::CHEMBL1082638 Mu-type opioid receptor Cavia cutleri 118 ChEMBL 10.1016/j.bmcl.2010.04.080 10.7270/Q2KD1Z3B 20483601 Nagase, H; Imaide, S; Tomatsu, M; Nemoto, T; Nakajima, M; Nakao, K; Mochizuki, H; Fujii, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50320087 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50320087&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46891368 104141616 CHEMBL1082638 ZINC49089707 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50581014 Oc1ccc2C[C@@H](NCC3CC3)[C@]3(O)CCC(=O)[C@@H]4Oc1c2[C@H]34 InChI=1S/C18H21NO4/c20-11-4-3-10-7-13(19-8-9-1-2-9)18(22)6-5-12(21)17-15(18)14(10)16(11)23-17/h3-4,9,13,15,17,19-20,22H,1-2,5-8H2/t13-,15+,17+,18-/m1/s1 GXNVNSDJAHJVRA-HUHSQHJXSA-N 50320088 (2R,2aS,2a1S,5aR)-2-(cyclopropylmethylamino)-2a,7-dihydroxy-2,2a,2a1,3,4,5a-hexahydrophenanthro[4,5-bcd]furan-5(1H)-one::CHEMBL1082639 Mu-type opioid receptor Cavia cutleri 24.7 ChEMBL 10.1016/j.bmcl.2010.04.080 10.7270/Q2KD1Z3B 20483601 Nagase, H; Imaide, S; Tomatsu, M; Nemoto, T; Nakajima, M; Nakao, K; Mochizuki, H; Fujii, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50320088 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50320088&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46891369 104141617 CHEMBL1082639 ZINC49036074 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50581015 CN(C)[C@@H]1Cc2ccc(O)c3O[C@@H]4[C@H](c23)[C@@]1(O)CCC4=O InChI=1S/C16H19NO4/c1-17(2)11-7-8-3-4-9(18)14-12(8)13-15(21-14)10(19)5-6-16(11,13)20/h3-4,11,13,15,18,20H,5-7H2,1-2H3/t11-,13+,15+,16-/m1/s1 CGWHWXOGSRSKEI-SHPPOPEUSA-N 50320089 (2R,2aS,2a1S,5aR)-2-(dimethylamino)-2a,7-dihydroxy-2,2a,2a1,3,4,5a-hexahydrophenanthro[4,5-bcd]furan-5(1H)-one::CHEMBL1082640 Mu-type opioid receptor Cavia cutleri 8.95 ChEMBL 10.1016/j.bmcl.2010.04.080 10.7270/Q2KD1Z3B 20483601 Nagase, H; Imaide, S; Tomatsu, M; Nemoto, T; Nakajima, M; Nakao, K; Mochizuki, H; Fujii, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50320089 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50320089&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46891370 104141618 CHEMBL1082640 ZINC49089708 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50581016 CN(CC1CC1)[C@@H]1Cc2ccc(O)c3O[C@@H]4[C@H](c23)[C@@]1(O)CCC4=O InChI=1S/C19H23NO4/c1-20(9-10-2-3-10)14-8-11-4-5-12(21)17-15(11)16-18(24-17)13(22)6-7-19(14,16)23/h4-5,10,14,16,18,21,23H,2-3,6-9H2,1H3/t14-,16+,18+,19-/m1/s1 XPRKYCPOASGVCM-TWKWOARYSA-N 50320090 (2R,2aS,2a1S,5aR)-2-((cyclopropylmethyl)(methyl)amino)-2a,7-dihydroxy-2,2a,2a1,3,4,5a-hexahydrophenanthro[4,5-bcd]furan-5(1H)-one::CHEMBL1082968 Mu-type opioid receptor Cavia cutleri 1.17 ChEMBL 10.1016/j.bmcl.2010.04.080 10.7270/Q2KD1Z3B 20483601 Nagase, H; Imaide, S; Tomatsu, M; Nemoto, T; Nakajima, M; Nakao, K; Mochizuki, H; Fujii, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50320090 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50320090&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46891419 104141619 CHEMBL1082968 ZINC49089448 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50581017 Oc1ccc2C[C@H]3N(CC4CC4)CCO[C@]33CCC(=O)[C@@H]4Oc1c2[C@H]34 InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24-8-7-21(15)10-11-1-2-11)6-5-14(23)19-17(20)16(12)18(13)25-19/h3-4,11,15,17,19,22H,1-2,5-10H2/t15-,17+,19+,20-/m1/s1 CWIDPMIXWFCKMC-DJABAAGCSA-N 50320091 (1R,5S,10R,18S)-9-(cyclopropylmethyl)-15-hydroxy-6,19-dioxa-9-azapentacyclo[14.2.1.0^{5,10}.0^{5,18}.0^{12,17}]nonadeca-12(17),13,15-trien-2-one::CHEMBL1082969 Mu-type opioid receptor Cavia cutleri 294 ChEMBL 10.1016/j.bmcl.2010.04.080 10.7270/Q2KD1Z3B 20483601 Nagase, H; Imaide, S; Tomatsu, M; Nemoto, T; Nakajima, M; Nakao, K; Mochizuki, H; Fujii, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50320091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50320091&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46891420 104141620 CHEMBL1082969 ZINC49036720 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50581018 CN1CCO[C@@]23CCC(=O)[C@@H]4Oc5c([C@H]24)c(C[C@@H]13)ccc5O InChI=1S/C17H19NO4/c1-18-6-7-21-17-5-4-11(20)16-14(17)13-9(8-12(17)18)2-3-10(19)15(13)22-16/h2-3,12,14,16,19H,4-8H2,1H3/t12-,14+,16+,17-/m1/s1 OJFSPPAOLNIANA-NQZOLGFYSA-N 50320092 (1R,5S,10R,18S)-15-hydroxy-9-methyl-6,19-dioxa-9-azapentacyclo[14.2.1.0^{5,10}.0^{5,18}.0^{12,17}]nonadeca-12(17),13,15-trien-2-one::CHEMBL1082970 Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1016/j.bmcl.2010.04.080 10.7270/Q2KD1Z3B 20483601 Nagase, H; Imaide, S; Tomatsu, M; Nemoto, T; Nakajima, M; Nakao, K; Mochizuki, H; Fujii, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50320092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50320092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46891421 104141621 CHEMBL1082970 ZINC49036722 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50581030 Oc1ccc2C[C@H]3N4CCO[C@]33CCC(=O)[C@@H]5Oc1c2[C@]35CC4 InChI=1S/C18H19NO4/c20-11-2-1-10-9-13-18-4-3-12(21)16-17(18,14(10)15(11)23-16)5-6-19(13)7-8-22-18/h1-2,13,16,20H,3-9H2/t13-,16+,17+,18-/m1/s1 WHHABWIVYGQQPU-XFKAJCMBSA-N 50320093 (1S,5R,13S,20R)-8-hydroxy-6,19-dioxa-16-azahexacyclo[9.8.2.0^{1,13}.0^{5,13}.0^{7,12}.0^{16,20}]henicosa-7,9,11-trien-4-one::CHEMBL1082971 Mu-type opioid receptor Cavia cutleri 86 ChEMBL 10.1016/j.bmcl.2010.04.080 10.7270/Q2KD1Z3B 20483601 Nagase, H; Imaide, S; Tomatsu, M; Nemoto, T; Nakajima, M; Nakao, K; Mochizuki, H; Fujii, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50320093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50320093&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46891422 104141622 CHEMBL1082971 ZINC49090051 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50589548 CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C59H70F6N10O9S/c1-33(2)23-46(54(81)73-48(28-38-31-67-44-14-9-8-13-42(38)44)53(80)68-30-37-24-39(58(60,61)62)29-40(25-37)59(63,64)65)74-56(83)49-15-10-21-75(49)57(84)45(20-22-85-4)72-55(82)47(27-35-11-6-5-7-12-35)71-50(77)32-69-51(78)34(3)70-52(79)43(66)26-36-16-18-41(76)19-17-36/h5-9,11-14,16-19,24-25,29,31,33-34,43,45-49,67,76H,10,15,20-23,26-28,30,32,66H2,1-4H3,(H,68,80)(H,69,78)(H,70,79)(H,71,77)(H,72,82)(H,73,81)(H,74,83)/t34-,43+,45+,46+,47+,48+,49+/m1/s1 UTXLSPLKQGPIPL-WXYSSXJFSA-N 50264406 (S)-1-((2S,5S,11R,14S)-14-amino-5-benzyl-15-(4-hydroxyphenyl)-11-methyl-2-(2-(methylthio)ethyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane)-N-((S)-1-((S)-1-(3,5-bis(trifluoromethyl)benzylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-4-methyl-1-oxopentan-2-yl)pyrrolidine-2-carboxamide::CHEMBL507340::H-Tyr-D-Ala-Gly-Phe-Met-Pro-Leu-Trp-NH-[3',5'-(CF3)2Bzl]::Tyr-D-Ala-Gly-Phe-Met-Pro-Leu-Trp-NH-3,5-Bzl(CF 3) 2 Mu-type opioid receptor Cavia cutleri 420 ChEMBL 10.1021/jm100157m 10.7270/Q21N81BD 20617791 Yamamoto, T; Nair, P; Jacobsen, NE; Kulkarni, V; Davis, P; Ma, SW; Navratilova, E; Yamamura, HI; Vanderah, TW; Porreca, F; Lai, J; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264406 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264406&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25129133 104112429 CHEMBL507340 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50589550 CC1(C)SSC(C)(C)[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H]1C(O)=O InChI=1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21-,23+,24-/m0/s1 MCMMCRYPQBNCPH-ZQRMPTRQSA-N 50323870 (4S,7S,13R)-13-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid::CHEMBL1214076 Mu-type opioid receptor Cavia cutleri 6930 ChEMBL 10.1021/jm100157m 10.7270/Q21N81BD 20617791 Yamamoto, T; Nair, P; Jacobsen, NE; Kulkarni, V; Davis, P; Ma, SW; Navratilova, E; Yamamura, HI; Vanderah, TW; Porreca, F; Lai, J; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323870&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 49863750 117645191 CHEMBL1214076 ZINC29314254 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50599618 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C32H37N5O5/c33-25(18-23-13-15-24(38)16-14-23)32(42)37-17-7-12-28(37)31(41)36-27(20-22-10-5-2-6-11-22)30(40)35-26(29(34)39)19-21-8-3-1-4-9-21/h1-6,8-11,13-16,25-28,38H,7,12,17-20,33H2,(H2,34,39)(H,35,40)(H,36,41)/t25-,26-,27-,28-/m0/s1 XIJHWXXXIMEHKW-LJWNLINESA-N 50139013 (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::(S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxamide::1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylicacid[1-((S)-(S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL333357::H-Tyr-Pro-Phe-Phe-NH2::Tyr-Pro-Phe-Phe-NH2::endomorphin-2 Mu-type opioid receptor Cavia cutleri 15 ChEMBL 10.1016/j.ejmech.2010.07.022 10.7270/Q2KK9C0Q 20692738 Giordano, C; Sansone, A; Masi, A; Lucente, G; Punzi, P; Mollica, A; Pinnen, F; Feliciani, F; Cacciatore, I; Davis, P; Lai, J; Ma, SW; Porreca, F; Hruby, V Sapienza University of Rome http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139013&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311081 104029000 CHEMBL333357 3668 ZINC14951634 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50599619 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1CC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C33H39N5O5/c34-27(18-24-13-15-26(39)16-14-24)33(43)38-17-7-12-25(38)21-30(40)36-29(20-23-10-5-2-6-11-23)32(42)37-28(31(35)41)19-22-8-3-1-4-9-22/h1-6,8-11,13-16,25,27-29,39H,7,12,17-21,34H2,(H2,35,41)(H,36,40)(H,37,42)/t25-,27-,28-,29-/m0/s1 HEVKQILECXRYNK-AMEOFWRWSA-N 50326885 (S)-N-((S)-1-amino-1-oxo-3-phenylpropan-2-yl)-2-(2-((S)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidin-2-yl)acetamido)-3-phenylpropanamide::CHEMBL1253632 Mu-type opioid receptor Cavia cutleri 260 ChEMBL 10.1016/j.ejmech.2010.07.022 10.7270/Q2KK9C0Q 20692738 Giordano, C; Sansone, A; Masi, A; Lucente, G; Punzi, P; Mollica, A; Pinnen, F; Feliciani, F; Cacciatore, I; Davis, P; Lai, J; Ma, SW; Porreca, F; Hruby, V Sapienza University of Rome http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326885&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46947654 123106000 CHEMBL1253632 ZINC64470219 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50599620 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@@H]1CC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C33H39N5O5/c34-27(18-24-13-15-26(39)16-14-24)33(43)38-17-7-12-25(38)21-30(40)36-29(20-23-10-5-2-6-11-23)32(42)37-28(31(35)41)19-22-8-3-1-4-9-22/h1-6,8-11,13-16,25,27-29,39H,7,12,17-21,34H2,(H2,35,41)(H,36,40)(H,37,42)/t25-,27+,28+,29+/m1/s1 HEVKQILECXRYNK-ZIZDPRJYSA-N 50326884 (S)-N-((S)-1-amino-1-oxo-3-phenylpropan-2-yl)-2-(2-((R)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidin-2-yl)acetamido)-3-phenylpropanamide::CHEMBL1253633 Mu-type opioid receptor Cavia cutleri 420 ChEMBL 10.1016/j.ejmech.2010.07.022 10.7270/Q2KK9C0Q 20692738 Giordano, C; Sansone, A; Masi, A; Lucente, G; Punzi, P; Mollica, A; Pinnen, F; Feliciani, F; Cacciatore, I; Davis, P; Lai, J; Ma, SW; Porreca, F; Hruby, V Sapienza University of Rome http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326884&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46947656 123105999 CHEMBL1253633 ZINC64403862 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50599621 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1CS(=O)(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C32H39N5O6S/c33-27(18-24-13-15-26(38)16-14-24)32(41)37-17-7-12-25(37)21-44(42,43)36-29(20-23-10-5-2-6-11-23)31(40)35-28(30(34)39)19-22-8-3-1-4-9-22/h1-6,8-11,13-16,25,27-29,36,38H,7,12,17-21,33H2,(H2,34,39)(H,35,40)/t25-,27-,28-,29-/m0/s1 FSPHKCSMYIGZLU-AMEOFWRWSA-N 50326883 (S)-N-((S)-1-amino-1-oxo-3-phenylpropan-2-yl)-2-(((S)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidin-2-yl)methylsulfonamido)-3-phenylpropanamide::CHEMBL1253634 Mu-type opioid receptor Cavia cutleri 730 ChEMBL 10.1016/j.ejmech.2010.07.022 10.7270/Q2KK9C0Q 20692738 Giordano, C; Sansone, A; Masi, A; Lucente, G; Punzi, P; Mollica, A; Pinnen, F; Feliciani, F; Cacciatore, I; Davis, P; Lai, J; Ma, SW; Porreca, F; Hruby, V Sapienza University of Rome http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326883 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326883&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46944687 123105998 CHEMBL1253634 ZINC64409744 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50599622 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@@H]1CS(=O)(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C32H39N5O6S/c33-27(18-24-13-15-26(38)16-14-24)32(41)37-17-7-12-25(37)21-44(42,43)36-29(20-23-10-5-2-6-11-23)31(40)35-28(30(34)39)19-22-8-3-1-4-9-22/h1-6,8-11,13-16,25,27-29,36,38H,7,12,17-21,33H2,(H2,34,39)(H,35,40)/t25-,27+,28+,29+/m1/s1 FSPHKCSMYIGZLU-ZIZDPRJYSA-N 50326890 (S)-N-((S)-1-amino-1-oxo-3-phenylpropan-2-yl)-2-(((R)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidin-2-yl)methylsulfonamido)-3-phenylpropanamide::CHEMBL1253635 Mu-type opioid receptor Cavia cutleri 2700 ChEMBL 10.1016/j.ejmech.2010.07.022 10.7270/Q2KK9C0Q 20692738 Giordano, C; Sansone, A; Masi, A; Lucente, G; Punzi, P; Mollica, A; Pinnen, F; Feliciani, F; Cacciatore, I; Davis, P; Lai, J; Ma, SW; Porreca, F; Hruby, V Sapienza University of Rome http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326890&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46944689 123106005 CHEMBL1253635 ZINC64403854 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50599623 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CC[C@@H](C1)S(=O)(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C31H37N5O6S/c32-26(17-23-11-13-24(37)14-12-23)31(40)36-16-15-25(20-36)43(41,42)35-28(19-22-9-5-2-6-10-22)30(39)34-27(29(33)38)18-21-7-3-1-4-8-21/h1-14,25-28,35,37H,15-20,32H2,(H2,33,38)(H,34,39)/t25-,26-,27-,28-/m0/s1 UNASWFPNYIABKP-LJWNLINESA-N 50326889 (S)-N-((S)-1-amino-1-oxo-3-phenylpropan-2-yl)-2-((S)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-3-sulfonamido)-3-phenylpropanamide::CHEMBL1253636 Mu-type opioid receptor Cavia cutleri 260 ChEMBL 10.1016/j.ejmech.2010.07.022 10.7270/Q2KK9C0Q 20692738 Giordano, C; Sansone, A; Masi, A; Lucente, G; Punzi, P; Mollica, A; Pinnen, F; Feliciani, F; Cacciatore, I; Davis, P; Lai, J; Ma, SW; Porreca, F; Hruby, V Sapienza University of Rome http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326889 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326889&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46944691 123106004 CHEMBL1253636 ZINC64403835 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50599624 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CC[C@H](C1)S(=O)(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C31H37N5O6S/c32-26(17-23-11-13-24(37)14-12-23)31(40)36-16-15-25(20-36)43(41,42)35-28(19-22-9-5-2-6-10-22)30(39)34-27(29(33)38)18-21-7-3-1-4-8-21/h1-14,25-28,35,37H,15-20,32H2,(H2,33,38)(H,34,39)/t25-,26+,27+,28+/m1/s1 UNASWFPNYIABKP-UNFRKHOWSA-N 50326888 (S)-N-((S)-1-amino-1-oxo-3-phenylpropan-2-yl)-2-((R)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-3-sulfonamido)-3-phenylpropanamide::CHEMBL1253637 Mu-type opioid receptor Cavia cutleri 220 ChEMBL 10.1016/j.ejmech.2010.07.022 10.7270/Q2KK9C0Q 20692738 Giordano, C; Sansone, A; Masi, A; Lucente, G; Punzi, P; Mollica, A; Pinnen, F; Feliciani, F; Cacciatore, I; Davis, P; Lai, J; Ma, SW; Porreca, F; Hruby, V Sapienza University of Rome http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326888&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46944693 123106003 CHEMBL1253637 ZINC64409746 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50599625 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1CC(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@@H]1C(N)=O InChI=1S/C29H37N5O5/c30-23(16-20-10-12-22(35)13-11-20)28(38)33-14-4-8-21(33)18-26(36)32-24(17-19-6-2-1-3-7-19)29(39)34-15-5-9-25(34)27(31)37/h1-3,6-7,10-13,21,23-25,35H,4-5,8-9,14-18,30H2,(H2,31,37)(H,32,36)/t21-,23-,24-,25+/m0/s1 CRCDRPXNSXPMAX-BELIEFIBSA-N 50326887 (R)-1-((S)-2-(2-((S)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidin-2-yl)acetamido)-3-phenylpropanoyl)pyrrolidine-2-carboxamide::CHEMBL1254974 Mu-type opioid receptor Cavia cutleri 1100 ChEMBL 10.1016/j.ejmech.2010.07.022 10.7270/Q2KK9C0Q 20692738 Giordano, C; Sansone, A; Masi, A; Lucente, G; Punzi, P; Mollica, A; Pinnen, F; Feliciani, F; Cacciatore, I; Davis, P; Lai, J; Ma, SW; Porreca, F; Hruby, V Sapienza University of Rome http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326887 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326887&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 52948292 123106002 CHEMBL1254974 ZINC64417148 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50599626 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@@H]1CC(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@@H]1C(N)=O InChI=1S/C29H37N5O5/c30-23(16-20-10-12-22(35)13-11-20)28(38)33-14-4-8-21(33)18-26(36)32-24(17-19-6-2-1-3-7-19)29(39)34-15-5-9-25(34)27(31)37/h1-3,6-7,10-13,21,23-25,35H,4-5,8-9,14-18,30H2,(H2,31,37)(H,32,36)/t21-,23+,24+,25-/m1/s1 CRCDRPXNSXPMAX-DDKRZIBASA-N 50326886 (R)-1-((S)-2-(2-((R)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidin-2-yl)acetamido)-3-phenylpropanoyl)pyrrolidine-2-carboxamide::CHEMBL1255058 Mu-type opioid receptor Cavia cutleri 17 ChEMBL 10.1016/j.ejmech.2010.07.022 10.7270/Q2KK9C0Q 20692738 Giordano, C; Sansone, A; Masi, A; Lucente, G; Punzi, P; Mollica, A; Pinnen, F; Feliciani, F; Cacciatore, I; Davis, P; Lai, J; Ma, SW; Porreca, F; Hruby, V Sapienza University of Rome http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326886 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326886&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 52941055 123106001 CHEMBL1255058 ZINC64454144 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50590029 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](CC(O)=O)c1nc2ccccc2[nH]1 InChI=1S/C31H33N5O5/c1-17-11-21(37)12-18(2)22(17)14-23(32)31(41)36-16-20-8-4-3-7-19(20)13-27(36)30(40)35-26(15-28(38)39)29-33-24-9-5-6-10-25(24)34-29/h3-12,23,26-27,37H,13-16,32H2,1-2H3,(H,33,34)(H,35,40)(H,38,39)/t23-,26-,27-/m0/s1 USVQTDLSVBRMCR-YGPDHOBYSA-N 50272169 (S)-3-((S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido)-3-(1H-benzo[d]imidazol-2-yl)propanoic acid::3-({2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-3-(1H-benzoimidazol-2-yl)-propionic acid::CHEMBL442577::H-Dmt-Tic-NH-(S)CH(CH2-COOH)-Bid::UFP-512 Mu-type opioid receptor Cavia cutleri 1724 ChEMBL 10.1016/j.bmc.2010.06.073 10.7270/Q2MG7PPX 20637637 Balboni, G; Marzola, E; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50272169 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50272169&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10918703 104116657 CHEMBL442577 ZINC27631810 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50590030 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCc1nc2ccccc2[nH]1 InChI=1S/C29H31N5O3/c1-17-11-21(35)12-18(2)22(17)14-23(30)29(37)34-16-20-8-4-3-7-19(20)13-26(34)28(36)31-15-27-32-24-9-5-6-10-25(24)33-27/h3-12,23,26,35H,13-16,30H2,1-2H3,(H,31,36)(H,32,33)/t23-,26-/m0/s1 XRZTZWCPHAJWJQ-OZXSUGGESA-N 50179191 (S)-N-((1H-benzo[d]imidazol-2-yl)methyl)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid (1H-benzoimidazol-2-ylmethyl)-amide::CHEMBL109390::H-Dmt-Tic-NH-CH2-Bid::UFP-502 Mu-type opioid receptor Cavia cutleri 26.92 ChEMBL 10.1016/j.bmc.2010.06.073 10.7270/Q2MG7PPX 20637637 Balboni, G; Marzola, E; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179191&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10345770 104064419 CHEMBL109390 ZINC13472298 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50590031 N[C@@H](Cc1c(F)cc(O)cc1F)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCc1nc2ccccc2[nH]1 InChI=1S/C27H25F2N5O3/c28-19-10-17(35)11-20(29)18(19)12-21(30)27(37)34-14-16-6-2-1-5-15(16)9-24(34)26(36)31-13-25-32-22-7-3-4-8-23(22)33-25/h1-8,10-11,21,24,35H,9,12-14,30H2,(H,31,36)(H,32,33)/t21-,24-/m0/s1 ZTUUPZLTZQOFHG-URXFXBBRSA-N 50324021 (S)-N-((1H-benzo[d]imidazol-2-yl)methyl)-2-((S)-2-amino-3-(2,6-difluoro-4-hydroxyphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::CHEMBL1213987 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1016/j.bmc.2010.06.073 10.7270/Q2MG7PPX 20637637 Balboni, G; Marzola, E; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50324021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50324021&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 49863720 117645342 CHEMBL1213987 ZINC58541213 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50590032 N[C@@H](Cc1ccc(O)cc1)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCc1nc2ccccc2[nH]1 InChI=1S/C27H27N5O3/c28-21(13-17-9-11-20(33)12-10-17)27(35)32-16-19-6-2-1-5-18(19)14-24(32)26(34)29-15-25-30-22-7-3-4-8-23(22)31-25/h1-12,21,24,33H,13-16,28H2,(H,29,34)(H,30,31)/t21-,24-/m0/s1 JKXJJLHYGBYWBT-URXFXBBRSA-N 50324022 (S)-N-((1H-benzo[d]imidazol-2-yl)methyl)-2-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::CHEMBL1213988 Mu-type opioid receptor Cavia cutleri 4216 ChEMBL 10.1016/j.bmc.2010.06.073 10.7270/Q2MG7PPX 20637637 Balboni, G; Marzola, E; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50324022 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50324022&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 49863721 117645343 CHEMBL1213988 ZINC58541284 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50590033 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(C)C)C(=O)NCC(N)=O InChI=1S/C49H67N9O12/c1-25(2)41(48(69)52-24-39(51)61)58-49(70)42(26(3)4)57-45(66)36(17-18-40(62)63)54-47(68)38(21-30-11-9-8-10-12-30)55-43(64)29(7)53-46(67)37(22-31-13-15-32(59)16-14-31)56-44(65)35(50)23-34-27(5)19-33(60)20-28(34)6/h8-16,19-20,25-26,29,35-38,41-42,59-60H,17-18,21-24,50H2,1-7H3,(H2,51,61)(H,52,69)(H,53,67)(H,54,68)(H,55,64)(H,56,65)(H,57,66)(H,58,70)(H,62,63)/t29-,35+,36+,37+,38+,41+,42+/m1/s1 UYLUQCREUVDEDF-RWVHMXOYSA-N 50324023 (2S,5S,8R,11S,14S)-2-amino-14-((S)-1-((S)-1-(2-amino-2-oxoethylamino)-3-methyl-1-oxobutan-2-ylamino)-3-methyl-1-oxobutan-2-ylcarbamoyl)-11-benzyl-1-(4-hydroxy-2,6-dimethylphenyl)-5-(4-hydroxybenzyl)-8-methyl-3,6,9,12-tetraoxo-4,7,10,13-tetraazaheptadecan-17-oic acid::CHEMBL1213989 Mu-type opioid receptor Cavia cutleri 48.2 ChEMBL 10.1016/j.bmc.2010.06.073 10.7270/Q2MG7PPX 20637637 Balboni, G; Marzola, E; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50324023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50324023&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 49863722 117645344 CHEMBL1213989 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50590034 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)Cc1c(F)cc(O)cc1F)C(C)C)C(=O)NCC(N)=O InChI=1S/C47H61F2N9O12/c1-23(2)39(46(69)52-22-37(51)61)58-47(70)40(24(3)4)57-43(66)34(15-16-38(62)63)54-45(68)36(17-26-9-7-6-8-10-26)55-41(64)25(5)53-44(67)35(18-27-11-13-28(59)14-12-27)56-42(65)33(50)21-30-31(48)19-29(60)20-32(30)49/h6-14,19-20,23-25,33-36,39-40,59-60H,15-18,21-22,50H2,1-5H3,(H2,51,61)(H,52,69)(H,53,67)(H,54,68)(H,55,64)(H,56,65)(H,57,66)(H,58,70)(H,62,63)/t25-,33+,34+,35+,36+,39+,40+/m1/s1 BBXVKTVPOYINAV-PJJOLMOESA-N 50324024 (2S,5S,8R,11S,14S)-2-amino-14-((S)-1-((S)-1-(2-amino-2-oxoethylamino)-3-methyl-1-oxobutan-2-ylamino)-3-methyl-1-oxobutan-2-ylcarbamoyl)-11-benzyl-1-(2,6-difluoro-4-hydroxyphenyl)-5-(4-hydroxybenzyl)-8-methyl-3,6,9,12-tetraoxo-4,7,10,13-tetraazaheptadecan-17-oic acid::CHEMBL1213990 Mu-type opioid receptor Cavia cutleri 3559 ChEMBL 10.1016/j.bmc.2010.06.073 10.7270/Q2MG7PPX 20637637 Balboni, G; Marzola, E; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50324024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50324024&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 49863723 117645345 CHEMBL1213990 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50593407 CN([C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45)C(=O)\C=C\c1ccoc1 InChI=1S/C28H32N2O5/c1-29(23(32)7-4-18-9-13-34-16-18)20-8-10-28(33)22-14-19-5-6-21(31)25-24(19)27(28,26(20)35-25)11-12-30(22)15-17-2-3-17/h4-7,9,13,16-17,20,22,26,31,33H,2-3,8,10-12,14-15H2,1H3/b7-4+/t20-,22-,26+,27+,28-/m1/s1 XGZZHZMWIXFATA-UEZBDDGYSA-N 50325534 CHEMBL267495::nalfurafine Mu-type opioid receptor Cavia cutleri 0.582 ChEMBL 10.1016/j.bmcl.2010.07.035 10.7270/Q2CJ8DPH 20685120 Fujii, H; Ida, Y; Hanamura, S; Osa, Y; Nemoto, T; Nakajima, M; Hasebe, K; Nakao, K; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325534&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search IVB 7YIT 6445230 117646855 CHEMBL267495 1651 ZINC04393014 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50593408 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2[C@@H]4Oc6c7c(C[C@H]8N(CC9CC9)CC[C@@]47[C@@]8(O)Cc2c1C[C@@]35O)ccc6O InChI=1S/C40H43N3O6/c44-25-7-5-21-13-27-39(46)15-23-24-16-40(47)28-14-22-6-8-26(45)34-30(22)38(40,10-12-43(28)18-20-3-4-20)36(49-34)32(24)41-31(23)35-37(39,29(21)33(25)48-35)9-11-42(27)17-19-1-2-19/h5-8,19-20,27-28,35-36,41,44-47H,1-4,9-18H2/t27-,28-,35+,36+,37+,38+,39-,40-/m1/s1 APSUXPSYBJVPPS-YAUKWVCOSA-N 82551 C18130::CAS_105618-26-6::NOR-BNI (HCI)2::NORBNI Mu-type opioid receptor Cavia cutleri 28.2 ChEMBL 10.1016/j.bmcl.2010.07.035 10.7270/Q2CJ8DPH 20685120 Fujii, H; Ida, Y; Hanamura, S; Osa, Y; Nemoto, T; Nakajima, M; Hasebe, K; Nakao, K; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82551&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5480230 136350521 C18130 ZINC03995590 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50593409 Cn1c(C=CC(=O)CCc2ccccc2)cc2C[C@@]3(O)[C@H]4Cc5ccc(O)c6O[C@@H](c12)[C@]3(CCN4CC1CC1)c56 InChI=1S/C34H36N2O4/c1-35-25(11-13-26(37)12-9-21-5-3-2-4-6-21)17-24-19-34(39)28-18-23-10-14-27(38)31-29(23)33(34,32(40-31)30(24)35)15-16-36(28)20-22-7-8-22/h2-6,10-11,13-14,17,22,28,32,38-39H,7-9,12,15-16,18-20H2,1H3/t28-,32+,33+,34-/m1/s1 KZYWRUBRYYIVAN-XZLGBSMGSA-N 50325526 CHEMBL1223773 Mu-type opioid receptor Cavia cutleri 6.89 ChEMBL 10.1016/j.bmcl.2010.07.035 10.7270/Q2CJ8DPH 20685120 Fujii, H; Ida, Y; Hanamura, S; Osa, Y; Nemoto, T; Nakajima, M; Hasebe, K; Nakao, K; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325526 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325526&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 42608559 117646847 CHEMBL1223773 ZINC58591811 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50593410 Cn1c(C=CC(=O)Cc2ccccc2)cc2C[C@@]3(O)[C@H]4Cc5ccc(O)c6O[C@@H](c12)[C@]3(CCN4CC1CC1)c56 InChI=1S/C33H34N2O4/c1-34-24(10-11-25(36)15-20-5-3-2-4-6-20)16-23-18-33(38)27-17-22-9-12-26(37)30-28(22)32(33,31(39-30)29(23)34)13-14-35(27)19-21-7-8-21/h2-6,9-12,16,21,27,31,37-38H,7-8,13-15,17-19H2,1H3/t27-,31+,32+,33-/m1/s1 PNVAUVMLVVGKGB-OUDZLNJNSA-N 50325527 CHEMBL1223774 Mu-type opioid receptor Cavia cutleri 6.58 ChEMBL 10.1016/j.bmcl.2010.07.035 10.7270/Q2CJ8DPH 20685120 Fujii, H; Ida, Y; Hanamura, S; Osa, Y; Nemoto, T; Nakajima, M; Hasebe, K; Nakao, K; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325527 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325527&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 49865682 117646848 CHEMBL1223774 ZINC58603896 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50593411 Cn1c(\C=C\C(=O)c2ccccc2)cc2C[C@@]3(O)[C@H]4Cc5ccc(O)c6O[C@@H](c12)[C@]3(CCN4CC1CC1)c56 InChI=1S/C32H32N2O4/c1-33-23(10-12-24(35)20-5-3-2-4-6-20)15-22-17-32(37)26-16-21-9-11-25(36)29-27(21)31(32,30(38-29)28(22)33)13-14-34(26)18-19-7-8-19/h2-6,9-12,15,19,26,30,36-37H,7-8,13-14,16-18H2,1H3/b12-10+/t26-,30+,31+,32-/m1/s1 QMCFOCBLALARSQ-UPHKCQIQSA-N 50325528 CHEMBL1223831 Mu-type opioid receptor Cavia cutleri 3.76 ChEMBL 10.1016/j.bmcl.2010.07.035 10.7270/Q2CJ8DPH 20685120 Fujii, H; Ida, Y; Hanamura, S; Osa, Y; Nemoto, T; Nakajima, M; Hasebe, K; Nakao, K; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325528 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325528&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 49865709 117646849 CHEMBL1223831 ZINC58591298 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50593412 Cc1occc1C(=O)C=Cc1cc2C[C@@]3(O)[C@H]4Cc5ccc(O)c6O[C@@H](c2n1C)[C@]3(CCN4CC1CC1)c56 InChI=1S/C31H32N2O5/c1-17-22(9-12-37-17)23(34)8-6-21-13-20-15-31(36)25-14-19-5-7-24(35)28-26(19)30(31,29(38-28)27(20)32(21)2)10-11-33(25)16-18-3-4-18/h5-9,12-13,18,25,29,35-36H,3-4,10-11,14-16H2,1-2H3/t25-,29+,30+,31-/m1/s1 SAYAGJKLQPFHAK-CBZTZNMZSA-N 50325529 CHEMBL1223832 Mu-type opioid receptor Cavia cutleri 6.2 ChEMBL 10.1016/j.bmcl.2010.07.035 10.7270/Q2CJ8DPH 20685120 Fujii, H; Ida, Y; Hanamura, S; Osa, Y; Nemoto, T; Nakajima, M; Hasebe, K; Nakao, K; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325529 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325529&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 49865710 117646850 CHEMBL1223832 ZINC58660410 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50593413 CCCCCC(=O)C=Cc1cc2C[C@@]3(O)[C@H]4Cc5ccc(O)c6O[C@@H](c2n1C)[C@]3(CCN4CC1CC1)c56 InChI=1S/C31H38N2O4/c1-3-4-5-6-23(34)11-10-22-15-21-17-31(36)25-16-20-9-12-24(35)28-26(20)30(31,29(37-28)27(21)32(22)2)13-14-33(25)18-19-7-8-19/h9-12,15,19,25,29,35-36H,3-8,13-14,16-18H2,1-2H3/t25-,29+,30+,31-/m1/s1 IDIQHUHLWUXDIK-CBZTZNMZSA-N 50325530 CHEMBL1223833 Mu-type opioid receptor Cavia cutleri 15 ChEMBL 10.1016/j.bmcl.2010.07.035 10.7270/Q2CJ8DPH 20685120 Fujii, H; Ida, Y; Hanamura, S; Osa, Y; Nemoto, T; Nakajima, M; Hasebe, K; Nakao, K; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325530 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325530&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 49865711 117646851 CHEMBL1223833 ZINC58591682 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50593414 Cn1c(CCC(=O)CCc2ccccc2)cc2C[C@@]3(O)[C@H]4Cc5ccc(O)c6O[C@@H](c12)[C@]3(CCN4CC1CC1)c56 InChI=1S/C34H38N2O4/c1-35-25(11-13-26(37)12-9-21-5-3-2-4-6-21)17-24-19-34(39)28-18-23-10-14-27(38)31-29(23)33(34,32(40-31)30(24)35)15-16-36(28)20-22-7-8-22/h2-6,10,14,17,22,28,32,38-39H,7-9,11-13,15-16,18-20H2,1H3/t28-,32+,33+,34-/m1/s1 OGVWUHCMHGUMDN-XZLGBSMGSA-N 50325531 CHEMBL1223834 Mu-type opioid receptor Cavia cutleri 0.548 ChEMBL 10.1016/j.bmcl.2010.07.035 10.7270/Q2CJ8DPH 20685120 Fujii, H; Ida, Y; Hanamura, S; Osa, Y; Nemoto, T; Nakajima, M; Hasebe, K; Nakao, K; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325531 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325531&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 49865712 117646852 CHEMBL1223834 ZINC58591348 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50593415 Cn1c(\C=C\c2ccccc2)cc2C[C@@]3(O)[C@H]4Cc5ccc(O)c6O[C@@H](c12)[C@]3(CCN4CC1CC1)c56 InChI=1S/C31H32N2O3/c1-32-23(11-9-19-5-3-2-4-6-19)15-22-17-31(35)25-16-21-10-12-24(34)28-26(21)30(31,29(36-28)27(22)32)13-14-33(25)18-20-7-8-20/h2-6,9-12,15,20,25,29,34-35H,7-8,13-14,16-18H2,1H3/b11-9+/t25-,29+,30+,31-/m1/s1 JDKCNLGYDYUAKT-IGCHYWFRSA-N 50325532 CHEMBL1223889 Mu-type opioid receptor Cavia cutleri 1.76 ChEMBL 10.1016/j.bmcl.2010.07.035 10.7270/Q2CJ8DPH 20685120 Fujii, H; Ida, Y; Hanamura, S; Osa, Y; Nemoto, T; Nakajima, M; Hasebe, K; Nakao, K; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325532 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325532&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 49865740 117646853 CHEMBL1223889 ZINC58591212 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50593416 CCC\C=C\c1cc2C[C@@]3(O)[C@H]4Cc5ccc(O)c6O[C@@H](c2n1C)[C@]3(CCN4CC1CC1)c56 InChI=1S/C28H34N2O3/c1-3-4-5-6-20-13-19-15-28(32)22-14-18-9-10-21(31)25-23(18)27(28,26(33-25)24(19)29(20)2)11-12-30(22)16-17-7-8-17/h5-6,9-10,13,17,22,26,31-32H,3-4,7-8,11-12,14-16H2,1-2H3/b6-5+/t22-,26+,27+,28-/m1/s1 BXWAUTPVMVQUIZ-VILXQWKCSA-N 50325533 CHEMBL1223890 Mu-type opioid receptor Cavia cutleri 5.85 ChEMBL 10.1016/j.bmcl.2010.07.035 10.7270/Q2CJ8DPH 20685120 Fujii, H; Ida, Y; Hanamura, S; Osa, Y; Nemoto, T; Nakajima, M; Hasebe, K; Nakao, K; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325533 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325533&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 49865741 117646854 CHEMBL1223890 ZINC58576419 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50622838 CN([C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45)C(=O)\C=C\c1ccoc1 InChI=1S/C28H32N2O5/c1-29(23(32)7-4-18-9-13-34-16-18)20-8-10-28(33)22-14-19-5-6-21(31)25-24(19)27(28,26(20)35-25)11-12-30(22)15-17-2-3-17/h4-7,9,13,16-17,20,22,26,31,33H,2-3,8,10-12,14-15H2,1H3/b7-4+/t20-,22-,26+,27+,28-/m1/s1 XGZZHZMWIXFATA-UEZBDDGYSA-N 50325534 CHEMBL267495::nalfurafine Mu-type opioid receptor Cavia cutleri 0.582 ChEMBL 10.1016/j.bmc.2010.12.035 10.7270/Q23N23P2 21256034 Nemoto, T; Yamamoto, N; Watanabe, A; Fujii, H; Hasebe, K; Nakajima, M; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325534&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search IVB 7YIT 6445230 117646855 CHEMBL267495 1651 ZINC04393014 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50622839 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2[C@@H]4Oc6c7c(C[C@H]8N(CC9CC9)CC[C@@]47[C@@]8(O)Cc2c1C[C@@]35O)ccc6O InChI=1S/C40H43N3O6/c44-25-7-5-21-13-27-39(46)15-23-24-16-40(47)28-14-22-6-8-26(45)34-30(22)38(40,10-12-43(28)18-20-3-4-20)36(49-34)32(24)41-31(23)35-37(39,29(21)33(25)48-35)9-11-42(27)17-19-1-2-19/h5-8,19-20,27-28,35-36,41,44-47H,1-4,9-18H2/t27-,28-,35+,36+,37+,38+,39-,40-/m1/s1 APSUXPSYBJVPPS-YAUKWVCOSA-N 82551 C18130::CAS_105618-26-6::NOR-BNI (HCI)2::NORBNI Mu-type opioid receptor Cavia cutleri 28.2 ChEMBL 10.1016/j.bmc.2010.12.035 10.7270/Q23N23P2 21256034 Nemoto, T; Yamamoto, N; Watanabe, A; Fujii, H; Hasebe, K; Nakajima, M; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82551&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5480230 136350521 C18130 ZINC03995590 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50622840 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]4(C[C@]5(CNC(=O)c6ccccc6)CC[C@@]34O5)c2c1 InChI=1S/C28H32N2O3/c31-22-9-8-21-14-24-28-11-10-26(33-28,18-29-25(32)20-4-2-1-3-5-20)17-27(28,23(21)15-22)12-13-30(24)16-19-6-7-19/h1-5,8-9,15,19,24,31H,6-7,10-14,16-18H2,(H,29,32)/t24-,26+,27-,28-/m1/s1 XFDJCAOJNOATOO-KCPYNUOSSA-N 50336661 CHEMBL1672475::N-{[(1R,9R,10S,13S)-17-(cyclopropylmethyl)-4-hydroxy-18-oxa-17-azapentacyclo[7.5.3.1^{10,13}.0^{1,10}.0^{2,7}]octadeca-2(7),3,5-trien-13-yl]methyl}benzamide Mu-type opioid receptor Cavia cutleri 0.134 ChEMBL 10.1016/j.bmc.2010.12.035 10.7270/Q23N23P2 21256034 Nemoto, T; Yamamoto, N; Watanabe, A; Fujii, H; Hasebe, K; Nakajima, M; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336661 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336661&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 53324047 125086763 CHEMBL1672475 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50622841 CN(C[C@@]12CC[C@@]3(O1)[C@H]1Cc4ccc(O)cc4[C@]3(C2)CCN1CC1CC1)C(=O)c1ccccc1 InChI=1S/C29H34N2O3/c1-30(26(33)21-5-3-2-4-6-21)19-27-11-12-29(34-27)25-15-22-9-10-23(32)16-24(22)28(29,18-27)13-14-31(25)17-20-7-8-20/h2-6,9-10,16,20,25,32H,7-8,11-15,17-19H2,1H3/t25-,27+,28-,29-/m1/s1 VVJCVMDRMJXXII-KKAKYAENSA-N 50336662 CHEMBL1672474::N-[(17-Cyclopropylmethyl-6beta,14beta-epoxy-3-hydroxymorphinan-6alpha-yl)methyl]-N-methylbenzamide Mu-type opioid receptor Cavia cutleri 0.188 ChEMBL 10.1016/j.bmc.2010.12.035 10.7270/Q23N23P2 21256034 Nemoto, T; Yamamoto, N; Watanabe, A; Fujii, H; Hasebe, K; Nakajima, M; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336662 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336662&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 53325361 125086764 CHEMBL1672474 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50622842 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]4(C[C@]5(CNC(=O)Cc6ccccc6)CC[C@@]34O5)c2c1 InChI=1S/C29H34N2O3/c32-23-9-8-22-15-25-29-11-10-27(34-29,19-30-26(33)14-20-4-2-1-3-5-20)18-28(29,24(22)16-23)12-13-31(25)17-21-6-7-21/h1-5,8-9,16,21,25,32H,6-7,10-15,17-19H2,(H,30,33)/t25-,27+,28-,29-/m1/s1 RZKUOGDXPHAOGK-KKAKYAENSA-N 50336663 2-Phenyl-N-[(17-cyclopropylmethyl-6beta,14beta-epoxy-3-hydroxymorphinan-6alpha-yl)methyl]acetamide::CHEMBL1672471 Mu-type opioid receptor Cavia cutleri 0.132 ChEMBL 10.1016/j.bmc.2010.12.035 10.7270/Q23N23P2 21256034 Nemoto, T; Yamamoto, N; Watanabe, A; Fujii, H; Hasebe, K; Nakajima, M; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336663 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336663&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 53320079 125086765 CHEMBL1672471 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50622843 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]4(C[C@]5(CNC(=O)\C=C\c6ccoc6)CC[C@@]34O5)c2c1 InChI=1S/C28H32N2O4/c31-22-5-4-21-13-24-28-9-8-26(34-28,18-29-25(32)6-3-20-7-12-33-16-20)17-27(28,23(21)14-22)10-11-30(24)15-19-1-2-19/h3-7,12,14,16,19,24,31H,1-2,8-11,13,15,17-18H2,(H,29,32)/b6-3+/t24-,26+,27-,28-/m1/s1 OOGJTALKFMGUKL-IKWCYBDBSA-N 50336664 (2E)-N-[(17-Cyclopropylmethyl-6beta,14beta-epoxy-3-hydroxymorphinan-6alpha-yl)methyl]-(3-furyl)acrylamide::CHEMBL1672472 Mu-type opioid receptor Cavia cutleri 0.0828 ChEMBL 10.1016/j.bmc.2010.12.035 10.7270/Q23N23P2 21256034 Nemoto, T; Yamamoto, N; Watanabe, A; Fujii, H; Hasebe, K; Nakajima, M; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336664 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336664&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 53317480 125086766 CHEMBL1672472 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50622844 Cc1ccc(cc1)C(=O)NC[C@@]12CC[C@@]3(O1)[C@H]1Cc4ccc(O)cc4[C@]3(C2)CCN1CC1CC1 InChI=1S/C29H34N2O3/c1-19-2-6-21(7-3-19)26(33)30-18-27-10-11-29(34-27)25-14-22-8-9-23(32)15-24(22)28(29,17-27)12-13-31(25)16-20-4-5-20/h2-3,6-9,15,20,25,32H,4-5,10-14,16-18H2,1H3,(H,30,33)/t25-,27+,28-,29-/m1/s1 CZRALRYSYZFWKZ-KKAKYAENSA-N 50336665 CHEMBL1672469::N-[(17-Cyclopropylmethyl-6beta,14beta-epoxy-3-hydroxymorphinan-6alpha-yl)methyl]-4-methylbenzamide Mu-type opioid receptor Cavia cutleri 0.129 ChEMBL 10.1016/j.bmc.2010.12.035 10.7270/Q23N23P2 21256034 Nemoto, T; Yamamoto, N; Watanabe, A; Fujii, H; Hasebe, K; Nakajima, M; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336665 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336665&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 53325626 125086767 CHEMBL1672469 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50622845 Cc1cccc(c1)C(=O)NC[C@@]12CC[C@@]3(O1)[C@H]1Cc4ccc(O)cc4[C@]3(C2)CCN1CC1CC1 InChI=1S/C29H34N2O3/c1-19-3-2-4-22(13-19)26(33)30-18-27-9-10-29(34-27)25-14-21-7-8-23(32)15-24(21)28(29,17-27)11-12-31(25)16-20-5-6-20/h2-4,7-8,13,15,20,25,32H,5-6,9-12,14,16-18H2,1H3,(H,30,33)/t25-,27+,28-,29-/m1/s1 YXGPVAPCDIGKQE-KKAKYAENSA-N 50336666 CHEMBL1672468::N-[(17-Cyclopropylmethyl-6beta,14beta-epoxy-3-hydroxymorphinan-6alpha-yl)methyl]-3-methylbenzamide Mu-type opioid receptor Cavia cutleri 0.156 ChEMBL 10.1016/j.bmc.2010.12.035 10.7270/Q23N23P2 21256034 Nemoto, T; Yamamoto, N; Watanabe, A; Fujii, H; Hasebe, K; Nakajima, M; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336666 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336666&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 53320078 125086768 CHEMBL1672468 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50622846 Cc1ccccc1C(=O)NC[C@@]12CC[C@@]3(O1)[C@H]1Cc4ccc(O)cc4[C@]3(C2)CCN1CC1CC1 InChI=1S/C29H34N2O3/c1-19-4-2-3-5-23(19)26(33)30-18-27-10-11-29(34-27)25-14-21-8-9-22(32)15-24(21)28(29,17-27)12-13-31(25)16-20-6-7-20/h2-5,8-9,15,20,25,32H,6-7,10-14,16-18H2,1H3,(H,30,33)/t25-,27+,28-,29-/m1/s1 FXMOFUZAQBXAET-KKAKYAENSA-N 50336667 CHEMBL1672470::N-[(17-Cyclopropylmethyl-6beta,14beta-epoxy-3-hydroxymorphinan-6alpha-yl)methyl]-2-methylbenzamide Mu-type opioid receptor Cavia cutleri 0.109 ChEMBL 10.1016/j.bmc.2010.12.035 10.7270/Q23N23P2 21256034 Nemoto, T; Yamamoto, N; Watanabe, A; Fujii, H; Hasebe, K; Nakajima, M; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336667 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336667&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 53325360 125086769 CHEMBL1672470 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50622847 CN(C[C@@]12CC[C@@]3(O1)[C@H]1Cc4ccc(O)cc4[C@]3(C2)CCN1CC1CC1)C(=O)c1ccc(C)cc1 InChI=1S/C30H36N2O3/c1-20-3-7-22(8-4-20)27(34)31(2)19-28-11-12-30(35-28)26-15-23-9-10-24(33)16-25(23)29(30,18-28)13-14-32(26)17-21-5-6-21/h3-4,7-10,16,21,26,33H,5-6,11-15,17-19H2,1-2H3/t26-,28+,29-,30-/m1/s1 OBYUGIUWLOIQCY-RRFVUZEHSA-N 50336668 CHEMBL1672476::N-[(17-Cyclopropylmethyl-6beta,14beta-epoxy-3-hydroxymorphinan-6alpha-yl)methyl]-N,4-dimethylbenzamide Mu-type opioid receptor Cavia cutleri 0.27 ChEMBL 10.1016/j.bmc.2010.12.035 10.7270/Q23N23P2 21256034 Nemoto, T; Yamamoto, N; Watanabe, A; Fujii, H; Hasebe, K; Nakajima, M; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336668 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336668&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 53322706 125086770 CHEMBL1672476 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50622848 CN1CC[C@]23C[C@]4(CNC(=O)c5ccccc5)CC[C@@]2(O4)[C@H]1Cc1ccc(O)cc31 InChI=1S/C25H28N2O3/c1-27-12-11-24-15-23(16-26-22(29)17-5-3-2-4-6-17)9-10-25(24,30-23)21(27)13-18-7-8-19(28)14-20(18)24/h2-8,14,21,28H,9-13,15-16H2,1H3,(H,26,29)/t21-,23+,24-,25-/m1/s1 WRWLOQYQGLYXSV-RVFVQDDPSA-N 50336669 CHEMBL1672477::N-[(6beta,14beta-Epoxy-3-hydroxy-17-methylmorphinan-6alpha-yl)methyl]benzamide Mu-type opioid receptor Cavia cutleri 0.0522 ChEMBL 10.1016/j.bmc.2010.12.035 10.7270/Q23N23P2 21256034 Nemoto, T; Yamamoto, N; Watanabe, A; Fujii, H; Hasebe, K; Nakajima, M; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336669 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336669&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 53325362 125086771 CHEMBL1672477 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50622849 CC(C)CN1CC[C@]23C[C@]4(CNC(=O)c5ccccc5)CC[C@@]2(O4)[C@H]1Cc1ccc(O)cc31 InChI=1S/C28H34N2O3/c1-19(2)16-30-13-12-27-17-26(18-29-25(32)20-6-4-3-5-7-20)10-11-28(27,33-26)24(30)14-21-8-9-22(31)15-23(21)27/h3-9,15,19,24,31H,10-14,16-18H2,1-2H3,(H,29,32)/t24-,26+,27-,28-/m1/s1 DDCBQLSLHHVDKR-KCPYNUOSSA-N 50336670 CHEMBL1672478::N-[(6beta,14beta-Epoxy-3-hydroxy-17-isobutylmorphinan-6alpha-yl)methyl]benzamide Mu-type opioid receptor Cavia cutleri 0.29 ChEMBL 10.1016/j.bmc.2010.12.035 10.7270/Q23N23P2 21256034 Nemoto, T; Yamamoto, N; Watanabe, A; Fujii, H; Hasebe, K; Nakajima, M; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336670 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336670&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 53317481 125086772 CHEMBL1672478 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50622850 Oc1ccc(cc1)C(=O)NC[C@@]12CC[C@@]3(O1)[C@H]1Cc4ccc(O)cc4[C@]3(C2)CCN1CC1CC1 InChI=1S/C28H32N2O4/c31-21-6-3-19(4-7-21)25(33)29-17-26-9-10-28(34-26)24-13-20-5-8-22(32)14-23(20)27(28,16-26)11-12-30(24)15-18-1-2-18/h3-8,14,18,24,31-32H,1-2,9-13,15-17H2,(H,29,33)/t24-,26+,27-,28-/m1/s1 SWUIDRZSWCFQCC-KCPYNUOSSA-N 50336671 CHEMBL1672479::N-[(17-Cyclopropylmethyl-6beta,14beta-epoxy-3-hydroxymorphinan-6alpha-yl)methyl]-4-hydroxybenzamide Mu-type opioid receptor Cavia cutleri 0.12 ChEMBL 10.1016/j.bmc.2010.12.035 10.7270/Q23N23P2 21256034 Nemoto, T; Yamamoto, N; Watanabe, A; Fujii, H; Hasebe, K; Nakajima, M; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336671 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336671&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 53326608 125086773 CHEMBL1672479 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50622851 Oc1cccc(c1)C(=O)NC[C@@]12CC[C@@]3(O1)[C@H]1Cc4ccc(O)cc4[C@]3(C2)CCN1CC1CC1 InChI=1S/C28H32N2O4/c31-21-3-1-2-20(12-21)25(33)29-17-26-8-9-28(34-26)24-13-19-6-7-22(32)14-23(19)27(28,16-26)10-11-30(24)15-18-4-5-18/h1-3,6-7,12,14,18,24,31-32H,4-5,8-11,13,15-17H2,(H,29,33)/t24-,26+,27-,28-/m1/s1 BUGIPTHAYUEMRB-KCPYNUOSSA-N 50336672 CHEMBL1672473::N-[(17-Cyclopropylmethyl-6beta,14beta-epoxy-3-hydroxymorphinan-6alpha-yl)methyl]-3-hydroxybenzamide Mu-type opioid receptor Cavia cutleri 0.121 ChEMBL 10.1016/j.bmc.2010.12.035 10.7270/Q23N23P2 21256034 Nemoto, T; Yamamoto, N; Watanabe, A; Fujii, H; Hasebe, K; Nakajima, M; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336672 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336672&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 53326607 125086774 CHEMBL1672473 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50622852 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]4(C[C@]5(CNC(=O)c6ccccc6O)CC[C@@]34O5)c2c1 InChI=1S/C28H32N2O4/c31-20-8-7-19-13-24-28-10-9-26(34-28,17-29-25(33)21-3-1-2-4-23(21)32)16-27(28,22(19)14-20)11-12-30(24)15-18-5-6-18/h1-4,7-8,14,18,24,31-32H,5-6,9-13,15-17H2,(H,29,33)/t24-,26+,27-,28-/m1/s1 HJQFVZZYCZJRIA-KCPYNUOSSA-N 50336673 CHEMBL1672480::N-[(17-Cyclopropylmethyl-6beta,14beta-epoxy-3-hydroxymorphinan-6alpha-yl)methyl]-2-hydroxybenzamide Mu-type opioid receptor Cavia cutleri 0.147 ChEMBL 10.1016/j.bmc.2010.12.035 10.7270/Q23N23P2 21256034 Nemoto, T; Yamamoto, N; Watanabe, A; Fujii, H; Hasebe, K; Nakajima, M; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336673 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336673&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 53322987 125086775 CHEMBL1672480 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50622853 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]4(C[C@]5(CNC(=O)c6cccc(F)c6)CC[C@@]34O5)c2c1 InChI=1S/C28H31FN2O3/c29-21-3-1-2-20(12-21)25(33)30-17-26-8-9-28(34-26)24-13-19-6-7-22(32)14-23(19)27(28,16-26)10-11-31(24)15-18-4-5-18/h1-3,6-7,12,14,18,24,32H,4-5,8-11,13,15-17H2,(H,30,33)/t24-,26+,27-,28-/m1/s1 OJCXMVRJVNDHHZ-KCPYNUOSSA-N 50336674 CHEMBL1672481::N-[(17-Cyclopropylmethyl-6beta,14beta-epoxy-3-hydroxymorphinan-6alpha-yl)methyl]-3-fluorobenzamide Mu-type opioid receptor Cavia cutleri 0.11 ChEMBL 10.1016/j.bmc.2010.12.035 10.7270/Q23N23P2 21256034 Nemoto, T; Yamamoto, N; Watanabe, A; Fujii, H; Hasebe, K; Nakajima, M; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336674 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336674&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 53320139 125086776 CHEMBL1672481 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50622854 Oc1ccc2C[C@H]3N(Cc4ccccc4)CC[C@@]4(C[C@]5(CNC(=O)c6ccccc6)CC[C@@]34O5)c2c1 InChI=1S/C31H32N2O3/c34-25-12-11-24-17-27-31-14-13-29(36-31,21-32-28(35)23-9-5-2-6-10-23)20-30(31,26(24)18-25)15-16-33(27)19-22-7-3-1-4-8-22/h1-12,18,27,34H,13-17,19-21H2,(H,32,35)/t27-,29+,30-,31-/m1/s1 FWWQWLYQWDGCKU-GEIIOTBESA-N 50336675 CHEMBL1672482::N-[(17-Benzyl-6beta,14beta-epoxy-3-hydroxymorphinan-6alpha-yl)methyl]benzamide Mu-type opioid receptor Cavia cutleri 4.38 ChEMBL 10.1016/j.bmc.2010.12.035 10.7270/Q23N23P2 21256034 Nemoto, T; Yamamoto, N; Watanabe, A; Fujii, H; Hasebe, K; Nakajima, M; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336675 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336675&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 53322707 125086777 CHEMBL1672482 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50622855 Oc1ccc2C[C@H]3N(CCc4ccccc4)CC[C@@]4(C[C@]5(CNC(=O)c6ccccc6)CC[C@@]34O5)c2c1 InChI=1S/C32H34N2O3/c35-26-12-11-25-19-28-32-15-14-30(37-32,22-33-29(36)24-9-5-2-6-10-24)21-31(32,27(25)20-26)16-18-34(28)17-13-23-7-3-1-4-8-23/h1-12,20,28,35H,13-19,21-22H2,(H,33,36)/t28-,30+,31-,32-/m1/s1 BNLKNBFOHOWIDK-IMRLWEKHSA-N 50336676 CHEMBL1672483::N-[(6beta,14beta-Epoxy-3-hydroxy-17-phenethylmorphinan-6alpa-yl)methyl]benzamide Mu-type opioid receptor Cavia cutleri 0.243 ChEMBL 10.1016/j.bmc.2010.12.035 10.7270/Q23N23P2 21256034 Nemoto, T; Yamamoto, N; Watanabe, A; Fujii, H; Hasebe, K; Nakajima, M; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336676 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336676&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 53318759 125086778 CHEMBL1672483 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50622856 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]4(C[C@]5(CNC(=O)CCc6ccccc6)CC[C@@]34O5)c2c1 InChI=1S/C30H36N2O3/c33-24-10-9-23-16-26-30-13-12-28(35-30,20-31-27(34)11-8-21-4-2-1-3-5-21)19-29(30,25(23)17-24)14-15-32(26)18-22-6-7-22/h1-5,9-10,17,22,26,33H,6-8,11-16,18-20H2,(H,31,34)/t26-,28+,29-,30-/m1/s1 SMRRQSWDCMZHIM-RRFVUZEHSA-N 50336677 CHEMBL1672484::N-[(17-Cyclopropylmethyl-6beta,14beta-epoxy-3-hydroxymorphinan-6alpha-yl)methyl]-3-phenylpropionamide Mu-type opioid receptor Cavia cutleri 0.182 ChEMBL 10.1016/j.bmc.2010.12.035 10.7270/Q23N23P2 21256034 Nemoto, T; Yamamoto, N; Watanabe, A; Fujii, H; Hasebe, K; Nakajima, M; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336677 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336677&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 53320080 125086779 CHEMBL1672484 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50622857 CC(C)CN1CC[C@]23C[C@]4(CNC(=O)c5ccc(O)cc5)CC[C@@]2(O4)[C@H]1Cc1ccc(O)cc31 InChI=1S/C28H34N2O4/c1-18(2)15-30-12-11-27-16-26(17-29-25(33)19-3-6-21(31)7-4-19)9-10-28(27,34-26)24(30)13-20-5-8-22(32)14-23(20)27/h3-8,14,18,24,31-32H,9-13,15-17H2,1-2H3,(H,29,33)/t24-,26+,27-,28-/m1/s1 FPCYKXLKCLRVDY-KCPYNUOSSA-N 50336678 CHEMBL1672485::N-[(6beta,14beta-Epoxy-3-hydroxy-17-isobutylmorphinan-6alpha-yl)methyl]-4-hydroxybenzamide Mu-type opioid receptor Cavia cutleri 0.946 ChEMBL 10.1016/j.bmc.2010.12.035 10.7270/Q23N23P2 21256034 Nemoto, T; Yamamoto, N; Watanabe, A; Fujii, H; Hasebe, K; Nakajima, M; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336678 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336678&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 53324048 125086780 CHEMBL1672485 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50622858 CC(C)CN1CC[C@]23C[C@]4(CNC(=O)c5cccc(O)c5)CC[C@@]2(O4)[C@H]1Cc1ccc(O)cc31 InChI=1S/C28H34N2O4/c1-18(2)15-30-11-10-27-16-26(17-29-25(33)20-4-3-5-21(31)12-20)8-9-28(27,34-26)24(30)13-19-6-7-22(32)14-23(19)27/h3-7,12,14,18,24,31-32H,8-11,13,15-17H2,1-2H3,(H,29,33)/t24-,26+,27-,28-/m1/s1 NSSDYIOVXJRNLM-KCPYNUOSSA-N 50336679 CHEMBL1672486::N-[(6beta,14beta-Epoxy-3-hydroxy-17-isobutylmorphinan-6alpha-yl)methyl]-3-hydroxybenzamide Mu-type opioid receptor Cavia cutleri 0.389 ChEMBL 10.1016/j.bmc.2010.12.035 10.7270/Q23N23P2 21256034 Nemoto, T; Yamamoto, N; Watanabe, A; Fujii, H; Hasebe, K; Nakajima, M; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336679 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336679&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 53317482 125086781 CHEMBL1672486 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50622859 CC(C)CN1CC[C@]23C[C@]4(CNC(=O)c5ccccc5O)CC[C@@]2(O4)[C@H]1Cc1ccc(O)cc31 InChI=1S/C28H34N2O4/c1-18(2)15-30-12-11-27-16-26(17-29-25(33)21-5-3-4-6-23(21)32)9-10-28(27,34-26)24(30)13-19-7-8-20(31)14-22(19)27/h3-8,14,18,24,31-32H,9-13,15-17H2,1-2H3,(H,29,33)/t24-,26+,27-,28-/m1/s1 VNCPGLMQKLYBIS-KCPYNUOSSA-N 50336680 CHEMBL1672487::N-[(6beta,14beta-Epoxy-3-hydroxy-17-isobutylmorphinan-6alpha-yl)methyl]-2-hydroxybenzamide Mu-type opioid receptor Cavia cutleri 0.466 ChEMBL 10.1016/j.bmc.2010.12.035 10.7270/Q23N23P2 21256034 Nemoto, T; Yamamoto, N; Watanabe, A; Fujii, H; Hasebe, K; Nakajima, M; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336680&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 53322708 125086782 CHEMBL1672487 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50622860 Oc1ccc(cc1)C(=O)NC[C@@]12CC[C@@]3(O1)[C@H]1Cc4ccc(O)cc4[C@]3(C2)CCN1Cc1ccccc1 InChI=1S/C31H32N2O4/c34-24-9-6-22(7-10-24)28(36)32-20-29-12-13-31(37-29)27-16-23-8-11-25(35)17-26(23)30(31,19-29)14-15-33(27)18-21-4-2-1-3-5-21/h1-11,17,27,34-35H,12-16,18-20H2,(H,32,36)/t27-,29+,30-,31-/m1/s1 SHODGJYIWBCOSN-GEIIOTBESA-N 50336681 CHEMBL1672488::N-[(17-benzyl-6beta,14beta-epoxy-3-hydroxymorphinan-6ayl)methyl]-4-hydroxybenzamide Mu-type opioid receptor Cavia cutleri 27.2 ChEMBL 10.1016/j.bmc.2010.12.035 10.7270/Q23N23P2 21256034 Nemoto, T; Yamamoto, N; Watanabe, A; Fujii, H; Hasebe, K; Nakajima, M; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336681 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336681&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 53320081 125086783 CHEMBL1672488 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50622861 Oc1ccc2C[C@H]3N(Cc4ccccc4)CC[C@@]4(C[C@]5(CNC(=O)c6ccccc6O)CC[C@@]34O5)c2c1 InChI=1S/C31H32N2O4/c34-23-11-10-22-16-27-31-13-12-29(37-31,20-32-28(36)24-8-4-5-9-26(24)35)19-30(31,25(22)17-23)14-15-33(27)18-21-6-2-1-3-7-21/h1-11,17,27,34-35H,12-16,18-20H2,(H,32,36)/t27-,29+,30-,31-/m1/s1 QBOVHOIAMXJUSJ-GEIIOTBESA-N 50336682 CHEMBL1672489::N-[(17-Benzyl-6beta,14beta-epoxy-3-hydroxymorphinan-6alpha-yl)methyl]-2-hydroxybenzamide Mu-type opioid receptor Cavia cutleri 17.4 ChEMBL 10.1016/j.bmc.2010.12.035 10.7270/Q23N23P2 21256034 Nemoto, T; Yamamoto, N; Watanabe, A; Fujii, H; Hasebe, K; Nakajima, M; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336682 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336682&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 53317483 125086784 CHEMBL1672489 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50622862 Oc1ccc2C[C@H]3N(CC4CCC4)CC[C@@]4(C[C@]5(CNC(=O)c6ccccc6)CC[C@@]34O5)c2c1 InChI=1S/C29H34N2O3/c32-23-10-9-22-15-25-29-12-11-27(34-29,19-30-26(33)21-7-2-1-3-8-21)18-28(29,24(22)16-23)13-14-31(25)17-20-5-4-6-20/h1-3,7-10,16,20,25,32H,4-6,11-15,17-19H2,(H,30,33)/t25-,27+,28-,29-/m1/s1 SCMAOCANZACXEE-KKAKYAENSA-N 50336683 CHEMBL1672490::N-[(17-Cyclobutylmethyl-6beta,14beta-epoxy-3-hydroxymorphinan-6alpha-yl)methyl]benzamide Mu-type opioid receptor Cavia cutleri 0.138 ChEMBL 10.1016/j.bmc.2010.12.035 10.7270/Q23N23P2 21256034 Nemoto, T; Yamamoto, N; Watanabe, A; Fujii, H; Hasebe, K; Nakajima, M; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336683&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 53326609 125086785 CHEMBL1672490 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50622863 Oc1cccc(c1)C(=O)NC[C@@]12CC[C@@]3(O1)[C@H]1Cc4ccc(O)cc4[C@]3(C2)CCN1Cc1ccccc1 InChI=1S/C31H32N2O4/c34-24-8-4-7-23(15-24)28(36)32-20-29-11-12-31(37-29)27-16-22-9-10-25(35)17-26(22)30(31,19-29)13-14-33(27)18-21-5-2-1-3-6-21/h1-10,15,17,27,34-35H,11-14,16,18-20H2,(H,32,36)/t27-,29+,30-,31-/m1/s1 SHZVLPMXDIIBRS-GEIIOTBESA-N 50336685 CHEMBL1672492::N-[(17-Benzyl-6beta,14beta-epoxy-3-hydroxymorphinan-6alpha-yl)methyl]-3-hydroxybenzamide Mu-type opioid receptor Cavia cutleri 18.3 ChEMBL 10.1016/j.bmc.2010.12.035 10.7270/Q23N23P2 21256034 Nemoto, T; Yamamoto, N; Watanabe, A; Fujii, H; Hasebe, K; Nakajima, M; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336685 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336685&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 53324049 125086787 CHEMBL1672492 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50622864 Oc1ccc2C[C@H]3N(Cc4ccccc4)CC[C@@]4(C[C@]5(CNC(=O)c6ccccc6F)CC[C@@]34O5)c2c1 InChI=1S/C31H31FN2O3/c32-26-9-5-4-8-24(26)28(36)33-20-29-12-13-31(37-29)27-16-22-10-11-23(35)17-25(22)30(31,19-29)14-15-34(27)18-21-6-2-1-3-7-21/h1-11,17,27,35H,12-16,18-20H2,(H,33,36)/t27-,29+,30-,31-/m1/s1 SLPPCIMDTAIRNZ-GEIIOTBESA-N 50336686 CHEMBL1672493::N-[(17-Benzyl-6beta,14beta-epoxy-3-hydroxymorphinan-6alpha-yl)methyl]-2-fluorobenzamide Mu-type opioid receptor Cavia cutleri 6.79 ChEMBL 10.1016/j.bmc.2010.12.035 10.7270/Q23N23P2 21256034 Nemoto, T; Yamamoto, N; Watanabe, A; Fujii, H; Hasebe, K; Nakajima, M; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336686&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 53317484 125086788 CHEMBL1672493 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50622865 Oc1ccc2C[C@H]3N(Cc4ccccc4)CC[C@@]4(C[C@]5(CNC(=O)c6cccc(F)c6)CC[C@@]34O5)c2c1 InChI=1S/C31H31FN2O3/c32-24-8-4-7-23(15-24)28(36)33-20-29-11-12-31(37-29)27-16-22-9-10-25(35)17-26(22)30(31,19-29)13-14-34(27)18-21-5-2-1-3-6-21/h1-10,15,17,27,35H,11-14,16,18-20H2,(H,33,36)/t27-,29+,30-,31-/m1/s1 XJMACFWLCBKWLL-GEIIOTBESA-N 50336687 CHEMBL1672494::N-[(17-Benzyl-6beta,14beta-epoxy-3-hydroxymorphinan-6alpha-yl)methyl]-3-fluorobenzamide Mu-type opioid receptor Cavia cutleri 1.35 ChEMBL 10.1016/j.bmc.2010.12.035 10.7270/Q23N23P2 21256034 Nemoto, T; Yamamoto, N; Watanabe, A; Fujii, H; Hasebe, K; Nakajima, M; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336687 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336687&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 53322709 125086789 CHEMBL1672494 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50622866 Oc1ccc2C[C@H]3N(Cc4ccccc4)CC[C@@]4(C[C@]5(CNC(=O)c6ccc(F)cc6)CC[C@@]34O5)c2c1 InChI=1S/C31H31FN2O3/c32-24-9-6-22(7-10-24)28(36)33-20-29-12-13-31(37-29)27-16-23-8-11-25(35)17-26(23)30(31,19-29)14-15-34(27)18-21-4-2-1-3-5-21/h1-11,17,27,35H,12-16,18-20H2,(H,33,36)/t27-,29+,30-,31-/m1/s1 YIGUCTLNPLDYPG-GEIIOTBESA-N 50336684 CHEMBL1672491::N-[(17-Benzyl-6beta,14beta-epoxy-3-hydroxymorphinan-6alpha-yl)methyl]-4-fluorobenzamide Mu-type opioid receptor Cavia cutleri 6.16 ChEMBL 10.1016/j.bmc.2010.12.035 10.7270/Q23N23P2 21256034 Nemoto, T; Yamamoto, N; Watanabe, A; Fujii, H; Hasebe, K; Nakajima, M; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336684 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336684&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 53320082 125086786 CHEMBL1672491 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50633569 CCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C62H76F6N10O9/c1-7-8-18-48(75-58(85)50(27-38-15-10-9-11-16-38)74-53(80)33-72-54(81)37(6)73-55(82)46(69)30-45-35(4)23-43(79)24-36(45)5)60(87)78-21-14-20-52(78)59(86)77-49(22-34(2)3)57(84)76-51(28-40-32-70-47-19-13-12-17-44(40)47)56(83)71-31-39-25-41(61(63,64)65)29-42(26-39)62(66,67)68/h9-13,15-17,19,23-26,29,32,34,37,46,48-52,70,79H,7-8,14,18,20-22,27-28,30-31,33,69H2,1-6H3,(H,71,83)(H,72,81)(H,73,82)(H,74,80)(H,75,85)(H,76,84)(H,77,86)/t37-,46+,48+,49+,50+,51+,52+/m1/s1 KTIXRTOVKASTTK-VQFZVEARSA-N 50341314 (S)-1-((2S,5S,11R,14S)-14-amino-5-benzyl-2-butyl-15-(4-hydroxy-2,6-dimethylphenyl)-11-methyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane)-N-((S)-1-((S)-1-(3,5-bis(trifluoromethyl)benzylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-4-methyl-1-oxopentan-2-yl)pyrrolidine-2-carboxamide::CHEMBL1766204 Mu-type opioid receptor Cavia cutleri 68 ChEMBL 10.1021/jm101023r 10.7270/Q2862GRK 21366266 Yamamoto, T; Nair, P; Largent-Milnes, TM; Jacobsen, NE; Davis, P; Ma, SW; Yamamura, HI; Vanderah, TW; Porreca, F; Lai, J; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341314&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44177570 131344250 CHEMBL1766204 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50633570 CCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N(C)Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C63H78F6N10O9/c1-8-9-19-49(75-58(85)51(28-39-16-11-10-12-17-39)74-54(81)33-72-55(82)38(6)73-56(83)47(70)31-46-36(4)24-44(80)25-37(46)5)61(88)79-22-15-21-53(79)59(86)76-50(23-35(2)3)57(84)77-52(29-41-32-71-48-20-14-13-18-45(41)48)60(87)78(7)34-40-26-42(62(64,65)66)30-43(27-40)63(67,68)69/h10-14,16-18,20,24-27,30,32,35,38,47,49-53,71,80H,8-9,15,19,21-23,28-29,31,33-34,70H2,1-7H3,(H,72,82)(H,73,83)(H,74,81)(H,75,85)(H,76,86)(H,77,84)/t38-,47+,49+,50+,51+,52+,53+/m1/s1 TURPYQHVJSEIHN-BAZFYLPPSA-N 50341315 (S)-1-((2S,5S,11R,14S)-14-amino-5-benzyl-2-butyl-15-(4-hydroxy-2,6-dimethylphenyl)-11-methyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane)-N-((S)-1-((S)-1-((3,5-bis(trifluoromethyl)benzyl)(methyl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-4-methyl-1-oxopentan-2-yl)pyrrolidine-2-carboxamide::CHEMBL1766205 Mu-type opioid receptor Cavia cutleri 110 ChEMBL 10.1021/jm101023r 10.7270/Q2862GRK 21366266 Yamamoto, T; Nair, P; Largent-Milnes, TM; Jacobsen, NE; Davis, P; Ma, SW; Yamamura, HI; Vanderah, TW; Porreca, F; Lai, J; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341315 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341315&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44177669 131344251 CHEMBL1766205 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50633571 CCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1cccc(c1)C(F)(F)F InChI=1S/C61H77F3N10O9/c1-7-8-21-48(71-58(81)50(29-39-16-10-9-11-17-39)70-53(76)34-68-54(77)38(6)69-55(78)46(65)31-45-36(4)26-43(75)27-37(45)5)60(83)74-24-15-23-52(74)59(82)73-49(25-35(2)3)57(80)72-51(30-41-33-66-47-22-13-12-20-44(41)47)56(79)67-32-40-18-14-19-42(28-40)61(62,63)64/h9-14,16-20,22,26-28,33,35,38,46,48-52,66,75H,7-8,15,21,23-25,29-32,34,65H2,1-6H3,(H,67,79)(H,68,77)(H,69,78)(H,70,76)(H,71,81)(H,72,80)(H,73,82)/t38-,46+,48+,49+,50+,51+,52+/m1/s1 DDUYZUHEHGIESX-KOKNPPTNSA-N 50341316 (S)-N-((S)-1-((S)-3-(1H-indol-3-yl)-1-oxo-1-(3-(trifluoromethyl)benzylamino)propan-2-ylamino)-4-methyl-1-oxopentan-2-yl)-1-((2S,5S,11R,14S)-14-amino-5-benzyl-2-butyl-15-(4-hydroxy-2,6-dimethylphenyl)-11-methyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane)pyrrolidine-2-carboxamide::CHEMBL1766206 Mu-type opioid receptor Cavia cutleri 22 ChEMBL 10.1021/jm101023r 10.7270/Q2862GRK 21366266 Yamamoto, T; Nair, P; Largent-Milnes, TM; Jacobsen, NE; Davis, P; Ma, SW; Yamamura, HI; Vanderah, TW; Porreca, F; Lai, J; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341316 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341316&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44177670 131344252 CHEMBL1766206 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50633572 CCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1ccc(OC)c(OC)c1 InChI=1S/C62H82N10O11/c1-9-10-20-48(69-60(79)50(29-40-17-12-11-13-18-40)68-55(74)35-66-56(75)39(6)67-57(76)46(63)32-45-37(4)27-43(73)28-38(45)5)62(81)72-25-16-22-52(72)61(80)71-49(26-36(2)3)59(78)70-51(31-42-34-64-47-21-15-14-19-44(42)47)58(77)65-33-41-23-24-53(82-7)54(30-41)83-8/h11-15,17-19,21,23-24,27-28,30,34,36,39,46,48-52,64,73H,9-10,16,20,22,25-26,29,31-33,35,63H2,1-8H3,(H,65,77)(H,66,75)(H,67,76)(H,68,74)(H,69,79)(H,70,78)(H,71,80)/t39-,46+,48+,49+,50+,51+,52+/m1/s1 NOIBJKOGTIRXOG-CDKLIATISA-N 50341317 (S)-1-((2S,5S,11R,14S)-14-amino-5-benzyl-2-butyl-15-(4-hydroxy-2,6-dimethylphenyl)-11-methyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane)-N-((S)-1-((S)-1-(3,4-dimethoxybenzylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-4-methyl-1-oxopentan-2-yl)pyrrolidine-2-carboxamide::CHEMBL1766207 Mu-type opioid receptor Cavia cutleri 23 ChEMBL 10.1021/jm101023r 10.7270/Q2862GRK 21366266 Yamamoto, T; Nair, P; Largent-Milnes, TM; Jacobsen, NE; Davis, P; Ma, SW; Yamamura, HI; Vanderah, TW; Porreca, F; Lai, J; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341317 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341317&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 54581461 131344253 CHEMBL1766207 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50633573 CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C61H74F6N10O9S/c1-33(2)21-48(56(83)75-50(27-39-31-69-46-16-11-10-15-43(39)46)55(82)70-30-38-24-40(60(62,63)64)28-41(25-38)61(65,66)67)76-58(85)51-17-12-19-77(51)59(86)47(18-20-87-6)74-57(84)49(26-37-13-8-7-9-14-37)73-52(79)32-71-53(80)36(5)72-54(81)45(68)29-44-34(3)22-42(78)23-35(44)4/h7-11,13-16,22-25,28,31,33,36,45,47-51,69,78H,12,17-21,26-27,29-30,32,68H2,1-6H3,(H,70,82)(H,71,80)(H,72,81)(H,73,79)(H,74,84)(H,75,83)(H,76,85)/t36-,45+,47+,48+,49+,50+,51+/m1/s1 ATJZNASWBNGJGA-UPKFDLETSA-N 50341318 (S)-1-((2S,5S,11R,14S)-14-amino-5-benzyl-15-(4-hydroxy-2,6-dimethylphenyl)-11-methyl-2-(2-(methylthio)ethyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane)-N-((S)-1-((S)-1-(3,5-bis(trifluoromethyl)benzylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-4-methyl-1-oxopentan-2-yl)pyrrolidine-2-carboxamide::CHEMBL1766208 Mu-type opioid receptor Cavia cutleri 19 ChEMBL 10.1021/jm101023r 10.7270/Q2862GRK 21366266 Yamamoto, T; Nair, P; Largent-Milnes, TM; Jacobsen, NE; Davis, P; Ma, SW; Yamamura, HI; Vanderah, TW; Porreca, F; Lai, J; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341318 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341318&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44178113 131344254 CHEMBL1766208 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50633574 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C46H56N10O10/c1-27(51-43(63)35(47)21-31-13-17-33(57)18-14-31)41(61)49-25-39(59)53-37(23-29-9-5-3-6-10-29)45(65)55-56-46(66)38(24-30-11-7-4-8-12-30)54-40(60)26-50-42(62)28(2)52-44(64)36(48)22-32-15-19-34(58)20-16-32/h3-20,27-28,35-38,57-58H,21-26,47-48H2,1-2H3,(H,49,61)(H,50,62)(H,51,63)(H,52,64)(H,53,59)(H,54,60)(H,55,65)(H,56,66)/t27-,28-,35+,36+,37+,38+/m1/s1 DESSEGDLRYOPTJ-VRANXALZSA-N 21014 (2S)-2-amino-N-[(1R)-1-[({[(1S)-1-{N'-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanoyl]hydrazinecarbonyl}-2-phenylethyl]carbamoyl}methyl)carbamoyl]ethyl]-3-(4-hydroxyphenyl)propanamide::(Tyr-Ala-Gly-Phe-NH2)2::Biphalin::CHEMBL200199::bis(Tyr-Ala-Gly-PheNH2)hydrazide::enkephalin dimer Mu-type opioid receptor Cavia cutleri 8.8 ChEMBL 10.1021/jm101023r 10.7270/Q2862GRK 21366266 Yamamoto, T; Nair, P; Largent-Milnes, TM; Jacobsen, NE; Davis, P; Ma, SW; Yamamura, HI; Vanderah, TW; Porreca, F; Lai, J; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21014&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5487663 49689087 CHEMBL200199 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50645194 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H]1Cc2ccccc2CN(CC(N)=O)C1=O InChI=1S/C29H40N8O5/c1-16-10-20(38)11-17(2)21(16)13-22(30)26(40)35-23(8-5-9-34-29(32)33)27(41)36-24-12-18-6-3-4-7-19(18)14-37(28(24)42)15-25(31)39/h3-4,6-7,10-11,22-24,38H,5,8-9,12-15,30H2,1-2H3,(H2,31,39)(H,35,40)(H,36,41)(H4,32,33,34)/t22-,23+,24-/m0/s1 ORYLQLGPWPORPN-VXNXHJTFSA-N 50346330 (R)-N-((S)-2-(2-amino-2-oxoethyl)-3-oxo-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-yl)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)-5-guanidinopentanamide::CHEMBL1782140 Mu-type opioid receptor Cavia cutleri 0.32 ChEMBL 10.1021/jm1016285 10.7270/Q2416XD1 21413804 Ballet, S; Feytens, D; Buysse, K; Chung, NN; Lemieux, C; Tumati, S; Keresztes, A; Van Duppen, J; Lai, J; Varga, E; Porreca, F; Schiller, PW; Vanden Broeck, J; Tourwe, D Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346330&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 52937468 131349261 CHEMBL1782140 ZINC71295052 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50645195 CN(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)CN1Cc2ccccc2C[C@H](NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C1=O InChI=1S/C39H46F6N8O5/c1-21-11-28(54)12-22(2)29(21)17-30(46)34(56)50-31(9-6-10-49-37(47)48)35(57)51-32-15-24-7-4-5-8-25(24)19-53(36(32)58)20-33(55)52(3)18-23-13-26(38(40,41)42)16-27(14-23)39(43,44)45/h4-5,7-8,11-14,16,30-32,54H,6,9-10,15,17-20,46H2,1-3H3,(H,50,56)(H,51,57)(H4,47,48,49)/t30-,31+,32-/m0/s1 UXNDGPPTVKDIOD-QAXCHELISA-N 50346329 (R)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)-N-((S)-2-(2-((3,5-bis(trifluoromethyl)benzyl)(methyl)amino)-2-oxoethyl)-3-oxo-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-yl)-5-guanidinopentanamide::CHEMBL1782141 Mu-type opioid receptor Cavia cutleri 8.51 ChEMBL 10.1021/jm1016285 10.7270/Q2416XD1 21413804 Ballet, S; Feytens, D; Buysse, K; Chung, NN; Lemieux, C; Tumati, S; Keresztes, A; Van Duppen, J; Lai, J; Varga, E; Porreca, F; Schiller, PW; Vanden Broeck, J; Tourwe, D Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346329 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346329&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 52937467 131349260 CHEMBL1782141 ZINC95548072 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50645556 COC(=O)N1CC2C(CCCC1CN2C(=O)Cc1ccc(Cl)c(Cl)c1)N1CCCC1 InChI=1S/C22H29Cl2N3O3/c1-30-22(29)26-14-20-19(25-9-2-3-10-25)6-4-5-16(26)13-27(20)21(28)12-15-7-8-17(23)18(24)11-15/h7-8,11,16,19-20H,2-6,9-10,12-14H2,1H3 AXYUYAKZZNNKDG-UHFFFAOYSA-N 50346472 CHEMBL1782985::rel-(1RS,2RS,6SR)-methyl9-[2-(3,4-Dichlorophenyl)acetyl]-2-(pyrrolidin-1-yl)-7,9-diaza-bicyclo[4.2.2]decane-7-carboxylate::rel-(1RS,2SR,6SR)-methyl9-[2-(3,4-Dichlorophenyl)acetyl]-2-(pyrrolidin-1-yl)-7,9-diaza-bicyclo[4.2.2]decane-7-carboxylate Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1016/j.ejmech.2011.01.064 10.7270/Q2PV6KQ5 21481987 Sunnam, SK; Rack, E; Schepmann, D; Wunsch, B Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346472&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 54585192 131349403 CHEMBL1782985 ZINC71295719 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50645557 COC(=O)N1CC2C(CCCC1CN2C(=O)Cc1ccc(Cl)c(Cl)c1)N1CCCC1 InChI=1S/C22H29Cl2N3O3/c1-30-22(29)26-14-20-19(25-9-2-3-10-25)6-4-5-16(26)13-27(20)21(28)12-15-7-8-17(23)18(24)11-15/h7-8,11,16,19-20H,2-6,9-10,12-14H2,1H3 AXYUYAKZZNNKDG-UHFFFAOYSA-N 50346472 CHEMBL1782985::rel-(1RS,2RS,6SR)-methyl9-[2-(3,4-Dichlorophenyl)acetyl]-2-(pyrrolidin-1-yl)-7,9-diaza-bicyclo[4.2.2]decane-7-carboxylate::rel-(1RS,2SR,6SR)-methyl9-[2-(3,4-Dichlorophenyl)acetyl]-2-(pyrrolidin-1-yl)-7,9-diaza-bicyclo[4.2.2]decane-7-carboxylate Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1016/j.ejmech.2011.01.064 10.7270/Q2PV6KQ5 21481987 Sunnam, SK; Rack, E; Schepmann, D; Wunsch, B Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346472&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 54585192 131349403 CHEMBL1782985 ZINC71295719 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50645558 Clc1ccc(CC(=O)N2CC3CCCC(C2CN3Cc2ccccc2)N2CCCC2)cc1Cl InChI=1S/C27H33Cl2N3O/c28-23-12-11-21(15-24(23)29)16-27(33)32-18-22-9-6-10-25(30-13-4-5-14-30)26(32)19-31(22)17-20-7-2-1-3-8-20/h1-3,7-8,11-12,15,22,25-26H,4-6,9-10,13-14,16-19H2 XSQRHBCVIUUUJP-UHFFFAOYSA-N 50346473 CHEMBL1782987::rel-(1RS,2RS,6SR)-7-benzyl-9-[2-(3,4-dichlorophenyl)acetyl]-2-(pyrrolidin-1-yl)-7,9-diaza-bicyclo[4.2.2]decane::rel-(1RS,2SR,6SR)-7-benzyl-9-[2-(3,4-dichlorophenyl)acetyl]-2-(pyrrolidin-1-yl)-7,9-diazabicyclo[4.2.2]decane Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1016/j.ejmech.2011.01.064 10.7270/Q2PV6KQ5 21481987 Sunnam, SK; Rack, E; Schepmann, D; Wunsch, B Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346473&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 54584226 131349404 CHEMBL1782987 ZINC71294463 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50645559 Clc1ccc(CC(=O)N2CC3CCCC(C2CN3Cc2ccccc2)N2CCCC2)cc1Cl InChI=1S/C27H33Cl2N3O/c28-23-12-11-21(15-24(23)29)16-27(33)32-18-22-9-6-10-25(30-13-4-5-14-30)26(32)19-31(22)17-20-7-2-1-3-8-20/h1-3,7-8,11-12,15,22,25-26H,4-6,9-10,13-14,16-19H2 XSQRHBCVIUUUJP-UHFFFAOYSA-N 50346473 CHEMBL1782987::rel-(1RS,2RS,6SR)-7-benzyl-9-[2-(3,4-dichlorophenyl)acetyl]-2-(pyrrolidin-1-yl)-7,9-diaza-bicyclo[4.2.2]decane::rel-(1RS,2SR,6SR)-7-benzyl-9-[2-(3,4-dichlorophenyl)acetyl]-2-(pyrrolidin-1-yl)-7,9-diazabicyclo[4.2.2]decane Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1016/j.ejmech.2011.01.064 10.7270/Q2PV6KQ5 21481987 Sunnam, SK; Rack, E; Schepmann, D; Wunsch, B Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346473&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 54584226 131349404 CHEMBL1782987 ZINC71294463 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50645571 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 2.2 ChEMBL 10.1016/j.ejmech.2011.01.064 10.7270/Q2PV6KQ5 21481987 Sunnam, SK; Rack, E; Schepmann, D; Wunsch, B Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50646860 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 1.98 ChEMBL 10.1016/j.bmcl.2011.04.134 10.7270/Q2D79BR5 21641219 Nagase, H; Watanabe, A; Nemoto, T; Nakajima, M; Hasebe, K; Mochizuki, H; Fujii, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50646862 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@]1(CC[C@@]35O)O[C@@H]2N3[C@H]1O[C@]1(CC[C@@]4(O)[C@H]5Cc6ccc(O)c7O[C@@H]1[C@]4(CCN5CC1CC1)c67)[C@@H]3O[C@]21CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45 InChI=1S/C63H72N4O12/c68-37-10-7-34-25-40-61(71)16-13-58(49-55(61,43(34)46(37)74-49)19-22-64(40)28-31-1-2-31)52-67-53(77-58)59(14-17-62(72)41-26-35-8-11-38(69)47-44(35)56(62,50(59)75-47)20-23-65(41)29-32-3-4-32)79-54(67)60(78-52)15-18-63(73)42-27-36-9-12-39(70)48-45(36)57(63,51(60)76-48)21-24-66(42)30-33-5-6-33/h7-12,31-33,40-42,49-54,68-73H,1-6,13-30H2/t40-,41-,42-,49-,50-,51-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61-,62-,63-/m1/s1 RYOONJOVNVZTKA-RFQDSNSESA-N 50347160 CHEMBL1797514 Mu-type opioid receptor Cavia cutleri 22.2 ChEMBL 10.1016/j.bmcl.2011.04.134 10.7270/Q2D79BR5 21641219 Nagase, H; Watanabe, A; Nemoto, T; Nakajima, M; Hasebe, K; Mochizuki, H; Fujii, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347160 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347160&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 56666510 136353846 CHEMBL1797514 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50646863 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)CC[C@]41O[C@@H]2N3[C@H]1O[C@]1(CC[C@@]4(O)[C@H]6Cc7ccc(O)c8O[C@@H]1[C@]4(CCN6CC1CC1)c78)[C@@H]3O[C@]21CC[C@@]2(O)[C@H]3Cc4ccc(O)c6O[C@@H]1[C@]2(CCN3CC1CC1)c46)ccc5O InChI=1S/C60H68N4O12/c1-61-21-18-52-40-31-6-9-34(65)43(40)71-46(52)55(12-15-58(52,68)37(61)24-31)49-64-50(74-55)56(13-16-59(69)38-25-32-7-10-35(66)44-41(32)53(59,47(56)72-44)19-22-62(38)27-29-2-3-29)76-51(64)57(75-49)14-17-60(70)39-26-33-8-11-36(67)45-42(33)54(60,48(57)73-45)20-23-63(39)28-30-4-5-30/h6-11,29-30,37-39,46-51,65-70H,2-5,12-28H2,1H3/t37-,38-,39-,46-,47-,48-,49+,50+,51+,52+,53+,54+,55+,56+,57+,58-,59-,60-/m1/s1 PKBIMJADIDERSN-ZWZIQLJQSA-N 50347161 CHEMBL1797515 Mu-type opioid receptor Cavia cutleri 3.98 ChEMBL 10.1016/j.bmcl.2011.04.134 10.7270/Q2D79BR5 21641219 Nagase, H; Watanabe, A; Nemoto, T; Nakajima, M; Hasebe, K; Mochizuki, H; Fujii, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347161 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347161&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 56676737 136353847 CHEMBL1797515 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50646864 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)CC[C@]41O[C@@H]2N3[C@H]1O[C@]1(CC[C@@]4(O)[C@H]6Cc7ccc(O)c8O[C@@H]1[C@]4(CCN6CC1CC1)c78)[C@@H]3O[C@]21CC[C@@]2(O)[C@H]3Cc4ccc(O)c6O[C@@H]1[C@]2(CCN3C)c46)ccc5O InChI=1S/C57H64N4O12/c1-58-20-17-49-37-28-5-8-31(62)40(37)68-43(49)52(11-14-55(49,65)34(58)23-28)46-61-47(53(71-46)12-15-56(66)35-24-29-6-9-32(63)41-38(29)50(56,44(53)69-41)18-21-59(35)2)73-54(48(61)72-52)13-16-57(67)36-25-30-7-10-33(64)42-39(30)51(57,45(54)70-42)19-22-60(36)26-27-3-4-27/h5-10,27,34-36,43-48,62-67H,3-4,11-26H2,1-2H3/t34-,35-,36-,43-,44-,45-,46+,47+,48+,49+,50+,51+,52+,53+,54+,55-,56-,57-/m1/s1 GSQYWNQTRDEUEA-LJOSRPNMSA-N 50347162 CHEMBL1797516 Mu-type opioid receptor Cavia cutleri 1.85 ChEMBL 10.1016/j.bmcl.2011.04.134 10.7270/Q2D79BR5 21641219 Nagase, H; Watanabe, A; Nemoto, T; Nakajima, M; Hasebe, K; Mochizuki, H; Fujii, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347162 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347162&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 56663038 136353848 CHEMBL1797516 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50646865 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)CC[C@]41O[C@@H]2N3[C@H]1O[C@]1(CC[C@@]4(O)[C@H]6Cc7ccc(O)c8O[C@@H]1[C@]4(CCN6C)c78)[C@@H]3O[C@]21CC[C@@]2(O)[C@H]3Cc4ccc(O)c6O[C@@H]1[C@]2(CCN3C)c46)ccc5O InChI=1S/C54H60N4O12/c1-55-19-16-46-34-25-4-7-28(59)37(34)65-40(46)49(10-13-52(46,62)31(55)22-25)43-58-44(68-49)50(11-14-53(63)32-23-26-5-8-29(60)38-35(26)47(53,41(50)66-38)17-20-56(32)2)70-45(58)51(69-43)12-15-54(64)33-24-27-6-9-30(61)39-36(27)48(54,42(51)67-39)18-21-57(33)3/h4-9,31-33,40-45,59-64H,10-24H2,1-3H3/t31-,32-,33-,40-,41-,42-,43+,44+,45+,46+,47+,48+,49+,50+,51+,52-,53-,54-/m1/s1 BJGJEHKSYZQQRY-RNFGUWEESA-N 50347163 CHEMBL1797517 Mu-type opioid receptor Cavia cutleri 1.05 ChEMBL 10.1016/j.bmcl.2011.04.134 10.7270/Q2D79BR5 21641219 Nagase, H; Watanabe, A; Nemoto, T; Nakajima, M; Hasebe, K; Mochizuki, H; Fujii, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347163 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347163&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 56676738 136353849 CHEMBL1797517 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50646866 Oc1ccc2C[C@@H]3[C@@H]4CC[C@]5(O[C@@H]6N7[C@H]5O[C@]5(CC[C@H]8[C@H]9Cc%10ccc(O)c%11O[C@@H]5[C@]8(CCN9CC5CC5)c%10%11)[C@@H]7O[C@]65CC[C@H]6[C@H]7Cc8ccc(O)c9O[C@@H]5[C@]6(CCN7CC5CC5)c89)[C@@H]5Oc1c2[C@]45CCN3CC1CC1 InChI=1S/C63H72N4O9/c68-43-10-7-34-25-40-37-13-16-61(52-58(37,46(34)49(43)71-52)19-22-64(40)28-31-1-2-31)55-67-56(74-61)62(17-14-38-41-26-35-8-11-44(69)50-47(35)59(38,53(62)72-50)20-23-65(41)29-32-3-4-32)76-57(67)63(75-55)18-15-39-42-27-36-9-12-45(70)51-48(36)60(39,54(63)73-51)21-24-66(42)30-33-5-6-33/h7-12,31-33,37-42,52-57,68-70H,1-6,13-30H2/t37-,38-,39-,40+,41+,42+,52+,53+,54+,55-,56-,57-,58-,59-,60-,61-,62-,63-/m0/s1 AKRUZRBHEYKLPW-PTFQVOMSSA-N 50347164 CHEMBL1797518 Mu-type opioid receptor Cavia cutleri 22.3 ChEMBL 10.1016/j.bmcl.2011.04.134 10.7270/Q2D79BR5 21641219 Nagase, H; Watanabe, A; Nemoto, T; Nakajima, M; Hasebe, K; Mochizuki, H; Fujii, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347164 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347164&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 56683403 136353850 CHEMBL1797518 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50665532 FC(F)(F)c1cc(COC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)CCC(=O)N(C2CCN(CCc3ccccc3)CC2)c2ccccc2)cc(c1)C(F)(F)F InChI=1S/C43H42F6N4O4/c44-42(45,46)32-23-30(24-33(26-32)43(47,48)49)28-57-41(56)38(25-31-27-50-37-14-8-7-13-36(31)37)51-39(54)15-16-40(55)53(34-11-5-2-6-12-34)35-18-21-52(22-19-35)20-17-29-9-3-1-4-10-29/h1-14,23-24,26-27,35,38,50H,15-22,25,28H2,(H,51,54)/t38-/m0/s1 XJMWWALONVOUBI-LHEWISCISA-N 50355374 CHEMBL1835843 Mu-type opioid receptor Cavia cutleri 410 ChEMBL 10.1016/j.bmc.2011.08.027 10.7270/Q2B56K4J 21925887 Vardanyan, R; Kumirov, VK; Nichol, GS; Davis, P; Liktor-Busa, E; Rankin, D; Varga, E; Vanderah, T; Porreca, F; Lai, J; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355374 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355374&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 56665366 136362060 CHEMBL1835843 ZINC95539992 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50665533 FC(F)(F)c1cc(COC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)CCCC(=O)N(C2CCN(CCc3ccccc3)CC2)c2ccccc2)cc(c1)C(F)(F)F InChI=1S/C44H44F6N4O4/c45-43(46,47)33-24-31(25-34(27-33)44(48,49)50)29-58-42(57)39(26-32-28-51-38-15-8-7-14-37(32)38)52-40(55)16-9-17-41(56)54(35-12-5-2-6-13-35)36-19-22-53(23-20-36)21-18-30-10-3-1-4-11-30/h1-8,10-15,24-25,27-28,36,39,51H,9,16-23,26,29H2,(H,52,55)/t39-/m0/s1 FSXQTMXCXNMEIZ-KDXMTYKHSA-N 50355375 CHEMBL1835844 Mu-type opioid receptor Cavia cutleri 55 ChEMBL 10.1016/j.bmc.2011.08.027 10.7270/Q2B56K4J 21925887 Vardanyan, R; Kumirov, VK; Nichol, GS; Davis, P; Liktor-Busa, E; Rankin, D; Varga, E; Vanderah, T; Porreca, F; Lai, J; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355375 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355375&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 56668794 136362061 CHEMBL1835844 ZINC95540077 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50665535 CCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 InChI=1S/C22H28N2O/c1-2-22(25)24(20-11-7-4-8-12-20)21-14-17-23(18-15-21)16-13-19-9-5-3-6-10-19/h3-12,21H,2,13-18H2,1H3 PJMPHNIQZUBGLI-UHFFFAOYSA-N 50008984 4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-phthalazin-1-one::CHEMBL596::Duragesic-100::Duragesic-12::Duragesic-25::Duragesic-50::Duragesic-75::FENTANYL::FENTANYL CITRATE::FENTANYL-HCl::Fentanyl-100::Fentanyl-12::Fentanyl-25::Fentanyl-50::Fentanyl-75::Fentora::Innovar::Ionsys::N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide::N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide(Fentanyl)::N-(1-phenethylpiperidin-4-yl)-N-phenylpropionamide Mu-type opioid receptor Cavia cutleri 1.9 ChEMBL 10.1016/j.bmc.2011.08.027 10.7270/Q2B56K4J 21925887 Vardanyan, R; Kumirov, VK; Nichol, GS; Davis, P; Liktor-Busa, E; Rankin, D; Varga, E; Vanderah, T; Porreca, F; Lai, J; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008984&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 7V7 5TZO,8EF5,7U64 3345 103922051 119915 CHEMBL596 DB00813 1626 ZINC02522669 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50664042 C[C@@H](N1Cc2cc(O)ccc2CC(N)C1=O)C(=O)NC1Cc2ccccc2CN(CC(N)=O)C1=O InChI=1S/C25H29N5O5/c1-14(30-12-18-8-19(31)7-6-16(18)9-20(26)24(30)34)23(33)28-21-10-15-4-2-3-5-17(15)11-29(25(21)35)13-22(27)32/h2-8,14,20-21,31H,9-13,26H2,1H3,(H2,27,32)(H,28,33)/t14-,20?,21?/m1/s1 ACFTTXWQZSBVGL-OZJRSANCSA-N 50354653 CHEMBL1834250 Mu-type opioid receptor Cavia cutleri 3.6 ChEMBL 10.1021/jm2003574 10.7270/Q24Q7VC1 21870874 De Wachter, R; de Graaf, C; Keresztes, A; Vandormael, B; Ballet, S; Toth, G; Rognan, D; Tourwe, D Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354653 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354653&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 56678760 136361339 CHEMBL1834250 ZINC72125935 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50701987 CN(C\C=C(/C)c1ccccc1)Cc1ccccc1 InChI=1S/C18H21N/c1-16(18-11-7-4-8-12-18)13-14-19(2)15-17-9-5-3-6-10-17/h3-13H,14-15H2,1-2H3/b16-13+ WBOWXDJKRSQWJC-DTQAZKPQSA-N 50357428 CHEMBL1917701 Mu-type opioid receptor Cavia cutleri 119 ChEMBL 10.1016/j.bmc.2011.09.016 10.7270/Q2VH5P7V 21967807 Rossi, D; Pedrali, A; Urbano, M; Gaggeri, R; Serra, M; Fernandez, L; Fernandez, M; Caballero, J; Ronsisvalle, S; Prezzavento, O; Schepmann, D; Wuensch, B; Peviani, M; Curti, D; Azzolina, O; Collina, S University of Pavia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50357428 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50357428&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 57400896 136961452 CHEMBL1917701 ZINC73163029 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50701988 COc1ccc(cc1)C(\C)=C\CN(C)Cc1ccccc1 InChI=1S/C19H23NO/c1-16(18-9-11-19(21-3)12-10-18)13-14-20(2)15-17-7-5-4-6-8-17/h4-13H,14-15H2,1-3H3/b16-13+ MWZUCLVNPHWLPA-DTQAZKPQSA-N 50357429 CHEMBL1917702 Mu-type opioid receptor Cavia cutleri 92 ChEMBL 10.1016/j.bmc.2011.09.016 10.7270/Q2VH5P7V 21967807 Rossi, D; Pedrali, A; Urbano, M; Gaggeri, R; Serra, M; Fernandez, L; Fernandez, M; Caballero, J; Ronsisvalle, S; Prezzavento, O; Schepmann, D; Wuensch, B; Peviani, M; Curti, D; Azzolina, O; Collina, S University of Pavia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50357429 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50357429&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 57402667 136961453 CHEMBL1917702 ZINC73163030 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50701989 C\C(=C/CN1CCC(Cc2ccccc2)CC1)c1ccccc1 InChI=1S/C22H27N/c1-19(22-10-6-3-7-11-22)12-15-23-16-13-21(14-17-23)18-20-8-4-2-5-9-20/h2-12,21H,13-18H2,1H3/b19-12+ MOWWHGHVCNLNNH-XDHOZWIPSA-N 50357430 CHEMBL1917711 Mu-type opioid receptor Cavia cutleri 152 ChEMBL 10.1016/j.bmc.2011.09.016 10.7270/Q2VH5P7V 21967807 Rossi, D; Pedrali, A; Urbano, M; Gaggeri, R; Serra, M; Fernandez, L; Fernandez, M; Caballero, J; Ronsisvalle, S; Prezzavento, O; Schepmann, D; Wuensch, B; Peviani, M; Curti, D; Azzolina, O; Collina, S University of Pavia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50357430 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50357430&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 57397470 136961454 CHEMBL1917711 ZINC73157986 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50701990 COc1ccc(cc1)C(\C)=C\CN1CCC(Cc2ccccc2)CC1 InChI=1S/C23H29NO/c1-19(22-8-10-23(25-2)11-9-22)12-15-24-16-13-21(14-17-24)18-20-6-4-3-5-7-20/h3-12,21H,13-18H2,1-2H3/b19-12+ IQJNWBDZKFSMLG-XDHOZWIPSA-N 50357431 CHEMBL1917712 Mu-type opioid receptor Cavia cutleri 149 ChEMBL 10.1016/j.bmc.2011.09.016 10.7270/Q2VH5P7V 21967807 Rossi, D; Pedrali, A; Urbano, M; Gaggeri, R; Serra, M; Fernandez, L; Fernandez, M; Caballero, J; Ronsisvalle, S; Prezzavento, O; Schepmann, D; Wuensch, B; Peviani, M; Curti, D; Azzolina, O; Collina, S University of Pavia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50357431 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50357431&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 57397472 136961455 CHEMBL1917712 ZINC73157990 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50730036 C[C@@H]1CO[C@@]23CCC4(C[C@H]12)C1Cc2ccc(O)c5O[C@@H]3C4(CCN1CC1CC1)c25 InChI=1S/C25H31NO3/c1-14-13-28-25-7-6-23(11-17(14)25)19-10-16-4-5-18(27)21-20(16)24(23,22(25)29-21)8-9-26(19)12-15-2-3-15/h4-5,14-15,17,19,22,27H,2-3,6-13H2,1H3/t14-,17-,19?,22-,23?,24?,25+/m1/s1 LILDUHGQHOLNNN-XTFSPYNFSA-N 50076001 3-cyclopropylmethyl-18-methyl-(15S)-13,16-dioxa-3-azaheptacyclo[13.5.2.12,8.01,6.06,14.07,12.015,19]tricosa-7,9,11-trien-11-ol::CHEMBL349636 Mu-type opioid receptor Cavia cutleri 0.700000 ChEMBL 10.1016/s0960-894x(99)00085-2 10.7270/Q2FT8MJK 10206545 Husbands, SM; Breeden, SW; Grivas, K; Lewis, JW University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076001 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076001&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380370 103969001 CHEMBL349636 ZINC27898883 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50730041 CC1(C)OC23CCC4(CC2C1(C)C)C1Cc2ccc(O)c5OC3C4(CCN1CC1CC1)c25 InChI=1S/C28H37NO3/c1-24(2)19-14-26-9-10-28(19,32-25(24,3)4)23-27(26)11-12-29(15-16-5-6-16)20(26)13-17-7-8-18(30)22(31-23)21(17)27/h7-8,16,19-20,23,30H,5-6,9-15H2,1-4H3 MFRSJMQUIFQWSF-UHFFFAOYSA-N 50076003 3-cyclopropylmethyl-18,18-dimethyl-(15S)-13,16-dioxa-3-azaheptacyclo[13.5.2.12,8.01,6.06,14.07,12.015,19]tricosa-7,9,11-trien-11-ol::CHEMBL353876 Mu-type opioid receptor Cavia cutleri 0.200000 ChEMBL 10.1016/s0960-894x(99)00085-2 10.7270/Q2FT8MJK 10206545 Husbands, SM; Breeden, SW; Grivas, K; Lewis, JW University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076003 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076003&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380352 103969003 CHEMBL353876 ZINC36221884 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50730042 CO[C@@]12CCC3(C[C@@H]1[C@](C)(O)C(C)C)[C@H]1Cc4ccc(O)c5O[C@@H]2C3(CCN1C)c45 InChI=1S/C25H35NO4/c1-14(2)22(3,28)17-13-23-8-9-25(17,29-5)21-24(23)10-11-26(4)18(23)12-15-6-7-16(27)20(30-21)19(15)24/h6-7,14,17-18,21,27-28H,8-13H2,1-5H3/t17-,18-,21-,22-,23?,24?,25+/m1/s1 KUVAOOWSSNDJIR-XAIDZZPMSA-N 50076005 2-[11,15-dimethoxy-3-methyl-(14R,15S)-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-16-yl]-3,3-dimethyl-2-butanol::CHEMBL349841 Mu-type opioid receptor Cavia cutleri 0.100000 ChEMBL 10.1016/s0960-894x(99)00085-2 10.7270/Q2FT8MJK 10206545 Husbands, SM; Breeden, SW; Grivas, K; Lewis, JW University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076005 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076005&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380353 103969005 CHEMBL349841 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50730046 CO[C@@]12CC[C@@]3(C[C@@H]1[C@](C)(O)C(C)(C)C)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45 InChI=1S/C29H41NO4/c1-25(2,3)26(4,32)20-15-27-10-11-29(20,33-5)24-28(27)12-13-30(16-17-6-7-17)21(27)14-18-8-9-19(31)23(34-24)22(18)28/h8-9,17,20-21,24,31-32H,6-7,10-16H2,1-5H3/t20-,21-,24-,26+,27-,28+,29+/m1/s1 RMRJXGBAOAMLHD-CTAPUXPBSA-N 50354578 BUPRENORPHINE::US10752592, Compound buprenorphine::US11534436, Compound buprenorphine::US9315514, Buprenorphine Mu-type opioid receptor Cavia cutleri 1.3 ChEMBL 10.1016/s0960-894x(99)00085-2 10.7270/Q2FT8MJK 10206545 Husbands, SM; Breeden, SW; Grivas, K; Lewis, JW University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354578&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9848990 136361264 C08007 ZINC38321402 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50730049 COc1ccc2C[C@H]3N(C)CCC45[C@@H](Oc1c24)[C@@]1(CCC35C[C@@H]1[C@](C)(O)C(C)C)OC InChI=1S/C26H37NO4/c1-15(2)23(3,28)18-14-24-9-10-26(18,30-6)22-25(24)11-12-27(4)19(24)13-16-7-8-17(29-5)21(31-22)20(16)25/h7-8,15,18-19,22,28H,9-14H2,1-6H3/t18-,19-,22-,23-,24?,25?,26+/m1/s1 DGCJDEPVSXDXCG-FEQPPXRYSA-N 50076007 2-(11,15-dimethoxy-3-methyl-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-16-yl)-3-methyl-2-butanol::CHEMBL355296 Mu-type opioid receptor Cavia cutleri 0.400000 ChEMBL 10.1016/s0960-894x(99)00085-2 10.7270/Q2FT8MJK 10206545 Husbands, SM; Breeden, SW; Grivas, K; Lewis, JW University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076007 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076007&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380063 103969006 CHEMBL355296 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50730062 C[C@H]1CO[C@@]23CCC4(C[C@@H]12)[C@H]1Cc2ccc(O)c5O[C@@H]3C4(CCN1CC1CC1)c25 InChI=1S/C25H31NO3/c1-14-13-28-25-7-6-23(11-17(14)25)19-10-16-4-5-18(27)21-20(16)24(23,22(25)29-21)8-9-26(19)12-15-2-3-15/h4-5,14-15,17,19,22,27H,2-3,6-13H2,1H3/t14-,17-,19+,22+,23?,24?,25-/m0/s1 LILDUHGQHOLNNN-VGURIWQOSA-N 50076011 3-cyclopropylmethyl-18-methyl-(15S)-13,16-dioxa-3-azaheptacyclo[13.5.2.12,8.01,6.06,14.07,12.015,19]tricosa-7,9,11-trien-11-ol::CHEMBL166853 Mu-type opioid receptor Cavia cutleri 0.300000 ChEMBL 10.1016/s0960-894x(99)00085-2 10.7270/Q2FT8MJK 10206545 Husbands, SM; Breeden, SW; Grivas, K; Lewis, JW University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076011&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380064 103969009 CHEMBL166853 ZINC27899661 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50730063 CC1C2CC34CCC2(OC1(C)C)C1Oc2c5c(CC3N(C)CCC415)ccc2O InChI=1S/C24H31NO3/c1-13-15-12-22-7-8-24(15,28-21(13,2)3)20-23(22)9-10-25(4)17(22)11-14-5-6-16(26)19(27-20)18(14)23/h5-6,13,15,17,20,26H,7-12H2,1-4H3 NXPVKARTMAUCTN-UHFFFAOYSA-N 50076010 3,17,17,18-tetramethyl-13,16-dioxa-3-azaheptacyclo[13.5.2.12,8.01,6.06,14.07,12.015,19]tricosa-7,9,11-trien-11-ol::CHEMBL169367 Mu-type opioid receptor Cavia cutleri 0.500000 ChEMBL 10.1016/s0960-894x(99)00085-2 10.7270/Q2FT8MJK 10206545 Husbands, SM; Breeden, SW; Grivas, K; Lewis, JW University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076010&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44380600 103969008 CHEMBL169367 ZINC36221907 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50730065 COC12CCC3(CC1C(C)(C)O)C1Cc4ccc(O)c5OC2C3(CCN1CC1CC1)c45 InChI=1S/C26H35NO4/c1-23(2,29)18-13-24-8-9-26(18,30-3)22-25(24)10-11-27(14-15-4-5-15)19(24)12-16-6-7-17(28)21(31-22)20(16)25/h6-7,15,18-19,22,28-29H,4-5,8-14H2,1-3H3 OIJXLIIMXHRJJH-UHFFFAOYSA-N 50076002 2-(3-cyclopropylmethyl-11-hydroxy-15-methoxy-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11-trien-16-yl)-2-propanol::CHEMBL353979::Diprenorphine Mu-type opioid receptor Cavia cutleri 0.200000 ChEMBL 10.1016/s0960-894x(99)00085-2 10.7270/Q2FT8MJK 10206545 Husbands, SM; Breeden, SW; Grivas, K; Lewis, JW University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076002 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076002&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 4491165 103969002 CHEMBL353979 ZINC05440171 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50743772 CSCC[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)C1CC2(C)C(C)C(Cc3ccc(O)cc23)N1C)C(N)=O InChI=1S/C34H46N6O6S/c1-20-27-15-22-10-11-23(41)16-24(22)34(20,2)17-28(40(27)3)33(46)37-18-29(42)36-19-30(43)38-26(14-21-8-6-5-7-9-21)32(45)39-25(31(35)44)12-13-47-4/h5-11,16,20,25-28,41H,12-15,17-19H2,1-4H3,(H2,35,44)(H,36,42)(H,37,46)(H,38,43)(H,39,45)/t20?,25-,26+,27?,28?,34?/m1/s1 XDEWTAYBHFQFTJ-LTIKIPGZSA-N 50028652 (+)-8-Hydroxy-3,6,11-trimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-4-carboxylic acid [({[1-(1-carbamoyl-3-methylsulfanyl-propylcarbamoyl)-2-phenyl-ethylcarbamoyl]-methyl}-carbamoyl)-methyl]-amide::(-)-8-Hydroxy-3,6,11-trimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-4-carboxylic acid [({[1-(1-carbamoyl-3-methylsulfanyl-propylcarbamoyl)-2-phenyl-ethylcarbamoyl]-methyl}-carbamoyl)-methyl]-amide::CHEMBL2372185 Mu-type opioid receptor Cavia cutleri 7970 ChEMBL 10.1021/jm00354a006 10.7270/Q2NG4R56 7154002 Ramakrishnan, K; Portoghese, PS TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028652 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028652&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73348664 103937856 CHEMBL2372185 ZINC49694998 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50743774 CC1C2Cc3ccc(O)cc3C1(C)CC(N2C)C(N)=O InChI=1S/C16H22N2O2/c1-9-13-6-10-4-5-11(19)7-12(10)16(9,2)8-14(15(17)20)18(13)3/h4-5,7,9,13-14,19H,6,8H2,1-3H3,(H2,17,20) MCAPGXLLTIUQQF-UHFFFAOYSA-N 50028654 (+)-8-Hydroxy-3,6,11-trimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-4-carboxylic acid amide::(-)-8-Hydroxy-3,6,11-trimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-4-carboxylic acid amide::CHEMBL284060 Mu-type opioid receptor Cavia cutleri 6090 ChEMBL 10.1021/jm00354a006 10.7270/Q2NG4R56 7154002 Ramakrishnan, K; Portoghese, PS TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028654 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028654&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44280774 103937858 CHEMBL284060 ZINC38148504 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50743775 CC1C2(C)CCN(C)C1(Cc1ccc(O)cc21)C(N)=O InChI=1S/C16H22N2O2/c1-10-15(2)6-7-18(3)16(10,14(17)20)9-11-4-5-12(19)8-13(11)15/h4-5,8,10,19H,6-7,9H2,1-3H3,(H2,17,20) RKEAFTOSUVAQES-UHFFFAOYSA-N 50028655 8-Hydroxy-3,6,11-trimethyl-3,4,5,6-tetrahydro-1H-2,6-methano-benzo[d]azocine-2-carboxylic acid amide::CHEMBL285083 Mu-type opioid receptor Cavia cutleri 2820 ChEMBL 10.1021/jm00354a006 10.7270/Q2NG4R56 7154002 Ramakrishnan, K; Portoghese, PS TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028655 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028655&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44280765 103937859 CHEMBL285083 ZINC38148508 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50743777 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 57 ChEMBL 10.1021/jm00354a006 10.7270/Q2NG4R56 7154002 Ramakrishnan, K; Portoghese, PS TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50743779 C[C@H]1[C@@H]2Cc3ccc(O)cc3[C@]1(C)CCN2C InChI=1S/C15H21NO/c1-10-14-8-11-4-5-12(17)9-13(11)15(10,2)6-7-16(14)3/h4-5,9-10,14,17H,6-8H2,1-3H3/t10-,14-,15+/m0/s1 YGSVZRIZCHZUHB-NZVBXONLSA-N 50367062 METAZOCINE Mu-type opioid receptor Cavia cutleri 94 ChEMBL 10.1021/jm00354a006 10.7270/Q2NG4R56 7154002 Ramakrishnan, K; Portoghese, PS TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367062 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367062&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3037886 160846164 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50647979 Cn1c2CCCCc2c2C[C@@]3(O)[C@H]4Cc5ccc(O)c6O[C@@H](c12)[C@]3(CCN4CC1CC1)c56 InChI=1S/C27H32N2O3/c1-28-19-5-3-2-4-17(19)18-13-27(31)21-12-16-8-9-20(30)24-22(16)26(27,25(32-24)23(18)28)10-11-29(21)14-15-6-7-15/h8-9,15,21,25,30-31H,2-7,10-14H2,1H3/t21-,25+,26+,27-/m1/s1 FFTBXBGJNXJGQT-NVSKSXHLSA-N 50229231 CHEMBL610534 Mu-type opioid receptor Cavia cutleri 16.8 ChEMBL 10.1021/jm00109a027 10.7270/Q2T43TPG 1851846 Portoghese, PS; Nagase, H; MaloneyHuss, KE; Lin, CE; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50229231 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50229231&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46877642 381615752 CHEMBL610534 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50647980 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=CC[C@@]35O)c1ccccc1 InChI=1S/C26H27NO3/c28-20-9-8-18-14-21-26(29)11-10-19(17-4-2-1-3-5-17)24-25(26,22(18)23(20)30-24)12-13-27(21)15-16-6-7-16/h1-5,8-10,16,21,24,28-29H,6-7,11-15H2/t21-,24+,25+,26-/m1/s1 KUOJGXGKZKOYKG-CBRSEMLDSA-N 50229232 CHEMBL610527 Mu-type opioid receptor Cavia cutleri 0.005 ChEMBL 10.1021/jm00109a027 10.7270/Q2T43TPG 1851846 Portoghese, PS; Nagase, H; MaloneyHuss, KE; Lin, CE; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50229232 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50229232&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46877620 381615753 CHEMBL610527 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50647981 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1 DQCKKXVULJGBQN-XFWGSAIBSA-N 60212 (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::MLS000069607::NALTREXONE HYDROCHLORIDE::SMR000058767::US10988481, Compound NTX::US9107954, naltrexone::cid_5485201 Mu-type opioid receptor Cavia cutleri 0.760 ChEMBL 10.1021/jm00109a027 10.7270/Q2T43TPG 1851846 Portoghese, PS; Nagase, H; MaloneyHuss, KE; Lin, CE; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60212&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5360515 252639834 DB00704 C07253 ZINC00001773 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50647982 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1oc2ccccc2c1C[C@@]35O InChI=1S/C26H25NO4/c28-18-8-7-15-11-20-26(29)12-17-16-3-1-2-4-19(16)30-22(17)24-25(26,21(15)23(18)31-24)9-10-27(20)13-14-5-6-14/h1-4,7-8,14,20,24,28-29H,5-6,9-13H2/t20-,24+,25+,26-/m1/s1 ZHVWWEYETMPAMX-IFKAHUTRSA-N 82552 CAS_111555-58-9::NTB::naltrindolebenzofuran Mu-type opioid receptor Cavia cutleri 18.8 ChEMBL 10.1021/jm00109a027 10.7270/Q2T43TPG 1851846 Portoghese, PS; Nagase, H; MaloneyHuss, KE; Lin, CE; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82552 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82552&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search ZY8 8SI5,8SI6 5486827 136350522 ZINC03874478 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50647984 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2ccccc2c1C[C@@]35O InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24+,25+,26-/m1/s1 WIYUZYBFCWCCQJ-IFKAHUTRSA-N 50370067 CHEMBL1237164 Mu-type opioid receptor Cavia cutleri 3.8 ChEMBL 10.1021/jm00109a027 10.7270/Q2T43TPG 1851846 Portoghese, PS; Nagase, H; MaloneyHuss, KE; Lin, CE; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50370067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50370067&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search EJ4 4N6H,4EJ4 5497186 160849169 CHEMBL1237164 C18128 ZINC03802871 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50647993 Cn1c2[C@@H]3Oc4c5c(C[C@H]6N(CC7CC7)CC[C@@]35[C@@]6(O)Cc2c2ccccc12)ccc4O InChI=1S/C27H28N2O3/c1-28-19-5-3-2-4-17(19)18-13-27(31)21-12-16-8-9-20(30)24-22(16)26(27,25(32-24)23(18)28)10-11-29(21)14-15-6-7-15/h2-5,8-9,15,21,25,30-31H,6-7,10-14H2,1H3/t21-,25+,26+,27-/m1/s1 CRTCCMARDBQOKA-NVSKSXHLSA-N 50451343 CHEMBL477154 Mu-type opioid receptor Cavia cutleri 13.7 ChEMBL 10.1021/jm00109a027 10.7270/Q2T43TPG 1851846 Portoghese, PS; Nagase, H; MaloneyHuss, KE; Lin, CE; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50451343 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50451343&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5362396 225145344 CHEMBL477154 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50647995 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1nc2ccccc2nc1C[C@@]35O InChI=1S/C26H25N3O3/c30-19-8-7-15-11-20-26(31)12-18-22(28-17-4-2-1-3-16(17)27-18)24-25(26,21(15)23(19)32-24)9-10-29(20)13-14-5-6-14/h1-4,7-8,14,20,24,30-31H,5-6,9-13H2/t20-,24+,25+,26-/m1/s1 KASNFNADFKDSTB-IFKAHUTRSA-N 50229230 CHEMBL610007 Mu-type opioid receptor Cavia cutleri 7.3 ChEMBL 10.1021/jm00109a027 10.7270/Q2T43TPG 1851846 Portoghese, PS; Nagase, H; MaloneyHuss, KE; Lin, CE; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50229230 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50229230&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14423337 381615751 CHEMBL610007 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50747634 CC[C@@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)OC InChI=1S/C47H74N14O10/c1-6-28(4)39(45(70)71-5)61-42(67)34(15-11-21-54-47(51)52)58-41(66)33(14-10-20-53-46(49)50)59-43(68)35(22-27(2)3)60-44(69)36(24-29-12-8-7-9-13-29)57-38(64)26-55-37(63)25-56-40(65)32(48)23-30-16-18-31(62)19-17-30/h7-9,12-13,16-19,27-28,32-36,39,62H,6,10-11,14-15,20-26,48H2,1-5H3,(H,55,63)(H,56,65)(H,57,64)(H,58,66)(H,59,68)(H,60,69)(H,61,67)(H4,49,50,53)(H4,51,52,54)/t28-,32+,33+,34+,35+,36+,39+/m1/s1 SVSJNSUODBXQIG-RCNKGVCCSA-N 50367335 CHEMBL1791447 Mu-type opioid receptor Cavia cutleri 340 ChEMBL 10.1021/jm00157a018 10.7270/Q2M04606 2879914 Lipkowski, AW; Tam, SW; Portoghese, PS TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367335 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367335&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 56674946 160846437 CHEMBL1791447 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50747638 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)CCC4=O)ccc5O InChI=1S/C17H19NO4/c1-18-7-6-16-13-9-2-3-10(19)14(13)22-15(16)11(20)4-5-17(16,21)12(18)8-9/h2-3,12,15,19,21H,4-8H2,1H3/t12-,15+,16+,17-/m1/s1 UQCNKQCJZOAFTQ-ISWURRPUSA-N 50001707 10,17-dihydroxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::10,17-dihydroxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(oxymorphone)::10,17-dihydroxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(xymorphone)::10,17-dihydroxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-trien-14-one::CHEMBL963::Codoxy::Combunox::Numorphan::OXYMORPHONE::Opana::Oxycet::PERCODAN-DEMI::Percocet::Percodan::Roxicet::Roxilox::Roxiprin::Tylox::Tylox-325 Mu-type opioid receptor Cavia cutleri 15 ChEMBL 10.1021/jm00157a018 10.7270/Q2M04606 2879914 Lipkowski, AW; Tam, SW; Portoghese, PS TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001707 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001707&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5284604 103916122 CHEMBL963 DB01192 7094 C08019 ZINC03875483 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50747642 NC(=O)NN=C1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1C2(CCN3CC1CC1)c45 InChI=1S/C21H26N4O4/c22-19(27)24-23-13-5-6-21(28)15-9-12-3-4-14(26)17-16(12)20(21,18(13)29-17)7-8-25(15)10-11-1-2-11/h3-4,11,15,18,26,28H,1-2,5-10H2,(H3,22,24,27)/t15?,18-,20?,21+/m0/s1 UBLSCNUJVVIEQF-DOFKUTCQSA-N 50019647 CHEMBL19982::Naltrexone semicarbazone Mu-type opioid receptor Cavia cutleri 0.480000 ChEMBL 10.1021/jm00157a018 10.7270/Q2M04606 2879914 Lipkowski, AW; Tam, SW; Portoghese, PS TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019647 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019647&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44273477 103930570 CHEMBL19982 ZINC28229791 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50747645 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C28H37N5O7/c1-17(2)12-23(28(39)40)33-27(38)22(14-18-6-4-3-5-7-18)32-25(36)16-30-24(35)15-31-26(37)21(29)13-19-8-10-20(34)11-9-19/h3-11,17,21-23,34H,12-16,29H2,1-2H3,(H,30,35)(H,31,37)(H,32,36)(H,33,38)(H,39,40)/t21-,22-,23-/m0/s1 URLZCHNOLZSCCA-VABKMULXSA-N 50001465 (S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::([Leu]-enkephalin)2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::(enkephalin)2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-1-oxo-3-phenyl-propylamino]-4-methyl-pentanoic acid::2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::2-[1-[1-amino-2-(4-hydroxyphenyl)-(1S)-ethylcarboxamidomethylcarboxamidomethylcarboxamido]-2-phenyl-(1S)-ethylcarboxamido]-4-methyl-(2S)-pentanoic acid::2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid(Enkephalin)::2-{1-[1-amino-2-(4-hydroxyphenyl)ethylcarboxamidomethylcarboxamidomethylcarboxamido]-2-phenylethylcarboxamido}-4-methylpentanoic acid::CHEMBL8234::ENKEPHALIN::Leu-ENKEPHALIN::Leu5-Enkephalin::Tyr-Gly-Gly-Phe-Leu-OH Mu-type opioid receptor Cavia cutleri 380 ChEMBL 10.1021/jm00157a018 10.7270/Q2M04606 2879914 Lipkowski, AW; Tam, SW; Portoghese, PS TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001465&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 461776 103915930 CHEMBL8234 ZINC14952116 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50747647 Cl.CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)N\N=C1\CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3C)c45)C(=O)OC InChI=1S/C52H78N14O10/c1-7-29(4)40(47(72)75-6)63-44(69)34(16-12-23-58-49(55)56)59-43(68)33(15-11-22-57-48(53)54)60-45(70)35(25-28(2)3)61-46(71)36(26-30-13-9-8-10-14-30)62-50(73)65-64-32-19-20-52(74)38-27-31-17-18-37(67)41-39(31)51(52,42(32)76-41)21-24-66(38)5/h8-10,13-14,17-18,28-29,33-36,38,40,42,67,74H,7,11-12,15-16,19-27H2,1-6H3,(H,59,68)(H,60,70)(H,61,71)(H,63,69)(H4,53,54,57)(H4,55,56,58)(H2,62,65,73)/t29?,33?,34?,35?,36?,38?,40?,42-,51?,52+/m0/s1 SKDBBPPYNGKLQQ-ZKOYHRFVSA-N 50367340 CHEMBL1202428::CHEMBL3144355 Mu-type opioid receptor Cavia cutleri 16 ChEMBL 10.1021/jm00157a018 10.7270/Q2M04606 2879914 Lipkowski, AW; Tam, SW; Portoghese, PS TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367340 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367340&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 90663908 160846442 CHEMBL3144355CHEMBL1202428 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50747655 CC(C)CC(NC(=O)C(Cc1ccccc1)NC(=O)NN=C1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1C2(CCN3C)c45)C(O)=O InChI=1S/C33H41N5O7/c1-18(2)15-23(30(41)42)34-29(40)22(16-19-7-5-4-6-8-19)35-31(43)37-36-21-11-12-33(44)25-17-20-9-10-24(39)27-26(20)32(33,28(21)45-27)13-14-38(25)3/h4-10,18,22-23,25,28,39,44H,11-17H2,1-3H3,(H,34,40)(H,41,42)(H2,35,37,43)/t22?,23?,25?,28-,32?,33+/m0/s1 STLLJPOVGTYRCR-WGKGROJNSA-N 50367337 CHEMBL1202430 Mu-type opioid receptor Cavia cutleri 15 ChEMBL 10.1021/jm00157a018 10.7270/Q2M04606 2879914 Lipkowski, AW; Tam, SW; Portoghese, PS TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367337 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367337&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44273569 160846439 CHEMBL1202430 ZINC28233622 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50747657 CN1CCC23[C@H]4Oc5c2c(CC1[C@]3(O)CCC4=NNC(N)=O)ccc5O InChI=1S/C18H22N4O4/c1-22-7-6-17-13-9-2-3-11(23)14(13)26-15(17)10(20-21-16(19)24)4-5-18(17,25)12(22)8-9/h2-3,12,15,23,25H,4-8H2,1H3,(H3,19,21,24)/t12?,15-,17?,18+/m0/s1 QEDIUYOQWLETJX-UGWGVMABSA-N 50367338 CHEMBL1202432 Mu-type opioid receptor Cavia cutleri 15 ChEMBL 10.1021/jm00157a018 10.7270/Q2M04606 2879914 Lipkowski, AW; Tam, SW; Portoghese, PS TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367338&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44273658 160846440 CHEMBL1202432 ZINC36221729 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50747660 Cl.CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)N\N=C1\CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45)C(=O)OC InChI=1S/C55H82N14O10/c1-6-31(4)43(50(75)78-5)66-47(72)37(15-11-24-61-52(58)59)62-46(71)36(14-10-23-60-51(56)57)63-48(73)38(26-30(2)3)64-49(74)39(27-32-12-8-7-9-13-32)65-53(76)68-67-35-20-21-55(77)41-28-34-18-19-40(70)44-42(34)54(55,45(35)79-44)22-25-69(41)29-33-16-17-33/h7-9,12-13,18-19,30-31,33,36-39,41,43,45,70,77H,6,10-11,14-17,20-29H2,1-5H3,(H,62,71)(H,63,73)(H,64,74)(H,66,72)(H4,56,57,60)(H4,58,59,61)(H2,65,68,76)/t31?,36?,37?,38?,39?,41?,43?,45-,54?,55+/m0/s1 LFTNSDODCONFQS-BPDZOYJKSA-N 50367336 CHEMBL1202429::CHEMBL3144356 Mu-type opioid receptor Cavia cutleri 2.3 ChEMBL 10.1021/jm00157a018 10.7270/Q2M04606 2879914 Lipkowski, AW; Tam, SW; Portoghese, PS TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367336 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367336&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 90663910 160846438 CHEMBL3144356CHEMBL1202429 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50747661 CC(C)CC(NC(=O)C(Cc1ccccc1)NC(=O)NN=C1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1C2(CCN3CC1CC1)c45)C(O)=O InChI=1S/C36H45N5O7/c1-20(2)16-26(33(44)45)37-32(43)25(17-21-6-4-3-5-7-21)38-34(46)40-39-24-12-13-36(47)28-18-23-10-11-27(42)30-29(23)35(36,31(24)48-30)14-15-41(28)19-22-8-9-22/h3-7,10-11,20,22,25-26,28,31,42,47H,8-9,12-19H2,1-2H3,(H,37,43)(H,44,45)(H2,38,40,46)/t25?,26?,28?,31-,35?,36+/m0/s1 BUAROIYDKPQCED-HRUBPFNHSA-N 50367339 CHEMBL1202433 Mu-type opioid receptor Cavia cutleri 0.760000 ChEMBL 10.1021/jm00157a018 10.7270/Q2M04606 2879914 Lipkowski, AW; Tam, SW; Portoghese, PS TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367339 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367339&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44273683 160846441 CHEMBL1202433 ZINC28234006 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50743383 CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H]([C@@H](C)O)C(O)=O InChI=1S/C32H44N6O9S/c1-18(35-29(43)23(33)15-21-9-11-22(40)12-10-21)28(42)34-17-26(41)36-25(16-20-7-5-4-6-8-20)31(45)37-24(13-14-48-3)30(44)38-27(19(2)39)32(46)47/h4-12,18-19,23-25,27,39-40H,13-17,33H2,1-3H3,(H,34,42)(H,35,43)(H,36,41)(H,37,45)(H,38,44)(H,46,47)/t18-,19+,23-,24-,25-,27-/m0/s1 BZCLLEJJCVIHKZ-DHAFWGQXSA-N 50027405 2-{1-[1-{1-[1-amino-2-(4-hydroxyphenyl)ethylcarboxamido]ethylcarboxamidomethylcarboxamido}-2-phenyl-(1S)-ethylcarboxamido]-3-methylsulfanylpropylcarboxamido}-3-hydroxy-(3R)-butanoic acid::CHEMBL14036 Mu-type opioid receptor Cavia cutleri 240 ChEMBL 10.1021/jm00142a002 10.7270/Q2QC0411 6276540 Gacel, G; Fournie-Zaluski, MC; Fellion, E; Roques, BP TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027405 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027405&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269208 103936877 CHEMBL14036 ZINC49853564 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50743384 CC(C)CC(C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C20H32N4O4/c1-12(2)9-13(3)23-18(26)11-22-19(27)14(4)24-20(28)17(21)10-15-5-7-16(25)8-6-15/h5-8,12-14,17,25H,9-11,21H2,1-4H3,(H,22,27)(H,23,26)(H,24,28)/t13?,14-,17-/m0/s1 PUZQCAIXBLYSBU-HUUYTVAOSA-N 50027406 1N-[1-(1,3-dimethylbutylcarbamoylmethylcarbamoyl)-(1S)-ethyl]-2-amino-3-(4-hydroxyphenyl)-(2S)-propanamide::2-Amino-N-(1-{[(1,3-dimethyl-butylcarbamoyl)-methyl]-carbamoyl}-ethyl)-3-(4-hydroxy-phenyl)-propionamide::CHEMBL14094 Mu-type opioid receptor Cavia cutleri 182 ChEMBL 10.1021/jm00142a002 10.7270/Q2QC0411 6276540 Gacel, G; Fournie-Zaluski, MC; Fellion, E; Roques, BP TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027406 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027406&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269167 103936878 CHEMBL14094 ZINC36286722 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50743385 CSCC[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(N)=O InChI=1S/C30H40N6O6S/c1-43-15-13-23(35-28(40)22(31)16-20-9-11-21(37)12-10-20)29(41)33-18-26(38)34-24(17-19-6-3-2-4-7-19)30(42)36-14-5-8-25(36)27(32)39/h2-4,6-7,9-12,22-25,37H,5,8,13-18,31H2,1H3,(H2,32,39)(H,33,41)(H,34,38)(H,35,40)/t22-,23-,24-,25-/m0/s1 UIRWGVLTPPSGEN-QORCZRPOSA-N 50027407 1N-[1-benzyl-2-[5-carbamoyl-(5S)-dihydro-1H-1-pyrrolyl]-2-oxo-(1S)-ethylcarbamoylmethyl]-2-[1-amino-2-(4-hydroxyphenyl)-(1S)-ethylcarboxamido]-4-methylsulfanyl-(2S)-butanamide::CHEMBL13894 Mu-type opioid receptor Cavia cutleri 22 ChEMBL 10.1021/jm00142a002 10.7270/Q2QC0411 6276540 Gacel, G; Fournie-Zaluski, MC; Fellion, E; Roques, BP TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027407 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027407&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 13174933 103936879 CHEMBL13894 ZINC36286713 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50743390 C[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C)[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCS(C)=O)C(O)=O InChI=1S/C29H39N5O8S/c1-18(32-27(38)22(30)15-20-9-11-21(35)12-10-20)26(37)31-17-25(36)34(2)24(16-19-7-5-4-6-8-19)28(39)33-23(29(40)41)13-14-43(3)42/h4-12,18,22-24,35H,13-17,30H2,1-3H3,(H,31,37)(H,32,38)(H,33,39)(H,40,41)/t18-,22-,23-,24-,43?/m0/s1 BDERJSTZOMHTMH-JVYPIJEBSA-N 50027408 2-[1-[1-[1-amino-2-(4-hydroxyphenyl)-(1S)-ethylcarboxamido]-(1S)-ethylcarboxamidomethyl(methyl)carboxamido]-2-phenyl-(1S)-ethylcarboxamido]-4-methylsulfinyl-(2S)-butanoic acid::CHEMBL274204 Mu-type opioid receptor Cavia cutleri 7.2 ChEMBL 10.1021/jm00142a002 10.7270/Q2QC0411 6276540 Gacel, G; Fournie-Zaluski, MC; Fellion, E; Roques, BP TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027408 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027408&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269159 103936880 CHEMBL274204 ZINC36286708 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50743391 CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C27H35N5O7S/c1-40-12-11-21(27(38)39)32-26(37)22(14-17-5-3-2-4-6-17)31-24(35)16-29-23(34)15-30-25(36)20(28)13-18-7-9-19(33)10-8-18/h2-10,20-22,33H,11-16,28H2,1H3,(H,29,34)(H,30,36)(H,31,35)(H,32,37)(H,38,39)/t20-,21-,22-/m0/s1 YFGBQHOOROIVKG-FKBYEOEOSA-N 50019056 (S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methylsulfanyl-butyric acid::([Met]-enkephalin)2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methylsulfanyl-butyric acid([Met]-enkephalin::2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-1-oxo-3-phenyl-propylamino]-4-methylsulfanyl-butyric acid::2-[1-[1-amino-2-(4-hydroxyphenyl)-(1S)-ethylcarboxamidomethylcarboxamidomethylcarboxamido]-2-phenyl-(1S)-ethylcarboxamido]-4-methylsulfanyl-(2S)-butanoic acid::2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methylsulfanyl-butyric acid::CHEMBL13786::H-Tyr-Gly-Gly-Phe-Met-OH::Met5-Enkephalin::[Met5]-enkephalin::met-enkephalin Mu-type opioid receptor Cavia cutleri 200 ChEMBL 10.1021/jm00142a002 10.7270/Q2QC0411 6276540 Gacel, G; Fournie-Zaluski, MC; Fellion, E; Roques, BP TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019056 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019056&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 443363 103930098 CHEMBL13786 1614 C11684 ZINC53147203 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50743395 CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H]([C@@H](C)O)C(O)=O InChI=1S/C31H42N6O9S/c1-18(38)27(31(45)46)37-29(43)23(12-13-47-2)36-30(44)24(15-19-6-4-3-5-7-19)35-26(41)17-33-25(40)16-34-28(42)22(32)14-20-8-10-21(39)11-9-20/h3-11,18,22-24,27,38-39H,12-17,32H2,1-2H3,(H,33,40)(H,34,42)(H,35,41)(H,36,44)(H,37,43)(H,45,46)/t18-,22+,23+,24+,27+/m1/s1 YXVXEONTDCBORX-PEZVSODSSA-N 50027410 2-(1-{1-[1-amino-2-(4-hydroxyphenyl)ethylcarboxamidomethylcarboxamidomethylcarboxamido]-2-phenylethylcarboxamido}-3-methylsulfanylpropylcarboxamido)-3-hydroxy-(3R)-butanoic acid::CHEMBL14204 Mu-type opioid receptor Cavia cutleri 380 ChEMBL 10.1021/jm00142a002 10.7270/Q2QC0411 6276540 Gacel, G; Fournie-Zaluski, MC; Fellion, E; Roques, BP TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027410 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027410&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11787240 103936882 CHEMBL14204 ZINC49853561 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50743396 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 70 ChEMBL 10.1021/jm00142a002 10.7270/Q2QC0411 6276540 Gacel, G; Fournie-Zaluski, MC; Fellion, E; Roques, BP TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50743398 CSCC[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)NC(C)CC(C)C InChI=1S/C22H36N4O4S/c1-14(2)11-15(3)25-20(28)13-24-22(30)19(9-10-31-4)26-21(29)18(23)12-16-5-7-17(27)8-6-16/h5-8,14-15,18-19,27H,9-13,23H2,1-4H3,(H,24,30)(H,25,28)(H,26,29)/t15?,18-,19-/m0/s1 VSKFBIBWZDLGMN-IROOXBOJSA-N 50027409 1N-(1,3-dimethylbutylcarbamoylmethyl)-2-[1-amino-2-(4-hydroxyphenyl)-(1S)-ethylcarboxamido]-4-methylsulfanyl-(2S)-butanamide::CHEMBL280274 Mu-type opioid receptor Cavia cutleri 100 ChEMBL 10.1021/jm00142a002 10.7270/Q2QC0411 6276540 Gacel, G; Fournie-Zaluski, MC; Fellion, E; Roques, BP TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027409 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027409&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269209 103936881 CHEMBL280274 ZINC36286731 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50743400 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H]([C@@H](C)O)C(O)=O InChI=1S/C33H46N6O10/c1-18(2)13-24(32(47)39-28(19(3)41)33(48)49)37-31(46)25(15-20-7-5-4-6-8-20)36-27(43)16-35-30(45)26(17-40)38-29(44)23(34)14-21-9-11-22(42)12-10-21/h4-12,18-19,23-26,28,40-42H,13-17,34H2,1-3H3,(H,35,45)(H,36,43)(H,37,46)(H,38,44)(H,39,47)(H,48,49)/t19-,23+,24+,25+,26+,28+/m1/s1 PKSODCLCMBUCPW-KXJTVXFKSA-N 50019048 (2S,3R)-2-{(S)-2-[(S)-2-(2-{(S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-3-hydroxy-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-3-hydroxy-butyric acid::2-[1-(1-{1-[1-amino-2-(4-hydroxyphenyl)ethylcarboxamido]-2-hydroxyethylcarboxamidomethylcarboxamido}-2-phenylethylcarboxamido)-3-methylbutylcarboxamido]-3-hydroxy-(3R)-butanoic acid::2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-3-hydroxy-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-3-hydroxy-butyric acid::2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-3-hydroxy-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-3-hydroxy-butyric acid(Tyr-D-Ser-Gly-Phe-Leu-Thr)::CHEMBL14230 Mu-type opioid receptor Cavia cutleri 360 ChEMBL 10.1021/jm00142a002 10.7270/Q2QC0411 6276540 Gacel, G; Fournie-Zaluski, MC; Fellion, E; Roques, BP TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019048&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269168 103930090 CHEMBL14230 ZINC49853562 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50776095 COc1ccc2[nH]c3CC4CC(CCN4C)(c3c2c1)c1cccc(O)c1 InChI=1S/C22H24N2O2/c1-24-9-8-22(14-4-3-5-16(25)10-14)13-15(24)11-20-21(22)18-12-17(26-2)6-7-19(18)23-20/h3-7,10,12,15,23,25H,8-9,11,13H2,1-2H3 QRSAMOUGQMIXEX-UHFFFAOYSA-N 50050509 (-)3(1,2,3,4,5,11-Hexahydro-3-methyl-2,6-methano-8-methoxy-6H-aocino[4,5-b]indol-6-yl)phenol methanesulfonate::3(1,2,3,4,5,11-Hexahydro-3-methyl-2,6-methano-8-methoxy-6H-aocino[4,5-b]indol-6-yl)phenol methanesulfonate::CHEMBL65348 Mu-type opioid receptor Cavia cutleri 6760 ChEMBL 10.1021/jm950695s 10.7270/Q2FQ9X82 8642567 Bertha, CM; Ellis, M; Flippen-Anderson, JL; Porreca, F; Rothman, RB; Davis, P; Xu, H; Becketts, K; Rice, KC National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050509&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10689084 103947670 CHEMBL65348 ZINC13756000 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50776102 COc1ccc2c3c(CC4CC3(CCN4C)c3cccc(O)c3)[nH]c2c1 InChI=1S/C22H24N2O2/c1-24-9-8-22(14-4-3-5-16(25)10-14)13-15(24)11-20-21(22)18-7-6-17(26-2)12-19(18)23-20/h3-7,10,12,15,23,25H,8-9,11,13H2,1-2H3 OLISSJIVMPYVMP-UHFFFAOYSA-N 50050506 (-) 3(1,2,3,4,5,11-Hexahydro-3-methyl-2,6-methano-9-methoxy-6H-azocino[4,5-b]indol-6-yl)phenol methanesulfonate::3(1,2,3,4,5,11-Hexahydro-3-methyl-2,6-methano-9-methoxy-6H-azocino[4,5-b]indol-6-yl)phenol methanesulfonate::CHEMBL440123 Mu-type opioid receptor Cavia cutleri 862 ChEMBL 10.1021/jm950695s 10.7270/Q2FQ9X82 8642567 Bertha, CM; Ellis, M; Flippen-Anderson, JL; Porreca, F; Rothman, RB; Davis, P; Xu, H; Becketts, K; Rice, KC National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050506 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050506&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10783942 103947667 CHEMBL440123 ZINC13755996 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50776103 COc1cccc2c3c(CC4CC3(CCN4C)c3cccc(O)c3)[nH]c12 InChI=1S/C22H24N2O2/c1-24-10-9-22(14-5-3-6-16(25)11-14)13-15(24)12-18-20(22)17-7-4-8-19(26-2)21(17)23-18/h3-8,11,15,23,25H,9-10,12-13H2,1-2H3 ZIOKSJYZYLYKRX-UHFFFAOYSA-N 50050507 (-) (2S,6R)-3(1,2,3,4,5,11-Hexahydro-3-methyl-2,6-methano-10-methoxy-6H-azocino[4,5-b]indol-6-yl)phenol methanesulfonate::3(1,2,3,4,5,11-Hexahydro-3-methyl-2,6-methano-10-methoxy-6H-azocino[4,5-b]indol-6-yl)phenol methanesulfonate::CHEMBL302454 Mu-type opioid receptor Cavia cutleri 2890 ChEMBL 10.1021/jm950695s 10.7270/Q2FQ9X82 8642567 Bertha, CM; Ellis, M; Flippen-Anderson, JL; Porreca, F; Rothman, RB; Davis, P; Xu, H; Becketts, K; Rice, KC National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050507 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050507&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10593864 103947668 CHEMBL302454 ZINC13755993 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50768757 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(O)=O InChI=1S/C38H53N7O11/c1-20(2)31(37(55)40-19-30(49)50)45-38(56)32(21(3)4)44-35(53)27(15-16-29(47)48)42-36(54)28(18-23-9-7-6-8-10-23)43-33(51)22(5)41-34(52)26(39)17-24-11-13-25(46)14-12-24/h6-14,20-22,26-28,31-32,46H,15-19,39H2,1-5H3,(H,40,55)(H,41,52)(H,42,54)(H,43,51)(H,44,53)(H,45,56)(H,47,48)(H,49,50)/t22-,26+,27+,28+,31+,32+/m1/s1 FWGXLJYMZWCJJV-RCEFDBTISA-N 50009146 (S)-4-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-4-{(S)-1-[(S)-1-(carboxymethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propylcarbamoyl}-butyric acid::4-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-4-{1-[1-(carboxymethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propylcarbamoyl}-butyric acid::CHEMBL26575 Mu-type opioid receptor Cavia cutleri 15000 ChEMBL 10.1021/jm00040a002 10.7270/Q2ZG6SWK 8035418 Calderon, SN; Rothman, RB; Porreca, F; Flippen-Anderson, JL; McNutt, RW; Xu, H; Smith, LE; Bilsky, EJ; Davis, P; Rice, KC National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009146 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009146&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9875568 103922203 CHEMBL26575 ZINC95608617 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50768762 CCN(CC)C(=O)c1ccc(cc1)[C@H](N1C[C@H](C)N(CC=C)C[C@H]1C)c1cccc(OC)c1 InChI=1S/C28H39N3O2/c1-7-17-30-19-22(5)31(20-21(30)4)27(25-11-10-12-26(18-25)33-6)23-13-15-24(16-14-23)28(32)29(8-2)9-3/h7,10-16,18,21-22,27H,1,8-9,17,19-20H2,2-6H3/t21-,22+,27-/m0/s1 KQWVAUSXZDRQPZ-XXAUWVGASA-N 50039024 4-[(S)-((2R,5S)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::CHEMBL65648::cid_16219954 Mu-type opioid receptor Cavia cutleri 5457 ChEMBL 10.1021/jm00040a002 10.7270/Q2ZG6SWK 8035418 Calderon, SN; Rothman, RB; Porreca, F; Flippen-Anderson, JL; McNutt, RW; Xu, H; Smith, LE; Bilsky, EJ; Davis, P; Rice, KC National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039024&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 398116 103946287 CHEMBL65648 ZINC19371672 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50768780 CCN(CC)C(=O)c1ccc(cc1)C(N1CC(C)N(CC=C)CC1C)c1cccc(O)c1 InChI=1S/C27H37N3O2/c1-6-16-29-18-21(5)30(19-20(29)4)26(24-10-9-11-25(31)17-24)22-12-14-23(15-13-22)27(32)28(7-2)8-3/h6,9-15,17,20-21,26,31H,1,7-8,16,18-19H2,2-5H3 LBLDMHBSVIVJPM-UHFFFAOYSA-N 50039028 4-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-hydroxy-phenyl)-methyl]-N,N-diethyl-benzamide::CHEMBL303855 Mu-type opioid receptor Cavia cutleri 143 ChEMBL 10.1021/jm00040a002 10.7270/Q2ZG6SWK 8035418 Calderon, SN; Rothman, RB; Porreca, F; Flippen-Anderson, JL; McNutt, RW; Xu, H; Smith, LE; Bilsky, EJ; Davis, P; Rice, KC National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039028&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 2494 103946291 CHEMBL303855 ZINC22034052 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50769531 CN([C@H](CN1CCCC1)c1ccc(cc1)N=C=S)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C22H23Cl2N3OS/c1-26(22(28)13-16-4-9-19(23)20(24)12-16)21(14-27-10-2-3-11-27)17-5-7-18(8-6-17)25-15-29/h4-9,12,21H,2-3,10-11,13-14H2,1H3/t21-/m1/s1 GJRRIUVXFQLNIK-OAQYLSRUSA-N 50035473 2-(3,4-Dichloro-phenyl)-N-[(S)-1-(4-isothiocyanato-phenyl)-2-pyrrolidin-1-yl-ethyl]-N-methyl-acetamide::CHEMBL95654 Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm00044a006 10.7270/Q2513ZVF 8071934 Weerawarna, SA; Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035473&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10026663 103943491 CHEMBL95654 ZINC13738413 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50769536 CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1cc(Cl)c(Cl)cc1N=C=S InChI=1S/C22H23Cl2N3OS/c1-26(21(14-27-9-5-6-10-27)16-7-3-2-4-8-16)22(28)12-17-11-18(23)19(24)13-20(17)25-15-29/h2-4,7-8,11,13,21H,5-6,9-10,12,14H2,1H3/t21-/m1/s1 NSJVYGCMDQRINS-OAQYLSRUSA-N 50039970 2-(4,5-Dichloro-2-isothiocyanato-phenyl)-N-methyl-N-((S)-1-phenyl-2-pyrrolidin-1-yl-ethyl)-acetamide::CHEMBL95001 Mu-type opioid receptor Cavia cutleri 1250 ChEMBL 10.1021/jm00044a006 10.7270/Q2513ZVF 8071934 Weerawarna, SA; Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039970 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039970&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10366385 103947165 CHEMBL95001 ZINC13738412 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50769555 CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C21H24Cl2N2O/c1-24(21(26)14-16-9-10-18(22)19(23)13-16)20(15-25-11-5-6-12-25)17-7-3-2-4-8-17/h2-4,7-10,13,20H,5-6,11-12,14-15H2,1H3/t20-/m1/s1 AEJOEPSMZCEYJN-HXUWFJFHSA-N 50007344 (S)-2-(3,4-Dichloro-phenyl)-N-methyl-N-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-acetamide(ICI 199441)::(S)-2-(3,4-dichlorophenyl)-N-methyl-N-(1-phenyl-2-(pyrrolidin-1-yl)ethyl)acetamide::2-(3,4-Dichloro-phenyl)-N-methyl-N-((S)-1-phenyl-2-pyrrolidin-1-yl-ethyl)-acetamide::2-(3,4-Dichloro-phenyl)-N-methyl-N-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-acetamide::CHEMBL38576::ICI-199441 Mu-type opioid receptor Cavia cutleri 150 ChEMBL 10.1021/jm00044a006 10.7270/Q2513ZVF 8071934 Weerawarna, SA; Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007344&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3082718 103920619 CHEMBL38576 ZINC00607289 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50769556 CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1cccc(c1)N=C=S InChI=1S/C22H25N3OS/c1-24(22(26)15-18-8-7-11-20(14-18)23-17-27)21(16-25-12-5-6-13-25)19-9-3-2-4-10-19/h2-4,7-11,14,21H,5-6,12-13,15-16H2,1H3/t21-/m1/s1 AQNKJLVANZELEX-OAQYLSRUSA-N 50039968 2-(3-Isothiocyanato-phenyl)-N-methyl-N-((S)-1-phenyl-2-pyrrolidin-1-yl-ethyl)-acetamide::CHEMBL97246 Mu-type opioid receptor Cavia cutleri 5100 ChEMBL 10.1021/jm00044a006 10.7270/Q2513ZVF 8071934 Weerawarna, SA; Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039968 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039968&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10022640 103947163 CHEMBL97246 ZINC13738410 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50769557 CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1ccccc1 InChI=1S/C21H26N2O/c1-22(21(24)16-18-10-4-2-5-11-18)20(17-23-14-8-9-15-23)19-12-6-3-7-13-19/h2-7,10-13,20H,8-9,14-17H2,1H3/t20-/m1/s1 OVZWUDZIAAHNFG-HXUWFJFHSA-N 50039966 1-[(S)-2-(Methyl-phenylacetyl-amino)-2-phenyl-ethyl]-pyrrolidinium::CHEMBL94734::N-Methyl-2-phenyl-N-((S)-1-phenyl-2-pyrrolidin-1-yl-ethyl)-acetamide Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm00044a006 10.7270/Q2513ZVF 8071934 Weerawarna, SA; Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039966 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039966&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 190901 103947161 CHEMBL94734 ZINC00005739 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50769561 CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1ccc(cc1)N=C=S InChI=1S/C22H25N3OS/c1-24(22(26)15-18-9-11-20(12-10-18)23-17-27)21(16-25-13-5-6-14-25)19-7-3-2-4-8-19/h2-4,7-12,21H,5-6,13-16H2,1H3/t21-/m1/s1 HFZVNQMPSGSXHS-OAQYLSRUSA-N 50039967 2-(4-Isothiocyanato-phenyl)-N-methyl-N-((S)-1-phenyl-2-pyrrolidin-1-yl-ethyl)-acetamide::CHEMBL95726 Mu-type opioid receptor Cavia cutleri 730 ChEMBL 10.1021/jm00044a006 10.7270/Q2513ZVF 8071934 Weerawarna, SA; Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039967 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039967&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10339691 103947162 CHEMBL95726 ZINC13738411 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50769565 CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1ccccc1N=C=S InChI=1S/C22H25N3OS/c1-24(22(26)15-19-11-5-6-12-20(19)23-17-27)21(16-25-13-7-8-14-25)18-9-3-2-4-10-18/h2-6,9-12,21H,7-8,13-16H2,1H3/t21-/m1/s1 KESWGPUNXUMNMF-OAQYLSRUSA-N 50039969 2-(2-Isothiocyanato-phenyl)-N-methyl-N-((S)-1-phenyl-2-pyrrolidin-1-yl-ethyl)-acetamide::CHEMBL97392 Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm00044a006 10.7270/Q2513ZVF 8071934 Weerawarna, SA; Davis, RD; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039969 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039969&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10068300 103947164 CHEMBL97392 ZINC13738409 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50792708 CCN(CC)C(=O)c1ccc(cc1)C(N1CCN(CC=C)CC1)c1cccc(OC)c1 InChI=1S/C26H35N3O2/c1-5-15-27-16-18-29(19-17-27)25(23-9-8-10-24(20-23)31-4)21-11-13-22(14-12-21)26(30)28(6-2)7-3/h5,8-14,20,25H,1,6-7,15-19H2,2-4H3 BYUQJNUSTSPWIV-UHFFFAOYSA-N 50077065 4-[(4-Allyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::CHEMBL24792::CHEMBL346625 Mu-type opioid receptor Cavia cutleri 20300 ChEMBL 10.1021/jm9903895 10.7270/Q2QJ7J0X 10639287 Zhang, X; Rice, KC; Calderon, SN; Kayakiri, H; Smith, L; Coop, A; Jacobson, AE; Rothman, RB; Davis, P; Dersch, CM; Porreca, F National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077065&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 398115 103969904 CHEMBL346625CHEMBL24792 ZINC22870996 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50792717 CCN(CC)C(=O)c1ccc(cc1)[C@@H](N1C[C@@H](C)N(CC=C)C[C@@H]1C)c1cccc(OC)c1 InChI=1S/C28H39N3O2/c1-7-17-30-19-22(5)31(20-21(30)4)27(25-11-10-12-26(18-25)33-6)23-13-15-24(16-14-23)28(32)29(8-2)9-3/h7,10-16,18,21-22,27H,1,8-9,17,19-20H2,2-6H3/t21-,22+,27-/m1/s1 KQWVAUSXZDRQPZ-UMTXDNHDSA-N 50039029 (+)-4-((alpha R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-methoxyphenyl)methyl)-N,N-diethylbenzamide::(+)-4-[(alpha-R)-alpha-[2S,5R]-4-allyl[2,5-dimethyl-1-piperazinyl]-3-methoxybenzyl]-N,N-diethylbenzamide::3-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(4-diethylcarbamoyl-phenyl)-methyl]-benzoic acid::4-((R)-((2R,5S)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-methoxyphenyl)methyl)-N,N-diethylbenzamide::4-((R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-methoxyphenyl)methyl)-N,N-diethylbenzamide::4-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide (SNC 80)::4-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide(SNC-80)::4-[(R)-((2R,5S)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-((R)-4-(S)-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-[(2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl](3-methoxyphenyl)-methyl]-N,N-diethylbenzamide::CHEMBL13470::SNC-80 Mu-type opioid receptor Cavia cutleri 5450 ChEMBL 10.1021/jm9903895 10.7270/Q2QJ7J0X 10639287 Zhang, X; Rice, KC; Calderon, SN; Kayakiri, H; Smith, L; Coop, A; Jacobson, AE; Rothman, RB; Davis, P; Dersch, CM; Porreca, F National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039029&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 123924 103946292 CHEMBL13470 1611 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50792726 CCN(CC)C(=O)c1ccc(cc1)C(N1CCN(Cc2ccccc2)CC1)c1ccccc1 InChI=1S/C29H35N3O/c1-3-31(4-2)29(33)27-17-15-26(16-18-27)28(25-13-9-6-10-14-25)32-21-19-30(20-22-32)23-24-11-7-5-8-12-24/h5-18,28H,3-4,19-23H2,1-2H3 PRARFSGCMXWAAS-UHFFFAOYSA-N 50084252 4-[(4-Benzyl-piperazin-1-yl)-phenyl-methyl]-N,N-diethyl-benzamide; oxalic acid::CHEMBL150609 Mu-type opioid receptor Cavia cutleri 9850 ChEMBL 10.1021/jm9903895 10.7270/Q2QJ7J0X 10639287 Zhang, X; Rice, KC; Calderon, SN; Kayakiri, H; Smith, L; Coop, A; Jacobson, AE; Rothman, RB; Davis, P; Dersch, CM; Porreca, F National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50084252 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50084252&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10366038 103983821 CHEMBL150609 ZINC22939514 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50792753 CCN(CC)C(=O)c1ccc(cc1)C(=C1CCNCC1)c1cccc(OC)c1 InChI=1S/C24H30N2O2/c1-4-26(5-2)24(27)20-11-9-18(10-12-20)23(19-13-15-25-16-14-19)21-7-6-8-22(17-21)28-3/h6-12,17,25H,4-5,13-16H2,1-3H3 UWERJSHTOGBZDV-UHFFFAOYSA-N 50084244 CHEMBL542267::N,N-Diethyl-4-[(3-methoxy-phenyl)-piperidin-4-ylidene-methyl]-benzamide; hydrochloride Mu-type opioid receptor Cavia cutleri 27700 ChEMBL 10.1021/jm9903895 10.7270/Q2QJ7J0X 10639287 Zhang, X; Rice, KC; Calderon, SN; Kayakiri, H; Smith, L; Coop, A; Jacobson, AE; Rothman, RB; Davis, P; Dersch, CM; Porreca, F National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50084244 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50084244&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 23435898 103983813 CHEMBL542267 ZINC13803498 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50792756 CCN(CC)C(=O)c1ccc(cc1)C(N1C[C@@H](C)N(CC=C)C[C@@H]1C)c1ccccc1 InChI=1S/C27H37N3O/c1-6-18-29-19-22(5)30(20-21(29)4)26(23-12-10-9-11-13-23)24-14-16-25(17-15-24)27(31)28(7-2)8-3/h6,9-17,21-22,26H,1,7-8,18-20H2,2-5H3/t21-,22+,26?/m1/s1 WGIDFDFAOQVAHY-SGNGHUOJSA-N 50056543 4-[((1R,2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-phenyl-methyl]-N,N-diethyl-benzamide::4-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-phenyl-methyl]-N,N-diethyl-benzamide::4-[(S)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-phenyl-methyl]-N,N-diethyl-benzamide::CHEMBL153648 Mu-type opioid receptor Cavia cutleri 8580 ChEMBL 10.1021/jm9903895 10.7270/Q2QJ7J0X 10639287 Zhang, X; Rice, KC; Calderon, SN; Kayakiri, H; Smith, L; Coop, A; Jacobson, AE; Rothman, RB; Davis, P; Dersch, CM; Porreca, F National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056543&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44275475 103952781 CHEMBL153648 ZINC22454240 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50776060 CCN(CC)C(=O)c1ccc(cc1)[C@@H](N1C[C@@H](C)N(CC=C)C[C@@H]1C)c1cccc(OC)c1 InChI=1S/C28H39N3O2/c1-7-17-30-19-22(5)31(20-21(30)4)27(25-11-10-12-26(18-25)33-6)23-13-15-24(16-14-23)28(32)29(8-2)9-3/h7,10-16,18,21-22,27H,1,8-9,17,19-20H2,2-6H3/t21-,22+,27-/m1/s1 KQWVAUSXZDRQPZ-UMTXDNHDSA-N 50039029 (+)-4-((alpha R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-methoxyphenyl)methyl)-N,N-diethylbenzamide::(+)-4-[(alpha-R)-alpha-[2S,5R]-4-allyl[2,5-dimethyl-1-piperazinyl]-3-methoxybenzyl]-N,N-diethylbenzamide::3-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(4-diethylcarbamoyl-phenyl)-methyl]-benzoic acid::4-((R)-((2R,5S)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-methoxyphenyl)methyl)-N,N-diethylbenzamide::4-((R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-methoxyphenyl)methyl)-N,N-diethylbenzamide::4-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide (SNC 80)::4-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide(SNC-80)::4-[(R)-((2R,5S)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-((R)-4-(S)-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-[(2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl](3-methoxyphenyl)-methyl]-N,N-diethylbenzamide::CHEMBL13470::SNC-80 Mu-type opioid receptor Cavia cutleri 5457 ChEMBL 10.1021/jm950695s 10.7270/Q2FQ9X82 8642567 Bertha, CM; Ellis, M; Flippen-Anderson, JL; Porreca, F; Rothman, RB; Davis, P; Xu, H; Becketts, K; Rice, KC National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039029&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 123924 103946292 CHEMBL13470 1611 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50776063 CN1CCC2(CC1Cc1[nH]c3ccccc3c21)c1cccc(O)c1 InChI=1S/C21H22N2O/c1-23-10-9-21(14-5-4-6-16(24)11-14)13-15(23)12-19-20(21)17-7-2-3-8-18(17)22-19/h2-8,11,15,22,24H,9-10,12-13H2,1H3 WMJAKEDTFIYKBZ-UHFFFAOYSA-N 50034600 (+) 3-[13-methyl-9,13-diazatetracyclo[10.3.1.02,10.03,8]hexadeca-2(10),3(8),4,6-tetraen-1-yl]phenol::(-) 1,2,3,4,5,11-Hexahydro-6-(2-hydroxy)phenyl-3-methyl-2,6-methano-6H-azocino[4,5-b]indole::(-) 3-[13-methyl-9,13-diazatetracyclo[10.3.1.02,10.03,8]hexadeca-2(10),3(8),4,6-tetraen-1-yl]phenol::1,2,3,4,5,11-Hexahydro-6-(2-hydroxy)phenyl-3-methyl-2,6-methano-6H-azocino[4,5-b]indole::3-[13-methyl-9,13-diazatetracyclo[10.3.1.02,10.03,8]hexadeca-2(10),3(8),4,6-tetraen-1-yl]phenol::CHEMBL290301 Mu-type opioid receptor Cavia cutleri 2073 ChEMBL 10.1021/jm950695s 10.7270/Q2FQ9X82 8642567 Bertha, CM; Ellis, M; Flippen-Anderson, JL; Porreca, F; Rothman, RB; Davis, P; Xu, H; Becketts, K; Rice, KC National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034600 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034600&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44285619 103942766 CHEMBL290301 ZINC13741135 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50809093 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)N[C@@H](CC(N)=O)C(O)=O InChI=1S/C25H30N4O6/c1-13-7-17(30)8-14(2)18(13)10-19(26)24(33)29-12-16-6-4-3-5-15(16)9-21(29)23(32)28-20(25(34)35)11-22(27)31/h3-8,19-21,30H,9-12,26H2,1-2H3,(H2,27,31)(H,28,32)(H,34,35)/t19-,20-,21?/m0/s1 GKMIMMIVGJGXPV-AHTKWCMKSA-N 50121644 2-({2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-succinamic acid Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm020336e 10.7270/Q2BR8SWH 12459023 Balboni, G; Salvadori, S; Guerrini, R; Negri, L; Giannini, E; Jinsmaa, Y; Bryant, SD; Lazarus, LH University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50121644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50121644&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44368436 104014436 ZINC27644096 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50809097 C[C@H](NC(=O)C1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)c1nc2ccccc2[nH]1 InChI=1S/C30H33N5O3/c1-17-12-22(36)13-18(2)23(17)15-24(31)30(38)35-16-21-9-5-4-8-20(21)14-27(35)29(37)32-19(3)28-33-25-10-6-7-11-26(25)34-28/h4-13,19,24,27,36H,14-16,31H2,1-3H3,(H,32,37)(H,33,34)/t19-,24-,27?/m0/s1 BSHPERRUISLIDL-FBIFJVEVSA-N 50121645 2-[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]-N-[(1S)-1-(1H-1,3-benzodiazol-2-yl)ethyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid [1-(1H-benzoimidazol-2-yl)-ethyl]-amide Mu-type opioid receptor Cavia cutleri 6.360 ChEMBL 10.1021/jm020336e 10.7270/Q2BR8SWH 12459023 Balboni, G; Salvadori, S; Guerrini, R; Negri, L; Giannini, E; Jinsmaa, Y; Bryant, SD; Lazarus, LH University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50121645 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50121645&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44368369 104014437 ZINC27639518 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50809098 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O InChI=1S/C40H50N8O10/c1-23(44-37(55)29(41)18-25-9-13-27(50)14-10-25)36(54)46-30(19-24-6-3-2-4-7-24)38(56)43-21-34(52)45-31(20-26-11-15-28(51)16-12-26)40(58)48-17-5-8-33(48)39(57)47-32(22-49)35(42)53/h2-4,6-7,9-16,23,29-33,49-51H,5,8,17-22,41H2,1H3,(H2,42,53)(H,43,56)(H,44,55)(H,45,52)(H,46,54)(H,47,57)/t23-,29+,30+,31+,32+,33+/m1/s1 FHZPGIUBXYVUOY-VWGYHWLBSA-N 50059841 (S)-1-[(S)-2-[2-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid ((S)-1-carbamoyl-2-hydroxy-ethyl)-amide::(S)-2-Amino-N-{(R)-1-[(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethylcarbamoyl]-ethyl}-3-(4-hydroxy-phenyl)-propionamide::1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide::1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide (Dermorphin)::1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide(Dermorphin)::CHEMBL278789::DERMORPHIN::Dermorphin;1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide::H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2::Tyr-Ala-Phe-Gly-Tyr-Pro-Ser::YAFGYPS-NH2 Mu-type opioid receptor Cavia cutleri 1.21 ChEMBL 10.1021/jm020336e 10.7270/Q2BR8SWH 12459023 Balboni, G; Salvadori, S; Guerrini, R; Negri, L; Giannini, E; Jinsmaa, Y; Bryant, SD; Lazarus, LH University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059841 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059841&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5485199 103955620 CHEMBL278789 ZINC95548678 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50809100 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)NCCc1nc2ccccc2[nH]1 InChI=1S/C30H33N5O3/c1-18-13-22(36)14-19(2)23(18)16-24(31)30(38)35-17-21-8-4-3-7-20(21)15-27(35)29(37)32-12-11-28-33-25-9-5-6-10-26(25)34-28/h3-10,13-14,24,27,36H,11-12,15-17,31H2,1-2H3,(H,32,37)(H,33,34)/t24-,27?/m0/s1 DANFDLDCLSODGV-BXXZMZEQSA-N 50108919 2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid [2-(1H-benzoimidazol-2-yl)-ethyl]-amide Mu-type opioid receptor Cavia cutleri 107.5 ChEMBL 10.1021/jm020336e 10.7270/Q2BR8SWH 12459023 Balboni, G; Salvadori, S; Guerrini, R; Negri, L; Giannini, E; Jinsmaa, Y; Bryant, SD; Lazarus, LH University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108919 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108919&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44368342 104004057 ZINC27627665 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50809101 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)N[C@@H](Cc1nc2ccccc2[nH]1)C(O)=O InChI=1S/C31H33N5O5/c1-17-11-21(37)12-18(2)22(17)14-23(32)30(39)36-16-20-8-4-3-7-19(20)13-27(36)29(38)35-26(31(40)41)15-28-33-24-9-5-6-10-25(24)34-28/h3-12,23,26-27,37H,13-16,32H2,1-2H3,(H,33,34)(H,35,38)(H,40,41)/t23-,26-,27?/m0/s1 JXFPKICARFQMQZ-UDMWCJJBSA-N 50121648 2-({2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-3-(1H-benzoimidazol-2-yl)-propionic acid Mu-type opioid receptor Cavia cutleri 1558 ChEMBL 10.1021/jm020336e 10.7270/Q2BR8SWH 12459023 Balboni, G; Salvadori, S; Guerrini, R; Negri, L; Giannini, E; Jinsmaa, Y; Bryant, SD; Lazarus, LH University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50121648 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50121648&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44367783 104014440 ZINC27632011 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50809104 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)NCc1nc2ccccc2n1C(O)=O InChI=1S/C30H31N5O5/c1-17-11-21(36)12-18(2)22(17)14-23(31)29(38)34-16-20-8-4-3-7-19(20)13-26(34)28(37)32-15-27-33-24-9-5-6-10-25(24)35(27)30(39)40/h3-12,23,26,36H,13-16,31H2,1-2H3,(H,32,37)(H,39,40)/t23-,26?/m0/s1 DXOXCVOYUDIQCK-ZZHFZYNASA-N 50121649 2-[({2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-methyl]-benzoimidazole-1-carboxylic acid Mu-type opioid receptor Cavia cutleri 3193 ChEMBL 10.1021/jm020336e 10.7270/Q2BR8SWH 12459023 Balboni, G; Salvadori, S; Guerrini, R; Negri, L; Giannini, E; Jinsmaa, Y; Bryant, SD; Lazarus, LH University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50121649 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50121649&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44368408 104014441 ZINC27641210 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50809105 C[C@H](NC(=O)C1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(N)=O InChI=1S/C24H30N4O4/c1-13-8-18(29)9-14(2)19(13)11-20(25)24(32)28-12-17-7-5-4-6-16(17)10-21(28)23(31)27-15(3)22(26)30/h4-9,15,20-21,29H,10-12,25H2,1-3H3,(H2,26,30)(H,27,31)/t15-,20-,21?/m0/s1 XLVQVCOZHAPLOB-XABNSEFBSA-N 50108918 (2S)-2-({2-[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]-1,2,3,4-tetrahydroisoquinolin-3-yl}formamido)propanamide::2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid (1-carbamoyl-ethyl)-amide Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm020336e 10.7270/Q2BR8SWH 12459023 Balboni, G; Salvadori, S; Guerrini, R; Negri, L; Giannini, E; Jinsmaa, Y; Bryant, SD; Lazarus, LH University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108918&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44367842 104004056 ZINC27634717 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50809109 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(O)=O InChI=1S/C37H51N7O11/c1-19(2)30(36(54)39-18-29(48)49)44-37(55)31(20(3)4)43-35(53)27(17-28(46)47)42-34(52)26(16-22-9-7-6-8-10-22)41-32(50)21(5)40-33(51)25(38)15-23-11-13-24(45)14-12-23/h6-14,19-21,25-27,30-31,45H,15-18,38H2,1-5H3,(H,39,54)(H,40,51)(H,41,50)(H,42,52)(H,43,53)(H,44,55)(H,46,47)(H,48,49)/t21-,25-,26-,27-,30-,31-/m0/s1 PQAAYVKNXWIKER-PKNMDTBHSA-N 50009145 3-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{1-[1-(carboxymethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL26861 Mu-type opioid receptor Cavia cutleri >1200 ChEMBL 10.1021/jm020336e 10.7270/Q2BR8SWH 12459023 Balboni, G; Salvadori, S; Guerrini, R; Negri, L; Giannini, E; Jinsmaa, Y; Bryant, SD; Lazarus, LH University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009145 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009145&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9832089 103922202 CHEMBL26861 ZINC95608622 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50809121 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCc1nc2ccccc2[nH]1 InChI=1S/C29H31N5O3/c1-17-11-21(35)12-18(2)22(17)14-23(30)29(37)34-16-20-8-4-3-7-19(20)13-26(34)28(36)31-15-27-32-24-9-5-6-10-25(24)33-27/h3-12,23,26,35H,13-16,30H2,1-2H3,(H,31,36)(H,32,33)/t23-,26-/m0/s1 XRZTZWCPHAJWJQ-OZXSUGGESA-N 50179191 (S)-N-((1H-benzo[d]imidazol-2-yl)methyl)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid (1H-benzoimidazol-2-ylmethyl)-amide::CHEMBL109390::H-Dmt-Tic-NH-CH2-Bid::UFP-502 Mu-type opioid receptor Cavia cutleri 40.7 ChEMBL 10.1021/jm020336e 10.7270/Q2BR8SWH 12459023 Balboni, G; Salvadori, S; Guerrini, R; Negri, L; Giannini, E; Jinsmaa, Y; Bryant, SD; Lazarus, LH University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179191&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10345770 104064419 CHEMBL109390 ZINC13472298 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50809129 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)N[C@@H](CC(O)=O)C(N)=O InChI=1S/C25H30N4O6/c1-13-7-17(30)8-14(2)18(13)10-19(26)25(35)29-12-16-6-4-3-5-15(16)9-21(29)24(34)28-20(23(27)33)11-22(31)32/h3-8,19-21,30H,9-12,26H2,1-2H3,(H2,27,33)(H,28,34)(H,31,32)/t19-,20-,21?/m0/s1 PVNQCTDTZFGLFA-AHTKWCMKSA-N 50121650 3-({2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-succinamic acid Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm020336e 10.7270/Q2BR8SWH 12459023 Balboni, G; Salvadori, S; Guerrini, R; Negri, L; Giannini, E; Jinsmaa, Y; Bryant, SD; Lazarus, LH University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50121650 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50121650&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44368459 104014442 ZINC27641221 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50809130 C[C@H](NC(=O)C1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)c1nc2ccccc2[nH]1 InChI=1S/C30H33N5O3/c1-17-12-22(36)13-18(2)23(17)15-24(31)30(38)35-16-21-9-5-4-8-20(21)14-27(35)29(37)32-19(3)28-33-25-10-6-7-11-26(25)34-28/h4-13,19,24,27,36H,14-16,31H2,1-3H3,(H,32,37)(H,33,34)/t19-,24-,27?/m0/s1 BSHPERRUISLIDL-FBIFJVEVSA-N 50121645 2-[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]-N-[(1S)-1-(1H-1,3-benzodiazol-2-yl)ethyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid [1-(1H-benzoimidazol-2-yl)-ethyl]-amide Mu-type opioid receptor Cavia cutleri 71.7 ChEMBL 10.1021/jm020336e 10.7270/Q2BR8SWH 12459023 Balboni, G; Salvadori, S; Guerrini, R; Negri, L; Giannini, E; Jinsmaa, Y; Bryant, SD; Lazarus, LH University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50121645 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50121645&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44368369 104014437 ZINC27639518 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50809134 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](CC(O)=O)c1nc2ccccc2[nH]1 InChI=1S/C31H33N5O5/c1-17-11-21(37)12-18(2)22(17)14-23(32)31(41)36-16-20-8-4-3-7-19(20)13-27(36)30(40)35-26(15-28(38)39)29-33-24-9-5-6-10-25(24)34-29/h3-12,23,26-27,37H,13-16,32H2,1-2H3,(H,33,34)(H,35,40)(H,38,39)/t23-,26-,27-/m0/s1 USVQTDLSVBRMCR-YGPDHOBYSA-N 50272169 (S)-3-((S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido)-3-(1H-benzo[d]imidazol-2-yl)propanoic acid::3-({2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-3-(1H-benzoimidazol-2-yl)-propionic acid::CHEMBL442577::H-Dmt-Tic-NH-(S)CH(CH2-COOH)-Bid::UFP-512 Mu-type opioid receptor Cavia cutleri 1724 ChEMBL 10.1021/jm020336e 10.7270/Q2BR8SWH 12459023 Balboni, G; Salvadori, S; Guerrini, R; Negri, L; Giannini, E; Jinsmaa, Y; Bryant, SD; Lazarus, LH University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50272169 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50272169&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10918703 104116657 CHEMBL442577 ZINC27631810 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50809136 C[C@H](NC(=O)C1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(N)=O InChI=1S/C24H30N4O4/c1-13-8-18(29)9-14(2)19(13)11-20(25)24(32)28-12-17-7-5-4-6-16(17)10-21(28)23(31)27-15(3)22(26)30/h4-9,15,20-21,29H,10-12,25H2,1-3H3,(H2,26,30)(H,27,31)/t15-,20-,21?/m0/s1 XLVQVCOZHAPLOB-XABNSEFBSA-N 50108918 (2S)-2-({2-[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]-1,2,3,4-tetrahydroisoquinolin-3-yl}formamido)propanamide::2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid (1-carbamoyl-ethyl)-amide Mu-type opioid receptor Cavia cutleri 4740 ChEMBL 10.1021/jm020336e 10.7270/Q2BR8SWH 12459023 Balboni, G; Salvadori, S; Guerrini, R; Negri, L; Giannini, E; Jinsmaa, Y; Bryant, SD; Lazarus, LH University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108918&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44367842 104004056 ZINC27634717 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50794085 C[C@H]1C2N(CC3CCCO3)CC[C@]1(C)c1cc(O)ccc1C2=O InChI=1S/C19H25NO3/c1-12-17-18(22)15-6-5-13(21)10-16(15)19(12,2)7-8-20(17)11-14-4-3-9-23-14/h5-6,10,12,14,17,21H,3-4,7-9,11H2,1-2H3/t12-,14?,17?,19-/m0/s1 GNMQONOQCCJUIP-CRXFJISLSA-N 50083924 8-Hydroxy-6,11-dimethyl-3-(tetrahydro-furan-2-ylmethyl)-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::CHEMBL280958 Mu-type opioid receptor Cavia cutleri 2900 ChEMBL 10.1021/jm9903343 10.7270/Q20V8DGH 10633042 Neumeyer, JL; Bidlack, JM; Zong, R; Bakthavachalam, V; Gao, P; Cohen, DJ; Negus, SS; Mello, NK Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083924&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44273237 103983525 CHEMBL280958 ZINC28228325 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50794098 CN1CC[C@]23CCCC[C@H]2[C@H]1Cc1ccc(O)cc31 InChI=1S/C17H23NO/c1-18-9-8-17-7-3-2-4-14(17)16(18)10-12-5-6-13(19)11-15(12)17/h5-6,11,14,16,19H,2-4,7-10H2,1H3/t14-,16+,17+/m0/s1 JAQUASYNZVUNQP-USXIJHARSA-N 50369518 LEVORPHANOL HYDROCHLORIDE Mu-type opioid receptor Cavia cutleri 0.210000 ChEMBL 10.1021/jm9903343 10.7270/Q20V8DGH 10633042 Neumeyer, JL; Bidlack, JM; Zong, R; Bakthavachalam, V; Gao, P; Cohen, DJ; Negus, SS; Mello, NK Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369518&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5359272 160848620 DB00854 C08014 ZINC03812984 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50794100 CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C19H26Cl2N2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17-,18-/m1/s1 VQLPLYSROCPWFF-QZTJIDSGSA-N 50000296 CHEMBL441765::CHEMBL482811::U-50488H::US11492374, ID 1 Mu-type opioid receptor Cavia cutleri 220 ChEMBL 10.1021/jm9903343 10.7270/Q20V8DGH 10633042 Neumeyer, JL; Bidlack, JM; Zong, R; Bakthavachalam, V; Gao, P; Cohen, DJ; Negus, SS; Mello, NK Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000296&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036289 103914903 73358 CHEMBL482811CHEMBL441765 1654 C11796 ZINC00643032 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50794101 CC[C@]12CCN(CC3CC3)C([C@@H]1C)C(=O)c1ccc(O)cc21 InChI=1S/C19H25NO2/c1-3-19-8-9-20(11-13-4-5-13)17(12(19)2)18(22)15-7-6-14(21)10-16(15)19/h6-7,10,12-13,17,21H,3-5,8-9,11H2,1-2H3/t12-,17?,19-/m0/s1 SEJUQQOPVAUETF-BKBNBNODSA-N 50000091 (6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::(6S,11R)-3-Cyclopropylmethyl-9-hydroxy-6,11-dimethyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one (ethylketocyclazocine)::3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one(Ethylketazocine, EKC)::CHEMBL279968::EKC::EKC(-) Mu-type opioid receptor Cavia cutleri 0.780000 ChEMBL 10.1021/jm9903343 10.7270/Q20V8DGH 10633042 Neumeyer, JL; Bidlack, JM; Zong, R; Bakthavachalam, V; Gao, P; Cohen, DJ; Negus, SS; Mello, NK Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000091&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44273397 103914788 CHEMBL279968 ZINC00967957 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50794104 Oc1ccc2C(=O)C3C4CCCCC4(CCN3CC3CCCO3)c2c1 InChI=1S/C21H27NO3/c23-14-6-7-16-18(12-14)21-8-2-1-5-17(21)19(20(16)24)22(10-9-21)13-15-4-3-11-25-15/h6-7,12,15,17,19,23H,1-5,8-11,13H2 BSCRKXLANCGZGY-UHFFFAOYSA-N 50369519 CHEMBL1202427 Mu-type opioid receptor Cavia cutleri 0.380000 ChEMBL 10.1021/jm9903343 10.7270/Q20V8DGH 10633042 Neumeyer, JL; Bidlack, JM; Zong, R; Bakthavachalam, V; Gao, P; Cohen, DJ; Negus, SS; Mello, NK Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369519 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369519&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44273399 160848621 CHEMBL1202427 ZINC36221727 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50794105 Oc1ccc2C[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CCC3)c2c1 InChI=1S/C21H29NO/c23-17-8-7-16-12-20-18-6-1-2-9-21(18,19(16)13-17)10-11-22(20)14-15-4-3-5-15/h7-8,13,15,18,20,23H,1-6,9-12,14H2/t18-,20+,21+/m0/s1 YSTAPDGDOHWKQR-CEWLAPEOSA-N 50135808 (-)-3-Hydroxy-N-cyclobutylmethylmorphinan S(+)-Mandelate::17-cyclobutylmethyl-(1R,9R,10R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol::3-Hydroxy-N-cyclobutylmethylmorphinan::BUTORPHAN::CHEMBL301160::MCL-101 Mu-type opioid receptor Cavia cutleri 0.120000 ChEMBL 10.1021/jm9903343 10.7270/Q20V8DGH 10633042 Neumeyer, JL; Bidlack, JM; Zong, R; Bakthavachalam, V; Gao, P; Cohen, DJ; Negus, SS; Mello, NK Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50135808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50135808&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9804450 104026158 CHEMBL301160 ZINC03982790 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50794111 Oc1ccc2C[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CC3)c2c1 InChI=1S/C20H27NO/c22-16-7-6-15-11-19-17-3-1-2-8-20(17,18(15)12-16)9-10-21(19)13-14-4-5-14/h6-7,12,14,17,19,22H,1-5,8-11,13H2/t17-,19+,20+/m0/s1 NLBUEDSBXVNAPB-DFQSSKMNSA-N 50135800 (-)-3-Hydroxy-N-cycloproypylmethylmorphinan Mandelate::17-cyclopropylmethyl-(1R,9R,10R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol::3-Hydroxy-N-cyclopropylmethylmorphinan::CHEMBL49269::CYCLORPHAN::US10231963, Table B.6::US10736890, Compound TABLE B.6::US11534436, Compound Table B.6::US9656961, Example 00123 Mu-type opioid receptor Cavia cutleri 0.092000 ChEMBL 10.1021/jm9903343 10.7270/Q20V8DGH 10633042 Neumeyer, JL; Bidlack, JM; Zong, R; Bakthavachalam, V; Gao, P; Cohen, DJ; Negus, SS; Mello, NK Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50135800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50135800&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5359966 104026150 CHEMBL49269 ZINC04215487 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50794114 Oc1ccc2C(=O)C3C4CCCCC4(CCN3CC3CC3)c2c1 InChI=1S/C20H25NO2/c22-14-6-7-15-17(11-14)20-8-2-1-3-16(20)18(19(15)23)21(10-9-20)12-13-4-5-13/h6-7,11,13,16,18,22H,1-5,8-10,12H2 GBFZDUXAYHZNHA-UHFFFAOYSA-N 50369520 CHEMBL1202425 Mu-type opioid receptor Cavia cutleri 240 ChEMBL 10.1021/jm9903343 10.7270/Q20V8DGH 10633042 Neumeyer, JL; Bidlack, JM; Zong, R; Bakthavachalam, V; Gao, P; Cohen, DJ; Negus, SS; Mello, NK Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369520 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369520&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44273377 160848622 CHEMBL1202425 ZINC36221725 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50802155 CCCCN1CCN(C(C1)[C@H](C)N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C22H33Cl2N3O/c1-3-4-9-25-12-13-27(21(16-25)17(2)26-10-5-6-11-26)22(28)15-18-7-8-19(23)20(24)14-18/h7-8,14,17,21H,3-6,9-13,15-16H2,1-2H3/t17-,21?/m0/s1 GXELPJLAYDYLJB-PBVYKCSPSA-N 50102806 1-[4-Butyl-2-(1-pyrrolidin-1-yl-ethyl)-piperazin-1-yl]-2-(3,4-dichloro-phenyl)-ethanone::CHEMBL319835 Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm0108395 10.7270/Q2SN09NJ 11495592 Soukara, S; Maier, CA; Predoiu, U; Ehret, A; Jackisch, R; Wunsch, B Pharmazeutisches Institut der Universit£t Freiburg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102806&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44328180 103999241 CHEMBL319835 ZINC26723282 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50802161 CCCCN1CCN(C(C1)[C@@H](C)N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C22H33Cl2N3O/c1-3-4-9-25-12-13-27(21(16-25)17(2)26-10-5-6-11-26)22(28)15-18-7-8-19(23)20(24)14-18/h7-8,14,17,21H,3-6,9-13,15-16H2,1-2H3/t17-,21?/m1/s1 GXELPJLAYDYLJB-OQHSHRKDSA-N 50102811 1-[4-Butyl-2-(1-pyrrolidin-1-yl-ethyl)-piperazin-1-yl]-2-(3,4-dichloro-phenyl)-ethanone::CHEMBL97051 Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm0108395 10.7270/Q2SN09NJ 11495592 Soukara, S; Maier, CA; Predoiu, U; Ehret, A; Jackisch, R; Wunsch, B Pharmazeutisches Institut der Universit£t Freiburg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102811 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102811&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44328157 103999246 CHEMBL97051 ZINC26723727 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50802175 C[C@@H](C1CN(CCN1C(=O)Cc1ccc(Cl)c(Cl)c1)c1ccccc1)N1CCCC1 InChI=1S/C24H29Cl2N3O/c1-18(27-11-5-6-12-27)23-17-28(20-7-3-2-4-8-20)13-14-29(23)24(30)16-19-9-10-21(25)22(26)15-19/h2-4,7-10,15,18,23H,5-6,11-14,16-17H2,1H3/t18-,23?/m0/s1 OYRXYIUNONBFEX-XNUZUHMRSA-N 50102813 2-(3,4-Dichloro-phenyl)-1-[4-phenyl-2-(1-pyrrolidin-1-yl-ethyl)-piperazin-1-yl]-ethanone::CHEMBL94320 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm0108395 10.7270/Q2SN09NJ 11495592 Soukara, S; Maier, CA; Predoiu, U; Ehret, A; Jackisch, R; Wunsch, B Pharmazeutisches Institut der Universit£t Freiburg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102813 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102813&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44328133 103999248 CHEMBL94320 ZINC26674088 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50802195 Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1 UZHSEJADLWPNLE-GRGSLBFTSA-N 50000788 (morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(naloxone) 4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::(naloxone)4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::(naloxone)4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one (naloxone)::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one( Naloxone)::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(Naxolone)::4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(naloxone)C2H2O4::Analog of 14-(Arylhydroxyamino)codeinone::NALOXONE::NARCAN::SUBOXONE::[17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydroxymorphinan-6-one Mu-type opioid receptor Cavia cutleri 0.680 ChEMBL 10.1021/jm0108395 10.7270/Q2SN09NJ 11495592 Soukara, S; Maier, CA; Predoiu, U; Ehret, A; Jackisch, R; Wunsch, B Pharmazeutisches Institut der Universit£t Freiburg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000788&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5284596 103915330 7459 DB01183 1676 C07252 ZINC00389747 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50802205 C[C@H](C1CN(CCN1C(=O)Cc1ccc(Cl)c(Cl)c1)c1ccccc1)N1CCCC1 InChI=1S/C24H29Cl2N3O/c1-18(27-11-5-6-12-27)23-17-28(20-7-3-2-4-8-20)13-14-29(23)24(30)16-19-9-10-21(25)22(26)15-19/h2-4,7-10,15,18,23H,5-6,11-14,16-17H2,1H3/t18-,23?/m1/s1 OYRXYIUNONBFEX-FKSKYRLFSA-N 50102814 2-(3,4-Dichloro-phenyl)-1-[4-phenyl-2-(1-pyrrolidin-1-yl-ethyl)-piperazin-1-yl]-ethanone::CHEMBL97590 Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm0108395 10.7270/Q2SN09NJ 11495592 Soukara, S; Maier, CA; Predoiu, U; Ehret, A; Jackisch, R; Wunsch, B Pharmazeutisches Institut der Universit£t Freiburg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102814 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102814&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44328124 103999249 CHEMBL97590 ZINC26720536 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50802348 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CCc1c(C)cc(O)cc1C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C75H118N22O14/c1-8-43(4)62(71(110)93-55(23-16-34-86-75(82)83)72(111)97-35-17-24-59(97)70(109)90-52(63(77)102)20-12-13-31-76)96-67(106)54(22-15-33-85-74(80)81)91-66(105)53(21-14-32-84-73(78)79)92-68(107)56(36-42(2)3)95-69(108)58(39-47-18-10-9-11-19-47)94-64(103)46(7)88-61(101)41-87-65(104)57(40-48-25-27-49(98)28-26-48)89-60(100)30-29-51-44(5)37-50(99)38-45(51)6/h9-11,18-19,25-28,37-38,42-43,46,52-59,62,98-99H,8,12-17,20-24,29-36,39-41,76H2,1-7H3,(H2,77,102)(H,87,104)(H,88,101)(H,89,100)(H,90,109)(H,91,105)(H,92,107)(H,93,110)(H,94,103)(H,95,108)(H,96,106)(H4,78,79,84)(H4,80,81,85)(H4,82,83,86)/t43-,46-,52-,53-,54-,55-,56-,57-,58-,59-,62-/m0/s1 JWNVVACRXGNHPU-VYIWQZPZSA-N 50103974 CHEMBL414068::[Dhp1,D-Ala3]Dyn A(1-11)-NH2 Mu-type opioid receptor Cavia cutleri 73 ChEMBL 10.1021/jm0101186 10.7270/Q28K79SN 11543672 Lu, Y; Nguyen, TM; Weltrowska, G; Berezowska, I; Lemieux, C; Chung, NN; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103974&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44334303 103999960 CHEMBL414068 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50802353 CC[C@H](C)[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](C)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C66H109N21O12/c1-8-38(4)54(62(98)84-48(23-16-28-77-66(73)74)63(99)87-29-17-24-51(87)61(97)81-45(55(68)91)20-12-13-25-67)86-58(94)47(22-15-27-76-65(71)72)82-57(93)46(21-14-26-75-64(69)70)83-59(95)49(30-37(2)3)85-60(96)50(34-42-18-10-9-11-19-42)80-53(90)36-78-52(89)35-79-56(92)41(7)33-44-39(5)31-43(88)32-40(44)6/h9-11,18-19,31-32,37-38,41,45-51,54,88H,8,12-17,20-30,33-36,67H2,1-7H3,(H2,68,91)(H,78,89)(H,79,92)(H,80,90)(H,81,97)(H,82,93)(H,83,95)(H,84,98)(H,85,96)(H,86,94)(H4,69,70,75)(H4,71,72,76)(H4,73,74,77)/t38-,41-,45-,46-,47-,48-,49-,50-,51-,54-/m0/s1 ZLVUENKUDNMVML-XKPZCRAXSA-N 50252860 (S)-N-((S)-1,6-diamino-1-oxohexan-2-yl)-1-((S)-5-guanidino-2-((2S,3S)-2-((S)-5-guanidino-2-((S)-5-guanidino-2-((S)-2-((S)-2-(2-(2-((S)-3-(4-hydroxy-2,6-dimethylphenyl)-2-methylpropanamido)acetamido)acetamido)-3-phenylpropanamido)-4-methylpentanamido)pentanamido)pentanamido)-3-methylpentanamido)pentanoyl)pyrrolidine-2-carboxamide::CHEMBL506821::[(2S)-Mdp1]Dyn A(1-11)-NH2 Mu-type opioid receptor Cavia cutleri 213 ChEMBL 10.1021/jm0101186 10.7270/Q28K79SN 11543672 Lu, Y; Nguyen, TM; Weltrowska, G; Berezowska, I; Lemieux, C; Chung, NN; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252860&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10034436 104105582 CHEMBL506821 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50802355 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CCc1c(C)cc(O)cc1C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C74H116N22O14/c1-7-43(4)62(70(109)93-54(22-15-33-85-74(81)82)71(110)96-34-16-23-58(96)69(108)90-51(63(76)102)19-11-12-30-75)95-66(105)53(21-14-32-84-73(79)80)91-65(104)52(20-13-31-83-72(77)78)92-67(106)55(35-42(2)3)94-68(107)57(38-46-17-9-8-10-18-46)89-61(101)41-86-60(100)40-87-64(103)56(39-47-24-26-48(97)27-25-47)88-59(99)29-28-50-44(5)36-49(98)37-45(50)6/h8-10,17-18,24-27,36-37,42-43,51-58,62,97-98H,7,11-16,19-23,28-35,38-41,75H2,1-6H3,(H2,76,102)(H,86,100)(H,87,103)(H,88,99)(H,89,101)(H,90,108)(H,91,104)(H,92,106)(H,93,109)(H,94,107)(H,95,105)(H4,77,78,83)(H4,79,80,84)(H4,81,82,85)/t43-,51-,52-,53-,54-,55-,56-,57-,58-,62-/m0/s1 IZLSXTHBMFBNRN-DJQAJQEISA-N 50103975 CHEMBL414502::[Dhp1]Dyn A(1-11)-NH2 Mu-type opioid receptor Cavia cutleri 27.9 ChEMBL 10.1021/jm0101186 10.7270/Q28K79SN 11543672 Lu, Y; Nguyen, TM; Weltrowska, G; Berezowska, I; Lemieux, C; Chung, NN; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103975&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44334227 103999961 CHEMBL414502 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50802356 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNOC(=O)CCc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C63H103N21O13/c1-5-38(4)52(59(95)81-45(20-13-31-74-63(70)71)60(96)84-32-14-21-48(84)58(94)78-42(53(65)89)17-9-10-28-64)83-55(91)44(19-12-30-73-62(68)69)79-54(90)43(18-11-29-72-61(66)67)80-56(92)46(33-37(2)3)82-57(93)47(34-40-15-7-6-8-16-40)77-50(87)35-75-49(86)36-76-97-51(88)27-24-39-22-25-41(85)26-23-39/h6-8,15-16,22-23,25-26,37-38,42-48,52,76,85H,5,9-14,17-21,24,27-36,64H2,1-4H3,(H2,65,89)(H,75,86)(H,77,87)(H,78,94)(H,79,90)(H,80,92)(H,81,95)(H,82,93)(H,83,91)(H4,66,67,72)(H4,68,69,73)(H4,70,71,74)/t38-,42-,43-,44-,45-,46-,47-,48-,52-/m0/s1 IREKKNMJTCBISB-FQLQCWLDSA-N 50103977 CHEMBL216899::[Hpp1]Dyn A(1-11)-NH2 Mu-type opioid receptor Cavia cutleri 286 ChEMBL 10.1021/jm0101186 10.7270/Q28K79SN 11543672 Lu, Y; Nguyen, TM; Weltrowska, G; Berezowska, I; Lemieux, C; Chung, NN; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103977 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103977&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44334229 103999963 CHEMBL216899 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50802358 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C65H108N22O12/c1-7-37(4)53(61(98)84-47(22-15-27-77-65(73)74)62(99)87-28-16-23-50(87)60(97)81-44(54(68)91)19-11-12-24-66)86-57(94)46(21-14-26-76-64(71)72)82-56(93)45(20-13-25-75-63(69)70)83-58(95)48(29-36(2)3)85-59(96)49(32-40-17-9-8-10-18-40)80-52(90)35-78-51(89)34-79-55(92)43(67)33-42-38(5)30-41(88)31-39(42)6/h8-10,17-18,30-31,36-37,43-50,53,88H,7,11-16,19-29,32-35,66-67H2,1-6H3,(H2,68,91)(H,78,89)(H,79,92)(H,80,90)(H,81,97)(H,82,93)(H,83,95)(H,84,98)(H,85,96)(H,86,94)(H4,69,70,75)(H4,71,72,76)(H4,73,74,77)/t37-,43-,44-,45-,46-,47-,48-,49-,50-,53-/m0/s1 KHDAVOLOCJPTBA-RGPQWKQSSA-N 50103978 CHEMBL436911::[Dmt1]Dyn A(1-11)-NH2 Mu-type opioid receptor Cavia cutleri 0.4350 ChEMBL 10.1021/jm0101186 10.7270/Q28K79SN 11543672 Lu, Y; Nguyen, TM; Weltrowska, G; Berezowska, I; Lemieux, C; Chung, NN; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103978&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10964333 103999964 CHEMBL436911 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50802359 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C63H104N22O12/c1-5-37(4)51(59(96)82-45(20-13-29-75-63(71)72)60(97)85-30-14-21-48(85)58(95)79-42(52(66)89)17-9-10-26-64)84-55(92)44(19-12-28-74-62(69)70)80-54(91)43(18-11-27-73-61(67)68)81-56(93)46(31-36(2)3)83-57(94)47(33-38-15-7-6-8-16-38)78-50(88)35-76-49(87)34-77-53(90)41(65)32-39-22-24-40(86)25-23-39/h6-8,15-16,22-25,36-37,41-48,51,86H,5,9-14,17-21,26-35,64-65H2,1-4H3,(H2,66,89)(H,76,87)(H,77,90)(H,78,88)(H,79,95)(H,80,91)(H,81,93)(H,82,96)(H,83,94)(H,84,92)(H4,67,68,73)(H4,69,70,74)(H4,71,72,75)/t37-,41-,42-,43-,44-,45-,46-,47-,48-,51-/m0/s1 OKJAOUBQLSWUNX-QFIUEGLPSA-N 50010704 CHEMBL216640::Dyn A(1-11)-NH2::Dynorphin A analogues::H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-NH2::HTyr-Gly-Gly-Phe-Leu-Arg-Arg-lle-Arg-Pro-LysNH2::Linear Dyn A-(1-11)NH2::Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-D-Lys-NH2::Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln-NH2 Mu-type opioid receptor Cavia cutleri 0.653 ChEMBL 10.1021/jm0101186 10.7270/Q28K79SN 11543672 Lu, Y; Nguyen, TM; Weltrowska, G; Berezowska, I; Lemieux, C; Chung, NN; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010704 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010704&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10677974 103923450 CHEMBL216640 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50802362 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2[C@@H]4Oc6c7c(C[C@H]8N(CC9CC9)CC[C@@]47[C@@]8(O)Cc2c1C[C@@]35O)ccc6O InChI=1S/C40H43N3O6/c44-25-7-5-21-13-27-39(46)15-23-24-16-40(47)28-14-22-6-8-26(45)34-30(22)38(40,10-12-43(28)18-20-3-4-20)36(49-34)32(24)41-31(23)35-37(39,29(21)33(25)48-35)9-11-42(27)17-19-1-2-19/h5-8,19-20,27-28,35-36,41,44-47H,1-4,9-18H2/t27-,28-,35+,36+,37+,38+,39-,40-/m1/s1 APSUXPSYBJVPPS-YAUKWVCOSA-N 82551 C18130::CAS_105618-26-6::NOR-BNI (HCI)2::NORBNI Mu-type opioid receptor Cavia cutleri 28.4 ChEMBL 10.1021/jm0101186 10.7270/Q28K79SN 11543672 Lu, Y; Nguyen, TM; Weltrowska, G; Berezowska, I; Lemieux, C; Chung, NN; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82551&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5480230 136350521 C18130 ZINC03995590 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50802366 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NOC(=O)[C@@H](C)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C76H120N22O15/c1-9-43(4)62(71(110)93-56(24-17-33-87-76(83)84)72(111)98-34-18-25-60(98)70(109)90-53(63(78)102)21-13-14-30-77)96-67(106)55(23-16-32-86-75(81)82)91-66(105)54(22-15-31-85-74(79)80)92-68(107)57(35-42(2)3)95-69(108)58(39-48-19-11-10-12-20-48)94-64(103)47(8)89-61(101)41-88-65(104)59(40-49-26-28-50(99)29-27-49)97-113-73(112)46(7)38-52-44(5)36-51(100)37-45(52)6/h10-12,19-20,26-29,36-37,42-43,46-47,53-60,62,97,99-100H,9,13-18,21-25,30-35,38-41,77H2,1-8H3,(H2,78,102)(H,88,104)(H,89,101)(H,90,109)(H,91,105)(H,92,107)(H,93,110)(H,94,103)(H,95,108)(H,96,106)(H4,79,80,85)(H4,81,82,86)(H4,83,84,87)/t43-,46-,47-,53-,54-,55-,56-,57-,58-,59-,60-,62-/m0/s1 CNRAWPBHIWWVHH-URLZOTGNSA-N 50103973 CHEMBL407124::[(2S)-Mdp1,D-Ala3]Dyn A(1-11)-NH2 Mu-type opioid receptor Cavia cutleri 167 ChEMBL 10.1021/jm0101186 10.7270/Q28K79SN 11543672 Lu, Y; Nguyen, TM; Weltrowska, G; Berezowska, I; Lemieux, C; Chung, NN; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103973 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103973&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44334304 103999959 CHEMBL407124 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50832347 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@@]3(CCC4=O)OCC=C)ccc5O InChI=1S/C20H23NO4/c1-3-10-24-20-7-6-14(23)18-19(20)8-9-21(2)15(20)11-12-4-5-13(22)17(25-18)16(12)19/h3-5,15,18,22H,1,6-11H2,2H3/t15?,18-,19-,20+/m0/s1 YTYSMQUWSIEJSV-VCPZZJCDSA-N 50166213 17-allyloxy-10-hydroxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one Mu-type opioid receptor Cavia cutleri 17.6 ChEMBL 10.1021/jm040894o 10.7270/Q2X92C3R 15857143 Lattanzi, R; Spetea, M; Schullner, F; Rief, SB; Krassnig, R; Negri, L; Schmidhammer, H Sapienza University of Rome http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50166213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50166213&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44400220 104051705 ZINC13643633 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50832348 CO[C@]12CCC(=O)[C@]3(C)Oc4c5c(CC1N(C)CC[C@@]235)ccc4O InChI=1S/C19H23NO4/c1-17-14(22)6-7-19(23-3)13-10-11-4-5-12(21)16(24-17)15(11)18(17,19)8-9-20(13)2/h4-5,13,21H,6-10H2,1-3H3/t13?,17-,18-,19+/m0/s1 DENICFHULARDRG-IKJNLRRPSA-N 50127165 10-hydroxy-17-methoxy-4,13-dimethyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::10-hydroxy-17-methoxy-4,13-dimethyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-trien-14-one Mu-type opioid receptor Cavia cutleri 6.1 ChEMBL 10.1021/jm040894o 10.7270/Q2X92C3R 15857143 Lattanzi, R; Spetea, M; Schullner, F; Rief, SB; Krassnig, R; Negri, L; Schmidhammer, H Sapienza University of Rome http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127165 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127165&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44294692 104019094 ZINC03982101 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50832350 CO[C@]12CCC(=O)[C@@H]3Oc4c5c(C[C@H]1N(C)CC[C@@]235)ccc4O InChI=1S/C18H21NO4/c1-19-8-7-17-14-10-3-4-11(20)15(14)23-16(17)12(21)5-6-18(17,22-2)13(19)9-10/h3-4,13,16,20H,5-9H2,1-2H3/t13-,16+,17+,18-/m1/s1 FCIDDJPMOSRHJG-XFKAJCMBSA-N 50326662 10-hydroxy-17-methoxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::CHEMBL607405 Mu-type opioid receptor Cavia cutleri 2 ChEMBL 10.1021/jm040894o 10.7270/Q2X92C3R 15857143 Lattanzi, R; Spetea, M; Schullner, F; Rief, SB; Krassnig, R; Negri, L; Schmidhammer, H Sapienza University of Rome http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326662 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326662&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 13559325 123105777 CHEMBL607405 ZINC13643648 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50832352 CN1CC[C@]23c4c5O[C@@]2(C)C(=O)CC[C@@]3(OCc2ccccc2)C1Cc4ccc5O InChI=1S/C25H27NO4/c1-23-20(28)10-11-25(29-15-16-6-4-3-5-7-16)19-14-17-8-9-18(27)22(30-23)21(17)24(23,25)12-13-26(19)2/h3-9,19,27H,10-15H2,1-2H3/t19?,23-,24-,25+/m0/s1 BROLKJHQMMXCRO-DYZJZLFBSA-N 50166215 17-benzyloxy-10-hydroxy-4,13-dimethyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one Mu-type opioid receptor Cavia cutleri 0.5 ChEMBL 10.1021/jm040894o 10.7270/Q2X92C3R 15857143 Lattanzi, R; Spetea, M; Schullner, F; Rief, SB; Krassnig, R; Negri, L; Schmidhammer, H Sapienza University of Rome http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50166215 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50166215&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44400397 104051707 ZINC13643636 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50832355 CCO[C@]12CCC(=O)[C@]3(C)Oc4c5c(CC1N(CCc1ccccc1)CC[C@@]235)ccc4O InChI=1S/C27H31NO4/c1-3-31-27-13-11-22(30)25(2)26(27)14-16-28(15-12-18-7-5-4-6-8-18)21(27)17-19-9-10-20(29)24(32-25)23(19)26/h4-10,21,29H,3,11-17H2,1-2H3/t21?,25-,26-,27+/m0/s1 YNNFSTLAUJEYHI-SSNGLDLMSA-N 50166212 17-ethoxy-10-hydroxy-13-methyl-4-phenethyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one Mu-type opioid receptor Cavia cutleri 1.9 ChEMBL 10.1021/jm040894o 10.7270/Q2X92C3R 15857143 Lattanzi, R; Spetea, M; Schullner, F; Rief, SB; Krassnig, R; Negri, L; Schmidhammer, H Sapienza University of Rome http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50166212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50166212&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44400280 104051704 ZINC13643645 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50832358 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@@]3(CCC4=O)OCc1cccc2ccccc12)ccc5O InChI=1S/C28H27NO4/c1-29-14-13-27-24-18-9-10-21(30)25(24)33-26(27)22(31)11-12-28(27,23(29)15-18)32-16-19-7-4-6-17-5-2-3-8-20(17)19/h2-10,23,26,30H,11-16H2,1H3/t23?,26-,27-,28+/m0/s1 QCOHCCAYFMDVKX-GDOYDIOZSA-N 50166214 10-hydroxy-4-methyl-17-(1-naphthylmethoxy)-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one Mu-type opioid receptor Cavia cutleri 0.9 ChEMBL 10.1021/jm040894o 10.7270/Q2X92C3R 15857143 Lattanzi, R; Spetea, M; Schullner, F; Rief, SB; Krassnig, R; Negri, L; Schmidhammer, H Sapienza University of Rome http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50166214 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50166214&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44400337 104051706 ZINC13643639 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50832359 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@@]3(CCC4=O)OCc1ccccc1)ccc5O InChI=1S/C24H25NO4/c1-25-12-11-23-20-16-7-8-17(26)21(20)29-22(23)18(27)9-10-24(23,19(25)13-16)28-14-15-5-3-2-4-6-15/h2-8,19,22,26H,9-14H2,1H3/t19?,22-,23-,24+/m0/s1 JIZIIPYPMGBADK-UOUIHQBBSA-N 50166216 17-benzyloxy-10-hydroxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one Mu-type opioid receptor Cavia cutleri 0.9 ChEMBL 10.1021/jm040894o 10.7270/Q2X92C3R 15857143 Lattanzi, R; Spetea, M; Schullner, F; Rief, SB; Krassnig, R; Negri, L; Schmidhammer, H Sapienza University of Rome http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50166216 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50166216&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44400177 104051708 ZINC06745060 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50832372 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 311 ChEMBL 10.1021/jm040894o 10.7270/Q2X92C3R 15857143 Lattanzi, R; Spetea, M; Schullner, F; Rief, SB; Krassnig, R; Negri, L; Schmidhammer, H Sapienza University of Rome http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50832376 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@@]3(CCC4=O)OCc1c(Cl)cccc1Cl)ccc5O InChI=1S/C24H23Cl2NO4/c1-27-10-9-23-20-13-5-6-17(28)21(20)31-22(23)18(29)7-8-24(23,19(27)11-13)30-12-14-15(25)3-2-4-16(14)26/h2-6,19,22,28H,7-12H2,1H3/t19?,22-,23-,24+/m0/s1 WOAFLDTXSHAUKV-UOUIHQBBSA-N 50166217 17-(2,6-dichlorobenzyloxy)-10-hydroxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one Mu-type opioid receptor Cavia cutleri 1000 ChEMBL 10.1021/jm040894o 10.7270/Q2X92C3R 15857143 Lattanzi, R; Spetea, M; Schullner, F; Rief, SB; Krassnig, R; Negri, L; Schmidhammer, H Sapienza University of Rome http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50166217 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50166217&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44400423 104051709 ZINC13643642 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50819929 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@@H]3Cc1cc(cnc41)-c1ccc(Cl)cc1)ccc5O InChI=1S/C26H23ClN2O2/c1-29-9-8-26-19-11-16-10-17(14-2-5-18(27)6-3-14)13-28-23(16)25(26)31-24-21(30)7-4-15(22(24)26)12-20(19)29/h2-7,10,13,19-20,25,30H,8-9,11-12H2,1H3/t19-,20?,25-,26-/m0/s1 PFCJBVJVJPUGBT-FMMCSPAXSA-N 50140901 6-(4-chlorophenyl)-19-methyl-(2R,10R)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaen-13-ol Mu-type opioid receptor Cavia cutleri 177 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140901 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140901&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44280396 104030437 ZINC03943034 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50819931 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@]3(O)Cc1cccnc41)ccc5O InChI=1S/C20H20N2O3/c1-22-8-6-19-15-11-4-5-13(23)17(15)25-18(19)16-12(3-2-7-21-16)10-20(19,24)14(22)9-11/h2-5,7,14,18,23-24H,6,8-10H2,1H3/t14?,18-,19-,20+/m0/s1 BMECSLWZPCVUJH-QDHLSEFBSA-N 50140899 19-methyl-(2S,10R)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaene-2,13-diol Mu-type opioid receptor Cavia cutleri 523 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140899 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140899&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44279664 104030435 ZINC13559694 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50819939 CN([C@@H](Cc1ccccc1)C(=O)N1CCC[C@@H]1C(N)=O)C(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C29H37N5O5/c1-32(25(18-19-7-3-2-4-8-19)29(39)33-15-5-9-23(33)26(31)36)28(38)24-10-6-16-34(24)27(37)22(30)17-20-11-13-21(35)14-12-20/h2-4,7-8,11-14,22-25,35H,5-6,9-10,15-18,30H2,1H3,(H2,31,36)/t22-,23+,24-,25-/m0/s1 JAKBYSTWCHUQOK-NDBXHCKUSA-N 50140906 1-[2-[1-[2-amino-3-(4-hydroxyphenyl)-(2S)-propanoyl]-(5S)-dihydro-1H-5-pyrrolyl(methyl)carboxamido]-3-phenyl-(2S)-propanoyl]-(5R)-dihydro-1H-5-pyrrolecarboxamide::CHEMBL283287 Mu-type opioid receptor Cavia cutleri 59 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140906 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140906&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 115335 104030442 CHEMBL283287 1671 ZINC14953444 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50819950 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@@H]3Cc1cccnc41)ccc5O InChI=1S/C20H20N2O2/c1-22-8-6-20-13-9-12-3-2-7-21-17(12)19(20)24-18-15(23)5-4-11(16(18)20)10-14(13)22/h2-5,7,13-14,19,23H,6,8-10H2,1H3/t13-,14?,19-,20-/m0/s1 AYGOLJCOJMGZAR-GEQWREAYSA-N 50140910 19-methyl-(2R,10R)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaen-13-ol Mu-type opioid receptor Cavia cutleri 68 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140910 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140910&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44280395 104030446 ZINC13559698 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50819953 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@@H]3Cc1cc(cnc41)-c1ccccc1)ccc5O InChI=1S/C26H24N2O2/c1-28-10-9-26-19-12-17-11-18(15-5-3-2-4-6-15)14-27-23(17)25(26)30-24-21(29)8-7-16(22(24)26)13-20(19)28/h2-8,11,14,19-20,25,29H,9-10,12-13H2,1H3/t19-,20?,25-,26-/m0/s1 GRNLHIJZMLLROK-FMMCSPAXSA-N 50140905 19-methyl-6-phenyl-(2R,10R)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaen-13-ol Mu-type opioid receptor Cavia cutleri 99 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140905 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140905&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44279589 104030441 ZINC13559699 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50820001 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45C(Oc1c24)c1ncc(cc1C[C@@]35O)-c1ccc(Cl)cc1 InChI=1S/C29H27ClN2O3/c30-21-6-3-17(4-7-21)20-11-19-13-29(34)23-12-18-5-8-22(33)26-24(18)28(29,27(35-26)25(19)31-14-20)9-10-32(23)15-16-1-2-16/h3-8,11,14,16,23,27,33-34H,1-2,9-10,12-13,15H2/t23-,27?,28+,29-/m1/s1 WRVDUHKCIPYGNZ-VKZBBXDISA-N 50080467 5'-(Chlorophenyl)-17-(cyclopropylmethyl) -6,7-didehydro-3,14-dihydroxy-4,5alpha-epoxypyrido-[2',3':6,7]morphinan::CHEMBL325600 Mu-type opioid receptor Cavia cutleri 163 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080467&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9913318 103980624 CHEMBL325600 ZINC27109331 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50820011 Oc1ccc2CC3[C@@H]4Cc5cc(cnc5[C@@H]5Oc1c2[C@]45CCN3CC1CC1)-c1ccc(Cl)cc1 InChI=1S/C29H27ClN2O2/c30-21-6-3-17(4-7-21)20-11-19-12-22-23-13-18-5-8-24(33)27-25(18)29(22,28(34-27)26(19)31-14-20)9-10-32(23)15-16-1-2-16/h3-8,11,14,16,22-23,28,33H,1-2,9-10,12-13,15H2/t22-,23?,28-,29-/m0/s1 GSOFQIRSCHLMHR-OPECHTPQSA-N 50140913 6-(4-chlorophenyl)-19-cyclopropylmethyl-(2R,10R)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaen-13-ol Mu-type opioid receptor Cavia cutleri 109 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140913 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140913&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44279825 104030449 ZINC13559703 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50820025 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@@H]3Cc1cc(cnc41)-c1ccc(Br)cc1)ccc5O InChI=1S/C26H23BrN2O2/c1-29-9-8-26-19-11-16-10-17(14-2-5-18(27)6-3-14)13-28-23(16)25(26)31-24-21(30)7-4-15(22(24)26)12-20(19)29/h2-7,10,13,19-20,25,30H,8-9,11-12H2,1H3/t19-,20?,25-,26-/m0/s1 QLUHBBPMGPGYMW-FMMCSPAXSA-N 50140898 6-(4-bromophenyl)-19-methyl-(2R,10R)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaen-13-ol Mu-type opioid receptor Cavia cutleri 666 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140898 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140898&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44279588 104030434 ZINC13559700 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50820035 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@@H]3Cc1cc(cnc41)-c1ccc(Cl)c(Cl)c1)ccc5O InChI=1S/C26H22Cl2N2O2/c1-30-7-6-26-17-9-15-8-16(13-2-4-18(27)19(28)10-13)12-29-23(15)25(26)32-24-21(31)5-3-14(22(24)26)11-20(17)30/h2-5,8,10,12,17,20,25,31H,6-7,9,11H2,1H3/t17-,20?,25-,26-/m0/s1 UYVJZQXUZSFCBU-MTJLISISSA-N 50140909 6-(3,4-dichlorophenyl)-19-methyl-(2R,10R)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaen-13-ol Mu-type opioid receptor Cavia cutleri 447 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140909 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140909&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44279826 104030445 ZINC13559701 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50820038 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@@H]3Cc1cc(cnc41)-c1ccc(Cl)cc1Cl)ccc5O InChI=1S/C26H22Cl2N2O2/c1-30-7-6-26-18-9-14-8-15(17-4-3-16(27)11-19(17)28)12-29-23(14)25(26)32-24-21(31)5-2-13(22(24)26)10-20(18)30/h2-5,8,11-12,18,20,25,31H,6-7,9-10H2,1H3/t18-,20?,25-,26-/m0/s1 YVSJJZSJQLXGBW-JIXRRBMOSA-N 50140900 6-(2,4-dichlorophenyl)-19-methyl-(2R,10R)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaen-13-ol Mu-type opioid receptor Cavia cutleri 724 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140900 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140900&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44279841 104030436 ZINC13559702 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50820049 CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@]3(O)Cc1cc(cnc41)-c1ccccc1)ccc5O InChI=1S/C26H24N2O3/c1-28-10-9-25-21-16-7-8-19(29)23(21)31-24(25)22-17(13-26(25,30)20(28)12-16)11-18(14-27-22)15-5-3-2-4-6-15/h2-8,11,14,20,24,29-30H,9-10,12-13H2,1H3/t20?,24-,25-,26+/m0/s1 MVNIBXTXVYCLEI-OOGIKFLQSA-N 50140903 19-methyl-6-phenyl-(2S,10R)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaene-2,13-diol Mu-type opioid receptor Cavia cutleri 211 ChEMBL 10.1021/jm030311v 10.7270/Q2639QGW 14998329 Ananthan, S; Khare, NK; Saini, SK; Seitz, LE; Bartlett, JL; Davis, P; Dersch, CM; Porreca, F; Rothman, RB; Bilsky, EJ Southern Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140903 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140903&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44279662 104030439 ZINC13559695 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50836902 CCCC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NN[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@H](C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)C(=O)N[C@H](Cc1cn(C(=O)OC(C)(C)C)c2ccccc12)C(O)=O InChI=1S/C58H71N9O15/c1-6-7-21-41(52(74)64-46(56(79)80)30-38-33-67(57(81)82-58(3,4)5)47-22-15-14-20-40(38)47)61-53(75)42(31-49(70)71)62-54(76)44(28-36-18-12-9-13-19-36)66-65-43(27-35-16-10-8-11-17-35)51(73)59-32-48(69)60-34(2)50(72)63-45(55(77)78)29-37-23-25-39(68)26-24-37/h8-20,22-26,33-34,41-46,65-66,68H,6-7,21,27-32H2,1-5H3,(H,59,73)(H,60,69)(H,61,75)(H,62,76)(H,63,72)(H,64,74)(H,70,71)(H,77,78)(H,79,80)/t34-,41+,42+,43+,44+,45+,46-/m1/s1 IYNMVGGOTRCWGJ-KSEFKAEUSA-N 50183551 CHEMBL413644::H-Tyr-D-Ala-Gly-Phe-NH-NH-Phe-Asp-Nle-D-Trp-Boc Mu-type opioid receptor Cavia cutleri 460 ChEMBL 10.1021/jm050851n 10.7270/Q2FT8MVM 16509592 Lee, YS; Agnes, RS; Badghisi, H; Davis, P; Ma, SW; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183551&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44408590 104068024 CHEMBL413644 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50836919 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C46H56N10O10/c1-27(51-43(63)35(47)21-31-13-17-33(57)18-14-31)41(61)49-25-39(59)53-37(23-29-9-5-3-6-10-29)45(65)55-56-46(66)38(24-30-11-7-4-8-12-30)54-40(60)26-50-42(62)28(2)52-44(64)36(48)22-32-15-19-34(58)20-16-32/h3-20,27-28,35-38,57-58H,21-26,47-48H2,1-2H3,(H,49,61)(H,50,62)(H,51,63)(H,52,64)(H,53,59)(H,54,60)(H,55,65)(H,56,66)/t27-,28-,35+,36+,37+,38+/m1/s1 DESSEGDLRYOPTJ-VRANXALZSA-N 21014 (2S)-2-amino-N-[(1R)-1-[({[(1S)-1-{N'-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanoyl]hydrazinecarbonyl}-2-phenylethyl]carbamoyl}methyl)carbamoyl]ethyl]-3-(4-hydroxyphenyl)propanamide::(Tyr-Ala-Gly-Phe-NH2)2::Biphalin::CHEMBL200199::bis(Tyr-Ala-Gly-PheNH2)hydrazide::enkephalin dimer Mu-type opioid receptor Cavia cutleri 8.8 ChEMBL 10.1021/jm050851n 10.7270/Q2FT8MVM 16509592 Lee, YS; Agnes, RS; Badghisi, H; Davis, P; Ma, SW; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21014&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5487663 49689087 CHEMBL200199 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50836922 CCCC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NN[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@H](C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)C(=O)N[C@@H](Cc1cn(C(C)=O)c2ccccc12)C(O)=O InChI=1S/C55H65N9O14/c1-4-5-19-40(51(72)61-45(55(77)78)28-37-31-64(33(3)65)46-20-13-12-18-39(37)46)58-52(73)41(29-48(68)69)59-53(74)43(26-35-16-10-7-11-17-35)63-62-42(25-34-14-8-6-9-15-34)50(71)56-30-47(67)57-32(2)49(70)60-44(54(75)76)27-36-21-23-38(66)24-22-36/h6-18,20-24,31-32,40-45,62-63,66H,4-5,19,25-30H2,1-3H3,(H,56,71)(H,57,67)(H,58,73)(H,59,74)(H,60,70)(H,61,72)(H,68,69)(H,75,76)(H,77,78)/t32-,40+,41+,42+,43+,44+,45+/m1/s1 RBNPCZIQGBMFDV-FPWNPRTMSA-N 50183557 CHEMBL442483::H-Tyr-D-Ala-Gly-Phe-NH-NH-Phe-Asp-Nle-Trp-Ac Mu-type opioid receptor Cavia cutleri 28 ChEMBL 10.1021/jm050851n 10.7270/Q2FT8MVM 16509592 Lee, YS; Agnes, RS; Badghisi, H; Davis, P; Ma, SW; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183557&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44408525 104068030 CHEMBL442483 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50836938 CCCC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NN[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@H](C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)C(=O)N[C@@H](Cc1cn(C(=O)OC(C)(C)C)c2ccccc12)C(O)=O InChI=1S/C58H71N9O15/c1-6-7-21-41(52(74)64-46(56(79)80)30-38-33-67(57(81)82-58(3,4)5)47-22-15-14-20-40(38)47)61-53(75)42(31-49(70)71)62-54(76)44(28-36-18-12-9-13-19-36)66-65-43(27-35-16-10-8-11-17-35)51(73)59-32-48(69)60-34(2)50(72)63-45(55(77)78)29-37-23-25-39(68)26-24-37/h8-20,22-26,33-34,41-46,65-66,68H,6-7,21,27-32H2,1-5H3,(H,59,73)(H,60,69)(H,61,75)(H,62,76)(H,63,72)(H,64,74)(H,70,71)(H,77,78)(H,79,80)/t34-,41+,42+,43+,44+,45+,46+/m1/s1 IYNMVGGOTRCWGJ-CHAGIDMDSA-N 50183558 CHEMBL405192::H-Tyr-D-Ala-Gly-Phe-NH-NH-Phe-Asp-Nle-Trp-Boc Mu-type opioid receptor Cavia cutleri 55 ChEMBL 10.1021/jm050851n 10.7270/Q2FT8MVM 16509592 Lee, YS; Agnes, RS; Badghisi, H; Davis, P; Ma, SW; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183558&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44408524 104068031 CHEMBL405192 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50836949 CCCC[C@H](N(C(=O)Nc1ccccc1Cl)C(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)N(C)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@H](C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)C(=O)N[C@@H](Cc1cn(C(C)=O)c2ccccc12)C(O)=O InChI=1S/C63H71ClN10O15/c1-5-6-24-52(58(82)69-50(62(87)88)33-42-36-73(38(3)75)51-25-16-13-21-44(42)51)74(63(89)70-46-23-15-14-22-45(46)64)60(84)48(34-55(78)79)67-59(83)53(32-40-19-11-8-12-20-40)72(4)71-47(30-39-17-9-7-10-18-39)57(81)65-35-54(77)66-37(2)56(80)68-49(61(85)86)31-41-26-28-43(76)29-27-41/h7-23,25-29,36-37,47-50,52-53,71,76H,5-6,24,30-35H2,1-4H3,(H,65,81)(H,66,77)(H,67,83)(H,68,80)(H,69,82)(H,70,89)(H,78,79)(H,85,86)(H,87,88)/t37-,47+,48+,49+,50+,52+,53+/m1/s1 ZICGXQSIIFWORG-XXDIXCCXSA-N 50183552 CHEMBL412331::H-Tyr-D-Ala-Gly-Phe-NH-NH-(NMe)Phe-Asp-Lys(Cpac)-Trp-Ac Mu-type opioid receptor Cavia cutleri 200 ChEMBL 10.1021/jm050851n 10.7270/Q2FT8MVM 16509592 Lee, YS; Agnes, RS; Badghisi, H; Davis, P; Ma, SW; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183552 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183552&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44408411 104068025 CHEMBL412331 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50836952 CCCC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NN[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@H](C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)C(=O)N[C@H](Cc1cn(C(=O)OC23CC4CC(CC(C4)C2)C3)c2ccccc12)C(O)=O InChI=1S/C64H77N9O15/c1-3-4-18-47(58(80)70-52(62(85)86)30-44-36-73(53-19-12-11-17-46(44)53)63(87)88-64-32-41-24-42(33-64)26-43(25-41)34-64)67-59(81)48(31-55(76)77)68-60(82)50(28-39-15-9-6-10-16-39)72-71-49(27-38-13-7-5-8-14-38)57(79)65-35-54(75)66-37(2)56(78)69-51(61(83)84)29-40-20-22-45(74)23-21-40/h5-17,19-23,36-37,41-43,47-52,71-72,74H,3-4,18,24-35H2,1-2H3,(H,65,79)(H,66,75)(H,67,81)(H,68,82)(H,69,78)(H,70,80)(H,76,77)(H,83,84)(H,85,86)/t37-,41?,42?,43?,47+,48+,49+,50+,51+,52-,64?/m1/s1 VVKBKPBAKDXLOT-UEJOTSENSA-N 50183555 CHEMBL408832::H-Tyr-D-Ala-Gly-Phe-NH-NH-Phe-Asp-Nle-D-Trp-1-Adoc Mu-type opioid receptor Cavia cutleri 640 ChEMBL 10.1021/jm050851n 10.7270/Q2FT8MVM 16509592 Lee, YS; Agnes, RS; Badghisi, H; Davis, P; Ma, SW; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183555 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183555&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44408632 104068028 CHEMBL408832 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50836954 CCCC[C@H](N(C)C(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C55H66N10O13/c1-3-4-19-45(54(77)64-43(29-48(70)71)53(76)61-40(49(57)72)24-32-13-7-5-8-14-32)65(2)55(78)44(27-35-30-58-39-18-12-11-17-37(35)39)60-46(67)31-59-51(74)41(25-33-15-9-6-10-16-33)63-52(75)42(26-34-20-22-36(66)23-21-34)62-50(73)38(56)28-47(68)69/h5-18,20-23,30,38,40-45,58,66H,3-4,19,24-29,31,56H2,1-2H3,(H2,57,72)(H,59,74)(H,60,67)(H,61,76)(H,62,73)(H,63,75)(H,64,77)(H,68,69)(H,70,71)/t38-,40-,41+,42-,43-,44-,45-/m0/s1 IJHCWGDIGBABKC-GDHOWUIUSA-N 21146 (3S)-3-[(2S)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-[(3S)-3-amino-3-formamidopropanoic acid]-3-(4-hydroxyphenyl)propanamido]-3-phenylpropanamido]acetamido}-3-(1H-indol-3-yl)-N-methylpropanamido]hexanamido]-3-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}propanoic acid::Asp-Tyr-D-Phe-Gly-Trp-NMeNle-Asp-Phe-NH2::CHEMBL407057::SNF-9007 Mu-type opioid receptor Cavia cutleri 220 ChEMBL 10.1021/jm050851n 10.7270/Q2FT8MVM 16509592 Lee, YS; Agnes, RS; Badghisi, H; Davis, P; Ma, SW; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21146 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21146&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9898185 49689219 CHEMBL407057 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50836958 CCCC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NN[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@H](C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(O)=O InChI=1S/C53H63N9O13/c1-3-4-18-39(49(69)60-44(53(74)75)27-35-29-54-38-19-12-11-17-37(35)38)57-50(70)40(28-46(65)66)58-51(71)42(25-33-15-9-6-10-16-33)62-61-41(24-32-13-7-5-8-14-32)48(68)55-30-45(64)56-31(2)47(67)59-43(52(72)73)26-34-20-22-36(63)23-21-34/h5-17,19-23,29,31,39-44,54,61-63H,3-4,18,24-28,30H2,1-2H3,(H,55,68)(H,56,64)(H,57,70)(H,58,71)(H,59,67)(H,60,69)(H,65,66)(H,72,73)(H,74,75)/t31-,39+,40+,41+,42+,43+,44-/m1/s1 LHFDBKUCTFELLO-WMRIFXDUSA-N 50183553 CHEMBL375412::H-Tyr-D-Ala-Gly-Phe-NH-NH-Phe-Asp-Nle-D-Trp-H Mu-type opioid receptor Cavia cutleri 81 ChEMBL 10.1021/jm050851n 10.7270/Q2FT8MVM 16509592 Lee, YS; Agnes, RS; Badghisi, H; Davis, P; Ma, SW; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183553 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183553&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44408484 104068026 CHEMBL375412 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50836961 CCCC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NN[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@H](C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)C(=O)N[C@H](Cc1cn(C(=O)OC2C3CC4CC(C3)CC2C4)c2ccccc12)C(O)=O InChI=1S/C64H77N9O15/c1-3-4-18-47(59(80)70-52(63(85)86)32-44-35-73(53-19-12-11-17-46(44)53)64(87)88-56-42-25-40-24-41(27-42)28-43(56)26-40)67-60(81)48(33-55(76)77)68-61(82)50(30-38-15-9-6-10-16-38)72-71-49(29-37-13-7-5-8-14-37)58(79)65-34-54(75)66-36(2)57(78)69-51(62(83)84)31-39-20-22-45(74)23-21-39/h5-17,19-23,35-36,40-43,47-52,56,71-72,74H,3-4,18,24-34H2,1-2H3,(H,65,79)(H,66,75)(H,67,81)(H,68,82)(H,69,78)(H,70,80)(H,76,77)(H,83,84)(H,85,86)/t36-,40?,41?,42?,43?,47+,48+,49+,50+,51+,52-,56?/m1/s1 VEGZKBKISJJLJC-FCVZMFCYSA-N 50183554 CHEMBL438739::H-Tyr-D-Ala-Gly-Phe-NH-NH-Phe-Asp-Nle-D-Trp-2-Adoc Mu-type opioid receptor Cavia cutleri 1200 ChEMBL 10.1021/jm050851n 10.7270/Q2FT8MVM 16509592 Lee, YS; Agnes, RS; Badghisi, H; Davis, P; Ma, SW; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183554 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183554&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44408483 104068027 CHEMBL438739 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50836968 CCCC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)N(C)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@H](C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)C(=O)N[C@@H](Cc1cn(C(C)=O)c2ccccc12)C(O)=O InChI=1S/C56H67N9O14/c1-5-6-20-41(52(73)62-45(56(78)79)29-38-32-65(34(3)66)46-21-14-13-19-40(38)46)59-53(74)42(30-49(69)70)60-54(75)47(28-36-17-11-8-12-18-36)64(4)63-43(26-35-15-9-7-10-16-35)51(72)57-31-48(68)58-33(2)50(71)61-44(55(76)77)27-37-22-24-39(67)25-23-37/h7-19,21-25,32-33,41-45,47,63,67H,5-6,20,26-31H2,1-4H3,(H,57,72)(H,58,68)(H,59,74)(H,60,75)(H,61,71)(H,62,73)(H,69,70)(H,76,77)(H,78,79)/t33-,41+,42+,43+,44+,45+,47+/m1/s1 DZRXMQMULMXHKQ-GDYSDZBQSA-N 50183556 CHEMBL408889::H-Tyr-D-Ala-Gly-Phe-NH-NH-(NMe)Phe-Asp-Nle-Trp-Ac Mu-type opioid receptor Cavia cutleri 62 ChEMBL 10.1021/jm050851n 10.7270/Q2FT8MVM 16509592 Lee, YS; Agnes, RS; Badghisi, H; Davis, P; Ma, SW; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183556 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183556&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44408417 104068029 CHEMBL408889 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50823630 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C46H56N10O10/c1-27(51-43(63)35(47)21-31-13-17-33(57)18-14-31)41(61)49-25-39(59)53-37(23-29-9-5-3-6-10-29)45(65)55-56-46(66)38(24-30-11-7-4-8-12-30)54-40(60)26-50-42(62)28(2)52-44(64)36(48)22-32-15-19-34(58)20-16-32/h3-20,27-28,35-38,57-58H,21-26,47-48H2,1-2H3,(H,49,61)(H,50,62)(H,51,63)(H,52,64)(H,53,59)(H,54,60)(H,55,65)(H,56,66)/t27-,28-,35+,36+,37+,38+/m1/s1 DESSEGDLRYOPTJ-VRANXALZSA-N 21014 (2S)-2-amino-N-[(1R)-1-[({[(1S)-1-{N'-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanoyl]hydrazinecarbonyl}-2-phenylethyl]carbamoyl}methyl)carbamoyl]ethyl]-3-(4-hydroxyphenyl)propanamide::(Tyr-Ala-Gly-Phe-NH2)2::Biphalin::CHEMBL200199::bis(Tyr-Ala-Gly-PheNH2)hydrazide::enkephalin dimer Mu-type opioid receptor Cavia cutleri 8.8 ChEMBL 10.1016/j.bmcl.2005.03.067 10.7270/Q22Z169S 15863299 Mollica, A; Davis, P; Ma, SW; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21014&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5487663 49689087 CHEMBL200199 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50823631 C[C@H](N[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@H](Cc1ccccc1)C(=O)N1CCN(CC1)C(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C49H62N10O9/c1-31(54-42(51)28-36-15-19-38(61)20-16-36)45(64)52-29-43(62)56-40(26-33-9-5-3-6-10-33)48(67)58-21-23-59(24-22-58)49(68)41(27-34-11-7-4-8-12-34)57-44(63)30-53-46(65)32(2)55-47(66)39(50)25-35-13-17-37(60)18-14-35/h3-20,31-32,39-42,54,60-61H,21-30,50-51H2,1-2H3,(H,52,64)(H,53,65)(H,55,66)(H,56,62)(H,57,63)/t31-,32+,39-,40+,41-,42+/m0/s1 NYJNBEAFFCJSGV-FKEYJJNNSA-N 50166354 2-Amino-N-(1-{[(2-{(S)-4-[(R)-2-(2-{(S)-2-[1-amino-2-((R)-4-hydroxy-phenyl)-ethylamino]-propionylamino}-acetylamino)-3-phenyl-propionyl]-piperazin-1-yl}-1-benzyl-2-oxo-ethylcarbamoyl)-methyl]-carbamoyl}-ethyl)-3-((R)-4-hydroxy-phenyl)-propionamide; ditrifluoroacetic acid::CHEMBL414251 Mu-type opioid receptor Cavia cutleri 2.5 ChEMBL 10.1016/j.bmcl.2005.03.067 10.7270/Q22Z169S 15863299 Mollica, A; Davis, P; Ma, SW; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50166354 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50166354&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44401647 104051835 CHEMBL414251 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50823634 C[C@H](N[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@H](Cc1ccccc1)C(=O)Nc1ccc(NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc2ccc(O)cc2)cc1 InChI=1S/C51H60N10O9/c1-31(56-44(53)28-36-15-23-40(63)24-16-36)47(66)54-29-45(64)60-42(26-33-9-5-3-6-10-33)50(69)58-37-17-19-38(20-18-37)59-51(70)43(27-34-11-7-4-8-12-34)61-46(65)30-55-48(67)32(2)57-49(68)41(52)25-35-13-21-39(62)22-14-35/h3-24,31-32,41-44,56,62-63H,25-30,52-53H2,1-2H3,(H,54,66)(H,55,67)(H,57,68)(H,58,69)(H,59,70)(H,60,64)(H,61,65)/t31-,32+,41-,42+,43-,44+/m0/s1 NUELKGKENOFLEP-FESPOEILSA-N 50166351 2-Amino-N-((S)-1-{[(1-{(S)-4-[(R)-2-(2-{2-[1-amino-2-((R)-4-hydroxy-phenyl)-ethylamino]-propionylamino}-acetylamino)-3-(S)-phenyl-propionylamino]-phenylcarbamoyl}-2-phenyl-ethylcarbamoyl)-methyl]-carbamoyl}-ethyl)-3-(4-hydroxy-phenyl)-propionamide; ditrifluoroacetic acid::CHEMBL262490 Mu-type opioid receptor Cavia cutleri 40 ChEMBL 10.1016/j.bmcl.2005.03.067 10.7270/Q22Z169S 15863299 Mollica, A; Davis, P; Ma, SW; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50166351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50166351&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44401645 104051832 CHEMBL262490 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50823638 C[C@H](N[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@H](Cc1ccccc1)C(=O)Nc1ccccc1NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C51H60N10O9/c1-31(56-44(53)28-36-19-23-38(63)24-20-36)47(66)54-29-45(64)58-42(26-33-11-5-3-6-12-33)50(69)60-40-15-9-10-16-41(40)61-51(70)43(27-34-13-7-4-8-14-34)59-46(65)30-55-48(67)32(2)57-49(68)39(52)25-35-17-21-37(62)22-18-35/h3-24,31-32,39,42-44,56,62-63H,25-30,52-53H2,1-2H3,(H,54,66)(H,55,67)(H,57,68)(H,58,64)(H,59,65)(H,60,69)(H,61,70)/t31-,32+,39-,42+,43-,44+/m0/s1 MXGNDYOQTAQUSS-WAAXONQBSA-N 50166348 2-Amino-N-(1-{[(1-{(S)-2-[(R)-2-(2-{(S)-2-[1-amino-2-((R)-4-hydroxy-phenyl)-ethylamino]-propionylamino}-acetylamino)-3-phenyl-propionylamino]-phenylcarbamoyl}-2-phenyl-ethylcarbamoyl)-methyl]-carbamoyl}-ethyl)-3-((R)-4-hydroxy-phenyl)-propionamide; ditrifluoroacetic acid::CHEMBL408601 Mu-type opioid receptor Cavia cutleri 40 ChEMBL 10.1016/j.bmcl.2005.03.067 10.7270/Q22Z169S 15863299 Mollica, A; Davis, P; Ma, SW; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50166348 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50166348&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44401649 104051829 CHEMBL408601 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50839887 COc1ccc2CC3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35NC(=O)\C=C\c1ccccc1Cl InChI=1S/C30H31ClN2O4/c1-36-23-10-8-20-16-24-30(32-25(35)11-9-19-4-2-3-5-21(19)31)13-12-22(34)28-29(30,26(20)27(23)37-28)14-15-33(24)17-18-6-7-18/h2-5,8-11,18,24,28H,6-7,12-17H2,1H3,(H,32,35)/b11-9+/t24?,28-,29-,30+/m0/s1 DAGJGFYYIBDDIY-WMZOMSSISA-N 50193543 N-cyclopropylmethyl-14beta-(2'-chlorocinnamoylamino)-7,8-dihydronorcodeinone Mu-type opioid receptor Cavia cutleri 0.600000 ChEMBL 10.1021/jm0604777 10.7270/Q2WH2QSM 16913723 Nieland, NP; Moynihan, HA; Carrington, S; Broadbear, J; Woods, JH; Traynor, JR; Husbands, SM; Lewis, JW University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193543&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44415311 104075982 ZINC36221947 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50839911 COc1ccc2CC3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35NC(=O)\C=C\c1ccccc1C InChI=1S/C31H34N2O4/c1-19-5-3-4-6-21(19)10-12-26(35)32-31-14-13-23(34)29-30(31)15-16-33(18-20-7-8-20)25(31)17-22-9-11-24(36-2)28(37-29)27(22)30/h3-6,9-12,20,25,29H,7-8,13-18H2,1-2H3,(H,32,35)/b12-10+/t25?,29-,30-,31+/m0/s1 HKFWFMQRXDJWRR-RNGWUSNQSA-N 50193536 N-cyclopropylmethyl-14beta-(2'-methylcinnamoylamino)-7,8-dihydronorcodeinone Mu-type opioid receptor Cavia cutleri 0.200000 ChEMBL 10.1021/jm0604777 10.7270/Q2WH2QSM 16913723 Nieland, NP; Moynihan, HA; Carrington, S; Broadbear, J; Woods, JH; Traynor, JR; Husbands, SM; Lewis, JW University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193536 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193536&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44415131 104075975 ZINC36221945 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50838789 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C32H37N5O5/c33-25(18-23-13-15-24(38)16-14-23)32(42)37-17-7-12-28(37)31(41)36-27(20-22-10-5-2-6-11-22)30(40)35-26(29(34)39)19-21-8-3-1-4-9-21/h1-6,8-11,13-16,25-28,38H,7,12,17-20,33H2,(H2,34,39)(H,35,40)(H,36,41)/t25-,26-,27-,28-/m0/s1 XIJHWXXXIMEHKW-LJWNLINESA-N 50139013 (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::(S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxamide::1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylicacid[1-((S)-(S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL333357::H-Tyr-Pro-Phe-Phe-NH2::Tyr-Pro-Phe-Phe-NH2::endomorphin-2 Mu-type opioid receptor Cavia cutleri 14 ChEMBL 10.1021/jm0603264 10.7270/Q2474BPW 16789756 Ballet, S; Salvadori, S; Trapella, C; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Negri, L; Giannini, E; Lattanzi, R; Tourwe, D; Balboni, G Vrije Universiteit Brussels http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139013&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311081 104029000 CHEMBL333357 3668 ZINC14951634 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50838794 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H]1Cc2ccccc2CN(CC(=O)Nc2ccccc2)C1=O InChI=1S/C29H32N4O4/c1-18-12-23(34)13-19(2)24(18)15-25(30)28(36)32-26-14-20-8-6-7-9-21(20)16-33(29(26)37)17-27(35)31-22-10-4-3-5-11-22/h3-13,25-26,34H,14-17,30H2,1-2H3,(H,31,35)(H,32,36)/t25-,26-/m0/s1 JYNUREYKNAJNLW-UIOOFZCWSA-N 50189921 CHEMBL377392::H-Dmt-Aba-Gly-NH-Ph Mu-type opioid receptor Cavia cutleri 95 ChEMBL 10.1021/jm0603264 10.7270/Q2474BPW 16789756 Ballet, S; Salvadori, S; Trapella, C; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Negri, L; Giannini, E; Lattanzi, R; Tourwe, D; Balboni, G Vrije Universiteit Brussels http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189921 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189921&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11635818 104073373 CHEMBL377392 ZINC35975477 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50838798 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCC(=O)Nc1ccccc1 InChI=1S/C29H32N4O4/c1-18-12-23(34)13-19(2)24(18)15-25(30)29(37)33-17-21-9-7-6-8-20(21)14-26(33)28(36)31-16-27(35)32-22-10-4-3-5-11-22/h3-13,25-26,34H,14-17,30H2,1-2H3,(H,31,36)(H,32,35)/t25-,26-/m0/s1 JQERUKPESNWSQA-UIOOFZCWSA-N 50272081 2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid phenylcarbamoylmethyl-amide::CHEMBL501451::H-Dmt-Tic-Gly-NH-Ph Mu-type opioid receptor Cavia cutleri 2.6 ChEMBL 10.1021/jm0603264 10.7270/Q2474BPW 16789756 Ballet, S; Salvadori, S; Trapella, C; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Negri, L; Giannini, E; Lattanzi, R; Tourwe, D; Balboni, G Vrije Universiteit Brussels http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50272081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50272081&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11016572 104116589 CHEMBL501451 ZINC13472300 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50838799 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCC(=O)NCc1ccccc1 InChI=1S/C30H34N4O4/c1-19-12-24(35)13-20(2)25(19)15-26(31)30(38)34-18-23-11-7-6-10-22(23)14-27(34)29(37)33-17-28(36)32-16-21-8-4-3-5-9-21/h3-13,26-27,35H,14-18,31H2,1-2H3,(H,32,36)(H,33,37)/t26-,27-/m0/s1 SYOVEDOWOXNOJG-SVBPBHIXSA-N 50266025 (S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-N-(2-(benzylamino)-2-oxoethyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid (benzylcarbamoyl-methyl)-amide::CHEMBL458631::H-Dmt-Tic-Gly-NH-Bzl::H-Dmt-Tic-Gly-NH-CH2-Ph Mu-type opioid receptor Cavia cutleri 2.7 ChEMBL 10.1021/jm0603264 10.7270/Q2474BPW 16789756 Ballet, S; Salvadori, S; Trapella, C; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Negri, L; Giannini, E; Lattanzi, R; Tourwe, D; Balboni, G Vrije Universiteit Brussels http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50266025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50266025&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10864183 104113557 CHEMBL458631 ZINC13472301 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50838800 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H]1Cc2ccccc2CN(CC(=O)NCc2ccccc2)C1=O InChI=1S/C30H34N4O4/c1-19-12-24(35)13-20(2)25(19)15-26(31)29(37)33-27-14-22-10-6-7-11-23(22)17-34(30(27)38)18-28(36)32-16-21-8-4-3-5-9-21/h3-13,26-27,35H,14-18,31H2,1-2H3,(H,32,36)(H,33,37)/t26-,27-/m0/s1 HAQFBGNRXYPSQF-SVBPBHIXSA-N 50189920 (S)-2-amino-N-((S)-2-(2-(benzylamino)-2-oxoethyl)-3-oxo-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-yl)-3-(4-hydroxy-2,6-dimethylphenyl)propanamide::CHEMBL208683::H-Dmt-Aba-Gly-NH-CH2-Ph Mu-type opioid receptor Cavia cutleri 51 ChEMBL 10.1021/jm0603264 10.7270/Q2474BPW 16789756 Ballet, S; Salvadori, S; Trapella, C; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Negri, L; Giannini, E; Lattanzi, R; Tourwe, D; Balboni, G Vrije Universiteit Brussels http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189920&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11664525 104073372 CHEMBL208683 ZINC36221912 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50838810 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H]1Cc2ccccc2CN(Cc2nc3ccccc3[nH]2)C1=O InChI=1S/C29H31N5O3/c1-17-11-21(35)12-18(2)22(17)14-23(30)28(36)33-26-13-19-7-3-4-8-20(19)15-34(29(26)37)16-27-31-24-9-5-6-10-25(24)32-27/h3-12,23,26,35H,13-16,30H2,1-2H3,(H,31,32)(H,33,36)/t23-,26-/m0/s1 KNVMNIVKKSUNLC-OZXSUGGESA-N 50189918 CHEMBL211543::H-Dmt-Aba-Gly-NH-CH2-Bid Mu-type opioid receptor Cavia cutleri 231 ChEMBL 10.1021/jm0603264 10.7270/Q2474BPW 16789756 Ballet, S; Salvadori, S; Trapella, C; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Negri, L; Giannini, E; Lattanzi, R; Tourwe, D; Balboni, G Vrije Universiteit Brussels http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189918&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11721803 104073371 CHEMBL211543 ZINC34644465 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50840149 Cc1cc(O)cc(C)c1CC(N)C(=O)N1Cc2ccccc2CC1C(=O)NC(CCCCN)c1nc2ccccc2[nH]1 InChI=1S/C33H40N6O3/c1-20-15-24(40)16-21(2)25(20)18-26(35)33(42)39-19-23-10-4-3-9-22(23)17-30(39)32(41)38-29(13-7-8-14-34)31-36-27-11-5-6-12-28(27)37-31/h3-6,9-12,15-16,26,29-30,40H,7-8,13-14,17-19,34-35H2,1-2H3,(H,36,37)(H,38,41) GDHJQGJCKHJHHZ-UHFFFAOYSA-N 50194237 CHEMBL377960::H-Dmt-Tic-NH-CH[(CH2)4-NH2]-Bid Mu-type opioid receptor Cavia cutleri 39.7 ChEMBL 10.1021/jm060741w 10.7270/Q2416XTD 16942034 Balboni, G; Onnis, V; Congiu, C; Zotti, M; Sasaki, Y; Ambo, A; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Trapella, C; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50194237 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50194237&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25050224 104076568 CHEMBL377960 ZINC36216297 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50840154 CC(=O)NCCCCC(NC(=O)C1Cc2ccccc2CN1C(=O)C(N)Cc1c(C)cc(O)cc1C)c1nc2ccccc2[nH]1 InChI=1S/C35H42N6O4/c1-21-16-26(43)17-22(2)27(21)19-28(36)35(45)41-20-25-11-5-4-10-24(25)18-32(41)34(44)40-31(14-8-9-15-37-23(3)42)33-38-29-12-6-7-13-30(29)39-33/h4-7,10-13,16-17,28,31-32,43H,8-9,14-15,18-20,36H2,1-3H3,(H,37,42)(H,38,39)(H,40,44) IOSGXZKTOLVOTQ-UHFFFAOYSA-N 50194242 CHEMBL378082::H-Dmt-Tic-NH-CH[(CH2)4-NH-Ac]-Bid Mu-type opioid receptor Cavia cutleri 53.9 ChEMBL 10.1021/jm060741w 10.7270/Q2416XTD 16942034 Balboni, G; Onnis, V; Congiu, C; Zotti, M; Sasaki, Y; Ambo, A; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Trapella, C; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50194242 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50194242&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25050370 104076573 CHEMBL378082 ZINC36216285 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50840158 Cc1cc(O)cc(C)c1CC(N)C(=O)N1Cc2ccccc2CC1C(=O)NC(CCCCNC(=O)OCc1ccccc1)c1nc2ccccc2[nH]1 InChI=1S/C41H46N6O5/c1-26-20-31(48)21-27(2)32(26)23-33(42)40(50)47-24-30-15-7-6-14-29(30)22-37(47)39(49)46-36(38-44-34-16-8-9-17-35(34)45-38)18-10-11-19-43-41(51)52-25-28-12-4-3-5-13-28/h3-9,12-17,20-21,33,36-37,48H,10-11,18-19,22-25,42H2,1-2H3,(H,43,51)(H,44,45)(H,46,49) ZHRKDWCBKIOLKI-UHFFFAOYSA-N 50194238 CHEMBL386309::H-Dmt-Tic-NH-CH[(CH2)4-NH-Z]-Bid Mu-type opioid receptor Cavia cutleri 375 ChEMBL 10.1021/jm060741w 10.7270/Q2416XTD 16942034 Balboni, G; Onnis, V; Congiu, C; Zotti, M; Sasaki, Y; Ambo, A; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Trapella, C; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50194238 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50194238&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25050223 104076569 CHEMBL386309 ZINC49780159 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50840170 Cc1cc(O)cc(C)c1CC(N)C(=O)N1Cc2ccccc2CC1C(=O)N[C@H](CCCCNC(=O)OCc1ccccc1)c1nc2ccccc2[nH]1 InChI=1S/C41H46N6O5/c1-26-20-31(48)21-27(2)32(26)23-33(42)40(50)47-24-30-15-7-6-14-29(30)22-37(47)39(49)46-36(38-44-34-16-8-9-17-35(34)45-38)18-10-11-19-43-41(51)52-25-28-12-4-3-5-13-28/h3-9,12-17,20-21,33,36-37,48H,10-11,18-19,22-25,42H2,1-2H3,(H,43,51)(H,44,45)(H,46,49)/t33?,36-,37?/m1/s1 ZHRKDWCBKIOLKI-QNUATKLTSA-N 50194244 CHEMBL212172::H-Dmt-Tic-NH-(D)-CH[(CH2)4-NH-Z]-Bid Mu-type opioid receptor Cavia cutleri 62.5 ChEMBL 10.1021/jm060741w 10.7270/Q2416XTD 16942034 Balboni, G; Onnis, V; Congiu, C; Zotti, M; Sasaki, Y; Ambo, A; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Trapella, C; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50194244 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50194244&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16082947 104076575 CHEMBL212172 ZINC49938403 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50840177 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C32H37N5O5/c33-25(18-23-13-15-24(38)16-14-23)32(42)37-17-7-12-28(37)31(41)36-27(20-22-10-5-2-6-11-22)30(40)35-26(29(34)39)19-21-8-3-1-4-9-21/h1-6,8-11,13-16,25-28,38H,7,12,17-20,33H2,(H2,34,39)(H,35,40)(H,36,41)/t25-,26-,27-,28-/m0/s1 XIJHWXXXIMEHKW-LJWNLINESA-N 50139013 (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::(S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxamide::1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylicacid[1-((S)-(S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL333357::H-Tyr-Pro-Phe-Phe-NH2::Tyr-Pro-Phe-Phe-NH2::endomorphin-2 Mu-type opioid receptor Cavia cutleri 13.7 ChEMBL 10.1021/jm060741w 10.7270/Q2416XTD 16942034 Balboni, G; Onnis, V; Congiu, C; Zotti, M; Sasaki, Y; Ambo, A; Bryant, SD; Jinsmaa, Y; Lazarus, LH; Trapella, C; Salvadori, S University of Cagliari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139013&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311081 104029000 CHEMBL333357 3668 ZINC14951634 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50847729 O[C@@H]1CCC2CN(CCc3ccccc3)C1CN2Cc1ccccc1 InChI=1S/C22H28N2O/c25-22-12-11-20-16-23(14-13-18-7-3-1-4-8-18)21(22)17-24(20)15-19-9-5-2-6-10-19/h1-10,20-22,25H,11-17H2/t20?,21?,22-/m1/s1 KNLILHFSKCATHQ-LZBANZJXSA-N 50210183 (1R,2S,5S )-6-Benzyl-8-(2-phenylethyl)-6,8-diazabidiazabicyclo::CHEMBL395304 Mu-type opioid receptor Cavia cutleri 4960 ChEMBL 10.1016/j.ejmech.2007.02.005 10.7270/Q2BP03MX 17420073 Weigl, M; Wunsch, B Institut f£r Pharmazeutische und Medizinische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210183 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210183&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44428288 104086748 CHEMBL395304 ZINC36286648 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50847735 Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1 UZHSEJADLWPNLE-GRGSLBFTSA-N 50000788 (morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(naloxone) 4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::(naloxone)4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::(naloxone)4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one (naloxone)::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one( Naloxone)::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(Naxolone)::4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(naloxone)C2H2O4::Analog of 14-(Arylhydroxyamino)codeinone::NALOXONE::NARCAN::SUBOXONE::[17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydroxymorphinan-6-one Mu-type opioid receptor Cavia cutleri 0.68 ChEMBL 10.1016/j.ejmech.2007.02.005 10.7270/Q2BP03MX 17420073 Weigl, M; Wunsch, B Institut f£r Pharmazeutische und Medizinische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000788&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5284596 103915330 7459 DB01183 1676 C07252 ZINC00389747 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50847747 O[C@H]1CCC2CN(CCc3ccccc3)C1CN2Cc1ccccc1 InChI=1S/C22H28N2O/c25-22-12-11-20-16-23(14-13-18-7-3-1-4-8-18)21(22)17-24(20)15-19-9-5-2-6-10-19/h1-10,20-22,25H,11-17H2/t20?,21?,22-/m0/s1 KNLILHFSKCATHQ-HRTMPFAESA-N 50210184 (1R,2R,5S )-6-benzyl-8-(2-phenylethyl)-6,8-diazabicyclo[3.2.2]nonan-2-ol::CHEMBL242077 Mu-type opioid receptor Cavia cutleri 4050 ChEMBL 10.1016/j.ejmech.2007.02.005 10.7270/Q2BP03MX 17420073 Weigl, M; Wunsch, B Institut f£r Pharmazeutische und Medizinische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210184 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210184&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44428289 104086749 CHEMBL242077 ZINC36286651 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50845227 OC(=O)CN1CCN(CCn2c3[C@H]4Oc5c6c(C[C@H]7N(CC8CC8)CC[C@@]46[C@@]7(O)Cc3c3ccccc23)ccc5O)CCN(CC(O)=O)CCN(CC(O)=O)CC1 InChI=1S/C42H54N6O9/c49-32-8-7-28-21-33-42(56)22-30-29-3-1-2-4-31(29)48(38(30)40-41(42,37(28)39(32)57-40)9-10-47(33)23-27-5-6-27)20-19-43-11-13-44(24-34(50)51)15-17-46(26-36(54)55)18-16-45(14-12-43)25-35(52)53/h1-4,7-8,27,33,40,49,56H,5-6,9-26H2,(H,50,51)(H,52,53)(H,54,55)/t33-,40-,41+,42-/m1/s1 LPTQLPVGJXPHOP-WUCGYPQFSA-N 50209645 17-(cyclopropylmethyl)-6,7-didehydro-4,5alpha-epoxy-3,14-dihydroxy-1'-(10'''-[3''-propyl]-[1''',4''',7''',10'''-tetraazacyclododecane-1''',4''',7'''-triacetic acid])indolo[6,7:2',3']morphinan::CHEMBL390173 Mu-type opioid receptor Cavia cutleri 1748 ChEMBL 10.1021/jm0700013 10.7270/Q2HQ40RW 17402725 Duval, RA; Allmon, RL; Lever, JR University of Missouri-Columbia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209645 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209645&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44422815 104086382 CHEMBL390173 ZINC95543782 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50845230 OC(=O)CN1CCN(CCCCCn2c3[C@H]4Oc5c6c(C[C@H]7N(CC8CC8)CC[C@@]46[C@@]7(O)Cc3c3ccccc23)ccc5O)CCN(CC(O)=O)CCN(CC(O)=O)CC1 InChI=1S/C45H60N6O9/c52-35-11-10-31-24-36-45(59)25-33-32-6-2-3-7-34(32)51(41(33)43-44(45,40(31)42(35)60-43)12-15-50(36)26-30-8-9-30)14-5-1-4-13-46-16-18-47(27-37(53)54)20-22-49(29-39(57)58)23-21-48(19-17-46)28-38(55)56/h2-3,6-7,10-11,30,36,43,52,59H,1,4-5,8-9,12-29H2,(H,53,54)(H,55,56)(H,57,58)/t36-,43-,44+,45-/m1/s1 PIRQXHBJZXLQDF-WRMSQNFHSA-N 50209644 17-cyclopropylmethyl)-6,7-didehydro-4,5alpha-epoxy-3,14-dihydroxy-1'-(10'''-[6''-hexyl]-[1''',4''',7''',10'''-tetraazacyclododecane-1''',4''',7'''-triacetic acid])indolo[6,7:2',3']morphinan::CHEMBL426750 Mu-type opioid receptor Cavia cutleri 48.2 ChEMBL 10.1021/jm0700013 10.7270/Q2HQ40RW 17402725 Duval, RA; Allmon, RL; Lever, JR University of Missouri-Columbia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209644&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44422816 104086381 CHEMBL426750 ZINC95614492 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50845231 Oc1ccc2C[C@H]3N(CC4CC4)CCC45C(Oc1c24)c1[nH]c2ccccc2c1CC35O InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1 WIYUZYBFCWCCQJ-XEWUMVRVSA-N 21864 (21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.0^{1,13}.0^{2,21}.0^{4,12}.0^{5,10}.0^{19,25}]pentacosa-4(12),5,7,9,15,17,19(25)-heptaene-2,16-diol::(8R)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol::NALTRINDOLE::[3H]-naltrindole Mu-type opioid receptor Cavia cutleri 33.9 ChEMBL 10.1021/jm0700013 10.7270/Q2HQ40RW 17402725 Duval, RA; Allmon, RL; Lever, JR University of Missouri-Columbia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21864&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3034754 49700969 ZINC62153992 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50847756 CCCCN1CC2CCC(OCc3ccccc3)C1CN2Cc1ccccc1 InChI=1S/C25H34N2O/c1-2-3-16-26-18-23-14-15-25(28-20-22-12-8-5-9-13-22)24(26)19-27(23)17-21-10-6-4-7-11-21/h4-13,23-25H,2-3,14-20H2,1H3 BAWRLAUIQOALAY-UHFFFAOYSA-N 50210181 6-benzyl-2-(benzyloxy)-8-butyl-6,8-diaza-bicyclo[3.2.2]nonane::CHEMBL429103 Mu-type opioid receptor Cavia cutleri 3320 ChEMBL 10.1016/j.ejmech.2007.02.005 10.7270/Q2BP03MX 17420073 Weigl, M; Wunsch, B Institut f£r Pharmazeutische und Medizinische Chemie http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210181&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44428294 104086746 CHEMBL429103 ZINC36286658 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50839496 COc1ccc2C[C@@H]3[C@@H]4CC[C@H](OS([O-])(=O)=O)[C@@H]5Oc1c2[C@]45CC[NH+]3C InChI=1S/C18H23NO6S/c1-19-8-7-18-11-4-6-14(25-26(20,21)22)17(18)24-16-13(23-2)5-3-10(15(16)18)9-12(11)19/h3,5,11-12,14,17H,4,6-9H2,1-2H3,(H,20,21,22)/t11-,12+,14-,17-,18-/m0/s1 UFGYWOICNCSHBB-XSSYPUMDSA-N 50189245 CHEMBL1416::DC6S Mu-type opioid receptor Cavia cutleri 196 ChEMBL 10.1016/j.bmcl.2006.05.060 10.7270/Q2XG9RXF 16777416 Crooks, PA; Kottayil, SG; Al-Ghananeem, AM; Byrn, SR; Butterfield, DA University of Kentucky http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189245 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189245&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44414724 104072931 CHEMBL1416 C02000 ZINC36221923 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50839500 CC(C)C(=O)Oc1ccc2C[C@@H]3[C@@H]4C=C[C@H](OS([O-])(=O)=O)[C@@H]5Oc1c2[C@]45CC[NH+]3C InChI=1S/C21H25NO7S/c1-11(2)20(23)27-15-6-4-12-10-14-13-5-7-16(29-30(24,25)26)19-21(13,8-9-22(14)3)17(12)18(15)28-19/h4-7,11,13-14,16,19H,8-10H2,1-3H3,(H,24,25,26)/t13-,14+,16-,19-,21-/m0/s1 GABBKMMVICEZHE-AYHJQLAQSA-N 50189249 CHEMBL211576::M3IBu6S Mu-type opioid receptor Cavia cutleri 20 ChEMBL 10.1016/j.bmcl.2006.05.060 10.7270/Q2XG9RXF 16777416 Crooks, PA; Kottayil, SG; Al-Ghananeem, AM; Byrn, SR; Butterfield, DA University of Kentucky http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189249 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189249&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44414863 104072935 CHEMBL211576 C02000 ZINC36221937 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50839516 CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C27H35N5O7S/c1-40-12-11-21(27(38)39)32-26(37)22(14-17-5-3-2-4-6-17)31-24(35)16-29-23(34)15-30-25(36)20(28)13-18-7-9-19(33)10-8-18/h2-10,20-22,33H,11-16,28H2,1H3,(H,29,34)(H,30,36)(H,31,35)(H,32,37)(H,38,39)/t20-,21-,22-/m0/s1 YFGBQHOOROIVKG-FKBYEOEOSA-N 50019056 (S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methylsulfanyl-butyric acid::([Met]-enkephalin)2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methylsulfanyl-butyric acid([Met]-enkephalin::2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-1-oxo-3-phenyl-propylamino]-4-methylsulfanyl-butyric acid::2-[1-[1-amino-2-(4-hydroxyphenyl)-(1S)-ethylcarboxamidomethylcarboxamidomethylcarboxamido]-2-phenyl-(1S)-ethylcarboxamido]-4-methylsulfanyl-(2S)-butanoic acid::2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methylsulfanyl-butyric acid::CHEMBL13786::H-Tyr-Gly-Gly-Phe-Met-OH::Met5-Enkephalin::[Met5]-enkephalin::met-enkephalin Mu-type opioid receptor Cavia cutleri 6.9 ChEMBL 10.1016/j.bmcl.2006.05.060 10.7270/Q2XG9RXF 16777416 Crooks, PA; Kottayil, SG; Al-Ghananeem, AM; Byrn, SR; Butterfield, DA University of Kentucky http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019056 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019056&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 443363 103930098 CHEMBL13786 1614 C11684 ZINC53147203 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50839517 C[NH+]1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4OS([O-])(=O)=O)ccc5OC(=O)C(C)(C)C InChI=1S/C22H27NO7S/c1-21(2,3)20(24)28-15-7-5-12-11-14-13-6-8-16(30-31(25,26)27)19-22(13,9-10-23(14)4)17(12)18(15)29-19/h5-8,13-14,16,19H,9-11H2,1-4H3,(H,25,26,27)/t13-,14+,16-,19-,22-/m0/s1 NEUKRIIKAHFBFQ-JYSMHPMOSA-N 50189251 CHEMBL213228::M3P6S Mu-type opioid receptor Cavia cutleri 0.700000 ChEMBL 10.1016/j.bmcl.2006.05.060 10.7270/Q2XG9RXF 16777416 Crooks, PA; Kottayil, SG; Al-Ghananeem, AM; Byrn, SR; Butterfield, DA University of Kentucky http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189251 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189251&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44414864 104072937 CHEMBL213228 C02000 ZINC36221931 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50839524 CC1(C)SSC(C)(C)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)NCC(=O)N[C@@H](Cc2ccc(Cl)cc2)C(=O)N[C@H]1C(O)=O InChI=1S/C30H38ClN5O7S2/c1-29(2)23(35-25(39)20(32)13-16-7-11-19(37)12-8-16)27(41)33-15-22(38)34-21(14-17-5-9-18(31)10-6-17)26(40)36-24(28(42)43)30(3,4)45-44-29/h5-12,20-21,23-24,37H,13-15,32H2,1-4H3,(H,33,41)(H,34,38)(H,35,39)(H,36,40)(H,42,43)/t20-,21-,23-,24-/m0/s1 VTVUYFFDQHWCTJ-WMIMKTLMSA-N 50068133 (4S,7S,13S)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-(4-chloro-benzyl)-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid::CHEMBL143939 Mu-type opioid receptor Cavia cutleri 180 ChEMBL 10.1016/j.bmcl.2006.05.060 10.7270/Q2XG9RXF 16777416 Crooks, PA; Kottayil, SG; Al-Ghananeem, AM; Byrn, SR; Butterfield, DA University of Kentucky http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068133 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068133&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 159564 103962469 CHEMBL143939 ZINC58512951 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50839525 Oc1ccc2CC3N(CC=C)CCC45[C@H](Oc1c24)C(CCC35O)=NNC(=O)c1ccccc1 InChI=1S/C26H27N3O4/c1-2-13-29-14-12-25-21-17-8-9-19(30)22(21)33-23(25)18(10-11-26(25,32)20(29)15-17)27-28-24(31)16-6-4-3-5-7-16/h2-9,20,23,30,32H,1,10-15H2,(H,28,31)/t20?,23-,25?,26?/m1/s1 AKXCFAYOTIEFOH-MJZKPUTMSA-N 50189257 CHEMBL378753::NalBzOH Mu-type opioid receptor Cavia cutleri 0.200000 ChEMBL 10.1016/j.bmcl.2006.05.060 10.7270/Q2XG9RXF 16777416 Crooks, PA; Kottayil, SG; Al-Ghananeem, AM; Byrn, SR; Butterfield, DA University of Kentucky http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189257&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44414890 104072943 CHEMBL378753 ZINC03874473 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50839527 C[N+]1(C)CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4OS([O-])(=O)=O)ccc5OC(=O)c1ccccc1 InChI=1S/C25H25NO7S/c1-26(2)13-12-25-17-9-11-20(33-34(28,29)30)23(25)32-22-19(10-8-16(21(22)25)14-18(17)26)31-24(27)15-6-4-3-5-7-15/h3-11,17-18,20,23H,12-14H2,1-2H3/t17-,18+,20-,23-,25-/m0/s1 RMPWVEGPFQZBPZ-SDSLYQAOSA-N 50189248 CHEMBL211374::MM3B6S Mu-type opioid receptor Cavia cutleri 444 ChEMBL 10.1016/j.bmcl.2006.05.060 10.7270/Q2XG9RXF 16777416 Crooks, PA; Kottayil, SG; Al-Ghananeem, AM; Byrn, SR; Butterfield, DA University of Kentucky http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189248 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189248&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44414811 104072934 CHEMBL211374 C02000 ZINC36311375 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50839529 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 2.5 ChEMBL 10.1016/j.bmcl.2006.05.060 10.7270/Q2XG9RXF 16777416 Crooks, PA; Kottayil, SG; Al-Ghananeem, AM; Byrn, SR; Butterfield, DA University of Kentucky http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50839533 C[NH+]1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4OS([O-])(=O)=O)ccc5O InChI=1S/C17H19NO6S/c1-18-7-6-17-10-3-5-13(24-25(20,21)22)16(17)23-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19H,6-8H2,1H3,(H,20,21,22)/t10-,11+,13-,16-,17-/m0/s1 FSUXDJDFTDDUJZ-KBQPJGBKSA-N 50189247 CHEMBL1418::M6S Mu-type opioid receptor Cavia cutleri 0.900000 ChEMBL 10.1016/j.bmcl.2006.05.060 10.7270/Q2XG9RXF 16777416 Crooks, PA; Kottayil, SG; Al-Ghananeem, AM; Byrn, SR; Butterfield, DA University of Kentucky http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189247&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44414829 104072933 CHEMBL1418 C02000 ZINC05699861 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50839540 CCC(=O)Oc1ccc2C[C@@H]3[C@@H]4C=C[C@H](OS([O-])(=O)=O)[C@@H]5Oc1c2[C@]45CC[NH+]3C InChI=1S/C20H23NO7S/c1-3-16(22)26-14-6-4-11-10-13-12-5-7-15(28-29(23,24)25)19-20(12,8-9-21(13)2)17(11)18(14)27-19/h4-7,12-13,15,19H,3,8-10H2,1-2H3,(H,23,24,25)/t12-,13+,15-,19-,20-/m0/s1 LWKYBVFQVUJKDT-ILIJTDRLSA-N 50189256 CHEMBL385048::M3Pr6S Mu-type opioid receptor Cavia cutleri 0.600000 ChEMBL 10.1016/j.bmcl.2006.05.060 10.7270/Q2XG9RXF 16777416 Crooks, PA; Kottayil, SG; Al-Ghananeem, AM; Byrn, SR; Butterfield, DA University of Kentucky http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189256&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44414843 104072942 CHEMBL385048 C02000 ZINC36221929 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50839542 C[NH+]1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5OS([O-])(=O)=O InChI=1S/C17H19NO6S/c1-18-7-6-17-10-3-4-12(19)16(17)23-15-13(24-25(20,21)22)5-2-9(14(15)17)8-11(10)18/h2-5,10-12,16,19H,6-8H2,1H3,(H,20,21,22)/t10-,11+,12-,16-,17-/m0/s1 UEMQCYWLMNLODZ-KOFBORESSA-N 50189254 CHEMBL1415::M3S Mu-type opioid receptor Cavia cutleri 101 ChEMBL 10.1016/j.bmcl.2006.05.060 10.7270/Q2XG9RXF 16777416 Crooks, PA; Kottayil, SG; Al-Ghananeem, AM; Byrn, SR; Butterfield, DA University of Kentucky http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189254&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44414680 104072940 CHEMBL1415 C02000 ZINC36311373 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50839547 C[NH+]1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3CC[C@@H]4OS([O-])(=O)=O)ccc5O InChI=1S/C17H21NO6S/c1-18-7-6-17-10-3-5-13(24-25(20,21)22)16(17)23-15-12(19)4-2-9(14(15)17)8-11(10)18/h2,4,10-11,13,16,19H,3,5-8H2,1H3,(H,20,21,22)/t10-,11+,13-,16-,17-/m0/s1 QTALQTUQMLSRSG-KBQPJGBKSA-N 50189258 CHEMBL385448::DM6S Mu-type opioid receptor Cavia cutleri 1.5 ChEMBL 10.1016/j.bmcl.2006.05.060 10.7270/Q2XG9RXF 16777416 Crooks, PA; Kottayil, SG; Al-Ghananeem, AM; Byrn, SR; Butterfield, DA University of Kentucky http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189258 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189258&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44414783 104072944 CHEMBL385448 C02000 ZINC36221925 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50839561 C[NH+]1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4OS([O-])(=O)=O)ccc5OC(C)=O InChI=1S/C19H21NO7S/c1-10(21)25-14-5-3-11-9-13-12-4-6-15(27-28(22,23)24)18-19(12,7-8-20(13)2)16(11)17(14)26-18/h3-6,12-13,15,18H,7-9H2,1-2H3,(H,22,23,24)/t12-,13+,15-,18-,19-/m0/s1 AVTOGXGTGWUJBM-SSTWWWIQSA-N 50189252 CHEMBL214040::M3A6S Mu-type opioid receptor Cavia cutleri 0.800000 ChEMBL 10.1016/j.bmcl.2006.05.060 10.7270/Q2XG9RXF 16777416 Crooks, PA; Kottayil, SG; Al-Ghananeem, AM; Byrn, SR; Butterfield, DA University of Kentucky http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189252 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189252&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44414842 104072938 CHEMBL214040 C02000 ZINC03976913 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50839563 C[NH+]1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4OS([O-])(=O)=O)ccc5OC(=O)c1ccccc1 InChI=1S/C24H23NO7S/c1-25-12-11-24-16-8-10-19(32-33(27,28)29)22(24)31-21-18(9-7-15(20(21)24)13-17(16)25)30-23(26)14-5-3-2-4-6-14/h2-10,16-17,19,22H,11-13H2,1H3,(H,27,28,29)/t16-,17+,19-,22-,24-/m0/s1 IQMPFHWIBSSPBS-MJFIPZRTSA-N 50189260 CHEMBL209751::M3B6S Mu-type opioid receptor Cavia cutleri 37 ChEMBL 10.1016/j.bmcl.2006.05.060 10.7270/Q2XG9RXF 16777416 Crooks, PA; Kottayil, SG; Al-Ghananeem, AM; Byrn, SR; Butterfield, DA University of Kentucky http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189260 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189260&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44414877 104072946 CHEMBL209751 C02000 ZINC36221939 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50839564 COc1ccc2C[C@@H]3[C@@H]4C=C[C@H](OS([O-])(=O)=O)[C@@H]5Oc1c2[C@]45CC[NH+]3C InChI=1S/C18H21NO6S/c1-19-8-7-18-11-4-6-14(25-26(20,21)22)17(18)24-16-13(23-2)5-3-10(15(16)18)9-12(11)19/h3-6,11-12,14,17H,7-9H2,1-2H3,(H,20,21,22)/t11-,12+,14-,17-,18-/m0/s1 JIYGLXDCNSTUSY-XSSYPUMDSA-N 50189259 C6S::CHEMBL1417 Mu-type opioid receptor Cavia cutleri 39 ChEMBL 10.1016/j.bmcl.2006.05.060 10.7270/Q2XG9RXF 16777416 Crooks, PA; Kottayil, SG; Al-Ghananeem, AM; Byrn, SR; Butterfield, DA University of Kentucky http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189259 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189259&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44414813 104072945 CHEMBL1417 C02000 ZINC36221933 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50839567 C[NH+]1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3CC[C@@H]4OS([O-])(=O)=O)ccc5OC(=O)c1ccccc1 InChI=1S/C24H25NO7S/c1-25-12-11-24-16-8-10-19(32-33(27,28)29)22(24)31-21-18(9-7-15(20(21)24)13-17(16)25)30-23(26)14-5-3-2-4-6-14/h2-7,9,16-17,19,22H,8,10-13H2,1H3,(H,27,28,29)/t16-,17+,19-,22-,24-/m0/s1 YEYZQNSVGVDYOU-MJFIPZRTSA-N 50189253 CHEMBL213737::DM3B6S Mu-type opioid receptor Cavia cutleri 62 ChEMBL 10.1016/j.bmcl.2006.05.060 10.7270/Q2XG9RXF 16777416 Crooks, PA; Kottayil, SG; Al-Ghananeem, AM; Byrn, SR; Butterfield, DA University of Kentucky http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189253 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189253&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44414801 104072939 CHEMBL213737 C02000 ZINC36221935 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50839570 C[NH+]1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3CC[C@@H]4OS([O-])(=O)=O)ccc5OC(C)=O InChI=1S/C19H23NO7S/c1-10(21)25-14-5-3-11-9-13-12-4-6-15(27-28(22,23)24)18-19(12,7-8-20(13)2)16(11)17(14)26-18/h3,5,12-13,15,18H,4,6-9H2,1-2H3,(H,22,23,24)/t12-,13+,15-,18-,19-/m0/s1 YATYBWXTHXFYJT-SSTWWWIQSA-N 50189246 CHEMBL437682::DM3A6S Mu-type opioid receptor Cavia cutleri 14 ChEMBL 10.1016/j.bmcl.2006.05.060 10.7270/Q2XG9RXF 16777416 Crooks, PA; Kottayil, SG; Al-Ghananeem, AM; Byrn, SR; Butterfield, DA University of Kentucky http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189246 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189246&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44414785 104072932 CHEMBL437682 C02000 ZINC36221927 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50839571 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C)[C@@H](Cc1ccccc1)C(=O)NCCO InChI=1S/C26H35N5O6/c1-17(30-25(36)21(27)14-19-8-10-20(33)11-9-19)24(35)29-16-23(34)31(2)22(26(37)28-12-13-32)15-18-6-4-3-5-7-18/h3-11,17,21-22,32-33H,12-16,27H2,1-2H3,(H,28,37)(H,29,35)(H,30,36)/t17-,21+,22+/m1/s1 HPZJMUBDEAMBFI-WTNAPCKOSA-N 21015 (2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]-N-methylacetamido}-N-(2-hydroxyethyl)-3-phenylpropanamide::2-Ala-4-MePhe-5-Gly-Enkephalin::CHEMBL38874::D-Ala2-MePhe4-Met(0)5-enkephalin-ol::DAMGO::RX 783006::US11492374, ID 2::[3H]DAMGO::[tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephalin Mu-type opioid receptor Cavia cutleri 1.1 ChEMBL 10.1016/j.bmcl.2006.05.060 10.7270/Q2XG9RXF 16777416 Crooks, PA; Kottayil, SG; Al-Ghananeem, AM; Byrn, SR; Butterfield, DA University of Kentucky http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21015&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5462471 49689088 CHEMBL38874 1647 C04080 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50839574 CC(=O)Oc1ccc2C[C@@H]3[C@@H]4C=C[C@H](OS([O-])(=O)=O)[C@@H]5Oc1c2[C@]45CC[N+]3(C)C InChI=1S/C20H23NO7S/c1-11(22)26-15-6-4-12-10-14-13-5-7-16(28-29(23,24)25)19-20(13,8-9-21(14,2)3)17(12)18(15)27-19/h4-7,13-14,16,19H,8-10H2,1-3H3/t13-,14+,16-,19-,20-/m0/s1 QNHZSCHPVZZALI-BKRJIHRRSA-N 50189250 CHEMBL379928::MM3A6S Mu-type opioid receptor Cavia cutleri 34 ChEMBL 10.1016/j.bmcl.2006.05.060 10.7270/Q2XG9RXF 16777416 Crooks, PA; Kottayil, SG; Al-Ghananeem, AM; Byrn, SR; Butterfield, DA University of Kentucky http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189250 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189250&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10454860 104072936 CHEMBL379928 C02000 ZINC36221941 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50840997 COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35NCCCc1ccc(Cl)cc1 InChI=1S/C30H35ClN2O3/c1-35-24-11-8-21-17-25-30(32-15-2-3-19-6-9-22(31)10-7-19)13-12-23(34)28-29(30,26(21)27(24)36-28)14-16-33(25)18-20-4-5-20/h6-11,20,25,28,32H,2-5,12-18H2,1H3/t25-,28+,29+,30-/m1/s1 HEUWZOULKACFBC-ZBBWKFRYSA-N 50195660 CHEMBL384497::N-cyclopropylmethyl-14beta-[3'-(4'-chlorophenyl)propylamino]-7,8-dihydronorcodeinone Mu-type opioid receptor Cavia cutleri 0.590000 ChEMBL 10.1021/jm060595u 10.7270/Q24X58MF 17004724 Rennison, D; Moynihan, H; Traynor, JR; Lewis, JW; Husbands, SM University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50195660 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50195660&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16087287 104077656 CHEMBL384497 ZINC35050558 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50841015 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35NCCCc1ccc(Cl)cc1 InChI=1S/C29H33ClN2O3/c30-21-8-5-18(6-9-21)2-1-14-31-29-12-11-23(34)27-28(29)13-15-32(17-19-3-4-19)24(29)16-20-7-10-22(33)26(35-27)25(20)28/h5-10,19,24,27,31,33H,1-4,11-17H2/t24-,27+,28+,29-/m1/s1 ZHVLHUNBLJWDPM-ZLPBPMGLSA-N 50195666 CHEMBL443311::N-cyclopropylmethyl-14beta-[3'-(4'-chlorophenyl)propylamino]-7,8-dihydronormorphinone Mu-type opioid receptor Cavia cutleri 0.130000 ChEMBL 10.1021/jm060595u 10.7270/Q24X58MF 17004724 Rennison, D; Moynihan, H; Traynor, JR; Lewis, JW; Husbands, SM University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50195666 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50195666&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16087283 104077662 CHEMBL443311 ZINC35050554 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50841055 COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35NC\C=C\c1ccc(Cl)cc1 InChI=1S/C30H33ClN2O3/c1-35-24-11-8-21-17-25-30(32-15-2-3-19-6-9-22(31)10-7-19)13-12-23(34)28-29(30,26(21)27(24)36-28)14-16-33(25)18-20-4-5-20/h2-3,6-11,20,25,28,32H,4-5,12-18H2,1H3/b3-2+/t25-,28+,29+,30-/m1/s1 GVBJTHQLULFNPT-QOHCPDRESA-N 50195677 (1R,5R,13R,17S)-17-{[(2E)-3-(4-chlorophenyl)prop-2-en-1-yl]amino}-4-(cyclopropylmethyl)-10-methoxy-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10-trien-14-one::CHEMBL216251 Mu-type opioid receptor Cavia cutleri 0.700000 ChEMBL 10.1021/jm060595u 10.7270/Q24X58MF 17004724 Rennison, D; Moynihan, H; Traynor, JR; Lewis, JW; Husbands, SM University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50195677 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50195677&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44417384 104077673 CHEMBL216251 ZINC36221949 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50841067 COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35NC(=O)CCc1ccc(Cl)cc1 InChI=1S/C30H33ClN2O4/c1-36-23-10-7-20-16-24-30(32-25(35)11-6-18-4-8-21(31)9-5-18)13-12-22(34)28-29(30,26(20)27(23)37-28)14-15-33(24)17-19-2-3-19/h4-5,7-10,19,24,28H,2-3,6,11-17H2,1H3,(H,32,35)/t24-,28+,29+,30-/m1/s1 UJSYTVDGBUQRBX-QVDUQQMDSA-N 50195659 CHEMBL217395::N-cyclopropylmethyl-14beta-[3'-(4'-chlorophenyl)propanamido]-7,8-dihydronorcodeinone Mu-type opioid receptor Cavia cutleri 0.240000 ChEMBL 10.1021/jm060595u 10.7270/Q24X58MF 17004724 Rennison, D; Moynihan, H; Traynor, JR; Lewis, JW; Husbands, SM University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50195659 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50195659&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16087275 104077655 CHEMBL217395 ZINC35050549 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50841105 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35NC(=O)CCc1ccc(Cl)cc1 InChI=1S/C29H31ClN2O4/c30-20-7-3-17(4-8-20)5-10-24(35)31-29-12-11-22(34)27-28(29)13-14-32(16-18-1-2-18)23(29)15-19-6-9-21(33)26(36-27)25(19)28/h3-4,6-9,18,23,27,33H,1-2,5,10-16H2,(H,31,35)/t23-,27+,28+,29-/m1/s1 WYSHZXGBFZDQRH-FQYQUSJJSA-N 50195673 CHEMBL267027::N-cyclopropylmethyl-14beta-[3'-(4'-chlorophenyl)propanamido]-7,8-dihydronormorphinone Mu-type opioid receptor Cavia cutleri 0.040000 ChEMBL 10.1021/jm060595u 10.7270/Q24X58MF 17004724 Rennison, D; Moynihan, H; Traynor, JR; Lewis, JW; Husbands, SM University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50195673 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50195673&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16087270 104077669 CHEMBL267027 ZINC35050545 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50867299 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 29300 ChEMBL 10.1021/jm701404s 10.7270/Q27945JN 18370374 Ballet, S; Misicka, A; Kosson, P; Lemieux, C; Chung, NN; Schiller, PW; Lipkowski, AW; Tourwe, D Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50867302 C[C@@H](N1Cc2cc(O)ccc2C[C@H](N)C1=O)C(=O)N[C@H]1Cc2ccccc2CN(CC(N)=O)C1=O InChI=1S/C25H29N5O5/c1-14(30-12-18-8-19(31)7-6-16(18)9-20(26)24(30)34)23(33)28-21-10-15-4-2-3-5-17(15)11-29(25(21)35)13-22(27)32/h2-8,14,20-21,31H,9-13,26H2,1H3,(H2,27,32)(H,28,33)/t14-,20+,21+/m1/s1 ACFTTXWQZSBVGL-OREJSRFESA-N 50376593 CHEMBL409225::SB-0304 Mu-type opioid receptor Cavia cutleri 3640 ChEMBL 10.1021/jm701404s 10.7270/Q27945JN 18370374 Ballet, S; Misicka, A; Kosson, P; Lemieux, C; Chung, NN; Schiller, PW; Lipkowski, AW; Tourwe, D Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376593&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11641503 160855676 CHEMBL409225 ZINC29054110 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50867307 C[C@@H](N(C)C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N(C)CC(N)=O InChI=1S/C25H33N5O5/c1-16(30(3)24(34)20(26)13-18-9-11-19(31)12-10-18)23(33)28-21(14-17-7-5-4-6-8-17)25(35)29(2)15-22(27)32/h4-12,16,20-21,31H,13-15,26H2,1-3H3,(H2,27,32)(H,28,33)/t16-,20+,21+/m1/s1 GRHNSLXBGRDMSP-CZAAIQMYSA-N 50376594 CHEMBL260120 Mu-type opioid receptor Cavia cutleri 22000 ChEMBL 10.1021/jm701404s 10.7270/Q27945JN 18370374 Ballet, S; Misicka, A; Kosson, P; Lemieux, C; Chung, NN; Schiller, PW; Lipkowski, AW; Tourwe, D Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376594&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 24853671 160855677 CHEMBL260120 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50863892 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCc1nc2ccccc2[nH]1 InChI=1S/C29H31N5O3/c1-17-11-21(35)12-18(2)22(17)14-23(30)29(37)34-16-20-8-4-3-7-19(20)13-26(34)28(36)31-15-27-32-24-9-5-6-10-25(24)33-27/h3-12,23,26,35H,13-16,30H2,1-2H3,(H,31,36)(H,32,33)/t23-,26-/m0/s1 XRZTZWCPHAJWJQ-OZXSUGGESA-N 50179191 (S)-N-((1H-benzo[d]imidazol-2-yl)methyl)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid (1H-benzoimidazol-2-ylmethyl)-amide::CHEMBL109390::H-Dmt-Tic-NH-CH2-Bid::UFP-502 Mu-type opioid receptor Cavia cutleri 35.5 ChEMBL 10.1016/j.bmc.2007.12.032 10.7270/Q2NZ88H7 18178091 Salvadori, S; Fiorini, S; Trapella, C; Porreca, F; Davis, P; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Balboni, G University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179191&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10345770 104064419 CHEMBL109390 ZINC13472298 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50863897 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCc1cc2ccccc2[nH]1 InChI=1S/C30H32N4O3/c1-18-11-24(35)12-19(2)25(18)15-26(31)30(37)34-17-22-9-4-3-7-20(22)14-28(34)29(36)32-16-23-13-21-8-5-6-10-27(21)33-23/h3-13,26,28,33,35H,14-17,31H2,1-2H3,(H,32,36)/t26-,28-/m0/s1 WOVWFYGUXKNNEL-XCZPVHLTSA-N 50375294 CHEMBL408975 Mu-type opioid receptor Cavia cutleri 208.9 ChEMBL 10.1016/j.bmc.2007.12.032 10.7270/Q2NZ88H7 18178091 Salvadori, S; Fiorini, S; Trapella, C; Porreca, F; Davis, P; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Balboni, G University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375294 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375294&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44451665 160854384 CHEMBL408975 ZINC29062890 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50863910 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCc1ncc[nH]1 InChI=1S/C25H29N5O3/c1-15-9-19(31)10-16(2)20(15)12-21(26)25(33)30-14-18-6-4-3-5-17(18)11-22(30)24(32)29-13-23-27-7-8-28-23/h3-10,21-22,31H,11-14,26H2,1-2H3,(H,27,28)(H,29,32)/t21-,22-/m0/s1 PFUVPVAVWLKTQT-VXKWHMMOSA-N 50375295 CHEMBL407957 Mu-type opioid receptor Cavia cutleri 113.3 ChEMBL 10.1016/j.bmc.2007.12.032 10.7270/Q2NZ88H7 18178091 Salvadori, S; Fiorini, S; Trapella, C; Porreca, F; Davis, P; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Balboni, G University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375295 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375295&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44451610 160854385 CHEMBL407957 ZINC29062501 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50863911 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCc1nc(c[nH]1)-c1ccccc1 InChI=1S/C31H33N5O3/c1-19-12-24(37)13-20(2)25(19)15-26(32)31(39)36-18-23-11-7-6-10-22(23)14-28(36)30(38)34-17-29-33-16-27(35-29)21-8-4-3-5-9-21/h3-13,16,26,28,37H,14-15,17-18,32H2,1-2H3,(H,33,35)(H,34,38)/t26-,28-/m0/s1 LKMAEHUMCHTBER-XCZPVHLTSA-N 50375298 CHEMBL259917 Mu-type opioid receptor Cavia cutleri 153.5 ChEMBL 10.1016/j.bmc.2007.12.032 10.7270/Q2NZ88H7 18178091 Salvadori, S; Fiorini, S; Trapella, C; Porreca, F; Davis, P; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Balboni, G University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375298 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375298&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44451637 160854388 CHEMBL259917 ZINC29062678 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50863912 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCC1Cc2ccccc2C1 InChI=1S/C31H35N3O3/c1-19-11-26(35)12-20(2)27(19)16-28(32)31(37)34-18-25-10-6-5-9-24(25)15-29(34)30(36)33-17-21-13-22-7-3-4-8-23(22)14-21/h3-12,21,28-29,35H,13-18,32H2,1-2H3,(H,33,36)/t28-,29-/m0/s1 DDWRUPXWANOFLU-VMPREFPWSA-N 50375297 CHEMBL260127 Mu-type opioid receptor Cavia cutleri 28.41 ChEMBL 10.1016/j.bmc.2007.12.032 10.7270/Q2NZ88H7 18178091 Salvadori, S; Fiorini, S; Trapella, C; Porreca, F; Davis, P; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Balboni, G University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375297 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375297&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44451639 160854387 CHEMBL260127 ZINC29062691 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50863913 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCc1nc2ccccc2s1 InChI=1S/C29H30N4O3S/c1-17-11-21(34)12-18(2)22(17)14-23(30)29(36)33-16-20-8-4-3-7-19(20)13-25(33)28(35)31-15-27-32-24-9-5-6-10-26(24)37-27/h3-12,23,25,34H,13-16,30H2,1-2H3,(H,31,35)/t23-,25-/m0/s1 AWMRTINMSUQIBM-ZCYQVOJMSA-N 50375296 CHEMBL258704 Mu-type opioid receptor Cavia cutleri 129.1 ChEMBL 10.1016/j.bmc.2007.12.032 10.7270/Q2NZ88H7 18178091 Salvadori, S; Fiorini, S; Trapella, C; Porreca, F; Davis, P; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Balboni, G University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375296&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44451667 160854386 CHEMBL258704 ZINC29062903 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50863914 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCc1nc2ccccc2o1 InChI=1S/C29H30N4O4/c1-17-11-21(34)12-18(2)22(17)14-23(30)29(36)33-16-20-8-4-3-7-19(20)13-25(33)28(35)31-15-27-32-24-9-5-6-10-26(24)37-27/h3-12,23,25,34H,13-16,30H2,1-2H3,(H,31,35)/t23-,25-/m0/s1 JBEVAWMNEBELDV-ZCYQVOJMSA-N 50375299 CHEMBL258458 Mu-type opioid receptor Cavia cutleri 169.9 ChEMBL 10.1016/j.bmc.2007.12.032 10.7270/Q2NZ88H7 18178091 Salvadori, S; Fiorini, S; Trapella, C; Porreca, F; Davis, P; Sasaki, Y; Ambo, A; Marczak, ED; Lazarus, LH; Balboni, G University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375299&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44451689 160854389 CHEMBL258458 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50873463 Oc1ccc2C[C@H]3N(CC4CC4)CCC45C(Oc1c24)c1[nH]c2ccccc2c1CC35O InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1 WIYUZYBFCWCCQJ-XEWUMVRVSA-N 21864 (21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.0^{1,13}.0^{2,21}.0^{4,12}.0^{5,10}.0^{19,25}]pentacosa-4(12),5,7,9,15,17,19(25)-heptaene-2,16-diol::(8R)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol::NALTRINDOLE::[3H]-naltrindole Mu-type opioid receptor Cavia cutleri 12.7 ChEMBL 10.1021/jm701440h 10.7270/Q2PG1SN2 18637671 Sakami, S; Maeda, M; Kawai, K; Aoki, T; Kawamura, K; Fujii, H; Hasebe, K; Nakajima, M; Endo, T; Ueno, S; Ito, T; Kamei, J; Nagase, H Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21864&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3034754 49700969 ZINC62153992 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50873472 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2c4CCCCc4ccc2c1C[C@@]35O InChI=1S/C30H32N2O3/c33-22-10-8-18-13-23-30(34)14-21-20-9-7-17-3-1-2-4-19(17)25(20)31-26(21)28-29(30,24(18)27(22)35-28)11-12-32(23)15-16-5-6-16/h7-10,16,23,28,31,33-34H,1-6,11-15H2/t23-,28+,29+,30-/m1/s1 LZWGQEGAJVXMHU-UJLGHMMASA-N 50261791 (5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro-4,5-epoxy-6',7',8',9'-tetrahydro-1'H-benzo[g]indolo[2',3':6,7]morphinan-3,14-diol::CHEMBL469046 Mu-type opioid receptor Cavia cutleri 200 ChEMBL 10.1021/jm701440h 10.7270/Q2PG1SN2 18637671 Sakami, S; Maeda, M; Kawai, K; Aoki, T; Kawamura, K; Fujii, H; Hasebe, K; Nakajima, M; Endo, T; Ueno, S; Ito, T; Kamei, J; Nagase, H Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50261791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50261791&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15307413 104110667 CHEMBL469046 ZINC03808803 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50873473 COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1c(C[C@@]35O)c2cccc3CCCCn1c23 InChI=1S/C31H34N2O3/c1-35-23-11-10-20-15-24-31(34)16-22-21-7-4-6-19-5-2-3-13-33(26(19)21)27(22)29-30(31,25(20)28(23)36-29)12-14-32(24)17-18-8-9-18/h4,6-7,10-11,18,24,29,34H,2-3,5,8-9,12-17H2,1H3/t24-,29+,30+,31-/m1/s1 CNRASBPTPOATLU-CTZUUEIXSA-N 50261727 (5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro-4,5-epoxy-3-methoxy-4',5',6',7'-tetradehydro-azepino[3,2,1-hi]indolo[2',1':6,7]morphinan-14-ol::CHEMBL511773 Mu-type opioid receptor Cavia cutleri >3670 ChEMBL 10.1021/jm701440h 10.7270/Q2PG1SN2 18637671 Sakami, S; Maeda, M; Kawai, K; Aoki, T; Kawamura, K; Fujii, H; Hasebe, K; Nakajima, M; Endo, T; Ueno, S; Ito, T; Kamei, J; Nagase, H Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50261727 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50261727&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 24949689 104110633 CHEMBL511773 ZINC40403723 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50873474 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1c(C[C@@]35O)c2cccc3CCCCn1c23 InChI=1S/C30H32N2O3/c33-22-10-9-19-14-23-30(34)15-21-20-6-3-5-18-4-1-2-12-32(25(18)20)26(21)28-29(30,24(19)27(22)35-28)11-13-31(23)16-17-7-8-17/h3,5-6,9-10,17,23,28,33-34H,1-2,4,7-8,11-16H2/t23-,28+,29+,30-/m1/s1 FLBOXTBSDMMGNU-UJLGHMMASA-N 50261726 (5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro-4,5-epoxy-4',5',6',7'-tetradehydro-azepino[3,2,1-hi]indolo[2',1':6,7]morphinan-3,14-diol::CHEMBL469027 Mu-type opioid receptor Cavia cutleri 113 ChEMBL 10.1021/jm701440h 10.7270/Q2PG1SN2 18637671 Sakami, S; Maeda, M; Kawai, K; Aoki, T; Kawamura, K; Fujii, H; Hasebe, K; Nakajima, M; Endo, T; Ueno, S; Ito, T; Kamei, J; Nagase, H Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50261726 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50261726&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 24949687 104110632 CHEMBL469027 ZINC40896569 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50873475 COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1c(C[C@@]35O)c2cccc3CCCn1c23 InChI=1S/C30H32N2O3/c1-34-22-10-9-19-14-23-30(33)15-21-20-6-2-4-18-5-3-12-32(25(18)20)26(21)28-29(30,24(19)27(22)35-28)11-13-31(23)16-17-7-8-17/h2,4,6,9-10,17,23,28,33H,3,5,7-8,11-16H2,1H3/t23-,28+,29+,30-/m1/s1 JUQKSLOQCIZKLV-UJLGHMMASA-N 50245093 (5R,9R,13S,14S)-17-cyclopropylmethyl-6,7-didehydro-4,5-epoxy-5',6'-dihydro-3-methoxy-4'H-pyrrolo[3,2,1-ij]quinolino[2',1':6,7]morphinan-14-ol methanesulfonate::CHEMBL504916 Mu-type opioid receptor Cavia cutleri >3670 ChEMBL 10.1021/jm701440h 10.7270/Q2PG1SN2 18637671 Sakami, S; Maeda, M; Kawai, K; Aoki, T; Kawamura, K; Fujii, H; Hasebe, K; Nakajima, M; Endo, T; Ueno, S; Ito, T; Kamei, J; Nagase, H Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245093&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 24949685 104100952 CHEMBL504916 ZINC40834290 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50873476 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1c(C[C@@]35O)c2cccc3CCCn1c23 InChI=1S/C29H30N2O3/c32-21-9-8-18-13-22-29(33)14-20-19-5-1-3-17-4-2-11-31(24(17)19)25(20)27-28(29,23(18)26(21)34-27)10-12-30(22)15-16-6-7-16/h1,3,5,8-9,16,22,27,32-33H,2,4,6-7,10-15H2/t22-,27+,28+,29-/m1/s1 BANOAHCDQRCVAB-KZNIJNHCSA-N 50244419 (4bS,8R,8aS,16bR)-7-(cyclopropylmethyl)-5,6,7,8,8a,9,13,14,15,16b-decahydro-4,8-methanobenzofuro[2,3-a]dipyrido[4,3-b:3',2',1'-jk]carbazole-1,8a-diol::(5R,9R,13S,14S)-17-cyclopropylmethyl-6,7-didehydro-4,5-epoxy-5',6'-dihydro-4'H-pyrrolo[3,2,1-ij]quinolino[2',1':6,7]morphinan-3,14-diol::CHEMBL520557 Mu-type opioid receptor Cavia cutleri 60.6 ChEMBL 10.1021/jm701440h 10.7270/Q2PG1SN2 18637671 Sakami, S; Maeda, M; Kawai, K; Aoki, T; Kawamura, K; Fujii, H; Hasebe, K; Nakajima, M; Endo, T; Ueno, S; Ito, T; Kamei, J; Nagase, H Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50244419 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50244419&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 24949683 104100449 CHEMBL520557 ZINC42835763 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50873477 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1c(C[C@@]35O)c2cccc3CCn1c23 InChI=1S/C28H28N2O3/c31-20-7-6-17-12-21-28(32)13-19-18-3-1-2-16-8-10-30(23(16)18)24(19)26-27(28,22(17)25(20)33-26)9-11-29(21)14-15-4-5-15/h1-3,6-7,15,21,26,31-32H,4-5,8-14H2/t21-,26+,27+,28-/m1/s1 DBVSPUURNDDMFE-OZBXUNDUSA-N 50262557 (5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro-4,5-epoxy-1',2'-dihydropyrrolo[3,2,1-hi]indolo[4',5':6,7]morphinan-3,14-diol::CHEMBL476540 Mu-type opioid receptor Cavia cutleri 23.2 ChEMBL 10.1021/jm701440h 10.7270/Q2PG1SN2 18637671 Sakami, S; Maeda, M; Kawai, K; Aoki, T; Kawamura, K; Fujii, H; Hasebe, K; Nakajima, M; Endo, T; Ueno, S; Ito, T; Kamei, J; Nagase, H Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50262557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50262557&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 24949532 104111208 CHEMBL476540 ZINC03827348 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50873478 CCn1c2[C@@H]3Oc4c5c(C[C@H]6N(CC7CC7)CC[C@@]35[C@@]6(O)Cc2c2cccc(C)c12)ccc4OC InChI=1S/C30H34N2O3/c1-4-32-25-17(2)6-5-7-20(25)21-15-30(33)23-14-19-10-11-22(34-3)27-24(19)29(30,28(35-27)26(21)32)12-13-31(23)16-18-8-9-18/h5-7,10-11,18,23,28,33H,4,8-9,12-16H2,1-3H3/t23-,28+,29+,30-/m1/s1 RKOLBCBUMFTVRH-UJLGHMMASA-N 50262556 (5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro-4,5-epoxy-1'-ethyl-3-methoxy-7'-methyl-indolo[2',3':6,7]morphinan-14-ol::CHEMBL514366 Mu-type opioid receptor Cavia cutleri >3670 ChEMBL 10.1021/jm701440h 10.7270/Q2PG1SN2 18637671 Sakami, S; Maeda, M; Kawai, K; Aoki, T; Kawamura, K; Fujii, H; Hasebe, K; Nakajima, M; Endo, T; Ueno, S; Ito, T; Kamei, J; Nagase, H Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50262556 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50262556&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 24949529 104111207 CHEMBL514366 ZINC40918610 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50873482 Oc1ccc2C[C@H]3N(CC4CC4)CCC45C(Oc1c24)c1[nH]c2ccccc2c1CC35O InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1 WIYUZYBFCWCCQJ-XEWUMVRVSA-N 21864 (21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.0^{1,13}.0^{2,21}.0^{4,12}.0^{5,10}.0^{19,25}]pentacosa-4(12),5,7,9,15,17,19(25)-heptaene-2,16-diol::(8R)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol::NALTRINDOLE::[3H]-naltrindole Mu-type opioid receptor Cavia cutleri 27 ChEMBL 10.1021/jm701440h 10.7270/Q2PG1SN2 18637671 Sakami, S; Maeda, M; Kawai, K; Aoki, T; Kawamura, K; Fujii, H; Hasebe, K; Nakajima, M; Endo, T; Ueno, S; Ito, T; Kamei, J; Nagase, H Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21864&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3034754 49700969 ZINC62153992 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50873484 COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2ccccc2c1C[C@@]35O InChI=1S/C27H28N2O3/c1-31-20-9-8-16-12-21-27(30)13-18-17-4-2-3-5-19(17)28-23(18)25-26(27,22(16)24(20)32-25)10-11-29(21)14-15-6-7-15/h2-5,8-9,15,21,25,28,30H,6-7,10-14H2,1H3/t21-,25+,26+,27-/m1/s1 HKUIBYDTKWHKJU-NVSKSXHLSA-N 50262499 (5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro-4,5-epoxy-3-methoxy-indolo[2',3':6,7]morphinan-14-ol::22-cyclopropylmethyl-16-methoxy-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaen-2-ol(HCl1.5H2O)::CHEMBL514693 Mu-type opioid receptor Cavia cutleri 2510 ChEMBL 10.1021/jm701440h 10.7270/Q2PG1SN2 18637671 Sakami, S; Maeda, M; Kawai, K; Aoki, T; Kawamura, K; Fujii, H; Hasebe, K; Nakajima, M; Endo, T; Ueno, S; Ito, T; Kamei, J; Nagase, H Toray Industries Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50262499 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50262499&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44578135 104111161 CHEMBL514693 ZINC03808807 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50865315 Cc1cc(O)cc(O)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(O)=O InChI=1S/C43H49N5O9/c1-27-20-32(49)23-38(50)33(27)24-34(44)41(53)48-25-31-17-9-8-16-30(31)22-37(48)40(52)47-36(21-28-12-4-2-5-13-28)39(51)46-35(42(54)55)18-10-11-19-45-43(56)57-26-29-14-6-3-7-15-29/h2-9,12-17,20,23,34-37,49-50H,10-11,18-19,21-22,24-26,44H2,1H3,(H,45,56)(H,46,51)(H,47,52)(H,54,55)/t34-,35-,36-,37+/m0/s1 SGYUWRWFTZOXFP-MYOMABOUSA-N 50375695 CHEMBL270984 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/jm7014765 10.7270/Q24T6K7K 18311909 Ryu, EK; Wu, Z; Chen, K; Lazarus, LH; Marczak, ED; Sasaki, Y; Ambo, A; Salvadori, S; Ren, C; Zhao, H; Balboni, G; Chen, X Stanford University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375695 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375695&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44457210 160854785 CHEMBL270984 ZINC95608099 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50865320 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@@H]1C(=O)NCCCC[C@H](NC(=O)c1ccc(F)cc1)C(O)=O InChI=1S/C34H39FN4O6/c1-20-15-26(40)16-21(2)27(20)18-28(36)33(43)39-19-24-8-4-3-7-23(24)17-30(39)32(42)37-14-6-5-9-29(34(44)45)38-31(41)22-10-12-25(35)13-11-22/h3-4,7-8,10-13,15-16,28-30,40H,5-6,9,14,17-19,36H2,1-2H3,(H,37,42)(H,38,41)(H,44,45)/t28-,29-,30+/m0/s1 DDQFJPGOPGFERI-OIFRRMEBSA-N 50375694 CHEMBL244265 Mu-type opioid receptor Cavia cutleri 1916 ChEMBL 10.1021/jm7014765 10.7270/Q24T6K7K 18311909 Ryu, EK; Wu, Z; Chen, K; Lazarus, LH; Marczak, ED; Sasaki, Y; Ambo, A; Salvadori, S; Ren, C; Zhao, H; Balboni, G; Chen, X Stanford University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375694 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375694&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44457205 160854784 CHEMBL244265 ZINC29134389 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50865321 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCNC(=O)c1ccc(F)cc1)C(O)=O InChI=1S/C43H48FN5O7/c1-26-20-33(50)21-27(2)34(26)24-35(45)42(54)49-25-31-13-7-6-12-30(31)23-38(49)41(53)48-37(22-28-10-4-3-5-11-28)40(52)47-36(43(55)56)14-8-9-19-46-39(51)29-15-17-32(44)18-16-29/h3-7,10-13,15-18,20-21,35-38,50H,8-9,14,19,22-25,45H2,1-2H3,(H,46,51)(H,47,52)(H,48,53)(H,55,56)/t35-,36-,37-,38+/m0/s1 WCPSDLOTJZKOSW-IZBQCXFTSA-N 50375696 CHEMBL269842 Mu-type opioid receptor Cavia cutleri 50.6 ChEMBL 10.1021/jm7014765 10.7270/Q24T6K7K 18311909 Ryu, EK; Wu, Z; Chen, K; Lazarus, LH; Marczak, ED; Sasaki, Y; Ambo, A; Salvadori, S; Ren, C; Zhao, H; Balboni, G; Chen, X Stanford University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375696 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375696&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44457204 160854786 CHEMBL269842 ZINC95608040 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50882052 O=C1N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](Cc2ccccc2)C(=O)N2CCC[C@H]12 InChI=1S/C34H35N5O4/c40-31-27(18-22-10-3-1-4-11-22)37-33(42)30-16-9-17-39(30)34(43)29(19-23-12-5-2-6-13-23)38-32(41)28(36-31)20-24-21-35-26-15-8-7-14-25(24)26/h1-8,10-15,21,27-30,35H,9,16-20H2,(H,36,40)(H,37,42)(H,38,41)/t27-,28-,29-,30+/m0/s1 GIZJWWQFOGQPRY-GCXHJFECSA-N 50268462 CHEMBL506616::c[L-Phe-D-pro-L-Phe-L-trp] Mu-type opioid receptor Cavia cutleri 260 ChEMBL 10.1016/j.bmcl.2009.04.105 10.7270/Q2HT2Q8K 19464172 Dolle, RE; Michaut, M; Martinez-Teipel, B; Seida, PR; Ajello, CW; Muller, AL; DeHaven, RN; Carroll, PJ Adolor Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50268462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50268462&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44583372 104114853 CHEMBL506616 ZINC03989600 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50879649 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35OC(=O)\C=C\c1ccccc1 InChI=1S/C29H29NO5/c31-21-10-9-20-16-23-29(35-24(33)11-8-18-4-2-1-3-5-18)13-12-22(32)27-28(29,25(20)26(21)34-27)14-15-30(23)17-19-6-7-19/h1-5,8-11,19,23,27,31H,6-7,12-17H2/b11-8+/t23-,27+,28+,29-/m1/s1 JGNAFYMWPWRALJ-QGCOSWPOSA-N 50248968 14beta-Cinnamoyloxy-N-cyclopropylmethyl-7,8-dihydronormorphinone::CHEMBL473206 Mu-type opioid receptor Cavia cutleri 0.400000 ChEMBL 10.1021/jm8012272 10.7270/Q2G44R6N 19253983 Moynihan, H; Jales, AR; Greedy, BM; Rennison, D; Broadbear, JH; Purington, L; Traynor, JR; Woods, JH; Lewis, JW; Husbands, SM University of Bath http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50248968 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50248968&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25257198 104103419 CHEMBL473206 C06357 ZINC40913485 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50879652 Cc1ccc(\C=C\C(=O)O[C@]23CCC(=O)[C@@H]4Oc5c6c(C[C@H]2N(CC2CC2)CC[C@@]346)ccc5O)cc1 InChI=1S/C30H31NO5/c1-18-2-4-19(5-3-18)8-11-25(34)36-30-13-12-23(33)28-29(30)14-15-31(17-20-6-7-20)24(30)16-21-9-10-22(32)27(35-28)26(21)29/h2-5,8-11,20,24,28,32H,6-7,12-17H2,1H3/b11-8+/t24-,28+,29+,30-/m1/s1 NMTMBZUBWPVSPH-SHEAVXILSA-N 50248990 14beta-(4-Methylcinnamoyloxy)-N-cyclopropylmethyl-7,8-dihydronormorphinone::CHEMBL474641 Mu-type opioid receptor Cavia cutleri 3.3 ChEMBL 10.1021/jm8012272 10.7270/Q2G44R6N 19253983 Moynihan, H; Jales, AR; Greedy, BM; Rennison, D; Broadbear, JH; Purington, L; Traynor, JR; Woods, JH; Lewis, JW; Husbands, SM University of Bath http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50248990 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50248990&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25257200 104103427 CHEMBL474641 ZINC40409112 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50879653 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35OC(=O)\C=C\c1ccc(Cl)cc1 InChI=1S/C29H28ClNO5/c30-20-7-3-17(4-8-20)5-10-24(34)36-29-12-11-22(33)27-28(29)13-14-31(16-18-1-2-18)23(29)15-19-6-9-21(32)26(35-27)25(19)28/h3-10,18,23,27,32H,1-2,11-16H2/b10-5+/t23-,27+,28+,29-/m1/s1 SHGIEUUYOPTYHQ-DNIKMYEQSA-N 50248969 14beta-(4-Chlorocinnamoyloxy)-N-cyclopropylmethyl-7,8-dihydronormorphinone::CHEMBL514927 Mu-type opioid receptor Cavia cutleri 1.3 ChEMBL 10.1021/jm8012272 10.7270/Q2G44R6N 19253983 Moynihan, H; Jales, AR; Greedy, BM; Rennison, D; Broadbear, JH; Purington, L; Traynor, JR; Woods, JH; Lewis, JW; Husbands, SM University of Bath http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50248969 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50248969&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25257199 104103420 CHEMBL514927 ZINC40899355 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50876298 CCC12CCN(CC3CC3)C(C1C)C(=O)c1ccc(O)cc21 InChI=1S/C19H25NO2/c1-3-19-8-9-20(11-13-4-5-13)17(12(19)2)18(22)15-7-6-14(21)10-16(15)19/h6-7,10,12-13,17,21H,3-5,8-9,11H2,1-2H3 SEJUQQOPVAUETF-UHFFFAOYSA-N 50045114 3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::CHEMBL55033::EKC Mu-type opioid receptor Cavia cutleri 0.780000 ChEMBL 10.1016/j.bmcl.2008.10.134 10.7270/Q2RX9D1K 19027293 Wentland, MP; Lou, R; Lu, Q; Bu, Y; VanAlstine, MA; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045114 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045114&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 4491166 103976212 CHEMBL55033 ZINC04102216 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50876300 CCC12CCN(CC3CC3)C(C1C)C(=O)c1ccc(cc21)C(N)=O InChI=1S/C20H26N2O2/c1-3-20-8-9-22(11-13-4-5-13)17(12(20)2)18(23)15-7-6-14(19(21)24)10-16(15)20/h6-7,10,12-13,17H,3-5,8-9,11H2,1-2H3,(H2,21,24) NBEPKKBOGWVFFT-UHFFFAOYSA-N 50254563 3-Cyclopropylmethyl-6-ethyl-11-methyl-1-oxo-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid amide::CHEMBL461229 Mu-type opioid receptor Cavia cutleri 1.2 ChEMBL 10.1016/j.bmcl.2008.10.134 10.7270/Q2RX9D1K 19027293 Wentland, MP; Lou, R; Lu, Q; Bu, Y; VanAlstine, MA; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50254563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50254563&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44570065 104106759 CHEMBL461229 ZINC13490123 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50876302 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 0.880000 ChEMBL 10.1016/j.bmcl.2008.10.134 10.7270/Q2RX9D1K 19027293 Wentland, MP; Lou, R; Lu, Q; Bu, Y; VanAlstine, MA; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50876304 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5C(N)=O InChI=1S/C18H20N2O3/c1-20-7-6-18-11-4-5-13(21)16(18)23-15-10(17(19)22)3-2-9(14(15)18)8-12(11)20/h2-5,11-13,16,21H,6-8H2,1H3,(H2,19,22)/t11-,12+,13-,16-,18-/m0/s1 IBOHPBGICFUISW-UAXVXCKYSA-N 50254564 (1S,5R,13R,14S,17R)-14-hydroxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7,9,11(18),15-tetraene-10-carboxamide::CHEMBL505011 Mu-type opioid receptor Cavia cutleri 34 ChEMBL 10.1016/j.bmcl.2008.10.134 10.7270/Q2RX9D1K 19027293 Wentland, MP; Lou, R; Lu, Q; Bu, Y; VanAlstine, MA; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50254564 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50254564&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10086867 104106760 CHEMBL505011 ZINC29411258 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50876339 C[C@H]1[C@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2C[C@@H]1CCCO1 InChI=1S/C19H27NO2/c1-13-18-10-14-5-6-15(21)11-17(14)19(13,2)7-8-20(18)12-16-4-3-9-22-16/h5-6,11,13,16,18,21H,3-4,7-10,12H2,1-2H3/t13-,16-,18+,19-/m0/s1 NLKLXMMOJZHSCB-IVJVFBROSA-N 50007102 6,11-Dimethyl-3-(tetrahydro-furan-2-ylmethyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL79470::MR-2034 Mu-type opioid receptor Cavia cutleri 0.190000 ChEMBL 10.1016/j.bmcl.2008.10.134 10.7270/Q2RX9D1K 19027293 Wentland, MP; Lou, R; Lu, Q; Bu, Y; VanAlstine, MA; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007102 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007102&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 68196155 103920385 CHEMBL79470 ZINC13493451 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50876344 C[C@@H]1[C@@H]2Cc3ccc(cc3[C@@]1(C)CCN2C[C@@H]1CCCO1)C(N)=O InChI=1S/C20H28N2O2/c1-13-18-11-14-5-6-15(19(21)23)10-17(14)20(13,2)7-8-22(18)12-16-4-3-9-24-16/h5-6,10,13,16,18H,3-4,7-9,11-12H2,1-2H3,(H2,21,23)/t13-,16+,18+,20+/m1/s1 OWRBBFHZDDJXIW-BPODSCFKSA-N 50254568 (2S,6S,11S)-6,11-Dimethyl-3-[(S)-1-(tetrahydro-furan-2-yl)methyl]-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid amide::CHEMBL517166 Mu-type opioid receptor Cavia cutleri 0.052000 ChEMBL 10.1016/j.bmcl.2008.10.134 10.7270/Q2RX9D1K 19027293 Wentland, MP; Lou, R; Lu, Q; Bu, Y; VanAlstine, MA; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50254568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50254568&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44570068 104106764 CHEMBL517166 ZINC40873138 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50876348 C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2C[C@H]1CCCO1 InChI=1S/C19H27NO2/c1-13-18-10-14-5-6-15(21)11-17(14)19(13,2)7-8-20(18)12-16-4-3-9-22-16/h5-6,11,13,16,18,21H,3-4,7-10,12H2,1-2H3/t13-,16-,18+,19+/m1/s1 NLKLXMMOJZHSCB-OLQIXAPSSA-N 50254569 (2S,6S,11S)-6,11-Dimethyl-3-[(R)-1-(tetrahydro-furan-2-yl)methyl]-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL464071 Mu-type opioid receptor Cavia cutleri 4 ChEMBL 10.1016/j.bmcl.2008.10.134 10.7270/Q2RX9D1K 19027293 Wentland, MP; Lou, R; Lu, Q; Bu, Y; VanAlstine, MA; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50254569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50254569&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44570069 104106765 CHEMBL464071 ZINC13823424 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50876351 C[C@@H]1[C@@H]2Cc3ccc(cc3[C@@]1(C)CCN2C[C@H]1CCCO1)C(N)=O InChI=1S/C20H28N2O2/c1-13-18-11-14-5-6-15(19(21)23)10-17(14)20(13,2)7-8-22(18)12-16-4-3-9-24-16/h5-6,10,13,16,18H,3-4,7-9,11-12H2,1-2H3,(H2,21,23)/t13-,16-,18+,20+/m1/s1 OWRBBFHZDDJXIW-GNYRAKODSA-N 50254509 (2S,6S,11S)-6,11-Dimethyl-3-[(R)-1-(tetrahydro-furan-2-yl)methyl]-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid amide::CHEMBL459746 Mu-type opioid receptor Cavia cutleri 2.9 ChEMBL 10.1016/j.bmcl.2008.10.134 10.7270/Q2RX9D1K 19027293 Wentland, MP; Lou, R; Lu, Q; Bu, Y; VanAlstine, MA; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50254509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50254509&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44570027 104106714 CHEMBL459746 ZINC40860871 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50876361 CC1C2N(CC3CC3)CCC1(C)c1cc(ccc1C2=O)C(N)=O InChI=1S/C19H24N2O2/c1-11-16-17(22)14-6-5-13(18(20)23)9-15(14)19(11,2)7-8-21(16)10-12-3-4-12/h5-6,9,11-12,16H,3-4,7-8,10H2,1-2H3,(H2,20,23) UZBPHRWPBOWFLU-UHFFFAOYSA-N 50254510 3-Cyclopropylmethyl-6,11-dimethyl-1-oxo-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid amide::CHEMBL511691 Mu-type opioid receptor Cavia cutleri 1.4 ChEMBL 10.1016/j.bmcl.2008.10.134 10.7270/Q2RX9D1K 19027293 Wentland, MP; Lou, R; Lu, Q; Bu, Y; VanAlstine, MA; Cohen, DJ; Bidlack, JM Rensselaer Polytechnic Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50254510 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50254510&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44570028 104106715 CHEMBL511691 ZINC40392770 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50878805 CC(C)CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)CCC4=O)ccc5O InChI=1S/C20H25NO4/c1-11(2)10-21-8-7-19-16-12-3-4-13(22)17(16)25-18(19)14(23)5-6-20(19,24)15(21)9-12/h3-4,11,15,18,22,24H,5-10H2,1-2H3/t15-,18+,19+,20-/m1/s1 OEQLILQNMUXCHV-XFWGSAIBSA-N 50264867 CHEMBL490418::N-isobutylnoroxymorphone Mu-type opioid receptor Cavia cutleri 5.57 ChEMBL 10.1016/j.bmcl.2008.08.019 10.7270/Q2J38TH9 18755589 Fujii, H; Osa, Y; Ishihara, M; Hanamura, S; Nemoto, T; Nakajima, M; Hasebe, K; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264867&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25178033 104112713 CHEMBL490418 ZINC40950353 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50883825 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C46H56N10O10/c1-27(51-43(63)35(47)21-31-13-17-33(57)18-14-31)41(61)49-25-39(59)53-37(23-29-9-5-3-6-10-29)45(65)55-56-46(66)38(24-30-11-7-4-8-12-30)54-40(60)26-50-42(62)28(2)52-44(64)36(48)22-32-15-19-34(58)20-16-32/h3-20,27-28,35-38,57-58H,21-26,47-48H2,1-2H3,(H,49,61)(H,50,62)(H,51,63)(H,52,64)(H,53,59)(H,54,60)(H,55,65)(H,56,66)/t27-,28-,35+,36+,37+,38+/m1/s1 DESSEGDLRYOPTJ-VRANXALZSA-N 21014 (2S)-2-amino-N-[(1R)-1-[({[(1S)-1-{N'-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanoyl]hydrazinecarbonyl}-2-phenylethyl]carbamoyl}methyl)carbamoyl]ethyl]-3-(4-hydroxyphenyl)propanamide::(Tyr-Ala-Gly-Phe-NH2)2::Biphalin::CHEMBL200199::bis(Tyr-Ala-Gly-PheNH2)hydrazide::enkephalin dimer Mu-type opioid receptor Cavia cutleri 8.8 ChEMBL 10.1021/jm900473p 10.7270/Q2MC90ZZ 20560643 Yamamoto, T; Nair, P; Jacobsen, NE; Vagner, J; Kulkarni, V; Davis, P; Ma, SW; Navratilova, E; Yamamura, HI; Vanderah, TW; Porreca, F; Lai, J; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21014&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5487663 49689087 CHEMBL200199 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50882711 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]4(CC(=O)[C@H]5CC[C@@]34O5)c2c1 InChI=1S/C21H25NO3/c23-15-4-3-14-9-19-21-6-5-18(25-21)17(24)11-20(21,16(14)10-15)7-8-22(19)12-13-1-2-13/h3-4,10,13,18-19,23H,1-2,5-9,11-12H2/t18-,19-,20-,21-/m1/s1 DFCRDTHYBCKRGA-XRXFAXGQSA-N 50277470 (1R,9R,10S,13R)-18-(cyclopropylmethyl)-4-hydroxy-19-oxa-18-azapentacyclo[7.6.3.1^{10,13}.0^{1,10}.0^{2,7}]nonadeca-2(7),3,5-trien-14-one::CHEMBL474296 Mu-type opioid receptor Cavia cutleri 0.397 ChEMBL 10.1016/j.bmcl.2009.03.068 10.7270/Q2C24XBW 19349178 Watanabe, A; Fujii, H; Nakajima, M; Hasebe, K; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50277470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50277470&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44591475 104120063 CHEMBL474296 ZINC40914832 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50882715 OC[C@]12CC[C@@]3(O1)[C@H]1Cc4ccc(O)cc4[C@]3(C2)CCN1CC1CC1 InChI=1S/C21H27NO3/c23-13-19-5-6-21(25-19)18-9-15-3-4-16(24)10-17(15)20(21,12-19)7-8-22(18)11-14-1-2-14/h3-4,10,14,18,23-24H,1-2,5-9,11-13H2/t18-,19-,20-,21-/m1/s1 KZPYCWJXCIGRQW-XRXFAXGQSA-N 50277471 (1R,9R,10S,13R)-17-(cyclopropylmethyl)-13-(hydroxymethyl)-18-oxa-17-azapentacyclo[7.5.3.1^{10,13}.0^{1,10}.0^{2,7}]octadeca-2(7),3,5-trien-4-ol::CHEMBL474497 Mu-type opioid receptor Cavia cutleri 0.145 ChEMBL 10.1016/j.bmcl.2009.03.068 10.7270/Q2C24XBW 19349178 Watanabe, A; Fujii, H; Nakajima, M; Hasebe, K; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50277471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50277471&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44591476 104120064 CHEMBL474497 ZINC40913923 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50883857 CCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C64H80F6N10O15/c1-5-6-15-45(77-60(92)47(25-35-12-8-7-9-13-35)76-51(83)30-74-55(87)34(4)75-56(88)43(71)24-36-17-19-41(82)20-18-36)58(90)80-49(32-94-62-54(86)53(85)52(84)50(31-81)95-62)61(93)78-46(21-33(2)3)59(91)79-48(26-38-29-72-44-16-11-10-14-42(38)44)57(89)73-28-37-22-39(63(65,66)67)27-40(23-37)64(68,69)70/h7-14,16-20,22-23,27,29,33-34,43,45-50,52-54,62,72,81-82,84-86H,5-6,15,21,24-26,28,30-32,71H2,1-4H3,(H,73,89)(H,74,87)(H,75,88)(H,76,83)(H,77,92)(H,78,93)(H,79,91)(H,80,90)/t34-,43+,45+,46+,47+,48+,49+,50-,52-,53+,54-,62-/m1/s1 BLKHBPBPTMODSH-RAWAAWEYSA-N 50295071 (S)-2-((S)-2-(2-((R)-2-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)propanamido)acetamido)-3-phenylpropanamido)-N-((S)-1-((S)-1-((S)-1-(3,5-bis(trifluoromethyl)benzylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-4-methyl-1-oxopentan-2-ylamino)-1-oxo-3-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)propan-2-yl)hexanamide::CHEMBL538131 Mu-type opioid receptor Cavia cutleri 250 ChEMBL 10.1021/jm900473p 10.7270/Q2MC90ZZ 20560643 Yamamoto, T; Nair, P; Jacobsen, NE; Vagner, J; Kulkarni, V; Davis, P; Ma, SW; Navratilova, E; Yamamura, HI; Vanderah, TW; Porreca, F; Lai, J; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295071&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44233184 104136602 CHEMBL538131 C03400 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50883858 CCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C63H76F6N10O15/c1-3-4-14-44(76-57(89)45(25-34-11-6-5-7-12-34)75-50(82)30-73-54(86)33(2)74-55(87)42(70)24-35-17-19-40(81)20-18-35)60(92)79-21-10-16-48(79)59(91)78-47(32-93-61-53(85)52(84)51(83)49(31-80)94-61)58(90)77-46(26-37-29-71-43-15-9-8-13-41(37)43)56(88)72-28-36-22-38(62(64,65)66)27-39(23-36)63(67,68)69/h5-9,11-13,15,17-20,22-23,27,29,33,42,44-49,51-53,61,71,80-81,83-85H,3-4,10,14,16,21,24-26,28,30-32,70H2,1-2H3,(H,72,88)(H,73,86)(H,74,87)(H,75,82)(H,76,89)(H,77,90)(H,78,91)/t33-,42+,44+,45+,46+,47+,48+,49-,51-,52+,53-,61-/m1/s1 IPMMBNAOLDMKAM-PYIJLGDTSA-N 50295072 (S)-1-((2S,5S,11R,14S)-14-amino-5-benzyl-2-butyl-15-(4-hydroxyphenyl)-11-methyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane)-N-((S)-1-((S)-1-(3,5-bis(trifluoromethyl)benzylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-1-oxo-3-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)propan-2-yl)pyrrolidine-2-carboxamide::CHEMBL539193 Mu-type opioid receptor Cavia cutleri 520 ChEMBL 10.1021/jm900473p 10.7270/Q2MC90ZZ 20560643 Yamamoto, T; Nair, P; Jacobsen, NE; Vagner, J; Kulkarni, V; Davis, P; Ma, SW; Navratilova, E; Yamamura, HI; Vanderah, TW; Porreca, F; Lai, J; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295072&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44233185 104136603 CHEMBL539193 C03400 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50883859 CCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO[C@@H]1O[C@H](CC)[C@@H](O)[C@H](O)[C@H]1O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C70H89F6N11O15/c1-6-8-18-49(83-64(97)51(30-39-15-10-9-11-16-39)82-56(89)35-80-60(93)38(5)81-61(94)47(77)29-40-21-23-45(88)24-22-40)67(100)87-25-14-20-54(87)66(99)85-50(26-37(3)4)63(96)86-53(36-101-68-59(92)58(91)57(90)55(7-2)102-68)65(98)84-52(31-42-34-78-48-19-13-12-17-46(42)48)62(95)79-33-41-27-43(69(71,72)73)32-44(28-41)70(74,75)76/h9-13,15-17,19,21-24,27-28,32,34,37-38,47,49-55,57-59,68,78,88,90-92H,6-8,14,18,20,25-26,29-31,33,35-36,77H2,1-5H3,(H,79,95)(H,80,93)(H,81,94)(H,82,89)(H,83,97)(H,84,98)(H,85,99)(H,86,96)/t38-,47+,49+,50+,51+,52+,53+,54+,55-,57-,58+,59-,68-/m1/s1 ACFPRWCERXMNGY-SVJKDRGJSA-N 50295067 (S)-1-((2S,5S,11R,14S)-14-amino-5-benzyl-2-butyl-15-(4-hydroxyphenyl)-11-methyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane)-N-((S)-1-((S)-1-((S)-1-(3,5-bis(trifluoromethyl)benzylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-3-((2R,3R,4S,5S,6R)-6-ethyl-3,4,5-trihydroxytetrahydro-2H-pyran-2-yloxy)-1-oxopropan-2-ylamino)-4-methyl-1-oxopentan-2-yl)pyrrolidine-2-carboxamide::CHEMBL556537 Mu-type opioid receptor Cavia cutleri 670 ChEMBL 10.1021/jm900473p 10.7270/Q2MC90ZZ 20560643 Yamamoto, T; Nair, P; Jacobsen, NE; Vagner, J; Kulkarni, V; Davis, P; Ma, SW; Navratilova, E; Yamamura, HI; Vanderah, TW; Porreca, F; Lai, J; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295067&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 45271306 104136598 CHEMBL556537 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50883860 CCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C60H72F6N10O9/c1-5-6-16-46(73-56(83)48(28-36-13-8-7-9-14-36)72-51(78)33-70-52(79)35(4)71-53(80)44(67)27-37-19-21-42(77)22-20-37)58(85)76-23-12-18-50(76)57(84)75-47(24-34(2)3)55(82)74-49(29-39-32-68-45-17-11-10-15-43(39)45)54(81)69-31-38-25-40(59(61,62)63)30-41(26-38)60(64,65)66/h7-11,13-15,17,19-22,25-26,30,32,34-35,44,46-50,68,77H,5-6,12,16,18,23-24,27-29,31,33,67H2,1-4H3,(H,69,81)(H,70,79)(H,71,80)(H,72,78)(H,73,83)(H,74,82)(H,75,84)/t35-,44+,46+,47+,48+,49+,50+/m1/s1 ADVXLVRKUFJJTA-CYLPJFJESA-N 50295069 (S)-1-((2S,5S,11R,14S)-14-amino-5-benzyl-2-butyl-15-(4-hydroxyphenyl)-11-methyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane)-N-((S)-1-((S)-1-(3,5-bis(trifluoromethyl)benzylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-4-methyl-1-oxopentan-2-yl)pyrrolidine-2-carboxamide::CHEMBL557188 Mu-type opioid receptor Cavia cutleri 460 ChEMBL 10.1021/jm900473p 10.7270/Q2MC90ZZ 20560643 Yamamoto, T; Nair, P; Jacobsen, NE; Vagner, J; Kulkarni, V; Davis, P; Ma, SW; Navratilova, E; Yamamura, HI; Vanderah, TW; Porreca, F; Lai, J; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295069 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295069&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44177145 104136600 CHEMBL557188 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50883861 CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C63H76F6N10O15/c1-32(2)20-44(57(89)76-46(25-37-28-71-43-13-8-7-12-41(37)43)56(88)72-27-36-21-38(62(64,65)66)26-39(22-36)63(67,68)69)77-59(91)48-14-9-19-79(48)60(92)47(31-93-61-53(85)52(84)51(83)49(30-80)94-61)78-58(90)45(24-34-10-5-4-6-11-34)75-50(82)29-73-54(86)33(3)74-55(87)42(70)23-35-15-17-40(81)18-16-35/h4-8,10-13,15-18,21-22,26,28,32-33,42,44-49,51-53,61,71,80-81,83-85H,9,14,19-20,23-25,27,29-31,70H2,1-3H3,(H,72,88)(H,73,86)(H,74,87)(H,75,82)(H,76,89)(H,77,91)(H,78,90)/t33-,42+,44+,45+,46+,47+,48+,49-,51-,52+,53-,61-/m1/s1 WMTKHCQGJKXVST-PYIJLGDTSA-N 50295070 (S)-1-((2S,5S,11R,14S)-14-amino-5-benzyl-15-(4-hydroxyphenyl)-11-methyl-4,7,10,13-tetraoxo-2-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)methyl)-3,6,9,12-tetraazapentadecane)-N-((S)-1-((S)-1-(3,5-bis(trifluoromethyl)benzylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-4-methyl-1-oxopentan-2-yl)pyrrolidine-2-carboxamide::CHEMBL555504 Mu-type opioid receptor Cavia cutleri 1900 ChEMBL 10.1021/jm900473p 10.7270/Q2MC90ZZ 20560643 Yamamoto, T; Nair, P; Jacobsen, NE; Vagner, J; Kulkarni, V; Davis, P; Ma, SW; Navratilova, E; Yamamura, HI; Vanderah, TW; Porreca, F; Lai, J; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295070 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295070&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44233410 104136601 CHEMBL555504 C03400 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50907198 CN([C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45)C(=O)\C=C\c1ccco1 InChI=1S/C28H32N2O5/c1-29(23(32)9-7-19-3-2-14-34-19)20-10-11-28(33)22-15-18-6-8-21(31)25-24(18)27(28,26(20)35-25)12-13-30(22)16-17-4-5-17/h2-3,6-9,14,17,20,22,26,31,33H,4-5,10-13,15-16H2,1H3/b9-7+/t20-,22-,26+,27+,28-/m1/s1 VJGYEDILSGGSMK-NUINQRJCSA-N 50274257 (2E)-N-[(1S,5R,13R,14R,17S)-4-(cyclopropylmethyl)-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7,9,11(18)-trien-14-yl]-3-(furan-2-yl)-N-methylprop-2-enamide::(2E)-N-[(5R,6R)-17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-yl]-3-(furan-2-yl)-N-methylprop-2-enamide::CHEMBL485605::TRK-820 Mu-type opioid receptor Cavia cutleri 0.582 ChEMBL 10.1016/j.bmcl.2009.11.027 10.7270/Q2GX4CJH 19962305 Nagase, H; Watanabe, A; Nemoto, T; Yamaotsu, N; Hayashida, K; Nakajima, M; Hasebe, K; Nakao, K; Mochizuki, H; Hirono, S; Fujii, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274257&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44588748 104118082 CHEMBL485605 ZINC45484102 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50914715 CCCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C76H91N17O13/c1-3-4-23-57(69(100)93-64(40-65(95)96)75(106)88-59(66(78)97)35-45-16-7-5-8-17-45)86-73(104)62(38-51-41-83-56-24-14-13-22-54(51)56)91-70(101)58(25-15-32-82-76(79)80)87-71(102)61(37-48-26-29-49-20-11-12-21-50(49)33-48)90-74(105)63(39-52-42-81-43-84-52)92-72(103)60(36-46-18-9-6-10-19-46)89-67(98)44(2)85-68(99)55(77)34-47-27-30-53(94)31-28-47/h5-14,16-22,24,26-31,33,41-44,55,57-64,83,94H,3-4,15,23,25,32,34-40,77H2,1-2H3,(H2,78,97)(H,81,84)(H,85,99)(H,86,104)(H,87,102)(H,88,106)(H,89,98)(H,90,105)(H,91,101)(H,92,103)(H,93,100)(H,95,96)(H4,79,80,82)/t44-,55+,57+,58+,59+,60+,61-,62+,63+,64+/m1/s1 NENKRICCIWXRGU-KGPNUUHGSA-N 50321604 (3S,6S,9S,12S,15R,18S,21S,24R,27S)-18-((1H-imidazol-5-yl)methyl)-9-((1H-indol-3-yl)methyl)-27-amino-3-((S)-1-amino-1-oxo-3-phenylpropan-2-ylcarbamoyl)-21-benzyl-6-butyl-12-(3-guanidinopropyl)-28-(4-hydroxyphenyl)-24-methyl-15-(naphthalen-2-ylmethyl)-5,8,11,14,17,20,23,26-octaoxo-4,7,10,13,16,19,22,25-octaazaoctacosan-1-oic acid::CHEMBL1172429 Mu-type opioid receptor Cavia cutleri 2300 ChEMBL 10.1016/j.bmcl.2010.05.078 10.7270/Q2D79CCN 20547453 Lee, YS; Fernandes, S; Kulkarani, V; Mayorov, A; Davis, P; Ma, SW; Brown, K; Gillies, RJ; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50321604 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50321604&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 91933504 104143133 CHEMBL1172429 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50914717 CCCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C76H90N16O12/c1-4-5-23-58(68(97)90-64(38-66(94)95)73(102)87-60(67(78)96)32-45-16-7-6-8-17-45)85-71(100)62(34-51-39-83-57-24-14-13-22-54(51)57)89-69(98)59(25-15-28-82-76(79)80)86-70(99)61(33-46-26-27-47-18-9-10-19-48(47)31-46)88-72(101)63(36-52-40-81-42-84-52)91-74(103)65-35-49-20-11-12-21-50(49)41-92(65)75(104)56(77)37-55-43(2)29-53(93)30-44(55)3/h6-14,16-22,24,26-27,29-31,39-40,42,56,58-65,83,93H,4-5,15,23,25,28,32-38,41,77H2,1-3H3,(H2,78,96)(H,81,84)(H,85,100)(H,86,99)(H,87,102)(H,88,101)(H,89,98)(H,90,97)(H,91,103)(H,94,95)(H4,79,80,82)/t56-,58-,59-,60-,61+,62-,63-,64-,65+/m0/s1 TVINVHGLLFLSBP-XDVIOIQHSA-N 50321597 (3S,6R,9S,12S,15S,18S)-3-((1H-imidazol-5-yl)methyl)-12-((1H-indol-3-yl)methyl)-18-((S)-1-amino-1-oxo-3-phenylpropan-2-ylcarbamoyl)-1-((R)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinolin-3-yl)-15-butyl-9-(3-guanidinopropyl)-6-(naphthalen-2-ylmethyl)-1,4,7,10,13,16-hexaoxo-2,5,8,11,14,17-hexaazaicosan-20-oic acid::CHEMBL1172249 Mu-type opioid receptor Cavia cutleri 570 ChEMBL 10.1016/j.bmcl.2010.05.078 10.7270/Q2D79CCN 20547453 Lee, YS; Fernandes, S; Kulkarani, V; Mayorov, A; Davis, P; Ma, SW; Brown, K; Gillies, RJ; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50321597 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50321597&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 91933500 104143126 CHEMBL1172249 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50914718 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C74H92ClN19O14/c1-42(87-66(101)52(76)31-45-23-27-50(95)28-24-45)65(100)85-40-62(96)88-58(33-44-15-6-3-7-16-44)68(103)82-29-11-10-19-55(69(104)94-61(37-63(97)98)73(108)91-57(64(78)99)32-43-13-4-2-5-14-43)89-72(107)60(35-47-38-84-54-18-9-8-17-51(47)54)93-70(105)56(20-12-30-83-74(79)80)90-71(106)59(34-46-21-25-48(75)26-22-46)92-67(102)53(77)36-49-39-81-41-86-49/h2-9,13-18,21-28,38-39,41-42,52-53,55-61,84,95H,10-12,19-20,29-37,40,76-77H2,1H3,(H2,78,99)(H,81,86)(H,82,103)(H,85,100)(H,87,101)(H,88,96)(H,89,107)(H,90,106)(H,91,108)(H,92,102)(H,93,105)(H,94,104)(H,97,98)(H4,79,80,83)/t42-,52+,53+,55+,56+,57+,58+,59-,60+,61+/m1/s1 VEMKPSHWNYIGPG-OHNIKRKESA-N 50321601 (2S,5R,11S,18S,21S)-2-amino-21-((S)-1-amino-1-oxo-3-phenylpropan-2-ylcarbamoyl)-18-((S)-2-((S)-2-((R)-2-((S)-2-amino-3-(1H-imidazol-5-yl)propanamido)-3-(4-chlorophenyl)propanamido)-5-guanidinopentanamido)-3-(1H-indol-3-yl)propanamido)-11-benzyl-1-(4-hydroxyphenyl)-5-methyl-3,6,9,12,19-pentaoxo-4,7,10,13,20-pentaazatricosan-23-oic acid::CHEMBL1172245 Mu-type opioid receptor Cavia cutleri 330 ChEMBL 10.1016/j.bmcl.2010.05.078 10.7270/Q2D79CCN 20547453 Lee, YS; Fernandes, S; Kulkarani, V; Mayorov, A; Davis, P; Ma, SW; Brown, K; Gillies, RJ; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50321601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50321601&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 91933503 104143130 CHEMBL1172245 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50914722 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CC(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@H](Cc2ccc3ccccc3c2)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CSSC[C@@H](N)C1=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C68H81N17O13S2/c1-36-21-44(86)22-37(2)46(36)28-47(69)66(97)85-32-57(87)78-54(27-43-31-74-35-77-43)63(94)81-52(25-39-18-19-40-13-6-7-14-41(40)23-39)61(92)79-50(17-10-20-75-68(72)73)60(91)82-53(26-42-30-76-49-16-9-8-15-45(42)49)62(93)84-56(34-100-99-33-48(70)67(85)98)65(96)83-55(29-58(88)89)64(95)80-51(59(71)90)24-38-11-4-3-5-12-38/h3-9,11-16,18-19,21-23,30-31,35,47-48,50-56,76,86H,10,17,20,24-29,32-34,69-70H2,1-2H3,(H2,71,90)(H,74,77)(H,78,87)(H,79,92)(H,80,95)(H,81,94)(H,82,91)(H,83,96)(H,84,93)(H,88,89)(H4,72,73,75)/t47-,48+,50-,51-,52+,53-,54-,55-,56-/m0/s1 YDLLMSIGAKQIBS-KENXXWGUSA-N 50321598 (S)-3-((4R,7S,10S,13R,16S,22S)-16-((1H-imidazol-5-yl)methyl)-7-((1H-indol-3-yl)methyl)-22-amino-20-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-10-(3-guanidinopropyl)-13-(naphthalen-2-ylmethyl)-6,9,12,15,18,21-hexaoxo-1,2-dithia-5,8,11,14,17,20-hexaazacyclotricosane-4-carboxamido)-4-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-4-oxobutanoic acid::CHEMBL1172248 Mu-type opioid receptor Cavia cutleri 280 ChEMBL 10.1016/j.bmcl.2010.05.078 10.7270/Q2D79CCN 20547453 Lee, YS; Fernandes, S; Kulkarani, V; Mayorov, A; Davis, P; Ma, SW; Brown, K; Gillies, RJ; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50321598 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50321598&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 91933501 104143127 CHEMBL1172248 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50914725 CCCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C78H94N18O14/c1-3-4-23-58(71(104)96-65(40-67(99)100)77(110)92-60(68(80)101)35-46-16-7-5-8-17-46)90-75(108)63(38-52-41-85-57-24-14-13-22-55(52)57)94-72(105)59(25-15-32-84-78(81)82)91-74(107)62(37-49-26-29-50-20-11-12-21-51(50)33-49)93-76(109)64(39-53-42-83-44-87-53)95-73(106)61(36-47-18-9-6-10-19-47)89-66(98)43-86-69(102)45(2)88-70(103)56(79)34-48-27-30-54(97)31-28-48/h5-14,16-22,24,26-31,33,41-42,44-45,56,58-65,85,97H,3-4,15,23,25,32,34-40,43,79H2,1-2H3,(H2,80,101)(H,83,87)(H,86,102)(H,88,103)(H,89,98)(H,90,108)(H,91,107)(H,92,110)(H,93,109)(H,94,105)(H,95,106)(H,96,104)(H,99,100)(H4,81,82,84)/t45-,56+,58+,59+,60+,61+,62-,63+,64+,65+/m1/s1 ZZVLKHHSRQKCEV-DVZSIOPJSA-N 50321607 (3S,6S,9S,12S,15R,18S,21S,27R,30S)-18-((1H-imidazol-5-yl)methyl)-9-((1H-indol-3-yl)methyl)-30-amino-3-((S)-1-amino-1-oxo-3-phenylpropan-2-ylcarbamoyl)-21-benzyl-6-butyl-12-(3-guanidinopropyl)-31-(4-hydroxyphenyl)-27-methyl-15-(naphthalen-2-ylmethyl)-5,8,11,14,17,20,23,26,29-nonaoxo-4,7,10,13,16,19,22,25,28-nonaazahentriacontan-1-oic acid::CHEMBL1172252 Mu-type opioid receptor Cavia cutleri 200 ChEMBL 10.1016/j.bmcl.2010.05.078 10.7270/Q2D79CCN 20547453 Lee, YS; Fernandes, S; Kulkarani, V; Mayorov, A; Davis, P; Ma, SW; Brown, K; Gillies, RJ; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50321607 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50321607&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 49798112 104143136 CHEMBL1172252 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50914726 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CC(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@H](Cc2ccccc2)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CSSC[C@@H](N)C1=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C64H79N17O13S2/c1-34-20-40(82)21-35(2)42(34)26-43(65)62(93)81-30-53(83)74-50(25-39-29-70-33-73-39)59(90)77-48(23-37-14-7-4-8-15-37)57(88)75-46(18-11-19-71-64(68)69)56(87)78-49(24-38-28-72-45-17-10-9-16-41(38)45)58(89)80-52(32-96-95-31-44(66)63(81)94)61(92)79-51(27-54(84)85)60(91)76-47(55(67)86)22-36-12-5-3-6-13-36/h3-10,12-17,20-21,28-29,33,43-44,46-52,72,82H,11,18-19,22-27,30-32,65-66H2,1-2H3,(H2,67,86)(H,70,73)(H,74,83)(H,75,88)(H,76,91)(H,77,90)(H,78,87)(H,79,92)(H,80,89)(H,84,85)(H4,68,69,71)/t43-,44+,46-,47-,48+,49-,50-,51-,52-/m0/s1 OYHTUAKSBPLZSH-LTIDWATBSA-N 50321599 (S)-3-((4R,7S,10S,13R,16S,22S)-16-((1H-imidazol-5-yl)methyl)-7-((1H-indol-3-yl)methyl)-22-amino-20-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-13-benzyl-10-(3-guanidinopropyl)-6,9,12,15,18,21-hexaoxo-1,2-dithia-5,8,11,14,17,20-hexaazacyclotricosane-4-carboxamido)-4-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-4-oxobutanoic acid::CHEMBL1172247 Mu-type opioid receptor Cavia cutleri 190 ChEMBL 10.1016/j.bmcl.2010.05.078 10.7270/Q2D79CCN 20547453 Lee, YS; Fernandes, S; Kulkarani, V; Mayorov, A; Davis, P; Ma, SW; Brown, K; Gillies, RJ; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50321599 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50321599&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 91933502 104143128 CHEMBL1172247 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50914729 CCCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C74H92N18O14/c1-3-4-24-54(67(100)92-61(38-63(95)96)73(106)88-56(64(76)97)33-44-17-8-5-9-18-44)86-71(104)59(36-48-39-81-53-25-15-14-23-51(48)53)90-68(101)55(26-16-31-80-74(77)78)87-70(103)58(35-46-21-12-7-13-22-46)89-72(105)60(37-49-40-79-42-83-49)91-69(102)57(34-45-19-10-6-11-20-45)85-62(94)41-82-65(98)43(2)84-66(99)52(75)32-47-27-29-50(93)30-28-47/h5-15,17-23,25,27-30,39-40,42-43,52,54-61,81,93H,3-4,16,24,26,31-38,41,75H2,1-2H3,(H2,76,97)(H,79,83)(H,82,98)(H,84,99)(H,85,94)(H,86,104)(H,87,103)(H,88,106)(H,89,105)(H,90,101)(H,91,102)(H,92,100)(H,95,96)(H4,77,78,80)/t43-,52+,54+,55+,56+,57+,58-,59+,60+,61+/m1/s1 ZUUGDHAKGUQZKD-IDLZVHLMSA-N 50321608 (3S,6S,9S,12S,15R,18S,21S,27R,30S)-18-((1H-imidazol-5-yl)methyl)-9-((1H-indol-3-yl)methyl)-30-amino-3-((S)-1-amino-1-oxo-3-phenylpropan-2-ylcarbamoyl)-15,21-dibenzyl-6-butyl-12-(3-guanidinopropyl)-31-(4-hydroxyphenyl)-27-methyl-5,8,11,14,17,20,23,26,29-nonaoxo-4,7,10,13,16,19,22,25,28-nonaazahentriacontan-1-oic acid::CHEMBL1172251 Mu-type opioid receptor Cavia cutleri 130 ChEMBL 10.1016/j.bmcl.2010.05.078 10.7270/Q2D79CCN 20547453 Lee, YS; Fernandes, S; Kulkarani, V; Mayorov, A; Davis, P; Ma, SW; Brown, K; Gillies, RJ; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50321608 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50321608&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 49798111 104143137 CHEMBL1172251 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50914731 CCCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C78H95N17O13/c1-5-6-25-59(71(102)95-66(40-67(97)98)77(108)90-61(68(80)99)34-47-18-9-7-10-19-47)88-75(106)64(37-52-41-85-58-26-16-15-24-55(52)58)93-72(103)60(27-17-30-84-78(81)82)89-73(104)63(36-49-28-29-50-22-13-14-23-51(50)33-49)92-76(107)65(38-53-42-83-43-86-53)94-74(105)62(35-48-20-11-8-12-21-48)91-69(100)46(4)87-70(101)57(79)39-56-44(2)31-54(96)32-45(56)3/h7-16,18-24,26,28-29,31-33,41-43,46,57,59-66,85,96H,5-6,17,25,27,30,34-40,79H2,1-4H3,(H2,80,99)(H,83,86)(H,87,101)(H,88,106)(H,89,104)(H,90,108)(H,91,100)(H,92,107)(H,93,103)(H,94,105)(H,95,102)(H,97,98)(H4,81,82,84)/t46-,57+,59+,60+,61+,62+,63-,64+,65+,66+/m1/s1 JMDKMESJXNSGPX-PVDMSZGWSA-N 50321605 (6R,9S,12S,15R,18S,21S,24S,27S)-12-((1H-imidazol-5-yl)methyl)-21-((1H-indol-3-yl)methyl)-27-((S)-1-amino-1-oxo-3-phenylpropan-2-ylcarbamoyl)-9-benzyl-24-butyl-18-(3-guanidinopropyl)-1-(4-hydroxy-2,6-dimethylphenyl)-6-methyl-15-(naphthalen-2-ylmethyl)-4,7,10,13,16,19,22,25-octaoxo-3,5,8,11,14,17,20,23,26-nonaazanonacosan-29-oic acid::CHEMBL1172428 Mu-type opioid receptor Cavia cutleri 66 ChEMBL 10.1016/j.bmcl.2010.05.078 10.7270/Q2D79CCN 20547453 Lee, YS; Fernandes, S; Kulkarani, V; Mayorov, A; Davis, P; Ma, SW; Brown, K; Gillies, RJ; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50321605 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50321605&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 91933505 104143134 CHEMBL1172428 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50914734 CCCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C80H98N18O14/c1-5-6-25-60(73(106)98-67(40-69(101)102)79(112)94-62(70(82)103)34-48-18-9-7-10-19-48)92-77(110)65(37-53-41-87-59-26-16-15-24-56(53)59)96-74(107)61(27-17-30-86-80(83)84)93-76(109)64(36-50-28-29-51-22-13-14-23-52(51)33-50)95-78(111)66(38-54-42-85-44-89-54)97-75(108)63(35-49-20-11-8-12-21-49)91-68(100)43-88-71(104)47(4)90-72(105)58(81)39-57-45(2)31-55(99)32-46(57)3/h7-16,18-24,26,28-29,31-33,41-42,44,47,58,60-67,87,99H,5-6,17,25,27,30,34-40,43,81H2,1-4H3,(H2,82,103)(H,85,89)(H,88,104)(H,90,105)(H,91,100)(H,92,110)(H,93,109)(H,94,112)(H,95,111)(H,96,107)(H,97,108)(H,98,106)(H,101,102)(H4,83,84,86)/t47-,58+,60+,61+,62+,63+,64-,65+,66+,67+/m1/s1 AHRZYQWKXXBNHK-UGUSKUCGSA-N 50321606 (3S,6S,9S,12S,15R,18S,21S,27R,30S)-18-((1H-imidazol-5-yl)methyl)-9-((1H-indol-3-yl)methyl)-30-amino-3-((S)-1-amino-1-oxo-3-phenylpropan-2-ylcarbamoyl)-21-benzyl-6-butyl-12-(3-guanidinopropyl)-31-(4-hydroxy-2,6-dimethylphenyl)-27-methyl-15-(naphthalen-2-ylmethyl)-5,8,11,14,17,20,23,26,29-nonaoxo-4,7,10,13,16,19,22,25,28-nonaazahentriacontan-1-oic acid::CHEMBL1172253 Mu-type opioid receptor Cavia cutleri 8.3 ChEMBL 10.1016/j.bmcl.2010.05.078 10.7270/Q2D79CCN 20547453 Lee, YS; Fernandes, S; Kulkarani, V; Mayorov, A; Davis, P; Ma, SW; Brown, K; Gillies, RJ; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50321606 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50321606&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 91933506 104143135 CHEMBL1172253 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50914736 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C23H29N5O5/c1-14(27-23(33)18(24)11-16-7-9-17(29)10-8-16)22(32)26-13-20(30)28-19(21(25)31)12-15-5-3-2-4-6-15/h2-10,14,18-19,29H,11-13,24H2,1H3,(H2,25,31)(H,26,32)(H,27,33)(H,28,30)/t14-,18+,19+/m1/s1 RJEUERNNQHNSKG-CCKFTAQKSA-N 21123 (2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanamide::Enkephalin Amide::YDAGF-NH2 Mu-type opioid receptor Cavia cutleri 47 ChEMBL 10.1016/j.bmcl.2010.05.078 10.7270/Q2D79CCN 20547453 Lee, YS; Fernandes, S; Kulkarani, V; Mayorov, A; Davis, P; Ma, SW; Brown, K; Gillies, RJ; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21123 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21123&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5490373 49689196 ZINC14975452 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50911115 CCC(=O)N(Cc1cccc(CN=C(N)N)c1)C1CCN(CCc2ccccc2)CC1 InChI=1S/C25H35N5O/c1-2-24(31)30(19-22-10-6-9-21(17-22)18-28-25(26)27)23-12-15-29(16-13-23)14-11-20-7-4-3-5-8-20/h3-10,17,23H,2,11-16,18-19H2,1H3,(H4,26,27,28) AQTLLNFIIZDSEL-UHFFFAOYSA-N 50314880 CHEMBL1089542::N-(3-(guanidinomethyl)benzyl)-N-(1-phenethylpiperidin-4-yl)propionamide Mu-type opioid receptor Cavia cutleri 22.4 ChEMBL 10.1021/jm9019068 10.7270/Q21G0N7R 20218625 Weltrowska, G; Chung, NN; Lemieux, C; Guo, J; Lu, Y; Wilkes, BC; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314880 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314880&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46884841 104149241 CHEMBL1089542 ZINC49068204 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50911116 CCC(=O)C(=Cc1cccc(CN=C(N)N)c1)C1CCN(CCc2ccccc2)CC1 InChI=1S/C26H34N4O/c1-2-25(31)24(18-21-9-6-10-22(17-21)19-29-26(27)28)23-12-15-30(16-13-23)14-11-20-7-4-3-5-8-20/h3-10,17-18,23H,2,11-16,19H2,1H3,(H4,27,28,29) LXDISLJEMANODO-UHFFFAOYSA-N 50314881 CHEMBL1089543::CHEMBL1089873::cis-N-(3-(Guanidinomethyl)benzyl)-N-(4-phenylethylcyclohexyl)-propionamide Mu-type opioid receptor Cavia cutleri 521 ChEMBL 10.1021/jm9019068 10.7270/Q21G0N7R 20218625 Weltrowska, G; Chung, NN; Lemieux, C; Guo, J; Lu, Y; Wilkes, BC; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314881 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314881&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46884842 104149242 CHEMBL1089873CHEMBL1089543 ZINC49068206 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50911117 CCC(=O)C(=Cc1cccc(CN=C(N)N)c1)C1CCN(CCc2ccccc2)CC1 InChI=1S/C26H34N4O/c1-2-25(31)24(18-21-9-6-10-22(17-21)19-29-26(27)28)23-12-15-30(16-13-23)14-11-20-7-4-3-5-8-20/h3-10,17-18,23H,2,11-16,19H2,1H3,(H4,27,28,29) LXDISLJEMANODO-UHFFFAOYSA-N 50314881 CHEMBL1089543::CHEMBL1089873::cis-N-(3-(Guanidinomethyl)benzyl)-N-(4-phenylethylcyclohexyl)-propionamide Mu-type opioid receptor Cavia cutleri 590 ChEMBL 10.1021/jm9019068 10.7270/Q21G0N7R 20218625 Weltrowska, G; Chung, NN; Lemieux, C; Guo, J; Lu, Y; Wilkes, BC; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314881 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314881&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46884842 104149242 CHEMBL1089873CHEMBL1089543 ZINC49068206 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50911118 CCC(=O)N(Cc1cccc(C)c1)C1CCN(CCc2ccccc2)CC1 InChI=1S/C24H32N2O/c1-3-24(27)26(19-22-11-7-8-20(2)18-22)23-13-16-25(17-14-23)15-12-21-9-5-4-6-10-21/h4-11,18,23H,3,12-17,19H2,1-2H3 MZSFZQSYRHNECT-UHFFFAOYSA-N 50314883 CHEMBL1089546::N-(3-Methylbenzyl)-N-(1-phenylethylpiperidine-4-yl)propionamide Mu-type opioid receptor Cavia cutleri 647 ChEMBL 10.1021/jm9019068 10.7270/Q21G0N7R 20218625 Weltrowska, G; Chung, NN; Lemieux, C; Guo, J; Lu, Y; Wilkes, BC; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314883 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314883&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 46196788 104149244 CHEMBL1089546 ZINC49112470 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50911119 CCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 InChI=1S/C22H28N2O/c1-2-22(25)24(20-11-7-4-8-12-20)21-14-17-23(18-15-21)16-13-19-9-5-3-6-10-19/h3-12,21H,2,13-18H2,1H3 PJMPHNIQZUBGLI-UHFFFAOYSA-N 50008984 4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-phthalazin-1-one::CHEMBL596::Duragesic-100::Duragesic-12::Duragesic-25::Duragesic-50::Duragesic-75::FENTANYL::FENTANYL CITRATE::FENTANYL-HCl::Fentanyl-100::Fentanyl-12::Fentanyl-25::Fentanyl-50::Fentanyl-75::Fentora::Innovar::Ionsys::N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide::N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide(Fentanyl)::N-(1-phenethylpiperidin-4-yl)-N-phenylpropionamide Mu-type opioid receptor Cavia cutleri 3.45 ChEMBL 10.1021/jm9019068 10.7270/Q21G0N7R 20218625 Weltrowska, G; Chung, NN; Lemieux, C; Guo, J; Lu, Y; Wilkes, BC; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008984&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 7V7 5TZO,8EF5,7U64 3345 103922051 119915 CHEMBL596 DB00813 1626 ZINC02522669 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50919727 CCCC[C@@H](NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC(CC1)N(C(=O)CC)c1ccccc1 InChI=1S/C42H56N6O6/c1-5-7-18-36(46-40(52)35(43)26-34-28(3)23-33(49)24-29(34)4)41(53)44-27-38(50)45-37(25-30-14-10-8-11-15-30)42(54)47-21-19-32(20-22-47)48(39(51)6-2)31-16-12-9-13-17-31/h8-17,23-24,32,35-37,49H,5-7,18-22,25-27,43H2,1-4H3,(H,44,53)(H,45,50)(H,46,52)/t35-,36+,37-/m0/s1 QVBNXGNXRIPRPX-QOEXFKEZSA-N 50334991 (R)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)-N-(2-oxo-2-((S)-1-oxo-3-phenyl-1-(4-(N-phenylpropionamido)piperidin-1-yl)propan-2-ylamino)ethyl)hexanamide::CHEMBL1649938 Mu-type opioid receptor Cavia cutleri 1.6 ChEMBL 10.1021/jm100982d 10.7270/Q2N29XWF 21128594 Cowell, SM; Hanlon, KE University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334991 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334991&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 50994380 125085093 CHEMBL1649938 ZINC72123716 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50919728 CCCC[C@@H](NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC(CC1)N(C(=O)CC)c1ccccc1 InChI=1S/C40H53N5O5/c1-5-7-18-35(42-38(48)34(41)26-33-27(3)23-32(46)24-28(33)4)39(49)43-36(25-29-14-10-8-11-15-29)40(50)44-21-19-31(20-22-44)45(37(47)6-2)30-16-12-9-13-17-30/h8-17,23-24,31,34-36,46H,5-7,18-22,25-26,41H2,1-4H3,(H,42,48)(H,43,49)/t34-,35+,36-/m0/s1 DFQPGELUWSIWCI-PDHQKIGBSA-N 50334992 (R)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)-N-((S)-1-oxo-3-phenyl-1-(4-(N-phenylpropionamido)piperidin-1-yl)propan-2-yl)hexanamide::CHEMBL1649939 Mu-type opioid receptor Cavia cutleri 4.7 ChEMBL 10.1021/jm100982d 10.7270/Q2N29XWF 21128594 Cowell, SM; Hanlon, KE University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334992&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 50994381 125085094 CHEMBL1649939 ZINC72126811 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50919729 CCC(=O)N(C1CCN(CC1)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)c1ccccc1 InChI=1S/C37H47N5O5/c1-5-34(44)42(28-14-10-7-11-15-28)29-16-18-41(19-17-29)37(47)33(22-27-12-8-6-9-13-27)40-35(45)26(4)39-36(46)32(38)23-31-24(2)20-30(43)21-25(31)3/h6-15,20-21,26,29,32-33,43H,5,16-19,22-23,38H2,1-4H3,(H,39,46)(H,40,45)/t26-,32+,33+/m1/s1 XYWSGXJRLJYNDA-DJDPXSJISA-N 50334993 (S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-((R)-1-oxo-1-((S)-1-oxo-3-phenyl-1-(4-(N-phenylpropionamido)piperidin-1-yl)propan-2-ylamino)propan-2-yl)propanamide::CHEMBL1649940 Mu-type opioid receptor Cavia cutleri 3.6 ChEMBL 10.1021/jm100982d 10.7270/Q2N29XWF 21128594 Cowell, SM; Hanlon, KE University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334993&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 50994458 125085095 CHEMBL1649940 ZINC66099628 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50919730 CCCC[C@@H](NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)NCC(=O)N[C@@H](Cc1ccc(Cl)cc1)C(=O)N1CCC(CC1)N(C(=O)CC)c1ccccc1 InChI=1S/C42H55ClN6O6/c1-5-7-13-36(47-40(53)35(44)25-34-27(3)22-33(50)23-28(34)4)41(54)45-26-38(51)46-37(24-29-14-16-30(43)17-15-29)42(55)48-20-18-32(19-21-48)49(39(52)6-2)31-11-9-8-10-12-31/h8-12,14-17,22-23,32,35-37,50H,5-7,13,18-21,24-26,44H2,1-4H3,(H,45,54)(H,46,51)(H,47,53)/t35-,36+,37-/m0/s1 QOTSIQBGDAQKCQ-QOEXFKEZSA-N 50334994 (R)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)-N-(2-((S)-3-(4-chlorophenyl)-1-oxo-1-(4-(N-phenylpropionamido)piperidin-1-yl)propan-2-ylamino)-2-oxoethyl)hexanamide::CHEMBL1649941 Mu-type opioid receptor Cavia cutleri 1.3 ChEMBL 10.1021/jm100982d 10.7270/Q2N29XWF 21128594 Cowell, SM; Hanlon, KE University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334994&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 50994459 125085096 CHEMBL1649941 ZINC95547375 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50919731 CCCC[C@@H](NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)NCC(=O)N[C@@H](Cc1ccc(F)cc1)C(=O)N1CCC(CC1)N(C(=O)CC)c1ccccc1 InChI=1S/C42H55FN6O6/c1-5-7-13-36(47-40(53)35(44)25-34-27(3)22-33(50)23-28(34)4)41(54)45-26-38(51)46-37(24-29-14-16-30(43)17-15-29)42(55)48-20-18-32(19-21-48)49(39(52)6-2)31-11-9-8-10-12-31/h8-12,14-17,22-23,32,35-37,50H,5-7,13,18-21,24-26,44H2,1-4H3,(H,45,54)(H,46,51)(H,47,53)/t35-,36+,37-/m0/s1 KUBFMPDEEMIMDT-QOEXFKEZSA-N 50334995 (R)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)-N-(2-((S)-3-(4-fluorophenyl)-1-oxo-1-(4-(N-phenylpropionamido)piperidin-1-yl)propan-2-ylamino)-2-oxoethyl)hexanamide::CHEMBL1649942 Mu-type opioid receptor Cavia cutleri 0.260000 ChEMBL 10.1021/jm100982d 10.7270/Q2N29XWF 21128594 Cowell, SM; Hanlon, KE University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334995 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334995&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 50994460 125085097 CHEMBL1649942 ZINC95547376 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50919732 CCC(=O)N(C1CCN(CC1)C(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)c1ccccc1 InChI=1S/C39H49ClN6O6/c1-5-36(49)46(29-9-7-6-8-10-29)30-15-17-45(18-16-30)39(52)34(21-27-11-13-28(40)14-12-27)44-35(48)23-42-37(50)26(4)43-38(51)33(41)22-32-24(2)19-31(47)20-25(32)3/h6-14,19-20,26,30,33-34,47H,5,15-18,21-23,41H2,1-4H3,(H,42,50)(H,43,51)(H,44,48)/t26-,33+,34+/m1/s1 KLGSIEGKQXHQIC-VECIQGBVSA-N 50334996 (S)-2-amino-N-((R)-1-(2-((S)-3-(4-chlorophenyl)-1-oxo-1-(4-(N-phenylpropionamido)piperidin-1-yl)propan-2-ylamino)-2-oxoethylamino)-1-oxopropan-2-yl)-3-(4-hydroxy-2,6-dimethylphenyl)propanamide::CHEMBL1649943 Mu-type opioid receptor Cavia cutleri 2.6 ChEMBL 10.1021/jm100982d 10.7270/Q2N29XWF 21128594 Cowell, SM; Hanlon, KE University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334996&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 50925450 125085098 CHEMBL1649943 ZINC72126780 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50919733 CCCC[C@@H](NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](Cc1ccc(Cl)cc1)C(=O)N1CCC(CC1)N(C(=O)CC)c1ccccc1 InChI=1S/C40H52ClN5O5/c1-5-7-13-35(43-38(49)34(42)25-33-26(3)22-32(47)23-27(33)4)39(50)44-36(24-28-14-16-29(41)17-15-28)40(51)45-20-18-31(19-21-45)46(37(48)6-2)30-11-9-8-10-12-30/h8-12,14-17,22-23,31,34-36,47H,5-7,13,18-21,24-25,42H2,1-4H3,(H,43,49)(H,44,50)/t34-,35+,36-/m0/s1 NBCAOCVSBZCMGG-PDHQKIGBSA-N 50334997 (R)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)-N-((S)-3-(4-chlorophenyl)-1-oxo-1-(4-(N-phenylpropionamido)piperidin-1-yl)propan-2-yl)hexanamide::CHEMBL1649944 Mu-type opioid receptor Cavia cutleri 220 ChEMBL 10.1021/jm100982d 10.7270/Q2N29XWF 21128594 Cowell, SM; Hanlon, KE University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334997 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334997&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 50994461 125085099 CHEMBL1649944 ZINC72126771 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50919734 CCC(=O)N(C1CCN(CC1)C(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)c1ccccc1 InChI=1S/C37H46ClN5O5/c1-5-34(45)43(28-9-7-6-8-10-28)29-15-17-42(18-16-29)37(48)33(21-26-11-13-27(38)14-12-26)41-35(46)25(4)40-36(47)32(39)22-31-23(2)19-30(44)20-24(31)3/h6-14,19-20,25,29,32-33,44H,5,15-18,21-22,39H2,1-4H3,(H,40,47)(H,41,46)/t25-,32+,33+/m1/s1 BUGZBENJTIQSLX-NRMCGMLCSA-N 50334987 (S)-2-amino-N-((R)-1-((S)-3-(4-chlorophenyl)-1-oxo-1-(4-(N-phenylpropionamido)piperidin-1-yl)propan-2-ylamino)-1-oxopropan-2-yl)-3-(4-hydroxy-2,6-dimethylphenyl)propanamide::CHEMBL1649945 Mu-type opioid receptor Cavia cutleri 93 ChEMBL 10.1021/jm100982d 10.7270/Q2N29XWF 21128594 Cowell, SM; Hanlon, KE University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334987 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334987&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 50994529 125085089 CHEMBL1649945 ZINC72126772 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50919735 CCC(=O)N(C1CCN(CC1)C(=O)[C@H](Cc1ccc(F)cc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)c1ccccc1 InChI=1S/C39H49FN6O6/c1-5-36(49)46(29-9-7-6-8-10-29)30-15-17-45(18-16-30)39(52)34(21-27-11-13-28(40)14-12-27)44-35(48)23-42-37(50)26(4)43-38(51)33(41)22-32-24(2)19-31(47)20-25(32)3/h6-14,19-20,26,30,33-34,47H,5,15-18,21-23,41H2,1-4H3,(H,42,50)(H,43,51)(H,44,48)/t26-,33+,34+/m1/s1 TYSGVXSEKGDKQO-VECIQGBVSA-N 50334988 (S)-2-amino-N-((R)-1-(2-((S)-3-(4-fluorophenyl)-1-oxo-1-(4-(N-phenylpropionamido)piperidin-1-yl)propan-2-ylamino)-2-oxoethylamino)-1-oxopropan-2-yl)-3-(4-hydroxy-2,6-dimethylphenyl)propanamide::CHEMBL1649946 Mu-type opioid receptor Cavia cutleri 1 ChEMBL 10.1021/jm100982d 10.7270/Q2N29XWF 21128594 Cowell, SM; Hanlon, KE University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334988 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334988&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 50994530 125085090 CHEMBL1649946 ZINC72126773 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50919736 CCC(=O)N(C1CCN(CC1)C(=O)[C@H](Cc1ccc(F)cc1)NC(=O)CNC(=O)[C@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)c1ccccc1 InChI=1S/C46H53FN6O6/c1-4-43(56)53(35-12-6-5-7-13-35)36-18-20-51(21-19-36)46(59)40(24-31-14-16-34(47)17-15-31)50-42(55)27-49-44(57)41-25-32-10-8-9-11-33(32)28-52(41)45(58)39(48)26-38-29(2)22-37(54)23-30(38)3/h5-17,22-23,36,39-41,54H,4,18-21,24-28,48H2,1-3H3,(H,49,57)(H,50,55)/t39-,40-,41+/m0/s1 BLZCMPIPJYNCCB-YZBUDRBASA-N 50334989 (R)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-N-(2-((S)-3-(4-fluorophenyl)-1-oxo-1-(4-(N-phenylpropionamido)piperidin-1-yl)propan-2-ylamino)-2-oxoethyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::CHEMBL1649947 Mu-type opioid receptor Cavia cutleri 0.960000 ChEMBL 10.1021/jm100982d 10.7270/Q2N29XWF 21128594 Cowell, SM; Hanlon, KE University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334989 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334989&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 50994531 125085091 CHEMBL1649947 ZINC95547378 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50919737 CCC(=O)N(C1CCN(CC1)C(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)CNC(=O)[C@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)c1ccccc1 InChI=1S/C46H53ClN6O6/c1-4-43(56)53(35-12-6-5-7-13-35)36-18-20-51(21-19-36)46(59)40(24-31-14-16-34(47)17-15-31)50-42(55)27-49-44(57)41-25-32-10-8-9-11-33(32)28-52(41)45(58)39(48)26-38-29(2)22-37(54)23-30(38)3/h5-17,22-23,36,39-41,54H,4,18-21,24-28,48H2,1-3H3,(H,49,57)(H,50,55)/t39-,40-,41+/m0/s1 VOUSYZRDPWNPDY-YZBUDRBASA-N 50334990 (R)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-N-(2-((S)-3-(4-chlorophenyl)-1-oxo-1-(4-(N-phenylpropionamido)piperidin-1-yl)propan-2-ylamino)-2-oxoethyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide::CHEMBL1649948 Mu-type opioid receptor Cavia cutleri 4.8 ChEMBL 10.1021/jm100982d 10.7270/Q2N29XWF 21128594 Cowell, SM; Hanlon, KE University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334990 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334990&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 50994602 125085092 CHEMBL1649948 ZINC95547379 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50919738 CCC(=O)N(C1CCN(CC1)C(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)c1ccccc1 InChI=1S/C39H50N6O6/c1-5-36(48)45(29-14-10-7-11-15-29)30-16-18-44(19-17-30)39(51)34(22-28-12-8-6-9-13-28)43-35(47)24-41-37(49)27(4)42-38(50)33(40)23-32-25(2)20-31(46)21-26(32)3/h6-15,20-21,27,30,33-34,46H,5,16-19,22-24,40H2,1-4H3,(H,41,49)(H,42,50)(H,43,47)/t27-,33+,34+/m1/s1 XEGINLDCVLRGAF-KUSJRIKGSA-N 21121 (2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-[(1R)-1-[({[(2S)-1-oxo-3-phenyl-1-[4-(N-phenylpropanamido)piperidin-1-yl]propan-2-yl]carbamoyl}methyl)carbamoyl]ethyl]propanamide::4-anilidopiperidine, 16 Mu-type opioid receptor Cavia cutleri 8.5 ChEMBL 10.1021/jm100982d 10.7270/Q2N29XWF 21128594 Cowell, SM; Hanlon, KE University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21121&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 24768397 49689194 ZINC28865012 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50919739 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C23H29N5O5/c1-14(27-23(33)18(24)11-16-7-9-17(29)10-8-16)22(32)26-13-20(30)28-19(21(25)31)12-15-5-3-2-4-6-15/h2-10,14,18-19,29H,11-13,24H2,1H3,(H2,25,31)(H,26,32)(H,27,33)(H,28,30)/t14-,18+,19+/m1/s1 RJEUERNNQHNSKG-CCKFTAQKSA-N 21123 (2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanamide::Enkephalin Amide::YDAGF-NH2 Mu-type opioid receptor Cavia cutleri 47 ChEMBL 10.1021/jm100982d 10.7270/Q2N29XWF 21128594 Cowell, SM; Hanlon, KE University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21123 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21123&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5490373 49689196 ZINC14975452 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50922707 Oc1ccc2CC34CCC(=O)CC3(CCN(CC3CC3)C4)c2c1 InChI=1S/C20H25NO2/c22-16-4-3-15-10-19-6-5-17(23)11-20(19,18(15)9-16)7-8-21(13-19)12-14-1-2-14/h3-4,9,14,22H,1-2,5-8,10-13H2 URRUFILTYRZJKZ-UHFFFAOYSA-N 50347174 CHEMBL1797684 Mu-type opioid receptor Cavia cutleri 58.2 ChEMBL 10.1016/j.bmcl.2011.04.147 10.7270/Q25M66P3 21641798 Yamamoto, N; Fujii, H; Nemoto, T; Nakajima, R; Momen, S; Izumimoto, N; Hasebe, K; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347174 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347174&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 53307791 136353860 CHEMBL1797684 ZINC72170728 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50922708 CN1CCC23CC(=O)CCC2(Cc2ccc(O)cc32)C1 InChI=1S/C17H21NO2/c1-18-7-6-17-10-14(20)4-5-16(17,11-18)9-12-2-3-13(19)8-15(12)17/h2-3,8,19H,4-7,9-11H2,1H3 WUCQEQZEZVRUJS-UHFFFAOYSA-N 50347175 CHEMBL1797685 Mu-type opioid receptor Cavia cutleri 3.6 ChEMBL 10.1016/j.bmcl.2011.04.147 10.7270/Q25M66P3 21641798 Yamamoto, N; Fujii, H; Nemoto, T; Nakajima, R; Momen, S; Izumimoto, N; Hasebe, K; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347175 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347175&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 53307790 136353861 CHEMBL1797685 ZINC72170766 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50922709 Oc1ccc2CC34CCC(=O)CC3(CCN(CC3(O)CC3)C4)c2c1 InChI=1S/C20H25NO3/c22-15-2-1-14-10-18-4-3-16(23)11-20(18,17(14)9-15)7-8-21(12-18)13-19(24)5-6-19/h1-2,9,22,24H,3-8,10-13H2 HIXLAMQESUHGDK-UHFFFAOYSA-N 50347176 CHEMBL1797686 Mu-type opioid receptor Cavia cutleri 77.7 ChEMBL 10.1016/j.bmcl.2011.04.147 10.7270/Q25M66P3 21641798 Yamamoto, N; Fujii, H; Nemoto, T; Nakajima, R; Momen, S; Izumimoto, N; Hasebe, K; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347176&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 53307605 136353862 CHEMBL1797686 ZINC72170958 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50922710 CCC12CCN(CC3(O)CC3)[C@H](Cc3ccc(O)cc13)C2(C)C InChI=1S/C20H29NO2/c1-4-20-9-10-21(13-19(23)7-8-19)17(18(20,2)3)11-14-5-6-15(22)12-16(14)20/h5-6,12,17,22-23H,4,7-11,13H2,1-3H3/t17-,20?/m1/s1 ZDXGFIXMPOUDFF-DIAVIDTQSA-N 50347177 CHEMBL1797687 Mu-type opioid receptor Cavia cutleri 0.2 ChEMBL 10.1016/j.bmcl.2011.04.147 10.7270/Q25M66P3 21641798 Yamamoto, N; Fujii, H; Nemoto, T; Nakajima, R; Momen, S; Izumimoto, N; Hasebe, K; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347177 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347177&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 107697 136353863 CHEMBL1797687 ZINC03870315 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50922711 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 1.1 ChEMBL 10.1016/j.bmcl.2011.04.147 10.7270/Q25M66P3 21641798 Yamamoto, N; Fujii, H; Nemoto, T; Nakajima, R; Momen, S; Izumimoto, N; Hasebe, K; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50922712 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)CCC4=O)ccc5O InChI=1S/C17H19NO4/c1-18-7-6-16-13-9-2-3-10(19)14(13)22-15(16)11(20)4-5-17(16,21)12(18)8-9/h2-3,12,15,19,21H,4-8H2,1H3/t12-,15+,16+,17-/m1/s1 UQCNKQCJZOAFTQ-ISWURRPUSA-N 50001707 10,17-dihydroxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::10,17-dihydroxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(oxymorphone)::10,17-dihydroxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(xymorphone)::10,17-dihydroxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-trien-14-one::CHEMBL963::Codoxy::Combunox::Numorphan::OXYMORPHONE::Opana::Oxycet::PERCODAN-DEMI::Percocet::Percodan::Roxicet::Roxilox::Roxiprin::Tylox::Tylox-325 Mu-type opioid receptor Cavia cutleri 0.54 ChEMBL 10.1016/j.bmcl.2011.04.147 10.7270/Q25M66P3 21641798 Yamamoto, N; Fujii, H; Nemoto, T; Nakajima, R; Momen, S; Izumimoto, N; Hasebe, K; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001707 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001707&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5284604 103916122 CHEMBL963 DB01192 7094 C08019 ZINC03875483 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50922713 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45C(Oc1c24)C1(O)CC[C@@]35OC1 InChI=1S/C21H25NO4/c23-14-4-3-13-9-15-21-6-5-19(24,11-25-21)18-20(21,16(13)17(14)26-18)7-8-22(15)10-12-1-2-12/h3-4,12,15,18,23-24H,1-2,5-11H2/t15-,18?,19?,20+,21-/m1/s1 NOOSMRUESWMKBO-JPRXFOQLSA-N 50347178 CHEMBL1797688 Mu-type opioid receptor Cavia cutleri 0.16 ChEMBL 10.1016/j.bmcl.2011.04.147 10.7270/Q25M66P3 21641798 Yamamoto, N; Fujii, H; Nemoto, T; Nakajima, R; Momen, S; Izumimoto, N; Hasebe, K; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347178 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347178&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 56683415 136353864 CHEMBL1797688 ZINC72171047 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50922714 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]4(CC(=O)CC[C@@]34O)c2c1 InChI=1S/C20H25NO3/c22-15-4-3-14-9-18-20(24)6-5-16(23)11-19(20,17(14)10-15)7-8-21(18)12-13-1-2-13/h3-4,10,13,18,22,24H,1-2,5-9,11-12H2/t18-,19-,20-/m1/s1 JKSUUZMNWGEVRC-VAMGGRTRSA-N 50347179 CHEMBL1797689 Mu-type opioid receptor Cavia cutleri 0.14 ChEMBL 10.1016/j.bmcl.2011.04.147 10.7270/Q25M66P3 21641798 Yamamoto, N; Fujii, H; Nemoto, T; Nakajima, R; Momen, S; Izumimoto, N; Hasebe, K; Mochizuki, H; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347179 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347179&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5493351 136353865 CHEMBL1797689 ZINC38192060 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50942596 N[C@@H](Cc1ccc(O)cc1)C(=O)N1C[C@@H](N)C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C32H38N6O5/c33-23-18-28(38(19-23)32(43)25(34)15-22-11-13-24(39)14-12-22)31(42)37-27(17-21-9-5-2-6-10-21)30(41)36-26(29(35)40)16-20-7-3-1-4-8-20/h1-14,23,25-28,39H,15-19,33-34H2,(H2,35,40)(H,36,41)(H,37,42)/t23-,25-,26-,27-,28-/m0/s1 NRDPNHFRRWANSW-BLVAWXTGSA-N 50386560 CHEMBL2048250 Mu-type opioid receptor Cavia cutleri 894.5 ChEMBL 10.1021/jm201402v 10.7270/Q2571D38 22394120 Mollica, A; Pinnen, F; Stefanucci, A; Feliciani, F; Campestre, C; Mannina, L; Sobolev, AP; Lucente, G; Davis, P; Lai, J; Ma, SW; Porreca, F; Hruby, VJ Universit£ di Chieti-Pescara G. d'Annunzio http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50386560 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50386560&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 57385507 160865643 CHEMBL2048250 ZINC84652201 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50972821 CO[C@@]12CC[C@@]3(C[C@@H]1[C@](C)(O)C(C)(C)C)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45 InChI=1S/C29H41NO4/c1-25(2,3)26(4,32)20-15-27-10-11-29(20,33-5)24-28(27)12-13-30(16-17-6-7-17)21(27)14-18-8-9-19(31)23(34-24)22(18)28/h8-9,17,20-21,24,31-32H,6-7,10-16H2,1-5H3/t20-,21-,24-,26+,27-,28+,29+/m1/s1 RMRJXGBAOAMLHD-CTAPUXPBSA-N 50354578 BUPRENORPHINE::US10752592, Compound buprenorphine::US11534436, Compound buprenorphine::US9315514, Buprenorphine Mu-type opioid receptor Cavia cutleri 21 ChEMBL 10.1021/jm301096s 10.7270/Q2M909TS 23043264 Moynihan, HA; Derrick, I; Broadbear, JH; Greedy, BM; Aceto, MD; Harris, LS; Purington, LC; Thomas, MP; Woods, JH; Traynor, JR; Husbands, SM; Lewis, JW University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354578&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9848990 136361264 C08007 ZINC38321402 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50972831 CO[C@@]12CC[C@@]3(C[C@@H]1[C@](C)(O)C(C)(C)C)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45 InChI=1S/C29H41NO4/c1-25(2,3)26(4,32)20-15-27-10-11-29(20,33-5)24-28(27)12-13-30(16-17-6-7-17)21(27)14-18-8-9-19(31)23(34-24)22(18)28/h8-9,17,20-21,24,31-32H,6-7,10-16H2,1-5H3/t20-,21-,24-,26+,27-,28+,29+/m1/s1 RMRJXGBAOAMLHD-CTAPUXPBSA-N 50354578 BUPRENORPHINE::US10752592, Compound buprenorphine::US11534436, Compound buprenorphine::US9315514, Buprenorphine Mu-type opioid receptor Cavia cutleri 1.3 ChEMBL 10.1021/jm301096s 10.7270/Q2M909TS 23043264 Moynihan, HA; Derrick, I; Broadbear, JH; Greedy, BM; Aceto, MD; Harris, LS; Purington, LC; Thomas, MP; Woods, JH; Traynor, JR; Husbands, SM; Lewis, JW University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354578&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9848990 136361264 C08007 ZINC38321402 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50972832 COC(=O)\C=C\C(=O)N[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45 InChI=1S/C25H30N2O6/c1-32-20(30)7-6-19(29)26-16-8-9-25(31)18-12-15-4-5-17(28)22-21(15)24(25,23(16)33-22)10-11-27(18)13-14-2-3-14/h4-7,14,16,18,23,28,31H,2-3,8-13H2,1H3,(H,26,29)/b7-6+/t16-,18-,23+,24+,25-/m1/s1 PQKHESYTSKMWFP-WZJCLRDWSA-N 50247803 Beta-Funeltrexamine::CHEMBL473136::beta-funaltrexamine::methyl (2E)-3-{[(1S,5R,13R,14R,17S)-4-(cyclopropylmethyl)-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10-trien-14-yl]carbamoyl}prop-2-enoate::methyl 3-[4-cyclopropylmethyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-ylcarbamoyl]-(E)-2-propenoate Mu-type opioid receptor Cavia cutleri 0.4 ChEMBL 10.1021/jm301096s 10.7270/Q2M909TS 23043264 Moynihan, HA; Derrick, I; Broadbear, JH; Greedy, BM; Aceto, MD; Harris, LS; Purington, LC; Thomas, MP; Woods, JH; Traynor, JR; Husbands, SM; Lewis, JW University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50247803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50247803&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311018 104102600 CHEMBL473136 1631 C18127 ZINC03995756 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50972833 CO[C@]12CC[C@@]3(C[C@@H]1CNC(=O)\C=C\c1ccccc1)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45 InChI=1S/C33H38N2O4/c1-38-33-14-13-31(18-24(33)19-34-27(37)12-9-21-5-3-2-4-6-21)26-17-23-10-11-25(36)29-28(23)32(31,30(33)39-29)15-16-35(26)20-22-7-8-22/h2-6,9-12,22,24,26,30,36H,7-8,13-20H2,1H3,(H,34,37)/b12-9+/t24-,26-,30-,31-,32+,33-/m1/s1 VUBGOJHJGFQVIC-VEDZNKNSSA-N 50398946 CHEMBL2179263 Mu-type opioid receptor Cavia cutleri 0.7 ChEMBL 10.1021/jm301096s 10.7270/Q2M909TS 23043264 Moynihan, HA; Derrick, I; Broadbear, JH; Greedy, BM; Aceto, MD; Harris, LS; Purington, LC; Thomas, MP; Woods, JH; Traynor, JR; Husbands, SM; Lewis, JW University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50398946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50398946&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10697437 163347970 CHEMBL2179263 ZINC95573967 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50972834 CO[C@]12CC[C@@]3(C[C@@H]1NC(=O)\C=C\c1ccccc1)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45 InChI=1S/C32H36N2O4/c1-37-32-14-13-30(18-24(32)33-26(36)12-9-20-5-3-2-4-6-20)25-17-22-10-11-23(35)28-27(22)31(30,29(32)38-28)15-16-34(25)19-21-7-8-21/h2-6,9-12,21,24-25,29,35H,7-8,13-19H2,1H3,(H,33,36)/b12-9+/t24-,25+,29+,30+,31-,32+/m0/s1 MKPRSYPYTIHVPA-LLGIIEGRSA-N 50398947 CHEMBL2179262 Mu-type opioid receptor Cavia cutleri 0.9 ChEMBL 10.1021/jm301096s 10.7270/Q2M909TS 23043264 Moynihan, HA; Derrick, I; Broadbear, JH; Greedy, BM; Aceto, MD; Harris, LS; Purington, LC; Thomas, MP; Woods, JH; Traynor, JR; Husbands, SM; Lewis, JW University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50398947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50398947&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10744335 163347971 CHEMBL2179262 ZINC95571609 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50972835 COC(=O)\C=C\C(=O)NC[C@H]1C[C@]23CC[C@]1(OC)[C@@H]1Oc4c5c(C[C@H]2N(CC2CC2)CC[C@@]315)ccc4O InChI=1S/C29H36N2O6/c1-35-23(34)8-7-22(33)30-15-19-14-27-9-10-29(19,36-2)26-28(27)11-12-31(16-17-3-4-17)21(27)13-18-5-6-20(32)25(37-26)24(18)28/h5-8,17,19,21,26,32H,3-4,9-16H2,1-2H3,(H,30,33)/b8-7+/t19-,21-,26-,27-,28+,29-/m1/s1 HGWDEKWYGAVQDF-XMSMROCOSA-N 50398948 CHEMBL2179261 Mu-type opioid receptor Cavia cutleri 0.9 ChEMBL 10.1021/jm301096s 10.7270/Q2M909TS 23043264 Moynihan, HA; Derrick, I; Broadbear, JH; Greedy, BM; Aceto, MD; Harris, LS; Purington, LC; Thomas, MP; Woods, JH; Traynor, JR; Husbands, SM; Lewis, JW University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50398948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50398948&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71453746 163347972 CHEMBL2179261 ZINC95575248 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50972836 COC(=O)\C=C\C(=O)N[C@H]1C[C@]23CC[C@]1(OC)[C@@H]1Oc4c5c(C[C@H]2N(CC2CC2)CC[C@@]315)ccc4O InChI=1S/C28H34N2O6/c1-34-22(33)8-7-21(32)29-19-14-26-9-10-28(19,35-2)25-27(26)11-12-30(15-16-3-4-16)20(26)13-17-5-6-18(31)24(36-25)23(17)27/h5-8,16,19-20,25,31H,3-4,9-15H2,1-2H3,(H,29,32)/b8-7+/t19-,20+,25+,26+,27-,28+/m0/s1 WTWXYJSBRDPEQS-GDAFCXFGSA-N 50398949 CHEMBL2179260 Mu-type opioid receptor Cavia cutleri 2.8 ChEMBL 10.1021/jm301096s 10.7270/Q2M909TS 23043264 Moynihan, HA; Derrick, I; Broadbear, JH; Greedy, BM; Aceto, MD; Harris, LS; Purington, LC; Thomas, MP; Woods, JH; Traynor, JR; Husbands, SM; Lewis, JW University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50398949 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50398949&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71462626 163347973 CHEMBL2179260 ZINC95575031 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50972837 COC(=O)CCC(=O)N[C@]12CCC(=O)[C@@H]3Oc4c5c(C[C@H]1N(CC1CC1)CC[C@@]235)ccc4O InChI=1S/C25H30N2O6/c1-32-20(31)7-6-19(30)26-25-9-8-17(29)23-24(25)10-11-27(13-14-2-3-14)18(25)12-15-4-5-16(28)22(33-23)21(15)24/h4-5,14,18,23,28H,2-3,6-13H2,1H3,(H,26,30)/t18-,23+,24+,25-/m1/s1 VJJQYZRXRRIJIU-XELASAAXSA-N 50398950 CHEMBL2179259 Mu-type opioid receptor Cavia cutleri 0.7 ChEMBL 10.1021/jm301096s 10.7270/Q2M909TS 23043264 Moynihan, HA; Derrick, I; Broadbear, JH; Greedy, BM; Aceto, MD; Harris, LS; Purington, LC; Thomas, MP; Woods, JH; Traynor, JR; Husbands, SM; Lewis, JW University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50398950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50398950&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71453745 163347974 CHEMBL2179259 ZINC95579297 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50972838 COC(=O)\C=C\C(=O)O[C@]12CCC(=O)[C@@H]3Oc4c5c(C[C@H]1N(CC1CC1)CC[C@@]235)ccc4O InChI=1S/C25H27NO7/c1-31-19(29)6-7-20(30)33-25-9-8-17(28)23-24(25)10-11-26(13-14-2-3-14)18(25)12-15-4-5-16(27)22(32-23)21(15)24/h4-7,14,18,23,27H,2-3,8-13H2,1H3/b7-6+/t18-,23+,24+,25-/m1/s1 JILUINOXHPIHFM-RDYFDFNXSA-N 50398951 CHEMBL2179258 Mu-type opioid receptor Cavia cutleri 0.2 ChEMBL 10.1021/jm301096s 10.7270/Q2M909TS 23043264 Moynihan, HA; Derrick, I; Broadbear, JH; Greedy, BM; Aceto, MD; Harris, LS; Purington, LC; Thomas, MP; Woods, JH; Traynor, JR; Husbands, SM; Lewis, JW University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50398951 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50398951&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71453744 163347975 CHEMBL2179258 ZINC95575887 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50972839 COC(=O)\C=C\C(=O)N[C@]12CCC(=O)[C@@H]3Oc4c5c(C[C@H]1N(CC1CC1)CC[C@@]235)ccc4O InChI=1S/C25H28N2O6/c1-32-20(31)7-6-19(30)26-25-9-8-17(29)23-24(25)10-11-27(13-14-2-3-14)18(25)12-15-4-5-16(28)22(33-23)21(15)24/h4-7,14,18,23,28H,2-3,8-13H2,1H3,(H,26,30)/b7-6+/t18-,23+,24+,25-/m1/s1 QZDANAWJLUZBMD-RDYFDFNXSA-N 50398952 CHEMBL2179264 Mu-type opioid receptor Cavia cutleri 0.24 ChEMBL 10.1021/jm301096s 10.7270/Q2M909TS 23043264 Moynihan, HA; Derrick, I; Broadbear, JH; Greedy, BM; Aceto, MD; Harris, LS; Purington, LC; Thomas, MP; Woods, JH; Traynor, JR; Husbands, SM; Lewis, JW University of Bristol http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50398952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50398952&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71455484 163347976 CHEMBL2179264 ZINC95574550 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50968424 N[C@@H](Cc1ccc(O)cc1)C(=O)N1C[C@@H](N)C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(N)=O InChI=1S/C32H38N6O5/c33-23-18-28(38(19-23)32(43)25(34)15-22-11-13-24(39)14-12-22)31(42)37-27(17-21-9-5-2-6-10-21)30(41)36-26(29(35)40)16-20-7-3-1-4-8-20/h1-14,23,25-28,39H,15-19,33-34H2,(H2,35,40)(H,36,41)(H,37,42)/t23-,25-,26+,27-,28-/m0/s1 NRDPNHFRRWANSW-ZZMHRXRUSA-N 50397111 CHEMBL2171853 Mu-type opioid receptor Cavia cutleri 2300 ChEMBL 10.1021/jm300947s 10.7270/Q2NP25JD 22966938 Mollica, A; Pinnen, F; Stefanucci, A; Mannina, L; Sobolev, AP; Lucente, G; Davis, P; Lai, J; Ma, SW; Porreca, F; Hruby, VJ Universit£ di Chieti-Pescara G. d'Annunzio http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397111 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397111&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71455270 163346135 CHEMBL2171853 ZINC95555832 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50968425 N[C@@H](Cc1ccc(O)cc1)C(=O)N1C[C@@H]2C[C@H]1C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N2 InChI=1S/C32H35N5O5/c33-25(15-22-11-13-24(38)14-12-22)32(42)37-19-23-18-28(37)31(41)36-27(17-21-9-5-2-6-10-21)30(40)35-26(29(39)34-23)16-20-7-3-1-4-8-20/h1-14,23,25-28,38H,15-19,33H2,(H,34,39)(H,35,40)(H,36,41)/t23?,25-,26-,27+,28-/m0/s1 GCAAWBGPPHFVPO-XMXKMWOXSA-N 50397109 CHEMBL2171847 Mu-type opioid receptor Cavia cutleri 330 ChEMBL 10.1021/jm300947s 10.7270/Q2NP25JD 22966938 Mollica, A; Pinnen, F; Stefanucci, A; Mannina, L; Sobolev, AP; Lucente, G; Davis, P; Lai, J; Ma, SW; Porreca, F; Hruby, VJ Universit£ di Chieti-Pescara G. d'Annunzio http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397109 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397109&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 91928491 163346133 CHEMBL2171847 ZINC95554169 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50968426 N[C@@H](Cc1ccc(O)cc1)C(=O)N1C[C@@H]2C[C@H]1C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(=O)N2 InChI=1S/C32H35N5O5/c33-25(15-22-11-13-24(38)14-12-22)32(42)37-19-23-18-28(37)31(41)36-27(17-21-9-5-2-6-10-21)30(40)35-26(29(39)34-23)16-20-7-3-1-4-8-20/h1-14,23,25-28,38H,15-19,33H2,(H,34,39)(H,35,40)(H,36,41)/t23?,25-,26+,27+,28-/m0/s1 GCAAWBGPPHFVPO-DMFUDNNJSA-N 50397110 CHEMBL2171846 Mu-type opioid receptor Cavia cutleri 480 ChEMBL 10.1021/jm300947s 10.7270/Q2NP25JD 22966938 Mollica, A; Pinnen, F; Stefanucci, A; Mannina, L; Sobolev, AP; Lucente, G; Davis, P; Lai, J; Ma, SW; Porreca, F; Hruby, VJ Universit£ di Chieti-Pescara G. d'Annunzio http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50397110 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50397110&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 91928492 163346134 CHEMBL2171846 ZINC95557613 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50963213 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=C)C(N)=O)c1ccc2ccccc2c1 InChI=1S/C39H40N6O5/c1-23(36(41)47)35(27-15-14-25-7-2-3-8-26(25)20-27)44-37(48)33(21-28-22-42-32-10-5-4-9-30(28)32)43-38(49)34-11-6-18-45(34)39(50)31(40)19-24-12-16-29(46)17-13-24/h2-5,7-10,12-17,20,22,31,33-35,42,46H,1,6,11,18-19,21,40H2,(H2,41,47)(H,43,49)(H,44,48)/t31-,33-,34-,35+/m0/s1 FNQKCFAVVVIHTR-HPSGNIKNSA-N 50395057 CHEMBL2163919 Mu-type opioid receptor Cavia cutleri 18 ChEMBL 10.1021/jm300664y 10.7270/Q2T154S8 22724433 Wang, Y; Xing, Y; Liu, X; Ji, H; Kai, M; Chen, Z; Yu, J; Zhao, D; Ren, H; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395057 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395057&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 60170777 163344081 CHEMBL2163919 ZINC95554710 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50963214 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=C)C(N)=O)c1cccc2ccccc12 InChI=1S/C39H40N6O5/c1-23(36(41)47)35(30-12-6-9-25-8-2-3-10-28(25)30)44-37(48)33(21-26-22-42-32-13-5-4-11-29(26)32)43-38(49)34-14-7-19-45(34)39(50)31(40)20-24-15-17-27(46)18-16-24/h2-6,8-13,15-18,22,31,33-35,42,46H,1,7,14,19-21,40H2,(H2,41,47)(H,43,49)(H,44,48)/t31-,33-,34-,35+/m0/s1 SLZHOAGZSUACQP-HPSGNIKNSA-N 50395058 CHEMBL2163918 Mu-type opioid receptor Cavia cutleri 34 ChEMBL 10.1021/jm300664y 10.7270/Q2T154S8 22724433 Wang, Y; Xing, Y; Liu, X; Ji, H; Kai, M; Chen, Z; Yu, J; Zhao, D; Ren, H; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395058 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395058&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 60170776 163344082 CHEMBL2163918 ZINC95550230 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50963215 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=C)C(N)=O)c1ccoc1 InChI=1S/C33H36N6O6/c1-19(30(35)41)29(21-12-14-45-18-21)38-31(42)27(16-22-17-36-26-6-3-2-5-24(22)26)37-32(43)28-7-4-13-39(28)33(44)25(34)15-20-8-10-23(40)11-9-20/h2-3,5-6,8-12,14,17-18,25,27-29,36,40H,1,4,7,13,15-16,34H2,(H2,35,41)(H,37,43)(H,38,42)/t25-,27-,28-,29+/m0/s1 AIMNNAYOYMPJBT-RDPOUHODSA-N 50395059 CHEMBL2163917 Mu-type opioid receptor Cavia cutleri 3.9 ChEMBL 10.1021/jm300664y 10.7270/Q2T154S8 22724433 Wang, Y; Xing, Y; Liu, X; Ji, H; Kai, M; Chen, Z; Yu, J; Zhao, D; Ren, H; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395059 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395059&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 60170775 163344083 CHEMBL2163917 ZINC95555351 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50963216 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=C)C(N)=O)c1ccco1 InChI=1S/C33H36N6O6/c1-19(30(35)41)29(28-9-5-15-45-28)38-31(42)26(17-21-18-36-25-7-3-2-6-23(21)25)37-32(43)27-8-4-14-39(27)33(44)24(34)16-20-10-12-22(40)13-11-20/h2-3,5-7,9-13,15,18,24,26-27,29,36,40H,1,4,8,14,16-17,34H2,(H2,35,41)(H,37,43)(H,38,42)/t24-,26-,27-,29+/m0/s1 PSYCNOCTJXDXOM-KEQINOFFSA-N 50395060 CHEMBL2163916 Mu-type opioid receptor Cavia cutleri 2.9 ChEMBL 10.1021/jm300664y 10.7270/Q2T154S8 22724433 Wang, Y; Xing, Y; Liu, X; Ji, H; Kai, M; Chen, Z; Yu, J; Zhao, D; Ren, H; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395060 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395060&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 60168107 163344084 CHEMBL2163916 ZINC95554051 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50963217 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=C)C(N)=O)c1ccc2OCOc2c1 InChI=1S/C36H38N6O7/c1-20(33(38)44)32(22-10-13-30-31(17-22)49-19-48-30)41-34(45)28(16-23-18-39-27-6-3-2-5-25(23)27)40-35(46)29-7-4-14-42(29)36(47)26(37)15-21-8-11-24(43)12-9-21/h2-3,5-6,8-13,17-18,26,28-29,32,39,43H,1,4,7,14-16,19,37H2,(H2,38,44)(H,40,46)(H,41,45)/t26-,28-,29-,32+/m0/s1 LFOULBUVHVTXRQ-FHGVHELMSA-N 50395061 CHEMBL2163915 Mu-type opioid receptor Cavia cutleri 14 ChEMBL 10.1021/jm300664y 10.7270/Q2T154S8 22724433 Wang, Y; Xing, Y; Liu, X; Ji, H; Kai, M; Chen, Z; Yu, J; Zhao, D; Ren, H; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395061 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395061&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 60170774 163344085 CHEMBL2163915 ZINC95554104 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50963218 COc1ccc(cc1)[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=C)C(N)=O InChI=1S/C36H40N6O6/c1-21(33(38)44)32(23-11-15-26(48-2)16-12-23)41-34(45)30(19-24-20-39-29-7-4-3-6-27(24)29)40-35(46)31-8-5-17-42(31)36(47)28(37)18-22-9-13-25(43)14-10-22/h3-4,6-7,9-16,20,28,30-32,39,43H,1,5,8,17-19,37H2,2H3,(H2,38,44)(H,40,46)(H,41,45)/t28-,30-,31-,32+/m0/s1 WPWLYNPGSJQWTG-BNAYGLTLSA-N 50395062 CHEMBL2163914 Mu-type opioid receptor Cavia cutleri 84 ChEMBL 10.1021/jm300664y 10.7270/Q2T154S8 22724433 Wang, Y; Xing, Y; Liu, X; Ji, H; Kai, M; Chen, Z; Yu, J; Zhao, D; Ren, H; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395062 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395062&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 60170691 163344086 CHEMBL2163914 ZINC95557147 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50963219 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=C)C(N)=O)c1ccccc1Cl InChI=1S/C35H37ClN6O5/c1-20(32(38)44)31(25-8-2-4-9-26(25)36)41-33(45)29(18-22-19-39-28-10-5-3-7-24(22)28)40-34(46)30-11-6-16-42(30)35(47)27(37)17-21-12-14-23(43)15-13-21/h2-5,7-10,12-15,19,27,29-31,39,43H,1,6,11,16-18,37H2,(H2,38,44)(H,40,46)(H,41,45)/t27-,29-,30-,31+/m0/s1 DHCJRZRLORZUHS-MUFAAYGBSA-N 50395063 CHEMBL2163913 Mu-type opioid receptor Cavia cutleri 17 ChEMBL 10.1021/jm300664y 10.7270/Q2T154S8 22724433 Wang, Y; Xing, Y; Liu, X; Ji, H; Kai, M; Chen, Z; Yu, J; Zhao, D; Ren, H; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395063 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395063&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71453373 163344087 CHEMBL2163913 ZINC95554428 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50963220 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=C)C(N)=O)c1cccc(Cl)c1 InChI=1S/C35H37ClN6O5/c1-20(32(38)44)31(22-6-4-7-24(36)17-22)41-33(45)29(18-23-19-39-28-9-3-2-8-26(23)28)40-34(46)30-10-5-15-42(30)35(47)27(37)16-21-11-13-25(43)14-12-21/h2-4,6-9,11-14,17,19,27,29-31,39,43H,1,5,10,15-16,18,37H2,(H2,38,44)(H,40,46)(H,41,45)/t27-,29-,30-,31+/m0/s1 VLUBSZRNSOYUGD-MUFAAYGBSA-N 50395064 CHEMBL2163912 Mu-type opioid receptor Cavia cutleri 7.7 ChEMBL 10.1021/jm300664y 10.7270/Q2T154S8 22724433 Wang, Y; Xing, Y; Liu, X; Ji, H; Kai, M; Chen, Z; Yu, J; Zhao, D; Ren, H; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395064&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 60170689 163344088 CHEMBL2163912 ZINC95553662 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50963221 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=C)C(N)=O)c1ccc(Cl)cc1 InChI=1S/C35H37ClN6O5/c1-20(32(38)44)31(22-10-12-24(36)13-11-22)41-33(45)29(18-23-19-39-28-6-3-2-5-26(23)28)40-34(46)30-7-4-16-42(30)35(47)27(37)17-21-8-14-25(43)15-9-21/h2-3,5-6,8-15,19,27,29-31,39,43H,1,4,7,16-18,37H2,(H2,38,44)(H,40,46)(H,41,45)/t27-,29-,30-,31+/m0/s1 RGYGFWCKRIHANQ-MUFAAYGBSA-N 50395065 CHEMBL2163911 Mu-type opioid receptor Cavia cutleri 15 ChEMBL 10.1021/jm300664y 10.7270/Q2T154S8 22724433 Wang, Y; Xing, Y; Liu, X; Ji, H; Kai, M; Chen, Z; Yu, J; Zhao, D; Ren, H; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395065&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 60170688 163344089 CHEMBL2163911 ZINC95552058 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50963222 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=C)C(N)=O)c1ccc(F)cc1 InChI=1S/C35H37FN6O5/c1-20(32(38)44)31(22-10-12-24(36)13-11-22)41-33(45)29(18-23-19-39-28-6-3-2-5-26(23)28)40-34(46)30-7-4-16-42(30)35(47)27(37)17-21-8-14-25(43)15-9-21/h2-3,5-6,8-15,19,27,29-31,39,43H,1,4,7,16-18,37H2,(H2,38,44)(H,40,46)(H,41,45)/t27-,29-,30-,31+/m0/s1 OPLCYWPYFIJWRN-MUFAAYGBSA-N 50395066 CHEMBL2163910 Mu-type opioid receptor Cavia cutleri 32 ChEMBL 10.1021/jm300664y 10.7270/Q2T154S8 22724433 Wang, Y; Xing, Y; Liu, X; Ji, H; Kai, M; Chen, Z; Yu, J; Zhao, D; Ren, H; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395066&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 60170611 163344090 CHEMBL2163910 ZINC95556447 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50963223 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=C)C(=O)N[C@H](C(=C)C(N)=O)c1ccccc1)c1ccccc1 InChI=1S/C34H37N5O5/c1-21(31(36)41)29(24-10-5-3-6-11-24)37-32(42)22(2)30(25-12-7-4-8-13-25)38-33(43)28-14-9-19-39(28)34(44)27(35)20-23-15-17-26(40)18-16-23/h3-8,10-13,15-18,27-30,40H,1-2,9,14,19-20,35H2,(H2,36,41)(H,37,42)(H,38,43)/t27-,28-,29+,30+/m0/s1 ZKOITTBBWXMGMR-VZNYXHRGSA-N 50395067 CHEMBL2163922 Mu-type opioid receptor Cavia cutleri 38 ChEMBL 10.1021/jm300664y 10.7270/Q2T154S8 22724433 Wang, Y; Xing, Y; Liu, X; Ji, H; Kai, M; Chen, Z; Yu, J; Zhao, D; Ren, H; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395067&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 60170610 163344091 CHEMBL2163922 ZINC95555433 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50963224 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=C)C(N)=O)c1ccccc1 InChI=1S/C35H38N6O5/c1-21(32(37)43)31(23-8-3-2-4-9-23)40-33(44)29(19-24-20-38-28-11-6-5-10-26(24)28)39-34(45)30-12-7-17-41(30)35(46)27(36)18-22-13-15-25(42)16-14-22/h2-6,8-11,13-16,20,27,29-31,38,42H,1,7,12,17-19,36H2,(H2,37,43)(H,39,45)(H,40,44)/t27-,29-,30-,31+/m0/s1 GOKRYXUMRXWEKJ-MUFAAYGBSA-N 50395068 CHEMBL2163921 Mu-type opioid receptor Cavia cutleri 6.8 ChEMBL 10.1021/jm300664y 10.7270/Q2T154S8 22724433 Wang, Y; Xing, Y; Liu, X; Ji, H; Kai, M; Chen, Z; Yu, J; Zhao, D; Ren, H; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395068 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395068&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 60170609 163344092 CHEMBL2163921 ZINC95553611 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50963225 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O)c1ccccc1 InChI=1S/C33H37N5O5/c1-21(31(41)36-27(30(35)40)20-22-9-4-2-5-10-22)29(24-11-6-3-7-12-24)37-32(42)28-13-8-18-38(28)33(43)26(34)19-23-14-16-25(39)17-15-23/h2-7,9-12,14-17,26-29,39H,1,8,13,18-20,34H2,(H2,35,40)(H,36,41)(H,37,42)/t26-,27-,28-,29+/m0/s1 ROQAGVQWRNDSGI-XFTNXAEASA-N 50395069 CHEMBL2163920 Mu-type opioid receptor Cavia cutleri 21 ChEMBL 10.1021/jm300664y 10.7270/Q2T154S8 22724433 Wang, Y; Xing, Y; Liu, X; Ji, H; Kai, M; Chen, Z; Yu, J; Zhao, D; Ren, H; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395069 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395069&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 60170608 163344093 CHEMBL2163920 ZINC95552827 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50963226 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C32H37N5O5/c33-25(18-23-13-15-24(38)16-14-23)32(42)37-17-7-12-28(37)31(41)36-27(20-22-10-5-2-6-11-22)30(40)35-26(29(34)39)19-21-8-3-1-4-9-21/h1-6,8-11,13-16,25-28,38H,7,12,17-20,33H2,(H2,34,39)(H,35,40)(H,36,41)/t25-,26-,27-,28-/m0/s1 XIJHWXXXIMEHKW-LJWNLINESA-N 50139013 (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::(S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxamide::1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylicacid[1-((S)-(S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL333357::H-Tyr-Pro-Phe-Phe-NH2::Tyr-Pro-Phe-Phe-NH2::endomorphin-2 Mu-type opioid receptor Cavia cutleri 9.3 ChEMBL 10.1021/jm300664y 10.7270/Q2T154S8 22724433 Wang, Y; Xing, Y; Liu, X; Ji, H; Kai, M; Chen, Z; Yu, J; Zhao, D; Ren, H; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139013&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311081 104029000 CHEMBL333357 3668 ZINC14951634 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50963227 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C34H38N6O5/c35-26(17-22-12-14-24(41)15-13-22)34(45)40-16-6-11-30(40)33(44)39-29(19-23-20-37-27-10-5-4-9-25(23)27)32(43)38-28(31(36)42)18-21-7-2-1-3-8-21/h1-5,7-10,12-15,20,26,28-30,37,41H,6,11,16-19,35H2,(H2,36,42)(H,38,43)(H,39,44)/t26-,28-,29-,30-/m0/s1 ZEXLJFNSKAHNFH-SYKYGTKKSA-N 50095155 (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide::(S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxamide::1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [1-((S)-(S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide::1-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [1-(1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide::CHEMBL316446::ENDOMORPHIN-1::H-Tyr-Pro-Trp-Phe-NH2::Tyr-Pro-Trp-Phe-NH2::YPWF-NH2::endomorphin -1 Mu-type opioid receptor Cavia cutleri 14 ChEMBL 10.1021/jm300664y 10.7270/Q2T154S8 22724433 Wang, Y; Xing, Y; Liu, X; Ji, H; Kai, M; Chen, Z; Yu, J; Zhao, D; Ren, H; Wang, R Lanzhou University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095155&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311080 103992914 CHEMBL316446 1623 ZINC14951658 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50981026 Oc1ccc2CC34CC5C(=O)CC3N(CC3CC3)CCC4(CC5=O)c2c1 InChI=1S/C22H25NO3/c24-15-4-3-14-9-22-10-16-18(25)8-20(22)23(12-13-1-2-13)6-5-21(22,11-19(16)26)17(14)7-15/h3-4,7,13,16,20,24H,1-2,5-6,8-12H2 WWZJATZYCGKHLQ-UHFFFAOYSA-N 50402137 CHEMBL2207677 Mu-type opioid receptor Cavia cutleri 187 ChEMBL 10.1016/j.bmcl.2012.09.102 10.7270/Q2DN466K 23116891 Fujii, H; Nakajima, R; Akiyama, J; Yamamoto, N; Hirayama, S; Nemoto, T; Gouda, H; Hirono, S; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402137 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402137&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71452533 163351161 CHEMBL2207677 ZINC95560148 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50981027 Oc1ccc2CC34CC5CCC3N(CC3CC3)CCC4(CC5=O)c2c1 InChI=1S/C22H27NO2/c24-17-5-3-15-10-22-11-16-4-6-20(22)23(13-14-1-2-14)8-7-21(22,12-19(16)25)18(15)9-17/h3,5,9,14,16,20,24H,1-2,4,6-8,10-13H2 BQPOPACASUDVEO-UHFFFAOYSA-N 50402138 CHEMBL2207678 Mu-type opioid receptor Cavia cutleri 3.21 ChEMBL 10.1016/j.bmcl.2012.09.102 10.7270/Q2DN466K 23116891 Fujii, H; Nakajima, R; Akiyama, J; Yamamoto, N; Hirayama, S; Nemoto, T; Gouda, H; Hirono, S; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402138 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402138&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71452534 163351162 CHEMBL2207678 ZINC95564200 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50981028 Oc1ccc2CC34CC5C=CC3N(CC3CC3)CCC4(CC5=O)c2c1 InChI=1S/C22H25NO2/c24-17-5-3-15-10-22-11-16-4-6-20(22)23(13-14-1-2-14)8-7-21(22,12-19(16)25)18(15)9-17/h3-6,9,14,16,20,24H,1-2,7-8,10-13H2 YBGZJSFLDRPPQS-UHFFFAOYSA-N 50402139 CHEMBL2207679 Mu-type opioid receptor Cavia cutleri 17.6 ChEMBL 10.1016/j.bmcl.2012.09.102 10.7270/Q2DN466K 23116891 Fujii, H; Nakajima, R; Akiyama, J; Yamamoto, N; Hirayama, S; Nemoto, T; Gouda, H; Hirono, S; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402139 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402139&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71461483 163351163 CHEMBL2207679 ZINC95562472 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50981029 O[C@@H]1CC2N(CC3CC3)CCC34CC(=O)C1CC23Cc1ccc(O)cc41 InChI=1S/C22H27NO3/c24-15-4-3-14-9-22-10-16-18(25)8-20(22)23(12-13-1-2-13)6-5-21(22,11-19(16)26)17(14)7-15/h3-4,7,13,16,18,20,24-25H,1-2,5-6,8-12H2/t16?,18-,20?,21?,22?/m1/s1 LOXFETCCXNYJIL-UKNOQSLZSA-N 50402140 CHEMBL2207680 Mu-type opioid receptor Cavia cutleri 13.1 ChEMBL 10.1016/j.bmcl.2012.09.102 10.7270/Q2DN466K 23116891 Fujii, H; Nakajima, R; Akiyama, J; Yamamoto, N; Hirayama, S; Nemoto, T; Gouda, H; Hirono, S; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402140 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402140&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71456047 163351164 CHEMBL2207680 ZINC95562542 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50981030 O[C@H]1CC2N(CC3CC3)CCC34CC(=O)C1CC23Cc1ccc(O)cc41 InChI=1S/C22H27NO3/c24-15-4-3-14-9-22-10-16-18(25)8-20(22)23(12-13-1-2-13)6-5-21(22,11-19(16)26)17(14)7-15/h3-4,7,13,16,18,20,24-25H,1-2,5-6,8-12H2/t16?,18-,20?,21?,22?/m0/s1 LOXFETCCXNYJIL-JSCXXUSDSA-N 50402141 CHEMBL2207681 Mu-type opioid receptor Cavia cutleri 70.7 ChEMBL 10.1016/j.bmcl.2012.09.102 10.7270/Q2DN466K 23116891 Fujii, H; Nakajima, R; Akiyama, J; Yamamoto, N; Hirayama, S; Nemoto, T; Gouda, H; Hirono, S; Nagase, H Kitasato University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50402141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50402141&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71461484 163351165 CHEMBL2207681 ZINC95563380 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50974519 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=O)C(=O)N[C@H]1Cc2ccccc2CN([C@@H](CCCCN)C(N)=O)C1=O InChI=1S/C33H48N8O6/c1-19-14-23(42)15-20(2)24(19)17-25(35)30(44)39-26(10-7-13-38-33(37)47)31(45)40-27-16-21-8-3-4-9-22(21)18-41(32(27)46)28(29(36)43)11-5-6-12-34/h3-4,8-9,14-15,25-28,42H,5-7,10-13,16-18,34-35H2,1-2H3,(H2,36,43)(H,39,44)(H,40,45)(H3,37,38,47)/t25-,26+,27-,28-/m0/s1 ULEAONYLHPWGFF-PUHABZHSSA-N 50399635 CHEMBL2181192 Mu-type opioid receptor Cavia cutleri 49 ChEMBL 10.1021/jm3008079 10.7270/Q2TM7C82 23102273 Novoa, A; Van Dorpe, S; Wynendaele, E; Spetea, M; Bracke, N; Stalmans, S; Betti, C; Chung, NN; Lemieux, C; Zuegg, J; Cooper, MA; Tourwe, D; De Spiegeleer, B; Schiller, PW; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50399635 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50399635&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71462782 163348659 CHEMBL2181192 ZINC95574044 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50974520 CCCC[C@H](N1Cc2ccccc2C[C@H](NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C1=O)C(N)=O InChI=1S/C33H48N8O5/c1-4-5-12-28(29(35)43)41-18-22-10-7-6-9-21(22)16-27(32(41)46)40-31(45)26(11-8-13-38-33(36)37)39-30(44)25(34)17-24-19(2)14-23(42)15-20(24)3/h6-7,9-10,14-15,25-28,42H,4-5,8,11-13,16-18,34H2,1-3H3,(H2,35,43)(H,39,44)(H,40,45)(H4,36,37,38)/t25-,26+,27-,28-/m0/s1 ZGMMELMXTXTHBD-PUHABZHSSA-N 50399636 CHEMBL2181193 Mu-type opioid receptor Cavia cutleri 1.45 ChEMBL 10.1021/jm3008079 10.7270/Q2TM7C82 23102273 Novoa, A; Van Dorpe, S; Wynendaele, E; Spetea, M; Bracke, N; Stalmans, S; Betti, C; Chung, NN; Lemieux, C; Zuegg, J; Cooper, MA; Tourwe, D; De Spiegeleer, B; Schiller, PW; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50399636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50399636&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71462783 163348660 CHEMBL2181193 ZINC95578094 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50974521 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H]1Cc2ccccc2CN([C@@H](CCCCN)C(N)=O)C1=O InChI=1S/C33H49N9O5/c1-19-14-23(43)15-20(2)24(19)17-25(35)30(45)40-26(10-7-13-39-33(37)38)31(46)41-27-16-21-8-3-4-9-22(21)18-42(32(27)47)28(29(36)44)11-5-6-12-34/h3-4,8-9,14-15,25-28,43H,5-7,10-13,16-18,34-35H2,1-2H3,(H2,36,44)(H,40,45)(H,41,46)(H4,37,38,39)/t25-,26+,27-,28-/m0/s1 RGAXFJCJARXKLB-PUHABZHSSA-N 50399644 CHEMBL2181194 Mu-type opioid receptor Cavia cutleri 76 ChEMBL 10.1021/jm3008079 10.7270/Q2TM7C82 23102273 Novoa, A; Van Dorpe, S; Wynendaele, E; Spetea, M; Bracke, N; Stalmans, S; Betti, C; Chung, NN; Lemieux, C; Zuegg, J; Cooper, MA; Tourwe, D; De Spiegeleer, B; Schiller, PW; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50399644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50399644&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71455627 163348668 CHEMBL2181194 ZINC95575662 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50974522 CCCC[C@H](N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CCCNC(N)=O)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(N)=O InChI=1S/C33H49N7O6/c1-5-6-14-28(29(35)42)40(4)32(45)27(18-22-11-8-7-9-12-22)39-31(44)26(13-10-15-37-33(36)46)38-30(43)25(34)19-24-20(2)16-23(41)17-21(24)3/h7-9,11-12,16-17,25-28,41H,5-6,10,13-15,18-19,34H2,1-4H3,(H2,35,42)(H,38,43)(H,39,44)(H3,36,37,46)/t25-,26+,27-,28-/m0/s1 BMDMUFZZAIYXAL-PUHABZHSSA-N 50399637 CHEMBL2181195 Mu-type opioid receptor Cavia cutleri 0.65 ChEMBL 10.1021/jm3008079 10.7270/Q2TM7C82 23102273 Novoa, A; Van Dorpe, S; Wynendaele, E; Spetea, M; Bracke, N; Stalmans, S; Betti, C; Chung, NN; Lemieux, C; Zuegg, J; Cooper, MA; Tourwe, D; De Spiegeleer, B; Schiller, PW; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50399637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50399637&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71453896 163348661 CHEMBL2181195 ZINC95578654 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50974523 CN([C@@H](CCCCN)C(N)=O)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CCCNC(N)=O)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C InChI=1S/C33H50N8O6/c1-20-16-23(42)17-21(2)24(20)19-25(35)30(44)39-26(12-9-15-38-33(37)47)31(45)40-27(18-22-10-5-4-6-11-22)32(46)41(3)28(29(36)43)13-7-8-14-34/h4-6,10-11,16-17,25-28,42H,7-9,12-15,18-19,34-35H2,1-3H3,(H2,36,43)(H,39,44)(H,40,45)(H3,37,38,47)/t25-,26+,27-,28-/m0/s1 BSLACUCHGUNMHO-PUHABZHSSA-N 50399638 CHEMBL2181196 Mu-type opioid receptor Cavia cutleri 1.01 ChEMBL 10.1021/jm3008079 10.7270/Q2TM7C82 23102273 Novoa, A; Van Dorpe, S; Wynendaele, E; Spetea, M; Bracke, N; Stalmans, S; Betti, C; Chung, NN; Lemieux, C; Zuegg, J; Cooper, MA; Tourwe, D; De Spiegeleer, B; Schiller, PW; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50399638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50399638&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71457413 163348662 CHEMBL2181196 ZINC95576960 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50974524 CCCC[C@H](N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(N)=O InChI=1S/C33H50N8O5/c1-5-6-14-28(29(35)43)41(4)32(46)27(18-22-11-8-7-9-12-22)40-31(45)26(13-10-15-38-33(36)37)39-30(44)25(34)19-24-20(2)16-23(42)17-21(24)3/h7-9,11-12,16-17,25-28,42H,5-6,10,13-15,18-19,34H2,1-4H3,(H2,35,43)(H,39,44)(H,40,45)(H4,36,37,38)/t25-,26+,27-,28-/m0/s1 IEAIMVXZKTUXNA-PUHABZHSSA-N 50399639 CHEMBL2181197 Mu-type opioid receptor Cavia cutleri 4.35 ChEMBL 10.1021/jm3008079 10.7270/Q2TM7C82 23102273 Novoa, A; Van Dorpe, S; Wynendaele, E; Spetea, M; Bracke, N; Stalmans, S; Betti, C; Chung, NN; Lemieux, C; Zuegg, J; Cooper, MA; Tourwe, D; De Spiegeleer, B; Schiller, PW; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50399639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50399639&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71459271 163348663 CHEMBL2181197 ZINC95579201 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50974525 CN([C@@H](CCCCN)C(N)=O)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C InChI=1S/C33H51N9O5/c1-20-16-23(43)17-21(2)24(20)19-25(35)30(45)40-26(12-9-15-39-33(37)38)31(46)41-27(18-22-10-5-4-6-11-22)32(47)42(3)28(29(36)44)13-7-8-14-34/h4-6,10-11,16-17,25-28,43H,7-9,12-15,18-19,34-35H2,1-3H3,(H2,36,44)(H,40,45)(H,41,46)(H4,37,38,39)/t25-,26+,27-,28-/m0/s1 HNWCOJUBQHCOIS-PUHABZHSSA-N 50399640 CHEMBL2181198 Mu-type opioid receptor Cavia cutleri 8.3 ChEMBL 10.1021/jm3008079 10.7270/Q2TM7C82 23102273 Novoa, A; Van Dorpe, S; Wynendaele, E; Spetea, M; Bracke, N; Stalmans, S; Betti, C; Chung, NN; Lemieux, C; Zuegg, J; Cooper, MA; Tourwe, D; De Spiegeleer, B; Schiller, PW; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50399640 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50399640&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71462784 163348664 CHEMBL2181198 ZINC95576979 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50974526 CCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CCCNC(N)=O)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(N)=O InChI=1S/C32H47N7O6/c1-4-5-12-25(28(34)41)37-31(44)27(17-21-10-7-6-8-11-21)39-30(43)26(13-9-14-36-32(35)45)38-29(42)24(33)18-23-19(2)15-22(40)16-20(23)3/h6-8,10-11,15-16,24-27,40H,4-5,9,12-14,17-18,33H2,1-3H3,(H2,34,41)(H,37,44)(H,38,42)(H,39,43)(H3,35,36,45)/t24-,25-,26+,27-/m0/s1 LFUXXORPCPSVPB-NFGXINMFSA-N 50399641 CHEMBL2181199 Mu-type opioid receptor Cavia cutleri 0.89 ChEMBL 10.1021/jm3008079 10.7270/Q2TM7C82 23102273 Novoa, A; Van Dorpe, S; Wynendaele, E; Spetea, M; Bracke, N; Stalmans, S; Betti, C; Chung, NN; Lemieux, C; Zuegg, J; Cooper, MA; Tourwe, D; De Spiegeleer, B; Schiller, PW; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50399641 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50399641&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71450248 163348665 CHEMBL2181199 ZINC95571824 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50974527 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C32H48N8O6/c1-19-15-22(41)16-20(2)23(19)18-24(34)29(43)39-26(12-8-14-37-32(36)46)30(44)40-27(17-21-9-4-3-5-10-21)31(45)38-25(28(35)42)11-6-7-13-33/h3-5,9-10,15-16,24-27,41H,6-8,11-14,17-18,33-34H2,1-2H3,(H2,35,42)(H,38,45)(H,39,43)(H,40,44)(H3,36,37,46)/t24-,25-,26+,27-/m0/s1 DFCGTTADNVLUFU-NFGXINMFSA-N 50399642 CHEMBL2181200 Mu-type opioid receptor Cavia cutleri 0.31 ChEMBL 10.1021/jm3008079 10.7270/Q2TM7C82 23102273 Novoa, A; Van Dorpe, S; Wynendaele, E; Spetea, M; Bracke, N; Stalmans, S; Betti, C; Chung, NN; Lemieux, C; Zuegg, J; Cooper, MA; Tourwe, D; De Spiegeleer, B; Schiller, PW; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50399642 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50399642&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71462785 163348666 CHEMBL2181200 ZINC95577495 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50974528 CCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(N)=O InChI=1S/C32H48N8O5/c1-4-5-12-25(28(34)42)38-31(45)27(17-21-10-7-6-8-11-21)40-30(44)26(13-9-14-37-32(35)36)39-29(43)24(33)18-23-19(2)15-22(41)16-20(23)3/h6-8,10-11,15-16,24-27,41H,4-5,9,12-14,17-18,33H2,1-3H3,(H2,34,42)(H,38,45)(H,39,43)(H,40,44)(H4,35,36,37)/t24-,25-,26+,27-/m0/s1 KKWARMPHJUFXQB-NFGXINMFSA-N 50399643 CHEMBL2181201 Mu-type opioid receptor Cavia cutleri 2.2 ChEMBL 10.1021/jm3008079 10.7270/Q2TM7C82 23102273 Novoa, A; Van Dorpe, S; Wynendaele, E; Spetea, M; Bracke, N; Stalmans, S; Betti, C; Chung, NN; Lemieux, C; Zuegg, J; Cooper, MA; Tourwe, D; De Spiegeleer, B; Schiller, PW; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50399643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50399643&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71455628 163348667 CHEMBL2181201 ZINC95577089 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50974529 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C32H49N9O5/c1-19-15-22(42)16-20(2)23(19)18-24(34)29(44)40-26(12-8-14-38-32(36)37)30(45)41-27(17-21-9-4-3-5-10-21)31(46)39-25(28(35)43)11-6-7-13-33/h3-5,9-10,15-16,24-27,42H,6-8,11-14,17-18,33-34H2,1-2H3,(H2,35,43)(H,39,46)(H,40,44)(H,41,45)(H4,36,37,38)/t24-,25-,26+,27-/m0/s1 FIAKHZXVLBNZLW-NFGXINMFSA-N 85731 [Dmt1]DALDA Mu-type opioid receptor Cavia cutleri 1.41 ChEMBL 10.1021/jm3008079 10.7270/Q2TM7C82 23102273 Novoa, A; Van Dorpe, S; Wynendaele, E; Spetea, M; Bracke, N; Stalmans, S; Betti, C; Chung, NN; Lemieux, C; Zuegg, J; Cooper, MA; Tourwe, D; De Spiegeleer, B; Schiller, PW; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85731 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85731&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9809562 136351831 ZINC28470648 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51046512 O=C1N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](Cc2ccccc2)C(=O)N2CCC[C@H]12 InChI=1S/C34H35N5O4/c40-31-27(18-22-10-3-1-4-11-22)37-33(42)30-16-9-17-39(30)34(43)29(19-23-12-5-2-6-13-23)38-32(41)28(36-31)20-24-21-35-26-15-8-7-14-25(24)26/h1-8,10-15,21,27-30,35H,9,16-20H2,(H,36,40)(H,37,42)(H,38,41)/t27-,28-,29-,30+/m0/s1 GIZJWWQFOGQPRY-GCXHJFECSA-N 50268462 CHEMBL506616::c[L-Phe-D-pro-L-Phe-L-trp] Mu-type opioid receptor Cavia cutleri 260 ChEMBL 10.1021/jm301783x 10.7270/Q22808XD 23360448 Carroll, FI; Carlezon, WA Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50268462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50268462&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44583372 104114853 CHEMBL506616 ZINC03989600 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51048940 C[C@@H](NC(=O)C[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](CC(=O)N[C@H](C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(N)=O)Cc1ccc(O)cc1 InChI=1S/C48H59N9O10/c1-29(53-41(60)25-35(49)21-33-13-17-37(58)18-14-33)46(65)52-28-44(63)57-40(24-32-11-7-4-8-12-32)48(67)55-36(22-34-15-19-38(59)20-16-34)26-42(61)54-30(2)47(66)51-27-43(62)56-39(45(50)64)23-31-9-5-3-6-10-31/h3-20,29-30,35-36,39-40,58-59H,21-28,49H2,1-2H3,(H2,50,64)(H,51,66)(H,52,65)(H,53,60)(H,54,61)(H,55,67)(H,56,62)(H,57,63)/t29-,30-,35+,36+,39+,40+/m1/s1 JSXDYCAVWGVFLX-SDOQUPDNSA-N 50428087 CHEMBL2323574 Mu-type opioid receptor Cavia cutleri 670 ChEMBL 10.1021/jm301456c 10.7270/Q2X63P9H 23547584 Mollica, A; Pinnen, F; Costante, R; Locatelli, M; Stefanucci, A; Pieretti, S; Davis, P; Lai, J; Rankin, D; Porreca, F; Hruby, VJ Universit£ di Chieti-Pescara"G. d'Annunzio" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50428087 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50428087&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71720491 164156962 CHEMBL2323574 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51048941 C[C@H](CC(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C)CC(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(N)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C48H59N9O10/c1-29(53-46(65)37(49)23-33-13-17-35(58)18-14-33)21-41(60)52-28-44(63)56-39(25-32-11-7-4-8-12-32)48(67)57-40(26-34-15-19-36(59)20-16-34)47(66)54-30(2)22-42(61)51-27-43(62)55-38(45(50)64)24-31-9-5-3-6-10-31/h3-20,29-30,37-40,58-59H,21-28,49H2,1-2H3,(H2,50,64)(H,51,61)(H,52,60)(H,53,65)(H,54,66)(H,55,62)(H,56,63)(H,57,67)/t29-,30-,37+,38+,39+,40+/m1/s1 AZMWAHGYNUNWBB-KPPTUHEKSA-N 50428088 CHEMBL2323575 Mu-type opioid receptor Cavia cutleri 1700 ChEMBL 10.1021/jm301456c 10.7270/Q2X63P9H 23547584 Mollica, A; Pinnen, F; Costante, R; Locatelli, M; Stefanucci, A; Pieretti, S; Davis, P; Lai, J; Rankin, D; Porreca, F; Hruby, VJ Universit£ di Chieti-Pescara"G. d'Annunzio" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50428088 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50428088&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71718053 164156963 CHEMBL2323575 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51048942 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@H](CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C)C(=O)NCC(=O)N[C@H](CC(N)=O)Cc1ccccc1)Cc1ccccc1 InChI=1S/C48H59N9O10/c1-29(53-47(66)39(49)23-33-13-17-37(58)18-14-33)45(64)51-28-44(63)56-36(22-32-11-7-4-8-12-32)26-42(61)57-40(24-34-15-19-38(59)20-16-34)48(67)54-30(2)46(65)52-27-43(62)55-35(25-41(50)60)21-31-9-5-3-6-10-31/h3-20,29-30,35-36,39-40,58-59H,21-28,49H2,1-2H3,(H2,50,60)(H,51,64)(H,52,65)(H,53,66)(H,54,67)(H,55,62)(H,56,63)(H,57,61)/t29-,30-,35+,36+,39+,40+/m1/s1 GTHUQSLVJIYHHG-SDOQUPDNSA-N 50428089 CHEMBL2323577 Mu-type opioid receptor Cavia cutleri 50 ChEMBL 10.1021/jm301456c 10.7270/Q2X63P9H 23547584 Mollica, A; Pinnen, F; Costante, R; Locatelli, M; Stefanucci, A; Pieretti, S; Davis, P; Lai, J; Rankin, D; Porreca, F; Hruby, VJ Universit£ di Chieti-Pescara"G. d'Annunzio" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50428089 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50428089&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71718671 164156964 CHEMBL2323577 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51048943 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C46H56N10O10/c1-27(51-43(63)35(47)21-31-13-17-33(57)18-14-31)41(61)49-25-39(59)53-37(23-29-9-5-3-6-10-29)45(65)55-56-46(66)38(24-30-11-7-4-8-12-30)54-40(60)26-50-42(62)28(2)52-44(64)36(48)22-32-15-19-34(58)20-16-32/h3-20,27-28,35-38,57-58H,21-26,47-48H2,1-2H3,(H,49,61)(H,50,62)(H,51,63)(H,52,64)(H,53,59)(H,54,60)(H,55,65)(H,56,66)/t27-,28-,35+,36+,37+,38+/m1/s1 DESSEGDLRYOPTJ-VRANXALZSA-N 21014 (2S)-2-amino-N-[(1R)-1-[({[(1S)-1-{N'-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanoyl]hydrazinecarbonyl}-2-phenylethyl]carbamoyl}methyl)carbamoyl]ethyl]-3-(4-hydroxyphenyl)propanamide::(Tyr-Ala-Gly-Phe-NH2)2::Biphalin::CHEMBL200199::bis(Tyr-Ala-Gly-PheNH2)hydrazide::enkephalin dimer Mu-type opioid receptor Cavia cutleri 8.8 ChEMBL 10.1021/jm301456c 10.7270/Q2X63P9H 23547584 Mollica, A; Pinnen, F; Costante, R; Locatelli, M; Stefanucci, A; Pieretti, S; Davis, P; Lai, J; Rankin, D; Porreca, F; Hruby, VJ Universit£ di Chieti-Pescara"G. d'Annunzio" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21014&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5487663 49689087 CHEMBL200199 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51055701 CO[C@]12CC[C@@]3(C[C@@H]1[C@](C)(O)C(C)C)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45 InChI=1S/C28H39NO4/c1-16(2)25(3,31)20-14-26-9-10-28(20,32-4)24-27(26)11-12-29(15-17-5-6-17)21(26)13-18-7-8-19(30)23(33-24)22(18)27/h7-8,16-17,20-21,24,30-31H,5-6,9-15H2,1-4H3/t20-,21-,24-,25-,26-,27+,28-/m1/s1 IORJPTSIJDJGHA-WTOXNGCTSA-N 50430602 CHEMBL2338743 Mu-type opioid receptor Cavia cutleri 0.600000 ChEMBL 10.1021/jm301543e 10.7270/Q28G8N2Q 23438330 Greedy, BM; Bradbury, F; Thomas, MP; Grivas, K; Cami-Kobeci, G; Archambeau, A; Bosse, K; Clark, MJ; Aceto, M; Lewis, JW; Traynor, JR; Husbands, SM University of Bath http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50430602 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50430602&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71624445 164159477 CHEMBL2338743 ZINC95591370 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51055750 CO[C@@]12CC[C@@]3(C[C@@H]1[C@](C)(O)C(C)(C)C)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45 InChI=1S/C29H41NO4/c1-25(2,3)26(4,32)20-15-27-10-11-29(20,33-5)24-28(27)12-13-30(16-17-6-7-17)21(27)14-18-8-9-19(31)23(34-24)22(18)28/h8-9,17,20-21,24,31-32H,6-7,10-16H2,1-5H3/t20-,21-,24-,26+,27-,28+,29+/m1/s1 RMRJXGBAOAMLHD-CTAPUXPBSA-N 50354578 BUPRENORPHINE::US10752592, Compound buprenorphine::US11534436, Compound buprenorphine::US9315514, Buprenorphine Mu-type opioid receptor Cavia cutleri 0.400000 ChEMBL 10.1021/jm301543e 10.7270/Q28G8N2Q 23438330 Greedy, BM; Bradbury, F; Thomas, MP; Grivas, K; Cami-Kobeci, G; Archambeau, A; Bosse, K; Clark, MJ; Aceto, M; Lewis, JW; Traynor, JR; Husbands, SM University of Bath http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354578&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9848990 136361264 C08007 ZINC38321402 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51055751 CCCCC[C@](C)(O)[C@H]1C[C@]23CC[C@]1(OC)[C@@H]1Oc4c5c(C[C@H]2N(CC2CC2)CC[C@@]315)ccc4O InChI=1S/C30H43NO4/c1-4-5-6-11-27(2,33)22-17-28-12-13-30(22,34-3)26-29(28)14-15-31(18-19-7-8-19)23(28)16-20-9-10-21(32)25(35-26)24(20)29/h9-10,19,22-23,26,32-33H,4-8,11-18H2,1-3H3/t22-,23-,26-,27+,28-,29+,30-/m1/s1 NVZMDBQREWGWJI-GVOMISRNSA-N 50430627 CHEMBL2338736 Mu-type opioid receptor Cavia cutleri 2.7 ChEMBL 10.1021/jm301543e 10.7270/Q28G8N2Q 23438330 Greedy, BM; Bradbury, F; Thomas, MP; Grivas, K; Cami-Kobeci, G; Archambeau, A; Bosse, K; Clark, MJ; Aceto, M; Lewis, JW; Traynor, JR; Husbands, SM University of Bath http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50430627 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50430627&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71624893 164159502 CHEMBL2338736 ZINC95587332 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51055752 CCC[C@](C)(O)[C@H]1C[C@]23CC[C@]1(OC)[C@@H]1Oc4c5c(C[C@H]2N(CC2CC2)CC[C@@]315)ccc4O InChI=1S/C28H39NO4/c1-4-9-25(2,31)20-15-26-10-11-28(20,32-3)24-27(26)12-13-29(16-17-5-6-17)21(26)14-18-7-8-19(30)23(33-24)22(18)27/h7-8,17,20-21,24,30-31H,4-6,9-16H2,1-3H3/t20-,21-,24-,25+,26-,27+,28-/m1/s1 UOKRJODYISPCKA-DPJBPYIISA-N 50430603 CHEMBL2338735 Mu-type opioid receptor Cavia cutleri 1.3 ChEMBL 10.1021/jm301543e 10.7270/Q28G8N2Q 23438330 Greedy, BM; Bradbury, F; Thomas, MP; Grivas, K; Cami-Kobeci, G; Archambeau, A; Bosse, K; Clark, MJ; Aceto, M; Lewis, JW; Traynor, JR; Husbands, SM University of Bath http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50430603 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50430603&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71624780 164159478 CHEMBL2338735 ZINC95588148 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51055753 CCCCC[C@@](C)(O)[C@H]1C[C@]23CC[C@]1(OC)[C@@H]1Oc4c5c(C[C@H]2N(CC2CC2)CC[C@@]315)ccc4O InChI=1S/C30H43NO4/c1-4-5-6-11-27(2,33)22-17-28-12-13-30(22,34-3)26-29(28)14-15-31(18-19-7-8-19)23(28)16-20-9-10-21(32)25(35-26)24(20)29/h9-10,19,22-23,26,32-33H,4-8,11-18H2,1-3H3/t22-,23-,26-,27-,28-,29+,30-/m1/s1 NVZMDBQREWGWJI-XELDOGJXSA-N 50430604 CHEMBL2338755 Mu-type opioid receptor Cavia cutleri 2.4 ChEMBL 10.1021/jm301543e 10.7270/Q28G8N2Q 23438330 Greedy, BM; Bradbury, F; Thomas, MP; Grivas, K; Cami-Kobeci, G; Archambeau, A; Bosse, K; Clark, MJ; Aceto, M; Lewis, JW; Traynor, JR; Husbands, SM University of Bath http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50430604 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50430604&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71624664 164159479 CHEMBL2338755 ZINC95586168 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51055754 CCC[C@@](C)(O)[C@H]1C[C@]23CC[C@]1(OC)[C@@H]1Oc4c5c(C[C@H]2N(CC2CC2)CC[C@@]315)ccc4O InChI=1S/C28H39NO4/c1-4-9-25(2,31)20-15-26-10-11-28(20,32-3)24-27(26)12-13-29(16-17-5-6-17)21(26)14-18-7-8-19(30)23(33-24)22(18)27/h7-8,17,20-21,24,30-31H,4-6,9-16H2,1-3H3/t20-,21-,24-,25-,26-,27+,28-/m1/s1 UOKRJODYISPCKA-WTOXNGCTSA-N 50430626 CHEMBL2338754 Mu-type opioid receptor Cavia cutleri 0.900000 ChEMBL 10.1021/jm301543e 10.7270/Q28G8N2Q 23438330 Greedy, BM; Bradbury, F; Thomas, MP; Grivas, K; Cami-Kobeci, G; Archambeau, A; Bosse, K; Clark, MJ; Aceto, M; Lewis, JW; Traynor, JR; Husbands, SM University of Bath http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50430626 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50430626&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71720797 164159501 CHEMBL2338754 ZINC95588234 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50524427 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C28H37N5O7/c1-17(2)12-23(28(39)40)33-27(38)22(14-18-6-4-3-5-7-18)32-25(36)16-30-24(35)15-31-26(37)21(29)13-19-8-10-20(34)11-9-19/h3-11,17,21-23,34H,12-16,29H2,1-2H3,(H,30,35)(H,31,37)(H,32,36)(H,33,38)(H,39,40)/t21-,22-,23-/m0/s1 URLZCHNOLZSCCA-VABKMULXSA-N 50001465 (S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::([Leu]-enkephalin)2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::(enkephalin)2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-1-oxo-3-phenyl-propylamino]-4-methyl-pentanoic acid::2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::2-[1-[1-amino-2-(4-hydroxyphenyl)-(1S)-ethylcarboxamidomethylcarboxamidomethylcarboxamido]-2-phenyl-(1S)-ethylcarboxamido]-4-methyl-(2S)-pentanoic acid::2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid(Enkephalin)::2-{1-[1-amino-2-(4-hydroxyphenyl)ethylcarboxamidomethylcarboxamidomethylcarboxamido]-2-phenylethylcarboxamido}-4-methylpentanoic acid::CHEMBL8234::ENKEPHALIN::Leu-ENKEPHALIN::Leu5-Enkephalin::Tyr-Gly-Gly-Phe-Leu-OH Mu-type opioid receptor Cavia cutleri 246 ChEMBL 10.1021/acs.jmedchem.6b01200 10.7270/Q23B623F 27676089 Weltrowska, G; Nguyen, TM; Chung, NN; Wood, J; Ma, X; Guo, J; Wilkes, BC; Ge, Y; Laferrière, A; Coderre, TJ; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001465&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 461776 103915930 CHEMBL8234 ZINC14952116 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50524428 Cc1cc(O)cc(C)c1CC(N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C32H49N9O5/c1-19-15-22(42)16-20(2)23(19)18-24(34)29(44)40-26(12-8-14-38-32(36)37)30(45)41-27(17-21-9-4-3-5-10-21)31(46)39-25(28(35)43)11-6-7-13-33/h3-5,9-10,15-16,24-27,42H,6-8,11-14,17-18,33-34H2,1-2H3,(H2,35,43)(H,39,46)(H,40,44)(H,41,45)(H4,36,37,38)/t24?,25-,26+,27-/m0/s1 FIAKHZXVLBNZLW-ZAEYVGPMSA-N 50198757 CHEMBL363142 Mu-type opioid receptor Cavia cutleri 1.4 ChEMBL 10.1021/acs.jmedchem.6b01200 10.7270/Q23B623F 27676089 Weltrowska, G; Nguyen, TM; Chung, NN; Wood, J; Ma, X; Guo, J; Wilkes, BC; Ge, Y; Laferrière, A; Coderre, TJ; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50198757 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50198757&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44399140 375978371 CHEMBL363142 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50524449 Cc1cc(O)cc(C)c1C[C@@H]1NCC(CCCCN)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](CCCNC(N)=N)NC1=O InChI=1S/C32H48N8O4/c1-20-15-24(41)16-21(2)25(20)18-27-30(43)39-26(12-8-14-36-32(34)35)29(42)40-28(17-22-9-4-3-5-10-22)31(44)38-23(19-37-27)11-6-7-13-33/h3-5,9-10,15-16,23,26-28,37,41H,6-8,11-14,17-19,33H2,1-2H3,(H,38,44)(H,39,43)(H,40,42)(H4,34,35,36)/t23?,26-,27+,28+/m1/s1 UJYAQIFFOMZKFU-KFFZLYEBSA-N 50198759 CHEMBL3904924 Mu-type opioid receptor Cavia cutleri 2510 ChEMBL 10.1021/acs.jmedchem.6b01200 10.7270/Q23B623F 27676089 Weltrowska, G; Nguyen, TM; Chung, NN; Wood, J; Ma, X; Guo, J; Wilkes, BC; Ge, Y; Laferrière, A; Coderre, TJ; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50198759 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50198759&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 134134942 375978373 CHEMBL3904924 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50599752 CC1C2Cc3ccc(O)cc3C1(C)CC(C#N)N2C InChI=1S/C16H20N2O/c1-10-15-6-11-4-5-13(19)7-14(11)16(10,2)8-12(9-17)18(15)3/h4-5,7,10,12,15,19H,6,8H2,1-3H3 DDJOYOMHKDFQJK-UHFFFAOYSA-N 50028653 (+)-8-Hydroxy-3,6,11-trimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-4-carbonitrile::(-)-8-Hydroxy-3,6,11-trimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-4-carbonitrile::CHEMBL441776 Mu-type opioid receptor Cavia cutleri 510 ChEMBL 10.1021/jm00354a006 10.7270/Q2NG4R56 7154002 Ramakrishnan, K; Portoghese, PS TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028653 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028653&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44280763 103937857 CHEMBL441776 ZINC38148506 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50581703 C[C@H]1C2Cc3ccc(NCc4ccccc4)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C25H32N2/c1-18-24-14-21-10-11-22(26-16-19-6-4-3-5-7-19)15-23(21)25(18,2)12-13-27(24)17-20-8-9-20/h3-7,10-11,15,18,20,24,26H,8-9,12-14,16-17H2,1-2H3/t18-,24?,25-/m0/s1 BZXKIAFEGKPVMG-VNYPPZAHSA-N 50085021 Benzyl-((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-amine::Benzyl-(3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-amine::Benzyl-(3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-amine.2HCl::CHEMBL301835 Mu-type opioid receptor Cavia cutleri 1.5 ChEMBL 10.1016/s0960-894x(99)00670-8 10.7270/Q2571CH7 10673107 Wentland, MP; Xu, G; Cioffi, CL; Ye, Y; Duan, W; Cohen, DJ; Colasurdo, AM; Bidlack, JM Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085021&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10473705 103984504 CHEMBL301835 ZINC13493431 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50581704 C[C@H]1[C@H]2Cc3ccc(Nc4ccccc4)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C24H30N2/c1-17-23-14-19-10-11-21(25-20-6-4-3-5-7-20)15-22(19)24(17,2)12-13-26(23)16-18-8-9-18/h3-7,10-11,15,17-18,23,25H,8-9,12-14,16H2,1-2H3/t17-,23+,24-/m0/s1 FUMBLBJFVJXVBV-VWMXVWASSA-N 50369586 CHEMBL326516 Mu-type opioid receptor Cavia cutleri 1.10 ChEMBL 10.1016/s0960-894x(99)00670-8 10.7270/Q2571CH7 10673107 Wentland, MP; Xu, G; Cioffi, CL; Ye, Y; Duan, W; Cohen, DJ; Colasurdo, AM; Bidlack, JM Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369586 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369586&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73351393 160848688 CHEMBL326516 ZINC13493417 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50581705 C[C@H]1[C@H]2Cc3ccc(Nc4ccccc4)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C24H30N2/c1-17-23-14-19-10-11-21(25-20-6-4-3-5-7-20)15-22(19)24(17,2)12-13-26(23)16-18-8-9-18/h3-7,10-11,15,17-18,23,25H,8-9,12-14,16H2,1-2H3/t17-,23+,24-/m0/s1 FUMBLBJFVJXVBV-VWMXVWASSA-N 50369586 CHEMBL326516 Mu-type opioid receptor Cavia cutleri 1.1 ChEMBL 10.1016/s0960-894x(99)00670-8 10.7270/Q2571CH7 10673107 Wentland, MP; Xu, G; Cioffi, CL; Ye, Y; Duan, W; Cohen, DJ; Colasurdo, AM; Bidlack, JM Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369586 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369586&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73351393 160848688 CHEMBL326516 ZINC13493417 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50581706 C[C@H]1C2Cc3ccc(N)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C18H26N2/c1-12-17-9-14-5-6-15(19)10-16(14)18(12,2)7-8-20(17)11-13-3-4-13/h5-6,10,12-13,17H,3-4,7-9,11,19H2,1-2H3/t12-,17?,18-/m0/s1 STNPURITMRUHGJ-PEYLTSRESA-N 50085024 (6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ylamine::3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ylamine::3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ylamine.2HCl::CHEMBL52399 Mu-type opioid receptor Cavia cutleri 1.80 ChEMBL 10.1016/s0960-894x(99)00670-8 10.7270/Q2571CH7 10673107 Wentland, MP; Xu, G; Cioffi, CL; Ye, Y; Duan, W; Cohen, DJ; Colasurdo, AM; Bidlack, JM Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085024&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44298187 103984507 CHEMBL52399 ZINC13493410 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50581707 C[C@H]1C2Cc3ccc(N)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C18H26N2/c1-12-17-9-14-5-6-15(19)10-16(14)18(12,2)7-8-20(17)11-13-3-4-13/h5-6,10,12-13,17H,3-4,7-9,11,19H2,1-2H3/t12-,17?,18-/m0/s1 STNPURITMRUHGJ-PEYLTSRESA-N 50085024 (6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ylamine::3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ylamine::3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ylamine.2HCl::CHEMBL52399 Mu-type opioid receptor Cavia cutleri 780 ChEMBL 10.1016/s0960-894x(99)00670-8 10.7270/Q2571CH7 10673107 Wentland, MP; Xu, G; Cioffi, CL; Ye, Y; Duan, W; Cohen, DJ; Colasurdo, AM; Bidlack, JM Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085024&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44298187 103984507 CHEMBL52399 ZINC13493410 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50573083 CC1CN(C)CCC11COc2c1cccc2O InChI=1S/C14H19NO2/c1-10-8-15(2)7-6-14(10)9-17-13-11(14)4-3-5-12(13)16/h3-5,10,16H,6-9H2,1-2H3 BQENLWFUKSDROS-UHFFFAOYSA-N 50070946 1',3'-dimethylspiro[2,3-dihydrobenzo[b]furan-3,4'-(hexahydropyridine)]-7-ol::CHEMBL300689 Mu-type opioid receptor Cavia cutleri 1010 ChEMBL 10.1016/s0960-894x(98)00318-7 10.7270/Q2K073D5 9873439 Tsai, YC; Liou, JP; Liao, R; Cheng, CY; Tao, PL National Taiwan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070946&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44296512 103964754 CHEMBL300689 ZINC29481392 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50008184 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NC1CCNc2ccc(Cc3ccccc3)cc12 InChI=1S/C27H31N3O2/c1-17-12-21(31)13-18(2)22(17)16-24(28)27(32)30-26-10-11-29-25-9-8-20(15-23(25)26)14-19-6-4-3-5-7-19/h3-9,12-13,15,24,26,29,31H,10-11,14,16,28H2,1-2H3,(H,30,32)/t24-,26?/m0/s1 VTFUYBNMSGPAQU-QSAPEBAKSA-N 50071865 (S)-2-Amino-N-(6-benzyl-1,2,3,4-tetrahydro-quinolin-4-yl)-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionamide::CHEMBL432045 Mu-type opioid receptor Cavia cutleri 2.62 ChEMBL 10.1016/s0960-894x(98)00472-7 10.7270/Q2154HJJ 9873603 Wang, C; McFadyen, IJ; Traynor, JR; Mosberg, HI University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071865&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323614 103965575 CHEMBL432045 ZINC26646700 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010300 CN([C@H]1CC[C@@]2(CCCO2)C[C@@H]1N1CCCC1)C(=O)Cc1ccccc1 InChI=1S/C22H32N2O2/c1-23(21(25)16-18-8-3-2-4-9-18)19-10-12-22(11-7-15-26-22)17-20(19)24-13-5-6-14-24/h2-4,8-9,19-20H,5-7,10-17H2,1H3/t19-,20-,22-/m0/s1 PGZRDDYTKFZSFR-ONTIZHBOSA-N 21130 N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl)-1-oxaspiro[4.5]decan-8-yl]acetamide::N-methyl-N-(7-(1-pyrrolidinyl)-1-oxaspiro(4,5)dec-8-yl)benzeneacetamide::U-69593::U69,593::[3H]U69593 Mu-type opioid receptor Cavia cutleri 684 ChEMBL 10.1016/s0960-894x(99)00525-9 10.7270/Q28916BJ 10571174 Thomas, JB; Herault, XM; Rothman, RB; Burgess, JP; Mascarella, SW; Xu, H; Horel, RB; Dersch, CM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21130&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 105104 49689203 73357 1655 ZINC02517042 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010308 CCN(CC)C(=O)c1ccc(cc1)N([C@H]1CCN(CC=C)CC1C)c1ccccc1 InChI=1S/C26H35N3O/c1-5-18-27-19-17-25(21(4)20-27)29(23-11-9-8-10-12-23)24-15-13-22(14-16-24)26(30)28(6-2)7-3/h5,8-16,21,25H,1,6-7,17-20H2,2-4H3/t21?,25-/m0/s1 DZIVFTSZIVQCKX-QBGQUKIHSA-N 50082339 4-[((S)-1-Allyl-3-methyl-piperidin-4-yl)-phenyl-amino]-N,N-diethyl-benzamide::CHEMBL430475 Mu-type opioid receptor Cavia cutleri 3500 ChEMBL 10.1016/s0960-894x(99)00525-9 10.7270/Q28916BJ 10571174 Thomas, JB; Herault, XM; Rothman, RB; Burgess, JP; Mascarella, SW; Xu, H; Horel, RB; Dersch, CM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082339 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082339&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44334383 103982142 CHEMBL430475 ZINC13862297 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010309 CN([C@H]1CC[C@@]2(CCCO2)C[C@@H]1N1CCCC1)C(=O)Cc1ccccc1 InChI=1S/C22H32N2O2/c1-23(21(25)16-18-8-3-2-4-9-18)19-10-12-22(11-7-15-26-22)17-20(19)24-13-5-6-14-24/h2-4,8-9,19-20H,5-7,10-17H2,1H3/t19-,20-,22-/m0/s1 PGZRDDYTKFZSFR-ONTIZHBOSA-N 21130 N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl)-1-oxaspiro[4.5]decan-8-yl]acetamide::N-methyl-N-(7-(1-pyrrolidinyl)-1-oxaspiro(4,5)dec-8-yl)benzeneacetamide::U-69593::U69,593::[3H]U69593 Mu-type opioid receptor Cavia cutleri 2142 ChEMBL 10.1016/s0960-894x(99)00525-9 10.7270/Q28916BJ 10571174 Thomas, JB; Herault, XM; Rothman, RB; Burgess, JP; Mascarella, SW; Xu, H; Horel, RB; Dersch, CM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21130&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 105104 49689203 73357 1655 ZINC02517042 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010311 CCN(CC)C(=O)c1ccc(cc1)[C@@H](N1C[C@@H](C)N(CC=C)C[C@@H]1C)c1cccc(OC)c1 InChI=1S/C28H39N3O2/c1-7-17-30-19-22(5)31(20-21(30)4)27(25-11-10-12-26(18-25)33-6)23-13-15-24(16-14-23)28(32)29(8-2)9-3/h7,10-16,18,21-22,27H,1,8-9,17,19-20H2,2-6H3/t21-,22+,27-/m1/s1 KQWVAUSXZDRQPZ-UMTXDNHDSA-N 50039029 (+)-4-((alpha R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-methoxyphenyl)methyl)-N,N-diethylbenzamide::(+)-4-[(alpha-R)-alpha-[2S,5R]-4-allyl[2,5-dimethyl-1-piperazinyl]-3-methoxybenzyl]-N,N-diethylbenzamide::3-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(4-diethylcarbamoyl-phenyl)-methyl]-benzoic acid::4-((R)-((2R,5S)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-methoxyphenyl)methyl)-N,N-diethylbenzamide::4-((R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-methoxyphenyl)methyl)-N,N-diethylbenzamide::4-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide (SNC 80)::4-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide(SNC-80)::4-[(R)-((2R,5S)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-((R)-4-(S)-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-[(2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl](3-methoxyphenyl)-methyl]-N,N-diethylbenzamide::CHEMBL13470::SNC-80 Mu-type opioid receptor Cavia cutleri 317 ChEMBL 10.1016/s0960-894x(99)00525-9 10.7270/Q28916BJ 10571174 Thomas, JB; Herault, XM; Rothman, RB; Burgess, JP; Mascarella, SW; Xu, H; Horel, RB; Dersch, CM; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039029&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 123924 103946292 CHEMBL13470 1611 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015266 Oc1ccc2C[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CC3)c2c1 InChI=1S/C20H27NO/c22-16-7-6-15-11-19-17-3-1-2-8-20(17,18(15)12-16)9-10-21(19)13-14-4-5-14/h6-7,12,14,17,19,22H,1-5,8-11,13H2/t17-,19+,20+/m0/s1 NLBUEDSBXVNAPB-DFQSSKMNSA-N 50135800 (-)-3-Hydroxy-N-cycloproypylmethylmorphinan Mandelate::17-cyclopropylmethyl-(1R,9R,10R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol::3-Hydroxy-N-cyclopropylmethylmorphinan::CHEMBL49269::CYCLORPHAN::US10231963, Table B.6::US10736890, Compound TABLE B.6::US11534436, Compound Table B.6::US9656961, Example 00123 Mu-type opioid receptor Cavia cutleri 0.092000 ChEMBL 10.1016/s0960-894x(01)00543-1 10.7270/Q25T3M01 11591513 Neumeyer, JL; Gu, XH; van Vliet, LA; DeNunzio, NJ; Rusovici, DE; Cohen, DJ; Negus, SS; Mello, NK; Bidlack, JM Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50135800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50135800&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5359966 104026150 CHEMBL49269 ZINC04215487 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015336 Oc1ccc2C[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CCC3)c2c1 InChI=1S/C21H29NO/c23-17-8-7-16-12-20-18-6-1-2-9-21(18,19(16)13-17)10-11-22(20)14-15-4-3-5-15/h7-8,13,15,18,20,23H,1-6,9-12,14H2/t18-,20+,21+/m0/s1 YSTAPDGDOHWKQR-CEWLAPEOSA-N 50135808 (-)-3-Hydroxy-N-cyclobutylmethylmorphinan S(+)-Mandelate::17-cyclobutylmethyl-(1R,9R,10R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol::3-Hydroxy-N-cyclobutylmethylmorphinan::BUTORPHAN::CHEMBL301160::MCL-101 Mu-type opioid receptor Cavia cutleri 0.120000 ChEMBL 10.1016/s0960-894x(01)00543-1 10.7270/Q25T3M01 11591513 Neumeyer, JL; Gu, XH; van Vliet, LA; DeNunzio, NJ; Rusovici, DE; Cohen, DJ; Negus, SS; Mello, NK; Bidlack, JM Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50135808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50135808&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9804450 104026158 CHEMBL301160 ZINC03982790 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010529 CN([C@H]1CC[C@@]2(CCCO2)C[C@@H]1N1CCCC1)C(=O)Cc1ccccc1 InChI=1S/C22H32N2O2/c1-23(21(25)16-18-8-3-2-4-9-18)19-10-12-22(11-7-15-26-22)17-20(19)24-13-5-6-14-24/h2-4,8-9,19-20H,5-7,10-17H2,1H3/t19-,20-,22-/m0/s1 PGZRDDYTKFZSFR-ONTIZHBOSA-N 21130 N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl)-1-oxaspiro[4.5]decan-8-yl]acetamide::N-methyl-N-(7-(1-pyrrolidinyl)-1-oxaspiro(4,5)dec-8-yl)benzeneacetamide::U-69593::U69,593::[3H]U69593 Mu-type opioid receptor Cavia cutleri 684 ChEMBL 10.1016/s0960-894x(99)00613-7 10.7270/Q2MK6DDP 10612597 Thomas, JB; Atkinson, RN; Herault, XM; Rothman, RB; Mascarella, SW; Dersch, CM; Xu, H; Horel, RB; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21130&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 105104 49689203 73357 1655 ZINC02517042 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010557 CCN(CC)C(=O)c1ccc(cc1)N(C1CCN(CC=C)CC1C)c1ccccc1 InChI=1S/C26H35N3O/c1-5-18-27-19-17-25(21(4)20-27)29(23-11-9-8-10-12-23)24-15-13-22(14-16-24)26(30)28(6-2)7-3/h5,8-16,21,25H,1,6-7,17-20H2,2-4H3 DZIVFTSZIVQCKX-UHFFFAOYSA-N 50083636 4-[(1-Allyl-3-methyl-piperidin-4-yl)-phenyl-amino]-N,N-diethyl-benzamide::CHEMBL115730 Mu-type opioid receptor Cavia cutleri 4667 ChEMBL 10.1016/s0960-894x(99)00613-7 10.7270/Q2MK6DDP 10612597 Thomas, JB; Atkinson, RN; Herault, XM; Rothman, RB; Mascarella, SW; Dersch, CM; Xu, H; Horel, RB; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083636&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 22475272 103983282 CHEMBL115730 ZINC13862297 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010560 CCN(CC)C(=O)c1ccc(cc1)[C@@H](N1C[C@@H](C)N(CC=C)C[C@@H]1C)c1cccc(OC)c1 InChI=1S/C28H39N3O2/c1-7-17-30-19-22(5)31(20-21(30)4)27(25-11-10-12-26(18-25)33-6)23-13-15-24(16-14-23)28(32)29(8-2)9-3/h7,10-16,18,21-22,27H,1,8-9,17,19-20H2,2-6H3/t21-,22+,27-/m1/s1 KQWVAUSXZDRQPZ-UMTXDNHDSA-N 50039029 (+)-4-((alpha R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-methoxyphenyl)methyl)-N,N-diethylbenzamide::(+)-4-[(alpha-R)-alpha-[2S,5R]-4-allyl[2,5-dimethyl-1-piperazinyl]-3-methoxybenzyl]-N,N-diethylbenzamide::3-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(4-diethylcarbamoyl-phenyl)-methyl]-benzoic acid::4-((R)-((2R,5S)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-methoxyphenyl)methyl)-N,N-diethylbenzamide::4-((R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-methoxyphenyl)methyl)-N,N-diethylbenzamide::4-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide (SNC 80)::4-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide(SNC-80)::4-[(R)-((2R,5S)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-((R)-4-(S)-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-methoxy-phenyl)-methyl]-N,N-diethyl-benzamide::4-[(R)-[(2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl](3-methoxyphenyl)-methyl]-N,N-diethylbenzamide::CHEMBL13470::SNC-80 Mu-type opioid receptor Cavia cutleri 673 ChEMBL 10.1016/s0960-894x(99)00613-7 10.7270/Q2MK6DDP 10612597 Thomas, JB; Atkinson, RN; Herault, XM; Rothman, RB; Mascarella, SW; Dersch, CM; Xu, H; Horel, RB; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039029&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 123924 103946292 CHEMBL13470 1611 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010571 CN([C@H]1CC[C@@]2(CCCO2)C[C@@H]1N1CCCC1)C(=O)Cc1ccccc1 InChI=1S/C22H32N2O2/c1-23(21(25)16-18-8-3-2-4-9-18)19-10-12-22(11-7-15-26-22)17-20(19)24-13-5-6-14-24/h2-4,8-9,19-20H,5-7,10-17H2,1H3/t19-,20-,22-/m0/s1 PGZRDDYTKFZSFR-ONTIZHBOSA-N 21130 N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl)-1-oxaspiro[4.5]decan-8-yl]acetamide::N-methyl-N-(7-(1-pyrrolidinyl)-1-oxaspiro(4,5)dec-8-yl)benzeneacetamide::U-69593::U69,593::[3H]U69593 Mu-type opioid receptor Cavia cutleri 2142 ChEMBL 10.1016/s0960-894x(99)00613-7 10.7270/Q2MK6DDP 10612597 Thomas, JB; Atkinson, RN; Herault, XM; Rothman, RB; Mascarella, SW; Dersch, CM; Xu, H; Horel, RB; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21130&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 105104 49689203 73357 1655 ZINC02517042 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50010597 CCN(CC)C(=O)c1ccc(cc1)N([C@H]1CCN(CC=C)C[C@H]1C)c1ccccc1 InChI=1S/C26H35N3O/c1-5-18-27-19-17-25(21(4)20-27)29(23-11-9-8-10-12-23)24-15-13-22(14-16-24)26(30)28(6-2)7-3/h5,8-16,21,25H,1,6-7,17-20H2,2-4H3/t21-,25+/m1/s1 DZIVFTSZIVQCKX-BWKNWUBXSA-N 50082341 4-[((3R,4S)-1-Allyl-3-methyl-piperidin-4-yl)-phenyl-amino]-N,N-diethyl-benzamide::CHEMBL102497 Mu-type opioid receptor Cavia cutleri 1782 ChEMBL 10.1016/s0960-894x(99)00613-7 10.7270/Q2MK6DDP 10612597 Thomas, JB; Atkinson, RN; Herault, XM; Rothman, RB; Mascarella, SW; Dersch, CM; Xu, H; Horel, RB; Carroll, FI Research Triangle Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082341&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9887566 103982144 CHEMBL102497 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50582606 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(N)=O InChI=1S/C21H25N3O3/c1-12-7-16(25)8-13(2)17(12)10-18(22)21(27)24-11-15-6-4-3-5-14(15)9-19(24)20(23)26/h3-8,18-19,25H,9-11,22H2,1-2H3,(H2,23,26)/t18-,19?/m0/s1 RXAGYENDHOXBOY-OYKVQYDMSA-N 50060073 2-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid amide::2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid amide::2-[2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-(2S)-propanoyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide::CHEMBL93041 Mu-type opioid receptor Cavia cutleri <10000 ChEMBL 10.1016/s0960-894x(00)00569-2 10.7270/Q25H7HF1 11133082 Santagada, V; Balboni, G; Caliendo, G; Guerrini, R; Salvadori, S; Bianchi, C; Bryant, SD; Lazarus, LH University of Naples http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060073&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325541 103955845 CHEMBL93041 ZINC26660520 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50582607 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1COCc1ccccc1 InChI=1S/C28H32N2O3/c1-19-12-25(31)13-20(2)26(19)15-27(29)28(32)30-16-23-11-7-6-10-22(23)14-24(30)18-33-17-21-8-4-3-5-9-21/h3-13,24,27,31H,14-18,29H2,1-2H3/t24-,27-/m0/s1 ZTQQXSLWESVZAR-IGKIAQTJSA-N 50101612 2-Amino-1-(3-benzyloxymethyl-3,4-dihydro-1H-isoquinolin-2-yl)-3-(4-hydroxy-2,6-dimethyl-phenyl)-propan-1-one::CHEMBL76089 Mu-type opioid receptor Cavia cutleri 525 ChEMBL 10.1016/s0960-894x(00)00569-2 10.7270/Q25H7HF1 11133082 Santagada, V; Balboni, G; Caliendo, G; Guerrini, R; Salvadori, S; Bianchi, C; Bryant, SD; Lazarus, LH University of Naples http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101612 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101612&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11091522 103998249 CHEMBL76089 ZINC13863361 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50582608 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCc2ccc(cc2C1)[N+]([O-])=O InChI=1S/C20H23N3O4/c1-12-7-17(24)8-13(2)18(12)10-19(21)20(25)22-6-5-14-3-4-16(23(26)27)9-15(14)11-22/h3-4,7-9,19,24H,5-6,10-11,21H2,1-2H3/t19-/m0/s1 MDDOOCLODPZQSE-IBGZPJMESA-N 50218552 CHEMBL327381 Mu-type opioid receptor Cavia cutleri 34 ChEMBL 10.1016/s0960-894x(00)00569-2 10.7270/Q25H7HF1 11133082 Santagada, V; Balboni, G; Caliendo, G; Guerrini, R; Salvadori, S; Bianchi, C; Bryant, SD; Lazarus, LH University of Naples http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50218552 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50218552&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325649 376225552 CHEMBL327381 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50582609 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1CO InChI=1S/C21H26N2O3/c1-13-7-18(25)8-14(2)19(13)10-20(22)21(26)23-11-16-6-4-3-5-15(16)9-17(23)12-24/h3-8,17,20,24-25H,9-12,22H2,1-2H3/t17?,20-/m0/s1 HICLVBHTXPRGHR-OZBJMMHXSA-N 50240679 2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-1-(3-hydroxymethyl-3,4-dihydro-1H-isoquinolin-2-yl)-propan-1-one::2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-(3-hydroxymethyl-1,2,3,4-tetrahydro-2-isoquinolinyl)-(2S)-propan-1-one::CHEMBL328135 Mu-type opioid receptor Cavia cutleri <10000 ChEMBL 10.1016/s0960-894x(00)00569-2 10.7270/Q25H7HF1 11133082 Santagada, V; Balboni, G; Caliendo, G; Guerrini, R; Salvadori, S; Bianchi, C; Bryant, SD; Lazarus, LH University of Naples http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240679 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240679&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325612 104098412 CHEMBL328135 ZINC26663734 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50582610 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCc2ccc(O)cc2C1 InChI=1S/C20H24N2O3/c1-12-7-17(24)8-13(2)18(12)10-19(21)20(25)22-6-5-14-3-4-16(23)9-15(14)11-22/h3-4,7-9,19,23-24H,5-6,10-11,21H2,1-2H3/t19-/m0/s1 XMQQCJGFKWYSGJ-IBGZPJMESA-N 50218553 CHEMBL328581 Mu-type opioid receptor Cavia cutleri 6 ChEMBL 10.1016/s0960-894x(00)00569-2 10.7270/Q25H7HF1 11133082 Santagada, V; Balboni, G; Caliendo, G; Guerrini, R; Salvadori, S; Bianchi, C; Bryant, SD; Lazarus, LH University of Naples http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50218553 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50218553&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325569 376225553 CHEMBL328581 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50582611 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCc2ccc(Br)cc2C1 InChI=1S/C20H23BrN2O2/c1-12-7-17(24)8-13(2)18(12)10-19(22)20(25)23-6-5-14-3-4-16(21)9-15(14)11-23/h3-4,7-9,19,24H,5-6,10-11,22H2,1-2H3/t19-/m0/s1 AODUHUQHBSDMHI-IBGZPJMESA-N 50218554 CHEMBL93131 Mu-type opioid receptor Cavia cutleri 18 ChEMBL 10.1016/s0960-894x(00)00569-2 10.7270/Q25H7HF1 11133082 Santagada, V; Balboni, G; Caliendo, G; Guerrini, R; Salvadori, S; Bianchi, C; Bryant, SD; Lazarus, LH University of Naples http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50218554 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50218554&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325588 376225554 CHEMBL93131 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50582612 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCc2ccc(F)cc2C1 InChI=1S/C20H23FN2O2/c1-12-7-17(24)8-13(2)18(12)10-19(22)20(25)23-6-5-14-3-4-16(21)9-15(14)11-23/h3-4,7-9,19,24H,5-6,10-11,22H2,1-2H3/t19-/m0/s1 ILXRQRZSIAELNE-IBGZPJMESA-N 50403820 CHEMBL92707 Mu-type opioid receptor Cavia cutleri 631 ChEMBL 10.1016/s0960-894x(00)00569-2 10.7270/Q25H7HF1 11133082 Santagada, V; Balboni, G; Caliendo, G; Guerrini, R; Salvadori, S; Bianchi, C; Bryant, SD; Lazarus, LH University of Naples http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403820 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403820&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325572 163352844 CHEMBL92707 ZINC26664841 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50582614 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(N)=O InChI=1S/C21H25N3O3/c1-12-7-16(25)8-13(2)17(12)10-18(22)21(27)24-11-15-6-4-3-5-14(15)9-19(24)20(23)26/h3-8,18-19,25H,9-11,22H2,1-2H3,(H2,23,26)/t18-,19?/m0/s1 RXAGYENDHOXBOY-OYKVQYDMSA-N 50060073 2-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid amide::2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid amide::2-[2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-(2S)-propanoyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide::CHEMBL93041 Mu-type opioid receptor Cavia cutleri 277 ChEMBL 10.1016/s0960-894x(00)00569-2 10.7270/Q25H7HF1 11133082 Santagada, V; Balboni, G; Caliendo, G; Guerrini, R; Salvadori, S; Bianchi, C; Bryant, SD; Lazarus, LH University of Naples http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50060073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50060073&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325541 103955845 CHEMBL93041 ZINC26660520 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50582615 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCc2ccc(F)cc2C1 InChI=1S/C20H23FN2O2/c1-12-7-17(24)8-13(2)18(12)10-19(22)20(25)23-6-5-14-3-4-16(21)9-15(14)11-23/h3-4,7-9,19,24H,5-6,10-11,22H2,1-2H3/t19-/m0/s1 ILXRQRZSIAELNE-IBGZPJMESA-N 50403820 CHEMBL92707 Mu-type opioid receptor Cavia cutleri 9 ChEMBL 10.1016/s0960-894x(00)00569-2 10.7270/Q25H7HF1 11133082 Santagada, V; Balboni, G; Caliendo, G; Guerrini, R; Salvadori, S; Bianchi, C; Bryant, SD; Lazarus, LH University of Naples http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403820 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403820&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325572 163352844 CHEMBL92707 ZINC26664841 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50582622 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCc2ccccc2C1 InChI=1S/C20H24N2O2/c1-13-9-17(23)10-14(2)18(13)11-19(21)20(24)22-8-7-15-5-3-4-6-16(15)12-22/h3-6,9-10,19,23H,7-8,11-12,21H2,1-2H3/t19-/m0/s1 CXRZQTPRIWKZAG-IBGZPJMESA-N 50403819 CHEMBL440881 Mu-type opioid receptor Cavia cutleri 490 ChEMBL 10.1016/s0960-894x(00)00569-2 10.7270/Q25H7HF1 11133082 Santagada, V; Balboni, G; Caliendo, G; Guerrini, R; Salvadori, S; Bianchi, C; Bryant, SD; Lazarus, LH University of Naples http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403819 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403819&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325598 163352843 CHEMBL440881 ZINC26651311 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50582623 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCc2ccccc2C1 InChI=1S/C20H24N2O2/c1-13-9-17(23)10-14(2)18(13)11-19(21)20(24)22-8-7-15-5-3-4-6-16(15)12-22/h3-6,9-10,19,23H,7-8,11-12,21H2,1-2H3/t19-/m0/s1 CXRZQTPRIWKZAG-IBGZPJMESA-N 50403819 CHEMBL440881 Mu-type opioid receptor Cavia cutleri 4.6 ChEMBL 10.1016/s0960-894x(00)00569-2 10.7270/Q25H7HF1 11133082 Santagada, V; Balboni, G; Caliendo, G; Guerrini, R; Salvadori, S; Bianchi, C; Bryant, SD; Lazarus, LH University of Naples http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403819 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403819&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325598 163352843 CHEMBL440881 ZINC26651311 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50582624 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1CO InChI=1S/C21H26N2O3/c1-13-7-18(25)8-14(2)19(13)10-20(22)21(26)23-11-16-6-4-3-5-15(16)9-17(23)12-24/h3-8,17,20,24-25H,9-12,22H2,1-2H3/t17?,20-/m0/s1 HICLVBHTXPRGHR-OZBJMMHXSA-N 50240679 2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-1-(3-hydroxymethyl-3,4-dihydro-1H-isoquinolin-2-yl)-propan-1-one::2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-(3-hydroxymethyl-1,2,3,4-tetrahydro-2-isoquinolinyl)-(2S)-propan-1-one::CHEMBL328135 Mu-type opioid receptor Cavia cutleri 151 ChEMBL 10.1016/s0960-894x(00)00569-2 10.7270/Q25H7HF1 11133082 Santagada, V; Balboni, G; Caliendo, G; Guerrini, R; Salvadori, S; Bianchi, C; Bryant, SD; Lazarus, LH University of Naples http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240679 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240679&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325612 104098412 CHEMBL328135 ZINC26663734 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50582625 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1COCc1ccccc1 InChI=1S/C28H32N2O3/c1-19-12-25(31)13-20(2)26(19)15-27(29)28(32)30-16-23-11-7-6-10-22(23)14-24(30)18-33-17-21-8-4-3-5-9-21/h3-13,24,27,31H,14-18,29H2,1-2H3/t24-,27-/m0/s1 ZTQQXSLWESVZAR-IGKIAQTJSA-N 50101612 2-Amino-1-(3-benzyloxymethyl-3,4-dihydro-1H-isoquinolin-2-yl)-3-(4-hydroxy-2,6-dimethyl-phenyl)-propan-1-one::CHEMBL76089 Mu-type opioid receptor Cavia cutleri 6.4 ChEMBL 10.1016/s0960-894x(00)00569-2 10.7270/Q25H7HF1 11133082 Santagada, V; Balboni, G; Caliendo, G; Guerrini, R; Salvadori, S; Bianchi, C; Bryant, SD; Lazarus, LH University of Naples http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101612 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101612&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11091522 103998249 CHEMBL76089 ZINC13863361 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50582626 COc1ccc2CCN(Cc2c1)C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C InChI=1S/C21H26N2O3/c1-13-8-17(24)9-14(2)19(13)11-20(22)21(25)23-7-6-15-4-5-18(26-3)10-16(15)12-23/h4-5,8-10,20,24H,6-7,11-12,22H2,1-3H3/t20-/m0/s1 LUIJDMCTUCNIOG-FQEVSTJZSA-N 50218555 CHEMBL92340 Mu-type opioid receptor Cavia cutleri 18 ChEMBL 10.1016/s0960-894x(00)00569-2 10.7270/Q25H7HF1 11133082 Santagada, V; Balboni, G; Caliendo, G; Guerrini, R; Salvadori, S; Bianchi, C; Bryant, SD; Lazarus, LH University of Naples http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50218555 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50218555&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325619 376225555 CHEMBL92340 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50582627 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccc(F)cc2CC1C(O)=O InChI=1S/C21H23FN2O4/c1-11-5-16(25)6-12(2)17(11)9-18(23)20(26)24-10-13-3-4-15(22)7-14(13)8-19(24)21(27)28/h3-7,18-19,25H,8-10,23H2,1-2H3,(H,27,28)/t18-,19?/m0/s1 BSCMXZDABPTCNN-OYKVQYDMSA-N 50403821 CHEMBL93891 Mu-type opioid receptor Cavia cutleri 813 ChEMBL 10.1016/s0960-894x(00)00569-2 10.7270/Q25H7HF1 11133082 Santagada, V; Balboni, G; Caliendo, G; Guerrini, R; Salvadori, S; Bianchi, C; Bryant, SD; Lazarus, LH University of Naples http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403821 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403821&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11740845 163352845 CHEMBL93891 ZINC26653461 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50582631 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCc2ccc(N)cc2C1 InChI=1S/C20H25N3O2/c1-12-7-17(24)8-13(2)18(12)10-19(22)20(25)23-6-5-14-3-4-16(21)9-15(14)11-23/h3-4,7-9,19,24H,5-6,10-11,21-22H2,1-2H3/t19-/m0/s1 FORXHATWWOAXFB-IBGZPJMESA-N 50218556 CHEMBL93460 Mu-type opioid receptor Cavia cutleri 13 ChEMBL 10.1016/s0960-894x(00)00569-2 10.7270/Q25H7HF1 11133082 Santagada, V; Balboni, G; Caliendo, G; Guerrini, R; Salvadori, S; Bianchi, C; Bryant, SD; Lazarus, LH University of Naples http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50218556 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50218556&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325638 376225556 CHEMBL93460 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50582632 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccc(F)cc2CC1C(O)=O InChI=1S/C21H23FN2O4/c1-11-5-16(25)6-12(2)17(11)9-18(23)20(26)24-10-13-3-4-15(22)7-14(13)8-19(24)21(27)28/h3-7,18-19,25H,8-10,23H2,1-2H3,(H,27,28)/t18-,19?/m0/s1 BSCMXZDABPTCNN-OYKVQYDMSA-N 50403821 CHEMBL93891 Mu-type opioid receptor Cavia cutleri 43.0 ChEMBL 10.1016/s0960-894x(00)00569-2 10.7270/Q25H7HF1 11133082 Santagada, V; Balboni, G; Caliendo, G; Guerrini, R; Salvadori, S; Bianchi, C; Bryant, SD; Lazarus, LH University of Naples http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403821 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403821&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11740845 163352845 CHEMBL93891 ZINC26653461 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50582633 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccc(F)cc2CC1C(O)=O InChI=1S/C21H23FN2O4/c1-11-5-16(25)6-12(2)17(11)9-18(23)20(26)24-10-13-3-4-15(22)7-14(13)8-19(24)21(27)28/h3-7,18-19,25H,8-10,23H2,1-2H3,(H,27,28)/t18-,19?/m0/s1 BSCMXZDABPTCNN-OYKVQYDMSA-N 50403821 CHEMBL93891 Mu-type opioid receptor Cavia cutleri 43 ChEMBL 10.1016/s0960-894x(00)00569-2 10.7270/Q25H7HF1 11133082 Santagada, V; Balboni, G; Caliendo, G; Guerrini, R; Salvadori, S; Bianchi, C; Bryant, SD; Lazarus, LH University of Naples http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403821 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403821&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11740845 163352845 CHEMBL93891 ZINC26653461 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50582634 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O InChI=1S/C40H50N8O10/c1-23(44-37(55)29(41)18-25-9-13-27(50)14-10-25)36(54)46-30(19-24-6-3-2-4-7-24)38(56)43-21-34(52)45-31(20-26-11-15-28(51)16-12-26)40(58)48-17-5-8-33(48)39(57)47-32(22-49)35(42)53/h2-4,6-7,9-16,23,29-33,49-51H,5,8,17-22,41H2,1H3,(H2,42,53)(H,43,56)(H,44,55)(H,45,52)(H,46,54)(H,47,57)/t23-,29+,30+,31+,32+,33+/m1/s1 FHZPGIUBXYVUOY-VWGYHWLBSA-N 50059841 (S)-1-[(S)-2-[2-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid ((S)-1-carbamoyl-2-hydroxy-ethyl)-amide::(S)-2-Amino-N-{(R)-1-[(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethylcarbamoyl]-ethyl}-3-(4-hydroxy-phenyl)-propionamide::1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide::1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide (Dermorphin)::1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide(Dermorphin)::CHEMBL278789::DERMORPHIN::Dermorphin;1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide::H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2::Tyr-Ala-Phe-Gly-Tyr-Pro-Ser::YAFGYPS-NH2 Mu-type opioid receptor Cavia cutleri 1.6 ChEMBL 10.1016/s0960-894x(00)00569-2 10.7270/Q25H7HF1 11133082 Santagada, V; Balboni, G; Caliendo, G; Guerrini, R; Salvadori, S; Bianchi, C; Bryant, SD; Lazarus, LH University of Naples http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059841 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059841&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5485199 103955620 CHEMBL278789 ZINC95548678 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50008768 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H]([C@H](C)c1ccccc1)C(=O)NNC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)[C@H](C)c1ccccc1 InChI=1S/C48H60N10O10/c1-27(33-11-7-5-8-12-33)41(55-39(61)25-51-43(63)29(3)53-45(65)37(49)23-31-15-19-35(59)20-16-31)47(67)57-58-48(68)42(28(2)34-13-9-6-10-14-34)56-40(62)26-52-44(64)30(4)54-46(66)38(50)24-32-17-21-36(60)22-18-32/h5-22,27-30,37-38,41-42,59-60H,23-26,49-50H2,1-4H3,(H,51,63)(H,52,64)(H,53,65)(H,54,66)(H,55,61)(H,56,62)(H,57,67)(H,58,68)/t27-,28-,29-,30-,37+,38+,41+,42+/m1/s1 LBULAXFRDMUFHP-DYFNZJEASA-N 50069562 2-Amino-N-((S)-1-{[((R)-1-{N'-[(R)-2-(2-{(S)-2-[2-amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-acetylamino)-3-phenyl-butyryl]-hydrazinocarbonyl}-2-phenyl-propylcarbamoyl)-methyl]-carbamoyl}-ethyl)-3-(4-hydroxy-phenyl)-propionamide::CHEMBL2371082 Mu-type opioid receptor Cavia cutleri 1.3 ChEMBL 10.1016/s0960-894x(98)00065-1 10.7270/Q2736Q17 9871617 Li, G; Haq, W; Xiang, L; Lou, BS; Hughes, R; De Leon, IA; Davis, P; Gillespie, TJ; Romanowski, M; Zhu, X; Misicka, A; Lipkowski, AW; Porreca, F; Davis, TP; Yamamura, HI; O'Brien, DF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069562 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069562&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73354631 103963622 CHEMBL2371082 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50008769 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H]([C@@H](C)c1ccccc1)C(=O)NNC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)[C@@H](C)c1ccccc1 InChI=1S/C48H60N10O10/c1-27(33-11-7-5-8-12-33)41(55-39(61)25-51-43(63)29(3)53-45(65)37(49)23-31-15-19-35(59)20-16-31)47(67)57-58-48(68)42(28(2)34-13-9-6-10-14-34)56-40(62)26-52-44(64)30(4)54-46(66)38(50)24-32-17-21-36(60)22-18-32/h5-22,27-30,37-38,41-42,59-60H,23-26,49-50H2,1-4H3,(H,51,63)(H,52,64)(H,53,65)(H,54,66)(H,55,61)(H,56,62)(H,57,67)(H,58,68)/t27-,28-,29+,30+,37-,38-,41-,42-/m0/s1 LBULAXFRDMUFHP-SAUILYIYSA-N 50069561 2-Amino-N-((S)-1-{[((S)-1-{N'-[(S)-2-(2-{(S)-2-[2-amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-acetylamino)-3-phenyl-butyryl]-hydrazinocarbonyl}-2-phenyl-propylcarbamoyl)-methyl]-carbamoyl}-ethyl)-3-(4-hydroxy-phenyl)-propionamide::CHEMBL2371081 Mu-type opioid receptor Cavia cutleri 3 ChEMBL 10.1016/s0960-894x(98)00065-1 10.7270/Q2736Q17 9871617 Li, G; Haq, W; Xiang, L; Lou, BS; Hughes, R; De Leon, IA; Davis, P; Gillespie, TJ; Romanowski, M; Zhu, X; Misicka, A; Lipkowski, AW; Porreca, F; Davis, TP; Yamamura, HI; O'Brien, DF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069561 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069561&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73350143 103963621 CHEMBL2371081 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50008776 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1c(F)c(F)c(F)c(F)c1F)C(=O)NNC(=O)[C@H](Cc1c(F)c(F)c(F)c(F)c1F)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C46H46F10N10O10/c1-17(61-43(73)25(57)11-19-3-7-21(67)8-4-19)41(71)59-15-29(69)63-27(13-23-31(47)35(51)39(55)36(52)32(23)48)45(75)65-66-46(76)28(14-24-33(49)37(53)40(56)38(54)34(24)50)64-30(70)16-60-42(72)18(2)62-44(74)26(58)12-20-5-9-22(68)10-6-20/h3-10,17-18,25-28,67-68H,11-16,57-58H2,1-2H3,(H,59,71)(H,60,72)(H,61,73)(H,62,74)(H,63,69)(H,64,70)(H,65,75)(H,66,76)/t17-,18-,25+,26+,27+,28+/m1/s1 GCVFQGNOWGFECF-UWPALRQLSA-N 50069560 Biphalin Analogue::CHEMBL2371080 Mu-type opioid receptor Cavia cutleri 0.910000 ChEMBL 10.1016/s0960-894x(98)00065-1 10.7270/Q2736Q17 9871617 Li, G; Haq, W; Xiang, L; Lou, BS; Hughes, R; De Leon, IA; Davis, P; Gillespie, TJ; Romanowski, M; Zhu, X; Misicka, A; Lipkowski, AW; Porreca, F; Davis, TP; Yamamura, HI; O'Brien, DF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069560 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069560&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73350142 103963620 CHEMBL2371080 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50008777 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)NNC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C54H60N10O10/c1-31(59-51(71)43(55)25-33-13-19-41(65)20-14-33)49(69)57-29-47(67)61-45(27-35-11-17-37-7-3-5-9-39(37)23-35)53(73)63-64-54(74)46(28-36-12-18-38-8-4-6-10-40(38)24-36)62-48(68)30-58-50(70)32(2)60-52(72)44(56)26-34-15-21-42(66)22-16-34/h3-24,31-32,43-46,65-66H,25-30,55-56H2,1-2H3,(H,57,69)(H,58,70)(H,59,71)(H,60,72)(H,61,67)(H,62,68)(H,63,73)(H,64,74)/t31-,32-,43+,44+,45+,46+/m1/s1 XBOROKFRDNQVOY-ATTIMZMDSA-N 50069563 Biphalin Analogue::CHEMBL2371079 Mu-type opioid receptor Cavia cutleri 1.7 ChEMBL 10.1016/s0960-894x(98)00065-1 10.7270/Q2736Q17 9871617 Li, G; Haq, W; Xiang, L; Lou, BS; Hughes, R; De Leon, IA; Davis, P; Gillespie, TJ; Romanowski, M; Zhu, X; Misicka, A; Lipkowski, AW; Porreca, F; Davis, TP; Yamamura, HI; O'Brien, DF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069563&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73345526 103963623 CHEMBL2371079 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50008780 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1cccc2ccccc12)C(=O)NNC(=O)[C@H](Cc1cccc2ccccc12)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C54H60N10O10/c1-31(59-51(71)43(55)25-33-17-21-39(65)22-18-33)49(69)57-29-47(67)61-45(27-37-13-7-11-35-9-3-5-15-41(35)37)53(73)63-64-54(74)46(28-38-14-8-12-36-10-4-6-16-42(36)38)62-48(68)30-58-50(70)32(2)60-52(72)44(56)26-34-19-23-40(66)24-20-34/h3-24,31-32,43-46,65-66H,25-30,55-56H2,1-2H3,(H,57,69)(H,58,70)(H,59,71)(H,60,72)(H,61,67)(H,62,68)(H,63,73)(H,64,74)/t31-,32-,43+,44+,45+,46+/m1/s1 GLZFVTVMXOQFMT-ATTIMZMDSA-N 50069559 Biphalin Analogue::CHEMBL2371057 Mu-type opioid receptor Cavia cutleri 0.790000 ChEMBL 10.1016/s0960-894x(98)00065-1 10.7270/Q2736Q17 9871617 Li, G; Haq, W; Xiang, L; Lou, BS; Hughes, R; De Leon, IA; Davis, P; Gillespie, TJ; Romanowski, M; Zhu, X; Misicka, A; Lipkowski, AW; Porreca, F; Davis, TP; Yamamura, HI; O'Brien, DF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069559 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069559&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9963195 103963619 CHEMBL2371057 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50008782 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C46H56N10O10/c1-27(51-43(63)35(47)21-31-13-17-33(57)18-14-31)41(61)49-25-39(59)53-37(23-29-9-5-3-6-10-29)45(65)55-56-46(66)38(24-30-11-7-4-8-12-30)54-40(60)26-50-42(62)28(2)52-44(64)36(48)22-32-15-19-34(58)20-16-32/h3-20,27-28,35-38,57-58H,21-26,47-48H2,1-2H3,(H,49,61)(H,50,62)(H,51,63)(H,52,64)(H,53,59)(H,54,60)(H,55,65)(H,56,66)/t27-,28+,35-,36-,37-,38-/m0/s1 DESSEGDLRYOPTJ-LWXVJZBWSA-N 50069558 2-Amino-N-((S)-1-{[(2-{N'-[2-(2-{(S)-2-[2-amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-acetylamino)-3-phenyl-propionyl]-hydrazino}-1-benzyl-2-oxo-ethylcarbamoyl)-methyl]-carbamoyl}-ethyl)-3-(4-hydroxy-phenyl)-propionamide::CHEMBL2371056 Mu-type opioid receptor Cavia cutleri 2.8 ChEMBL 10.1016/s0960-894x(98)00065-1 10.7270/Q2736Q17 9871617 Li, G; Haq, W; Xiang, L; Lou, BS; Hughes, R; De Leon, IA; Davis, P; Gillespie, TJ; Romanowski, M; Zhu, X; Misicka, A; Lipkowski, AW; Porreca, F; Davis, TP; Yamamura, HI; O'Brien, DF; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069558&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 134377 103963618 CHEMBL2371056 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50598302 Cl.Cl.Cc1cc(O)cc(C)c1CC(N)C(=O)NCCCc1nc(O)c(CCCNC(=O)C(N)Cc2c(C)cc(O)cc2C)nc1C InChI=1S/C33H46N6O5.2ClH/c1-18-12-23(40)13-19(2)25(18)16-27(34)31(42)36-10-6-8-29-22(5)38-30(33(44)39-29)9-7-11-37-32(43)28(35)17-26-20(3)14-24(41)15-21(26)4;;/h12-15,27-28,40-41H,6-11,16-17,34-35H2,1-5H3,(H,36,42)(H,37,43)(H,39,44);2*1H URYAHBAOOJGMHC-UHFFFAOYSA-N 50221787 CHEMBL3216418 Mu-type opioid receptor Cavia cutleri 1.3 ChEMBL 10.1021/jm0304616 10.7270/Q2RB755V 15115401 Jinsmaa, Y; Miyazaki, A; Fujita, Y; Li, T; Fujisawa, Y; Shiotani, K; Tsuda, Y; Yokoi, T; Ambo, A; Sasaki, Y; Bryant, SD; Lazarus, LH; Okada, Y National Institutes of Environmental Health Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221787&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11204687 377008080 CHEMBL3216418 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50598304 Cl.Cl.Cc1cc(O)cc(C)c1CC(N)C(=O)NCCCCc1nc(O)c(CCCCNC(=O)C(N)Cc2c(C)cc(O)cc2C)nc1C InChI=1S/C35H50N6O5.2ClH/c1-20-14-25(42)15-21(2)27(20)18-29(36)33(44)38-12-8-6-10-31-24(5)40-32(35(46)41-31)11-7-9-13-39-34(45)30(37)19-28-22(3)16-26(43)17-23(28)4;;/h14-17,29-30,42-43H,6-13,18-19,36-37H2,1-5H3,(H,38,44)(H,39,45)(H,41,46);2*1H PYLMQAOYRWPZPF-UHFFFAOYSA-N 50221778 CHEMBL3216392 Mu-type opioid receptor Cavia cutleri 1.9 ChEMBL 10.1021/jm0304616 10.7270/Q2RB755V 15115401 Jinsmaa, Y; Miyazaki, A; Fujita, Y; Li, T; Fujisawa, Y; Shiotani, K; Tsuda, Y; Yokoi, T; Ambo, A; Sasaki, Y; Bryant, SD; Lazarus, LH; Okada, Y National Institutes of Environmental Health Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221778 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221778&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 90664762 377008071 CHEMBL3216392 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50598306 Cl.Cl.Cc1cc(O)cc(C)c1CC(N)C(=O)NCCc1nc(O)c(CCNC(=O)C(N)Cc2c(C)cc(O)cc2C)nc1C InChI=1S/C31H42N6O5.2ClH/c1-16-10-21(38)11-17(2)23(16)14-25(32)29(40)34-8-6-27-20(5)36-28(31(42)37-27)7-9-35-30(41)26(33)15-24-18(3)12-22(39)13-19(24)4;;/h10-13,25-26,38-39H,6-9,14-15,32-33H2,1-5H3,(H,34,40)(H,35,41)(H,37,42);2*1H NRIGZEQNWMHQHG-UHFFFAOYSA-N 50221781 CHEMBL3215968 Mu-type opioid receptor Cavia cutleri 13 ChEMBL 10.1021/jm0304616 10.7270/Q2RB755V 15115401 Jinsmaa, Y; Miyazaki, A; Fujita, Y; Li, T; Fujisawa, Y; Shiotani, K; Tsuda, Y; Yokoi, T; Ambo, A; Sasaki, Y; Bryant, SD; Lazarus, LH; Okada, Y National Institutes of Environmental Health Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221781 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221781&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 90664521 377008074 CHEMBL3215968 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50598313 Cl.Cl.Cc1cc(O)cc(C)c1CC(N)C(=O)NCc1nc(O)c(CNC(=O)C(N)Cc2c(C)cc(O)cc2C)nc1C InChI=1S/C29H38N6O5.2ClH/c1-14-6-19(36)7-15(2)21(14)10-23(30)27(38)32-12-25-18(5)34-26(29(40)35-25)13-33-28(39)24(31)11-22-16(3)8-20(37)9-17(22)4;;/h6-9,23-24,36-37H,10-13,30-31H2,1-5H3,(H,32,38)(H,33,39)(H,35,40);2*1H GPDVNRULAZKNBV-UHFFFAOYSA-N 50221780 CHEMBL3217089 Mu-type opioid receptor Cavia cutleri 1695 ChEMBL 10.1021/jm0304616 10.7270/Q2RB755V 15115401 Jinsmaa, Y; Miyazaki, A; Fujita, Y; Li, T; Fujisawa, Y; Shiotani, K; Tsuda, Y; Yokoi, T; Ambo, A; Sasaki, Y; Bryant, SD; Lazarus, LH; Okada, Y National Institutes of Environmental Health Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221780 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221780&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 90665145 377008073 CHEMBL3217089 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032929 CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(O)=O InChI=1S/C33H46N6O10/c1-18(2)13-24(32(47)39-28(19(3)41)33(48)49)37-31(46)25(15-21-9-11-22(42)12-10-21)36-27(43)16-35-30(45)26(17-40)38-29(44)23(34)14-20-7-5-4-6-8-20/h4-12,18-19,23-26,28,40-42H,13-17,34H2,1-3H3,(H,35,45)(H,36,43)(H,37,46)(H,38,44)(H,39,47)(H,48,49)/t19-,23+,24+,25+,26+,28+/m1/s1 HMJDTHFFUZCTEX-KXJTVXFKSA-N 50013626 2-{2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-3-hydroxy-propionylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methyl-pentanoylamino}-3-hydroxy-butyric acid (DSLET)::CHEMBL47029 Mu-type opioid receptor Cavia cutleri 59 ChEMBL 10.1021/jm00168a028 10.7270/Q27P9003 2160538 Portoghese, PS; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013626 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013626&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44292854 103925723 CHEMBL47029 ZINC29415610 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032937 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1 DQCKKXVULJGBQN-XFWGSAIBSA-N 60212 (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::MLS000069607::NALTREXONE HYDROCHLORIDE::SMR000058767::US10988481, Compound NTX::US9107954, naltrexone::cid_5485201 Mu-type opioid receptor Cavia cutleri 0.800000 ChEMBL 10.1021/jm00168a028 10.7270/Q27P9003 2160538 Portoghese, PS; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60212&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5360515 252639834 DB00704 C07253 ZINC00001773 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032939 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)C(C)(C)NC(=O)C(C)(C)NC(=O)[C@H](Cc1ccc(O)cc1)N(CC=C)CC=C)C(O)=O InChI=1S/C38H53N5O7/c1-9-20-43(21-10-2)31(24-27-16-18-28(44)19-17-27)33(46)41-38(7,8)36(50)42-37(5,6)35(49)40-29(23-26-14-12-11-13-15-26)32(45)39-30(34(47)48)22-25(3)4/h9-19,25,29-31,44H,1-2,20-24H2,3-8H3,(H,39,45)(H,40,49)(H,41,46)(H,42,50)(H,47,48)/t29-,30-,31-/m0/s1 XUWLAGNFLUARAN-CHQNGUEUSA-N 50006946 2-[2-(2-{2-[2-Diallylamino-3-(4-hydroxy-phenyl)-propionylamino]-2-methyl-propionylamino}-2-methyl-propionylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::CHEMBL47545::ICI-174864 Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm00168a028 10.7270/Q27P9003 2160538 Portoghese, PS; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50006946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50006946&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44149909 103920235 CHEMBL47545 ZINC29402878 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032941 Oc1ccc2CC3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1c(C[C@@]35O)c2ccccc2n1-c1ccccc1 InChI=1S/C32H30N2O3/c35-25-13-12-20-16-26-32(36)17-23-22-8-4-5-9-24(22)34(21-6-2-1-3-7-21)28(23)30-31(32,27(20)29(25)37-30)14-15-33(26)18-19-10-11-19/h1-9,12-13,19,26,30,35-36H,10-11,14-18H2/t26?,30-,31-,32+/m0/s1 XZBLPOKMIVGXML-ZCPWPLGKSA-N 50013627 22-cyclopropylmethyl-11-phenyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol(HCl) Mu-type opioid receptor Cavia cutleri 28 ChEMBL 10.1021/jm00168a028 10.7270/Q27P9003 2160538 Portoghese, PS; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013627 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013627&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44292966 103925724 ZINC29405058 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032943 Cn1c2[C@@H]3Oc4c5c(CC6N(CC7CC7)CC[C@@]35[C@@]6(O)Cc2c2ccccc12)ccc4O InChI=1S/C27H28N2O3/c1-28-19-5-3-2-4-17(19)18-13-27(31)21-12-16-8-9-20(30)24-22(16)26(27,25(32-24)23(18)28)10-11-29(21)14-15-6-7-15/h2-5,8-9,15,21,25,30-31H,6-7,10-14H2,1H3/t21?,25-,26-,27+/m0/s1 CRTCCMARDBQOKA-SSNGLDLMSA-N 50013625 22-cyclopropylmethyl-11-methyl-(1S,2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaene-2,16-diol::22-cyclopropylmethyl-11-methyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol(HCl2H2O)::22-cyclopropylmethyl-11-methyl-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaene-2,16-diol Mu-type opioid receptor Cavia cutleri 14 ChEMBL 10.1021/jm00168a028 10.7270/Q27P9003 2160538 Portoghese, PS; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013625 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013625&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44292630 103925722 ZINC13821974 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032947 COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2ccccc2c1C[C@@]35O InChI=1S/C27H28N2O3/c1-31-20-9-8-16-12-21-27(30)13-18-17-4-2-3-5-19(17)28-23(18)25-26(27,22(16)24(20)32-25)10-11-29(21)14-15-6-7-15/h2-5,8-9,15,21,25,28,30H,6-7,10-14H2,1H3/t21-,25+,26+,27-/m1/s1 HKUIBYDTKWHKJU-NVSKSXHLSA-N 50262499 (5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro-4,5-epoxy-3-methoxy-indolo[2',3':6,7]morphinan-14-ol::22-cyclopropylmethyl-16-methoxy-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaen-2-ol(HCl1.5H2O)::CHEMBL514693 Mu-type opioid receptor Cavia cutleri 550 ChEMBL 10.1021/jm00168a028 10.7270/Q27P9003 2160538 Portoghese, PS; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50262499 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50262499&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44578135 104111161 CHEMBL514693 ZINC03808807 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032948 Oc1ccc2C[C@H]3N(CC4CC4)CCC45C(Oc1c24)c1[nH]c2ccccc2c1CC35O InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1 WIYUZYBFCWCCQJ-XEWUMVRVSA-N 21864 (21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.0^{1,13}.0^{2,21}.0^{4,12}.0^{5,10}.0^{19,25}]pentacosa-4(12),5,7,9,15,17,19(25)-heptaene-2,16-diol::(8R)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol::NALTRINDOLE::[3H]-naltrindole Mu-type opioid receptor Cavia cutleri 3.8 ChEMBL 10.1021/jm00168a028 10.7270/Q27P9003 2160538 Portoghese, PS; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21864&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3034754 49700969 ZINC62153992 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032949 Oc1ccc2CC3N(CC=C)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2ccccc2c1C[C@@]35O InChI=1S/C25H24N2O3/c1-2-10-27-11-9-24-20-14-7-8-18(28)22(20)30-23(24)21-16(13-25(24,29)19(27)12-14)15-5-3-4-6-17(15)26-21/h2-8,19,23,26,28-29H,1,9-13H2/t19?,23-,24-,25+/m0/s1 VHOJNKFFCXAXME-DYZJZLFBSA-N 50013621 22-allyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol Mu-type opioid receptor Cavia cutleri 104 ChEMBL 10.1021/jm00168a028 10.7270/Q27P9003 2160538 Portoghese, PS; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013621 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013621&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44292644 103925718 ZINC29408078 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032958 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)Cc1c4[nH]c2ccccc12)ccc5O InChI=1S/C23H22N2O3/c1-25-9-8-22-18-12-6-7-16(26)20(18)28-21(22)19-14(11-23(22,27)17(25)10-12)13-4-2-3-5-15(13)24-19/h2-7,17,21,24,26-27H,8-11H2,1H3/t17-,21+,22+,23-/m1/s1 YQNZUKAKYJMEFE-LMDOGRNLSA-N 50221416 22-methyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol(HCl0.5H2O) (Oxymorphindole, OMI)::22-methyl-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol::CHEMBL401093::OXYMORPHINDOLE Mu-type opioid receptor Cavia cutleri 468 ChEMBL 10.1021/jm00168a028 10.7270/Q27P9003 2160538 Portoghese, PS; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221416 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221416&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5491897 104094073 CHEMBL401093 ZINC05966777 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032962 COc1cccc2c3C[C@@]4(O)C5Cc6ccc(O)c7O[C@@H](c3[nH]c12)[C@]4(CCN5CC1CC1)c67 InChI=1S/C27H28N2O4/c1-32-19-4-2-3-16-17-12-27(31)20-11-15-7-8-18(30)24-21(15)26(27,9-10-29(20)13-14-5-6-14)25(33-24)23(17)28-22(16)19/h2-4,7-8,14,20,25,28,30-31H,5-6,9-13H2,1H3/t20?,25-,26-,27+/m0/s1 UFSBESMXMNBZHB-WINLFKIGSA-N 50013622 9-methyloxy-22-cyclopropylmethyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol(HCl1.5H2O) Mu-type opioid receptor Cavia cutleri 16 ChEMBL 10.1021/jm00168a028 10.7270/Q27P9003 2160538 Portoghese, PS; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013622 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013622&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44292997 103925719 ZINC29417015 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032992 CC(C)(S)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](NC(=O)[C@@H](N)Cc1ccccc1)C(C)(C)S)C(O)=O InChI=1S/C30H41N5O7S2/c1-29(2,43)23(34-25(38)20(31)14-17-8-6-5-7-9-17)27(40)32-16-22(37)33-21(15-18-10-12-19(36)13-11-18)26(39)35-24(28(41)42)30(3,4)44/h5-13,20-21,23-24,36,43-44H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21-,23-,24-/m0/s1 RILFYUXURMDFOY-WMIMKTLMSA-N 50013620 2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-3-mercapto-3-methyl-butyrylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-3-mercapto-3-methyl-butyric acid (DPLPE)::CHEMBL2372782 Mu-type opioid receptor Cavia cutleri 570 ChEMBL 10.1021/jm00168a028 10.7270/Q27P9003 2160538 Portoghese, PS; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013620 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013620&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73348734 103925717 CHEMBL2372782 ZINC29417536 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50032994 Oc1ccc2CC3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2c(Br)cccc2c1C[C@@]35O InChI=1S/C26H25BrN2O3/c27-17-3-1-2-15-16-11-26(31)19-10-14-6-7-18(30)23-20(14)25(26,8-9-29(19)12-13-4-5-13)24(32-23)22(16)28-21(15)17/h1-3,6-7,13,19,24,28,30-31H,4-5,8-12H2/t19?,24-,25-,26+/m0/s1 KXQMACNKPIFADJ-VCCHHJRHSA-N 50013623 9-bromo-22-cyclopropylmethyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol Mu-type opioid receptor Cavia cutleri 29 ChEMBL 10.1021/jm00168a028 10.7270/Q27P9003 2160538 Portoghese, PS; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013623 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013623&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44293065 103925720 ZINC29468503 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50635486 Oc1ccc2CC3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2ccc(F)cc2c1C[C@@]35O InChI=1S/C26H25FN2O3/c27-15-4-5-18-16(10-15)17-11-26(31)20-9-14-3-6-19(30)23-21(14)25(26,24(32-23)22(17)28-18)7-8-29(20)12-13-1-2-13/h3-6,10,13,20,24,28,30-31H,1-2,7-9,11-12H2/t20?,24-,25-,26+/m0/s1 WGXUQUPBNGMMPM-OOGIKFLQSA-N 50013624 22-cyclopropylmethyl-7-fluoro-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol(HCl.1.5H2O)::22-cyclopropylmethyl-7-fluoro-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaene-2,16-diol Mu-type opioid receptor Cavia cutleri 1.7 ChEMBL 10.1021/jm00168a028 10.7270/Q27P9003 2160538 Portoghese, PS; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013624 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013624&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44292764 103925721 ZINC26675145 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50635488 Oc1ccc2CC3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2c(F)cccc2c1C[C@@]35O InChI=1S/C26H25FN2O3/c27-17-3-1-2-15-16-11-26(31)19-10-14-6-7-18(30)23-20(14)25(26,8-9-29(19)12-13-4-5-13)24(32-23)22(16)28-21(15)17/h1-3,6-7,13,19,24,28,30-31H,4-5,8-12H2/t19?,24-,25-,26+/m0/s1 GKAYFPSXBGBKFN-VCCHHJRHSA-N 50013619 9-fluoro-22-cyclopropylmethyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol(HCl1.5H2O) Mu-type opioid receptor Cavia cutleri 49 ChEMBL 10.1021/jm00168a028 10.7270/Q27P9003 2160538 Portoghese, PS; Sultana, M; Takemori, AE University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013619 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013619&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44293021 103925716 ZINC29409287 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50650903 FC(F)(F)c1ccc(CC(=O)N2CCc3ccccc3[C@H]2CN2CCCC2)cc1 InChI=1S/C23H25F3N2O/c24-23(25,26)19-9-7-17(8-10-19)15-22(29)28-14-11-18-5-1-2-6-20(18)21(28)16-27-12-3-4-13-27/h1-2,5-10,21H,3-4,11-16H2/t21-/m1/s1 YOLQXHYBPFPWEI-OAQYLSRUSA-N 50453089 CHEMBL2114225 Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/jm00112a042 10.7270/Q2CV4GPX 1652025 Vecchietti, V; Clarke, GD; Colle, R; Giardina, G; Petrone, G; Sbacchi, M Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453089 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453089&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10069687 225145851 CHEMBL2114225 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50642053 CC(C(=O)N(C)[C@H]1CCCC[C@@H]1N1CCCC1)c1cccc2sccc12 InChI=1S/C22H30N2OS/c1-16(17-8-7-11-21-18(17)12-15-26-21)22(25)23(2)19-9-3-4-10-20(19)24-13-5-6-14-24/h7-8,11-12,15-16,19-20H,3-6,9-10,13-14H2,1-2H3/t16?,19-,20-/m0/s1 UMIAZJFHSCKPMM-RFFXKOPCSA-N 50008851 2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-propionamide; hydrochloride::CHEMBL553114 Mu-type opioid receptor Cavia cutleri 2460 ChEMBL 10.1021/jm00105a028 10.7270/Q2J103SG 1846919 Halfpenny, PR; Horwell, DC; Hughes, J; Humblet, C; Hunter, JC; Neuhaus, D; Rees, DC Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008851&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300829 103921952 CHEMBL553114 ZINC13860895 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50642055 CN([C@H]1CCC2(CCCO2)C[C@@H]1N1CCCC1)C(=O)C1CCc2csc3cccc1c23 InChI=1S/C26H34N2O2S/c1-27(25(29)20-9-8-18-17-31-23-7-4-6-19(20)24(18)23)21-10-12-26(11-5-15-30-26)16-22(21)28-13-2-3-14-28/h4,6-7,17,20-22H,2-3,5,8-16H2,1H3/t20?,21-,22-,26?/m0/s1 MPLOOKCTVWUMQO-UBFBPUDLSA-N 50008855 4,5-Dihydro-3H-naphtho[1,8-bc]thiophene-5-carboxylic acid methyl-(7-pyrrolidin-1-yl-1-oxa-spiro[4.5]dec-8-yl)-amide; compound with toluene-4-sulfonic acid::CHEMBL300831 Mu-type opioid receptor Cavia cutleri 62 ChEMBL 10.1021/jm00105a028 10.7270/Q2J103SG 1846919 Halfpenny, PR; Horwell, DC; Hughes, J; Humblet, C; Hunter, JC; Neuhaus, D; Rees, DC Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008855&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300699 103921956 CHEMBL300831 ZINC29553888 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50642056 CN([C@H]1CCC2(CCCO2)C[C@@H]1N1CCCC1)C(=O)C1CCc2c(Br)sc3cccc1c23 InChI=1S/C26H33BrN2O2S/c1-28(20-10-12-26(11-5-15-31-26)16-21(20)29-13-2-3-14-29)25(30)18-8-9-19-23-17(18)6-4-7-22(23)32-24(19)27/h4,6-7,18,20-21H,2-3,5,8-16H2,1H3/t18?,20-,21-,26?/m0/s1 WPDLVWOUMWRXIF-UGWRYHMVSA-N 50008853 2-Bromo-4,5-dihydro-3H-naphtho[1,8-bc]thiophene-5-carboxylic acid methyl-(7-pyrrolidin-1-yl-1-oxa-spiro[4.5]dec-8-yl)-amide; compound with toluene-4-sulfonic acid::CHEMBL300832 Mu-type opioid receptor Cavia cutleri 170 ChEMBL 10.1021/jm00105a028 10.7270/Q2J103SG 1846919 Halfpenny, PR; Horwell, DC; Hughes, J; Humblet, C; Hunter, JC; Neuhaus, D; Rees, DC Parke-Davis Research Unit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008853&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300701 103921954 CHEMBL300832 ZINC29553895 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50642309 CN1CCCC1C1CCCCN1C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C18H24Cl2N2O/c1-21-9-4-6-16(21)17-5-2-3-10-22(17)18(23)12-13-7-8-14(19)15(20)11-13/h7-8,11,16-17H,2-6,9-10,12H2,1H3 UOAOMCIHXQMCHQ-UHFFFAOYSA-N 50008888 (threo)2-(3,4-Dichloro-phenyl)-1-[2-(1-methyl-pyrrolidin-2-yl)-piperidin-1-yl]-ethanone(HCl)::2-(3,4-Dichloro-phenyl)-1-[2-(1-methyl-pyrrolidin-2-yl)-piperidin-1-yl]-ethanone(HCl)::CHEMBL130272 Mu-type opioid receptor Cavia cutleri 464 ChEMBL 10.1021/jm00105a061 10.7270/Q23777N1 1846921 Vecchietti, V; Giordani, A; Giardina, G; Colle, R; Clarke, GD Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008888&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14810996 103921989 CHEMBL130272 ZINC26260850 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50642312 CC(C1CCCCN1C(=O)Cc1ccc(Cl)c(Cl)c1)N(C)C InChI=1S/C17H24Cl2N2O/c1-12(20(2)3)16-6-4-5-9-21(16)17(22)11-13-7-8-14(18)15(19)10-13/h7-8,10,12,16H,4-6,9,11H2,1-3H3 MJVPVUAVZUCLJO-UHFFFAOYSA-N 50008889 (threo)2-(3,4-Dichloro-phenyl)-1-[2-(1-dimethylamino-ethyl)-piperidin-1-yl]-ethanone(HCl)::2-(3,4-Dichloro-phenyl)-1-[2-(1-dimethylamino-ethyl)-piperidin-1-yl]-ethanone(HCl)::CHEMBL131034 Mu-type opioid receptor Cavia cutleri 762 ChEMBL 10.1021/jm00105a061 10.7270/Q23777N1 1846921 Vecchietti, V; Giordani, A; Giardina, G; Colle, R; Clarke, GD Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008889 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008889&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14810989 103921990 CHEMBL131034 ZINC13884739 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50642314 FC(F)(F)c1ccc(CC(=O)N2CCCCC2CN2CCCC2)cc1 InChI=1S/C19H25F3N2O/c20-19(21,22)16-8-6-15(7-9-16)13-18(25)24-12-2-1-5-17(24)14-23-10-3-4-11-23/h6-9,17H,1-5,10-14H2 RFTWMVGLYKJUCZ-UHFFFAOYSA-N 50008895 1-(2-Pyrrolidin-1-ylmethyl-piperidin-1-yl)-2-(4-trifluoromethyl-phenyl)-ethanone(HCl)::CHEMBL128542 Mu-type opioid receptor Cavia cutleri 2340 ChEMBL 10.1021/jm00105a061 10.7270/Q23777N1 1846921 Vecchietti, V; Giordani, A; Giardina, G; Colle, R; Clarke, GD Zambeletti Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008895 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008895&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14810960 103921996 CHEMBL128542 ZINC00596666 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50002342 CSCC[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(N)=O InChI=1S/C44H62N10O10S2/c1-25(2)18-34(42(62)50-32(15-17-66-4)40(60)51-33(38(46)58)22-37(56)57)52-44(64)36(21-28-23-47-24-48-28)54-43(63)35(20-26-8-6-5-7-9-26)53-41(61)31(14-16-65-3)49-39(59)30(45)19-27-10-12-29(55)13-11-27/h5-13,23-25,30-36,55H,14-22,45H2,1-4H3,(H2,46,58)(H,47,48)(H,49,59)(H,50,62)(H,51,60)(H,52,64)(H,53,61)(H,54,63)(H,56,57)/t30-,31+,32-,33-,34-,35-,36-/m0/s1 BHSURCCZOBVHJJ-NWOHMYAQSA-N 50000518 3-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyrylamino}-3-phenyl-propionylamino)-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-4-methylsulfanyl-butyrylamino)-succinamic acid::3-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyrylamino}-3-phenyl-propionylamino)-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-4-methylsulfanyl-butyrylamino)-succinamic acid (deltorphin A)::CHEMBL20775 Mu-type opioid receptor Cavia cutleri 4420 ChEMBL 10.1021/jm00099a025 10.7270/Q2H70DRH 1331451 Schiller, PW; Weltrowska, G; Nguyen, TM; Wilkes, BC; Chung, NN; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000518&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3035060 103915066 CHEMBL20775 C18010 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50057583 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)C1(CCc2ccccc2C1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C39H54N8O10/c1-20(2)31(36(55)42-19-29(41)49)46-37(56)32(21(3)4)45-35(54)28(17-30(50)51)44-38(57)39(15-14-24-8-6-7-9-25(24)18-39)47-33(52)22(5)43-34(53)27(40)16-23-10-12-26(48)13-11-23/h6-13,20-22,27-28,31-32,48H,14-19,40H2,1-5H3,(H2,41,49)(H,42,55)(H,43,53)(H,44,57)(H,45,54)(H,46,56)(H,47,52)(H,50,51)/t22-,27+,28+,31+,32+,39?/m1/s1 WCJNWJPRBIKFOI-RKPARCAKSA-N 50001459 3-[(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-1,2,3,4-tetrahydro-naphthalene-2-carbonyl)-amino]-N-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid::CHEMBL124941::H-Tyr-D-Ala-(R or S)Atc-Asp-Val-Val-Gly-NH2 Mu-type opioid receptor Cavia cutleri 1820 ChEMBL 10.1021/jm00099a025 10.7270/Q2H70DRH 1331451 Schiller, PW; Weltrowska, G; Nguyen, TM; Wilkes, BC; Chung, NN; Lemieux, C Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001459&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44348645 103915924 CHEMBL124941 ZINC95548274 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50059093 CC(C)(C)c1ccc(C[C@@H]2NC(=O)[C@H](CSSC(C)(C)[C@H](NC2=O)C(O)=O)NC(=O)[C@@H](N)Cc2ccc(O)cc2)cc1 InChI=1S/C30H40N4O6S2/c1-29(2,3)19-10-6-18(7-11-19)15-22-26(37)34-24(28(39)40)30(4,5)42-41-16-23(27(38)32-22)33-25(36)21(31)14-17-8-12-20(35)13-9-17/h6-13,21-24,35H,14-16,31H2,1-5H3,(H,32,38)(H,33,36)(H,34,37)(H,39,40)/t21-,22-,23-,24+/m0/s1 GZVHKYLTFQBPMK-NEWJYFPISA-N 50000654 10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-(4-tert-butyl-benzyl)-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL290968 Mu-type opioid receptor Cavia cutleri 10000 ChEMBL 10.1021/jm00087a006 10.7270/Q23T9HVN 1315870 Heyl, DL; Mosberg, HI University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000654 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000654&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15659194 103915202 CHEMBL290968 ZINC29326659 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50059174 CC1(C)SSC[C@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2cccc(O)c2)C(=O)N[C@@H]1C(O)=O InChI=1S/C26H32N4O7S2/c1-26(2)21(25(36)37)30-23(34)19(12-15-4-3-5-17(32)10-15)28-24(35)20(13-38-39-26)29-22(33)18(27)11-14-6-8-16(31)9-7-14/h3-10,18-21,31-32H,11-13,27H2,1-2H3,(H,28,35)(H,29,33)(H,30,34)(H,36,37)/t18-,19-,20-,21+/m0/s1 QRZQJIHCHBMRCN-XSDIEEQYSA-N 50000651 10-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7-(3-hydroxy-benzyl)-3,3-dimethyl-6,9-dioxo-1,2-dithia-5,8-diaza-cycloundecane-4-carboxylic acid::CHEMBL39647 Mu-type opioid receptor Cavia cutleri 712 ChEMBL 10.1021/jm00087a006 10.7270/Q23T9HVN 1315870 Heyl, DL; Mosberg, HI University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000651 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000651&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 15659196 103915199 CHEMBL39647 ZINC29324996 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50663648 CCC[C@@](C)(O)[C@H]1C[C@]23C=C[C@]1(OC)[C@@H]1Oc4c5c(C[C@H]2N(C)CC[C@@]315)ccc4O InChI=1S/C25H33NO4/c1-5-8-22(2,28)17-14-23-9-10-25(17,29-4)21-24(23)11-12-26(3)18(23)13-15-6-7-16(27)20(30-21)19(15)24/h6-7,9-10,17-18,21,27-28H,5,8,11-14H2,1-4H3/t17-,18-,21-,22-,23-,24+,25-/m1/s1 CAHCBJPUTCKATP-FAWZKKEFSA-N 50123599 ETORPHINE Mu-type opioid receptor Cavia cutleri 0.480000 ChEMBL 10.1021/jm00102a012 10.7270/Q27S7PCK 1335078 Klein, P; Nelson, WL University of Washington http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123599 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123599&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 644209 321902021 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50663665 CN([C@H]1CC[C@@]2(CCCO2)C[C@@H]1N1CCCC1)C(=O)Cc1ccccc1 InChI=1S/C22H32N2O2/c1-23(21(25)16-18-8-3-2-4-9-18)19-10-12-22(11-7-15-26-22)17-20(19)24-13-5-6-14-24/h2-4,8-9,19-20H,5-7,10-17H2,1H3/t19-,20-,22-/m0/s1 PGZRDDYTKFZSFR-ONTIZHBOSA-N 21130 N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl)-1-oxaspiro[4.5]decan-8-yl]acetamide::N-methyl-N-(7-(1-pyrrolidinyl)-1-oxaspiro(4,5)dec-8-yl)benzeneacetamide::U-69593::U69,593::[3H]U69593 Mu-type opioid receptor Cavia cutleri 551 ChEMBL 10.1021/jm00102a019 10.7270/Q2416XPM 1361580 Choi, H; Murray, TF; DeLander, GE; Caldwell, V; Aldrich, JV Oregon State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21130&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 105104 49689203 73357 1655 ZINC02517042 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015543 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 7.7 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015548 CNC(Cc1ccc(O)cc1)C(=O)NCC(=O)NCC(=O)NC(Cc1ccc(cc1)[N+]([O-])=O)C(=O)NC(CC(C)C)C(=O)NC(CCC[N-]C(N)=[NH2+])C(=O)NC(CCC[N-]C(N)=[NH2+])C(=O)NC(CC(C)C)C(N)=O InChI=1S/C47H74N16O11/c1-26(2)20-34(40(48)67)61-43(70)33(9-7-19-55-47(51)52)59-42(69)32(8-6-18-54-46(49)50)60-44(71)36(21-27(3)4)62-45(72)37(23-28-10-14-30(15-11-28)63(73)74)58-39(66)25-56-38(65)24-57-41(68)35(53-5)22-29-12-16-31(64)17-13-29/h10-17,26-27,32-37,53H,6-9,18-25H2,1-5H3,(H18,48,49,50,51,52,54,55,56,57,58,59,60,61,62,64,65,66,67,68,69,70,71,72) RKKYQSUGOCWQRV-UHFFFAOYSA-N 50010542 2-[5-Guanidino-2-(5-guanidino-2-{2-[2-(2-{2-[3-(4-hydroxy-phenyl)-2-methylamino-propionylamino]-acetylamino}-acetylamino)-3-(4-nitro-phenyl)-propionylamino]-4-methyl-pentanoylamino}-pentanoylamino)-pentanoylamino]-4-methyl-pentanoic acid amide::CHEMBL410611 Mu-type opioid receptor Cavia cutleri 1.3 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010542 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010542&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 13935836 103923318 CHEMBL410611 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50015581 CCNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)N(C)C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC InChI=1S/C50H81N15O9/c1-8-56-44(70)37(24-30(2)3)64-47(73)40(17-13-23-58-50(53)54)65(7)48(74)35(16-12-22-57-49(51)52)62-45(71)38(25-31(4)5)63-46(72)39(27-32-14-10-9-11-15-32)61-42(68)29-59-41(67)28-60-43(69)36(55-6)26-33-18-20-34(66)21-19-33/h9-11,14-15,18-21,30-31,35-40,55,66H,8,12-13,16-17,22-29H2,1-7H3,(H,56,70)(H,59,67)(H,60,69)(H,61,68)(H,62,71)(H,63,72)(H,64,73)(H4,51,52,57)(H4,53,54,58)/t35-,36-,37-,38-,39+,40-/m0/s1 JENWDDCMEATQSR-NGXVWMITSA-N 50010534 2-[2-(2-{2-[3-(4-Hydroxy-phenyl)-2-methylamino-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid (1-{[1-(1-ethylcarbamoyl-3-methyl-butylcarbamoyl)-4-guanidino-butyl]-methyl-carbamoyl}-4-guanidino-butyl)-amide::CHEMBL412325 Mu-type opioid receptor Cavia cutleri 4.5 ChEMBL 10.1021/jm00163a034 10.7270/Q2QV3KG6 1967312 Yoshino, H; Nakazawa, T; Arakawa, Y; Kaneko, T; Tsuchiya, Y; Matsunaga, M; Araki, S; Ikeda, M; Yamatsu, K; Tachibana, S Eisai Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010534&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44306952 103923310 CHEMBL412325 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50703546 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)\C(C[C@@]35O)=C\c1ccccc1 InChI=1S/C27H27NO4/c29-20-9-8-18-13-21-27(31)14-19(12-16-4-2-1-3-5-16)23(30)25-26(27,22(18)24(20)32-25)10-11-28(21)15-17-6-7-17/h1-5,8-9,12,17,21,25,29,31H,6-7,10-11,13-15H2/b19-12+/t21-,25+,26+,27-/m1/s1 WXOUFNFMPVMGFZ-BDQAUFNLSA-N 50454798 7-Benzylidenenaltrexone::BNTX Mu-type opioid receptor Cavia cutleri 26 ChEMBL 10.1016/j.bmcl.2016.11.057 10.7270/Q22V2JBQ 28011222 Healy, JR; Bezawada, P; Griggs, NW; Devereaux, AL; Matsumoto, RR; Traynor, JR; Coop, A; Cunningham, CW West Virginia University School of Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50454798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50454798&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5310988 225146325 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50700544 C[N+]1(CC=C)CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)CCC4=O)ccc5O InChI=1S/C20H23NO4/c1-3-9-21(2)10-8-19-16-12-4-5-13(22)17(16)25-18(19)14(23)6-7-20(19,24)15(21)11-12/h3-5,15,18,24H,1,6-11H2,2H3/p+1/t15-,18+,19+,20-,21?/m1/s1 PCSQOABIHJXZMR-MGQKVWQSSA-O 83098 (4R,4aS,7aR,12bS)-3-allyl-4a,9-dihydroxy-3-methyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-3-ium-7-one;iodide::(4R,4aS,7aR,12bS)-3-methyl-4a,9-bis(oxidanyl)-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-3-ium-7-one;iodide::(4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-methyl-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-3-ium-7-one;iodide::MLS001334009::Naloxone methiodide::SMR000875254::cid_16219719 Mu-type opioid receptor Cavia cutleri 18 ChEMBL 10.1016/j.ejmech.2016.09.077 10.7270/Q2J38VTR 27721146 Prezzavento, O; Arena, E; Sánchez-Fernández, C; Turnaturi, R; Parenti, C; Marrazzo, A; Catalano, R; Amata, E; Pasquinucci, L; Cobos, EJ University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=83098 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=83098&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5486183 252658299 ZINC06068283 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50733154 COC(=O)N1CCN([C@@H]2[C@H](CCC[C@H]12)N1CC[C@H](O)C1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C22H29Cl2N3O4/c1-31-22(30)26-9-10-27(20(29)12-14-5-6-16(23)17(24)11-14)21-18(3-2-4-19(21)26)25-8-7-15(28)13-25/h5-6,11,15,18-19,21,28H,2-4,7-10,12-13H2,1H3/t15-,18-,19-,21+/m0/s1 BEWAPTMRQKYOSC-LDBRAYGESA-N 50236865 CHEMBL4095192 Mu-type opioid receptor Cavia cutleri 184 ChEMBL 10.1021/acs.jmedchem.6b01868 10.7270/Q20C4Z1Z 28218838 Soeberdt, M; Molenveld, P; Storcken, RP; Bouzanne des Mazery, R; Sterk, GJ; Autar, R; Bolster, MG; Wagner, C; Aerts, SN; van Holst, FR; Wegert, A; Tangherlini, G; Frehland, B; Schepmann, D; Metze, D; Lotts, T; Knie, U; Lin, KY; Huang, TY; Lai, CC; Ständer, S; Wünsch, B; Abels, C Dr. August Wolff GmbH & Co. KG Arzneimittel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50236865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50236865&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 137639933 385213520 CHEMBL4095192 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50733159 COC(=O)N1CCN([C@@H]2[C@H](CCC[C@H]12)N1CC[C@H](O)C1)C(=O)Cc1ccc(F)c(Cl)c1 InChI=1S/C22H29ClFN3O4/c1-31-22(30)26-9-10-27(20(29)12-14-5-6-17(24)16(23)11-14)21-18(3-2-4-19(21)26)25-8-7-15(28)13-25/h5-6,11,15,18-19,21,28H,2-4,7-10,12-13H2,1H3/t15-,18-,19-,21+/m0/s1 XYUJCLASLNMYPP-LDBRAYGESA-N 50236866 CHEMBL4061582 Mu-type opioid receptor Cavia cutleri 1300 ChEMBL 10.1021/acs.jmedchem.6b01868 10.7270/Q20C4Z1Z 28218838 Soeberdt, M; Molenveld, P; Storcken, RP; Bouzanne des Mazery, R; Sterk, GJ; Autar, R; Bolster, MG; Wagner, C; Aerts, SN; van Holst, FR; Wegert, A; Tangherlini, G; Frehland, B; Schepmann, D; Metze, D; Lotts, T; Knie, U; Lin, KY; Huang, TY; Lai, CC; Ständer, S; Wünsch, B; Abels, C Dr. August Wolff GmbH & Co. KG Arzneimittel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50236866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50236866&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 137638013 385213521 CHEMBL4061582 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50733169 COC(=O)N1CCN([C@@H]2[C@H](CCC[C@H]12)N1CC[C@H](O)C1)C(=O)Cc1ccc(Cl)c(F)c1 InChI=1S/C22H29ClFN3O4/c1-31-22(30)26-9-10-27(20(29)12-14-5-6-16(23)17(24)11-14)21-18(3-2-4-19(21)26)25-8-7-15(28)13-25/h5-6,11,15,18-19,21,28H,2-4,7-10,12-13H2,1H3/t15-,18-,19-,21+/m0/s1 MRVTXRYQPMUXJY-LDBRAYGESA-N 50236867 CHEMBL4083401 Mu-type opioid receptor Cavia cutleri 551 ChEMBL 10.1021/acs.jmedchem.6b01868 10.7270/Q20C4Z1Z 28218838 Soeberdt, M; Molenveld, P; Storcken, RP; Bouzanne des Mazery, R; Sterk, GJ; Autar, R; Bolster, MG; Wagner, C; Aerts, SN; van Holst, FR; Wegert, A; Tangherlini, G; Frehland, B; Schepmann, D; Metze, D; Lotts, T; Knie, U; Lin, KY; Huang, TY; Lai, CC; Ständer, S; Wünsch, B; Abels, C Dr. August Wolff GmbH & Co. KG Arzneimittel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50236867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50236867&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 137646062 385213522 CHEMBL4083401 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50733172 COC(=O)N1CCN([C@@H]2[C@H](CCC[C@H]12)N1CC[C@H](O)C1)C(=O)Cc1ccc(Cl)cc1 InChI=1S/C22H30ClN3O4/c1-30-22(29)25-11-12-26(20(28)13-15-5-7-16(23)8-6-15)21-18(3-2-4-19(21)25)24-10-9-17(27)14-24/h5-8,17-19,21,27H,2-4,9-14H2,1H3/t17-,18-,19-,21+/m0/s1 AJLSVHJDFCYZDY-VNYTWHDVSA-N 50236868 CHEMBL4091184 Mu-type opioid receptor Cavia cutleri 365 ChEMBL 10.1021/acs.jmedchem.6b01868 10.7270/Q20C4Z1Z 28218838 Soeberdt, M; Molenveld, P; Storcken, RP; Bouzanne des Mazery, R; Sterk, GJ; Autar, R; Bolster, MG; Wagner, C; Aerts, SN; van Holst, FR; Wegert, A; Tangherlini, G; Frehland, B; Schepmann, D; Metze, D; Lotts, T; Knie, U; Lin, KY; Huang, TY; Lai, CC; Ständer, S; Wünsch, B; Abels, C Dr. August Wolff GmbH & Co. KG Arzneimittel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50236868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50236868&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 137642394 385213523 CHEMBL4091184 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50733178 COC(=O)N1CCN([C@@H]2[C@H](CCC[C@H]12)N1CC[C@H](O)C1)C(=O)Cc1cccc(Cl)c1 InChI=1S/C22H30ClN3O4/c1-30-22(29)25-10-11-26(20(28)13-15-4-2-5-16(23)12-15)21-18(6-3-7-19(21)25)24-9-8-17(27)14-24/h2,4-5,12,17-19,21,27H,3,6-11,13-14H2,1H3/t17-,18-,19-,21+/m0/s1 AUUZIEHJJBQQIG-VNYTWHDVSA-N 50236869 CHEMBL4092100 Mu-type opioid receptor Cavia cutleri 512 ChEMBL 10.1021/acs.jmedchem.6b01868 10.7270/Q20C4Z1Z 28218838 Soeberdt, M; Molenveld, P; Storcken, RP; Bouzanne des Mazery, R; Sterk, GJ; Autar, R; Bolster, MG; Wagner, C; Aerts, SN; van Holst, FR; Wegert, A; Tangherlini, G; Frehland, B; Schepmann, D; Metze, D; Lotts, T; Knie, U; Lin, KY; Huang, TY; Lai, CC; Ständer, S; Wünsch, B; Abels, C Dr. August Wolff GmbH & Co. KG Arzneimittel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50236869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50236869&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 137653556 385213524 CHEMBL4092100 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50733179 COC(=O)N1CCN([C@@H]2[C@H](CCC[C@H]12)N1CC[C@H](O)C1)C(=O)Cc1ccc(c(Cl)c1)C(F)(F)F InChI=1S/C23H29ClF3N3O4/c1-34-22(33)29-9-10-30(20(32)12-14-5-6-16(17(24)11-14)23(25,26)27)21-18(3-2-4-19(21)29)28-8-7-15(31)13-28/h5-6,11,15,18-19,21,31H,2-4,7-10,12-13H2,1H3/t15-,18-,19-,21+/m0/s1 YHBAKZWRSAFSGD-LDBRAYGESA-N 50236870 CHEMBL4064380 Mu-type opioid receptor Cavia cutleri 612 ChEMBL 10.1021/acs.jmedchem.6b01868 10.7270/Q20C4Z1Z 28218838 Soeberdt, M; Molenveld, P; Storcken, RP; Bouzanne des Mazery, R; Sterk, GJ; Autar, R; Bolster, MG; Wagner, C; Aerts, SN; van Holst, FR; Wegert, A; Tangherlini, G; Frehland, B; Schepmann, D; Metze, D; Lotts, T; Knie, U; Lin, KY; Huang, TY; Lai, CC; Ständer, S; Wünsch, B; Abels, C Dr. August Wolff GmbH & Co. KG Arzneimittel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50236870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50236870&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 137637157 385213525 CHEMBL4064380 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50733180 Clc1ccc(CC(=O)N2CCN[C@H]3CCC[C@@H]([C@@H]23)N2CCCC2)cc1Cl InChI=1S/C20H27Cl2N3O/c21-15-7-6-14(12-16(15)22)13-19(26)25-11-8-23-17-4-3-5-18(20(17)25)24-9-1-2-10-24/h6-7,12,17-18,20,23H,1-5,8-11,13H2/t17-,18-,20-/m0/s1 LWDJYEJRZVMWMH-BJLQDIEVSA-N 50236871 CHEMBL4069231 Mu-type opioid receptor Cavia cutleri 217 ChEMBL 10.1021/acs.jmedchem.6b01868 10.7270/Q20C4Z1Z 28218838 Soeberdt, M; Molenveld, P; Storcken, RP; Bouzanne des Mazery, R; Sterk, GJ; Autar, R; Bolster, MG; Wagner, C; Aerts, SN; van Holst, FR; Wegert, A; Tangherlini, G; Frehland, B; Schepmann, D; Metze, D; Lotts, T; Knie, U; Lin, KY; Huang, TY; Lai, CC; Ständer, S; Wünsch, B; Abels, C Dr. August Wolff GmbH & Co. KG Arzneimittel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50236871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50236871&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 117697800 385213526 CHEMBL4069231 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50733181 COC(=O)CN1CCN([C@@H]2[C@H](CCC[C@H]12)N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C23H31Cl2N3O3/c1-31-22(30)15-27-11-12-28(21(29)14-16-7-8-17(24)18(25)13-16)23-19(5-4-6-20(23)27)26-9-2-3-10-26/h7-8,13,19-20,23H,2-6,9-12,14-15H2,1H3/t19-,20-,23+/m0/s1 MINYCOUUSMPSIG-SXWKCWPCSA-N 50236872 CHEMBL4072972 Mu-type opioid receptor Cavia cutleri 1230 ChEMBL 10.1021/acs.jmedchem.6b01868 10.7270/Q20C4Z1Z 28218838 Soeberdt, M; Molenveld, P; Storcken, RP; Bouzanne des Mazery, R; Sterk, GJ; Autar, R; Bolster, MG; Wagner, C; Aerts, SN; van Holst, FR; Wegert, A; Tangherlini, G; Frehland, B; Schepmann, D; Metze, D; Lotts, T; Knie, U; Lin, KY; Huang, TY; Lai, CC; Ständer, S; Wünsch, B; Abels, C Dr. August Wolff GmbH & Co. KG Arzneimittel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50236872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50236872&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 137632074 385213527 CHEMBL4072972 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50733379 CS(=O)(=O)N1CCN([C@@H]2[C@H](CCC[C@H]12)N1CC[C@H](O)C1)C(=O)Cc1ccc(Cl)c(F)c1 InChI=1S/C21H29ClFN3O4S/c1-31(29,30)26-10-9-25(20(28)12-14-5-6-16(22)17(23)11-14)21-18(3-2-4-19(21)26)24-8-7-15(27)13-24/h5-6,11,15,18-19,21,27H,2-4,7-10,12-13H2,1H3/t15-,18-,19-,21+/m0/s1 CRCNINUFPZHOIF-LDBRAYGESA-N 50236885 CHEMBL4088788 Mu-type opioid receptor Cavia cutleri 308 ChEMBL 10.1021/acs.jmedchem.6b01868 10.7270/Q20C4Z1Z 28218838 Soeberdt, M; Molenveld, P; Storcken, RP; Bouzanne des Mazery, R; Sterk, GJ; Autar, R; Bolster, MG; Wagner, C; Aerts, SN; van Holst, FR; Wegert, A; Tangherlini, G; Frehland, B; Schepmann, D; Metze, D; Lotts, T; Knie, U; Lin, KY; Huang, TY; Lai, CC; Ständer, S; Wünsch, B; Abels, C Dr. August Wolff GmbH & Co. KG Arzneimittel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50236885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50236885&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 137634296 385213540 CHEMBL4088788 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50733381 Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1 UZHSEJADLWPNLE-GRGSLBFTSA-N 54795 (4R,4aS,7aR,12bS)-3-allyl-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::(4R,4aS,7aR,12bS)-4a,9-bis(oxidanyl)-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::(4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::MLS000069540::NALOXONE HYDROCHLORIDE::SMR000058766::cid_5464092 Mu-type opioid receptor Cavia cutleri 2.3 ChEMBL 10.1021/acs.jmedchem.6b01868 10.7270/Q20C4Z1Z 28218838 Soeberdt, M; Molenveld, P; Storcken, RP; Bouzanne des Mazery, R; Sterk, GJ; Autar, R; Bolster, MG; Wagner, C; Aerts, SN; van Holst, FR; Wegert, A; Tangherlini, G; Frehland, B; Schepmann, D; Metze, D; Lotts, T; Knie, U; Lin, KY; Huang, TY; Lai, CC; Ständer, S; Wünsch, B; Abels, C Dr. August Wolff GmbH & Co. KG Arzneimittel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=54795 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=54795&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5284596 252634813 DB01183 C07252 ZINC01385891 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50733384 CCOC(=O)CN1CCN([C@@H]2[C@H](CCC[C@H]12)N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C24H33Cl2N3O3/c1-2-32-23(31)16-28-12-13-29(22(30)15-17-8-9-18(25)19(26)14-17)24-20(6-5-7-21(24)28)27-10-3-4-11-27/h8-9,14,20-21,24H,2-7,10-13,15-16H2,1H3/t20-,21-,24+/m0/s1 KDJMQBSGHNZTQN-AWRGLXIESA-N 50236886 CHEMBL4099849 Mu-type opioid receptor Cavia cutleri 830 ChEMBL 10.1021/acs.jmedchem.6b01868 10.7270/Q20C4Z1Z 28218838 Soeberdt, M; Molenveld, P; Storcken, RP; Bouzanne des Mazery, R; Sterk, GJ; Autar, R; Bolster, MG; Wagner, C; Aerts, SN; van Holst, FR; Wegert, A; Tangherlini, G; Frehland, B; Schepmann, D; Metze, D; Lotts, T; Knie, U; Lin, KY; Huang, TY; Lai, CC; Ständer, S; Wünsch, B; Abels, C Dr. August Wolff GmbH & Co. KG Arzneimittel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50236886 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50236886&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 137661659 385213541 CHEMBL4099849 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50733393 CS(=O)(=O)N1CCN([C@@H]2[C@H](CCC[C@H]12)N1CC[C@H](O)C1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C21H29Cl2N3O4S/c1-31(29,30)26-10-9-25(20(28)12-14-5-6-16(22)17(23)11-14)21-18(3-2-4-19(21)26)24-8-7-15(27)13-24/h5-6,11,15,18-19,21,27H,2-4,7-10,12-13H2,1H3/t15-,18-,19-,21+/m0/s1 AQDACVMGTUFZLP-LDBRAYGESA-N 50236875 CHEMBL4074031 Mu-type opioid receptor Cavia cutleri 336 ChEMBL 10.1021/acs.jmedchem.6b01868 10.7270/Q20C4Z1Z 28218838 Soeberdt, M; Molenveld, P; Storcken, RP; Bouzanne des Mazery, R; Sterk, GJ; Autar, R; Bolster, MG; Wagner, C; Aerts, SN; van Holst, FR; Wegert, A; Tangherlini, G; Frehland, B; Schepmann, D; Metze, D; Lotts, T; Knie, U; Lin, KY; Huang, TY; Lai, CC; Ständer, S; Wünsch, B; Abels, C Dr. August Wolff GmbH & Co. KG Arzneimittel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50236875 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50236875&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 137640628 385213530 CHEMBL4074031 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50733394 COC(=O)N1CCN([C@@H]2[C@H](CCC[C@H]12)N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C22H29Cl2N3O3/c1-30-22(29)26-11-12-27(20(28)14-15-7-8-16(23)17(24)13-15)21-18(5-4-6-19(21)26)25-9-2-3-10-25/h7-8,13,18-19,21H,2-6,9-12,14H2,1H3/t18-,19-,21+/m0/s1 PAVYSOUZQLFNIW-IRFCIJBXSA-N 50130757 CHEMBL3634516 Mu-type opioid receptor Cavia cutleri 43 ChEMBL 10.1021/acs.jmedchem.6b01868 10.7270/Q20C4Z1Z 28218838 Soeberdt, M; Molenveld, P; Storcken, RP; Bouzanne des Mazery, R; Sterk, GJ; Autar, R; Bolster, MG; Wagner, C; Aerts, SN; van Holst, FR; Wegert, A; Tangherlini, G; Frehland, B; Schepmann, D; Metze, D; Lotts, T; Knie, U; Lin, KY; Huang, TY; Lai, CC; Ständer, S; Wünsch, B; Abels, C Dr. August Wolff GmbH & Co. KG Arzneimittel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130757 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130757&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 86280667 321903189 CHEMBL3634516 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50733400 CS(=O)(=O)N1CCN([C@@H]2[C@H](CCC[C@H]12)N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C21H29Cl2N3O3S/c1-30(28,29)26-12-11-25(20(27)14-15-7-8-16(22)17(23)13-15)21-18(5-4-6-19(21)26)24-9-2-3-10-24/h7-8,13,18-19,21H,2-6,9-12,14H2,1H3/t18-,19-,21+/m0/s1 FTGMNZSEIMJTJA-IRFCIJBXSA-N 50236878 CHEMBL4084350 Mu-type opioid receptor Cavia cutleri 91 ChEMBL 10.1021/acs.jmedchem.6b01868 10.7270/Q20C4Z1Z 28218838 Soeberdt, M; Molenveld, P; Storcken, RP; Bouzanne des Mazery, R; Sterk, GJ; Autar, R; Bolster, MG; Wagner, C; Aerts, SN; van Holst, FR; Wegert, A; Tangherlini, G; Frehland, B; Schepmann, D; Metze, D; Lotts, T; Knie, U; Lin, KY; Huang, TY; Lai, CC; Ständer, S; Wünsch, B; Abels, C Dr. August Wolff GmbH & Co. KG Arzneimittel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50236878 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50236878&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 137647271 385213533 CHEMBL4084350 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50733401 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 5.2 ChEMBL 10.1021/acs.jmedchem.6b01868 10.7270/Q20C4Z1Z 28218838 Soeberdt, M; Molenveld, P; Storcken, RP; Bouzanne des Mazery, R; Sterk, GJ; Autar, R; Bolster, MG; Wagner, C; Aerts, SN; van Holst, FR; Wegert, A; Tangherlini, G; Frehland, B; Schepmann, D; Metze, D; Lotts, T; Knie, U; Lin, KY; Huang, TY; Lai, CC; Ständer, S; Wünsch, B; Abels, C Dr. August Wolff GmbH & Co. KG Arzneimittel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50733418 CN(C)S(=O)(=O)N1CCN([C@@H]2[C@H](CCC[C@H]12)N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C22H32Cl2N4O3S/c1-25(2)32(30,31)28-13-12-27(21(29)15-16-8-9-17(23)18(24)14-16)22-19(6-5-7-20(22)28)26-10-3-4-11-26/h8-9,14,19-20,22H,3-7,10-13,15H2,1-2H3/t19-,20-,22+/m0/s1 GJVWJKZFYRYESJ-JAXLGGSGSA-N 50236881 CHEMBL4094571 Mu-type opioid receptor Cavia cutleri 21 ChEMBL 10.1021/acs.jmedchem.6b01868 10.7270/Q20C4Z1Z 28218838 Soeberdt, M; Molenveld, P; Storcken, RP; Bouzanne des Mazery, R; Sterk, GJ; Autar, R; Bolster, MG; Wagner, C; Aerts, SN; van Holst, FR; Wegert, A; Tangherlini, G; Frehland, B; Schepmann, D; Metze, D; Lotts, T; Knie, U; Lin, KY; Huang, TY; Lai, CC; Ständer, S; Wünsch, B; Abels, C Dr. August Wolff GmbH & Co. KG Arzneimittel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50236881 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50236881&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 137640513 385213536 CHEMBL4094571 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50748309 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1 DQCKKXVULJGBQN-XFWGSAIBSA-N 60212 (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride::MLS000069607::NALTREXONE HYDROCHLORIDE::SMR000058767::US10988481, Compound NTX::US9107954, naltrexone::cid_5485201 Mu-type opioid receptor Cavia cutleri 0.260000 ChEMBL 10.1016/j.bmcl.2016.06.067 10.7270/Q298894Q 28291693 Li, G; Low, PS Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60212&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5360515 252639834 DB00704 C07253 ZINC00001773 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50953430 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cccc(C=C)c1)C(=O)NCC(N)=O InChI=1S/C30H42N8O5/c1-4-19-7-5-8-20(13-19)14-25(28(42)36-16-26(32)40)38-29(43)24(9-6-10-35-30(33)34)37-27(41)23(31)15-22-17(2)11-21(39)12-18(22)3/h4-5,7-8,11-13,23-25,39H,1,6,9-10,14-16,31H2,2-3H3,(H2,32,40)(H,36,42)(H,37,41)(H,38,43)(H4,33,34,35)/t23-,24+,25-/m0/s1 AEUNEVRUSYOPSO-GVAUOCQISA-N 50274693 CHEMBL4126249 Mu-type opioid receptor Cavia cutleri 1.4 ChEMBL 10.1016/j.bmcl.2018.05.015 10.7270/Q2KW5JJJ 29853330 Willemse, T; Eiselt, E; Hollanders, K; Schepens, W; van Vlijmen, HWT; Chung, NN; Blais, V; Holleran, B; Longpré, JM; Schiller, PW; Maes, BUW; Sarret, P; Gendron, L; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274693&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145962739 405256992 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50953431 C[C@@H](NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](Cc1ccccc1C=C)C(=O)NCC(N)=O InChI=1S/C27H35N5O5/c1-5-18-8-6-7-9-19(18)12-23(27(37)30-14-24(29)34)32-25(35)17(4)31-26(36)22(28)13-21-15(2)10-20(33)11-16(21)3/h5-11,17,22-23,33H,1,12-14,28H2,2-4H3,(H2,29,34)(H,30,37)(H,31,36)(H,32,35)/t17-,22+,23+/m1/s1 KMLNSQRMFQZLGN-VSDWSMLSSA-N 50274694 CHEMBL4129901 Mu-type opioid receptor Cavia cutleri 1.2 ChEMBL 10.1016/j.bmcl.2018.05.015 10.7270/Q2KW5JJJ 29853330 Willemse, T; Eiselt, E; Hollanders, K; Schepens, W; van Vlijmen, HWT; Chung, NN; Blais, V; Holleran, B; Longpré, JM; Schiller, PW; Maes, BUW; Sarret, P; Gendron, L; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274694 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274694&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145963297 405256993 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50953445 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(C=C)cc1)C(=O)NCC(N)=O InChI=1S/C30H42N8O5/c1-4-19-7-9-20(10-8-19)14-25(28(42)36-16-26(32)40)38-29(43)24(6-5-11-35-30(33)34)37-27(41)23(31)15-22-17(2)12-21(39)13-18(22)3/h4,7-10,12-13,23-25,39H,1,5-6,11,14-16,31H2,2-3H3,(H2,32,40)(H,36,42)(H,37,41)(H,38,43)(H4,33,34,35)/t23-,24+,25-/m0/s1 YMVMXEIOULJWCY-GVAUOCQISA-N 50274687 CHEMBL4129548 Mu-type opioid receptor Cavia cutleri 24 ChEMBL 10.1016/j.bmcl.2018.05.015 10.7270/Q2KW5JJJ 29853330 Willemse, T; Eiselt, E; Hollanders, K; Schepens, W; van Vlijmen, HWT; Chung, NN; Blais, V; Holleran, B; Longpré, JM; Schiller, PW; Maes, BUW; Sarret, P; Gendron, L; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274687 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274687&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145963694 405256989 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50953446 C[C@@H](NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(O)=O InChI=1S/C25H32N4O6/c1-14-9-18(30)10-15(2)19(14)12-20(26)24(34)28-16(3)23(33)29-21(25(35)27-13-22(31)32)11-17-7-5-4-6-8-17/h4-10,16,20-21,30H,11-13,26H2,1-3H3,(H,27,35)(H,28,34)(H,29,33)(H,31,32)/t16-,20+,21+/m1/s1 CHOLZAWAZWSJAN-CZAAIQMYSA-N 50274689 CHEMBL4126050 Mu-type opioid receptor Cavia cutleri 1.5 ChEMBL 10.1016/j.bmcl.2018.05.015 10.7270/Q2KW5JJJ 29853330 Willemse, T; Eiselt, E; Hollanders, K; Schepens, W; van Vlijmen, HWT; Chung, NN; Blais, V; Holleran, B; Longpré, JM; Schiller, PW; Maes, BUW; Sarret, P; Gendron, L; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274689 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274689&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145953986 405256991 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50953453 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cccc(c1)-c1ccccc1)C(=O)NCC(N)=O InChI=1S/C34H44N8O5/c1-20-14-25(43)15-21(2)26(20)18-27(35)31(45)41-28(12-7-13-39-34(37)38)33(47)42-29(32(46)40-19-30(36)44)17-22-8-6-11-24(16-22)23-9-4-3-5-10-23/h3-6,8-11,14-16,27-29,43H,7,12-13,17-19,35H2,1-2H3,(H2,36,44)(H,40,46)(H,41,45)(H,42,47)(H4,37,38,39)/t27-,28+,29-/m0/s1 ZEAVNFWJYMLTDA-NHKHRBQYSA-N 50274710 CHEMBL4127226 Mu-type opioid receptor Cavia cutleri 62 ChEMBL 10.1016/j.bmcl.2018.05.015 10.7270/Q2KW5JJJ 29853330 Willemse, T; Eiselt, E; Hollanders, K; Schepens, W; van Vlijmen, HWT; Chung, NN; Blais, V; Holleran, B; Longpré, JM; Schiller, PW; Maes, BUW; Sarret, P; Gendron, L; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274710 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274710&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145962780 104118397 ZINC03987622 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50953454 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1-c1ccccc1)C(=O)NCC(N)=O InChI=1S/C34H44N8O5/c1-20-15-24(43)16-21(2)26(20)18-27(35)31(45)41-28(13-8-14-39-34(37)38)33(47)42-29(32(46)40-19-30(36)44)17-23-11-6-7-12-25(23)22-9-4-3-5-10-22/h3-7,9-12,15-16,27-29,43H,8,13-14,17-19,35H2,1-2H3,(H2,36,44)(H,40,46)(H,41,45)(H,42,47)(H4,37,38,39)/t27-,28+,29-/m0/s1 KCJRXZKWDKTEFK-NHKHRBQYSA-N 50274733 CHEMBL4127080 Mu-type opioid receptor Cavia cutleri 3.5 ChEMBL 10.1016/j.bmcl.2018.05.015 10.7270/Q2KW5JJJ 29853330 Willemse, T; Eiselt, E; Hollanders, K; Schepens, W; van Vlijmen, HWT; Chung, NN; Blais, V; Holleran, B; Longpré, JM; Schiller, PW; Maes, BUW; Sarret, P; Gendron, L; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274733 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274733&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145960634 405257001 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50953455 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cccc(c1)-c1ccsc1)C(=O)NCC(N)=O InChI=1S/C32H42N8O5S/c1-18-11-23(41)12-19(2)24(18)15-25(33)29(43)39-26(7-4-9-37-32(35)36)31(45)40-27(30(44)38-16-28(34)42)14-20-5-3-6-21(13-20)22-8-10-46-17-22/h3,5-6,8,10-13,17,25-27,41H,4,7,9,14-16,33H2,1-2H3,(H2,34,42)(H,38,44)(H,39,43)(H,40,45)(H4,35,36,37)/t25-,26+,27-/m0/s1 WTHOGRCQTCKRIC-VJGNERBWSA-N 50274738 CHEMBL4128313 Mu-type opioid receptor Cavia cutleri 30 ChEMBL 10.1016/j.bmcl.2018.05.015 10.7270/Q2KW5JJJ 29853330 Willemse, T; Eiselt, E; Hollanders, K; Schepens, W; van Vlijmen, HWT; Chung, NN; Blais, V; Holleran, B; Longpré, JM; Schiller, PW; Maes, BUW; Sarret, P; Gendron, L; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274738 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274738&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145962819 405257002 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50953456 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1C=C)C(=O)NCC(N)=O InChI=1S/C30H42N8O5/c1-4-19-8-5-6-9-20(19)14-25(28(42)36-16-26(32)40)38-29(43)24(10-7-11-35-30(33)34)37-27(41)23(31)15-22-17(2)12-21(39)13-18(22)3/h4-6,8-9,12-13,23-25,39H,1,7,10-11,14-16,31H2,2-3H3,(H2,32,40)(H,36,42)(H,37,41)(H,38,43)(H4,33,34,35)/t23-,24+,25-/m0/s1 VLZWBYWNWNPNJR-GVAUOCQISA-N 50274696 CHEMBL4126102 Mu-type opioid receptor Cavia cutleri 0.389000 ChEMBL 10.1016/j.bmcl.2018.05.015 10.7270/Q2KW5JJJ 29853330 Willemse, T; Eiselt, E; Hollanders, K; Schepens, W; van Vlijmen, HWT; Chung, NN; Blais, V; Holleran, B; Longpré, JM; Schiller, PW; Maes, BUW; Sarret, P; Gendron, L; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274696 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274696&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145961883 405256995 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50953457 COc1ccc(C[C@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C(=O)NCC(N)=O)cc1 InChI=1S/C29H42N8O6/c1-16-11-19(38)12-17(2)21(16)14-22(30)26(40)36-23(5-4-10-34-29(32)33)28(42)37-24(27(41)35-15-25(31)39)13-18-6-8-20(43-3)9-7-18/h6-9,11-12,22-24,38H,4-5,10,13-15,30H2,1-3H3,(H2,31,39)(H,35,41)(H,36,40)(H,37,42)(H4,32,33,34)/t22-,23+,24-/m0/s1 UAJIBHYIOKBSNN-VXNXHJTFSA-N 50274739 CHEMBL4127485 Mu-type opioid receptor Cavia cutleri 0.901000 ChEMBL 10.1016/j.bmcl.2018.05.015 10.7270/Q2KW5JJJ 29853330 Willemse, T; Eiselt, E; Hollanders, K; Schepens, W; van Vlijmen, HWT; Chung, NN; Blais, V; Holleran, B; Longpré, JM; Schiller, PW; Maes, BUW; Sarret, P; Gendron, L; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274739 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274739&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145962370 405257003 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50953458 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(F)cc1)C(=O)NCC(N)=O InChI=1S/C28H39FN8O5/c1-15-10-19(38)11-16(2)20(15)13-21(30)25(40)36-22(4-3-9-34-28(32)33)27(42)37-23(26(41)35-14-24(31)39)12-17-5-7-18(29)8-6-17/h5-8,10-11,21-23,38H,3-4,9,12-14,30H2,1-2H3,(H2,31,39)(H,35,41)(H,36,40)(H,37,42)(H4,32,33,34)/t21-,22+,23-/m0/s1 FTVVUDOEAAUYRK-ZRBLBEILSA-N 50274732 CHEMBL4127547 Mu-type opioid receptor Cavia cutleri 0.801000 ChEMBL 10.1016/j.bmcl.2018.05.015 10.7270/Q2KW5JJJ 29853330 Willemse, T; Eiselt, E; Hollanders, K; Schepens, W; van Vlijmen, HWT; Chung, NN; Blais, V; Holleran, B; Longpré, JM; Schiller, PW; Maes, BUW; Sarret, P; Gendron, L; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274732 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274732&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145961275 405257000 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50953459 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(Cl)cc1)C(=O)NCC(N)=O InChI=1S/C28H39ClN8O5/c1-15-10-19(38)11-16(2)20(15)13-21(30)25(40)36-22(4-3-9-34-28(32)33)27(42)37-23(26(41)35-14-24(31)39)12-17-5-7-18(29)8-6-17/h5-8,10-11,21-23,38H,3-4,9,12-14,30H2,1-2H3,(H2,31,39)(H,35,41)(H,36,40)(H,37,42)(H4,32,33,34)/t21-,22+,23-/m0/s1 ILPSPIMQHZJXNK-ZRBLBEILSA-N 50274695 CHEMBL4127702 Mu-type opioid receptor Cavia cutleri 2.4 ChEMBL 10.1016/j.bmcl.2018.05.015 10.7270/Q2KW5JJJ 29853330 Willemse, T; Eiselt, E; Hollanders, K; Schepens, W; van Vlijmen, HWT; Chung, NN; Blais, V; Holleran, B; Longpré, JM; Schiller, PW; Maes, BUW; Sarret, P; Gendron, L; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274695 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274695&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145963412 405256994 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50953460 CC(C)=Cc1ccccc1C[C@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)NCC(N)=O InChI=1S/C32H46N8O5/c1-18(2)12-21-8-5-6-9-22(21)15-27(30(44)38-17-28(34)42)40-31(45)26(10-7-11-37-32(35)36)39-29(43)25(33)16-24-19(3)13-23(41)14-20(24)4/h5-6,8-9,12-14,25-27,41H,7,10-11,15-17,33H2,1-4H3,(H2,34,42)(H,38,44)(H,39,43)(H,40,45)(H4,35,36,37)/t25-,26+,27-/m0/s1 ZDEUARDYFAZNOI-VJGNERBWSA-N 50274731 CHEMBL4126322 Mu-type opioid receptor Cavia cutleri 0.701000 ChEMBL 10.1016/j.bmcl.2018.05.015 10.7270/Q2KW5JJJ 29853330 Willemse, T; Eiselt, E; Hollanders, K; Schepens, W; van Vlijmen, HWT; Chung, NN; Blais, V; Holleran, B; Longpré, JM; Schiller, PW; Maes, BUW; Sarret, P; Gendron, L; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274731 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274731&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145961895 405256999 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50953461 C[C@@H](NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](Cc1ccccc1-c1ccsc1)C(=O)NCC(N)=O InChI=1S/C29H35N5O5S/c1-16-10-21(35)11-17(2)23(16)13-24(30)28(38)33-18(3)27(37)34-25(29(39)32-14-26(31)36)12-19-6-4-5-7-22(19)20-8-9-40-15-20/h4-11,15,18,24-25,35H,12-14,30H2,1-3H3,(H2,31,36)(H,32,39)(H,33,38)(H,34,37)/t18-,24+,25+/m1/s1 KBQHEKQLAFATQQ-YWWLGCSWSA-N 50274688 CHEMBL4129753 Mu-type opioid receptor Cavia cutleri 1.3 ChEMBL 10.1016/j.bmcl.2018.05.015 10.7270/Q2KW5JJJ 29853330 Willemse, T; Eiselt, E; Hollanders, K; Schepens, W; van Vlijmen, HWT; Chung, NN; Blais, V; Holleran, B; Longpré, JM; Schiller, PW; Maes, BUW; Sarret, P; Gendron, L; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274688 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274688&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145960967 405256990 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50953462 C[C@@H](NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N(C)[C@@H](Cc1ccccc1C=C)C(=O)NCC(N)=O InChI=1S/C28H37N5O5/c1-6-19-9-7-8-10-20(19)13-24(27(37)31-15-25(30)35)33(5)28(38)18(4)32-26(36)23(29)14-22-16(2)11-21(34)12-17(22)3/h6-12,18,23-24,34H,1,13-15,29H2,2-5H3,(H2,30,35)(H,31,37)(H,32,36)/t18-,23+,24+/m1/s1 QMSFTMNSMKWZSC-DKLXNKCPSA-N 50274679 CHEMBL4128530 Mu-type opioid receptor Cavia cutleri 0.641000 ChEMBL 10.1016/j.bmcl.2018.05.015 10.7270/Q2KW5JJJ 29853330 Willemse, T; Eiselt, E; Hollanders, K; Schepens, W; van Vlijmen, HWT; Chung, NN; Blais, V; Holleran, B; Longpré, JM; Schiller, PW; Maes, BUW; Sarret, P; Gendron, L; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274679 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274679&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145963053 405256987 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50953463 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(O)=O InChI=1S/C28H39N7O6/c1-16-11-19(36)12-17(2)20(16)14-21(29)25(39)34-22(9-6-10-32-28(30)31)27(41)35-23(26(40)33-15-24(37)38)13-18-7-4-3-5-8-18/h3-5,7-8,11-12,21-23,36H,6,9-10,13-15,29H2,1-2H3,(H,33,40)(H,34,39)(H,35,41)(H,37,38)(H4,30,31,32)/t21-,22+,23-/m0/s1 TUHRBBXHPLITAF-ZRBLBEILSA-N 50274686 CHEMBL4129679 Mu-type opioid receptor Cavia cutleri 2.3 ChEMBL 10.1016/j.bmcl.2018.05.015 10.7270/Q2KW5JJJ 29853330 Willemse, T; Eiselt, E; Hollanders, K; Schepens, W; van Vlijmen, HWT; Chung, NN; Blais, V; Holleran, B; Longpré, JM; Schiller, PW; Maes, BUW; Sarret, P; Gendron, L; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274686&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145961376 405256988 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50953464 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(O)=O InChI=1S/C38H53N7O11/c1-20(2)31(37(55)40-19-30(49)50)45-38(56)32(21(3)4)44-35(53)27(15-16-29(47)48)42-36(54)28(18-23-9-7-6-8-10-23)43-33(51)22(5)41-34(52)26(39)17-24-11-13-25(46)14-12-24/h6-14,20-22,26-28,31-32,46H,15-19,39H2,1-5H3,(H,40,55)(H,41,52)(H,42,54)(H,43,51)(H,44,53)(H,45,56)(H,47,48)(H,49,50)/t22-,26+,27+,28+,31+,32+/m1/s1 FWGXLJYMZWCJJV-RCEFDBTISA-N 50009146 (S)-4-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-4-{(S)-1-[(S)-1-(carboxymethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propylcarbamoyl}-butyric acid::4-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-4-{1-[1-(carboxymethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propylcarbamoyl}-butyric acid::CHEMBL26575 Mu-type opioid receptor Cavia cutleri 854 ChEMBL 10.1016/j.bmcl.2018.05.015 10.7270/Q2KW5JJJ 29853330 Willemse, T; Eiselt, E; Hollanders, K; Schepens, W; van Vlijmen, HWT; Chung, NN; Blais, V; Holleran, B; Longpré, JM; Schiller, PW; Maes, BUW; Sarret, P; Gendron, L; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009146 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009146&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9875568 103922203 CHEMBL26575 ZINC95608617 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50953512 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1-c1ccsc1)C(=O)NCC(N)=O InChI=1S/C32H42N8O5S/c1-18-12-22(41)13-19(2)24(18)15-25(33)29(43)39-26(8-5-10-37-32(35)36)31(45)40-27(30(44)38-16-28(34)42)14-20-6-3-4-7-23(20)21-9-11-46-17-21/h3-4,6-7,9,11-13,17,25-27,41H,5,8,10,14-16,33H2,1-2H3,(H2,34,42)(H,38,44)(H,39,43)(H,40,45)(H4,35,36,37)/t25-,26+,27-/m0/s1 LNSIZMKHCJCLED-VJGNERBWSA-N 50274697 CHEMBL4129689 Mu-type opioid receptor Cavia cutleri 1.5 ChEMBL 10.1016/j.bmcl.2018.05.015 10.7270/Q2KW5JJJ 29853330 Willemse, T; Eiselt, E; Hollanders, K; Schepens, W; van Vlijmen, HWT; Chung, NN; Blais, V; Holleran, B; Longpré, JM; Schiller, PW; Maes, BUW; Sarret, P; Gendron, L; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274697 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274697&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145961816 405256996 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50953513 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(cc1)C(F)(F)F)C(=O)NCC(N)=O InChI=1S/C29H39F3N8O5/c1-15-10-19(41)11-16(2)20(15)13-21(33)25(43)39-22(4-3-9-37-28(35)36)27(45)40-23(26(44)38-14-24(34)42)12-17-5-7-18(8-6-17)29(30,31)32/h5-8,10-11,21-23,41H,3-4,9,12-14,33H2,1-2H3,(H2,34,42)(H,38,44)(H,39,43)(H,40,45)(H4,35,36,37)/t21-,22+,23-/m0/s1 CZDZZPIQDHMNJS-ZRBLBEILSA-N 50274729 CHEMBL4128945 Mu-type opioid receptor Cavia cutleri 1.3 ChEMBL 10.1016/j.bmcl.2018.05.015 10.7270/Q2KW5JJJ 29853330 Willemse, T; Eiselt, E; Hollanders, K; Schepens, W; van Vlijmen, HWT; Chung, NN; Blais, V; Holleran, B; Longpré, JM; Schiller, PW; Maes, BUW; Sarret, P; Gendron, L; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274729 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274729&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145961135 405256997 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50953514 C[C@@H](NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](Cc1ccccc1-c1ccccc1)C(=O)NCC(N)=O InChI=1S/C31H37N5O5/c1-18-13-23(37)14-19(2)25(18)16-26(32)30(40)35-20(3)29(39)36-27(31(41)34-17-28(33)38)15-22-11-7-8-12-24(22)21-9-5-4-6-10-21/h4-14,20,26-27,37H,15-17,32H2,1-3H3,(H2,33,38)(H,34,41)(H,35,40)(H,36,39)/t20-,26+,27+/m1/s1 QFBGVCWOFLNHNT-PHXCCWLDSA-N 50274741 CHEMBL4126470 Mu-type opioid receptor Cavia cutleri 1.6 ChEMBL 10.1016/j.bmcl.2018.05.015 10.7270/Q2KW5JJJ 29853330 Willemse, T; Eiselt, E; Hollanders, K; Schepens, W; van Vlijmen, HWT; Chung, NN; Blais, V; Holleran, B; Longpré, JM; Schiller, PW; Maes, BUW; Sarret, P; Gendron, L; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274741 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274741&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145961040 405257005 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50953515 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C)[C@@H](Cc1ccccc1)C(=O)NCCO InChI=1S/C26H35N5O6/c1-17(30-25(36)21(27)14-19-8-10-20(33)11-9-19)24(35)29-16-23(34)31(2)22(26(37)28-12-13-32)15-18-6-4-3-5-7-18/h3-11,17,21-22,32-33H,12-16,27H2,1-2H3,(H,28,37)(H,29,35)(H,30,36)/t17-,21+,22+/m1/s1 HPZJMUBDEAMBFI-WTNAPCKOSA-N 21015 (2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]-N-methylacetamido}-N-(2-hydroxyethyl)-3-phenylpropanamide::2-Ala-4-MePhe-5-Gly-Enkephalin::CHEMBL38874::D-Ala2-MePhe4-Met(0)5-enkephalin-ol::DAMGO::RX 783006::US11492374, ID 2::[3H]DAMGO::[tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephalin Mu-type opioid receptor Cavia cutleri 28 ChEMBL 10.1016/j.bmcl.2018.05.015 10.7270/Q2KW5JJJ 29853330 Willemse, T; Eiselt, E; Hollanders, K; Schepens, W; van Vlijmen, HWT; Chung, NN; Blais, V; Holleran, B; Longpré, JM; Schiller, PW; Maes, BUW; Sarret, P; Gendron, L; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21015&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5462471 49689088 CHEMBL38874 1647 C04080 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50988268 C[C@@H](NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@H]1Cc2c(CN(CC(N)=O)C1=O)ccc1ccccc21 InChI=1S/C30H35N5O5/c1-16-10-21(36)11-17(2)23(16)12-25(31)29(39)33-18(3)28(38)34-26-13-24-20(14-35(30(26)40)15-27(32)37)9-8-19-6-4-5-7-22(19)24/h4-11,18,25-26,36H,12-15,31H2,1-3H3,(H2,32,37)(H,33,39)(H,34,38)/t18-,25+,26+/m1/s1 AXVHCKACGKXESV-LROUJFHJSA-N 50279643 CHEMBL4173234 Mu-type opioid receptor Cavia cutleri 1.1 ChEMBL 10.1021/acsmedchemlett.7b00347 10.7270/Q2251MRN 29152051 Van der Poorten, O; Van Den Hauwe, R; Eiselt, E; Betti, C; Guillemyn, K; Chung, NN; Hallé, F; Bihel, F; Schiller, PW; Tourwé, D; Sarret, P; Gendron, L; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279643&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145949299 406793884 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50988273 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O InChI=1S/C40H50N8O10/c1-23(44-37(55)29(41)18-25-9-13-27(50)14-10-25)36(54)46-30(19-24-6-3-2-4-7-24)38(56)43-21-34(52)45-31(20-26-11-15-28(51)16-12-26)40(58)48-17-5-8-33(48)39(57)47-32(22-49)35(42)53/h2-4,6-7,9-16,23,29-33,49-51H,5,8,17-22,41H2,1H3,(H2,42,53)(H,43,56)(H,44,55)(H,45,52)(H,46,54)(H,47,57)/t23-,29+,30+,31+,32+,33+/m1/s1 FHZPGIUBXYVUOY-VWGYHWLBSA-N 50059841 (S)-1-[(S)-2-[2-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid ((S)-1-carbamoyl-2-hydroxy-ethyl)-amide::(S)-2-Amino-N-{(R)-1-[(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethylcarbamoyl]-ethyl}-3-(4-hydroxy-phenyl)-propionamide::1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide::1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide (Dermorphin)::1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide(Dermorphin)::CHEMBL278789::DERMORPHIN::Dermorphin;1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide::H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2::Tyr-Ala-Phe-Gly-Tyr-Pro-Ser::YAFGYPS-NH2 Mu-type opioid receptor Cavia cutleri 1.1 ChEMBL 10.1021/acsmedchemlett.7b00347 10.7270/Q2251MRN 29152051 Van der Poorten, O; Van Den Hauwe, R; Eiselt, E; Betti, C; Guillemyn, K; Chung, NN; Hallé, F; Bihel, F; Schiller, PW; Tourwé, D; Sarret, P; Gendron, L; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059841 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059841&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5485199 103955620 CHEMBL278789 ZINC95548678 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50988313 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@H]1Cc2ccccc2CN(CC(N)=O)C1=O InChI=1S/C24H29N5O5/c1-14(27-23(33)19(25)10-15-6-8-18(30)9-7-15)22(32)28-20-11-16-4-2-3-5-17(16)12-29(24(20)34)13-21(26)31/h2-9,14,19-20,30H,10-13,25H2,1H3,(H2,26,31)(H,27,33)(H,28,32)/t14-,19+,20+/m1/s1 BFSKEMNZFARJEG-UAOJZALGSA-N 50279646 CHEMBL4172559 Mu-type opioid receptor Cavia cutleri 50 ChEMBL 10.1021/acsmedchemlett.7b00347 10.7270/Q2251MRN 29152051 Van der Poorten, O; Van Den Hauwe, R; Eiselt, E; Betti, C; Guillemyn, K; Chung, NN; Hallé, F; Bihel, F; Schiller, PW; Tourwé, D; Sarret, P; Gendron, L; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279646 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279646&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 11634134 406793887 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50988324 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H]1Cc2c(CN(CC(N)=O)C1=O)ccc1ccccc21 InChI=1S/C33H42N8O5/c1-18-12-22(42)13-19(2)24(18)14-26(34)30(44)39-27(8-5-11-38-33(36)37)31(45)40-28-15-25-21(16-41(32(28)46)17-29(35)43)10-9-20-6-3-4-7-23(20)25/h3-4,6-7,9-10,12-13,26-28,42H,5,8,11,14-17,34H2,1-2H3,(H2,35,43)(H,39,44)(H,40,45)(H4,36,37,38)/t26-,27+,28-/m0/s1 VRLMPUXFAPNKKK-IARZGTGTSA-N 50279649 CHEMBL4165323 Mu-type opioid receptor Cavia cutleri 0.252000 ChEMBL 10.1021/acsmedchemlett.7b00347 10.7270/Q2251MRN 29152051 Van der Poorten, O; Van Den Hauwe, R; Eiselt, E; Betti, C; Guillemyn, K; Chung, NN; Hallé, F; Bihel, F; Schiller, PW; Tourwé, D; Sarret, P; Gendron, L; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279649 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279649&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145963745 406793890 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50988325 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H]1Cc2ccc3ccccc3c2CN(CC(N)=O)C1=O InChI=1S/C33H42N8O5/c1-18-12-22(42)13-19(2)24(18)15-26(34)30(44)39-27(8-5-11-38-33(36)37)31(45)40-28-14-21-10-9-20-6-3-4-7-23(20)25(21)16-41(32(28)46)17-29(35)43/h3-4,6-7,9-10,12-13,26-28,42H,5,8,11,14-17,34H2,1-2H3,(H2,35,43)(H,39,44)(H,40,45)(H4,36,37,38)/t26-,27+,28-/m0/s1 YIFWHJCELZDCAJ-IARZGTGTSA-N 50279644 CHEMBL4161890 Mu-type opioid receptor Cavia cutleri 21 ChEMBL 10.1021/acsmedchemlett.7b00347 10.7270/Q2251MRN 29152051 Van der Poorten, O; Van Den Hauwe, R; Eiselt, E; Betti, C; Guillemyn, K; Chung, NN; Hallé, F; Bihel, F; Schiller, PW; Tourwé, D; Sarret, P; Gendron, L; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279644&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145960193 406793885 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50988338 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(N)=O InChI=1S/C23H29N5O5/c1-14(27-22(32)18(24)11-16-7-9-17(29)10-8-16)21(31)28-19(23(33)26-13-20(25)30)12-15-5-3-2-4-6-15/h2-10,14,18-19,29H,11-13,24H2,1H3,(H2,25,30)(H,26,33)(H,27,32)(H,28,31)/t14-,18+,19+/m1/s1 JWZLANUHRXGDET-CCKFTAQKSA-N 50279650 CHEMBL349816 Mu-type opioid receptor Cavia cutleri 35 ChEMBL 10.1021/acsmedchemlett.7b00347 10.7270/Q2251MRN 29152051 Van der Poorten, O; Van Den Hauwe, R; Eiselt, E; Betti, C; Guillemyn, K; Chung, NN; Hallé, F; Bihel, F; Schiller, PW; Tourwé, D; Sarret, P; Gendron, L; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279650 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279650&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 132901 406793891 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50988341 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H]1Cc2ccccc2CN(CC(N)=O)C1=O InChI=1S/C29H40N8O5/c1-16-10-20(38)11-17(2)21(16)13-22(30)26(40)35-23(8-5-9-34-29(32)33)27(41)36-24-12-18-6-3-4-7-19(18)14-37(28(24)42)15-25(31)39/h3-4,6-7,10-11,22-24,38H,5,8-9,12-15,30H2,1-2H3,(H2,31,39)(H,35,40)(H,36,41)(H4,32,33,34)/t22-,23+,24-/m0/s1 ORYLQLGPWPORPN-VXNXHJTFSA-N 50346330 (R)-N-((S)-2-(2-amino-2-oxoethyl)-3-oxo-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-yl)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)-5-guanidinopentanamide::CHEMBL1782140 Mu-type opioid receptor Cavia cutleri 0.320000 ChEMBL 10.1021/acsmedchemlett.7b00347 10.7270/Q2251MRN 29152051 Van der Poorten, O; Van Den Hauwe, R; Eiselt, E; Betti, C; Guillemyn, K; Chung, NN; Hallé, F; Bihel, F; Schiller, PW; Tourwé, D; Sarret, P; Gendron, L; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346330&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 52937468 131349261 CHEMBL1782140 ZINC71295052 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 50988351 C[C@@H](N(C)C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@H]1Cc2c(CN(CC(N)=O)C1=O)ccc1ccccc21 InChI=1S/C31H37N5O5/c1-17-11-22(37)12-18(2)24(17)13-26(32)30(40)35(4)19(3)29(39)34-27-14-25-21(15-36(31(27)41)16-28(33)38)10-9-20-7-5-6-8-23(20)25/h5-12,19,26-27,37H,13-16,32H2,1-4H3,(H2,33,38)(H,34,39)/t19-,26+,27+/m1/s1 FYXNDOATHYRSML-VHEIIQRDSA-N 50279648 CHEMBL4166388 Mu-type opioid receptor Cavia cutleri 0.430000 ChEMBL 10.1021/acsmedchemlett.7b00347 10.7270/Q2251MRN 29152051 Van der Poorten, O; Van Den Hauwe, R; Eiselt, E; Betti, C; Guillemyn, K; Chung, NN; Hallé, F; Bihel, F; Schiller, PW; Tourwé, D; Sarret, P; Gendron, L; Ballet, S Vrije Universiteit Brussel http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279648 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279648&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145952667 406793889 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51039431 COc1ccc(Nc2ccc3CC4C(C)C(C)(CCN4CC4CC4)c3c2)cc1 InChI=1S/C25H32N2O/c1-17-24-14-19-6-7-21(26-20-8-10-22(28-3)11-9-20)15-23(19)25(17,2)12-13-27(24)16-18-4-5-18/h6-11,15,17-18,24,26H,4-5,12-14,16H2,1-3H3 DJFFPOVRKTXBHV-UHFFFAOYSA-N 50458137 CHEMBL4210742 Mu-type opioid receptor Cavia cutleri 0.470000 ChEMBL 10.1016/j.ejmech.2018.02.046 10.7270/Q2QR50SX 29477074 Turnaturi, R; Marrazzo, A; Parenti, C; Pasquinucci, L University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50458137 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50458137&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 75006383 433925402 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51039432 CCC12CCN(CC3CC3)C(C1C)C(=O)c1ccc(cc21)C(N)=O InChI=1S/C20H26N2O2/c1-3-20-8-9-22(11-13-4-5-13)17(12(20)2)18(23)15-7-6-14(19(21)24)10-16(15)20/h6-7,10,12-13,17H,3-5,8-9,11H2,1-2H3,(H2,21,24) NBEPKKBOGWVFFT-UHFFFAOYSA-N 50254563 3-Cyclopropylmethyl-6-ethyl-11-methyl-1-oxo-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid amide::CHEMBL461229 Mu-type opioid receptor Cavia cutleri 1.2 ChEMBL 10.1016/j.ejmech.2018.02.046 10.7270/Q2QR50SX 29477074 Turnaturi, R; Marrazzo, A; Parenti, C; Pasquinucci, L University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50254563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50254563&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44570065 104106759 CHEMBL461229 ZINC13490123 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51039898 CC1C2Cc3ccc(NC=O)cc3C1(C)CCN2CC1CC1 InChI=1S/C19H26N2O/c1-13-18-9-15-5-6-16(20-12-22)10-17(15)19(13,2)7-8-21(18)11-14-3-4-14/h5-6,10,12-14,18H,3-4,7-9,11H2,1-2H3,(H,20,22) GRERSJXDCJKLDU-UHFFFAOYSA-N 50458141 CHEMBL4204304 Mu-type opioid receptor Cavia cutleri 1.9 ChEMBL 10.1016/j.ejmech.2018.02.046 10.7270/Q2QR50SX 29477074 Turnaturi, R; Marrazzo, A; Parenti, C; Pasquinucci, L University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50458141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50458141&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 6420605 433925406 C06049 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51039899 CCC12CCN(CC3CC3)C(C1C)C(=O)c1ccc(NC=O)cc21 InChI=1S/C20H26N2O2/c1-3-20-8-9-22(11-14-4-5-14)18(13(20)2)19(24)16-7-6-15(21-12-23)10-17(16)20/h6-7,10,12-14,18H,3-5,8-9,11H2,1-2H3,(H,21,23) OIISUVOSYUTARN-UHFFFAOYSA-N 50458142 CHEMBL4208635 Mu-type opioid receptor Cavia cutleri 6.1 ChEMBL 10.1016/j.ejmech.2018.02.046 10.7270/Q2QR50SX 29477074 Turnaturi, R; Marrazzo, A; Parenti, C; Pasquinucci, L University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50458142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50458142&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 74986629 433925407 C06049 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51041275 C[C@H]1[C@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C18H25NO/c1-12-17-9-14-5-6-15(20)10-16(14)18(12,2)7-8-19(17)11-13-3-4-13/h5-6,10,12-13,17,20H,3-4,7-9,11H2,1-2H3/t12-,17?,18-/m0/s1 YQYVFVRQLZMJKJ-PEYLTSRESA-N 50083926 (6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::(SSR)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyclo[9.1.1.0*3,8*]trideca-3(8),4,6-trien-6-ol(cyclazocine)::(cyclazocine)2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid::10-cyclopropylmethyl-1,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol(Cyclazocine)::3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol (cyclazocine)::3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Cyclazocine)::3-Cyclopropylmethyl-8-hydroxy-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocinium::3-Cyclopropylmethyl-8-hydroxy-6,11-dimethyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one ((-)cyclazocine)::BDBM50451129::CHEMBL3085528::CYCLAZOCINE Mu-type opioid receptor Cavia cutleri 0.100000 ChEMBL 10.1016/j.ejmech.2018.02.046 10.7270/Q2QR50SX 29477074 Turnaturi, R; Marrazzo, A; Parenti, C; Pasquinucci, L University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083926 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083926&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10016044 103983527 CHEMBL3085528 ZINC01699599 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51041276 C[C@H]1[C@H]2Cc3ccc(Nc4ccccc4)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C24H30N2/c1-17-23-14-19-10-11-21(25-20-6-4-3-5-7-20)15-22(19)24(17,2)12-13-26(23)16-18-8-9-18/h3-7,10-11,15,17-18,23,25H,8-9,12-14,16H2,1-2H3/t17-,23?,24-/m0/s1 FUMBLBJFVJXVBV-LZCUNHEZSA-N 50085020 ((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-phenyl-amine::(3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-yl)-phenyl-amine::CHEMBL2367916 Mu-type opioid receptor Cavia cutleri 1.1 ChEMBL 10.1016/j.ejmech.2018.02.046 10.7270/Q2QR50SX 29477074 Turnaturi, R; Marrazzo, A; Parenti, C; Pasquinucci, L University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085020&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73351393 103984503 CHEMBL2367916 ZINC13493416 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51041278 CCC12CCN(CC3CC3)C(C1C)C(=O)c1ccc(O)cc21 InChI=1S/C19H25NO2/c1-3-19-8-9-20(11-13-4-5-13)17(12(19)2)18(22)15-7-6-14(21)10-16(15)19/h6-7,10,12-13,17,21H,3-5,8-9,11H2,1-2H3 SEJUQQOPVAUETF-UHFFFAOYSA-N 50045114 3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,4,5,6-tetrahydro-2H-2,6-methano-benzo[d]azocin-1-one::CHEMBL55033::EKC Mu-type opioid receptor Cavia cutleri 0.780000 ChEMBL 10.1016/j.ejmech.2018.02.046 10.7270/Q2QR50SX 29477074 Turnaturi, R; Marrazzo, A; Parenti, C; Pasquinucci, L University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045114 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045114&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 4491166 103976212 CHEMBL55033 ZINC04102216 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51041310 CC1C2Cc3ccc(Nc4cccnc4)cc3C1(C)CCN2CC1CC1 InChI=1S/C23H29N3/c1-16-22-12-18-7-8-19(25-20-4-3-10-24-14-20)13-21(18)23(16,2)9-11-26(22)15-17-5-6-17/h3-4,7-8,10,13-14,16-17,22,25H,5-6,9,11-12,15H2,1-2H3 OHSQUTOUXRPUSB-UHFFFAOYSA-N 50458152 CHEMBL4207167 Mu-type opioid receptor Cavia cutleri 0.640000 ChEMBL 10.1016/j.ejmech.2018.02.046 10.7270/Q2QR50SX 29477074 Turnaturi, R; Marrazzo, A; Parenti, C; Pasquinucci, L University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50458152 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50458152&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 75006294 433925417 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51041312 C[C@H]1[C@H]2Cc3ccc(N)cc3[C@@]1(C)CCN2CC1CC1 InChI=1S/C18H26N2/c1-12-17-9-14-5-6-15(19)10-16(14)18(12,2)7-8-20(17)11-13-3-4-13/h5-6,10,12-13,17H,3-4,7-9,11,19H2,1-2H3/t12-,17+,18-/m0/s1 STNPURITMRUHGJ-RZAIGCCYSA-N 50092176 3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ylamine::CHEMBL332017 Mu-type opioid receptor Cavia cutleri 1.8 ChEMBL 10.1016/j.ejmech.2018.02.046 10.7270/Q2QR50SX 29477074 Turnaturi, R; Marrazzo, A; Parenti, C; Pasquinucci, L University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092176&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 12994686 103990366 CHEMBL332017 ZINC13493411 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51041313 C[C@H]1[C@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2C[C@@H]1CCCO1 InChI=1S/C19H27NO2/c1-13-18-10-14-5-6-15(21)11-17(14)19(13,2)7-8-20(18)12-16-4-3-9-22-16/h5-6,11,13,16,18,21H,3-4,7-10,12H2,1-2H3/t13-,16-,18+,19-/m0/s1 NLKLXMMOJZHSCB-IVJVFBROSA-N 50007102 6,11-Dimethyl-3-(tetrahydro-furan-2-ylmethyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL79470::MR-2034 Mu-type opioid receptor Cavia cutleri 0.170000 ChEMBL 10.1016/j.ejmech.2018.02.046 10.7270/Q2QR50SX 29477074 Turnaturi, R; Marrazzo, A; Parenti, C; Pasquinucci, L University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007102 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007102&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 68196155 103920385 CHEMBL79470 ZINC13493451 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51041315 CC1C2Cc3ccc(O)cc3C1(C)CCN2CC1CC1 InChI=1S/C18H25NO/c1-12-17-9-14-5-6-15(20)10-16(14)18(12,2)7-8-19(17)11-13-3-4-13/h5-6,10,12-13,17,20H,3-4,7-9,11H2,1-2H3 YQYVFVRQLZMJKJ-UHFFFAOYSA-N 50018731 (Cyclazocine) 3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::(cyclazocine)2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid::10-cyclopropylmethyl-1,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol(Cyclazocine)::3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol (cyclazocine)::3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Cyclazocine)::3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CYCLAZOCINE (-)::Cyclazocine (+) Mu-type opioid receptor Cavia cutleri 0.320000 ChEMBL 10.1016/j.ejmech.2018.02.046 10.7270/Q2QR50SX 29477074 Turnaturi, R; Marrazzo, A; Parenti, C; Pasquinucci, L University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018731 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018731&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 19143 103929808 1604 ZINC03830613 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51041317 CC1C2Cc3ccc(cc3C1(C)CCN2CC1CC1)C(N)=O InChI=1S/C19H26N2O/c1-12-17-10-14-5-6-15(18(20)22)9-16(14)19(12,2)7-8-21(17)11-13-3-4-13/h5-6,9,12-13,17H,3-4,7-8,10-11H2,1-2H3,(H2,20,22) FAVQVALXVLMHLE-UHFFFAOYSA-N 50101160 3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid amide::CHEMBL297428 Mu-type opioid receptor Cavia cutleri 0.410000 ChEMBL 10.1016/j.ejmech.2018.02.046 10.7270/Q2QR50SX 29477074 Turnaturi, R; Marrazzo, A; Parenti, C; Pasquinucci, L University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101160 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101160&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9839245 103997855 CHEMBL297428 ZINC33980697 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51041322 C[C@H]1[C@H]2Cc3ccc(NC=O)cc3[C@]1(C)CCN2CC1CC1 InChI=1S/C19H26N2O/c1-13-18-9-15-5-6-16(20-12-22)10-17(15)19(13,2)7-8-21(18)11-14-3-4-14/h5-6,10,12-14,18H,3-4,7-9,11H2,1-2H3,(H,20,22)/t13-,18+,19+/m0/s1 GRERSJXDCJKLDU-MJXNMMHHSA-N 50458143 CHEMBL4215981 Mu-type opioid receptor Cavia cutleri 1.1 ChEMBL 10.1016/j.ejmech.2018.02.046 10.7270/Q2QR50SX 29477074 Turnaturi, R; Marrazzo, A; Parenti, C; Pasquinucci, L University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50458143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50458143&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 20836691 433925408 C06049 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51105029 FCC[C@@H]1Cc2ccccc2C2(CC[C@@H](CC2)N2CCN(CC2)C2CCCCC2)O1 InChI=1S/C26H39FN2O/c27-15-12-24-20-21-6-4-5-9-25(21)26(30-24)13-10-23(11-14-26)29-18-16-28(17-19-29)22-7-2-1-3-8-22/h4-6,9,22-24H,1-3,7-8,10-20H2/t23-,24-,26?/m1/s1 BXYLBPZPCRRRIX-LBHOTPKDSA-N 50450636 CHEMBL4170683 Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/acs.jmedchem.8b01183 10.7270/Q2M32Z9M 30350997 Bergkemper, M; Kronenberg, E; Thum, S; Börgel, F; Daniliuc, C; Schepmann, D; Nieto, FR; Brust, P; Reinoso, RF; Alvarez, I; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50450636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50450636&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145950456 433920043 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51105111 O[C@H]1Cc2ccccc2C2(CC[C@@H](CC2)N2CCN(CC2)C2CCCCC2)O1 InChI=1S/C24H36N2O2/c27-23-18-19-6-4-5-9-22(19)24(28-23)12-10-21(11-13-24)26-16-14-25(15-17-26)20-7-2-1-3-8-20/h4-6,9,20-21,23,27H,1-3,7-8,10-18H2/t21-,23-,24?/m1/s1 FLCVJBOJFYGFGM-UMBAGBCYSA-N 50450645 CHEMBL4169479 Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1021/acs.jmedchem.8b01183 10.7270/Q2M32Z9M 30350997 Bergkemper, M; Kronenberg, E; Thum, S; Börgel, F; Daniliuc, C; Schepmann, D; Nieto, FR; Brust, P; Reinoso, RF; Alvarez, I; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50450645 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50450645&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145954168 433920051 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51105112 CCOC(=O)C[C@H]1Cc2ccccc2C2(CC[C@@H](CC2)N2CCN(CC2)C2CCCCC2)O1 InChI=1S/C28H42N2O3/c1-2-32-27(31)21-25-20-22-8-6-7-11-26(22)28(33-25)14-12-24(13-15-28)30-18-16-29(17-19-30)23-9-4-3-5-10-23/h6-8,11,23-25H,2-5,9-10,12-21H2,1H3/t24-,25-,28?/m1/s1 LCJJDFOHUJHXSV-RCUHSBBRSA-N 50450633 CHEMBL4159233 Mu-type opioid receptor Cavia cutleri 458 ChEMBL 10.1021/acs.jmedchem.8b01183 10.7270/Q2M32Z9M 30350997 Bergkemper, M; Kronenberg, E; Thum, S; Börgel, F; Daniliuc, C; Schepmann, D; Nieto, FR; Brust, P; Reinoso, RF; Alvarez, I; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50450633 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50450633&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145957598 433920040 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51105113 FCC[C@H]1Cc2ccccc2C2(CC[C@@H](CC2)N2CCN(CC2)C2CCCCC2)O1 InChI=1S/C26H39FN2O/c27-15-12-24-20-21-6-4-5-9-25(21)26(30-24)13-10-23(11-14-26)29-18-16-28(17-19-29)22-7-2-1-3-8-22/h4-6,9,22-24H,1-3,7-8,10-20H2/t23-,24-,26?/m0/s1 BXYLBPZPCRRRIX-OKHNBNEASA-N 50450646 CHEMBL4170858 Mu-type opioid receptor Cavia cutleri 434 ChEMBL 10.1021/acs.jmedchem.8b01183 10.7270/Q2M32Z9M 30350997 Bergkemper, M; Kronenberg, E; Thum, S; Börgel, F; Daniliuc, C; Schepmann, D; Nieto, FR; Brust, P; Reinoso, RF; Alvarez, I; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50450646 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50450646&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145949157 433920052 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51132771 O=C1N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](Cc2ccccc2)C(=O)N2CCC[C@H]12 InChI=1S/C34H35N5O4/c40-31-27(18-22-10-3-1-4-11-22)37-33(42)30-16-9-17-39(30)34(43)29(19-23-12-5-2-6-13-23)38-32(41)28(36-31)20-24-21-35-26-15-8-7-14-25(24)26/h1-8,10-15,21,27-30,35H,9,16-20H2,(H,36,40)(H,37,42)(H,38,41)/t27-,28-,29-,30+/m0/s1 GIZJWWQFOGQPRY-GCXHJFECSA-N 50268462 CHEMBL506616::c[L-Phe-D-pro-L-Phe-L-trp] Mu-type opioid receptor Cavia cutleri 260 ChEMBL 10.1016/j.ejmech.2017.10.012 10.7270/Q2V98BQ2 29107424 Helal, MA; Habib, ES; Chittiboyina, AG University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50268462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50268462&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44583372 104114853 CHEMBL506616 ZINC03989600 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51162851 Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2c(NC(=O)c4ccc6cc(C=O)c(C=O)cc6c4)cccc2c1C[C@@]35O InChI=1S/C39H33N3O6/c43-18-25-12-21-6-7-23(13-24(21)14-26(25)19-44)37(46)40-29-3-1-2-27-28-16-39(47)31-15-22-8-9-30(45)35-32(22)38(39,10-11-42(31)17-20-4-5-20)36(48-35)34(28)41-33(27)29/h1-3,6-9,12-14,18-20,31,36,41,45,47H,4-5,10-11,15-17H2,(H,40,46)/t31-,36+,38+,39-/m1/s1 FAAITYPIDMPBCP-GSMBKCQZSA-N 50476388 CHEMBL2113281 Mu-type opioid receptor Cavia cutleri 20 ChEMBL 10.1021/jm061194h 10.7270/Q2VX0K9R 17555306 Haris, SP; Zhang, Y; Le Bourdonnec, B; McCurdy, CR; Portoghese, PS University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476388 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476388&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16735664 433943653 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51157091 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 3.5 ChEMBL 10.1021/jm010576e 10.7270/Q2WS8X0T 11960505 Takayama, H; Ishikawa, H; Kurihara, M; Kitajima, M; Aimi, N; Ponglux, D; Koyama, F; Matsumoto, K; Moriyama, T; Yamamoto, LT; Watanabe, K; Murayama, T; Horie, S Chiba University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51157092 CC[C@@H]1CN2CC[C@]3(Nc4cccc(OC)c4C3=O)[C@@H]2C[C@@H]1\C(=C/OC)C(=O)OC InChI=1S/C23H30N2O5/c1-5-14-12-25-10-9-23(19(25)11-15(14)16(13-28-2)22(27)30-4)21(26)20-17(24-23)7-6-8-18(20)29-3/h6-8,13-15,19,24H,5,9-12H2,1-4H3/b16-13+/t14-,15+,19+,23+/m1/s1 BAEJBRCYKACTAA-WGUOAFTMSA-N 50474150 CHEMBL58362 Mu-type opioid receptor Cavia cutleri 0.087096 ChEMBL 10.1021/jm010576e 10.7270/Q2WS8X0T 11960505 Takayama, H; Ishikawa, H; Kurihara, M; Kitajima, M; Aimi, N; Ponglux, D; Koyama, F; Matsumoto, K; Moriyama, T; Yamamoto, LT; Watanabe, K; Murayama, T; Horie, S Chiba University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50474150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50474150&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search EIG 7T2G 44301701 433941415 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51157095 CC[C@@H]1CN2CCc3c([nH]c4cccc(O)c34)[C@@H]2C[C@@H]1\C(=C/OC)C(=O)OC InChI=1S/C22H28N2O4/c1-4-13-11-24-9-8-14-20-17(6-5-7-19(20)25)23-21(14)18(24)10-15(13)16(12-27-2)22(26)28-3/h5-7,12-13,15,18,23,25H,4,8-11H2,1-3H3/b16-12+/t13-,15+,18+/m1/s1 IIRZCWUQUBSIPF-XZNUVMSOSA-N 50474151 CHEMBL292521 Mu-type opioid receptor Cavia cutleri 12 ChEMBL 10.1021/jm010576e 10.7270/Q2WS8X0T 11960505 Takayama, H; Ishikawa, H; Kurihara, M; Kitajima, M; Aimi, N; Ponglux, D; Koyama, F; Matsumoto, K; Moriyama, T; Yamamoto, LT; Watanabe, K; Murayama, T; Horie, S Chiba University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50474151 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50474151&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10927114 433941416 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51157098 CC[C@@H]1CN2CCc3c([nH]c4ccccc34)[C@@H]2C[C@@H]1\C(=C/OC)C(=O)OC InChI=1S/C22H28N2O3/c1-4-14-12-24-10-9-16-15-7-5-6-8-19(15)23-21(16)20(24)11-17(14)18(13-26-2)22(25)27-3/h5-8,13-14,17,20,23H,4,9-12H2,1-3H3/b18-13+/t14-,17+,20+/m1/s1 NMLUOJBSAYAYEM-QALMDFCDSA-N 50474149 CHEBI:70073::Corynanrheidine Mu-type opioid receptor Cavia cutleri 72 ChEMBL 10.1021/jm010576e 10.7270/Q2WS8X0T 11960505 Takayama, H; Ishikawa, H; Kurihara, M; Kitajima, M; Aimi, N; Ponglux, D; Koyama, F; Matsumoto, K; Moriyama, T; Yamamoto, LT; Watanabe, K; Murayama, T; Horie, S Chiba University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50474149 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50474149&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3000341 433941414 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51157099 CC[C@@H]1CN2CCc3c([nH]c4cccc(OC)c34)[C@@H]2C[C@@H]1\C(=C/OC)C(=O)OC InChI=1S/C23H30N2O4/c1-5-14-12-25-10-9-15-21-18(7-6-8-20(21)28-3)24-22(15)19(25)11-16(14)17(13-27-2)23(26)29-4/h6-8,13-14,16,19,24H,5,9-12H2,1-4H3/b17-13+/t14-,16+,19+/m1/s1 LELBFTMXCIIKKX-QVRQZEMUSA-N 50474152 CHEBI:6956::CHEMBL299031 Mu-type opioid receptor Cavia cutleri 7.2 ChEMBL 10.1021/jm010576e 10.7270/Q2WS8X0T 11960505 Takayama, H; Ishikawa, H; Kurihara, M; Kitajima, M; Aimi, N; Ponglux, D; Koyama, F; Matsumoto, K; Moriyama, T; Yamamoto, LT; Watanabe, K; Murayama, T; Horie, S Chiba University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50474152 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50474152&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3034396 433941417 C09226 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51157104 CC[C@@H]1CN2CC[C@@]3(O)C(=Nc4cccc(OC)c34)[C@@H]2C[C@@H]1\C(=C/OC)C(=O)OC InChI=1S/C23H30N2O5/c1-5-14-12-25-10-9-23(27)20-17(7-6-8-19(20)29-3)24-21(23)18(25)11-15(14)16(13-28-2)22(26)30-4/h6-8,13-15,18,27H,5,9-12H2,1-4H3/b16-13+/t14-,15+,18+,23+/m1/s1 RYENLSMHLCNXJT-CYXFISRXSA-N 50474153 CHEMBL61630 Mu-type opioid receptor Cavia cutleri 13 ChEMBL 10.1021/jm010576e 10.7270/Q2WS8X0T 11960505 Takayama, H; Ishikawa, H; Kurihara, M; Kitajima, M; Aimi, N; Ponglux, D; Koyama, F; Matsumoto, K; Moriyama, T; Yamamoto, LT; Watanabe, K; Murayama, T; Horie, S Chiba University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50474153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50474153&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44301524 433941418 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51196376 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CN\C(=N/C[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC1=O)C(N)=O)N1CCCCC1 InChI=1S/C32H43N9O6/c33-23(15-21-9-11-22(42)12-10-21)29(45)40-26-18-37-32(41-13-5-2-6-14-41)36-17-25(28(34)44)39-31(47)24(16-20-7-3-1-4-8-20)38-27(43)19-35-30(26)46/h1,3-4,7-12,23-26,42H,2,5-6,13-19,33H2,(H2,34,44)(H,35,46)(H,36,37)(H,38,43)(H,39,47)(H,40,45)/t23-,24-,25-,26+/m0/s1 AUFPKYMBJJTQQY-ASDGIDEWSA-N 50492486 CHEMBL2402930 Mu-type opioid receptor Cavia cutleri 398 ChEMBL 10.1021/jm4008592 10.7270/Q2571FXF 23822516 Touati-Jallabe, Y; Bojnik, E; Legrand, B; Mauchauffée, E; Chung, NN; Schiller, PW; Benyhe, S; Averlant-Petit, MC; Martinez, J; Hernandez, JF Universit£ Montpellier 1 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492486 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492486&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71761638 433959751 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51196377 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CN\C(N)=N/C[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC1=O)C(N)=O InChI=1S/C27H35N9O6/c28-18(10-16-6-8-17(37)9-7-16)24(40)36-21-13-33-27(30)32-12-20(23(29)39)35-26(42)19(11-15-4-2-1-3-5-15)34-22(38)14-31-25(21)41/h1-9,18-21,37H,10-14,28H2,(H2,29,39)(H,31,41)(H,34,38)(H,35,42)(H,36,40)(H3,30,32,33)/t18-,19-,20-,21+/m0/s1 ZZRVIJZHPSFBMK-XSDIEEQYSA-N 50492489 CHEMBL2402938 Mu-type opioid receptor Cavia cutleri 244 ChEMBL 10.1021/jm4008592 10.7270/Q2571FXF 23822516 Touati-Jallabe, Y; Bojnik, E; Legrand, B; Mauchauffée, E; Chung, NN; Schiller, PW; Benyhe, S; Averlant-Petit, MC; Martinez, J; Hernandez, JF Universit£ Montpellier 1 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492489 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492489&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71765059 433959754 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51196378 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CNC(=S)NC[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC1=O)C(N)=O InChI=1S/C27H34N8O6S/c28-18(10-16-6-8-17(36)9-7-16)24(39)35-21-13-32-27(42)31-12-20(23(29)38)34-26(41)19(11-15-4-2-1-3-5-15)33-22(37)14-30-25(21)40/h1-9,18-21,36H,10-14,28H2,(H2,29,38)(H,30,40)(H,33,37)(H,34,41)(H,35,39)(H2,31,32,42)/t18-,19-,20-,21+/m0/s1 MNTOUKHSDQFMMF-XSDIEEQYSA-N 50492490 CHEMBL2402936 Mu-type opioid receptor Cavia cutleri 1.8 ChEMBL 10.1021/jm4008592 10.7270/Q2571FXF 23822516 Touati-Jallabe, Y; Bojnik, E; Legrand, B; Mauchauffée, E; Chung, NN; Schiller, PW; Benyhe, S; Averlant-Petit, MC; Martinez, J; Hernandez, JF Universit£ Montpellier 1 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492490 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492490&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71764843 433959755 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51196444 CN\C1=N\C[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H](CN1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O InChI=1S/C28H37N9O6/c1-31-28-33-13-21(24(30)40)36-27(43)20(12-16-5-3-2-4-6-16)35-23(39)15-32-26(42)22(14-34-28)37-25(41)19(29)11-17-7-9-18(38)10-8-17/h2-10,19-22,38H,11-15,29H2,1H3,(H2,30,40)(H,32,42)(H,35,39)(H,36,43)(H,37,41)(H2,31,33,34)/t19-,20-,21-,22+/m0/s1 IRLBHQXMZHCSMJ-MYGLTJDJSA-N 50492493 CHEMBL2402939 Mu-type opioid receptor Cavia cutleri 42 ChEMBL 10.1021/jm4008592 10.7270/Q2571FXF 23822516 Touati-Jallabe, Y; Bojnik, E; Legrand, B; Mauchauffée, E; Chung, NN; Schiller, PW; Benyhe, S; Averlant-Petit, MC; Martinez, J; Hernandez, JF Universit£ Montpellier 1 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492493&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 136260442 433959758 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51196454 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O InChI=1S/C28H37N5O7/c1-17(2)12-23(28(39)40)33-27(38)22(14-18-6-4-3-5-7-18)32-25(36)16-30-24(35)15-31-26(37)21(29)13-19-8-10-20(34)11-9-19/h3-11,17,21-23,34H,12-16,29H2,1-2H3,(H,30,35)(H,31,37)(H,32,36)(H,33,38)(H,39,40)/t21-,22-,23-/m0/s1 URLZCHNOLZSCCA-VABKMULXSA-N 50001465 (S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::([Leu]-enkephalin)2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::(enkephalin)2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-1-oxo-3-phenyl-propylamino]-4-methyl-pentanoic acid::2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::2-[1-[1-amino-2-(4-hydroxyphenyl)-(1S)-ethylcarboxamidomethylcarboxamidomethylcarboxamido]-2-phenyl-(1S)-ethylcarboxamido]-4-methyl-(2S)-pentanoic acid::2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid::2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid(Enkephalin)::2-{1-[1-amino-2-(4-hydroxyphenyl)ethylcarboxamidomethylcarboxamidomethylcarboxamido]-2-phenylethylcarboxamido}-4-methylpentanoic acid::CHEMBL8234::ENKEPHALIN::Leu-ENKEPHALIN::Leu5-Enkephalin::Tyr-Gly-Gly-Phe-Leu-OH Mu-type opioid receptor Cavia cutleri 246 ChEMBL 10.1021/jm4008592 10.7270/Q2571FXF 23822516 Touati-Jallabe, Y; Bojnik, E; Legrand, B; Mauchauffée, E; Chung, NN; Schiller, PW; Benyhe, S; Averlant-Petit, MC; Martinez, J; Hernandez, JF Universit£ Montpellier 1 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001465&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 461776 103915930 CHEMBL8234 ZINC14952116 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51196455 CS\C1=N\C[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H](CN1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O InChI=1S/C28H36N8O6S/c1-43-28-32-13-21(24(30)39)35-27(42)20(12-16-5-3-2-4-6-16)34-23(38)15-31-26(41)22(14-33-28)36-25(40)19(29)11-17-7-9-18(37)10-8-17/h2-10,19-22,37H,11-15,29H2,1H3,(H2,30,39)(H,31,41)(H,32,33)(H,34,38)(H,35,42)(H,36,40)/t19-,20-,21-,22+/m0/s1 SFIREGVLUZEACS-MYGLTJDJSA-N 50492487 CHEMBL2402937 Mu-type opioid receptor Cavia cutleri 18 ChEMBL 10.1021/jm4008592 10.7270/Q2571FXF 23822516 Touati-Jallabe, Y; Bojnik, E; Legrand, B; Mauchauffée, E; Chung, NN; Schiller, PW; Benyhe, S; Averlant-Petit, MC; Martinez, J; Hernandez, JF Universit£ Montpellier 1 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492487 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492487&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71765058 433959752 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51195391 CC[C@@H]1CN2CC[C@@]3(O)C(=Nc4cccc(OC)c34)[C@@H]2C[C@@H]1\C(=C/OC)C(=O)OC InChI=1S/C23H30N2O5/c1-5-14-12-25-10-9-23(27)20-17(7-6-8-19(20)29-3)24-21(23)18(25)11-15(14)16(13-28-2)22(26)30-4/h6-8,13-15,18,27H,5,9-12H2,1-4H3/b16-13+/t14-,15+,18+,23+/m1/s1 RYENLSMHLCNXJT-CYXFISRXSA-N 50474153 CHEMBL61630 Mu-type opioid receptor Cavia cutleri 13 ChEMBL 10.1021/jm400143z 10.7270/Q2FT8PZS 23517479 Raffa, RB; Beckett, JR; Brahmbhatt, VN; Ebinger, TM; Fabian, CA; Nixon, JR; Orlando, ST; Rana, CA; Tejani, AH; Tomazic, RJ Temple University School of Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50474153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50474153&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44301524 433941418 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51195394 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 3.5 ChEMBL 10.1021/jm400143z 10.7270/Q2FT8PZS 23517479 Raffa, RB; Beckett, JR; Brahmbhatt, VN; Ebinger, TM; Fabian, CA; Nixon, JR; Orlando, ST; Rana, CA; Tejani, AH; Tomazic, RJ Temple University School of Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51195395 CC[C@@H]1CN2CCc3c([nH]c4cccc(OC)c34)[C@@H]2C[C@@H]1\C(=C/OC)C(=O)OC InChI=1S/C23H30N2O4/c1-5-14-12-25-10-9-15-21-18(7-6-8-20(21)28-3)24-22(15)19(25)11-16(14)17(13-27-2)23(26)29-4/h6-8,13-14,16,19,24H,5,9-12H2,1-4H3/b17-13+/t14-,16+,19+/m1/s1 LELBFTMXCIIKKX-QVRQZEMUSA-N 50474152 CHEBI:6956::CHEMBL299031 Mu-type opioid receptor Cavia cutleri 7.2 ChEMBL 10.1021/jm400143z 10.7270/Q2FT8PZS 23517479 Raffa, RB; Beckett, JR; Brahmbhatt, VN; Ebinger, TM; Fabian, CA; Nixon, JR; Orlando, ST; Rana, CA; Tejani, AH; Tomazic, RJ Temple University School of Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50474152 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50474152&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3034396 433941417 C09226 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51203274 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C38H47N5O11/c39-26(17-22-8-12-24(45)13-9-22)37(52)43-16-4-7-29(43)36(51)42-28(35(50)41-27(34(40)49)18-21-5-2-1-3-6-21)19-23-10-14-25(15-11-23)53-38-33(48)32(47)31(46)30(20-44)54-38/h1-3,5-6,8-15,26-33,38,44-48H,4,7,16-20,39H2,(H2,40,49)(H,41,50)(H,42,51)/t26-,27-,28-,29-,30+,31+,32-,33+,38+/m0/s1 QPFQQBYRNVGIAD-NBLQFAQPSA-N 50494714 CHEMBL3093783 Mu-type opioid receptor Cavia cutleri 16 ChEMBL 10.1016/j.bmcl.2013.10.041 10.7270/Q2542RJK 24220171 Fichna, J; Mazur, M; Grzywacz, D; Kamysz, W; Perlikowska, R; Piekielna, J; Sobczak, M; Sałaga, M; Toth, G; Janecka, A; Chen, C; Olczak, J Medical University of Lodz http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50494714 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50494714&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73671283 433961979 C03400 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51203277 CC(=O)OC[C@H]1O[C@@H](Oc2ccc(C[C@H](NC(=O)[C@@H]3CCCN3C(=O)[C@@H](N)Cc3ccc(O)cc3)C(=O)N[C@@H](Cc3ccccc3)C(N)=O)cc2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O InChI=1S/C46H55N5O15/c1-25(52)61-24-38-39(62-26(2)53)40(63-27(3)54)41(64-28(4)55)46(66-38)65-33-18-14-31(15-19-33)23-36(43(58)49-35(42(48)57)22-29-9-6-5-7-10-29)50-44(59)37-11-8-20-51(37)45(60)34(47)21-30-12-16-32(56)17-13-30/h5-7,9-10,12-19,34-41,46,56H,8,11,20-24,47H2,1-4H3,(H2,48,57)(H,49,58)(H,50,59)/t34-,35-,36-,37-,38+,39+,40-,41+,46+/m0/s1 XFUINTRBXGWKEQ-ZTKJLMFUSA-N 50494715 CHEMBL3093784 Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.1016/j.bmcl.2013.10.041 10.7270/Q2542RJK 24220171 Fichna, J; Mazur, M; Grzywacz, D; Kamysz, W; Perlikowska, R; Piekielna, J; Sobczak, M; Sałaga, M; Toth, G; Janecka, A; Chen, C; Olczak, J Medical University of Lodz http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50494715 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50494715&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 76324579 433961980 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51203278 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C32H37N5O5/c33-25(18-23-13-15-24(38)16-14-23)32(42)37-17-7-12-28(37)31(41)36-27(20-22-10-5-2-6-11-22)30(40)35-26(29(34)39)19-21-8-3-1-4-9-21/h1-6,8-11,13-16,25-28,38H,7,12,17-20,33H2,(H2,34,39)(H,35,40)(H,36,41)/t25-,26-,27-,28-/m0/s1 XIJHWXXXIMEHKW-LJWNLINESA-N 50139013 (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::(S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxamide::1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylicacid[1-((S)-(S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL333357::H-Tyr-Pro-Phe-Phe-NH2::Tyr-Pro-Phe-Phe-NH2::endomorphin-2 Mu-type opioid receptor Cavia cutleri 4.7 ChEMBL 10.1016/j.bmcl.2013.10.041 10.7270/Q2542RJK 24220171 Fichna, J; Mazur, M; Grzywacz, D; Kamysz, W; Perlikowska, R; Piekielna, J; Sobczak, M; Sałaga, M; Toth, G; Janecka, A; Chen, C; Olczak, J Medical University of Lodz http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139013&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311081 104029000 CHEMBL333357 3668 ZINC14951634 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51195401 CC[C@@H]1CN2CC[C@@]3(O)C(=Nc4cccc(OC)c34)[C@@H]2C[C@@H]1\C(=C/OC)C(=O)OC InChI=1S/C23H30N2O5/c1-5-14-12-25-10-9-23(27)20-17(7-6-8-19(20)29-3)24-21(23)18(25)11-15(14)16(13-28-2)22(26)30-4/h6-8,13-15,18,27H,5,9-12H2,1-4H3/b16-13+/t14-,15+,18+,23+/m1/s1 RYENLSMHLCNXJT-CYXFISRXSA-N 50474153 CHEMBL61630 Mu-type opioid receptor Cavia cutleri 9.8 ChEMBL 10.1021/jm400143z 10.7270/Q2FT8PZS 23517479 Raffa, RB; Beckett, JR; Brahmbhatt, VN; Ebinger, TM; Fabian, CA; Nixon, JR; Orlando, ST; Rana, CA; Tejani, AH; Tomazic, RJ Temple University School of Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50474153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50474153&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44301524 433941418 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51196565 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(N)=O InChI=1S/C21H25N3O3/c1-12-7-16(25)8-13(2)17(12)10-18(22)21(27)24-11-15-6-4-3-5-14(15)9-19(24)20(23)26/h3-8,18-19,25H,9-11,22H2,1-2H3,(H2,23,26)/t18-,19-/m0/s1 RXAGYENDHOXBOY-OALUTQOASA-N 86664 H-Dmt-Tic-NH2 Mu-type opioid receptor Cavia cutleri >10000 ChEMBL 10.1021/ml400115n 10.7270/Q2CN76VX 24648867 Lee, YS; Qu, HC; Davis, P; Ma, SW; Vardanyan, R; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86664 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86664&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10090388 136352713 ZINC13472294 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51196566 CCC(=O)N(C1CCN(CC1)C(=O)[C@H](Cc1ccc(F)cc1)NC(=O)[C@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)c1ccccc1 InChI=1S/C44H50FN5O5/c1-4-41(52)50(34-12-6-5-7-13-34)35-18-20-48(21-19-35)44(55)39(24-30-14-16-33(45)17-15-30)47-42(53)40-25-31-10-8-9-11-32(31)27-49(40)43(54)38(46)26-37-28(2)22-36(51)23-29(37)3/h5-17,22-23,35,38-40,51H,4,18-21,24-27,46H2,1-3H3,(H,47,53)/t38-,39-,40+/m0/s1 IYBGKVVLPOWJSK-XUTHUYCTSA-N 50492532 CHEMBL2408016 Mu-type opioid receptor Cavia cutleri 720 ChEMBL 10.1021/ml400115n 10.7270/Q2CN76VX 24648867 Lee, YS; Qu, HC; Davis, P; Ma, SW; Vardanyan, R; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492532 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492532&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73350639 433959797 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51196567 CCC(=O)N(C1CCN(CC1)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)c1ccccc1 InChI=1S/C44H51N5O5/c1-4-41(51)49(34-17-9-6-10-18-34)35-19-21-47(22-20-35)44(54)39(25-31-13-7-5-8-14-31)46-42(52)40-26-32-15-11-12-16-33(32)28-48(40)43(53)38(45)27-37-29(2)23-36(50)24-30(37)3/h5-18,23-24,35,38-40,50H,4,19-22,25-28,45H2,1-3H3,(H,46,52)/t38-,39-,40-/m0/s1 KMKSKJSSXJJATB-MXVPUGLGSA-N 50492533 CHEMBL2408011 Mu-type opioid receptor Cavia cutleri 740 ChEMBL 10.1021/ml400115n 10.7270/Q2CN76VX 24648867 Lee, YS; Qu, HC; Davis, P; Ma, SW; Vardanyan, R; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492533 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492533&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73353598 433959798 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51196599 CCC(=O)N(C1CCN(CC1)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)c1ccccc1 InChI=1S/C44H51N5O5/c1-4-41(51)49(34-17-9-6-10-18-34)35-19-21-47(22-20-35)44(54)39(25-31-13-7-5-8-14-31)46-42(52)40-26-32-15-11-12-16-33(32)28-48(40)43(53)38(45)27-37-29(2)23-36(50)24-30(37)3/h5-18,23-24,35,38-40,50H,4,19-22,25-28,45H2,1-3H3,(H,46,52)/t38-,39-,40+/m0/s1 KMKSKJSSXJJATB-XUTHUYCTSA-N 50492534 CHEMBL2408014 Mu-type opioid receptor Cavia cutleri 82 ChEMBL 10.1021/ml400115n 10.7270/Q2CN76VX 24648867 Lee, YS; Qu, HC; Davis, P; Ma, SW; Vardanyan, R; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492534&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73355099 433959799 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51196607 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C39H43N5O5/c1-24-17-30(45)18-25(2)31(24)22-32(40)39(49)44-23-29-16-10-9-15-28(29)21-35(44)38(48)43-34(20-27-13-7-4-8-14-27)37(47)42-33(36(41)46)19-26-11-5-3-6-12-26/h3-18,32-35,45H,19-23,40H2,1-2H3,(H2,41,46)(H,42,47)(H,43,48)/t32-,33-,34-,35-/m0/s1 KYXSQGDWDGTJNF-BBACVFHCSA-N 50001157 CHEMBL538700 Mu-type opioid receptor Cavia cutleri 18 ChEMBL 10.1021/ml400115n 10.7270/Q2CN76VX 24648867 Lee, YS; Qu, HC; Davis, P; Ma, SW; Vardanyan, R; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001157 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001157&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 45272750 242055909 CHEMBL538700 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51196615 CCC(=O)N(C1CCN(CC1)C(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)c1ccccc1 InChI=1S/C44H50ClN5O5/c1-4-41(52)50(34-12-6-5-7-13-34)35-18-20-48(21-19-35)44(55)39(24-30-14-16-33(45)17-15-30)47-42(53)40-25-31-10-8-9-11-32(31)27-49(40)43(54)38(46)26-37-28(2)22-36(51)23-29(37)3/h5-17,22-23,35,38-40,51H,4,18-21,24-27,46H2,1-3H3,(H,47,53)/t38-,39-,40-/m0/s1 UAOWACOVBZWCJS-MXVPUGLGSA-N 50492538 CHEMBL2408012 Mu-type opioid receptor Cavia cutleri 350 ChEMBL 10.1021/ml400115n 10.7270/Q2CN76VX 24648867 Lee, YS; Qu, HC; Davis, P; Ma, SW; Vardanyan, R; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492538 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492538&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71762505 433959803 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51194667 CC[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 InChI=1S/C51H66N8O7/c1-4-43(56-48(63)42(52)31-38-20-22-41(60)23-21-38)49(64)53-33-46(61)55-45(32-37-16-10-6-11-17-37)51(66)57-44(30-35(2)3)50(65)54-34-47(62)59(39-18-12-7-13-19-39)40-25-28-58(29-26-40)27-24-36-14-8-5-9-15-36/h5-23,35,40,42-45,60H,4,24-34,52H2,1-3H3,(H,53,64)(H,54,65)(H,55,61)(H,56,63)(H,57,66)/t42-,43+,44-,45-/m0/s1 QABZKUPOTSMQRW-CSYVQODNSA-N 50491852 CHEMBL2387339 Mu-type opioid receptor Cavia cutleri 97 ChEMBL 10.1016/j.bmcl.2013.03.065 10.7270/Q2T72MCM 23623418 Petrov, RR; Lee, YS; Vardanyan, RS; Liu, L; Ma, SW; Davis, P; Lai, J; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50491852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50491852&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73354966 433959117 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51194675 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C75H126N24O15/c1-7-45(6)61(70(111)94-53(25-17-35-87-75(83)84)71(112)99-36-18-26-58(99)69(110)93-50(21-11-13-31-76)64(105)96-56(38-44(4)5)67(108)95-54(72(113)114)22-12-14-32-77)98-65(106)52(24-16-34-86-74(81)82)91-63(104)51(23-15-33-85-73(79)80)92-66(107)55(37-43(2)3)97-68(109)57(40-46-19-9-8-10-20-46)90-60(102)42-88-59(101)41-89-62(103)49(78)39-47-27-29-48(100)30-28-47/h8-10,19-20,27-30,43-45,49-58,61,100H,7,11-18,21-26,31-42,76-78H2,1-6H3,(H,88,101)(H,89,103)(H,90,102)(H,91,104)(H,92,107)(H,93,110)(H,94,111)(H,95,108)(H,96,105)(H,97,109)(H,98,106)(H,113,114)(H4,79,80,85)(H4,81,82,86)(H4,83,84,87)/t45-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,61-/m0/s1 OVVIBUHLQIYUEU-IWIISZHXSA-N 214798 Dynorphin A (1-17)::YGGFLRRIRPKLK Mu-type opioid receptor Cavia cutleri 1.2 ChEMBL 10.1016/j.bmcl.2013.03.065 10.7270/Q2T72MCM 23623418 Petrov, RR; Lee, YS; Vardanyan, RS; Liu, L; Ma, SW; Davis, P; Lai, J; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=214798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=214798&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 25075996 329965675 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51194676 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C38H54N8O10/c1-20(2)31(37(55)41-19-29(40)48)46-38(56)32(21(3)4)45-35(53)27(15-16-30(49)50)43-36(54)28(18-23-9-7-6-8-10-23)44-33(51)22(5)42-34(52)26(39)17-24-11-13-25(47)14-12-24/h6-14,20-22,26-28,31-32,47H,15-19,39H2,1-5H3,(H2,40,48)(H,41,55)(H,42,52)(H,43,54)(H,44,51)(H,45,53)(H,46,56)(H,49,50)/t22-,26+,27+,28+,31+,32+/m1/s1 NUNBRHVOPFWRRG-RCEFDBTISA-N 50000507 (R)-2-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionylamino]-5-guanidino-pentanoic acid [(S)-1-(2-carbamoyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::(S)-4-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-4-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propylcarbamoyl}-butyric acid::(S)-5-((S)-1-((S)-1-(2-amino-2-oxoethylamino)-3-methyl-1-oxobutan-2-ylamino)-3-methyl-1-oxobutan-2-ylamino)-4-((S)-2-((R)-2-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)propanamido)-3-phenylpropanamido)-5-oxopentanoic acid::4-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-4-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propylcarbamoyl}-butyric acid::4-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-4-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propylcarbamoyl}-butyric acid (deltorphin B)::CHEMBL20226::DELTORPHIN-II::Tyr-D-Ala-Phe-Glu-Val-Val-Gly-NH2::Tyr-D-Ala-Phe-Glu-Val-Val-GlyNH2 Mu-type opioid receptor Cavia cutleri >3000 ChEMBL 10.1016/j.bmcl.2013.03.065 10.7270/Q2T72MCM 23623418 Petrov, RR; Lee, YS; Vardanyan, RS; Liu, L; Ma, SW; Davis, P; Lai, J; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000507 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000507&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10033203 103915055 CHEMBL20226 C18095 ZINC95628075 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51194677 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C46H56N10O10/c1-27(51-43(63)35(47)21-31-13-17-33(57)18-14-31)41(61)49-25-39(59)53-37(23-29-9-5-3-6-10-29)45(65)55-56-46(66)38(24-30-11-7-4-8-12-30)54-40(60)26-50-42(62)28(2)52-44(64)36(48)22-32-15-19-34(58)20-16-32/h3-20,27-28,35-38,57-58H,21-26,47-48H2,1-2H3,(H,49,61)(H,50,62)(H,51,63)(H,52,64)(H,53,59)(H,54,60)(H,55,65)(H,56,66)/t27-,28-,35+,36+,37+,38+/m1/s1 DESSEGDLRYOPTJ-VRANXALZSA-N 21014 (2S)-2-amino-N-[(1R)-1-[({[(1S)-1-{N'-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanoyl]hydrazinecarbonyl}-2-phenylethyl]carbamoyl}methyl)carbamoyl]ethyl]-3-(4-hydroxyphenyl)propanamide::(Tyr-Ala-Gly-Phe-NH2)2::Biphalin::CHEMBL200199::bis(Tyr-Ala-Gly-PheNH2)hydrazide::enkephalin dimer Mu-type opioid receptor Cavia cutleri 8.8 ChEMBL 10.1016/j.bmcl.2013.03.065 10.7270/Q2T72MCM 23623418 Petrov, RR; Lee, YS; Vardanyan, RS; Liu, L; Ma, SW; Davis, P; Lai, J; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21014&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5487663 49689087 CHEMBL200199 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51194678 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccc(Cl)cc1)C(=O)N[C@@H](CCC(=O)NCCCCCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1)C(=O)N[C@@H](Cc1ccc(F)cc1)C(N)=O InChI=1S/C73H85ClFN11O9/c74-53-27-21-50(22-28-53)45-63(82-71(93)64(46-52-47-79-60-18-10-9-17-58(52)60)83-72(94)65-19-12-39-85(65)73(95)59(76)43-49-25-31-57(87)32-26-49)70(92)80-61(69(91)81-62(68(77)90)44-51-23-29-54(75)30-24-51)33-34-66(88)78-38-11-3-8-20-67(89)86(55-15-6-2-7-16-55)56-36-41-84(42-37-56)40-35-48-13-4-1-5-14-48/h1-2,4-7,9-10,13-18,21-32,47,56,59,61-65,79,87H,3,8,11-12,19-20,33-46,76H2,(H2,77,90)(H,78,88)(H,80,92)(H,81,91)(H,82,93)(H,83,94)/t59-,61-,62-,63-,64-,65-/m0/s1 UBIDQBXUAQEXHG-QXDQPINWSA-N 50491859 CHEMBL2387330 Mu-type opioid receptor Cavia cutleri 480 ChEMBL 10.1016/j.bmcl.2013.03.065 10.7270/Q2T72MCM 23623418 Petrov, RR; Lee, YS; Vardanyan, RS; Liu, L; Ma, SW; Davis, P; Lai, J; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50491859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50491859&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71624167 433959124 C03636 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51194679 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)NCCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1)C(=O)N[C@@H](C(C)C)C(N)=O InChI=1S/C101H143N27O15/c1-62(2)55-80(123-95(140)81(57-66-27-12-7-13-28-66)118-84(130)61-116-88(133)64(5)117-89(134)74(102)56-68-39-41-72(129)42-40-68)94(139)121-77(36-22-48-110-98(104)105)90(135)119-78(37-23-49-111-99(106)107)91(136)124-82(58-67-29-14-8-15-30-67)96(141)122-79(38-24-50-112-100(108)109)92(137)125-83(59-69-60-115-75-34-19-18-33-73(69)75)97(142)120-76(93(138)126-86(63(3)4)87(103)132)35-20-21-47-113-101(143)114-51-43-85(131)128(70-31-16-9-17-32-70)71-45-53-127(54-46-71)52-44-65-25-10-6-11-26-65/h6-19,25-34,39-42,60,62-64,71,74,76-83,86,115,129H,20-24,35-38,43-59,61,102H2,1-5H3,(H2,103,132)(H,116,133)(H,117,134)(H,118,130)(H,119,135)(H,120,142)(H,121,139)(H,122,141)(H,123,140)(H,124,136)(H,125,137)(H,126,138)(H4,104,105,110)(H4,106,107,111)(H4,108,109,112)(H2,113,114,143)/t64-,74+,76+,77+,78+,79+,80+,81+,82-,83+,86+/m1/s1 XTEZWFLMGFMXTK-QBJQTMLLSA-N 50491855 CHEMBL2387216 Mu-type opioid receptor Cavia cutleri 7.7 ChEMBL 10.1016/j.bmcl.2013.03.065 10.7270/Q2T72MCM 23623418 Petrov, RR; Lee, YS; Vardanyan, RS; Liu, L; Ma, SW; Davis, P; Lai, J; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50491855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50491855&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71625833 433959120 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51194680 CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCNC(=O)NCCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1)C(O)=O InChI=1S/C86H122ClN21O15/c1-52(2)45-69(105-81(119)70(49-58-28-30-59(87)31-29-58)100-73(111)51-98-75(113)55(5)99-76(114)64(88)50-63-53(3)46-62(109)47-54(63)4)80(118)102-66(27-18-40-95-85(92)93)77(115)101-65(26-17-39-94-84(90)91)78(116)103-67(32-33-72(89)110)79(117)106-71(48-57-21-11-7-12-22-57)82(120)104-68(83(121)122)25-15-16-38-96-86(123)97-41-34-74(112)108(60-23-13-8-14-24-60)61-36-43-107(44-37-61)42-35-56-19-9-6-10-20-56/h6-14,19-24,28-31,46-47,52,55,61,64-71,109H,15-18,25-27,32-45,48-51,88H2,1-5H3,(H2,89,110)(H,98,113)(H,99,114)(H,100,111)(H,101,115)(H,102,118)(H,103,116)(H,104,120)(H,105,119)(H,106,117)(H,121,122)(H4,90,91,94)(H4,92,93,95)(H2,96,97,123)/t55-,64+,65-,66+,67+,68+,69+,70+,71+/m1/s1 PLUMIBDAPFTPHI-DDDCEGLSSA-N 50491860 CHEMBL2387215 Mu-type opioid receptor Cavia cutleri 3.8 ChEMBL 10.1016/j.bmcl.2013.03.065 10.7270/Q2T72MCM 23623418 Petrov, RR; Lee, YS; Vardanyan, RS; Liu, L; Ma, SW; Davis, P; Lai, J; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50491860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50491860&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71625832 433959125 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51194681 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 InChI=1S/C50H64N8O7/c1-34(2)29-43(49(64)53-33-46(61)58(39-17-11-6-12-18-39)40-24-27-57(28-25-40)26-23-36-13-7-4-8-14-36)56-50(65)44(31-37-15-9-5-10-16-37)55-45(60)32-52-47(62)35(3)54-48(63)42(51)30-38-19-21-41(59)22-20-38/h4-22,34-35,40,42-44,59H,23-33,51H2,1-3H3,(H,52,62)(H,53,64)(H,54,63)(H,55,60)(H,56,65)/t35-,42+,43+,44+/m1/s1 FSWZYRBMNOBTEJ-HIUUOTSJSA-N 50491861 CHEMBL2387341 Mu-type opioid receptor Cavia cutleri 86 ChEMBL 10.1016/j.bmcl.2013.03.065 10.7270/Q2T72MCM 23623418 Petrov, RR; Lee, YS; Vardanyan, RS; Liu, L; Ma, SW; Davis, P; Lai, J; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50491861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50491861&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71625601 433959126 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51194682 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 InChI=1S/C49H62N8O7/c1-34(2)28-42(48(63)53-33-46(61)57(38-16-10-5-11-17-38)39-23-26-56(27-24-39)25-22-35-12-6-3-7-13-35)55-49(64)43(30-36-14-8-4-9-15-36)54-45(60)32-51-44(59)31-52-47(62)41(50)29-37-18-20-40(58)21-19-37/h3-21,34,39,41-43,58H,22-33,50H2,1-2H3,(H,51,59)(H,52,62)(H,53,63)(H,54,60)(H,55,64)/t41-,42-,43-/m0/s1 WRWJIXPKEOGFRL-SVWSIEHRSA-N 50491858 CHEMBL2387338 Mu-type opioid receptor Cavia cutleri 950 ChEMBL 10.1016/j.bmcl.2013.03.065 10.7270/Q2T72MCM 23623418 Petrov, RR; Lee, YS; Vardanyan, RS; Liu, L; Ma, SW; Davis, P; Lai, J; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50491858 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50491858&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71625485 433959123 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51194683 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 InChI=1S/C45H55N7O6/c1-32(49-44(57)39(46)29-35-17-19-38(53)20-18-35)43(56)48-31-41(54)50-40(30-34-13-7-3-8-14-34)45(58)47-25-21-42(55)52(36-15-9-4-10-16-36)37-23-27-51(28-24-37)26-22-33-11-5-2-6-12-33/h2-20,32,37,39-40,53H,21-31,46H2,1H3,(H,47,58)(H,48,56)(H,49,57)(H,50,54)/t32-,39+,40+/m1/s1 WTPXLBTVBOBEDI-JURIQKAMSA-N 50191056 (S)-2-amino-3-(4-hydroxy-phenyl)-N-((R)-1-{[((S)-1-{2-[(1-phenethyl-piperidin-4-yl)-phenyl-carbamoyl]-ethylcarbamoyl}-2-phenyl-ethylcarbamoyl)-methyl]-carbamoyl}-ethyl)-propionamide::CHEMBL214022 Mu-type opioid receptor Cavia cutleri 110 ChEMBL 10.1016/j.bmcl.2013.03.065 10.7270/Q2T72MCM 23623418 Petrov, RR; Lee, YS; Vardanyan, RS; Liu, L; Ma, SW; Davis, P; Lai, J; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50191056 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50191056&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16046123 104074222 CHEMBL214022 ZINC95542936 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51194684 O=C(CCNC(=O)c1ccccc1)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 InChI=1S/C29H33N3O2/c33-28(16-20-30-29(34)25-12-6-2-7-13-25)32(26-14-8-3-9-15-26)27-18-22-31(23-19-27)21-17-24-10-4-1-5-11-24/h1-15,27H,16-23H2,(H,30,34) HPHFJEIBAYXGJV-UHFFFAOYSA-N 50491862 CHEMBL2387336 Mu-type opioid receptor Cavia cutleri 3900 ChEMBL 10.1016/j.bmcl.2013.03.065 10.7270/Q2T72MCM 23623418 Petrov, RR; Lee, YS; Vardanyan, RS; Liu, L; Ma, SW; Davis, P; Lai, J; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50491862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50491862&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73345882 433959127 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51194685 CC(=O)NCCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 InChI=1S/C24H31N3O2/c1-20(28)25-16-12-24(29)27(22-10-6-3-7-11-22)23-14-18-26(19-15-23)17-13-21-8-4-2-5-9-21/h2-11,23H,12-19H2,1H3,(H,25,28) BDDHGMFOOKYNHZ-UHFFFAOYSA-N 50191060 3-acetamido-N-(1-phenethylpiperidin-4-yl)-N-phenylpropanamide::CHEMBL386990 Mu-type opioid receptor Cavia cutleri 5200 ChEMBL 10.1016/j.bmcl.2013.03.065 10.7270/Q2T72MCM 23623418 Petrov, RR; Lee, YS; Vardanyan, RS; Liu, L; Ma, SW; Davis, P; Lai, J; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50191060 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50191060&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44416410 104074226 CHEMBL386990 ZINC36216368 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51194686 Cl.O=C(CN1C(=O)c2ccccc2C1=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 InChI=1S/C29H29N3O3/c33-27(21-31-28(34)25-13-7-8-14-26(25)29(31)35)32(23-11-5-2-6-12-23)24-16-19-30(20-17-24)18-15-22-9-3-1-4-10-22/h1-14,24H,15-21H2 TZHRPPAWFBZUEC-UHFFFAOYSA-N 50491863 CHEMBL2387335 Mu-type opioid receptor Cavia cutleri 5900 ChEMBL 10.1016/j.bmcl.2013.03.065 10.7270/Q2T72MCM 23623418 Petrov, RR; Lee, YS; Vardanyan, RS; Liu, L; Ma, SW; Davis, P; Lai, J; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50491863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50491863&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71624412 433959128 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51194698 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)NCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 InChI=1S/C46H56N8O7/c1-32(51-45(60)39(47)27-35-17-19-38(55)20-18-35)44(59)49-30-42(57)52-40(28-34-13-7-3-8-14-34)46(61)50-29-41(56)48-31-43(58)54(36-15-9-4-10-16-36)37-22-25-53(26-23-37)24-21-33-11-5-2-6-12-33/h2-20,32,37,39-40,55H,21-31,47H2,1H3,(H,48,56)(H,49,59)(H,50,61)(H,51,60)(H,52,57)/t32-,39+,40+/m1/s1 ZXXWQHJJTYRVST-JURIQKAMSA-N 50491867 CHEMBL2387210 Mu-type opioid receptor Cavia cutleri 150 ChEMBL 10.1016/j.bmcl.2013.03.065 10.7270/Q2T72MCM 23623418 Petrov, RR; Lee, YS; Vardanyan, RS; Liu, L; Ma, SW; Davis, P; Lai, J; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50491867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50491867&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73354965 433959132 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51194735 CC(C)C[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCNC(=O)NCCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1)C(O)=O InChI=1S/C64H90N14O11/c1-42(2)38-53(76-61(86)54(40-45-18-9-5-10-19-45)73-55(80)41-71-57(82)43(3)72-58(83)50(65)39-46-24-26-49(79)27-25-46)60(85)74-51(23-15-33-68-63(66)67)59(84)75-52(62(87)88)22-13-14-32-69-64(89)70-34-28-56(81)78(47-20-11-6-12-21-47)48-30-36-77(37-31-48)35-29-44-16-7-4-8-17-44/h4-12,16-21,24-27,42-43,48,50-54,79H,13-15,22-23,28-41,65H2,1-3H3,(H,71,82)(H,72,83)(H,73,80)(H,74,85)(H,75,84)(H,76,86)(H,87,88)(H4,66,67,68)(H2,69,70,89)/t43-,50+,51+,52+,53-,54+/m1/s1 HKYFTGIURHUTRW-LGXZQHJQSA-N 50491857 CHEMBL2387213 Mu-type opioid receptor Cavia cutleri 98 ChEMBL 10.1016/j.bmcl.2013.03.065 10.7270/Q2T72MCM 23623418 Petrov, RR; Lee, YS; Vardanyan, RS; Liu, L; Ma, SW; Davis, P; Lai, J; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50491857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50491857&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71625714 433959122 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51194744 CC(C)C[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCNC(=O)NCCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1)C(O)=O InChI=1S/C75H100N16O12/c1-48(2)42-62(88-71(99)63(44-51-20-9-5-10-21-51)85-65(93)47-83-67(95)49(3)84-68(96)58(76)43-52-28-30-56(92)31-29-52)70(98)86-60(27-17-37-79-74(77)78)69(97)89-64(45-53-46-82-59-25-14-13-24-57(53)59)72(100)87-61(73(101)102)26-15-16-36-80-75(103)81-38-32-66(94)91(54-22-11-6-12-23-54)55-34-40-90(41-35-55)39-33-50-18-7-4-8-19-50/h4-14,18-25,28-31,46,48-49,55,58,60-64,82,92H,15-17,26-27,32-45,47,76H2,1-3H3,(H,83,95)(H,84,96)(H,85,93)(H,86,98)(H,87,100)(H,88,99)(H,89,97)(H,101,102)(H4,77,78,79)(H2,80,81,103)/t49-,58-,60-,61-,62+,63-,64-/m0/s1 BDZOQFBBMRXVPH-PRJVLWKRSA-N 50491856 CHEMBL2387214 Mu-type opioid receptor Cavia cutleri 120 ChEMBL 10.1016/j.bmcl.2013.03.065 10.7270/Q2T72MCM 23623418 Petrov, RR; Lee, YS; Vardanyan, RS; Liu, L; Ma, SW; Davis, P; Lai, J; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50491856 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50491856&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73351999 433959121 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51194745 CCNC(=O)NCCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 InChI=1S/C25H34N4O2/c1-2-26-25(31)27-17-13-24(30)29(22-11-7-4-8-12-22)23-15-19-28(20-16-23)18-14-21-9-5-3-6-10-21/h3-12,23H,2,13-20H2,1H3,(H2,26,27,31) JFWGDNMHRRUUTG-UHFFFAOYSA-N 50191053 1-ethyl-3-(3-oxo-3-((1-phenethylpiperidin-4-yl)(phenyl)amino)propyl)urea::CHEMBL385909 Mu-type opioid receptor Cavia cutleri 1300 ChEMBL 10.1016/j.bmcl.2013.03.065 10.7270/Q2T72MCM 23623418 Petrov, RR; Lee, YS; Vardanyan, RS; Liu, L; Ma, SW; Davis, P; Lai, J; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50191053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50191053&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44416659 104074219 CHEMBL385909 ZINC36216365 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51194749 CC(C)C[C@H](NC(=O)[C@H](CCC(=O)NCCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(N)=O InChI=1S/C64H88ClN11O10/c1-39(2)32-53(59(67)81)73-62(84)52(22-23-56(78)68-28-24-58(80)76(47-16-12-9-13-17-47)48-26-30-75(31-27-48)29-25-44-14-10-8-11-15-44)72-63(85)54(33-40(3)4)74-64(86)55(36-45-18-20-46(65)21-19-45)71-57(79)38-69-60(82)43(7)70-61(83)51(66)37-50-41(5)34-49(77)35-42(50)6/h8-21,34-35,39-40,43,48,51-55,77H,22-33,36-38,66H2,1-7H3,(H2,67,81)(H,68,78)(H,69,82)(H,70,83)(H,71,79)(H,72,85)(H,73,84)(H,74,86)/t43-,51+,52+,53+,54-,55+/m1/s1 QOAOLJDIUMCTMF-FTNIFCOMSA-N 50491854 CHEMBL2387327 Mu-type opioid receptor Cavia cutleri 12 ChEMBL 10.1016/j.bmcl.2013.03.065 10.7270/Q2T72MCM 23623418 Petrov, RR; Lee, YS; Vardanyan, RS; Liu, L; Ma, SW; Davis, P; Lai, J; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50491854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50491854&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71625948 433959119 C03636 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51194755 CCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 InChI=1S/C22H28N2O/c1-2-22(25)24(20-11-7-4-8-12-20)21-14-17-23(18-15-21)16-13-19-9-5-3-6-10-19/h3-12,21H,2,13-18H2,1H3 PJMPHNIQZUBGLI-UHFFFAOYSA-N 50008984 4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-phthalazin-1-one::CHEMBL596::Duragesic-100::Duragesic-12::Duragesic-25::Duragesic-50::Duragesic-75::FENTANYL::FENTANYL CITRATE::FENTANYL-HCl::Fentanyl-100::Fentanyl-12::Fentanyl-25::Fentanyl-50::Fentanyl-75::Fentora::Innovar::Ionsys::N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide::N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide(Fentanyl)::N-(1-phenethylpiperidin-4-yl)-N-phenylpropionamide Mu-type opioid receptor Cavia cutleri 3.4 ChEMBL 10.1016/j.bmcl.2013.03.065 10.7270/Q2T72MCM 23623418 Petrov, RR; Lee, YS; Vardanyan, RS; Liu, L; Ma, SW; Davis, P; Lai, J; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008984&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 7V7 5TZO,8EF5,7U64 3345 103922051 119915 CHEMBL596 DB00813 1626 ZINC02522669 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51194756 CC(C)[C@H](NC(=O)[C@@H](NC(=O)C(C)(C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)N[C@@H](CCC(=O)NCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1)C(N)=O InChI=1S/C61H83N11O10/c1-38(2)52(58(80)66-48(54(63)76)27-28-50(74)64-37-51(75)72(44-21-15-10-16-22-44)45-30-33-71(34-31-45)32-29-41-17-11-8-12-18-41)68-59(81)53(39(3)4)69-60(82)61(6,7)70-57(79)49(36-42-19-13-9-14-20-42)67-55(77)40(5)65-56(78)47(62)35-43-23-25-46(73)26-24-43/h8-26,38-40,45,47-49,52-53,73H,27-37,62H2,1-7H3,(H2,63,76)(H,64,74)(H,65,78)(H,66,80)(H,67,77)(H,68,81)(H,69,82)(H,70,79)/t40-,47+,48+,49+,52+,53+/m1/s1 OOOQPXIKDXSCRA-BVWCKYCNSA-N 50491865 CHEMBL2387211 Mu-type opioid receptor Cavia cutleri 49 ChEMBL 10.1016/j.bmcl.2013.03.065 10.7270/Q2T72MCM 23623418 Petrov, RR; Lee, YS; Vardanyan, RS; Liu, L; Ma, SW; Davis, P; Lai, J; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50491865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50491865&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71624288 433959130 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51194779 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)NCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1)C(N)=O InChI=1S/C60H70N10O8/c61-48(35-42-22-24-46(71)25-23-42)60(78)69-31-12-21-53(69)59(77)67-52(37-43-38-63-49-20-11-10-19-47(43)49)58(76)66-51(36-41-15-6-2-7-16-41)57(75)65-50(56(62)74)26-27-54(72)64-39-55(73)70(44-17-8-3-9-18-44)45-29-33-68(34-30-45)32-28-40-13-4-1-5-14-40/h1-11,13-20,22-25,38,45,48,50-53,63,71H,12,21,26-37,39,61H2,(H2,62,74)(H,64,72)(H,65,75)(H,66,76)(H,67,77)/t48-,50-,51-,52-,53-/m0/s1 OXWUDPZQSYWZFQ-HDUUNEDUSA-N 50491868 CHEMBL2387331 Mu-type opioid receptor Cavia cutleri 2100 ChEMBL 10.1016/j.bmcl.2013.03.065 10.7270/Q2T72MCM 23623418 Petrov, RR; Lee, YS; Vardanyan, RS; Liu, L; Ma, SW; Davis, P; Lai, J; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50491868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50491868&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71624287 433959133 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51194780 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(Cl)cc1)C(=O)N[C@@H](CCC(=O)NCCCCCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1)C(=O)N[C@@H](Cc1c(F)c(F)c(F)c(F)c1F)C(N)=O InChI=1S/C62H72ClF5N10O9/c1-37(73-60(85)46(69)33-39-18-22-44(79)23-19-39)59(84)72-36-51(81)74-49(34-40-16-20-41(63)21-17-40)62(87)75-47(61(86)76-48(58(70)83)35-45-53(64)55(66)57(68)56(67)54(45)65)24-25-50(80)71-29-10-4-9-15-52(82)78(42-13-7-3-8-14-42)43-27-31-77(32-28-43)30-26-38-11-5-2-6-12-38/h2-3,5-8,11-14,16-23,37,43,46-49,79H,4,9-10,15,24-36,69H2,1H3,(H2,70,83)(H,71,80)(H,72,84)(H,73,85)(H,74,81)(H,75,87)(H,76,86)/t37-,46+,47+,48+,49+/m1/s1 INQWRMKPKQZIOZ-HOZBKMJVSA-N 50491869 CHEMBL2387328 Mu-type opioid receptor Cavia cutleri 67 ChEMBL 10.1016/j.bmcl.2013.03.065 10.7270/Q2T72MCM 23623418 Petrov, RR; Lee, YS; Vardanyan, RS; Liu, L; Ma, SW; Davis, P; Lai, J; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50491869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50491869&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71625949 433959134 C03636 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51194781 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 InChI=1S/C52H66N8O7/c1-36(2)31-44(49(64)55-35-48(63)60(40-17-10-5-11-18-40)41-25-29-58(30-26-41)28-24-37-13-6-3-7-14-37)57-50(65)45(33-38-15-8-4-9-16-38)56-47(62)34-54-51(66)46-19-12-27-59(46)52(67)43(53)32-39-20-22-42(61)23-21-39/h3-11,13-18,20-23,36,41,43-46,61H,12,19,24-35,53H2,1-2H3,(H,54,66)(H,55,64)(H,56,62)(H,57,65)/t43-,44-,45-,46+/m0/s1 MAQUSQDHEVVQSF-QVXITYKDSA-N 50491866 CHEMBL2387340 Mu-type opioid receptor Cavia cutleri 580 ChEMBL 10.1016/j.bmcl.2013.03.065 10.7270/Q2T72MCM 23623418 Petrov, RR; Lee, YS; Vardanyan, RS; Liu, L; Ma, SW; Davis, P; Lai, J; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50491866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50491866&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71625600 433959131 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51194782 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 InChI=1S/C45H55N7O6/c1-32(49-44(57)39(46)29-35-17-19-38(53)20-18-35)43(56)48-31-41(54)50-40(30-34-13-7-3-8-14-34)45(58)47-25-21-42(55)52(36-15-9-4-10-16-36)37-23-27-51(28-24-37)26-22-33-11-5-2-6-12-33/h2-20,32,37,39-40,53H,21-31,46H2,1H3,(H,47,58)(H,48,56)(H,49,57)(H,50,54)/t32-,39+,40+/m1/s1 WTPXLBTVBOBEDI-JURIQKAMSA-N 50191056 (S)-2-amino-3-(4-hydroxy-phenyl)-N-((R)-1-{[((S)-1-{2-[(1-phenethyl-piperidin-4-yl)-phenyl-carbamoyl]-ethylcarbamoyl}-2-phenyl-ethylcarbamoyl)-methyl]-carbamoyl}-ethyl)-propionamide::CHEMBL214022 Mu-type opioid receptor Cavia cutleri 42 ChEMBL 10.1016/j.bmcl.2013.03.065 10.7270/Q2T72MCM 23623418 Petrov, RR; Lee, YS; Vardanyan, RS; Liu, L; Ma, SW; Davis, P; Lai, J; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50191056 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50191056&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16046123 104074222 CHEMBL214022 ZINC95542936 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51194783 CCC(=O)NCCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 InChI=1S/C25H33N3O2/c1-2-24(29)26-17-13-25(30)28(22-11-7-4-8-12-22)23-15-19-27(20-16-23)18-14-21-9-5-3-6-10-21/h3-12,23H,2,13-20H2,1H3,(H,26,29) WYIBCWLEEYFLPE-UHFFFAOYSA-N 50191058 CHEMBL214285::N-(1-phenethyl-piperidin-4-yl)-N-phenyl-3-propionylamino-propionamide Mu-type opioid receptor Cavia cutleri 1400 ChEMBL 10.1016/j.bmcl.2013.03.065 10.7270/Q2T72MCM 23623418 Petrov, RR; Lee, YS; Vardanyan, RS; Liu, L; Ma, SW; Davis, P; Lai, J; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50191058 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50191058&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44416411 104074224 CHEMBL214285 ZINC36216370 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51194789 FC(F)(F)C(=O)NCCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 InChI=1S/C24H28F3N3O2/c25-24(26,27)23(32)28-15-11-22(31)30(20-9-5-2-6-10-20)21-13-17-29(18-14-21)16-12-19-7-3-1-4-8-19/h1-10,21H,11-18H2,(H,28,32) LBTODCUSAJWMJM-UHFFFAOYSA-N 50191057 CHEMBL214657::N-(1-phenethylpiperidin-4-yl)-N-phenyl-3-(2,2,2-trifluoroacetamido)propanamide Mu-type opioid receptor Cavia cutleri 3000 ChEMBL 10.1016/j.bmcl.2013.03.065 10.7270/Q2T72MCM 23623418 Petrov, RR; Lee, YS; Vardanyan, RS; Liu, L; Ma, SW; Davis, P; Lai, J; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50191057 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50191057&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44416658 104074223 CHEMBL214657 ZINC36216363 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51194792 CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(=O)NCCCCCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1)C(=O)N[C@@H](Cc1c(F)c(F)c(F)c(F)c1F)C(N)=O InChI=1S/C74H96F5N15O11/c1-44(2)39-57(92-73(105)58(41-47-19-10-5-11-20-47)88-60(97)43-86-68(100)45(3)87-69(101)53(80)40-48-25-27-51(95)28-26-48)72(104)89-54(23-16-35-85-74(82)83)70(102)90-55(71(103)91-56(67(81)99)42-52-62(75)64(77)66(79)65(78)63(52)76)29-30-59(96)84-34-15-7-14-24-61(98)94(49-21-12-6-13-22-49)50-32-37-93(38-33-50)36-31-46-17-8-4-9-18-46/h4-6,8-13,17-22,25-28,44-45,50,53-58,95H,7,14-16,23-24,29-43,80H2,1-3H3,(H2,81,99)(H,84,96)(H,86,100)(H,87,101)(H,88,97)(H,89,104)(H,90,102)(H,91,103)(H,92,105)(H4,82,83,85)/t45-,53+,54+,55+,56+,57+,58+/m1/s1 NJBAWVLSMORLFD-NEWXAXLISA-N 50491853 CHEMBL2387329 Mu-type opioid receptor Cavia cutleri 130 ChEMBL 10.1016/j.bmcl.2013.03.065 10.7270/Q2T72MCM 23623418 Petrov, RR; Lee, YS; Vardanyan, RS; Liu, L; Ma, SW; Davis, P; Lai, J; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50491853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50491853&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71624166 433959118 C03636 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51194794 CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)NCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)NCC(N)=O InChI=1S/C59H79N11O10/c1-37(2)52(58(79)63-35-49(61)72)68-59(80)53(38(3)4)67-56(77)47(65-57(78)48(34-41-17-11-7-12-18-41)66-54(75)39(5)64-55(76)46(60)33-42-21-23-45(71)24-22-42)25-26-50(73)62-36-51(74)70(43-19-13-8-14-20-43)44-28-31-69(32-29-44)30-27-40-15-9-6-10-16-40/h6-24,37-39,44,46-48,52-53,71H,25-36,60H2,1-5H3,(H2,61,72)(H,62,73)(H,63,79)(H,64,76)(H,65,78)(H,66,75)(H,67,77)(H,68,80)/t39-,46+,47+,48+,52+,53+/m1/s1 ONBTXPSIQFFZPI-FBYZWIEBSA-N 50491864 CHEMBL2387212 Mu-type opioid receptor Cavia cutleri 1900 ChEMBL 10.1016/j.bmcl.2013.03.065 10.7270/Q2T72MCM 23623418 Petrov, RR; Lee, YS; Vardanyan, RS; Liu, L; Ma, SW; Davis, P; Lai, J; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50491864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50491864&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71624409 433959129 C03636 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51194795 CC(=O)NC(Cc1ccccc1)C(=O)NCCC(=O)N(C1CCN(CCc2ccccc2)CC1)c1ccccc1 InChI=1S/C33H40N4O3/c1-26(38)35-31(25-28-13-7-3-8-14-28)33(40)34-21-17-32(39)37(29-15-9-4-10-16-29)30-19-23-36(24-20-30)22-18-27-11-5-2-6-12-27/h2-16,30-31H,17-25H2,1H3,(H,34,40)(H,35,38) WUNPBVOUZWDDSI-UHFFFAOYSA-N 50191059 2-acetylamino-N-{2-[(1-phenethyl-piperidin-4-yl)-phenyl-carbamoyl]-ethyl}-3-phenyl-propionamide::CHEMBL216492 Mu-type opioid receptor Cavia cutleri 5600 ChEMBL 10.1016/j.bmcl.2013.03.065 10.7270/Q2T72MCM 23623418 Petrov, RR; Lee, YS; Vardanyan, RS; Liu, L; Ma, SW; Davis, P; Lai, J; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50191059 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50191059&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44416676 104074225 CHEMBL216492 ZINC36216376 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51194805 N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C34H38N6O5/c35-26(17-22-12-14-24(41)15-13-22)34(45)40-16-6-11-30(40)33(44)39-29(19-23-20-37-27-10-5-4-9-25(23)27)32(43)38-28(31(36)42)18-21-7-2-1-3-8-21/h1-5,7-10,12-15,20,26,28-30,37,41H,6,11,16-19,35H2,(H2,36,42)(H,38,43)(H,39,44)/t26-,28-,29-,30-/m0/s1 ZEXLJFNSKAHNFH-SYKYGTKKSA-N 50095155 (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide::(S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxamide::1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [1-((S)-(S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide::1-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [1-(1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide::CHEMBL316446::ENDOMORPHIN-1::H-Tyr-Pro-Trp-Phe-NH2::Tyr-Pro-Trp-Phe-NH2::YPWF-NH2::endomorphin -1 Mu-type opioid receptor Cavia cutleri 11 ChEMBL 10.1016/j.bmcl.2013.03.065 10.7270/Q2T72MCM 23623418 Petrov, RR; Lee, YS; Vardanyan, RS; Liu, L; Ma, SW; Davis, P; Lai, J; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095155&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311080 103992914 CHEMBL316446 1623 ZINC14951658 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51198426 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1CN[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C36H48N6O4/c1-23-16-29(43)17-24(2)30(23)20-31(38)36(46)42-22-27-13-7-6-12-26(27)19-28(42)21-40-32(14-8-9-15-37)35(45)41-33(34(39)44)18-25-10-4-3-5-11-25/h3-7,10-13,16-17,28,31-33,40,43H,8-9,14-15,18-22,37-38H2,1-2H3,(H2,39,44)(H,41,45)/t28-,31-,32-,33-/m0/s1 IHZHXWXPFPRICT-XGKFQTDJSA-N 50493139 CHEMBL3038177 Mu-type opioid receptor Cavia cutleri 5.7 ChEMBL 10.1016/j.bmcl.2013.07.036 10.7270/Q2RN3BSK 23932788 Weltrowska, G; Nguyen, TM; Chung, NN; Wilkes, BC; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493139 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493139&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73357333 433960404 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51198427 Cc1cc(O)cc(C)c1C[C@H](NC(N)=N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C37H48N8O5/c1-22-16-27(46)17-23(2)28(22)20-31(44-37(40)41)36(50)45-21-26-13-7-6-12-25(26)19-32(45)35(49)42-29(14-8-9-15-38)34(48)43-30(33(39)47)18-24-10-4-3-5-11-24/h3-7,10-13,16-17,29-32,46H,8-9,14-15,18-21,38H2,1-2H3,(H2,39,47)(H,42,49)(H,43,48)(H4,40,41,44)/t29-,30-,31-,32-/m0/s1 GBLYOVUOLPEFOE-YDPTYEFTSA-N 50493132 CHEMBL3038179 Mu-type opioid receptor Cavia cutleri 0.289000 ChEMBL 10.1016/j.bmcl.2013.07.036 10.7270/Q2RN3BSK 23932788 Weltrowska, G; Nguyen, TM; Chung, NN; Wilkes, BC; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493132&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73354256 433960397 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51198428 Cc1cc(O)cc(C)c1C[C@H](NC(N)=N)C(=O)N1Cc2ccccc2C[C@H]1CN[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C40H47N7O4/c1-25-17-32(48)18-26(2)33(25)22-36(46-40(42)43)39(51)47-24-30-16-10-9-15-29(30)21-31(47)23-44-35(20-28-13-7-4-8-14-28)38(50)45-34(37(41)49)19-27-11-5-3-6-12-27/h3-18,31,34-36,44,48H,19-24H2,1-2H3,(H2,41,49)(H,45,50)(H4,42,43,46)/t31-,34-,35-,36-/m0/s1 HTFGJKCOMNOOSW-SNZVYYTPSA-N 50493133 CHEMBL3038185 Mu-type opioid receptor Cavia cutleri 1.2 ChEMBL 10.1016/j.bmcl.2013.07.036 10.7270/Q2RN3BSK 23932788 Weltrowska, G; Nguyen, TM; Chung, NN; Wilkes, BC; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493133 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493133&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73354258 433960398 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51198429 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C39H43N5O5/c1-24-17-30(45)18-25(2)31(24)22-32(40)39(49)44-23-29-16-10-9-15-28(29)21-35(44)38(48)43-34(20-27-13-7-4-8-14-27)37(47)42-33(36(41)46)19-26-11-5-3-6-12-26/h3-18,32-35,45H,19-23,40H2,1-2H3,(H2,41,46)(H,42,47)(H,43,48)/t32-,33-,34-,35-/m0/s1 KYXSQGDWDGTJNF-BBACVFHCSA-N 50001157 CHEMBL538700 Mu-type opioid receptor Cavia cutleri 18 ChEMBL 10.1016/j.bmcl.2013.07.036 10.7270/Q2RN3BSK 23932788 Weltrowska, G; Nguyen, TM; Chung, NN; Wilkes, BC; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001157 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001157&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 45272750 242055909 CHEMBL538700 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51198436 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1CN[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C39H45N5O4/c1-25-17-32(45)18-26(2)33(25)22-34(40)39(48)44-24-30-16-10-9-15-29(30)21-31(44)23-42-36(20-28-13-7-4-8-14-28)38(47)43-35(37(41)46)19-27-11-5-3-6-12-27/h3-18,31,34-36,42,45H,19-24,40H2,1-2H3,(H2,41,46)(H,43,47)/t31?,34-,35-,36-/m0/s1 MZZBNDGZTPEYGP-QHMGJUIVSA-N 50080453 (S)-2-({2-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinolin-3-ylmethyl}-amino)-N-((S)-1-carbamoyl-2-phenyl-ethyl)-3-phenyl-propionamide::CHEMBL119590 Mu-type opioid receptor Cavia cutleri 7.7 ChEMBL 10.1016/j.bmcl.2013.07.036 10.7270/Q2RN3BSK 23932788 Weltrowska, G; Nguyen, TM; Chung, NN; Wilkes, BC; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080453&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44344690 103980610 CHEMBL119590 ZINC58617670 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51198438 Cc1cc(O)cc(C)c1C[C@H](NC(N)=N)C(=O)N1Cc2ccccc2C[C@H]1CN[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C37H50N8O4/c1-23-16-29(46)17-24(2)30(23)20-33(44-37(40)41)36(49)45-22-27-13-7-6-12-26(27)19-28(45)21-42-31(14-8-9-15-38)35(48)43-32(34(39)47)18-25-10-4-3-5-11-25/h3-7,10-13,16-17,28,31-33,42,46H,8-9,14-15,18-22,38H2,1-2H3,(H2,39,47)(H,43,48)(H4,40,41,44)/t28-,31-,32-,33-/m0/s1 WVMDYLRXHYHUSB-XGKFQTDJSA-N 50493136 CHEMBL3038181 Mu-type opioid receptor Cavia cutleri 9.5 ChEMBL 10.1016/j.bmcl.2013.07.036 10.7270/Q2RN3BSK 23932788 Weltrowska, G; Nguyen, TM; Chung, NN; Wilkes, BC; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493136&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73352753 433960401 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51198453 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C36H46N6O5/c1-22-16-27(43)17-23(2)28(22)20-29(38)36(47)42-21-26-13-7-6-12-25(26)19-32(42)35(46)40-30(14-8-9-15-37)34(45)41-31(33(39)44)18-24-10-4-3-5-11-24/h3-7,10-13,16-17,29-32,43H,8-9,14-15,18-21,37-38H2,1-2H3,(H2,39,44)(H,40,46)(H,41,45)/t29-,30-,31-,32-/m0/s1 CGVRVIAPYFDFJZ-YDPTYEFTSA-N 50493137 CHEMBL3038180 Mu-type opioid receptor Cavia cutleri 17 ChEMBL 10.1016/j.bmcl.2013.07.036 10.7270/Q2RN3BSK 23932788 Weltrowska, G; Nguyen, TM; Chung, NN; Wilkes, BC; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493137 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493137&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73355825 433960402 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51198454 Cc1cc(O)cc(C)c1C[C@H](NC(N)=N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C40H45N7O5/c1-24-17-30(48)18-25(2)31(24)22-34(46-40(42)43)39(52)47-23-29-16-10-9-15-28(29)21-35(47)38(51)45-33(20-27-13-7-4-8-14-27)37(50)44-32(36(41)49)19-26-11-5-3-6-12-26/h3-18,32-35,48H,19-23H2,1-2H3,(H2,41,49)(H,44,50)(H,45,51)(H4,42,43,46)/t32-,33-,34-,35-/m0/s1 IAZFMBPAZYUYAZ-BBACVFHCSA-N 50493134 CHEMBL3038184 Mu-type opioid receptor Cavia cutleri 8.1 ChEMBL 10.1016/j.bmcl.2013.07.036 10.7270/Q2RN3BSK 23932788 Weltrowska, G; Nguyen, TM; Chung, NN; Wilkes, BC; Schiller, PW Clinical Research Institute of Montreal http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493134 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493134&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 73355826 433960399 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51218280 CCC(=O)N(CC1CCCCN1Cc1ccc2[C@@H](CCCc2c1)N(CCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@H](C)C(=O)N[C@@H](Cc1c(C)cc(O)cc1C)C(O)=O)CCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@H](C)C(=O)N[C@@H](Cc1c(C)cc(O)cc1C)C(O)=O)c1ccccc1 InChI=1S/C82H103N11O15/c1-8-76(100)93(60-26-16-11-17-27-60)49-61-28-18-19-34-92(61)48-58-30-31-64-59(41-58)25-20-29-71(64)91(35-32-72(96)87-67(42-56-21-12-9-13-22-56)79(103)83-46-74(98)85-54(6)77(101)89-69(81(105)106)44-65-50(2)37-62(94)38-51(65)3)36-33-73(97)88-68(43-57-23-14-10-15-24-57)80(104)84-47-75(99)86-55(7)78(102)90-70(82(107)108)45-66-52(4)39-63(95)40-53(66)5/h9-17,21-24,26-27,30-31,37-41,54-55,61,67-71,94-95H,8,18-20,25,28-29,32-36,42-49H2,1-7H3,(H,83,103)(H,84,104)(H,85,98)(H,86,99)(H,87,96)(H,88,97)(H,89,101)(H,90,102)(H,105,106)(H,107,108)/t54-,55-,61?,67+,68+,69+,70+,71-/m1/s1 YCDYCYOYJRVOJF-XZIGOUGGSA-N 50500605 CHEMBL3752798 Mu-type opioid receptor Cavia cutleri 2.1 ChEMBL 10.1016/j.bmcl.2015.10.081 10.7270/Q2W66PSM 26611918 Deekonda, S; Cole, J; Sunna, S; Rankin, D; Largent-Milnes, TM; Davis, P; BassiriRad, NM; Lai, J; Vanderah, TW; Porecca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500605 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500605&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 127034992 433912506 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51218285 CCC(=O)N(CC1CCCCN1[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@H](C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)c1ccccc1 InChI=1S/C38H47N5O7/c1-3-35(46)43(29-14-8-5-9-15-29)25-30-16-10-11-21-42(30)33(23-27-12-6-4-7-13-27)37(48)39-24-34(45)40-26(2)36(47)41-32(38(49)50)22-28-17-19-31(44)20-18-28/h4-9,12-15,17-20,26,30,32-33,44H,3,10-11,16,21-25H2,1-2H3,(H,39,48)(H,40,45)(H,41,47)(H,49,50)/t26-,30?,32+,33+/m1/s1 HZHZYPWUASGOMR-NYIWYSSJSA-N 50500606 CHEMBL3752678 Mu-type opioid receptor Cavia cutleri 21 ChEMBL 10.1016/j.bmcl.2015.10.081 10.7270/Q2W66PSM 26611918 Deekonda, S; Cole, J; Sunna, S; Rankin, D; Largent-Milnes, TM; Davis, P; BassiriRad, NM; Lai, J; Vanderah, TW; Porecca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500606 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500606&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 127035664 433912507 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51218310 CCC(=O)N(CC1CCCCN1Cc1ccc2[C@@H](CCCc2c1)NCCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@H](C)C(=O)N[C@@H](Cc1c(C)cc(O)cc1C)C(O)=O)c1ccccc1 InChI=1S/C54H69N7O8/c1-5-51(65)61(41-18-10-7-11-19-41)34-42-20-12-13-26-60(42)33-39-22-23-44-40(29-39)17-14-21-46(44)55-25-24-49(63)58-47(30-38-15-8-6-9-16-38)53(67)56-32-50(64)57-37(4)52(66)59-48(54(68)69)31-45-35(2)27-43(62)28-36(45)3/h6-11,15-16,18-19,22-23,27-29,37,42,46-48,55,62H,5,12-14,17,20-21,24-26,30-34H2,1-4H3,(H,56,67)(H,57,64)(H,58,63)(H,59,66)(H,68,69)/t37-,42?,46-,47+,48+/m1/s1 HMLKHYKRLWJQOG-JKTLKNKKSA-N 50500608 CHEMBL3753711 Mu-type opioid receptor Cavia cutleri 5.7 ChEMBL 10.1016/j.bmcl.2015.10.081 10.7270/Q2W66PSM 26611918 Deekonda, S; Cole, J; Sunna, S; Rankin, D; Largent-Milnes, TM; Davis, P; BassiriRad, NM; Lai, J; Vanderah, TW; Porecca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500608 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500608&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 127037438 433912509 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51218313 CCC(=O)N(CC1CCCCN1Cc1ccc2[C@@H](CCCc2c1)N[C@H](Cc1ccccc1)C(=O)NCC(=O)N[C@H](C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)c1ccccc1 InChI=1S/C49H60N6O7/c1-3-46(58)55(38-16-8-5-9-17-38)32-39-18-10-11-26-54(39)31-36-22-25-41-37(27-36)15-12-19-42(41)52-43(28-34-13-6-4-7-14-34)48(60)50-30-45(57)51-33(2)47(59)53-44(49(61)62)29-35-20-23-40(56)24-21-35/h4-9,13-14,16-17,20-25,27,33,39,42-44,52,56H,3,10-12,15,18-19,26,28-32H2,1-2H3,(H,50,60)(H,51,57)(H,53,59)(H,61,62)/t33-,39?,42-,43-,44+/m1/s1 OHXAATBRYBMJJL-HDPIZSEHSA-N 50500611 CHEMBL4299482 Mu-type opioid receptor Cavia cutleri 95 ChEMBL 10.1016/j.bmcl.2015.10.081 10.7270/Q2W66PSM 26611918 Deekonda, S; Cole, J; Sunna, S; Rankin, D; Largent-Milnes, TM; Davis, P; BassiriRad, NM; Lai, J; Vanderah, TW; Porecca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500611 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500611&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145948980 433912512 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51218314 CCC(=O)N(CC1CCCCN1[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@H](C)C(=O)N[C@@H](Cc1c(C)cc(O)cc1C)C(O)=O)c1ccccc1 InChI=1S/C40H51N5O7/c1-5-37(48)45(30-16-10-7-11-17-30)25-31-18-12-13-19-44(31)35(22-29-14-8-6-9-15-29)39(50)41-24-36(47)42-28(4)38(49)43-34(40(51)52)23-33-26(2)20-32(46)21-27(33)3/h6-11,14-17,20-21,28,31,34-35,46H,5,12-13,18-19,22-25H2,1-4H3,(H,41,50)(H,42,47)(H,43,49)(H,51,52)/t28-,31?,34+,35+/m1/s1 ZRGJOXHHIRWPHY-AXCNTNFBSA-N 50500612 CHEMBL3754081 Mu-type opioid receptor Cavia cutleri 0.730000 ChEMBL 10.1016/j.bmcl.2015.10.081 10.7270/Q2W66PSM 26611918 Deekonda, S; Cole, J; Sunna, S; Rankin, D; Largent-Milnes, TM; Davis, P; BassiriRad, NM; Lai, J; Vanderah, TW; Porecca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500612 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500612&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 127035665 433912513 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51218315 CCC(=O)N(CC1CCCCN1CCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@H](C)C(=O)N[C@@H](Cc1c(C)cc(O)cc1C)C(O)=O)c1ccccc1 InChI=1S/C43H56N6O8/c1-5-40(53)49(32-16-10-7-11-17-32)27-33-18-12-13-20-48(33)21-19-38(51)46-36(24-31-14-8-6-9-15-31)42(55)44-26-39(52)45-30(4)41(54)47-37(43(56)57)25-35-28(2)22-34(50)23-29(35)3/h6-11,14-17,22-23,30,33,36-37,50H,5,12-13,18-21,24-27H2,1-4H3,(H,44,55)(H,45,52)(H,46,51)(H,47,54)(H,56,57)/t30-,33?,36+,37+/m1/s1 CPLFVGPHVVDKDM-YBKIDQFESA-N 50500609 CHEMBL3754056 Mu-type opioid receptor Cavia cutleri 4.1 ChEMBL 10.1016/j.bmcl.2015.10.081 10.7270/Q2W66PSM 26611918 Deekonda, S; Cole, J; Sunna, S; Rankin, D; Largent-Milnes, TM; Davis, P; BassiriRad, NM; Lai, J; Vanderah, TW; Porecca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500609 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500609&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 127035666 433912510 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51218317 CCC(=O)N(CC1CCCCN1Cc1ccc2[C@H](N)CCCc2c1)c1ccccc1 InChI=1S/C26H35N3O/c1-2-26(30)29(22-10-4-3-5-11-22)19-23-12-6-7-16-28(23)18-20-14-15-24-21(17-20)9-8-13-25(24)27/h3-5,10-11,14-15,17,23,25H,2,6-9,12-13,16,18-19,27H2,1H3/t23?,25-/m1/s1 HHUFGVRUAGSDNE-XSWBTSGESA-N 50500610 CHEMBL3754245 Mu-type opioid receptor Cavia cutleri 1005 ChEMBL 10.1016/j.bmcl.2015.10.081 10.7270/Q2W66PSM 26611918 Deekonda, S; Cole, J; Sunna, S; Rankin, D; Largent-Milnes, TM; Davis, P; BassiriRad, NM; Lai, J; Vanderah, TW; Porecca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50500610 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50500610&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 127036745 433912511 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51212857 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(F)cc1)C(=O)OCc1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C32H31F7N4O6/c1-17(42-29(47)25(40)12-18-4-8-24(44)9-5-18)28(46)41-15-27(45)43-26(13-19-2-6-23(33)7-3-19)30(48)49-16-20-10-21(31(34,35)36)14-22(11-20)32(37,38)39/h2-11,14,17,25-26,44H,12-13,15-16,40H2,1H3,(H,41,46)(H,42,47)(H,43,45)/t17-,25+,26+/m1/s1 ZASPFNTXFLESNS-PLZPTFKGSA-N 50498568 CHEMBL3609618 Mu-type opioid receptor Cavia cutleri 210 ChEMBL 10.1016/j.bmcl.2015.06.030 10.7270/Q2R78J7N 26212775 Nair, P; Yamamoto, T; Cowell, S; Kulkarni, V; Moye, S; Navratilova, E; Davis, P; Ma, SW; Vanderah, TW; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50498568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50498568&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 122187723 433910470 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51212861 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C34H33F6N5O6/c1-18(44-31(49)26(41)12-19-6-8-24(46)9-7-19)30(48)43-16-29(47)45-28(13-21-15-42-27-5-3-2-4-25(21)27)32(50)51-17-20-10-22(33(35,36)37)14-23(11-20)34(38,39)40/h2-11,14-15,18,26,28,42,46H,12-13,16-17,41H2,1H3,(H,43,48)(H,44,49)(H,45,47)/t18-,26+,28+/m1/s1 VUBAEISRKSELTE-OGPKSRJFSA-N 50498569 CHEMBL3609617 Mu-type opioid receptor Cavia cutleri 840 ChEMBL 10.1016/j.bmcl.2015.06.030 10.7270/Q2R78J7N 26212775 Nair, P; Yamamoto, T; Cowell, S; Kulkarni, V; Moye, S; Navratilova, E; Davis, P; Ma, SW; Vanderah, TW; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50498569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50498569&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44176572 433910471 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51212866 CCCCC(NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C49H53F6N7O8/c1-3-4-13-39(45(67)62-41(23-32-25-57-38-14-9-8-12-36(32)38)47(69)70-27-31-19-33(48(50,51)52)24-34(20-31)49(53,54)55)61-46(68)40(22-29-10-6-5-7-11-29)60-42(64)26-58-43(65)28(2)59-44(66)37(56)21-30-15-17-35(63)18-16-30/h5-12,14-20,24-25,28,37,39-41,57,63H,3-4,13,21-23,26-27,56H2,1-2H3,(H,58,65)(H,59,66)(H,60,64)(H,61,68)(H,62,67)/t28-,37+,39?,40+,41+/m1/s1 HNLXDBKQNYDVCI-WFKCRPRESA-N 50498570 CHEMBL3608938 Mu-type opioid receptor Cavia cutleri 1100 ChEMBL 10.1016/j.bmcl.2015.06.030 10.7270/Q2R78J7N 26212775 Nair, P; Yamamoto, T; Cowell, S; Kulkarni, V; Moye, S; Navratilova, E; Davis, P; Ma, SW; Vanderah, TW; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50498570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50498570&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 122187205 433910472 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51212872 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(F)cc1)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C45H44F7N7O8/c1-24(57-41(64)34(53)16-25-8-12-32(60)13-9-25)40(63)55-21-38(61)58-36(17-26-6-10-31(46)11-7-26)42(65)56-22-39(62)59-37(18-28-20-54-35-5-3-2-4-33(28)35)43(66)67-23-27-14-29(44(47,48)49)19-30(15-27)45(50,51)52/h2-15,19-20,24,34,36-37,54,60H,16-18,21-23,53H2,1H3,(H,55,63)(H,56,65)(H,57,64)(H,58,61)(H,59,62)/t24-,34+,36+,37+/m1/s1 NKULLHQHASCPKR-CDYHHZRJSA-N 50498575 CHEMBL3608939 Mu-type opioid receptor Cavia cutleri 60 ChEMBL 10.1016/j.bmcl.2015.06.030 10.7270/Q2R78J7N 26212775 Nair, P; Yamamoto, T; Cowell, S; Kulkarni, V; Moye, S; Navratilova, E; Davis, P; Ma, SW; Vanderah, TW; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50498575 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50498575&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 122187206 433910477 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51212873 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C43H42F6N6O7/c1-24(53-39(59)33(50)17-26-11-13-31(56)14-12-26)38(58)52-22-37(57)54-35(18-25-7-3-2-4-8-25)40(60)55-36(19-28-21-51-34-10-6-5-9-32(28)34)41(61)62-23-27-15-29(42(44,45)46)20-30(16-27)43(47,48)49/h2-16,20-21,24,33,35-36,51,56H,17-19,22-23,50H2,1H3,(H,52,58)(H,53,59)(H,54,57)(H,55,60)/t24-,33+,35+,36+/m1/s1 IQGTUPXJLRMAOA-OHQNULFHSA-N 50498572 CHEMBL3609616 Mu-type opioid receptor Cavia cutleri 520 ChEMBL 10.1016/j.bmcl.2015.06.030 10.7270/Q2R78J7N 26212775 Nair, P; Yamamoto, T; Cowell, S; Kulkarni, V; Moye, S; Navratilova, E; Davis, P; Ma, SW; Vanderah, TW; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50498572 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50498572&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44176456 433910474 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51212904 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(Cl)cc1)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C45H44ClF6N7O8/c1-24(57-41(64)34(53)16-25-8-12-32(60)13-9-25)40(63)55-21-38(61)58-36(17-26-6-10-31(46)11-7-26)42(65)56-22-39(62)59-37(18-28-20-54-35-5-3-2-4-33(28)35)43(66)67-23-27-14-29(44(47,48)49)19-30(15-27)45(50,51)52/h2-15,19-20,24,34,36-37,54,60H,16-18,21-23,53H2,1H3,(H,55,63)(H,56,65)(H,57,64)(H,58,61)(H,59,62)/t24-,34+,36+,37+/m1/s1 MTTXEONPPSHVNT-CDYHHZRJSA-N 50498574 CHEMBL3609615 Mu-type opioid receptor Cavia cutleri 120 ChEMBL 10.1016/j.bmcl.2015.06.030 10.7270/Q2R78J7N 26212775 Nair, P; Yamamoto, T; Cowell, S; Kulkarni, V; Moye, S; Navratilova, E; Davis, P; Ma, SW; Vanderah, TW; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50498574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50498574&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 122187722 433910476 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51212919 C[C@@H](NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C34H35F6N5O4/c1-17-8-24(46)9-18(2)26(17)14-27(41)31(48)44-19(3)30(47)45-29(12-21-16-42-28-7-5-4-6-25(21)28)32(49)43-15-20-10-22(33(35,36)37)13-23(11-20)34(38,39)40/h4-11,13,16,19,27,29,42,46H,12,14-15,41H2,1-3H3,(H,43,49)(H,44,48)(H,45,47)/t19-,27+,29+/m1/s1 HVVQYXZAJOSRJZ-FNFCYJGBSA-N 50498571 CHEMBL3609621 Mu-type opioid receptor Cavia cutleri 120 ChEMBL 10.1016/j.bmcl.2015.06.030 10.7270/Q2R78J7N 26212775 Nair, P; Yamamoto, T; Cowell, S; Kulkarni, V; Moye, S; Navratilova, E; Davis, P; Ma, SW; Vanderah, TW; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50498571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50498571&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 122187725 433910473 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51212923 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C46H47F6N7O8/c1-26(57-42(64)35(53)19-28-11-13-33(60)14-12-28)41(63)56-24-40(62)58-37(20-27-7-3-2-4-8-27)43(65)54-16-15-39(61)59-38(21-30-23-55-36-10-6-5-9-34(30)36)44(66)67-25-29-17-31(45(47,48)49)22-32(18-29)46(50,51)52/h2-14,17-18,22-23,26,35,37-38,55,60H,15-16,19-21,24-25,53H2,1H3,(H,54,65)(H,56,63)(H,57,64)(H,58,62)(H,59,61)/t26-,35+,37+,38+/m1/s1 GVRKQRSTDMXZGX-VAQUTSCRSA-N 50498576 CHEMBL3608937 Mu-type opioid receptor Cavia cutleri 430 ChEMBL 10.1016/j.bmcl.2015.06.030 10.7270/Q2R78J7N 26212775 Nair, P; Yamamoto, T; Cowell, S; Kulkarni, V; Moye, S; Navratilova, E; Davis, P; Ma, SW; Vanderah, TW; Lai, J; Porreca, F; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50498576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50498576&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44177770 433910478 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51214098 CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)N(C)C(=O)CNC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C55H63F6N9O8/c1-31(2)21-43(51(76)67-44(26-36-29-63-42-14-9-8-13-40(36)42)50(75)64-28-35-22-37(54(56,57)58)27-38(23-35)55(59,60)61)68-52(77)45-15-10-20-70(45)53(78)46(25-33-11-6-5-7-12-33)69(4)47(72)30-65-48(73)32(3)66-49(74)41(62)24-34-16-18-39(71)19-17-34/h5-9,11-14,16-19,22-23,27,29,31-32,41,43-46,63,71H,10,15,20-21,24-26,28,30,62H2,1-4H3,(H,64,75)(H,65,73)(H,66,74)(H,67,76)(H,68,77)/t32-,41-,43-,44-,45-,46-/m0/s1 PEUVJNALVBXTKV-MJEAINFQSA-N 50499065 CHEMBL4299466 Mu-type opioid receptor Cavia cutleri 230 ChEMBL 10.1021/acs.jmedchem.5b01170 10.7270/Q2VT1W34 26465170 Giri, AK; Apostol, CR; Wang, Y; Forte, BL; Largent-Milnes, TM; Davis, P; Rankin, D; Molnar, G; Olson, KM; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499065&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145948955 433910967 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51214099 CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C56H64ClF6N9O8/c1-29(2)17-44(52(78)70-45(23-35-27-65-43-10-7-6-9-40(35)43)51(77)66-26-34-20-36(55(58,59)60)24-37(21-34)56(61,62)63)71-53(79)47-11-8-16-72(47)54(80)46(22-33-12-14-38(57)15-13-33)69-48(74)28-67-49(75)32(5)68-50(76)42(64)25-41-30(3)18-39(73)19-31(41)4/h6-7,9-10,12-15,18-21,24,27,29,32,42,44-47,65,73H,8,11,16-17,22-23,25-26,28,64H2,1-5H3,(H,66,77)(H,67,75)(H,68,76)(H,69,74)(H,70,78)(H,71,79)/t32-,42-,44-,45-,46-,47-/m0/s1 VAQZSLXHGCOMAT-OLBHHIGCSA-N 50499064 CHEMBL4299483 Mu-type opioid receptor Cavia cutleri 166 ChEMBL 10.1021/acs.jmedchem.5b01170 10.7270/Q2VT1W34 26465170 Giri, AK; Apostol, CR; Wang, Y; Forte, BL; Largent-Milnes, TM; Davis, P; Rankin, D; Molnar, G; Olson, KM; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499064&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145948981 433910966 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51214112 CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)N(C)C(=O)CNC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C57H67F6N9O8/c1-31(2)19-45(53(78)69-46(25-37-29-65-44-16-11-10-15-41(37)44)52(77)66-28-36-22-38(56(58,59)60)26-39(23-36)57(61,62)63)70-54(79)47-17-12-18-72(47)55(80)48(24-35-13-8-7-9-14-35)71(6)49(74)30-67-50(75)34(5)68-51(76)43(64)27-42-32(3)20-40(73)21-33(42)4/h7-11,13-16,20-23,26,29,31,34,43,45-48,65,73H,12,17-19,24-25,27-28,30,64H2,1-6H3,(H,66,77)(H,67,75)(H,68,76)(H,69,78)(H,70,79)/t34-,43-,45-,46-,47-,48-/m0/s1 VQUPRWGMQYINPZ-CTZPLLSNSA-N 50499066 CHEMBL4299371 Mu-type opioid receptor Cavia cutleri 21 ChEMBL 10.1021/acs.jmedchem.5b01170 10.7270/Q2VT1W34 26465170 Giri, AK; Apostol, CR; Wang, Y; Forte, BL; Largent-Milnes, TM; Davis, P; Rankin, D; Molnar, G; Olson, KM; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499066&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145948744 433910968 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51214116 CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C54H61F6N9O8/c1-30(2)20-42(50(75)67-43(25-35-28-62-41-13-8-7-12-39(35)41)49(74)63-27-34-21-36(53(55,56)57)26-37(22-34)54(58,59)60)68-51(76)45-14-9-19-69(45)52(77)44(24-32-10-5-4-6-11-32)66-46(71)29-64-47(72)31(3)65-48(73)40(61)23-33-15-17-38(70)18-16-33/h4-8,10-13,15-18,21-22,26,28,30-31,40,42-45,62,70H,9,14,19-20,23-25,27,29,61H2,1-3H3,(H,63,74)(H,64,72)(H,65,73)(H,66,71)(H,67,75)(H,68,76)/t31-,40+,42+,43+,44+,45+/m1/s1 LWOMHJBSXPGKKS-REAJPLCASA-N 21012 (2S)-2-{[(2S)-1-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-({[3,5-bis(trifluoromethyl)phenyl]methyl}carbamoyl)-2-(1H-indol-3-yl)ethyl]-4-methylpentanamide::C-terminal modified bifunctional peptide, 5::H-Tyr-D-Ala-Gly-Phe-Pro-Leu-Trp-NH-3,5-Bzl(CF3)2 Mu-type opioid receptor Cavia cutleri 350 ChEMBL 10.1021/acs.jmedchem.5b01170 10.7270/Q2VT1W34 26465170 Giri, AK; Apostol, CR; Wang, Y; Forte, BL; Largent-Milnes, TM; Davis, P; Rankin, D; Molnar, G; Olson, KM; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21012&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 24768355 49689085 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51214117 CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccc(F)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C56H64F7N9O8/c1-29(2)17-44(52(78)70-45(23-35-27-65-43-10-7-6-9-40(35)43)51(77)66-26-34-20-36(55(58,59)60)24-37(21-34)56(61,62)63)71-53(79)47-11-8-16-72(47)54(80)46(22-33-12-14-38(57)15-13-33)69-48(74)28-67-49(75)32(5)68-50(76)42(64)25-41-30(3)18-39(73)19-31(41)4/h6-7,9-10,12-15,18-21,24,27,29,32,42,44-47,65,73H,8,11,16-17,22-23,25-26,28,64H2,1-5H3,(H,66,77)(H,67,75)(H,68,76)(H,69,74)(H,70,78)(H,71,79)/t32-,42-,44-,45-,46-,47-/m0/s1 SKSVLYVQUOGPSM-OLBHHIGCSA-N 50499071 CHEMBL4299423 Mu-type opioid receptor Cavia cutleri 42 ChEMBL 10.1021/acs.jmedchem.5b01170 10.7270/Q2VT1W34 26465170 Giri, AK; Apostol, CR; Wang, Y; Forte, BL; Largent-Milnes, TM; Davis, P; Rankin, D; Molnar, G; Olson, KM; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499071&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145948847 433910973 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51214118 CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccc(F)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C54H60F7N9O8/c1-29(2)19-42(50(76)68-43(24-34-27-63-41-8-5-4-7-39(34)41)49(75)64-26-33-20-35(53(56,57)58)25-36(21-33)54(59,60)61)69-51(77)45-9-6-18-70(45)52(78)44(23-32-10-14-37(55)15-11-32)67-46(72)28-65-47(73)30(3)66-48(74)40(62)22-31-12-16-38(71)17-13-31/h4-5,7-8,10-17,20-21,25,27,29-30,40,42-45,63,71H,6,9,18-19,22-24,26,28,62H2,1-3H3,(H,64,75)(H,65,73)(H,66,74)(H,67,72)(H,68,76)(H,69,77)/t30-,40-,42-,43-,44-,45-/m0/s1 IQKIYBUXSZWUTP-MHCDBONUSA-N 50499067 CHEMBL4299479 Mu-type opioid receptor Cavia cutleri 65 ChEMBL 10.1021/acs.jmedchem.5b01170 10.7270/Q2VT1W34 26465170 Giri, AK; Apostol, CR; Wang, Y; Forte, BL; Largent-Milnes, TM; Davis, P; Rankin, D; Molnar, G; Olson, KM; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499067&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145948968 433910969 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51214119 CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccc(Br)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C56H64BrF6N9O8/c1-29(2)17-44(52(78)70-45(23-35-27-65-43-10-7-6-9-40(35)43)51(77)66-26-34-20-36(55(58,59)60)24-37(21-34)56(61,62)63)71-53(79)47-11-8-16-72(47)54(80)46(22-33-12-14-38(57)15-13-33)69-48(74)28-67-49(75)32(5)68-50(76)42(64)25-41-30(3)18-39(73)19-31(41)4/h6-7,9-10,12-15,18-21,24,27,29,32,42,44-47,65,73H,8,11,16-17,22-23,25-26,28,64H2,1-5H3,(H,66,77)(H,67,75)(H,68,76)(H,69,74)(H,70,78)(H,71,79)/t32-,42-,44-,45-,46-,47-/m0/s1 NGTSXDWOKUNRLY-OLBHHIGCSA-N 50499072 CHEMBL4299476 Mu-type opioid receptor Cavia cutleri 460 ChEMBL 10.1021/acs.jmedchem.5b01170 10.7270/Q2VT1W34 26465170 Giri, AK; Apostol, CR; Wang, Y; Forte, BL; Largent-Milnes, TM; Davis, P; Rankin, D; Molnar, G; Olson, KM; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499072&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145948965 433910974 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51214168 CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccc(F)cc1)N(C)C(=O)CNC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C57H66F7N9O8/c1-30(2)18-45(53(79)70-46(24-36-28-66-44-11-8-7-10-41(36)44)52(78)67-27-35-21-37(56(59,60)61)25-38(22-35)57(62,63)64)71-54(80)47-12-9-17-73(47)55(81)48(23-34-13-15-39(58)16-14-34)72(6)49(75)29-68-50(76)33(5)69-51(77)43(65)26-42-31(3)19-40(74)20-32(42)4/h7-8,10-11,13-16,19-22,25,28,30,33,43,45-48,66,74H,9,12,17-18,23-24,26-27,29,65H2,1-6H3,(H,67,78)(H,68,76)(H,69,77)(H,70,79)(H,71,80)/t33-,43-,45-,46-,47-,48-/m0/s1 COKDWHNHZYOASY-LPAMGJINSA-N 50499070 CHEMBL4299415 Mu-type opioid receptor Cavia cutleri 77 ChEMBL 10.1021/acs.jmedchem.5b01170 10.7270/Q2VT1W34 26465170 Giri, AK; Apostol, CR; Wang, Y; Forte, BL; Largent-Milnes, TM; Davis, P; Rankin, D; Molnar, G; Olson, KM; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499070 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499070&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145948839 433910972 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51214176 CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C56H65F6N9O8/c1-30(2)18-44(52(77)69-45(24-36-28-64-43-15-10-9-14-40(36)43)51(76)65-27-35-21-37(55(57,58)59)25-38(22-35)56(60,61)62)70-53(78)47-16-11-17-71(47)54(79)46(23-34-12-7-6-8-13-34)68-48(73)29-66-49(74)33(5)67-50(75)42(63)26-41-31(3)19-39(72)20-32(41)4/h6-10,12-15,19-22,25,28,30,33,42,44-47,64,72H,11,16-18,23-24,26-27,29,63H2,1-5H3,(H,65,76)(H,66,74)(H,67,75)(H,68,73)(H,69,77)(H,70,78)/t33-,42-,44-,45-,46-,47-/m0/s1 UQHGZONWCQCFEK-WYLKAJGDSA-N 50499069 CHEMBL4299390 Mu-type opioid receptor Cavia cutleri 81 ChEMBL 10.1021/acs.jmedchem.5b01170 10.7270/Q2VT1W34 26465170 Giri, AK; Apostol, CR; Wang, Y; Forte, BL; Largent-Milnes, TM; Davis, P; Rankin, D; Molnar, G; Olson, KM; Porreca, F; Vanderah, TW; Hruby, VJ University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499069 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499069&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 145948797 433910971 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51269505 CCN1CCN([C@@H]2[C@H](CCC[C@H]12)N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C22H31Cl2N3O/c1-2-25-12-13-27(21(28)15-16-8-9-17(23)18(24)14-16)22-19(25)6-5-7-20(22)26-10-3-4-11-26/h8-9,14,19-20,22H,2-7,10-13,15H2,1H3/t19-,20-,22-/m0/s1 IPKVFDXSTVEXOJ-ONTIZHBOSA-N 50518461 CHEMBL4467644 Mu-type opioid receptor Cavia cutleri 3300 ChEMBL 10.1021/acs.jmedchem.8b01609 10.7270/Q2F47SHX 30543421 Tangherlini, G; Kalinin, DV; Schepmann, D; Che, T; Mykicki, N; Ständer, S; Loser, K; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50518461 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50518461&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 155532812 440727043 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51269520 Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1 UZHSEJADLWPNLE-GRGSLBFTSA-N 50000788 (morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(naloxone) 4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::(naloxone)4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::(naloxone)4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one (naloxone)::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one( Naloxone)::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(Naxolone)::4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(naloxone)C2H2O4::Analog of 14-(Arylhydroxyamino)codeinone::NALOXONE::NARCAN::SUBOXONE::[17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydroxymorphinan-6-one Mu-type opioid receptor Cavia cutleri 2.3 ChEMBL 10.1021/acs.jmedchem.8b01609 10.7270/Q2F47SHX 30543421 Tangherlini, G; Kalinin, DV; Schepmann, D; Che, T; Mykicki, N; Ständer, S; Loser, K; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000788&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5284596 103915330 7459 DB01183 1676 C07252 ZINC00389747 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51269521 FCCCc1cn(CC(=O)N2CCN([C@@H]3[C@H](CCC[C@H]23)N2CCCC2)C(=O)Cc2ccc(Cl)c(Cl)c2)nn1 InChI=1S/C27H35Cl2FN6O2/c28-21-9-8-19(15-22(21)29)16-25(37)36-14-13-35(26(38)18-34-17-20(31-32-34)5-4-10-30)24-7-3-6-23(27(24)36)33-11-1-2-12-33/h8-9,15,17,23-24,27H,1-7,10-14,16,18H2/t23-,24-,27+/m0/s1 XPPNLEJFCXIJTB-NLJOTIRTSA-N 50518469 CHEMBL4518180 Mu-type opioid receptor Cavia cutleri 947 ChEMBL 10.1021/acs.jmedchem.8b01609 10.7270/Q2F47SHX 30543421 Tangherlini, G; Kalinin, DV; Schepmann, D; Che, T; Mykicki, N; Ständer, S; Loser, K; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50518469 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50518469&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 155541251 440727051 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51269522 CCCCN1CCN([C@@H]2[C@H](CCC[C@H]12)N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C24H35Cl2N3O/c1-2-3-11-28-14-15-29(23(30)17-18-9-10-19(25)20(26)16-18)24-21(7-6-8-22(24)28)27-12-4-5-13-27/h9-10,16,21-22,24H,2-8,11-15,17H2,1H3/t21-,22-,24+/m0/s1 QZYMRJVVDVLWFH-WPFOTENUSA-N 50518464 CHEMBL4561040 Mu-type opioid receptor Cavia cutleri 2600 ChEMBL 10.1021/acs.jmedchem.8b01609 10.7270/Q2F47SHX 30543421 Tangherlini, G; Kalinin, DV; Schepmann, D; Che, T; Mykicki, N; Ständer, S; Loser, K; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50518464 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50518464&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 155558339 440727046 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51269523 CCCN1CCN([C@@H]2[C@H](CCC[C@H]12)N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C23H33Cl2N3O/c1-2-10-26-13-14-28(22(29)16-17-8-9-18(24)19(25)15-17)23-20(26)6-5-7-21(23)27-11-3-4-12-27/h8-9,15,20-21,23H,2-7,10-14,16H2,1H3/t20-,21-,23-/m0/s1 USWUHUMBTVHBPD-FUDKSRODSA-N 50518465 CHEMBL4582146 Mu-type opioid receptor Cavia cutleri 407 ChEMBL 10.1021/acs.jmedchem.8b01609 10.7270/Q2F47SHX 30543421 Tangherlini, G; Kalinin, DV; Schepmann, D; Che, T; Mykicki, N; Ständer, S; Loser, K; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50518465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50518465&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 155562055 440727047 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51269560 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 5.2 ChEMBL 10.1021/acs.jmedchem.8b01609 10.7270/Q2F47SHX 30543421 Tangherlini, G; Kalinin, DV; Schepmann, D; Che, T; Mykicki, N; Ständer, S; Loser, K; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51269561 FCCn1cc(CN2CCN([C@@H]3[C@H](CCC[C@H]23)N2CCCC2)C(=O)Cc2ccc(Cl)c(Cl)c2)nn1 InChI=1S/C25H33Cl2FN6O/c26-20-7-6-18(14-21(20)27)15-24(35)34-13-12-32(16-19-17-33(11-8-28)30-29-19)23-5-3-4-22(25(23)34)31-9-1-2-10-31/h6-7,14,17,22-23,25H,1-5,8-13,15-16H2/t22-,23-,25+/m0/s1 QGINONNTZRVLHI-SONWIMMPSA-N 50518466 CHEMBL4463652 Mu-type opioid receptor Cavia cutleri 573 ChEMBL 10.1021/acs.jmedchem.8b01609 10.7270/Q2F47SHX 30543421 Tangherlini, G; Kalinin, DV; Schepmann, D; Che, T; Mykicki, N; Ständer, S; Loser, K; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50518466 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50518466&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 155530173 440727048 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51269564 CC(C)(C)OC(=O)N1CCN([C@@H]2[C@H](CCC[C@H]12)N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C25H35Cl2N3O3/c1-25(2,3)33-24(32)29-13-14-30(22(31)16-17-9-10-18(26)19(27)15-17)23-20(7-6-8-21(23)29)28-11-4-5-12-28/h9-10,15,20-21,23H,4-8,11-14,16H2,1-3H3/t20-,21-,23+/m0/s1 QYKOMVKBDKOREW-QNWVGRARSA-N 50518462 CHEMBL4483681 Mu-type opioid receptor Cavia cutleri 260 ChEMBL 10.1021/acs.jmedchem.8b01609 10.7270/Q2F47SHX 30543421 Tangherlini, G; Kalinin, DV; Schepmann, D; Che, T; Mykicki, N; Ständer, S; Loser, K; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50518462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50518462&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 117707041 440727044 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51277600 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@@H]1CCNc2ccc(Cc3ccccc3)cc12 InChI=1S/C27H31N3O2/c1-17-12-21(31)13-18(2)22(17)16-24(28)27(32)30-26-10-11-29-25-9-8-20(15-23(25)26)14-19-6-4-3-5-7-19/h3-9,12-13,15,24,26,29,31H,10-11,14,16,28H2,1-2H3,(H,30,32)/t24-,26+/m0/s1 VTFUYBNMSGPAQU-AZGAKELHSA-N 50427556 CHEMBL2322568 Mu-type opioid receptor Cavia cutleri 0.220000 ChEMBL 10.1021/acs.jmedchem.9b00219 10.7270/Q23R0X7F 30924650 Henry, SP; Fernandez, TJ; Anand, JP; Griggs, NW; Traynor, JR; Mosberg, HI University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50427556 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50427556&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10320450 164156431 CHEMBL2322568 ZINC26646695 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51277796 C(N[C@H]1CC[C@@]2(CC1)OCCc1ccccc21)C1CCCCC1 InChI=1S/C21H31NO/c1-2-6-17(7-3-1)16-22-19-10-13-21(14-11-19)20-9-5-4-8-18(20)12-15-23-21/h4-5,8-9,17,19,22H,1-3,6-7,10-16H2/t19-,21- AQZKAHGFUOVNTK-XUTJKUGGSA-N 50521510 CHEMBL4472927 Mu-type opioid receptor Cavia cutleri 114 ChEMBL 10.1021/acs.jmedchem.9b00449 10.7270/Q2KS6VZ0 30939014 Kronenberg, E; Weber, F; Brune, S; Schepmann, D; Almansa, C; Friedland, K; Laurini, E; Pricl, S; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50521510 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50521510&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 155535978 440730092 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51277801 CCOC1Cc2ccccc2[C@@]2(CC[C@@H](CC2)N(C)CC2CCCCC2)O1 InChI=1S/C24H37NO2/c1-3-26-23-17-20-11-7-8-12-22(20)24(27-23)15-13-21(14-16-24)25(2)18-19-9-5-4-6-10-19/h7-8,11-12,19,21,23H,3-6,9-10,13-18H2,1-2H3/t21-,23?,24- IKMGBUAQTLFZNA-UCWUDVSLSA-N 50521513 CHEMBL4443319 Mu-type opioid receptor Cavia cutleri 879 ChEMBL 10.1021/acs.jmedchem.9b00449 10.7270/Q2KS6VZ0 30939014 Kronenberg, E; Weber, F; Brune, S; Schepmann, D; Almansa, C; Friedland, K; Laurini, E; Pricl, S; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50521513 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50521513&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 155516317 440730095 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51277840 C(N[C@H]1CC[C@@]2(CC1)OC=Cc1ccccc21)C1CCCCC1 InChI=1S/C21H29NO/c1-2-6-17(7-3-1)16-22-19-10-13-21(14-11-19)20-9-5-4-8-18(20)12-15-23-21/h4-5,8-9,12,15,17,19,22H,1-3,6-7,10-11,13-14,16H2/t19-,21- OJYGYOYQVVGKTL-XUTJKUGGSA-N 50521511 CHEMBL4562511 Mu-type opioid receptor Cavia cutleri 258 ChEMBL 10.1021/acs.jmedchem.9b00449 10.7270/Q2KS6VZ0 30939014 Kronenberg, E; Weber, F; Brune, S; Schepmann, D; Almansa, C; Friedland, K; Laurini, E; Pricl, S; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50521511 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50521511&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 155558857 440730093 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51277841 CN(CC1CCCCC1)[C@H]1CC[C@@]2(CC1)OC=Cc1ccccc21 InChI=1S/C22H31NO/c1-23(17-18-7-3-2-4-8-18)20-11-14-22(15-12-20)21-10-6-5-9-19(21)13-16-24-22/h5-6,9-10,13,16,18,20H,2-4,7-8,11-12,14-15,17H2,1H3/t20-,22- DFGZNCBJYISTLB-AQYVVDRMSA-N 50521528 CHEMBL4577975 Mu-type opioid receptor Cavia cutleri 163 ChEMBL 10.1021/acs.jmedchem.9b00449 10.7270/Q2KS6VZ0 30939014 Kronenberg, E; Weber, F; Brune, S; Schepmann, D; Almansa, C; Friedland, K; Laurini, E; Pricl, S; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50521528 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50521528&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 155524132 440730110 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51277842 CCOC1Cc2ccccc2[C@@]2(CC[C@@H](CC2)NCC2CCCCC2)O1 InChI=1S/C23H35NO2/c1-2-25-22-16-19-10-6-7-11-21(19)23(26-22)14-12-20(13-15-23)24-17-18-8-4-3-5-9-18/h6-7,10-11,18,20,22,24H,2-5,8-9,12-17H2,1H3/t20-,22?,23- LKSVIRCJQQMHGO-FXCIWXGGSA-N 50521514 CHEMBL4532845 Mu-type opioid receptor Cavia cutleri 185 ChEMBL 10.1021/acs.jmedchem.9b00449 10.7270/Q2KS6VZ0 30939014 Kronenberg, E; Weber, F; Brune, S; Schepmann, D; Almansa, C; Friedland, K; Laurini, E; Pricl, S; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50521514 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50521514&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 155547337 440730096 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51277843 CCOC1Cc2ccccc2[C@]2(CC[C@@H](CC2)NCC2CCCCC2)O1 InChI=1S/C23H35NO2/c1-2-25-22-16-19-10-6-7-11-21(19)23(26-22)14-12-20(13-15-23)24-17-18-8-4-3-5-9-18/h6-7,10-11,18,20,22,24H,2-5,8-9,12-17H2,1H3/t20-,22?,23+ LKSVIRCJQQMHGO-KFWDTITQSA-N 50521520 CHEMBL4562728 Mu-type opioid receptor Cavia cutleri 495 ChEMBL 10.1021/acs.jmedchem.9b00449 10.7270/Q2KS6VZ0 30939014 Kronenberg, E; Weber, F; Brune, S; Schepmann, D; Almansa, C; Friedland, K; Laurini, E; Pricl, S; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50521520 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50521520&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 155547337 440730102 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51277844 COC1Cc2ccccc2[C@@]2(CC[C@@H](CC2)N(C)CC2CCCCC2)O1 InChI=1S/C23H35NO2/c1-24(17-18-8-4-3-5-9-18)20-12-14-23(15-13-20)21-11-7-6-10-19(21)16-22(25-2)26-23/h6-7,10-11,18,20,22H,3-5,8-9,12-17H2,1-2H3/t20-,22?,23- MBRMOGQHSBUGKH-FXCIWXGGSA-N 50521523 CHEMBL4576927 Mu-type opioid receptor Cavia cutleri 299 ChEMBL 10.1021/acs.jmedchem.9b00449 10.7270/Q2KS6VZ0 30939014 Kronenberg, E; Weber, F; Brune, S; Schepmann, D; Almansa, C; Friedland, K; Laurini, E; Pricl, S; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50521523 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50521523&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 155553997 440730105 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51277845 COC1Cc2ccccc2[C@]2(CC[C@@H](CC2)N(C)CC2CCCCC2)O1 InChI=1S/C23H35NO2/c1-24(17-18-8-4-3-5-9-18)20-12-14-23(15-13-20)21-11-7-6-10-19(21)16-22(25-2)26-23/h6-7,10-11,18,20,22H,3-5,8-9,12-17H2,1-2H3/t20-,22?,23+ MBRMOGQHSBUGKH-KFWDTITQSA-N 50521529 CHEMBL4562252 Mu-type opioid receptor Cavia cutleri 391 ChEMBL 10.1021/acs.jmedchem.9b00449 10.7270/Q2KS6VZ0 30939014 Kronenberg, E; Weber, F; Brune, S; Schepmann, D; Almansa, C; Friedland, K; Laurini, E; Pricl, S; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50521529 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50521529&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 155553997 440730111 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51277846 COC1O[C@]2(CC[C@@H](CC2)NCC2CCCCC2)c2ccccc12 InChI=1S/C21H31NO2/c1-23-20-18-9-5-6-10-19(18)21(24-20)13-11-17(12-14-21)22-15-16-7-3-2-4-8-16/h5-6,9-10,16-17,20,22H,2-4,7-8,11-15H2,1H3/t17-,20?,21- XDSZKZOLLACLGI-WQUIYQLNSA-N 50521530 CHEMBL4483557 Mu-type opioid receptor Cavia cutleri 273 ChEMBL 10.1021/acs.jmedchem.9b00449 10.7270/Q2KS6VZ0 30939014 Kronenberg, E; Weber, F; Brune, S; Schepmann, D; Almansa, C; Friedland, K; Laurini, E; Pricl, S; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50521530 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50521530&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 155515524 440730112 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51277847 COC1O[C@]2(CC[C@@H](CC2)N(C)CC2CCCCC2)c2ccccc12 InChI=1S/C22H33NO2/c1-23(16-17-8-4-3-5-9-17)18-12-14-22(15-13-18)20-11-7-6-10-19(20)21(24-2)25-22/h6-7,10-11,17-18,21H,3-5,8-9,12-16H2,1-2H3/t18-,21?,22- UPNXBNHFBWGINS-NULPYHFVSA-N 50521512 CHEMBL4463331 Mu-type opioid receptor Cavia cutleri 231 ChEMBL 10.1021/acs.jmedchem.9b00449 10.7270/Q2KS6VZ0 30939014 Kronenberg, E; Weber, F; Brune, S; Schepmann, D; Almansa, C; Friedland, K; Laurini, E; Pricl, S; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50521512 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50521512&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 155529711 440730094 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51277848 COC1Cc2ccccc2[C@@]2(CC[C@@H](CC2)NCc2ccccc2)O1 InChI=1S/C22H27NO2/c1-24-21-15-18-9-5-6-10-20(18)22(25-21)13-11-19(12-14-22)23-16-17-7-3-2-4-8-17/h2-10,19,21,23H,11-16H2,1H3/t19-,21?,22- BITTYRNNBNMMOO-CTTUZFCVSA-N 50344429 CHEMBL1779993::trans-N-Benzyl-3-methoxy-3,4-dihydrospiro-[[2]benzopyran-1,1'-cyclohexan]-4'-amine Mu-type opioid receptor Cavia cutleri 38 ChEMBL 10.1021/acs.jmedchem.9b00449 10.7270/Q2KS6VZ0 30939014 Kronenberg, E; Weber, F; Brune, S; Schepmann, D; Almansa, C; Friedland, K; Laurini, E; Pricl, S; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344429 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344429&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 54582640 131347365 CHEMBL1779993 ZINC71340404 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51277849 COC1O[C@]2(CC[C@@H](CC2)NCc2ccccc2)c2ccccc12 InChI=1S/C21H25NO2/c1-23-20-18-9-5-6-10-19(18)21(24-20)13-11-17(12-14-21)22-15-16-7-3-2-4-8-16/h2-10,17,20,22H,11-15H2,1H3/t17-,20?,21- NCCWUSOQZYQVLQ-WQUIYQLNSA-N 50521526 CHEMBL4458895 Mu-type opioid receptor Cavia cutleri 115 ChEMBL 10.1021/acs.jmedchem.9b00449 10.7270/Q2KS6VZ0 30939014 Kronenberg, E; Weber, F; Brune, S; Schepmann, D; Almansa, C; Friedland, K; Laurini, E; Pricl, S; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50521526 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50521526&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 155512102 440730108 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51277850 C(N[C@H]1CC[C@@]2(CC1)OCCc1ccccc21)c1ccccc1 InChI=1S/C21H25NO/c1-2-6-17(7-3-1)16-22-19-10-13-21(14-11-19)20-9-5-4-8-18(20)12-15-23-21/h1-9,19,22H,10-16H2/t19-,21- PNRITCOEFRSXMM-XUTJKUGGSA-N 50521516 CHEMBL4469920 Mu-type opioid receptor Cavia cutleri 31 ChEMBL 10.1021/acs.jmedchem.9b00449 10.7270/Q2KS6VZ0 30939014 Kronenberg, E; Weber, F; Brune, S; Schepmann, D; Almansa, C; Friedland, K; Laurini, E; Pricl, S; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50521516 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50521516&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 155534365 440730098 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51277851 Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1 UZHSEJADLWPNLE-GRGSLBFTSA-N 50000788 (morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(naloxone) 4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::(naloxone)4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::(naloxone)4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one (naloxone)::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one( Naloxone)::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(Naxolone)::4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(naloxone)C2H2O4::Analog of 14-(Arylhydroxyamino)codeinone::NALOXONE::NARCAN::SUBOXONE::[17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydroxymorphinan-6-one Mu-type opioid receptor Cavia cutleri 2.1 ChEMBL 10.1021/acs.jmedchem.9b00449 10.7270/Q2KS6VZ0 30939014 Kronenberg, E; Weber, F; Brune, S; Schepmann, D; Almansa, C; Friedland, K; Laurini, E; Pricl, S; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000788&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5284596 103915330 7459 DB01183 1676 C07252 ZINC00389747 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51277889 COC1Cc2ccccc2[C@@]2(CC[C@@H](CC2)NCC2CCCCC2)O1 InChI=1S/C22H33NO2/c1-24-21-15-18-9-5-6-10-20(18)22(25-21)13-11-19(12-14-22)23-16-17-7-3-2-4-8-17/h5-6,9-10,17,19,21,23H,2-4,7-8,11-16H2,1H3/t19-,21?,22- QANFZJPWWAIUST-CTTUZFCVSA-N 50521509 CHEMBL4445822 Mu-type opioid receptor Cavia cutleri 354 ChEMBL 10.1021/acs.jmedchem.9b00449 10.7270/Q2KS6VZ0 30939014 Kronenberg, E; Weber, F; Brune, S; Schepmann, D; Almansa, C; Friedland, K; Laurini, E; Pricl, S; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50521509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50521509&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 155518065 440730091 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51277893 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 3.9 ChEMBL 10.1021/acs.jmedchem.9b00449 10.7270/Q2KS6VZ0 30939014 Kronenberg, E; Weber, F; Brune, S; Schepmann, D; Almansa, C; Friedland, K; Laurini, E; Pricl, S; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51277901 CCOC1Cc2ccccc2[C@]2(CC[C@@H](CC2)N(C)CC2CCCCC2)O1 InChI=1S/C24H37NO2/c1-3-26-23-17-20-11-7-8-12-22(20)24(27-23)15-13-21(14-16-24)25(2)18-19-9-5-4-6-10-19/h7-8,11-12,19,21,23H,3-6,9-10,13-18H2,1-2H3/t21-,23?,24+ IKMGBUAQTLFZNA-IQEXNZJNSA-N 50521521 CHEMBL4459303 Mu-type opioid receptor Cavia cutleri 297 ChEMBL 10.1021/acs.jmedchem.9b00449 10.7270/Q2KS6VZ0 30939014 Kronenberg, E; Weber, F; Brune, S; Schepmann, D; Almansa, C; Friedland, K; Laurini, E; Pricl, S; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50521521 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50521521&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 155516317 440730103 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51277902 COC1O[C@@]2(CC[C@@H](CC2)NCc2ccccc2)c2ccccc12 InChI=1S/C21H25NO2/c1-23-20-18-9-5-6-10-19(18)21(24-20)13-11-17(12-14-21)22-15-16-7-3-2-4-8-16/h2-10,17,20,22H,11-15H2,1H3/t17-,20?,21+ NCCWUSOQZYQVLQ-WQQJRXGJSA-N 50521531 CHEMBL4436757 Mu-type opioid receptor Cavia cutleri 768 ChEMBL 10.1021/acs.jmedchem.9b00449 10.7270/Q2KS6VZ0 30939014 Kronenberg, E; Weber, F; Brune, S; Schepmann, D; Almansa, C; Friedland, K; Laurini, E; Pricl, S; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50521531 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50521531&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 155512102 440730113 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51277915 CN(CC1CCCCC1)[C@H]1CC[C@]2(CC1)OC=Cc1ccccc21 InChI=1S/C22H31NO/c1-23(17-18-7-3-2-4-8-18)20-11-14-22(15-12-20)21-10-6-5-9-19(21)13-16-24-22/h5-6,9-10,13,16,18,20H,2-4,7-8,11-12,14-15,17H2,1H3/t20-,22+ DFGZNCBJYISTLB-GRGXKFILSA-N 50521519 CHEMBL4454365 Mu-type opioid receptor Cavia cutleri 391 ChEMBL 10.1021/acs.jmedchem.9b00449 10.7270/Q2KS6VZ0 30939014 Kronenberg, E; Weber, F; Brune, S; Schepmann, D; Almansa, C; Friedland, K; Laurini, E; Pricl, S; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50521519 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50521519&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 155524132 440730101 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51277916 COC1Cc2ccccc2[C@]2(CC[C@@H](CC2)NCC2CCCCC2)O1 InChI=1S/C22H33NO2/c1-24-21-15-18-9-5-6-10-20(18)22(25-21)13-11-19(12-14-22)23-16-17-7-3-2-4-8-17/h5-6,9-10,17,19,21,23H,2-4,7-8,11-16H2,1H3/t19-,21?,22+ QANFZJPWWAIUST-NDVHGFDXSA-N 50521522 CHEMBL4582223 Mu-type opioid receptor Cavia cutleri 462 ChEMBL 10.1021/acs.jmedchem.9b00449 10.7270/Q2KS6VZ0 30939014 Kronenberg, E; Weber, F; Brune, S; Schepmann, D; Almansa, C; Friedland, K; Laurini, E; Pricl, S; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50521522 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50521522&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 155518065 440730104 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51277917 COC1O[C@@]2(CC[C@@H](CC2)NCC2CCCCC2)c2ccccc12 InChI=1S/C21H31NO2/c1-23-20-18-9-5-6-10-19(18)21(24-20)13-11-17(12-14-21)22-15-16-7-3-2-4-8-16/h5-6,9-10,16-17,20,22H,2-4,7-8,11-15H2,1H3/t17-,20?,21+ XDSZKZOLLACLGI-WQQJRXGJSA-N 50521515 CHEMBL4441861 Mu-type opioid receptor Cavia cutleri 501 ChEMBL 10.1021/acs.jmedchem.9b00449 10.7270/Q2KS6VZ0 30939014 Kronenberg, E; Weber, F; Brune, S; Schepmann, D; Almansa, C; Friedland, K; Laurini, E; Pricl, S; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50521515 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50521515&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 155515524 440730097 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51277918 COC1Cc2ccccc2[C@@]2(CC[C@@H](CC2)N(C)Cc2ccccc2)O1 InChI=1S/C23H29NO2/c1-24(17-18-8-4-3-5-9-18)20-12-14-23(15-13-20)21-11-7-6-10-19(21)16-22(25-2)26-23/h3-11,20,22H,12-17H2,1-2H3/t20-,22?,23- AFKWCRVKGFPGQY-FXCIWXGGSA-N 50344435 CHEMBL1779999::trans-N-Benzyl-3-methoxy-N-methyl-3,4-dihydrospiro-[[2]benzopyran-1,1'-cyclohexan]-4'-amine Mu-type opioid receptor Cavia cutleri 41 ChEMBL 10.1021/acs.jmedchem.9b00449 10.7270/Q2KS6VZ0 30939014 Kronenberg, E; Weber, F; Brune, S; Schepmann, D; Almansa, C; Friedland, K; Laurini, E; Pricl, S; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344435 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344435&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 54583594 131347371 CHEMBL1779999 ZINC71332449 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51277935 C(N[C@H]1CC[C@]2(CC1)OCCc1ccccc21)C1CCCCC1 InChI=1S/C21H31NO/c1-2-6-17(7-3-1)16-22-19-10-13-21(14-11-19)20-9-5-4-8-18(20)12-15-23-21/h4-5,8-9,17,19,22H,1-3,6-7,10-16H2/t19-,21+ AQZKAHGFUOVNTK-TYKWCNGQSA-N 50521532 CHEMBL4557149 Mu-type opioid receptor Cavia cutleri 841 ChEMBL 10.1021/acs.jmedchem.9b00449 10.7270/Q2KS6VZ0 30939014 Kronenberg, E; Weber, F; Brune, S; Schepmann, D; Almansa, C; Friedland, K; Laurini, E; Pricl, S; Wünsch, B Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50521532 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50521532&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 155535978 440730114 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51297724 CC[C@@H]1CN2CCc3c([nH]c4cccc(OC)c34)[C@@H]2C[C@@H]1\C(=C/OC)C(=O)OC InChI=1S/C23H30N2O4/c1-5-14-12-25-10-9-15-21-18(7-6-8-20(21)28-3)24-22(15)19(25)11-16(14)17(13-27-2)23(26)29-4/h6-8,13-14,16,19,24H,5,9-12H2,1-4H3/b17-13+/t14-,16+,19+/m1/s1 LELBFTMXCIIKKX-QVRQZEMUSA-N 50474152 CHEBI:6956::CHEMBL299031 Mu-type opioid receptor Cavia cutleri 13 ChEMBL 10.1016/j.ejmech.2019.111701 10.7270/Q2668HN9 31550662 Turnaturi, R; Chiechio, S; Salerno, L; Rescifina, A; Pittalà, V; Cantarella, G; Tomarchio, E; Parenti, C; Pasquinucci, L University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50474152 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50474152&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3034396 433941417 C09226 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51297728 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 3.5 ChEMBL 10.1016/j.ejmech.2019.111701 10.7270/Q2668HN9 31550662 Turnaturi, R; Chiechio, S; Salerno, L; Rescifina, A; Pittalà, V; Cantarella, G; Tomarchio, E; Parenti, C; Pasquinucci, L University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51297752 CC[C@@H]1CN2CC[C@@]3(O)C(=Nc4cccc(OC)c34)[C@@H]2C[C@@H]1\C(=C/OC)C(=O)OC InChI=1S/C23H30N2O5/c1-5-14-12-25-10-9-23(27)20-17(7-6-8-19(20)29-3)24-21(23)18(25)11-15(14)16(13-28-2)22(26)30-4/h6-8,13-15,18,27H,5,9-12H2,1-4H3/b16-13+/t14-,15+,18+,23+/m1/s1 RYENLSMHLCNXJT-CYXFISRXSA-N 50474153 CHEMBL61630 Mu-type opioid receptor Cavia cutleri 53 ChEMBL 10.1016/j.ejmech.2019.111701 10.7270/Q2668HN9 31550662 Turnaturi, R; Chiechio, S; Salerno, L; Rescifina, A; Pittalà, V; Cantarella, G; Tomarchio, E; Parenti, C; Pasquinucci, L University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50474153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50474153&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44301524 433941418 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51297753 CC[C@@H]1CN2CC[C@@]3(O)C(=Nc4cccc(OC)c34)[C@@H]2C[C@@H]1\C(=C/OC)C(=O)OC InChI=1S/C23H30N2O5/c1-5-14-12-25-10-9-23(27)20-17(7-6-8-19(20)29-3)24-21(23)18(25)11-15(14)16(13-28-2)22(26)30-4/h6-8,13-15,18,27H,5,9-12H2,1-4H3/b16-13+/t14-,15+,18+,23+/m1/s1 RYENLSMHLCNXJT-CYXFISRXSA-N 50474153 CHEMBL61630 Mu-type opioid receptor Cavia cutleri 7.2 ChEMBL 10.1016/j.ejmech.2019.111701 10.7270/Q2668HN9 31550662 Turnaturi, R; Chiechio, S; Salerno, L; Rescifina, A; Pittalà, V; Cantarella, G; Tomarchio, E; Parenti, C; Pasquinucci, L University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50474153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50474153&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 44301524 433941418 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51297782 CC[C@@H]1CN2CCc3c([nH]c4cccc(OC)c34)[C@@H]2C[C@@H]1\C(=C/OC)C(=O)OC InChI=1S/C23H30N2O4/c1-5-14-12-25-10-9-15-21-18(7-6-8-20(21)28-3)24-22(15)19(25)11-16(14)17(13-27-2)23(26)29-4/h6-8,13-14,16,19,24H,5,9-12H2,1-4H3/b17-13+/t14-,16+,19+/m1/s1 LELBFTMXCIIKKX-QVRQZEMUSA-N 50474152 CHEBI:6956::CHEMBL299031 Mu-type opioid receptor Cavia cutleri 230 ChEMBL 10.1016/j.ejmech.2019.111701 10.7270/Q2668HN9 31550662 Turnaturi, R; Chiechio, S; Salerno, L; Rescifina, A; Pittalà, V; Cantarella, G; Tomarchio, E; Parenti, C; Pasquinucci, L University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50474152 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50474152&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 3034396 433941417 C09226 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51396633 C[C@H]1[C@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2CCc1ccccc1 InChI=1S/C22H27NO/c1-16-21-14-18-8-9-19(24)15-20(18)22(16,2)11-13-23(21)12-10-17-6-4-3-5-7-17/h3-9,15-16,21,24H,10-14H2,1-2H3/t16-,21+,22-/m0/s1 ZQHYKVKNPWDQSL-USCONSEESA-N 50001019 6,11-Dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL316632 Mu-type opioid receptor Cavia cutleri 55 ChEMBL 10.1016/j.ejmech.2020.112144 10.7270/Q2WM1J54 32087465 Xiong, J; Jin, J; Gao, L; Hao, C; Liu, X; Liu, BF; Chen, Y; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001019&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 23955939 103915552 CHEMBL316632 ZINC01481896 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51396634 C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCc1ccccc1 InChI=1S/C22H27NO/c1-16-21-14-18-8-9-19(24)15-20(18)22(16,2)11-13-23(21)12-10-17-6-4-3-5-7-17/h3-9,15-16,21,24H,10-14H2,1-2H3/t16-,21+,22-/m1/s1 ZQHYKVKNPWDQSL-URZJWIJPSA-N 50001043 6,11-Dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL94350 Mu-type opioid receptor Cavia cutleri 0.200000 ChEMBL 10.1016/j.ejmech.2020.112144 10.7270/Q2WM1J54 32087465 Xiong, J; Jin, J; Gao, L; Hao, C; Liu, X; Liu, BF; Chen, Y; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001043&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 49874211 103915576 CHEMBL94350 ZINC13726117 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51475274 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 150 ChEMBL 10.7270/Q22B931S 34995453 Smith, MT; Kong, D; Kuo, A; Imam, MZ; Williams, CM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51475275 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O InChI=1S/C40H50N8O10/c1-23(44-37(55)29(41)18-25-9-13-27(50)14-10-25)36(54)46-30(19-24-6-3-2-4-7-24)38(56)43-21-34(52)45-31(20-26-11-15-28(51)16-12-26)40(58)48-17-5-8-33(48)39(57)47-32(22-49)35(42)53/h2-4,6-7,9-16,23,29-33,49-51H,5,8,17-22,41H2,1H3,(H2,42,53)(H,43,56)(H,44,55)(H,45,52)(H,46,54)(H,47,57)/t23-,29+,30+,31+,32+,33+/m1/s1 FHZPGIUBXYVUOY-VWGYHWLBSA-N 50059841 (S)-1-[(S)-2-[2-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid ((S)-1-carbamoyl-2-hydroxy-ethyl)-amide::(S)-2-Amino-N-{(R)-1-[(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethylcarbamoyl]-ethyl}-3-(4-hydroxy-phenyl)-propionamide::1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide::1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide (Dermorphin)::1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide(Dermorphin)::CHEMBL278789::DERMORPHIN::Dermorphin;1-[2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-acetylamino]-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid (1-carbamoyl-2-hydroxy-ethyl)-amide::H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2::Tyr-Ala-Phe-Gly-Tyr-Pro-Ser::YAFGYPS-NH2 Mu-type opioid receptor Cavia cutleri 1.1 ChEMBL 10.7270/Q22B931S 34995453 Smith, MT; Kong, D; Kuo, A; Imam, MZ; Williams, CM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059841 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059841&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5485199 103955620 CHEMBL278789 ZINC95548678 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51475276 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(N)=O InChI=1S/C37H45N7O8/c1-22(41-35(50)28(38)18-24-9-13-26(45)14-10-24)34(49)43-29(19-23-6-3-2-4-7-23)36(51)40-21-32(47)42-30(20-25-11-15-27(46)16-12-25)37(52)44-17-5-8-31(44)33(39)48/h2-4,6-7,9-16,22,28-31,45-46H,5,8,17-21,38H2,1H3,(H2,39,48)(H,40,51)(H,41,50)(H,42,47)(H,43,49)/t22-,28+,29+,30+,31+/m1/s1 QNPFTWIZSKVYAK-OITLVIEGSA-N 50594831 CHEMBL5185861 Mu-type opioid receptor Cavia cutleri 2.7 ChEMBL 10.7270/Q22B931S 34995453 Smith, MT; Kong, D; Kuo, A; Imam, MZ; Williams, CM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50594831 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50594831&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 14561322 482605683 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51475277 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O InChI=1S/C32H38N6O7/c1-19(36-31(44)25(33)15-21-7-11-23(39)12-8-21)30(43)38-27(17-20-5-3-2-4-6-20)32(45)35-18-28(41)37-26(29(34)42)16-22-9-13-24(40)14-10-22/h2-14,19,25-27,39-40H,15-18,33H2,1H3,(H2,34,42)(H,35,45)(H,36,44)(H,37,41)(H,38,43)/t19-,25+,26+,27+/m1/s1 PUELGZQCDVYIIV-QVKLTZRHSA-N 50594832 CHEMBL5185581 Mu-type opioid receptor Cavia cutleri 2.9 ChEMBL 10.7270/Q22B931S 34995453 Smith, MT; Kong, D; Kuo, A; Imam, MZ; Williams, CM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50594832 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50594832&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10461503 482605684 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51475278 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(O)=O InChI=1S/C23H28N4O6/c1-14(26-22(32)18(24)11-16-7-9-17(28)10-8-16)21(31)27-19(23(33)25-13-20(29)30)12-15-5-3-2-4-6-15/h2-10,14,18-19,28H,11-13,24H2,1H3,(H,25,33)(H,26,32)(H,27,31)(H,29,30)/t14-,18+,19+/m1/s1 CWPDVLMKCHLLPS-CCKFTAQKSA-N 50594833 CHEMBL5196508 Mu-type opioid receptor Cavia cutleri 35 ChEMBL 10.7270/Q22B931S 34995453 Smith, MT; Kong, D; Kuo, A; Imam, MZ; Williams, CM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50594833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50594833&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 132899 482605685 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51475279 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C21H26N4O4/c1-13(24-21(29)17(22)11-15-7-9-16(26)10-8-15)20(28)25-18(19(23)27)12-14-5-3-2-4-6-14/h2-10,13,17-18,26H,11-12,22H2,1H3,(H2,23,27)(H,24,29)(H,25,28)/t13-,17+,18+/m1/s1 LOMBFONOWDRHJW-BVGQSLNGSA-N 50594845 CHEMBL5196824 Mu-type opioid receptor Cavia cutleri 262 ChEMBL 10.7270/Q22B931S 34995453 Smith, MT; Kong, D; Kuo, A; Imam, MZ; Williams, CM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50594845 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50594845&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 7018718 482605697 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51475280 C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C43H57N9O9/c1-26(48-40(58)32(45)22-28-12-16-30(53)17-13-28)39(57)51-34(23-27-8-3-2-4-9-27)41(59)47-25-37(55)49-35(24-29-14-18-31(54)19-15-29)43(61)52-21-7-11-36(52)42(60)50-33(38(46)56)10-5-6-20-44/h2-4,8-9,12-19,26,32-36,53-54H,5-7,10-11,20-25,44-45H2,1H3,(H2,46,56)(H,47,59)(H,48,58)(H,49,55)(H,50,60)(H,51,57)/t26-,32+,33+,34+,35+,36+/m1/s1 OAYQFQPLBIBLJE-NKQYGYANSA-N 50594846 CHEMBL5209004 Mu-type opioid receptor Cavia cutleri 1.7 ChEMBL 10.7270/Q22B931S 34995453 Smith, MT; Kong, D; Kuo, A; Imam, MZ; Williams, CM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50594846 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50594846&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9988107 482605698 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51475281 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O InChI=1S/C43H57N11O10/c44-30(20-26-10-14-28(56)15-11-26)38(60)51-31(8-4-18-48-43(46)47)40(62)52-32(21-25-6-2-1-3-7-25)39(61)49-23-36(58)50-33(22-27-12-16-29(57)17-13-27)42(64)54-19-5-9-35(54)41(63)53-34(24-55)37(45)59/h1-3,6-7,10-17,30-35,55-57H,4-5,8-9,18-24,44H2,(H2,45,59)(H,49,61)(H,50,58)(H,51,60)(H,52,62)(H,53,63)(H4,46,47,48)/t30-,31+,32-,33-,34-,35-/m0/s1 OBRCSEVKVDPXJO-IUCALIBESA-N 50594847 CHEMBL5171778 Mu-type opioid receptor Cavia cutleri 90 ChEMBL 10.7270/Q22B931S 34995453 Smith, MT; Kong, D; Kuo, A; Imam, MZ; Williams, CM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50594847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50594847&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 125954 482605699 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51475282 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(N)=O InChI=1S/C40H52N10O8/c41-29(20-25-10-14-27(51)15-11-25)36(55)48-30(8-4-18-45-40(43)44)38(57)49-31(21-24-6-2-1-3-7-24)37(56)46-23-34(53)47-32(22-26-12-16-28(52)17-13-26)39(58)50-19-5-9-33(50)35(42)54/h1-3,6-7,10-17,29-33,51-52H,4-5,8-9,18-23,41H2,(H2,42,54)(H,46,56)(H,47,53)(H,48,55)(H,49,57)(H4,43,44,45)/t29-,30+,31-,32-,33-/m0/s1 NBYLFTMZRDHRIF-WUXKFAKNSA-N 50594848 CHEMBL5185896 Mu-type opioid receptor Cavia cutleri 190 ChEMBL 10.7270/Q22B931S 34995453 Smith, MT; Kong, D; Kuo, A; Imam, MZ; Williams, CM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50594848 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50594848&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 13686245 482605700 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51475283 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O InChI=1S/C35H45N9O7/c36-26(17-22-8-12-24(45)13-9-22)32(49)43-27(7-4-16-40-35(38)39)34(51)44-29(19-21-5-2-1-3-6-21)33(50)41-20-30(47)42-28(31(37)48)18-23-10-14-25(46)15-11-23/h1-3,5-6,8-15,26-29,45-46H,4,7,16-20,36H2,(H2,37,48)(H,41,50)(H,42,47)(H,43,49)(H,44,51)(H4,38,39,40)/t26-,27+,28-,29-/m0/s1 FKAKFHGIXCCTGS-CRNKYVSFSA-N 50594849 CHEMBL5197191 Mu-type opioid receptor Cavia cutleri 160 ChEMBL 10.7270/Q22B931S 34995453 Smith, MT; Kong, D; Kuo, A; Imam, MZ; Williams, CM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50594849 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50594849&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 13686243 482605701 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51475284 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(O)=O InChI=1S/C26H35N7O6/c27-19(13-17-8-10-18(34)11-9-17)23(37)32-20(7-4-12-30-26(28)29)25(39)33-21(24(38)31-15-22(35)36)14-16-5-2-1-3-6-16/h1-3,5-6,8-11,19-21,34H,4,7,12-15,27H2,(H,31,38)(H,32,37)(H,33,39)(H,35,36)(H4,28,29,30)/t19-,20+,21-/m0/s1 VSJWLOSBQHTHCK-HBMCJLEFSA-N 50594850 CHEMBL5186833 Mu-type opioid receptor Cavia cutleri 11 ChEMBL 10.7270/Q22B931S 34995453 Smith, MT; Kong, D; Kuo, A; Imam, MZ; Williams, CM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50594850 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50594850&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 13476501 482605702 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51475285 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C24H33N7O4/c25-18(13-16-8-10-17(32)11-9-16)22(34)30-19(7-4-12-29-24(27)28)23(35)31-20(21(26)33)14-15-5-2-1-3-6-15/h1-3,5-6,8-11,18-20,32H,4,7,12-14,25H2,(H2,26,33)(H,30,34)(H,31,35)(H4,27,28,29)/t18-,19+,20-/m0/s1 ZMLABQYMRILRFD-ZCNNSNEGSA-N 50594851 CHEMBL5176903 Mu-type opioid receptor Cavia cutleri 240 ChEMBL 10.7270/Q22B931S 34995453 Smith, MT; Kong, D; Kuo, A; Imam, MZ; Williams, CM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50594851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50594851&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 71414822 482605703 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51475286 C[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O InChI=1S/C40H50N8O10/c1-23(44-37(55)29(41)18-25-9-13-27(50)14-10-25)36(54)46-30(19-24-6-3-2-4-7-24)38(56)43-21-34(52)45-31(20-26-11-15-28(51)16-12-26)40(58)48-17-5-8-33(48)39(57)47-32(22-49)35(42)53/h2-4,6-7,9-16,23,29-33,49-51H,5,8,17-22,41H2,1H3,(H2,42,53)(H,43,56)(H,44,55)(H,45,52)(H,46,54)(H,47,57)/t23-,29-,30-,31-,32-,33-/m0/s1 FHZPGIUBXYVUOY-XDGMXVDYSA-N 50142701 CHEMBL285479 Mu-type opioid receptor Cavia cutleri >4000 ChEMBL 10.7270/Q22B931S 34995453 Smith, MT; Kong, D; Kuo, A; Imam, MZ; Williams, CM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50142701 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50142701&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 107772 336952807 CHEMBL285479 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51475287 N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](CCCNC(N)=N)C(N)=O InChI=1S/C15H24N6O3/c16-11(8-9-3-5-10(22)6-4-9)14(24)21-12(13(17)23)2-1-7-20-15(18)19/h3-6,11-12,22H,1-2,7-8,16H2,(H2,17,23)(H,21,24)(H4,18,19,20)/t11-,12+/m0/s1 XSZZXPICHPMPDR-NWDGAFQWSA-N 50594852 CHEMBL5201627 Mu-type opioid receptor Cavia cutleri 44000 ChEMBL 10.7270/Q22B931S 34995453 Smith, MT; Kong, D; Kuo, A; Imam, MZ; Williams, CM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50594852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50594852&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 13561593 482605704 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51475288 NCCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O InChI=1S/C30H45N9O5/c31-15-5-4-9-23(26(33)41)37-29(44)25(18-19-7-2-1-3-8-19)39-28(43)24(10-6-16-36-30(34)35)38-27(42)22(32)17-20-11-13-21(40)14-12-20/h1-3,7-8,11-14,22-25,40H,4-6,9-10,15-18,31-32H2,(H2,33,41)(H,37,44)(H,38,42)(H,39,43)(H4,34,35,36)/t22-,23-,24+,25-/m0/s1 UEVAHGMTRWGMTB-JBXUNAHCSA-N 50016867 (S)-6-Amino-2-((S)-2-{(R)-2-[(S)-2-amino-3-(4-hydroxy-phenyl)-propionylamino]-5-guanidino-pentanoylamino}-3-phenyl-propionylamino)-hexanoic acid amide::6-amino-2-[1-[1-[1-amino-2-(4-hydroxyphenyl)-(1S)-ethylcarboxamido]-4-amino(imino)methylamino-(1R)-butylcarboxamido]-2-phenyl-(1S)-ethylcarboxamido]-(2S)-hexanamide::CHEMBL60444 Mu-type opioid receptor Cavia cutleri 254 ChEMBL 10.7270/Q22B931S 34995453 Smith, MT; Kong, D; Kuo, A; Imam, MZ; Williams, CM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016867&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 122222 103928212 CHEMBL60444 ZINC14951239 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51475289 Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C32H49N9O5/c1-19-15-22(42)16-20(2)23(19)18-24(34)29(44)40-26(12-8-14-38-32(36)37)30(45)41-27(17-21-9-4-3-5-10-21)31(46)39-25(28(35)43)11-6-7-13-33/h3-5,9-10,15-16,24-27,42H,6-8,11-14,17-18,33-34H2,1-2H3,(H2,35,43)(H,39,46)(H,40,44)(H,41,45)(H4,36,37,38)/t24-,25-,26+,27-/m0/s1 FIAKHZXVLBNZLW-NFGXINMFSA-N 50010483 CHEMBL2181202 Mu-type opioid receptor Cavia cutleri 1.4 ChEMBL 10.7270/Q22B931S 34995453 Smith, MT; Kong, D; Kuo, A; Imam, MZ; Williams, CM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010483&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 9809562 242057631 CHEMBL2181202 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51475290 CN(CC(O)=O)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@@H](N)Cc1ccc(O)cc1 InChI=1S/C27H37N7O6/c1-34(16-23(36)37)26(40)22(15-17-6-3-2-4-7-17)33-25(39)21(8-5-13-31-27(29)30)32-24(38)20(28)14-18-9-11-19(35)12-10-18/h2-4,6-7,9-12,20-22,35H,5,8,13-16,28H2,1H3,(H,32,38)(H,33,39)(H,36,37)(H4,29,30,31)/t20-,21+,22-/m0/s1 WASWOPUPHSYARB-BDTNDASRSA-N 50594853 CHEMBL1355638 Mu-type opioid receptor Cavia cutleri 6.9 ChEMBL 10.7270/Q22B931S 34995453 Smith, MT; Kong, D; Kuo, A; Imam, MZ; Williams, CM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50594853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50594853&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 10325393 482605705 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51475371 CC[C@@H]1CN2CC[C@@]3(O)C(Nc4cccc(OC)c34)[C@@H]2C[C@@H]1\C(=C/OC)C(=O)OC InChI=1S/C23H32N2O5/c1-5-14-12-25-10-9-23(27)20-17(7-6-8-19(20)29-3)24-21(23)18(25)11-15(14)16(13-28-2)22(26)30-4/h6-8,13-15,18,21,24,27H,5,9-12H2,1-4H3/b16-13+/t14-,15+,18+,21?,23+/m1/s1 QXFXDJATKPXTFF-GQFFIINBSA-N 50594834 CHEMBL5178409 Mu-type opioid receptor Cavia cutleri 11 ChEMBL 10.7270/Q22B931S 34995453 Smith, MT; Kong, D; Kuo, A; Imam, MZ; Williams, CM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50594834 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50594834&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 138486883 482605686 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51475372 CC[C@@H]1CN2CC[C@@]34OCCO[C@@]3(Nc3ccc(F)c(OC)c43)[C@@H]2C[C@@H]1\C(=C/OC)C(=O)OC InChI=1S/C25H33FN2O6/c1-5-15-13-28-9-8-24-21-19(7-6-18(26)22(21)31-3)27-25(24,34-11-10-33-24)20(28)12-16(15)17(14-30-2)23(29)32-4/h6-7,14-16,20,27H,5,8-13H2,1-4H3/b17-14+/t15-,16+,20+,24+,25+/m1/s1 VDHVQTLHHZZTMJ-GWNIIIPKSA-N 50492099 CHEMBL2396991 Mu-type opioid receptor Cavia cutleri 7.3 ChEMBL 10.7270/Q22B931S 34995453 Smith, MT; Kong, D; Kuo, A; Imam, MZ; Williams, CM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492099 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492099&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 16095099 433959364 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51475373 CC[C@@H]1CN2CC[C@@]3(O)[C@H](Nc4cccc(OC)c34)[C@@H]2C[C@@H]1\C(=C/OC)C(=O)OC InChI=1S/C23H32N2O5/c1-5-14-12-25-10-9-23(27)20-17(7-6-8-19(20)29-3)24-21(23)18(25)11-15(14)16(13-28-2)22(26)30-4/h6-8,13-15,18,21,24,27H,5,9-12H2,1-4H3/b16-13+/t14-,15+,18+,21-,23+/m1/s1 QXFXDJATKPXTFF-LIMHOZKTSA-N 50594867 CHEMBL5187788 Mu-type opioid receptor Cavia cutleri 6.4 ChEMBL 10.7270/Q22B931S 34995453 Smith, MT; Kong, D; Kuo, A; Imam, MZ; Williams, CM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50594867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50594867&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 42629165 482605719 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51475374 CC[C@@H]1CN2CC[C@@]3(O)[C@H](Nc4ccc(F)c(OC)c34)[C@@H]2C[C@@H]1\C(=C/OC)C(=O)OC InChI=1S/C23H31FN2O5/c1-5-13-11-26-9-8-23(28)19-17(7-6-16(24)20(19)30-3)25-21(23)18(26)10-14(13)15(12-29-2)22(27)31-4/h6-7,12-14,18,21,25,28H,5,8-11H2,1-4H3/b15-12+/t13-,14+,18+,21-,23+/m1/s1 DKMVCOVCNPWGTO-CMWCKQEVSA-N 50594868 CHEMBL5178271 Mu-type opioid receptor Cavia cutleri 2.1 ChEMBL 10.7270/Q22B931S 34995453 Smith, MT; Kong, D; Kuo, A; Imam, MZ; Williams, CM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50594868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50594868&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 168277847 482605720 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51497391 CN(C)[C@@H]1C[C@H]2C[C@@H]1N(CC2)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C17H22Cl2N2O/c1-20(2)15-8-12-5-6-21(16(15)9-12)17(22)10-11-3-4-13(18)14(19)7-11/h3-4,7,12,15-16H,5-6,8-10H2,1-2H3/t12-,15+,16-/m0/s1 XVVMBWSNIMBCCY-MAZHCROVSA-N 50603208 CHEMBL5178401 Mu-type opioid receptor Cavia cutleri >1000 ChEMBL 10.7270/Q2XK8KNF 35033825 Jonas, H; Aiello, D; Schepmann, D; Diana, P; Wünsch, B Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50603208 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50603208&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 168277860 482614059 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51497392 Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1 UZHSEJADLWPNLE-GRGSLBFTSA-N 50000788 (morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(naloxone) 4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::(naloxone)4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::(naloxone)4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one (naloxone)::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one( Naloxone)::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(Naxolone)::4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(naloxone)C2H2O4::Analog of 14-(Arylhydroxyamino)codeinone::NALOXONE::NARCAN::SUBOXONE::[17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydroxymorphinan-6-one Mu-type opioid receptor Cavia cutleri 2.3 ChEMBL 10.7270/Q2XK8KNF 35033825 Jonas, H; Aiello, D; Schepmann, D; Diana, P; Wünsch, B Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000788&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search 5284596 103915330 7459 DB01183 1676 C07252 ZINC00389747 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266 51497393 CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 BQJCRHHNABKAKU-KBQPJGBKSA-N 50000092 (-)-(etorphine)::(-)-morphine::(1S,5R,13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(Morphine)::(Morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(morphine) 4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::1N-[2-(5-dimethylaminomethyl-2-furylmethylsulfanyl)ethyl]-1N-methyl-2-nitro-(Z)-1-ethene-1,1-diamine::2-[2-{2-[2-(2-Amino-3-phenyl-propionylamino)-acetylamino]-acetylamino}-3-(4-hydroxy-phenyl)-propionylamino]-4-methylsulfanyl-butyric acid::2-{4-[2,4-diamino-6-pteridinylmethyl(methyl)amino]phenylcarboxamido}pentanedioic acid(morphine)::3-(4-Hydroxy-phenyl)-1-propyl-piperidine-3-carboxylic acid ethyl ester::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ; HydroChloride::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol ;sulphate salt(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol((Morphine))::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine sulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)(HCl)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(morphine)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol,sulfate(Morphinesulfate)::4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diolMorphine::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol (morphine)::4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol(Morphine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Morphine)::6-tert-Butyl-3-methyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine::7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol(morphine)::AMBENYL::AVINZA::Analog of 14-(Arylhydroxyamino)codeinone::BDB50000092::BROMANYL::CHEMBL70::CODRIX::DEPODUR::DIMETANE-DC::INFUMORPH::KADIAN::MORPHINE::MYBANIL::Morphine;4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::TRIACIN-C::US9133125, Table D, morphine Mu-type opioid receptor Cavia cutleri 5.2 ChEMBL 10.7270/Q2XK8KNF 35033825 Jonas, H; Aiello, D; Schepmann, D; Diana, P; Wünsch, B Institut f£r Pharmazeutische und Medizinische Chemie der Universit£t M£nster http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000882&target=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000092&enzyme=Mu-type+opioid+receptor&column=ki&startPg=0&Increment=50&submit=Search MOI 8EF6,1Q0Y,7U62 5288826 103914789 17303 CHEMBL70 DB00295 1627 C01516 ZINC03812983 1 YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI Mu-type opioid receptor OPRM_CAVPO P97266