BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 183287 CN(C)CC1CCc2cc(NC(=O)c3ccc(cc3)-c3ccc(F)cc3)ccc2C1 InChI=1S/C26H27FN2O/c1-29(2)17-18-3-4-23-16-25(14-11-22(23)15-18)28-26(30)21-7-5-19(6-8-21)20-9-12-24(27)13-10-20/h5-14,16,18H,3-4,15,17H2,1-2H3,(H,28,30) GXAQELJVODWLDD-UHFFFAOYSA-N 50150715 4''-Fluoro-biphenyl-4-carboxylic acid (6-dimethylaminomethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-amide::4'-fluoro-biphenyl-4-carboxylic acid (6-dimethylaminomethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-amide::CHEMBL178707::N-(6-((dimethylamino)methyl)-5,6,7,8-tetrahydronaphthalen-2-yl)-4'-fluorobiphenyl-4-carboxamide::T-226296 Melanin-concentrating hormone receptor 1 Rattus 8.6 PDSP Ki 10.1016/s0014-2999(02)01314-6 10.7270/Q2GX495R 11909603 Takekawa, S; Asami, A; Ishihara, Y; Terauchi, J; Kato, K; Shimomura, Y; Mori, M; Murakoshi, H; Kato, K; Suzuki, N; Nishimura, O; Fujino, M Takeda Chemical Industries, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150715 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150715&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 9865843 104039074 CHEMBL178707 1314 ZINC03972273 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50520740 COc1cc(ccc1OCC1(O)CC(F)(F)C1)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C24H19ClF2N2O4S/c1-32-19-8-16(6-7-18(19)33-12-23(31)10-24(26,27)11-23)29-13-28-17-9-20(34-21(17)22(29)30)14-2-4-15(25)5-3-14/h2-9,13,31H,10-12H2,1H3 NCXJWNAKIMMZOC-UHFFFAOYSA-N 50194196 CHEMBL2147472 Melanin-concentrating hormone receptor 1 Rattus 12 ChEMBL 10.1021/acs.jmedchem.6b00676 10.7270/Q2W95C41 27564419 Ahmad, S; Washburn, WN; Hernandez, AS; Bisaha, S; Ngu, K; Wang, W; Pelleymounter, MA; Longhi, D; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Zhang, H; Gemzik, B; Janovitz, EB; Huang, C; Zhang, L; Robl, JA; Murphy, BJ Bristol-Myers Squibb Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50194196 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50194196&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 57988809 104076527 CHEMBL2147472 ZINC36080422 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50068645 CCN(CC)c1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1 InChI=1S/C23H24F3N3O/c1-3-29(4-2)21-13-8-17-15-19(11-12-20(17)28-21)27-22(30)14-7-16-5-9-18(10-6-16)23(24,25)26/h5-6,8-13,15H,3-4,7,14H2,1-2H3,(H,27,30) UQMWZLFAACNVCC-UHFFFAOYSA-N 50193694 CHEMBL425098::N-(2-(diethylamino)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide Melanin-concentrating hormone receptor 1 Rattus 830 ChEMBL 10.1016/j.bmcl.2006.08.006 10.7270/Q2ZC82HP 16919456 Jiang, J; Hoang, M; Young, JR; Chaung, D; Eid, R; Turner, C; Lin, P; Tong, X; Wang, J; Tan, C; Feighner, S; Palyha, O; Hreniuk, DL; Pan, J; Sailer, AW; MacNeil, DJ; Howard, A; Shearman, L; Stribling, S; Camacho, R; Strack, A; Van der Ploeg, LH; Goulet, MT; DeVita, RJ Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193694 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193694&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44417976 104076106 CHEMBL425098 ZINC36351922 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50068649 FC(F)(F)c1ccc(CCC(=O)Nc2ccc3nc(ccc3c2)N2CC3CC2CN3)cc1 InChI=1S/C24H23F3N4O/c25-24(26,27)17-5-1-15(2-6-17)3-10-23(32)29-18-7-8-21-16(11-18)4-9-22(30-21)31-14-19-12-20(31)13-28-19/h1-2,4-9,11,19-20,28H,3,10,12-14H2,(H,29,32) VQQHZQHBXFLNTH-UHFFFAOYSA-N 50193690 CHEMBL386548::N-(2-(2,5-diazabicyclo[2.2.1]heptan-2-yl)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide Melanin-concentrating hormone receptor 1 Rattus 490 ChEMBL 10.1016/j.bmcl.2006.08.006 10.7270/Q2ZC82HP 16919456 Jiang, J; Hoang, M; Young, JR; Chaung, D; Eid, R; Turner, C; Lin, P; Tong, X; Wang, J; Tan, C; Feighner, S; Palyha, O; Hreniuk, DL; Pan, J; Sailer, AW; MacNeil, DJ; Howard, A; Shearman, L; Stribling, S; Camacho, R; Strack, A; Van der Ploeg, LH; Goulet, MT; DeVita, RJ Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193690 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193690&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44417975 104076102 CHEMBL386548 ZINC36351921 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50068654 Nc1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1 InChI=1S/C19H16F3N3O/c20-19(21,22)14-5-1-12(2-6-14)3-10-18(26)24-15-7-8-16-13(11-15)4-9-17(23)25-16/h1-2,4-9,11H,3,10H2,(H2,23,25)(H,24,26) AAOYBQGKRBCNLH-UHFFFAOYSA-N 50193697 CHEMBL217751::N-(2-aminoquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide Melanin-concentrating hormone receptor 1 Rattus 720 ChEMBL 10.1016/j.bmcl.2006.08.006 10.7270/Q2ZC82HP 16919456 Jiang, J; Hoang, M; Young, JR; Chaung, D; Eid, R; Turner, C; Lin, P; Tong, X; Wang, J; Tan, C; Feighner, S; Palyha, O; Hreniuk, DL; Pan, J; Sailer, AW; MacNeil, DJ; Howard, A; Shearman, L; Stribling, S; Camacho, R; Strack, A; Van der Ploeg, LH; Goulet, MT; DeVita, RJ Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193697 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193697&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44417982 104076109 CHEMBL217751 ZINC36351894 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50068659 CN(C1CCCC1)c1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1 InChI=1S/C25H26F3N3O/c1-31(21-4-2-3-5-21)23-14-9-18-16-20(12-13-22(18)30-23)29-24(32)15-8-17-6-10-19(11-7-17)25(26,27)28/h6-7,9-14,16,21H,2-5,8,15H2,1H3,(H,29,32) KBHLPVBYLGCCML-UHFFFAOYSA-N 50193701 CHEMBL215082::N-(2-(cyclopentyl(methyl)amino)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide Melanin-concentrating hormone receptor 1 Rattus 350 ChEMBL 10.1016/j.bmcl.2006.08.006 10.7270/Q2ZC82HP 16919456 Jiang, J; Hoang, M; Young, JR; Chaung, D; Eid, R; Turner, C; Lin, P; Tong, X; Wang, J; Tan, C; Feighner, S; Palyha, O; Hreniuk, DL; Pan, J; Sailer, AW; MacNeil, DJ; Howard, A; Shearman, L; Stribling, S; Camacho, R; Strack, A; Van der Ploeg, LH; Goulet, MT; DeVita, RJ Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193701 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193701&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 22018856 104076113 CHEMBL215082 ZINC36351770 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50068660 CN(C1CCCCC1)c1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1 InChI=1S/C26H28F3N3O/c1-32(22-5-3-2-4-6-22)24-15-10-19-17-21(13-14-23(19)31-24)30-25(33)16-9-18-7-11-20(12-8-18)26(27,28)29/h7-8,10-15,17,22H,2-6,9,16H2,1H3,(H,30,33) JJTLYFUOOPYTDY-UHFFFAOYSA-N 50193682 CHEMBL386046::N-(2-(cyclohexyl(methyl)amino)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide Melanin-concentrating hormone receptor 1 Rattus 1200 ChEMBL 10.1016/j.bmcl.2006.08.006 10.7270/Q2ZC82HP 16919456 Jiang, J; Hoang, M; Young, JR; Chaung, D; Eid, R; Turner, C; Lin, P; Tong, X; Wang, J; Tan, C; Feighner, S; Palyha, O; Hreniuk, DL; Pan, J; Sailer, AW; MacNeil, DJ; Howard, A; Shearman, L; Stribling, S; Camacho, R; Strack, A; Van der Ploeg, LH; Goulet, MT; DeVita, RJ Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193682 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193682&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44417903 104076094 CHEMBL386046 ZINC38145027 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50068661 CNc1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1 InChI=1S/C20H18F3N3O/c1-24-18-10-5-14-12-16(8-9-17(14)26-18)25-19(27)11-4-13-2-6-15(7-3-13)20(21,22)23/h2-3,5-10,12H,4,11H2,1H3,(H,24,26)(H,25,27) VXMXEDWIHDHRKH-UHFFFAOYSA-N 50193695 CHEMBL214541::N-(2-(methylamino)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide Melanin-concentrating hormone receptor 1 Rattus 330 ChEMBL 10.1016/j.bmcl.2006.08.006 10.7270/Q2ZC82HP 16919456 Jiang, J; Hoang, M; Young, JR; Chaung, D; Eid, R; Turner, C; Lin, P; Tong, X; Wang, J; Tan, C; Feighner, S; Palyha, O; Hreniuk, DL; Pan, J; Sailer, AW; MacNeil, DJ; Howard, A; Shearman, L; Stribling, S; Camacho, R; Strack, A; Van der Ploeg, LH; Goulet, MT; DeVita, RJ Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193695 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193695&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44417888 104076107 CHEMBL214541 ZINC36351769 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50068672 FC(F)(F)c1ccc(CCC(=O)Nc2ccc3nc(ccc3c2)N2CCCCCC2)cc1 InChI=1S/C25H26F3N3O/c26-25(27,28)20-9-5-18(6-10-20)7-14-24(32)29-21-11-12-22-19(17-21)8-13-23(30-22)31-15-3-1-2-4-16-31/h5-6,8-13,17H,1-4,7,14-16H2,(H,29,32) SEMAZIYLKBENKU-UHFFFAOYSA-N 50241102 CHEMBL216455::N-(2-(azepan-1-yl)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide Melanin-concentrating hormone receptor 1 Rattus 1800 ChEMBL 10.1016/j.bmcl.2006.08.006 10.7270/Q2ZC82HP 16919456 Jiang, J; Hoang, M; Young, JR; Chaung, D; Eid, R; Turner, C; Lin, P; Tong, X; Wang, J; Tan, C; Feighner, S; Palyha, O; Hreniuk, DL; Pan, J; Sailer, AW; MacNeil, DJ; Howard, A; Shearman, L; Stribling, S; Camacho, R; Strack, A; Van der Ploeg, LH; Goulet, MT; DeVita, RJ Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241102 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241102&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44418009 104098603 CHEMBL216455 ZINC38145030 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50068673 CNC(=O)NC1CCN(C1)c1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1 InChI=1S/C25H26F3N5O2/c1-29-24(35)31-20-12-13-33(15-20)22-10-5-17-14-19(8-9-21(17)32-22)30-23(34)11-4-16-2-6-18(7-3-16)25(26,27)28/h2-3,5-10,14,20H,4,11-13,15H2,1H3,(H,30,34)(H2,29,31,35) ICPOECOBUQHLDO-UHFFFAOYSA-N 50193675 CHEMBL385661::N-(2-(3-(3-methylureido)pyrrolidin-1-yl)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide Melanin-concentrating hormone receptor 1 Rattus 30 ChEMBL 10.1016/j.bmcl.2006.08.006 10.7270/Q2ZC82HP 16919456 Jiang, J; Hoang, M; Young, JR; Chaung, D; Eid, R; Turner, C; Lin, P; Tong, X; Wang, J; Tan, C; Feighner, S; Palyha, O; Hreniuk, DL; Pan, J; Sailer, AW; MacNeil, DJ; Howard, A; Shearman, L; Stribling, S; Camacho, R; Strack, A; Van der Ploeg, LH; Goulet, MT; DeVita, RJ Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193675 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193675&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 22018997 104076087 CHEMBL385661 ZINC36351941 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50068674 CC(=O)NC1CCN(C1)c1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1 InChI=1S/C25H25F3N4O2/c1-16(33)29-21-12-13-32(15-21)23-10-5-18-14-20(8-9-22(18)31-23)30-24(34)11-4-17-2-6-19(7-3-17)25(26,27)28/h2-3,5-10,14,21H,4,11-13,15H2,1H3,(H,29,33)(H,30,34) HAEBQPAGVYKXCG-UHFFFAOYSA-N 50193687 CHEMBL215316::N-(2-(3-acetamidopyrrolidin-1-yl)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide Melanin-concentrating hormone receptor 1 Rattus 440 ChEMBL 10.1016/j.bmcl.2006.08.006 10.7270/Q2ZC82HP 16919456 Jiang, J; Hoang, M; Young, JR; Chaung, D; Eid, R; Turner, C; Lin, P; Tong, X; Wang, J; Tan, C; Feighner, S; Palyha, O; Hreniuk, DL; Pan, J; Sailer, AW; MacNeil, DJ; Howard, A; Shearman, L; Stribling, S; Camacho, R; Strack, A; Van der Ploeg, LH; Goulet, MT; DeVita, RJ Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193687 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193687&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 22018914 104076099 CHEMBL215316 ZINC36351766 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50068675 FC(F)(F)c1ccc(CCC(=O)Nc2ccc3nc(ccc3c2)N2CCCCC2)cc1 InChI=1S/C24H24F3N3O/c25-24(26,27)19-8-4-17(5-9-19)6-13-23(31)28-20-10-11-21-18(16-20)7-12-22(29-21)30-14-2-1-3-15-30/h4-5,7-12,16H,1-3,6,13-15H2,(H,28,31) CNVFIVMZCNRFEZ-UHFFFAOYSA-N 50193699 CHEMBL215662::N-(2-(piperidin-1-yl)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide Melanin-concentrating hormone receptor 1 Rattus 110 ChEMBL 10.1016/j.bmcl.2006.08.006 10.7270/Q2ZC82HP 16919456 Jiang, J; Hoang, M; Young, JR; Chaung, D; Eid, R; Turner, C; Lin, P; Tong, X; Wang, J; Tan, C; Feighner, S; Palyha, O; Hreniuk, DL; Pan, J; Sailer, AW; MacNeil, DJ; Howard, A; Shearman, L; Stribling, S; Camacho, R; Strack, A; Van der Ploeg, LH; Goulet, MT; DeVita, RJ Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193699 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193699&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44417921 104076111 CHEMBL215662 ZINC36351767 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50068680 NC1CCN(C1)c1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1 InChI=1S/C23H23F3N4O/c24-23(25,26)17-5-1-15(2-6-17)3-10-22(31)28-19-7-8-20-16(13-19)4-9-21(29-20)30-12-11-18(27)14-30/h1-2,4-9,13,18H,3,10-12,14,27H2,(H,28,31) NCWVUFUETBHBEA-UHFFFAOYSA-N 50193703 CHEMBL385612::N-(2-(3-aminopyrrolidin-1-yl)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide Melanin-concentrating hormone receptor 1 Rattus 200 ChEMBL 10.1016/j.bmcl.2006.08.006 10.7270/Q2ZC82HP 16919456 Jiang, J; Hoang, M; Young, JR; Chaung, D; Eid, R; Turner, C; Lin, P; Tong, X; Wang, J; Tan, C; Feighner, S; Palyha, O; Hreniuk, DL; Pan, J; Sailer, AW; MacNeil, DJ; Howard, A; Shearman, L; Stribling, S; Camacho, R; Strack, A; Van der Ploeg, LH; Goulet, MT; DeVita, RJ Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193703 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193703&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 22018896 104076115 CHEMBL385612 ZINC36351854 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50068684 CCCN(C)c1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1 InChI=1S/C23H24F3N3O/c1-3-14-29(2)21-12-7-17-15-19(10-11-20(17)28-21)27-22(30)13-6-16-4-8-18(9-5-16)23(24,25)26/h4-5,7-12,15H,3,6,13-14H2,1-2H3,(H,27,30) BSJZAUQNVKQFNB-UHFFFAOYSA-N 50193677 CHEMBL384848::N-(2-(methyl(propyl)amino)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide Melanin-concentrating hormone receptor 1 Rattus 140 ChEMBL 10.1016/j.bmcl.2006.08.006 10.7270/Q2ZC82HP 16919456 Jiang, J; Hoang, M; Young, JR; Chaung, D; Eid, R; Turner, C; Lin, P; Tong, X; Wang, J; Tan, C; Feighner, S; Palyha, O; Hreniuk, DL; Pan, J; Sailer, AW; MacNeil, DJ; Howard, A; Shearman, L; Stribling, S; Camacho, R; Strack, A; Van der Ploeg, LH; Goulet, MT; DeVita, RJ Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193677 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193677&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 22018919 104076089 CHEMBL384848 ZINC36351778 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50068689 CC(C)N(C)c1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1 InChI=1S/C23H24F3N3O/c1-15(2)29(3)21-12-7-17-14-19(10-11-20(17)28-21)27-22(30)13-6-16-4-8-18(9-5-16)23(24,25)26/h4-5,7-12,14-15H,6,13H2,1-3H3,(H,27,30) MPLZJJHETRKHRI-UHFFFAOYSA-N 50193681 CHEMBL215648::N-(2-(isopropyl(methyl)amino)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide Melanin-concentrating hormone receptor 1 Rattus 140 ChEMBL 10.1016/j.bmcl.2006.08.006 10.7270/Q2ZC82HP 16919456 Jiang, J; Hoang, M; Young, JR; Chaung, D; Eid, R; Turner, C; Lin, P; Tong, X; Wang, J; Tan, C; Feighner, S; Palyha, O; Hreniuk, DL; Pan, J; Sailer, AW; MacNeil, DJ; Howard, A; Shearman, L; Stribling, S; Camacho, R; Strack, A; Van der Ploeg, LH; Goulet, MT; DeVita, RJ Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193681 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193681&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 22018999 104076093 CHEMBL215648 ZINC36351779 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50068700 FC(F)(F)c1ccc(CCC(=O)Nc2ccc3nc(ccc3c2)N2CCCC2)cc1 InChI=1S/C23H22F3N3O/c24-23(25,26)18-7-3-16(4-8-18)5-12-22(30)27-19-9-10-20-17(15-19)6-11-21(28-20)29-13-1-2-14-29/h3-4,6-11,15H,1-2,5,12-14H2,(H,27,30) MVQARQYRYGFFIV-UHFFFAOYSA-N 50193676 CHEMBL215331::N-(2-(dimethylamino)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide::N-(2-(pyrrolidin-1-yl)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide Melanin-concentrating hormone receptor 1 Rattus 320 ChEMBL 10.1016/j.bmcl.2006.08.006 10.7270/Q2ZC82HP 16919456 Jiang, J; Hoang, M; Young, JR; Chaung, D; Eid, R; Turner, C; Lin, P; Tong, X; Wang, J; Tan, C; Feighner, S; Palyha, O; Hreniuk, DL; Pan, J; Sailer, AW; MacNeil, DJ; Howard, A; Shearman, L; Stribling, S; Camacho, R; Strack, A; Van der Ploeg, LH; Goulet, MT; DeVita, RJ Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193676 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193676&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10150955 104076088 CHEMBL215331 ZINC34323602 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50068702 FC(F)(F)c1ccc(CCC(=O)Nc2ccc3nc(ccc3c2)N2CC3CC2CO3)cc1 InChI=1S/C24H22F3N3O2/c25-24(26,27)17-5-1-15(2-6-17)3-10-23(31)28-18-7-8-21-16(11-18)4-9-22(29-21)30-13-20-12-19(30)14-32-20/h1-2,4-9,11,19-20H,3,10,12-14H2,(H,28,31) DCTXDZRQZOKNLS-UHFFFAOYSA-N 50193684 CHEMBL384362::N-(2-(2-oxa-5-azabicyclo[2.2.1]heptan-5-yl)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide Melanin-concentrating hormone receptor 1 Rattus 70 ChEMBL 10.1016/j.bmcl.2006.08.006 10.7270/Q2ZC82HP 16919456 Jiang, J; Hoang, M; Young, JR; Chaung, D; Eid, R; Turner, C; Lin, P; Tong, X; Wang, J; Tan, C; Feighner, S; Palyha, O; Hreniuk, DL; Pan, J; Sailer, AW; MacNeil, DJ; Howard, A; Shearman, L; Stribling, S; Camacho, R; Strack, A; Van der Ploeg, LH; Goulet, MT; DeVita, RJ Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193684 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193684&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44417973 104076096 CHEMBL384362 ZINC36351901 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50068710 FC(F)(F)c1ccc(CCCCCCCCCCCCC(=O)Nc2ccc3nc(ccc3c2)[N+]23CCC(CC2)CC3)cc1 InChI=1S/C36H46F3N3O/c37-36(38,39)31-16-13-28(14-17-31)11-9-7-5-3-1-2-4-6-8-10-12-35(43)40-32-18-19-33-30(27-32)15-20-34(41-33)42-24-21-29(22-25-42)23-26-42/h13-20,27,29H,1-12,21-26H2/p+1 DHGGHSPKBKPGOG-UHFFFAOYSA-O 50193678 1-(6-{13-[4-(trifluoromethyl)phenyl]tridecanamido}quinolin-2-yl)-1-azabicyclo[2.2.2]octan-1-ylium::CHEMBL263686 Melanin-concentrating hormone receptor 1 Rattus 25 ChEMBL 10.1016/j.bmcl.2006.08.006 10.7270/Q2ZC82HP 16919456 Jiang, J; Hoang, M; Young, JR; Chaung, D; Eid, R; Turner, C; Lin, P; Tong, X; Wang, J; Tan, C; Feighner, S; Palyha, O; Hreniuk, DL; Pan, J; Sailer, AW; MacNeil, DJ; Howard, A; Shearman, L; Stribling, S; Camacho, R; Strack, A; Van der Ploeg, LH; Goulet, MT; DeVita, RJ Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193678 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193678&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44417956 104076090 CHEMBL263686 ZINC36351917 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50068711 OS(=O)(=O)NC1CCN(C1)c1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1 InChI=1S/C23H23F3N4O4S/c24-23(25,26)17-5-1-15(2-6-17)3-10-22(31)27-18-7-8-20-16(13-18)4-9-21(28-20)30-12-11-19(14-30)29-35(32,33)34/h1-2,4-9,13,19,29H,3,10-12,14H2,(H,27,31)(H,32,33,34) VGOMLVGCPHXARJ-UHFFFAOYSA-N 50193692 1-(6-(3-(4-(trifluoromethyl)phenyl)propanamido)quinolin-2-yl)pyrrolidin-3-ylsulfamic acid::CHEMBL386211 Melanin-concentrating hormone receptor 1 Rattus 50 ChEMBL 10.1016/j.bmcl.2006.08.006 10.7270/Q2ZC82HP 16919456 Jiang, J; Hoang, M; Young, JR; Chaung, D; Eid, R; Turner, C; Lin, P; Tong, X; Wang, J; Tan, C; Feighner, S; Palyha, O; Hreniuk, DL; Pan, J; Sailer, AW; MacNeil, DJ; Howard, A; Shearman, L; Stribling, S; Camacho, R; Strack, A; Van der Ploeg, LH; Goulet, MT; DeVita, RJ Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193692 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193692&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44417945 104076104 CHEMBL386211 C01614 ZINC36351884 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50068712 FC(F)(F)c1ccc(CCC(=O)Nc2ccc3nc(ccc3c2)N2CC3CCC2C3)cc1 InChI=1S/C25H24F3N3O/c26-25(27,28)19-6-1-16(2-7-19)4-12-24(32)29-20-8-10-22-18(14-20)5-11-23(30-22)31-15-17-3-9-21(31)13-17/h1-2,5-8,10-11,14,17,21H,3-4,9,12-13,15H2,(H,29,32) VMYOYPJHFIMQIY-UHFFFAOYSA-N 50193702 CHEMBL217078::N-(2-(2-azabicyclo[2.2.1]heptan-2-yl)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide Melanin-concentrating hormone receptor 1 Rattus 150 ChEMBL 10.1016/j.bmcl.2006.08.006 10.7270/Q2ZC82HP 16919456 Jiang, J; Hoang, M; Young, JR; Chaung, D; Eid, R; Turner, C; Lin, P; Tong, X; Wang, J; Tan, C; Feighner, S; Palyha, O; Hreniuk, DL; Pan, J; Sailer, AW; MacNeil, DJ; Howard, A; Shearman, L; Stribling, S; Camacho, R; Strack, A; Van der Ploeg, LH; Goulet, MT; DeVita, RJ Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193702&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 22018944 104076114 CHEMBL217078 ZINC36351897 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50068715 FC(F)(F)c1ccc(cn1)C(=O)Nc1ccc2nc(ccc2c1)[N+]12CCC(CC1)CC2 InChI=1S/C23H21F3N4O/c24-23(25,26)20-5-1-17(14-27-20)22(31)28-18-3-4-19-16(13-18)2-6-21(29-19)30-10-7-15(8-11-30)9-12-30/h1-6,13-15H,7-12H2/p+1 JELVMLGNGARORH-UHFFFAOYSA-O 50193686 1-{6-[6-(trifluoromethyl)pyridine-3-amido]quinolin-2-yl}-1-azabicyclo[2.2.2]octan-1-ylium::CHEMBL384150 Melanin-concentrating hormone receptor 1 Rattus >10000 ChEMBL 10.1016/j.bmcl.2006.08.006 10.7270/Q2ZC82HP 16919456 Jiang, J; Hoang, M; Young, JR; Chaung, D; Eid, R; Turner, C; Lin, P; Tong, X; Wang, J; Tan, C; Feighner, S; Palyha, O; Hreniuk, DL; Pan, J; Sailer, AW; MacNeil, DJ; Howard, A; Shearman, L; Stribling, S; Camacho, R; Strack, A; Van der Ploeg, LH; Goulet, MT; DeVita, RJ Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193686&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44417978 104076098 CHEMBL384150 ZINC40767032 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50068716 CC1CCCN1c1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1 InChI=1S/C24H24F3N3O/c1-16-3-2-14-30(16)22-12-7-18-15-20(10-11-21(18)29-22)28-23(31)13-6-17-4-8-19(9-5-17)24(25,26)27/h4-5,7-12,15-16H,2-3,6,13-14H2,1H3,(H,28,31) KHHJLWFCLVTIRA-UHFFFAOYSA-N 50193674 CHEMBL214125::N-(2-(2-methylpyrrolidin-1-yl)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide Melanin-concentrating hormone receptor 1 Rattus 270 ChEMBL 10.1016/j.bmcl.2006.08.006 10.7270/Q2ZC82HP 16919456 Jiang, J; Hoang, M; Young, JR; Chaung, D; Eid, R; Turner, C; Lin, P; Tong, X; Wang, J; Tan, C; Feighner, S; Palyha, O; Hreniuk, DL; Pan, J; Sailer, AW; MacNeil, DJ; Howard, A; Shearman, L; Stribling, S; Camacho, R; Strack, A; Van der Ploeg, LH; Goulet, MT; DeVita, RJ Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193674 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193674&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 22018932 104076086 CHEMBL214125 ZINC36351728 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50068725 FC(F)(F)c1ccc(CCC(=O)Nc2ccc3nc(ccc3c2)N2CCC2)cc1 InChI=1S/C22H20F3N3O/c23-22(24,25)17-6-2-15(3-7-17)4-11-21(29)26-18-8-9-19-16(14-18)5-10-20(27-19)28-12-1-13-28/h2-3,5-10,14H,1,4,11-13H2,(H,26,29) KENHPAGHHILAQR-UHFFFAOYSA-N 50193688 CHEMBL217487::N-(2-(azetidin-1-yl)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide Melanin-concentrating hormone receptor 1 Rattus 56 ChEMBL 10.1016/j.bmcl.2006.08.006 10.7270/Q2ZC82HP 16919456 Jiang, J; Hoang, M; Young, JR; Chaung, D; Eid, R; Turner, C; Lin, P; Tong, X; Wang, J; Tan, C; Feighner, S; Palyha, O; Hreniuk, DL; Pan, J; Sailer, AW; MacNeil, DJ; Howard, A; Shearman, L; Stribling, S; Camacho, R; Strack, A; Van der Ploeg, LH; Goulet, MT; DeVita, RJ Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193688 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193688&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44417911 104076100 CHEMBL217487 ZINC36351873 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50068728 FC(F)(F)c1ccc(CCCCCCCCCCCCC(=O)Nc2ccc3nc(ccc3c2)[N+]23CCC(CC2)CC3)cc1 InChI=1S/C36H46F3N3O/c37-36(38,39)31-16-13-28(14-17-31)11-9-7-5-3-1-2-4-6-8-10-12-35(43)40-32-18-19-33-30(27-32)15-20-34(41-33)42-24-21-29(22-25-42)23-26-42/h13-20,27,29H,1-12,21-26H2/p+1 DHGGHSPKBKPGOG-UHFFFAOYSA-O 50193678 1-(6-{13-[4-(trifluoromethyl)phenyl]tridecanamido}quinolin-2-yl)-1-azabicyclo[2.2.2]octan-1-ylium::CHEMBL263686 Melanin-concentrating hormone receptor 1 Rattus 13 ChEMBL 10.1016/j.bmcl.2006.08.006 10.7270/Q2ZC82HP 16919456 Jiang, J; Hoang, M; Young, JR; Chaung, D; Eid, R; Turner, C; Lin, P; Tong, X; Wang, J; Tan, C; Feighner, S; Palyha, O; Hreniuk, DL; Pan, J; Sailer, AW; MacNeil, DJ; Howard, A; Shearman, L; Stribling, S; Camacho, R; Strack, A; Van der Ploeg, LH; Goulet, MT; DeVita, RJ Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193678 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193678&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44417956 104076090 CHEMBL263686 ZINC36351917 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50068735 FC(F)(F)c1ccc(CCC(=O)Nc2ccc3nc(ccc3c2)N2CC3CCC2CC3)cc1 InChI=1S/C26H26F3N3O/c27-26(28,29)20-7-1-17(2-8-20)5-14-25(33)30-21-9-12-23-19(15-21)6-13-24(31-23)32-16-18-3-10-22(32)11-4-18/h1-2,6-9,12-13,15,18,22H,3-5,10-11,14,16H2,(H,30,33) ZAYSVOFFPKLBAE-UHFFFAOYSA-N 50193680 CHEMBL217207::N-(2-(2-azabicyclo[2.2.2]octan-2-yl)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide Melanin-concentrating hormone receptor 1 Rattus 190 ChEMBL 10.1016/j.bmcl.2006.08.006 10.7270/Q2ZC82HP 16919456 Jiang, J; Hoang, M; Young, JR; Chaung, D; Eid, R; Turner, C; Lin, P; Tong, X; Wang, J; Tan, C; Feighner, S; Palyha, O; Hreniuk, DL; Pan, J; Sailer, AW; MacNeil, DJ; Howard, A; Shearman, L; Stribling, S; Camacho, R; Strack, A; Van der Ploeg, LH; Goulet, MT; DeVita, RJ Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193680&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44417930 104076092 CHEMBL217207 ZINC36351878 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50068741 CC1CCN(C1)c1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1 InChI=1S/C24H24F3N3O/c1-16-12-13-30(15-16)22-10-5-18-14-20(8-9-21(18)29-22)28-23(31)11-4-17-2-6-19(7-3-17)24(25,26)27/h2-3,5-10,14,16H,4,11-13,15H2,1H3,(H,28,31) KMKPVJDUSNIAQE-UHFFFAOYSA-N 50193679 CHEMBL385748::N-(2-(3-methylpyrrolidin-1-yl)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide Melanin-concentrating hormone receptor 1 Rattus 400 ChEMBL 10.1016/j.bmcl.2006.08.006 10.7270/Q2ZC82HP 16919456 Jiang, J; Hoang, M; Young, JR; Chaung, D; Eid, R; Turner, C; Lin, P; Tong, X; Wang, J; Tan, C; Feighner, S; Palyha, O; Hreniuk, DL; Pan, J; Sailer, AW; MacNeil, DJ; Howard, A; Shearman, L; Stribling, S; Camacho, R; Strack, A; Van der Ploeg, LH; Goulet, MT; DeVita, RJ Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193679 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193679&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 22018945 104076091 CHEMBL385748 ZINC36351866 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50068760 CC(C)C(=O)NC1CCN(C1)c1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1 InChI=1S/C27H29F3N4O2/c1-17(2)26(36)32-22-13-14-34(16-22)24-11-6-19-15-21(9-10-23(19)33-24)31-25(35)12-5-18-3-7-20(8-4-18)27(28,29)30/h3-4,6-11,15,17,22H,5,12-14,16H2,1-2H3,(H,31,35)(H,32,36) YIMNCYNDKLUSBQ-UHFFFAOYSA-N 50193696 CHEMBL385452::N-(2-(3-isobutyramidopyrrolidin-1-yl)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide Melanin-concentrating hormone receptor 1 Rattus 90 ChEMBL 10.1016/j.bmcl.2006.08.006 10.7270/Q2ZC82HP 16919456 Jiang, J; Hoang, M; Young, JR; Chaung, D; Eid, R; Turner, C; Lin, P; Tong, X; Wang, J; Tan, C; Feighner, S; Palyha, O; Hreniuk, DL; Pan, J; Sailer, AW; MacNeil, DJ; Howard, A; Shearman, L; Stribling, S; Camacho, R; Strack, A; Van der Ploeg, LH; Goulet, MT; DeVita, RJ Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193696 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193696&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 22018964 104076108 CHEMBL385452 ZINC36351756 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50068768 FC(F)(F)c1ccc(CCC(=O)Nc2ccc3nc(ccc3c2)N2CCC(C2)c2ccccc2)cc1 InChI=1S/C29H26F3N3O/c30-29(31,32)24-10-6-20(7-11-24)8-15-28(36)33-25-12-13-26-22(18-25)9-14-27(34-26)35-17-16-23(19-35)21-4-2-1-3-5-21/h1-7,9-14,18,23H,8,15-17,19H2,(H,33,36) BYTPBLLHHBOSEQ-UHFFFAOYSA-N 50193691 CHEMBL216576::N-(2-(3-phenylpyrrolidin-1-yl)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide Melanin-concentrating hormone receptor 1 Rattus 1770 ChEMBL 10.1016/j.bmcl.2006.08.006 10.7270/Q2ZC82HP 16919456 Jiang, J; Hoang, M; Young, JR; Chaung, D; Eid, R; Turner, C; Lin, P; Tong, X; Wang, J; Tan, C; Feighner, S; Palyha, O; Hreniuk, DL; Pan, J; Sailer, AW; MacNeil, DJ; Howard, A; Shearman, L; Stribling, S; Camacho, R; Strack, A; Van der Ploeg, LH; Goulet, MT; DeVita, RJ Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193691 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193691&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44417917 104076103 CHEMBL216576 ZINC36351852 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50068772 COC(=O)C1CCCN1c1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1 InChI=1S/C25H24F3N3O3/c1-34-24(33)21-3-2-14-31(21)22-12-7-17-15-19(10-11-20(17)30-22)29-23(32)13-6-16-4-8-18(9-5-16)25(26,27)28/h4-5,7-12,15,21H,2-3,6,13-14H2,1H3,(H,29,32) XNPILZWANOBMQM-UHFFFAOYSA-N 50193683 CHEMBL383884::methyl 1-(6-(3-(4-(trifluoromethyl)phenyl)propanamido)quinolin-2-yl)pyrrolidine-2-carboxylate Melanin-concentrating hormone receptor 1 Rattus 580 ChEMBL 10.1016/j.bmcl.2006.08.006 10.7270/Q2ZC82HP 16919456 Jiang, J; Hoang, M; Young, JR; Chaung, D; Eid, R; Turner, C; Lin, P; Tong, X; Wang, J; Tan, C; Feighner, S; Palyha, O; Hreniuk, DL; Pan, J; Sailer, AW; MacNeil, DJ; Howard, A; Shearman, L; Stribling, S; Camacho, R; Strack, A; Van der Ploeg, LH; Goulet, MT; DeVita, RJ Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193683&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44417915 104076095 CHEMBL383884 ZINC36351868 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50068774 FC(F)(F)c1ccc(CCC(=O)Nc2ccc3nc(ccc3c2)N2CCC(C2)NC(=O)c2ccccc2)cc1 InChI=1S/C30H27F3N4O2/c31-30(32,33)23-10-6-20(7-11-23)8-15-28(38)34-24-12-13-26-22(18-24)9-14-27(36-26)37-17-16-25(19-37)35-29(39)21-4-2-1-3-5-21/h1-7,9-14,18,25H,8,15-17,19H2,(H,34,38)(H,35,39) WVAQXTJPENWXAK-UHFFFAOYSA-N 50193685 CHEMBL215981::N-(1-(6-(3-(4-(trifluoromethyl)phenyl)propanamido)quinolin-2-yl)pyrrolidin-3-yl)benzamide Melanin-concentrating hormone receptor 1 Rattus 110 ChEMBL 10.1016/j.bmcl.2006.08.006 10.7270/Q2ZC82HP 16919456 Jiang, J; Hoang, M; Young, JR; Chaung, D; Eid, R; Turner, C; Lin, P; Tong, X; Wang, J; Tan, C; Feighner, S; Palyha, O; Hreniuk, DL; Pan, J; Sailer, AW; MacNeil, DJ; Howard, A; Shearman, L; Stribling, S; Camacho, R; Strack, A; Van der Ploeg, LH; Goulet, MT; DeVita, RJ Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193685 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193685&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44417925 104076097 CHEMBL215981 ZINC36351752 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50068776 CN(C)c1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1 InChI=1S/C21H20F3N3O/c1-27(2)19-11-6-15-13-17(9-10-18(15)26-19)25-20(28)12-5-14-3-7-16(8-4-14)21(22,23)24/h3-4,6-11,13H,5,12H2,1-2H3,(H,25,28) QCKPBMHWCHELBM-UHFFFAOYSA-N 50193689 CHEMBL214984::N-(2-(dimethylamino)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide Melanin-concentrating hormone receptor 1 Rattus 110 ChEMBL 10.1016/j.bmcl.2006.08.006 10.7270/Q2ZC82HP 16919456 Jiang, J; Hoang, M; Young, JR; Chaung, D; Eid, R; Turner, C; Lin, P; Tong, X; Wang, J; Tan, C; Feighner, S; Palyha, O; Hreniuk, DL; Pan, J; Sailer, AW; MacNeil, DJ; Howard, A; Shearman, L; Stribling, S; Camacho, R; Strack, A; Van der Ploeg, LH; Goulet, MT; DeVita, RJ Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193689 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193689&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44417894 104076101 CHEMBL214984 ZINC36351759 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50068789 FC(F)(F)c1ccc(CCC(=O)Nc2ccc3nc(ccc3c2)N2CCC3(CCNC3)C2)cc1 InChI=1S/C26H27F3N4O/c27-26(28,29)20-5-1-18(2-6-20)3-10-24(34)31-21-7-8-22-19(15-21)4-9-23(32-22)33-14-12-25(17-33)11-13-30-16-25/h1-2,4-9,15,30H,3,10-14,16-17H2,(H,31,34) APRWXACNSKEQER-UHFFFAOYSA-N 50193700 CHEMBL217502::N-(2-(2,7-diazaspiro[4.4]nonan-2-yl)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide Melanin-concentrating hormone receptor 1 Rattus 140 ChEMBL 10.1016/j.bmcl.2006.08.006 10.7270/Q2ZC82HP 16919456 Jiang, J; Hoang, M; Young, JR; Chaung, D; Eid, R; Turner, C; Lin, P; Tong, X; Wang, J; Tan, C; Feighner, S; Palyha, O; Hreniuk, DL; Pan, J; Sailer, AW; MacNeil, DJ; Howard, A; Shearman, L; Stribling, S; Camacho, R; Strack, A; Van der Ploeg, LH; Goulet, MT; DeVita, RJ Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193700 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193700&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 22018957 104076112 CHEMBL217502 ZINC36351937 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50290948 Clc1ccc(cc1)-c1ccc(CNC2CCN(CC(c3ccccc3)c3ccccc3)C2)o1 InChI=1S/C29H29ClN2O/c30-25-13-11-24(12-14-25)29-16-15-27(33-29)19-31-26-17-18-32(20-26)21-28(22-7-3-1-4-8-22)23-9-5-2-6-10-23/h1-16,26,28,31H,17-21H2 ATGOCSGYJZJMMY-UHFFFAOYSA-N 50158495 CHEMBL224943::[5-(4-chlorophenyl)furan-2-ylmethyl][1-(2,2-diphenylethyl)pyrrolidin-3-yl]amine Melanin-concentrating hormone receptor 1 Rattus 1700 ChEMBL 10.1021/jm040084c 10.7270/Q2280737 15615535 Lavrador, K; Murphy, B; Saunders, J; Struthers, S; Wang, X; Williams, J Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158495&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11445353 104045228 CHEMBL224943 ZINC22932297 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50290949 O=C(CCCc1ccccc1)NC[C@H]1CCCN1CCc1ccccc1 InChI=1S/C23H30N2O/c26-23(15-7-13-20-9-3-1-4-10-20)24-19-22-14-8-17-25(22)18-16-21-11-5-2-6-12-21/h1-6,9-12,22H,7-8,13-19H2,(H,24,26)/t22-/m1/s1 HFTIKXYSNDRVRI-JOCHJYFZSA-N 50158496 (R)-N-(1-phenethylpyrrolidin-2-ylmethyl)-4-phenylbutyramide::(S)-N-(1-phenethylpyrrolidin-2-ylmethyl)-4-phenylbutyramide::CHEMBL224438 Melanin-concentrating hormone receptor 1 Rattus 3100 ChEMBL 10.1021/jm040084c 10.7270/Q2280737 15615535 Lavrador, K; Murphy, B; Saunders, J; Struthers, S; Wang, X; Williams, J Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158496 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158496&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11385742 104045229 CHEMBL224438 ZINC13586767 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50290950 COCC1=C([C@@H](N(C(=O)NCCCN2CCC(CC2)c2cccc(NC(C)=O)c2)C(=O)N1)c1ccc(F)c(F)c1)C(=O)OC InChI=1S/C31H37F2N5O6/c1-19(39)35-23-7-4-6-21(16-23)20-10-14-37(15-11-20)13-5-12-34-30(41)38-28(22-8-9-24(32)25(33)17-22)27(29(40)44-3)26(18-43-2)36-31(38)42/h4,6-9,16-17,20,28H,5,10-15,18H2,1-3H3,(H,34,41)(H,35,39)(H,36,42)/t28-/m0/s1 FWMHZWMPUWAUPL-NDEPHWFRSA-N 50152456 (S)-3-{3-[4-(3-Acetylamino-phenyl)-piperidin-1-yl]-propylcarbamoyl}-4-(3,4-difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester::(S)-methyl 1-((3-(4-(3-acetamidophenyl)piperidin-1-yl)propyl)carbamoyl)-6-(3,4-difluorophenyl)-4-(methoxymethyl)-2-oxo-1,2,3,6-tetrahydropyrimidine-5-carboxylate::CHEMBL185271 Melanin-concentrating hormone receptor 1 Rattus 2 ChEMBL 10.1021/jm040084c 10.7270/Q2280737 15615535 Lavrador, K; Murphy, B; Saunders, J; Struthers, S; Wang, X; Williams, J Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152456&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11520239 104040521 CHEMBL185271 ZINC03966030 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50290951 Clc1ccc(CN2CCC(C2)NC(=O)Cc2csc3ccccc23)cc1Cl InChI=1S/C21H20Cl2N2OS/c22-18-6-5-14(9-19(18)23)11-25-8-7-16(12-25)24-21(26)10-15-13-27-20-4-2-1-3-17(15)20/h1-6,9,13,16H,7-8,10-12H2,(H,24,26) OJILXUXJQHORBV-UHFFFAOYSA-N 50158497 2-benzo[b]thiophen-3-yl-N-[1-(3,4-dichlorobenzyl)pyrrolidin-3-yl]acetamide::CHEMBL388298 Melanin-concentrating hormone receptor 1 Rattus 360 ChEMBL 10.1021/jm040084c 10.7270/Q2280737 15615535 Lavrador, K; Murphy, B; Saunders, J; Struthers, S; Wang, X; Williams, J Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158497 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158497&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11353108 104045230 CHEMBL388298 ZINC13586760 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50290952 Clc1ccc(CN2CCC(C2)NC(=O)Cc2ccc3OCOc3c2)cc1Cl InChI=1S/C20H20Cl2N2O3/c21-16-3-1-14(7-17(16)22)10-24-6-5-15(11-24)23-20(25)9-13-2-4-18-19(8-13)27-12-26-18/h1-4,7-8,15H,5-6,9-12H2,(H,23,25) DFZNXCBJEKLXMV-UHFFFAOYSA-N 50158498 2-benzo[1,3]dioxol-5-yl-N-[1-(3,4-dichlorobenzyl)pyrrolidin-3-yl]acetamide::CHEMBL390377 Melanin-concentrating hormone receptor 1 Rattus 630 ChEMBL 10.1021/jm040084c 10.7270/Q2280737 15615535 Lavrador, K; Murphy, B; Saunders, J; Struthers, S; Wang, X; Williams, J Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158498 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158498&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11489282 104045231 CHEMBL390377 ZINC13586758 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50290953 CC(CCN1CCC(C1)NCc1ccc(o1)-c1ccc(Cl)cc1)CC(C)(C)C InChI=1S/C24H35ClN2O/c1-18(15-24(2,3)4)11-13-27-14-12-21(17-27)26-16-22-9-10-23(28-22)19-5-7-20(25)8-6-19/h5-10,18,21,26H,11-17H2,1-4H3 HVSUVGONQPOCEW-UHFFFAOYSA-N 50158499 CHEMBL225073::[5-(4-chlorophenyl)-furan-2-ylmethyl][1-(3,5,5-trimethylhexyl)pyrrolidin-3-yl]amine Melanin-concentrating hormone receptor 1 Rattus 5000 ChEMBL 10.1021/jm040084c 10.7270/Q2280737 15615535 Lavrador, K; Murphy, B; Saunders, J; Struthers, S; Wang, X; Williams, J Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158499 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158499&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11273638 104045232 CHEMBL225073 ZINC36351944 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50290954 Clc1ccc(CN2CCC(C2)NC(=O)CCc2ccccc2)cc1Cl InChI=1S/C20H22Cl2N2O/c21-18-8-6-16(12-19(18)22)13-24-11-10-17(14-24)23-20(25)9-7-15-4-2-1-3-5-15/h1-6,8,12,17H,7,9-11,13-14H2,(H,23,25) OFIKKUMQKPOBHQ-UHFFFAOYSA-N 50158500 CHEMBL224219::N-(1-(3,4-dichlorobenzyl)pyrrolidin-3-yl)-3-phenylpropanamide Melanin-concentrating hormone receptor 1 Rattus >10000 ChEMBL 10.1021/jm040084c 10.7270/Q2280737 15615535 Lavrador, K; Murphy, B; Saunders, J; Struthers, S; Wang, X; Williams, J Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158500 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158500&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11268912 104045233 CHEMBL224219 ZINC13586754 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50290955 Clc1ccc(CN2CCC(C2)NC(=O)Cc2ccc(Oc3ccccc3)cc2)cc1Cl InChI=1S/C25H24Cl2N2O2/c26-23-11-8-19(14-24(23)27)16-29-13-12-20(17-29)28-25(30)15-18-6-9-22(10-7-18)31-21-4-2-1-3-5-21/h1-11,14,20H,12-13,15-17H2,(H,28,30) NWNGSBUSKJXPGS-UHFFFAOYSA-N 50158501 CHEMBL224686::N-[1-(3,4-dichlorobenzyl)pyrrolidin-3-yl]-2-(4-phenoxyphenyl)acetamide Melanin-concentrating hormone receptor 1 Rattus 510 ChEMBL 10.1021/jm040084c 10.7270/Q2280737 15615535 Lavrador, K; Murphy, B; Saunders, J; Struthers, S; Wang, X; Williams, J Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158501 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158501&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11342100 104045234 CHEMBL224686 ZINC13586756 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50290957 Clc1ccc(CN2CCC[C@@H]2CNC(=O)Cc2csc3ccccc23)cc1Cl InChI=1S/C22H22Cl2N2OS/c23-19-8-7-15(10-20(19)24)13-26-9-3-4-17(26)12-25-22(27)11-16-14-28-21-6-2-1-5-18(16)21/h1-2,5-8,10,14,17H,3-4,9,11-13H2,(H,25,27)/t17-/m1/s1 ZGXXRCHPJRBHFM-QGZVFWFLSA-N 50158494 (R)-2-benzo[b]thiophen-3-yl-N-[1-(3,4-dichlorobenzyl)-pyrrolidin-2-ylmethyl]acetamide::(S)-2-benzo[b]thiophen-3-yl-N-[1-(3,4-dichloro-benzyl)-pyrrolidin-2-ylmethyl] -acetamide::CHEMBL375291 Melanin-concentrating hormone receptor 1 Rattus 9800 ChEMBL 10.1021/jm040084c 10.7270/Q2280737 15615535 Lavrador, K; Murphy, B; Saunders, J; Struthers, S; Wang, X; Williams, J Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158494 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158494&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11192042 104045227 CHEMBL375291 ZINC13586765 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50290958 Clc1ccc(CN2CCC(C2)NC(=O)Cc2ccccc2)cc1Cl InChI=1S/C19H20Cl2N2O/c20-17-7-6-15(10-18(17)21)12-23-9-8-16(13-23)22-19(24)11-14-4-2-1-3-5-14/h1-7,10,16H,8-9,11-13H2,(H,22,24) HIRYXRSGVDWVGH-UHFFFAOYSA-N 50158502 CHEMBL224519::N-[1-(3,4-dichlorobenzyl)pyrrolidin-3-yl]-2-phenylacetamide Melanin-concentrating hormone receptor 1 Rattus 980 ChEMBL 10.1021/jm040084c 10.7270/Q2280737 15615535 Lavrador, K; Murphy, B; Saunders, J; Struthers, S; Wang, X; Williams, J Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158502 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158502&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11202371 104045235 CHEMBL224519 ZINC13586752 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50290959 O=C(Cc1ccccc1)NC1CCN(CCc2ccccc2)C1 InChI=1S/C20H24N2O/c23-20(15-18-9-5-2-6-10-18)21-19-12-14-22(16-19)13-11-17-7-3-1-4-8-17/h1-10,19H,11-16H2,(H,21,23) JMTJDERCCHJQLI-UHFFFAOYSA-N 50158503 CHEMBL224518::N-(1-phenethylpyrrolidin-3-yl)-2-phenylacetamide Melanin-concentrating hormone receptor 1 Rattus >10000 ChEMBL 10.1021/jm040084c 10.7270/Q2280737 15615535 Lavrador, K; Murphy, B; Saunders, J; Struthers, S; Wang, X; Williams, J Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158503 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158503&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11293118 104045236 CHEMBL224518 ZINC13586750 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50290960 O=C(Cc1ccccc1)NC1CCN(Cc2ccccc2)C1 InChI=1S/C19H22N2O/c22-19(13-16-7-3-1-4-8-16)20-18-11-12-21(15-18)14-17-9-5-2-6-10-17/h1-10,18H,11-15H2,(H,20,22) HMWGXCXCANZRTB-UHFFFAOYSA-N 50158504 CHEMBL387725::N-(1-benzylpyrrolidin-3-yl)-2-phenylacetamide Melanin-concentrating hormone receptor 1 Rattus >10000 ChEMBL 10.1021/jm040084c 10.7270/Q2280737 15615535 Lavrador, K; Murphy, B; Saunders, J; Struthers, S; Wang, X; Williams, J Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158504 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158504&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11269801 104045237 CHEMBL387725 ZINC13586748 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50350796 CN[C@H]1CCN(C1)c1ccc(cn1)-n1ncc2cc(ccc2c1=O)-c1ccc(OC)cc1C InChI=1S/C26H27N5O2/c1-17-12-22(33-3)6-8-23(17)18-4-7-24-19(13-18)14-29-31(26(24)32)21-5-9-25(28-15-21)30-11-10-20(16-30)27-2/h4-9,12-15,20,27H,10-11,16H2,1-3H3/t20-/m0/s1 HCVLQMDNMILQJN-FQEVSTJZSA-N 50189577 6-(4-methoxy-2-methylphenyl)-2-(6-((S)-3-(methylamino)pyrrolidin-1-yl)pyridin-3-yl)phthalazin-1(2H)-one::CHEMBL208551 Melanin-concentrating hormone receptor 1 Rattus 11 ChEMBL 10.1021/jm051263c 10.7270/Q2Z037SN 16789729 Dyck, B; Markison, S; Zhao, L; Tamiya, J; Grey, J; Rowbottom, MW; Zhang, M; Vickers, T; Sorensen, K; Norton, C; Wen, J; Heise, CE; Saunders, J; Conlon, P; Madan, A; Schwarz, D; Goodfellow, VS Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189577&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11546697 104073098 CHEMBL208551 ZINC34661962 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50350797 CN[C@@H]1CCN(C1)c1ccc(cn1)-n1ncc2cc(sc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C22H20ClN5OS/c1-24-17-8-9-27(13-17)20-7-6-18(12-25-20)28-22(29)21-15(11-26-28)10-19(30-21)14-2-4-16(23)5-3-14/h2-7,10-12,17,24H,8-9,13H2,1H3/t17-/m1/s1 WKUKSXXIRVSPSN-QGZVFWFLSA-N 50189578 (R)-2-(4-chlorophenyl)-6-(6-(3-(methylamino)pyrrolidin-1-yl)pyridin-3-yl)thieno[2,3-d]pyridazin-7(6H)-one::CHEMBL377588 Melanin-concentrating hormone receptor 1 Rattus 1.9 ChEMBL 10.1021/jm051263c 10.7270/Q2Z037SN 16789729 Dyck, B; Markison, S; Zhao, L; Tamiya, J; Grey, J; Rowbottom, MW; Zhang, M; Vickers, T; Sorensen, K; Norton, C; Wen, J; Heise, CE; Saunders, J; Conlon, P; Madan, A; Schwarz, D; Goodfellow, VS Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189578&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11532214 104073099 CHEMBL377588 ZINC36351524 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50350798 CCN[C@H]1CCN(C1)c1ccc(cn1)-n1ncc2cc(ccc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C25H24ClN5O/c1-2-27-21-11-12-30(16-21)24-10-8-22(15-28-24)31-25(32)23-9-5-18(13-19(23)14-29-31)17-3-6-20(26)7-4-17/h3-10,13-15,21,27H,2,11-12,16H2,1H3/t21-/m0/s1 LBZHIWFHKQIDAE-NRFANRHFSA-N 50189579 (S)-6-(4-chlorophenyl)-2-(6-(3-(ethylamino)pyrrolidin-1-yl)pyridin-3-yl)phthalazin-1(2H)-one::CHEMBL209172 Melanin-concentrating hormone receptor 1 Rattus 1.9 ChEMBL 10.1021/jm051263c 10.7270/Q2Z037SN 16789729 Dyck, B; Markison, S; Zhao, L; Tamiya, J; Grey, J; Rowbottom, MW; Zhang, M; Vickers, T; Sorensen, K; Norton, C; Wen, J; Heise, CE; Saunders, J; Conlon, P; Madan, A; Schwarz, D; Goodfellow, VS Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189579 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189579&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11612046 104073100 CHEMBL209172 ZINC35934563 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50350799 CN(C)[C@H]1CCN(C1)c1ccc(cn1)-n1ncc2cc(oc2c1=O)-c1ccc(cc1)C(F)(F)F InChI=1S/C24H22F3N5O2/c1-30(2)19-9-10-31(14-19)21-8-7-18(13-28-21)32-23(33)22-16(12-29-32)11-20(34-22)15-3-5-17(6-4-15)24(25,26)27/h3-8,11-13,19H,9-10,14H2,1-2H3/t19-/m0/s1 LCLZDLHNBUWRJC-IBGZPJMESA-N 50189580 (S)-6-(6-(3-(dimethylamino)pyrrolidin-1-yl)pyridin-3-yl)-2-(4-(trifluoromethyl)phenyl)furo[2,3-d]pyridazin-7(6H)-one::CHEMBL379927 Melanin-concentrating hormone receptor 1 Rattus 21 ChEMBL 10.1021/jm051263c 10.7270/Q2Z037SN 16789729 Dyck, B; Markison, S; Zhao, L; Tamiya, J; Grey, J; Rowbottom, MW; Zhang, M; Vickers, T; Sorensen, K; Norton, C; Wen, J; Heise, CE; Saunders, J; Conlon, P; Madan, A; Schwarz, D; Goodfellow, VS Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189580 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189580&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11612491 104073101 CHEMBL379927 ZINC35935526 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50350800 CN[C@H]1CCN(C1)c1ccc(cn1)-n1ncc2cc(ccc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C24H22ClN5O/c1-26-20-10-11-29(15-20)23-9-7-21(14-27-23)30-24(31)22-8-4-17(12-18(22)13-28-30)16-2-5-19(25)6-3-16/h2-9,12-14,20,26H,10-11,15H2,1H3/t20-/m0/s1 DAVBMFYLYDYHHC-FQEVSTJZSA-N 50189581 (S)-6-(4-chlorophenyl)-2-(6-(3-(methylamino)pyrrolidin-1-yl)pyridin-3-yl)phthalazin-1(2H)-one::CHEMBL210191 Melanin-concentrating hormone receptor 1 Rattus 8.5 ChEMBL 10.1021/jm051263c 10.7270/Q2Z037SN 16789729 Dyck, B; Markison, S; Zhao, L; Tamiya, J; Grey, J; Rowbottom, MW; Zhang, M; Vickers, T; Sorensen, K; Norton, C; Wen, J; Heise, CE; Saunders, J; Conlon, P; Madan, A; Schwarz, D; Goodfellow, VS Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189581 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189581&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11582824 104073102 CHEMBL210191 ZINC35861370 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50350801 Clc1ccc(cc1)-c1ccc2c(cnn(-c3ccc(nc3)N3CC[C@@H](C3)NN3CCCC3)c2=O)c1 InChI=1S/C27H27ClN6O/c28-22-6-3-19(4-7-22)20-5-9-25-21(15-20)16-30-34(27(25)35)24-8-10-26(29-17-24)32-14-11-23(18-32)31-33-12-1-2-13-33/h3-10,15-17,23,31H,1-2,11-14,18H2/t23-/m0/s1 KCUDWRRMPLPHLB-QHCPKHFHSA-N 50189582 (S)-6-(4-chlorophenyl)-2-(6-(3-(pyrrolidin-1-ylamino)pyrrolidin-1-yl)pyridin-3-yl)phthalazin-1(2H)-one::CHEMBL212053 Melanin-concentrating hormone receptor 1 Rattus 1.6 ChEMBL 10.1021/jm051263c 10.7270/Q2Z037SN 16789729 Dyck, B; Markison, S; Zhao, L; Tamiya, J; Grey, J; Rowbottom, MW; Zhang, M; Vickers, T; Sorensen, K; Norton, C; Wen, J; Heise, CE; Saunders, J; Conlon, P; Madan, A; Schwarz, D; Goodfellow, VS Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189582 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189582&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44413240 104073103 CHEMBL212053 ZINC36351523 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50350802 CN(C)[C@H]1CCN(C1)c1ccc(cn1)-n1ncc2cc(sc2c1=O)-c1ccc(cc1)C(F)(F)F InChI=1S/C24H22F3N5OS/c1-30(2)19-9-10-31(14-19)21-8-7-18(13-28-21)32-23(33)22-16(12-29-32)11-20(34-22)15-3-5-17(6-4-15)24(25,26)27/h3-8,11-13,19H,9-10,14H2,1-2H3/t19-/m0/s1 ZJHQVUWPGYYYDW-IBGZPJMESA-N 50189583 (S)-6-(6-(3-(dimethylamino)pyrrolidin-1-yl)pyridin-3-yl)-2-(4-(trifluoromethyl)phenyl)thieno[2,3-d]pyridazin-7(6H)-one::CHEMBL208845 Melanin-concentrating hormone receptor 1 Rattus 4.4 ChEMBL 10.1021/jm051263c 10.7270/Q2Z037SN 16789729 Dyck, B; Markison, S; Zhao, L; Tamiya, J; Grey, J; Rowbottom, MW; Zhang, M; Vickers, T; Sorensen, K; Norton, C; Wen, J; Heise, CE; Saunders, J; Conlon, P; Madan, A; Schwarz, D; Goodfellow, VS Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189583 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189583&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11684498 104073104 CHEMBL208845 ZINC36351522 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50350803 CN[C@@H]1CCN(C1)c1ccc(cn1)-n1ncc2cc(sc2c1=O)-c1ccc(cc1)C(F)(F)F InChI=1S/C23H20F3N5OS/c1-27-17-8-9-30(13-17)20-7-6-18(12-28-20)31-22(32)21-15(11-29-31)10-19(33-21)14-2-4-16(5-3-14)23(24,25)26/h2-7,10-12,17,27H,8-9,13H2,1H3/t17-/m1/s1 VKAMBSPXFFZIQB-QGZVFWFLSA-N 50189576 (R)-6-(6-(3-(methylamino)pyrrolidin-1-yl)pyridin-3-yl)-2-(4-(trifluoromethyl)phenyl)thieno[2,3-d]pyridazin-7(6H)-one::CHEMBL377241 Melanin-concentrating hormone receptor 1 Rattus 7.7 ChEMBL 10.1021/jm051263c 10.7270/Q2Z037SN 16789729 Dyck, B; Markison, S; Zhao, L; Tamiya, J; Grey, J; Rowbottom, MW; Zhang, M; Vickers, T; Sorensen, K; Norton, C; Wen, J; Heise, CE; Saunders, J; Conlon, P; Madan, A; Schwarz, D; Goodfellow, VS Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189576&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11532924 104073097 CHEMBL377241 ZINC34802297 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50350804 CN(C)[C@@H]1CCN(C1)c1ccc(cn1)-n1ncc2cc(ccc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C25H24ClN5O/c1-29(2)22-11-12-30(16-22)24-10-8-21(15-27-24)31-25(32)23-9-5-18(13-19(23)14-28-31)17-3-6-20(26)7-4-17/h3-10,13-15,22H,11-12,16H2,1-2H3/t22-/m1/s1 LQVKFCWAMKNRJH-JOCHJYFZSA-N 50189584 (R)-6-(4-chlorophenyl)-2-(6-(3-(dimethylamino)pyrrolidin-1-yl)pyridin-3-yl)phthalazin-1(2H)-one::CHEMBL379189 Melanin-concentrating hormone receptor 1 Rattus 1.1 ChEMBL 10.1021/jm051263c 10.7270/Q2Z037SN 16789729 Dyck, B; Markison, S; Zhao, L; Tamiya, J; Grey, J; Rowbottom, MW; Zhang, M; Vickers, T; Sorensen, K; Norton, C; Wen, J; Heise, CE; Saunders, J; Conlon, P; Madan, A; Schwarz, D; Goodfellow, VS Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189584 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189584&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11532402 104073105 CHEMBL379189 ZINC36351521 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50350806 CN(C)[C@H]1CCN(C1)c1ccc(cn1)-n1ncc2cc(-c3ccc(cc3)C(F)(F)F)n(C)c2c1=O InChI=1S/C25H25F3N6O/c1-31(2)20-10-11-33(15-20)22-9-8-19(14-29-22)34-24(35)23-17(13-30-34)12-21(32(23)3)16-4-6-18(7-5-16)25(26,27)28/h4-9,12-14,20H,10-11,15H2,1-3H3/t20-/m0/s1 NZDZGLHHMZPWFD-FQEVSTJZSA-N 50189585 (S)-6-(6-(3-(dimethylamino)pyrrolidin-1-yl)pyridin-3-yl)-1-methyl-2-(4-(trifluoromethyl)phenyl)-1H-pyrrolo[2,3-d]pyridazin-7(6H)-one::CHEMBL379829 Melanin-concentrating hormone receptor 1 Rattus 14 ChEMBL 10.1021/jm051263c 10.7270/Q2Z037SN 16789729 Dyck, B; Markison, S; Zhao, L; Tamiya, J; Grey, J; Rowbottom, MW; Zhang, M; Vickers, T; Sorensen, K; Norton, C; Wen, J; Heise, CE; Saunders, J; Conlon, P; Madan, A; Schwarz, D; Goodfellow, VS Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189585 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189585&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11641550 104073106 CHEMBL379829 ZINC35985443 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50350807 CN[C@@H]1CCN(C1)c1ccc(cn1)-n1ncc2cc(sc2c1=O)-c1ccc(cc1)C(F)(F)F InChI=1S/C23H20F3N5OS/c1-27-17-8-9-30(13-17)20-7-6-18(12-28-20)31-22(32)21-15(11-29-31)10-19(33-21)14-2-4-16(5-3-14)23(24,25)26/h2-7,10-12,17,27H,8-9,13H2,1H3/t17-/m1/s1 VKAMBSPXFFZIQB-QGZVFWFLSA-N 50189576 (R)-6-(6-(3-(methylamino)pyrrolidin-1-yl)pyridin-3-yl)-2-(4-(trifluoromethyl)phenyl)thieno[2,3-d]pyridazin-7(6H)-one::CHEMBL377241 Melanin-concentrating hormone receptor 1 Rattus 3.3 ChEMBL 10.1021/jm051263c 10.7270/Q2Z037SN 16789729 Dyck, B; Markison, S; Zhao, L; Tamiya, J; Grey, J; Rowbottom, MW; Zhang, M; Vickers, T; Sorensen, K; Norton, C; Wen, J; Heise, CE; Saunders, J; Conlon, P; Madan, A; Schwarz, D; Goodfellow, VS Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189576&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11532924 104073097 CHEMBL377241 ZINC34802297 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50350808 CN[C@H]1CCN(C1)c1ccc(cn1)-n1ncc2cc(sc2c1=O)-c1ccc(cc1)C(F)(F)F InChI=1S/C23H20F3N5OS/c1-27-17-8-9-30(13-17)20-7-6-18(12-28-20)31-22(32)21-15(11-29-31)10-19(33-21)14-2-4-16(5-3-14)23(24,25)26/h2-7,10-12,17,27H,8-9,13H2,1H3/t17-/m0/s1 VKAMBSPXFFZIQB-KRWDZBQOSA-N 50189586 (S)-6-(6-(3-(methylamino)pyrrolidin-1-yl)pyridin-3-yl)-2-(4-(trifluoromethyl)phenyl)thieno[2,3-d]pyridazin-7(6H)-one::CHEMBL426507 Melanin-concentrating hormone receptor 1 Rattus 3.1 ChEMBL 10.1021/jm051263c 10.7270/Q2Z037SN 16789729 Dyck, B; Markison, S; Zhao, L; Tamiya, J; Grey, J; Rowbottom, MW; Zhang, M; Vickers, T; Sorensen, K; Norton, C; Wen, J; Heise, CE; Saunders, J; Conlon, P; Madan, A; Schwarz, D; Goodfellow, VS Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189586 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189586&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11511147 104073107 CHEMBL426507 ZINC36351527 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50350809 CN(C)[C@H]1CCN(C1)c1ccc(cn1)-n1ncc2cc(ccc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C25H24ClN5O/c1-29(2)22-11-12-30(16-22)24-10-8-21(15-27-24)31-25(32)23-9-5-18(13-19(23)14-28-31)17-3-6-20(26)7-4-17/h3-10,13-15,22H,11-12,16H2,1-2H3/t22-/m0/s1 LQVKFCWAMKNRJH-QFIPXVFZSA-N 50189587 (S)-6-(4-chlorophenyl)-2-(6-(3-(dimethylamino)pyrrolidin-1-yl)pyridin-3-yl)phthalazin-1(2H)-one::CHEMBL209110 Melanin-concentrating hormone receptor 1 Rattus 1.1 ChEMBL 10.1021/jm051263c 10.7270/Q2Z037SN 16789729 Dyck, B; Markison, S; Zhao, L; Tamiya, J; Grey, J; Rowbottom, MW; Zhang, M; Vickers, T; Sorensen, K; Norton, C; Wen, J; Heise, CE; Saunders, J; Conlon, P; Madan, A; Schwarz, D; Goodfellow, VS Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189587 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189587&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11640865 104073108 CHEMBL209110 ZINC35984682 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50350810 CN[C@@H]1CCN(C1)c1ccc(cn1)-n1ncc2cc(ccc2c1=O)-c1ccc(cc1)C(F)(F)F InChI=1S/C25H22F3N5O/c1-29-20-10-11-32(15-20)23-9-7-21(14-30-23)33-24(34)22-8-4-17(12-18(22)13-31-33)16-2-5-19(6-3-16)25(26,27)28/h2-9,12-14,20,29H,10-11,15H2,1H3/t20-/m1/s1 IGXAHOUGRSJGEA-HXUWFJFHSA-N 50189588 (R)-2-(6-(3-(methylamino)pyrrolidin-1-yl)pyridin-3-yl)-6-(4-(trifluoromethyl)phenyl)phthalazin-1(2H)-one::CHEMBL378309 Melanin-concentrating hormone receptor 1 Rattus 10 ChEMBL 10.1021/jm051263c 10.7270/Q2Z037SN 16789729 Dyck, B; Markison, S; Zhao, L; Tamiya, J; Grey, J; Rowbottom, MW; Zhang, M; Vickers, T; Sorensen, K; Norton, C; Wen, J; Heise, CE; Saunders, J; Conlon, P; Madan, A; Schwarz, D; Goodfellow, VS Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189588 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189588&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11719647 104073109 CHEMBL378309 ZINC34643267 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50350811 CN[C@H]1CCN(C1)c1ccc(cn1)-n1ncc2cc(ccc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C24H22ClN5O/c1-26-20-10-11-29(15-20)23-9-7-21(14-27-23)30-24(31)22-8-4-17(12-18(22)13-28-30)16-2-5-19(25)6-3-16/h2-9,12-14,20,26H,10-11,15H2,1H3/t20-/m0/s1 DAVBMFYLYDYHHC-FQEVSTJZSA-N 50189581 (S)-6-(4-chlorophenyl)-2-(6-(3-(methylamino)pyrrolidin-1-yl)pyridin-3-yl)phthalazin-1(2H)-one::CHEMBL210191 Melanin-concentrating hormone receptor 1 Rattus 1.2 ChEMBL 10.1021/jm051263c 10.7270/Q2Z037SN 16789729 Dyck, B; Markison, S; Zhao, L; Tamiya, J; Grey, J; Rowbottom, MW; Zhang, M; Vickers, T; Sorensen, K; Norton, C; Wen, J; Heise, CE; Saunders, J; Conlon, P; Madan, A; Schwarz, D; Goodfellow, VS Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189581 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189581&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11582824 104073102 CHEMBL210191 ZINC35861370 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50350813 CN[C@H]1CCN(C1)c1ccc(cn1)-n1ncc2cc(ccc2c1=O)-c1ccc(cc1)C(F)(F)F InChI=1S/C25H22F3N5O/c1-29-20-10-11-32(15-20)23-9-7-21(14-30-23)33-24(34)22-8-4-17(12-18(22)13-31-33)16-2-5-19(6-3-16)25(26,27)28/h2-9,12-14,20,29H,10-11,15H2,1H3/t20-/m0/s1 IGXAHOUGRSJGEA-FQEVSTJZSA-N 50189590 (S)-2-(6-(3-(methylamino)pyrrolidin-1-yl)pyridin-3-yl)-6-(4-(trifluoromethyl)phenyl)phthalazin-1(2H)-one::CHEMBL210926 Melanin-concentrating hormone receptor 1 Rattus 8.4 ChEMBL 10.1021/jm051263c 10.7270/Q2Z037SN 16789729 Dyck, B; Markison, S; Zhao, L; Tamiya, J; Grey, J; Rowbottom, MW; Zhang, M; Vickers, T; Sorensen, K; Norton, C; Wen, J; Heise, CE; Saunders, J; Conlon, P; Madan, A; Schwarz, D; Goodfellow, VS Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189590 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189590&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11590806 104073111 CHEMBL210926 ZINC35880237 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50350814 CN[C@@H]1CCN(C1)c1ccc(cn1)-n1ncc2cc(ccc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C24H22ClN5O/c1-26-20-10-11-29(15-20)23-9-7-21(14-27-23)30-24(31)22-8-4-17(12-18(22)13-28-30)16-2-5-19(25)6-3-16/h2-9,12-14,20,26H,10-11,15H2,1H3/t20-/m1/s1 DAVBMFYLYDYHHC-HXUWFJFHSA-N 50189589 (R)-6-(4-chlorophenyl)-2-(6-(3-(methylamino)pyrrolidin-1-yl)pyridin-3-yl)phthalazin-1(2H)-one::CHEMBL211223 Melanin-concentrating hormone receptor 1 Rattus 1.5 ChEMBL 10.1021/jm051263c 10.7270/Q2Z037SN 16789729 Dyck, B; Markison, S; Zhao, L; Tamiya, J; Grey, J; Rowbottom, MW; Zhang, M; Vickers, T; Sorensen, K; Norton, C; Wen, J; Heise, CE; Saunders, J; Conlon, P; Madan, A; Schwarz, D; Goodfellow, VS Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189589 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189589&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11582825 104073110 CHEMBL211223 ZINC35861372 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50350816 CN[C@H]1CCN(C1)c1ccc(cn1)-n1ncc2cc(sc2c1=O)-c1ccc(F)cc1 InChI=1S/C22H20FN5OS/c1-24-17-8-9-27(13-17)20-7-6-18(12-25-20)28-22(29)21-15(11-26-28)10-19(30-21)14-2-4-16(23)5-3-14/h2-7,10-12,17,24H,8-9,13H2,1H3/t17-/m0/s1 GGSZDPGQFROCRJ-KRWDZBQOSA-N 50189593 (S)-2-(4-fluorophenyl)-6-(6-(3-(methylamino)pyrrolidin-1-yl)pyridin-3-yl)thieno[2,3-d]pyridazin-7(6H)-one::CHEMBL379933 Melanin-concentrating hormone receptor 1 Rattus 2 ChEMBL 10.1021/jm051263c 10.7270/Q2Z037SN 16789729 Dyck, B; Markison, S; Zhao, L; Tamiya, J; Grey, J; Rowbottom, MW; Zhang, M; Vickers, T; Sorensen, K; Norton, C; Wen, J; Heise, CE; Saunders, J; Conlon, P; Madan, A; Schwarz, D; Goodfellow, VS Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189593&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11560835 104073114 CHEMBL379933 ZINC35818179 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50350817 CCc1ccc(cc1)-c1cc2cnn(-c3ccc(nc3)N3CC[C@H](C3)NC)c(=O)c2s1 InChI=1S/C24H25N5OS/c1-3-16-4-6-17(7-5-16)21-12-18-13-27-29(24(30)23(18)31-21)20-8-9-22(26-14-20)28-11-10-19(15-28)25-2/h4-9,12-14,19,25H,3,10-11,15H2,1-2H3/t19-/m1/s1 DAWVIISZSJSPPE-LJQANCHMSA-N 50189591 (R)-2-(4-ethylphenyl)-6-(6-(3-(methylamino)pyrrolidin-1-yl)pyridin-3-yl)thieno[2,3-d]pyridazin-7(6H)-one::CHEMBL211340 Melanin-concentrating hormone receptor 1 Rattus 2.6 ChEMBL 10.1021/jm051263c 10.7270/Q2Z037SN 16789729 Dyck, B; Markison, S; Zhao, L; Tamiya, J; Grey, J; Rowbottom, MW; Zhang, M; Vickers, T; Sorensen, K; Norton, C; Wen, J; Heise, CE; Saunders, J; Conlon, P; Madan, A; Schwarz, D; Goodfellow, VS Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189591 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189591&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11626170 104073112 CHEMBL211340 ZINC35951866 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50350818 CN[C@@H]1CCN(C1)c1ccc(cn1)-n1ncc2cc(sc2c1=O)-c1ccc(OC)cc1 InChI=1S/C23H23N5O2S/c1-24-17-9-10-27(14-17)21-8-5-18(13-25-21)28-23(29)22-16(12-26-28)11-20(31-22)15-3-6-19(30-2)7-4-15/h3-8,11-13,17,24H,9-10,14H2,1-2H3/t17-/m1/s1 AMJSRKIPZBGEJM-QGZVFWFLSA-N 50189592 (R)-2-(4-methoxyphenyl)-6-(6-(3-(methylamino)pyrrolidin-1-yl)pyridin-3-yl)thieno[2,3-d]pyridazin-7(6H)-one::CHEMBL208720 Melanin-concentrating hormone receptor 1 Rattus 1.3 ChEMBL 10.1021/jm051263c 10.7270/Q2Z037SN 16789729 Dyck, B; Markison, S; Zhao, L; Tamiya, J; Grey, J; Rowbottom, MW; Zhang, M; Vickers, T; Sorensen, K; Norton, C; Wen, J; Heise, CE; Saunders, J; Conlon, P; Madan, A; Schwarz, D; Goodfellow, VS Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189592 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189592&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11661999 104073113 CHEMBL208720 ZINC36351525 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50350819 CN[C@@H]1CCN(C1)c1ccc(cn1)-n1ncc2cc(sc2c1=O)-c1ccc(F)cc1 InChI=1S/C22H20FN5OS/c1-24-17-8-9-27(13-17)20-7-6-18(12-25-20)28-22(29)21-15(11-26-28)10-19(30-21)14-2-4-16(23)5-3-14/h2-7,10-12,17,24H,8-9,13H2,1H3/t17-/m1/s1 GGSZDPGQFROCRJ-QGZVFWFLSA-N 50189594 (R)-2-(4-fluorophenyl)-6-(6-(3-(methylamino)pyrrolidin-1-yl)pyridin-3-yl)thieno[2,3-d]pyridazin-7(6H)-one::CHEMBL378869 Melanin-concentrating hormone receptor 1 Rattus 2.5 ChEMBL 10.1021/jm051263c 10.7270/Q2Z037SN 16789729 Dyck, B; Markison, S; Zhao, L; Tamiya, J; Grey, J; Rowbottom, MW; Zhang, M; Vickers, T; Sorensen, K; Norton, C; Wen, J; Heise, CE; Saunders, J; Conlon, P; Madan, A; Schwarz, D; Goodfellow, VS Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189594&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11524613 104073115 CHEMBL378869 ZINC36351526 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50354343 CN[C@H]1CCN(C1)c1ccc(cn1)N1Cc2cn(nc2C1=O)-c1ccc(Cl)cc1 InChI=1S/C21H21ClN6O/c1-23-16-8-9-26(13-16)19-7-6-18(10-24-19)27-11-14-12-28(25-20(14)21(27)29)17-4-2-15(22)3-5-17/h2-7,10,12,16,23H,8-9,11,13H2,1H3/t16-/m0/s1 RMCVXAFEIKMTFA-INIZCTEOSA-N 50094880 CHEMBL3589145 Melanin-concentrating hormone receptor 1 Rattus 0.800000 ChEMBL 10.1016/j.bmcl.2015.05.008 10.7270/Q29C7053 26022839 Devasthale, P; Wang, W; Hernandez, AS; Moore, F; Renduchintala, K; Sridhar, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Li, YX; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094880 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094880&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 46188603 318473521 CHEMBL3589145 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50354344 COc1cc(ccc1OCCN1CCCC1)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C25H24ClN3O3S/c1-31-22-14-19(8-9-21(22)32-13-12-28-10-2-3-11-28)29-16-27-20-15-23(33-24(20)25(29)30)17-4-6-18(26)7-5-17/h4-9,14-16H,2-3,10-13H2,1H3 MWULMTACIBZPGN-UHFFFAOYSA-N 50241083 6-(4-chlorophenyl)-3-(3-methoxy-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)thieno[3,2-d]pyrimidin-4(3H)-one::CHEMBL214957::GW-3430 Melanin-concentrating hormone receptor 1 Rattus 0.340000 ChEMBL 10.1016/j.bmcl.2015.05.008 10.7270/Q29C7053 26022839 Devasthale, P; Wang, W; Hernandez, AS; Moore, F; Renduchintala, K; Sridhar, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Li, YX; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241083 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241083&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 9826520 104098586 CHEMBL214957 4033 ZINC03815899 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50354345 COc1cc(ccc1OCC(C)(C)OC(=O)CN)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C25H24ClN3O5S/c1-25(2,34-22(30)12-27)13-33-19-9-8-17(10-20(19)32-3)29-14-28-18-11-21(35-23(18)24(29)31)15-4-6-16(26)7-5-15/h4-11,14H,12-13,27H2,1-3H3 ZYBWJSGMCOVTSU-UHFFFAOYSA-N 50094881 CHEMBL3589155 Melanin-concentrating hormone receptor 1 Rattus 7.2 ChEMBL 10.1016/j.bmcl.2015.05.008 10.7270/Q29C7053 26022839 Devasthale, P; Wang, W; Hernandez, AS; Moore, F; Renduchintala, K; Sridhar, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Li, YX; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094881 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094881&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 122180707 318473522 CHEMBL3589155 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50354351 COc1cc(ccc1OCC(C)(C)OC(=O)CN)N1Cc2cn(nc2C1=O)-c1ccc(Cl)cc1 InChI=1S/C24H25ClN4O5/c1-24(2,34-21(30)11-26)14-33-19-9-8-18(10-20(19)32-3)28-12-15-13-29(27-22(15)23(28)31)17-6-4-16(25)5-7-17/h4-10,13H,11-12,14,26H2,1-3H3 FRJWIYWKCXHSBG-UHFFFAOYSA-N 50094885 CHEMBL3588863 Melanin-concentrating hormone receptor 1 Rattus 3.8 ChEMBL 10.1016/j.bmcl.2015.05.008 10.7270/Q29C7053 26022839 Devasthale, P; Wang, W; Hernandez, AS; Moore, F; Renduchintala, K; Sridhar, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Li, YX; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094885&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 46187172 318473526 CHEMBL3588863 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50385854 Clc1ccc(cc1)-c1ccc(nc1)C#Cc1ccc(OCCN2CCCC2)cc1 InChI=1S/C25H23ClN2O/c26-23-9-6-21(7-10-23)22-8-12-24(27-19-22)11-3-20-4-13-25(14-5-20)29-18-17-28-15-1-2-16-28/h4-10,12-14,19H,1-2,15-18H2 XKNDXALUSFQZAX-UHFFFAOYSA-N 50107746 CHEMBL3600828 Melanin-concentrating hormone receptor 1 Rattus 4.0 ChEMBL 10.1016/j.bmcl.2015.05.077 10.7270/Q25D8TMB 26112443 Müller, SG; Heckel, A; Kley, JT; Lehmann, T; Lustenberger, P; Oost, T; Roth, GJ; Rudolf, K; Arndt, K; Lenter, M; Lotz, RR; Maier, GM; Markert, M; Schindler, M; Stenkamp, D Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107746 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107746&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 9978490 318834953 CHEMBL3600828 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395029 CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCNC(=O)C(c2ccccc2)c2ccccc2)CC1 InChI=1S/C32H39N3O2/c1-24(2)31(36)34-29-16-9-15-28(23-29)25-17-21-35(22-18-25)20-10-19-33-32(37)30(26-11-5-3-6-12-26)27-13-7-4-8-14-27/h3-9,11-16,23-25,30H,10,17-22H2,1-2H3,(H,33,37)(H,34,36) JFSBFNPKAYOILM-UHFFFAOYSA-N 50219023 CHEMBL243138::N-{3-[1-(3-diphenylacetylamino-propyl)-piperidin-4-yl]-phenyl-isobutyramide Melanin-concentrating hormone receptor 1 Rattus 1.9 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219023&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16755871 104092415 CHEMBL243138 ZINC28710171 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395030 CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)[C@@H](C)c2ccccc2)CC1 InChI=1S/C28H39N3O2/c1-20(2)27(32)30-25-12-11-21(3)26(19-25)24-13-17-31(18-14-24)16-8-15-29-28(33)22(4)23-9-6-5-7-10-23/h5-7,9-12,19-20,22,24H,8,13-18H2,1-4H3,(H,29,33)(H,30,32)/t22-/m0/s1 NJJVZQKTUZLDJG-QFIPXVFZSA-N 50219024 2-methyl-N-{4-methyl-3-[1-(3-{[(2R)-2-phenylpropanoyl]-amino}propyl)-4-piperidinyl]phenyl}propanamide::CHEMBL242053 Melanin-concentrating hormone receptor 1 Rattus 68 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219024&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756184 104092416 CHEMBL242053 ZINC28710184 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395031 CC(C)C(=O)Nc1c(F)cc(F)c(C2CCN(CCCNC(=O)C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)c1F InChI=1S/C32H34F5N3O2/c1-19(2)31(41)39-30-26(36)18-25(35)28(29(30)37)22-12-16-40(17-13-22)15-3-14-38-32(42)27(20-4-8-23(33)9-5-20)21-6-10-24(34)11-7-21/h4-11,18-19,22,27H,3,12-17H2,1-2H3,(H,38,42)(H,39,41) KUQDULHGSFIYPI-UHFFFAOYSA-N 50219025 CHEMBL243578::N-{3-[1-(3-{[bis(4-fluorophenyl)acetyl]amino}propyl)-4-piperidinyl]-2,4,6-trifluorophenyl}-2-methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 2.9 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219025&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756074 104092417 CHEMBL243578 ZINC28710179 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395032 CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCNC(=O)C(c2ccc(F)cc2)c2ccc(F)cc2)CC1 InChI=1S/C32H37F2N3O2/c1-22(2)31(38)36-29-6-3-5-26(21-29)23-15-19-37(20-16-23)18-4-17-35-32(39)30(24-7-11-27(33)12-8-24)25-9-13-28(34)14-10-25/h3,5-14,21-23,30H,4,15-20H2,1-2H3,(H,35,39)(H,36,38) MQQZLHMZAFVDKC-UHFFFAOYSA-N 50219026 CHEMBL243338::N-{3-[1-(3-{[bis(4-fluorophenyl)acetyl]amino}propyl)-4-piperidinyl]phenyl}-2-methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 13 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219026&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10369833 104092418 CHEMBL243338 ZINC28710137 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395033 CC(C)C(=O)Nc1cc(ccc1C)C1CCN(CCCNC(=O)C(c2ccccc2)c2ccccc2)CC1 InChI=1S/C33H41N3O2/c1-24(2)32(37)35-30-23-29(16-15-25(30)3)26-17-21-36(22-18-26)20-10-19-34-33(38)31(27-11-6-4-7-12-27)28-13-8-5-9-14-28/h4-9,11-16,23-24,26,31H,10,17-22H2,1-3H3,(H,34,38)(H,35,37) GMRMXYCDJXDFFA-UHFFFAOYSA-N 50219027 CHEMBL388234::N-{3-[1-(3-diphenylacetylamino-propyl)-piperidin-4-yl]-2-methyl-phenyl}-isobutyramide Melanin-concentrating hormone receptor 1 Rattus 500 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219027&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44427407 104092419 CHEMBL388234 ZINC28710180 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395034 CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)[C@H](C)c2ccccc2)CC1 InChI=1S/C28H39N3O2/c1-20(2)27(32)30-25-12-11-21(3)26(19-25)24-13-17-31(18-14-24)16-8-15-29-28(33)22(4)23-9-6-5-7-10-23/h5-7,9-12,19-20,22,24H,8,13-18H2,1-4H3,(H,29,33)(H,30,32)/t22-/m1/s1 NJJVZQKTUZLDJG-JOCHJYFZSA-N 50219028 2-methyl-N-{4-methyl-3-[1-(3-{[(2S)-2-phenylpropanoyl]-amino}propyl)-4-piperidinyl]phenyl}propanamide::CHEMBL242054 Melanin-concentrating hormone receptor 1 Rattus 37 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219028&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10456385 104092420 CHEMBL242054 ZINC28710185 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395035 CC(C)C(=O)Nc1cccc(c1)C1CCN(CCNC(=O)C(c2ccccc2)c2ccccc2)CC1 InChI=1S/C31H37N3O2/c1-23(2)30(35)33-28-15-9-14-27(22-28)24-16-19-34(20-17-24)21-18-32-31(36)29(25-10-5-3-6-11-25)26-12-7-4-8-13-26/h3-15,22-24,29H,16-21H2,1-2H3,(H,32,36)(H,33,35) VSKUPRJZZDVXEM-UHFFFAOYSA-N 50219029 CHEMBL390679::N-{3-[1-(2-diphenylacetylamino-ethyl)-piperidin-4-yl]-phenyl-isobutyramide Melanin-concentrating hormone receptor 1 Rattus 57 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219029&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16755870 104092421 CHEMBL390679 ZINC28710164 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395036 CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCCNC(=O)C(c2ccccc2)c2ccccc2)CC1 InChI=1S/C33H41N3O2/c1-25(2)32(37)35-30-17-11-16-29(24-30)26-18-22-36(23-19-26)21-10-9-20-34-33(38)31(27-12-5-3-6-13-27)28-14-7-4-8-15-28/h3-8,11-17,24-26,31H,9-10,18-23H2,1-2H3,(H,34,38)(H,35,37) IOQFNNLRGSGBGO-UHFFFAOYSA-N 50219030 CHEMBL243139::N-{3-[1-(5-diphenylacetylamino-pentyl)-piperidin-4-yl]-phenyl-isobutyramide Melanin-concentrating hormone receptor 1 Rattus 620 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219030&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16755872 104092422 CHEMBL243139 ZINC28710172 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395037 CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCNC(=O)C(C)(c2ccccc2)c2ccccc2)CC1 InChI=1S/C33H41N3O2/c1-25(2)31(37)35-30-17-10-12-27(24-30)26-18-22-36(23-19-26)21-11-20-34-32(38)33(3,28-13-6-4-7-14-28)29-15-8-5-9-16-29/h4-10,12-17,24-26H,11,18-23H2,1-3H3,(H,34,38)(H,35,37) ZOASIUKCAYWMLK-UHFFFAOYSA-N 50219032 CHEMBL242902::N-(3-{4-[3-(isobutyrylamino)phenyl]-1-piperidinyl}propyl)-2,2-diphenylpropanamide Melanin-concentrating hormone receptor 1 Rattus 7.5 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219032&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16755969 104092424 CHEMBL242902 ZINC28710126 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395038 CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)C2(CCCC2)c2ccc(F)cc2)CC1 InChI=1S/C31H42FN3O2/c1-22(2)29(36)34-27-12-7-23(3)28(21-27)24-13-19-35(20-14-24)18-6-17-33-30(37)31(15-4-5-16-31)25-8-10-26(32)11-9-25/h7-12,21-22,24H,4-6,13-20H2,1-3H3,(H,33,37)(H,34,36) BMVZQYRVHRLKTR-UHFFFAOYSA-N 50219031 1-(4-fluorophenyl)-N-(3-{4-[5-(isobutylamino)-2-methylphenyl]-1-piperidinyl}propyl)cyclohexanecarboxamide::CHEMBL244370 Melanin-concentrating hormone receptor 1 Rattus 3.8 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219031&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756187 104092423 CHEMBL244370 ZINC28710189 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395039 COCC1=C([C@@H](N(C(=O)NCCCN2CCC(CC2)c2cccc(NC(C)=O)c2)C(=O)N1)c1ccc(F)c(F)c1)C(=O)OC InChI=1S/C31H37F2N5O6/c1-19(39)35-23-7-4-6-21(16-23)20-10-14-37(15-11-20)13-5-12-34-30(41)38-28(22-8-9-24(32)25(33)17-22)27(29(40)44-3)26(18-43-2)36-31(38)42/h4,6-9,16-17,20,28H,5,10-15,18H2,1-3H3,(H,34,41)(H,35,39)(H,36,42)/t28-/m0/s1 FWMHZWMPUWAUPL-NDEPHWFRSA-N 50152456 (S)-3-{3-[4-(3-Acetylamino-phenyl)-piperidin-1-yl]-propylcarbamoyl}-4-(3,4-difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester::(S)-methyl 1-((3-(4-(3-acetamidophenyl)piperidin-1-yl)propyl)carbamoyl)-6-(3,4-difluorophenyl)-4-(methoxymethyl)-2-oxo-1,2,3,6-tetrahydropyrimidine-5-carboxylate::CHEMBL185271 Melanin-concentrating hormone receptor 1 Rattus 0.25 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152456&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11520239 104040521 CHEMBL185271 ZINC03966030 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395040 CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCCNC(=O)C(c2ccccc2)c2ccccc2)CC1 InChI=1S/C33H41N3O2/c1-25(2)32(37)35-30-17-11-16-29(24-30)26-18-22-36(23-19-26)21-10-9-20-34-33(38)31(27-12-5-3-6-13-27)28-14-7-4-8-15-28/h3-8,11-17,24-26,31H,9-10,18-23H2,1-2H3,(H,34,38)(H,35,37) IOQFNNLRGSGBGO-UHFFFAOYSA-N 50219030 CHEMBL243139::N-{3-[1-(5-diphenylacetylamino-pentyl)-piperidin-4-yl]-phenyl-isobutyramide Melanin-concentrating hormone receptor 1 Rattus 50 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219030&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16755872 104092422 CHEMBL243139 ZINC28710172 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395041 CC(C)C(=O)Nc1cccc(c1)C1CCN(CCNC(=O)C(c2ccccc2)c2ccccc2)CC1 InChI=1S/C31H37N3O2/c1-23(2)30(35)33-28-15-9-14-27(22-28)24-16-19-34(20-17-24)21-18-32-31(36)29(25-10-5-3-6-11-25)26-12-7-4-8-13-26/h3-15,22-24,29H,16-21H2,1-2H3,(H,32,36)(H,33,35) VSKUPRJZZDVXEM-UHFFFAOYSA-N 50219029 CHEMBL390679::N-{3-[1-(2-diphenylacetylamino-ethyl)-piperidin-4-yl]-phenyl-isobutyramide Melanin-concentrating hormone receptor 1 Rattus 1.9 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219029&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16755870 104092421 CHEMBL390679 ZINC28710164 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395042 CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)C2(CCCC2)c2ccc(F)cc2)CC1 InChI=1S/C31H42FN3O2/c1-22(2)29(36)34-27-12-7-23(3)28(21-27)24-13-19-35(20-14-24)18-6-17-33-30(37)31(15-4-5-16-31)25-8-10-26(32)11-9-25/h7-12,21-22,24H,4-6,13-20H2,1-3H3,(H,33,37)(H,34,36) BMVZQYRVHRLKTR-UHFFFAOYSA-N 50219031 1-(4-fluorophenyl)-N-(3-{4-[5-(isobutylamino)-2-methylphenyl]-1-piperidinyl}propyl)cyclohexanecarboxamide::CHEMBL244370 Melanin-concentrating hormone receptor 1 Rattus 44 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219031&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756187 104092423 CHEMBL244370 ZINC28710189 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395043 CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCCCNC(=O)C(c2ccccc2)c2ccccc2)CC1 InChI=1S/C34H43N3O2/c1-26(2)33(38)36-31-18-12-17-30(25-31)27-19-23-37(24-20-27)22-11-5-10-21-35-34(39)32(28-13-6-3-7-14-28)29-15-8-4-9-16-29/h3-4,6-9,12-18,25-27,32H,5,10-11,19-24H2,1-2H3,(H,35,39)(H,36,38) PZSAAJDAUJLGEO-UHFFFAOYSA-N 50219033 CHEMBL243354::N-{3-[1-(5-diphenylacetylamino-pentyl)-piperidin-4-yl]-phenyl-isobutyramide Melanin-concentrating hormone receptor 1 Rattus 47 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219033&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16755967 104092425 CHEMBL243354 ZINC28710174 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395044 CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCCCCNC(=O)C(c2ccccc2)c2ccccc2)CC1 InChI=1S/C35H45N3O2/c1-27(2)34(39)37-32-19-13-18-31(26-32)28-20-24-38(25-21-28)23-12-4-3-11-22-36-35(40)33(29-14-7-5-8-15-29)30-16-9-6-10-17-30/h5-10,13-19,26-28,33H,3-4,11-12,20-25H2,1-2H3,(H,36,40)(H,37,39) OCZOHPQRIJVMGG-UHFFFAOYSA-N 50219034 CHEMBL243129::N-{3-[1-(6-diphenylacetylamino-hexyl)-piperidin-4-yl]-phenyl-isobutyramide Melanin-concentrating hormone receptor 1 Rattus 29 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219034 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219034&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16755968 104092426 CHEMBL243129 ZINC28710134 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395045 CC(C)C(=O)Nc1cc(C2CCN(CCCNC(=O)C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)c(F)cc1F InChI=1S/C32H35F4N3O2/c1-20(2)31(40)38-29-18-26(27(35)19-28(29)36)21-12-16-39(17-13-21)15-3-14-37-32(41)30(22-4-8-24(33)9-5-22)23-6-10-25(34)11-7-23/h4-11,18-21,30H,3,12-17H2,1-2H3,(H,37,41)(H,38,40) PHZFASCDZWDOQJ-UHFFFAOYSA-N 50219035 CHEMBL243355::N-{5-[1-(3-{[bis(4-fluorophenyl)acetyl]amino}propyl)-4-piperidinyl]-2,4-difluorophenyl}-2-methylpropanamide::SNAP-102739 Melanin-concentrating hormone receptor 1 Rattus 1.8 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219035 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219035&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10437982 104092427 CHEMBL243355 ZINC28710177 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395046 CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)C(O)(c2ccccc2)c2ccccc2)CC1 InChI=1S/C33H41N3O3/c1-24(2)31(37)35-29-16-15-25(3)30(23-29)26-17-21-36(22-18-26)20-10-19-34-32(38)33(39,27-11-6-4-7-12-27)28-13-8-5-9-14-28/h4-9,11-16,23-24,26,39H,10,17-22H2,1-3H3,(H,34,38)(H,35,37) INMZLZRTJQLJQQ-UHFFFAOYSA-N 50219036 CHEMBL388440::N-{3-[1-(3-{[hydroxy(diphenyl)acetyl]amino}propyl)-4-piperidinyl]-4-methylphenyl}-2-methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 0.6 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219036 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219036&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10324628 104092428 CHEMBL388440 ZINC28710181 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395047 CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)[C@H](C)c2ccc(F)cc2)CC1 InChI=1S/C28H38FN3O2/c1-19(2)27(33)31-25-11-6-20(3)26(18-25)23-12-16-32(17-13-23)15-5-14-30-28(34)21(4)22-7-9-24(29)10-8-22/h6-11,18-19,21,23H,5,12-17H2,1-4H3,(H,30,34)(H,31,33)/t21-/m1/s1 AFEOXYGIEXXWKX-OAQYLSRUSA-N 50219039 (2R)-2-(4-fluorophenyl)-N-(3-{4-[5-(isobutyrylamino)-2-methylphenyl]-1-piperidinyl}propyl)propanamide::CHEMBL244369 Melanin-concentrating hormone receptor 1 Rattus 65 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219039&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756186 104092431 CHEMBL244369 ZINC28710187 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395048 CCCCCC(C(=O)NCCCN1CCC(CC1)c1cccc(NC(=O)C(C)C)c1)(c1ccccc1)c1ccccc1 InChI=1S/C37H49N3O2/c1-4-5-12-23-37(32-16-8-6-9-17-32,33-18-10-7-11-19-33)36(42)38-24-14-25-40-26-21-30(22-27-40)31-15-13-20-34(28-31)39-35(41)29(2)3/h6-11,13,15-20,28-30H,4-5,12,14,21-27H2,1-3H3,(H,38,42)(H,39,41) ZSVOQOFSUFNFFR-UHFFFAOYSA-N 50219038 CHEMBL243507::N-(3-{4-[3-(isobutylrylamino)phenyl]-1-piperidinyl}propyl)-2,2-diphenylheptanamide Melanin-concentrating hormone receptor 1 Rattus 8.5 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219038 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219038&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16755971 104092430 CHEMBL243507 ZINC28710120 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395049 CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)C2(CCCCC2)c2ccc(F)cc2)CC1 InChI=1S/C32H44FN3O2/c1-23(2)30(37)35-28-13-8-24(3)29(22-28)25-14-20-36(21-15-25)19-7-18-34-31(38)32(16-5-4-6-17-32)26-9-11-27(33)12-10-26/h8-13,22-23,25H,4-7,14-21H2,1-3H3,(H,34,38)(H,35,37) MEPMSZIBYJDWKM-UHFFFAOYSA-N 50219037 1-(4-fluorophenyl)-N-(3-{4-[5-(isobutyrylamino)-2-methylphenyl]-1-piperidinyl}propyl)cyclopentanecarboxamide::CHEMBL396234 Melanin-concentrating hormone receptor 1 Rattus 1.9 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219037 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219037&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756284 104092429 CHEMBL396234 ZINC28710188 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395050 CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)C2(CCCCC2)c2ccc(F)cc2)CC1 InChI=1S/C32H44FN3O2/c1-23(2)30(37)35-28-13-8-24(3)29(22-28)25-14-20-36(21-15-25)19-7-18-34-31(38)32(16-5-4-6-17-32)26-9-11-27(33)12-10-26/h8-13,22-23,25H,4-7,14-21H2,1-3H3,(H,34,38)(H,35,37) MEPMSZIBYJDWKM-UHFFFAOYSA-N 50219037 1-(4-fluorophenyl)-N-(3-{4-[5-(isobutyrylamino)-2-methylphenyl]-1-piperidinyl}propyl)cyclopentanecarboxamide::CHEMBL396234 Melanin-concentrating hormone receptor 1 Rattus 190 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219037 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219037&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756284 104092429 CHEMBL396234 ZINC28710188 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395051 CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)[C@H](C)c2ccc(F)cc2)CC1 InChI=1S/C28H38FN3O2/c1-19(2)27(33)31-25-11-6-20(3)26(18-25)23-12-16-32(17-13-23)15-5-14-30-28(34)21(4)22-7-9-24(29)10-8-22/h6-11,18-19,21,23H,5,12-17H2,1-4H3,(H,30,34)(H,31,33)/t21-/m1/s1 AFEOXYGIEXXWKX-OAQYLSRUSA-N 50219039 (2R)-2-(4-fluorophenyl)-N-(3-{4-[5-(isobutyrylamino)-2-methylphenyl]-1-piperidinyl}propyl)propanamide::CHEMBL244369 Melanin-concentrating hormone receptor 1 Rattus 28 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219039&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756186 104092431 CHEMBL244369 ZINC28710187 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395052 CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)C(O)(c2ccccc2)c2ccccc2)CC1 InChI=1S/C33H41N3O3/c1-24(2)31(37)35-29-16-15-25(3)30(23-29)26-17-21-36(22-18-26)20-10-19-34-32(38)33(39,27-11-6-4-7-12-27)28-13-8-5-9-14-28/h4-9,11-16,23-24,26,39H,10,17-22H2,1-3H3,(H,34,38)(H,35,37) INMZLZRTJQLJQQ-UHFFFAOYSA-N 50219036 CHEMBL388440::N-{3-[1-(3-{[hydroxy(diphenyl)acetyl]amino}propyl)-4-piperidinyl]-4-methylphenyl}-2-methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 27 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219036 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219036&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10324628 104092428 CHEMBL388440 ZINC28710181 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395053 CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)C(c2ccc(F)cc2)c2ccc(F)cc2)CC1 InChI=1S/C33H39F2N3O2/c1-22(2)32(39)37-29-14-5-23(3)30(21-29)24-15-19-38(20-16-24)18-4-17-36-33(40)31(25-6-10-27(34)11-7-25)26-8-12-28(35)13-9-26/h5-14,21-22,24,31H,4,15-20H2,1-3H3,(H,36,40)(H,37,39) OJVUOPKFXPMGGA-UHFFFAOYSA-N 50219040 CHEMBL429464::N-{3-[1-(3-{[bis(4-fluorophenyl)acetyl]amino}propyl)-4-piperidinyl]-4-methylphenyl}-2-methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 27 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219040 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219040&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756072 104092432 CHEMBL429464 ZINC28710119 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395054 CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)[C@@H](C)c2ccccc2)CC1 InChI=1S/C28H39N3O2/c1-20(2)27(32)30-25-12-11-21(3)26(19-25)24-13-17-31(18-14-24)16-8-15-29-28(33)22(4)23-9-6-5-7-10-23/h5-7,9-12,19-20,22,24H,8,13-18H2,1-4H3,(H,29,33)(H,30,32)/t22-/m0/s1 NJJVZQKTUZLDJG-QFIPXVFZSA-N 50219024 2-methyl-N-{4-methyl-3-[1-(3-{[(2R)-2-phenylpropanoyl]-amino}propyl)-4-piperidinyl]phenyl}propanamide::CHEMBL242053 Melanin-concentrating hormone receptor 1 Rattus 34 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219024&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756184 104092416 CHEMBL242053 ZINC28710184 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395055 CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)C(c2ccc(F)cc2)c2ccc(F)cc2)CC1 InChI=1S/C33H39F2N3O2/c1-22(2)32(39)37-29-14-5-23(3)30(21-29)24-15-19-38(20-16-24)18-4-17-36-33(40)31(25-6-10-27(34)11-7-25)26-8-12-28(35)13-9-26/h5-14,21-22,24,31H,4,15-20H2,1-3H3,(H,36,40)(H,37,39) OJVUOPKFXPMGGA-UHFFFAOYSA-N 50219040 CHEMBL429464::N-{3-[1-(3-{[bis(4-fluorophenyl)acetyl]amino}propyl)-4-piperidinyl]-4-methylphenyl}-2-methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 0.62 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219040 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219040&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756072 104092432 CHEMBL429464 ZINC28710119 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395056 CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCCCCNC(=O)C(c2ccccc2)c2ccccc2)CC1 InChI=1S/C35H45N3O2/c1-27(2)34(39)37-32-19-13-18-31(26-32)28-20-24-38(25-21-28)23-12-4-3-11-22-36-35(40)33(29-14-7-5-8-15-29)30-16-9-6-10-17-30/h5-10,13-19,26-28,33H,3-4,11-12,20-25H2,1-2H3,(H,36,40)(H,37,39) OCZOHPQRIJVMGG-UHFFFAOYSA-N 50219034 CHEMBL243129::N-{3-[1-(6-diphenylacetylamino-hexyl)-piperidin-4-yl]-phenyl-isobutyramide Melanin-concentrating hormone receptor 1 Rattus 600 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219034 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219034&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16755968 104092426 CHEMBL243129 ZINC28710134 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395057 CCC(C(=O)NCCCN1CCC(CC1)c1cccc(NC(=O)C(C)C)c1)(c1ccccc1)c1ccccc1 InChI=1S/C34H43N3O2/c1-4-34(29-14-7-5-8-15-29,30-16-9-6-10-17-30)33(39)35-21-12-22-37-23-19-27(20-24-37)28-13-11-18-31(25-28)36-32(38)26(2)3/h5-11,13-18,25-27H,4,12,19-24H2,1-3H3,(H,35,39)(H,36,38) GDXCCQORISFUQU-UHFFFAOYSA-N 50219041 CHEMBL242901::N-{3-[4-(3-isobutyrylamino-phenyl)-piperidin-1-yl]-propyl}-2,2-diphenyl-butyramide Melanin-concentrating hormone receptor 1 Rattus 14 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219041 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219041&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16755970 104092433 CHEMBL242901 ZINC28710121 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395058 CC(C)C(=O)Nc1cc(C2CCN(CCCNC(=O)C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)c(F)cc1F InChI=1S/C32H35F4N3O2/c1-20(2)31(40)38-29-18-26(27(35)19-28(29)36)21-12-16-39(17-13-21)15-3-14-37-32(41)30(22-4-8-24(33)9-5-22)23-6-10-25(34)11-7-23/h4-11,18-21,30H,3,12-17H2,1-2H3,(H,37,41)(H,38,40) PHZFASCDZWDOQJ-UHFFFAOYSA-N 50219035 CHEMBL243355::N-{5-[1-(3-{[bis(4-fluorophenyl)acetyl]amino}propyl)-4-piperidinyl]-2,4-difluorophenyl}-2-methylpropanamide::SNAP-102739 Melanin-concentrating hormone receptor 1 Rattus 34 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219035 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219035&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10437982 104092427 CHEMBL243355 ZINC28710177 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395059 CC(C)C(=O)Nc1cc(ccc1C)C1CCN(CCCNC(=O)C(c2ccccc2)c2ccccc2)CC1 InChI=1S/C33H41N3O2/c1-24(2)32(37)35-30-23-29(16-15-25(30)3)26-17-21-36(22-18-26)20-10-19-34-33(38)31(27-11-6-4-7-12-27)28-13-8-5-9-14-28/h4-9,11-16,23-24,26,31H,10,17-22H2,1-3H3,(H,34,38)(H,35,37) GMRMXYCDJXDFFA-UHFFFAOYSA-N 50219027 CHEMBL388234::N-{3-[1-(3-diphenylacetylamino-propyl)-piperidin-4-yl]-2-methyl-phenyl}-isobutyramide Melanin-concentrating hormone receptor 1 Rattus >1000 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219027&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44427407 104092419 CHEMBL388234 ZINC28710180 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395060 CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)[C@H](C)c2ccccc2)CC1 InChI=1S/C28H39N3O2/c1-20(2)27(32)30-25-12-11-21(3)26(19-25)24-13-17-31(18-14-24)16-8-15-29-28(33)22(4)23-9-6-5-7-10-23/h5-7,9-12,19-20,22,24H,8,13-18H2,1-4H3,(H,29,33)(H,30,32)/t22-/m1/s1 NJJVZQKTUZLDJG-JOCHJYFZSA-N 50219028 2-methyl-N-{4-methyl-3-[1-(3-{[(2S)-2-phenylpropanoyl]-amino}propyl)-4-piperidinyl]phenyl}propanamide::CHEMBL242054 Melanin-concentrating hormone receptor 1 Rattus 130 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219028&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10456385 104092420 CHEMBL242054 ZINC28710185 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395061 CCC(C(=O)NCCCN1CCC(CC1)c1cccc(NC(=O)C(C)C)c1)(c1ccccc1)c1ccccc1 InChI=1S/C34H43N3O2/c1-4-34(29-14-7-5-8-15-29,30-16-9-6-10-17-30)33(39)35-21-12-22-37-23-19-27(20-24-37)28-13-11-18-31(25-28)36-32(38)26(2)3/h5-11,13-18,25-27H,4,12,19-24H2,1-3H3,(H,35,39)(H,36,38) GDXCCQORISFUQU-UHFFFAOYSA-N 50219041 CHEMBL242901::N-{3-[4-(3-isobutyrylamino-phenyl)-piperidin-1-yl]-propyl}-2,2-diphenyl-butyramide Melanin-concentrating hormone receptor 1 Rattus 190 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219041 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219041&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16755970 104092433 CHEMBL242901 ZINC28710121 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395062 CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCNC(=O)C(c2ccccc2)c2ccccc2)CC1 InChI=1S/C32H39N3O2/c1-24(2)31(36)34-29-16-9-15-28(23-29)25-17-21-35(22-18-25)20-10-19-33-32(37)30(26-11-5-3-6-12-26)27-13-7-4-8-14-27/h3-9,11-16,23-25,30H,10,17-22H2,1-2H3,(H,33,37)(H,34,36) JFSBFNPKAYOILM-UHFFFAOYSA-N 50219023 CHEMBL243138::N-{3-[1-(3-diphenylacetylamino-propyl)-piperidin-4-yl]-phenyl-isobutyramide Melanin-concentrating hormone receptor 1 Rattus 25 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219023&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16755871 104092415 CHEMBL243138 ZINC28710171 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395063 CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCNC(=O)C(c2ccc(F)cc2)c2ccc(F)cc2)CC1 InChI=1S/C32H37F2N3O2/c1-22(2)31(38)36-29-6-3-5-26(21-29)23-15-19-37(20-16-23)18-4-17-35-32(39)30(24-7-11-27(33)12-8-24)25-9-13-28(34)14-10-25/h3,5-14,21-23,30H,4,15-20H2,1-2H3,(H,35,39)(H,36,38) MQQZLHMZAFVDKC-UHFFFAOYSA-N 50219026 CHEMBL243338::N-{3-[1-(3-{[bis(4-fluorophenyl)acetyl]amino}propyl)-4-piperidinyl]phenyl}-2-methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 1.4 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219026&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10369833 104092418 CHEMBL243338 ZINC28710137 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395064 CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCNC(=O)C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)CC1 InChI=1S/C32H37Cl2N3O2/c1-22(2)31(38)36-29-6-3-5-26(21-29)23-15-19-37(20-16-23)18-4-17-35-32(39)30(24-7-11-27(33)12-8-24)25-9-13-28(34)14-10-25/h3,5-14,21-23,30H,4,15-20H2,1-2H3,(H,35,39)(H,36,38) FEDJKFPVWLWPSG-UHFFFAOYSA-N 50219044 CHEMBL243128::N-{3-[1-(3-{[bis(4-chlorophenyl)acetyl]amino}propyl)-4-piperidinyl]phenyl}-2-methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 2.4 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219044 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219044&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10325618 104092436 CHEMBL243128 ZINC28710130 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395065 CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCNC(=O)C(C)(c2ccccc2)c2ccccc2)CC1 InChI=1S/C33H41N3O2/c1-25(2)31(37)35-30-17-10-12-27(24-30)26-18-22-36(23-19-26)21-11-20-34-32(38)33(3,28-13-6-4-7-14-28)29-15-8-5-9-16-29/h4-10,12-17,24-26H,11,18-23H2,1-3H3,(H,34,38)(H,35,37) ZOASIUKCAYWMLK-UHFFFAOYSA-N 50219032 CHEMBL242902::N-(3-{4-[3-(isobutyrylamino)phenyl]-1-piperidinyl}propyl)-2,2-diphenylpropanamide Melanin-concentrating hormone receptor 1 Rattus 140 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219032&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16755969 104092424 CHEMBL242902 ZINC28710126 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395066 CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)C(c2ccccc2)c2ccccc2)CC1 InChI=1S/C33H41N3O2/c1-24(2)32(37)35-29-16-15-25(3)30(23-29)26-17-21-36(22-18-26)20-10-19-34-33(38)31(27-11-6-4-7-12-27)28-13-8-5-9-14-28/h4-9,11-16,23-24,26,31H,10,17-22H2,1-3H3,(H,34,38)(H,35,37) UBAAMKRAOLDWBF-UHFFFAOYSA-N 50219042 CHEMBL242689::N-[3-(1-{3-[(diphenylacetyl)amino]propyl}-4-piperidinyl)-4-methylphenyl]-2-methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 3 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219042&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756073 104092434 CHEMBL242689 ZINC28710114 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395067 CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)C(c2ccccc2)c2ccccc2)CC1 InChI=1S/C33H41N3O2/c1-24(2)32(37)35-29-16-15-25(3)30(23-29)26-17-21-36(22-18-26)20-10-19-34-33(38)31(27-11-6-4-7-12-27)28-13-8-5-9-14-28/h4-9,11-16,23-24,26,31H,10,17-22H2,1-3H3,(H,34,38)(H,35,37) UBAAMKRAOLDWBF-UHFFFAOYSA-N 50219042 CHEMBL242689::N-[3-(1-{3-[(diphenylacetyl)amino]propyl}-4-piperidinyl)-4-methylphenyl]-2-methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 27 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219042&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756073 104092434 CHEMBL242689 ZINC28710114 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395068 CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)[C@@H](C)c2ccc(F)cc2)CC1 InChI=1S/C28H38FN3O2/c1-19(2)27(33)31-25-11-6-20(3)26(18-25)23-12-16-32(17-13-23)15-5-14-30-28(34)21(4)22-7-9-24(29)10-8-22/h6-11,18-19,21,23H,5,12-17H2,1-4H3,(H,30,34)(H,31,33)/t21-/m0/s1 AFEOXYGIEXXWKX-NRFANRHFSA-N 50219043 (2S)-2-(4-fluorophenyl)-N-(3-{4-[5-(isobutyrylamino)-2-methylphenyl]-1-piperidinyl}propyl)propanamide::CHEMBL394793 Melanin-concentrating hormone receptor 1 Rattus 26 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219043&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756185 104092435 CHEMBL394793 ZINC28710186 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395069 CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)[C@@H](C)c2ccc(F)cc2)CC1 InChI=1S/C28H38FN3O2/c1-19(2)27(33)31-25-11-6-20(3)26(18-25)23-12-16-32(17-13-23)15-5-14-30-28(34)21(4)22-7-9-24(29)10-8-22/h6-11,18-19,21,23H,5,12-17H2,1-4H3,(H,30,34)(H,31,33)/t21-/m0/s1 AFEOXYGIEXXWKX-NRFANRHFSA-N 50219043 (2S)-2-(4-fluorophenyl)-N-(3-{4-[5-(isobutyrylamino)-2-methylphenyl]-1-piperidinyl}propyl)propanamide::CHEMBL394793 Melanin-concentrating hormone receptor 1 Rattus 10 ChEMBL 10.1021/jm060381c 10.7270/Q2930SWM 17668921 Jiang, Y; Chen, CA; Lu, K; Daniewska, I; De Leon, J; Kong, R; Forray, C; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219043&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756185 104092435 CHEMBL394793 ZINC28710186 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395070 CC(C)C(=O)Nc1cc(ccc1C)C1CCN(Cc2ccc(Oc3ccc(F)c(F)c3)cc2)CC1 InChI=1S/C29H32F2N2O2/c1-19(2)29(34)32-28-16-23(7-4-20(28)3)22-12-14-33(15-13-22)18-21-5-8-24(9-6-21)35-25-10-11-26(30)27(31)17-25/h4-11,16-17,19,22H,12-15,18H2,1-3H3,(H,32,34) ZYUVYNFTIYISBW-UHFFFAOYSA-N 50219045 CHEMBL242003::N-(5-{1-[4-(3,4-difluorophenoxy)benzyl]-4-piperidinyl}-4-methylphenyl)-2-methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 27 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219045&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756753 104092437 CHEMBL242003 ZINC28710590 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395071 CC(=O)Nc1cccc(c1)C1CCN(CCCC(=O)c2ccccc2)CC1 InChI=1S/C23H28N2O2/c1-18(26)24-22-10-5-9-21(17-22)19-12-15-25(16-13-19)14-6-11-23(27)20-7-3-2-4-8-20/h2-5,7-10,17,19H,6,11-16H2,1H3,(H,24,26) WECKOLSWDLQBNC-UHFFFAOYSA-N 50219046 CHEMBL395788::N-{3-[1-(4-oxo-4-phenylbutyl)-4-piperidinyl]phenyl}-acetamide Melanin-concentrating hormone receptor 1 Rattus 350 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219046&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756401 104092438 CHEMBL395788 ZINC28710557 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395072 Clc1ccc(cc1)C(=O)CCCN1CCC(CC1)c1cccc(NC(=O)Cc2ccccc2)c1 InChI=1S/C29H31ClN2O2/c30-26-13-11-24(12-14-26)28(33)10-5-17-32-18-15-23(16-19-32)25-8-4-9-27(21-25)31-29(34)20-22-6-2-1-3-7-22/h1-4,6-9,11-14,21,23H,5,10,15-20H2,(H,31,34) UIHOENHXMONZDL-UHFFFAOYSA-N 50219048 CHEMBL244372::N-(3-{1-[4-(4-chlorophenyl)-4-oxobutyl]-4-piperidinyl}phenyl)-2-phenylacetamide Melanin-concentrating hormone receptor 1 Rattus 84 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219048&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756520 104092440 CHEMBL244372 ZINC28710574 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395073 OC1(CCN(CCCC(=O)c2ccc(Cl)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23Cl2NO2/c22-18-7-3-16(4-8-18)20(25)2-1-13-24-14-11-21(26,12-15-24)17-5-9-19(23)10-6-17/h3-10,26H,1-2,11-15H2 QETRGFJTEVVJTC-UHFFFAOYSA-N 50219049 1-(4-Chloro-phenyl)-4-[4-(4-chloro-phenyl)-4-hydroxy-piperidin-1-yl]-butan-1-one::1-(4-chlorophenyl)-4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)butan-1-one::CHEMBL363548 Melanin-concentrating hormone receptor 1 Rattus 350 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219049 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219049&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 173712 104092441 CHEMBL363548 ZINC02516029 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395074 CC(C)C(=O)Nc1cc(ccc1C)C1CCN(Cc2ccc(Oc3ccc(F)c(F)c3)cc2)CC1 InChI=1S/C29H32F2N2O2/c1-19(2)29(34)32-28-16-23(7-4-20(28)3)22-12-14-33(15-13-22)18-21-5-8-24(9-6-21)35-25-10-11-26(30)27(31)17-25/h4-11,16-17,19,22H,12-15,18H2,1-3H3,(H,32,34) ZYUVYNFTIYISBW-UHFFFAOYSA-N 50219045 CHEMBL242003::N-(5-{1-[4-(3,4-difluorophenoxy)benzyl]-4-piperidinyl}-4-methylphenyl)-2-methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 360 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219045&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756753 104092437 CHEMBL242003 ZINC28710590 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395076 CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2ccc(Oc3ccc(Cl)c(Cl)c3)cc2)CC1 InChI=1S/C28H30Cl2N2O2/c1-19(2)28(33)31-23-5-3-4-22(16-23)21-12-14-32(15-13-21)18-20-6-8-24(9-7-20)34-25-10-11-26(29)27(30)17-25/h3-11,16-17,19,21H,12-15,18H2,1-2H3,(H,31,33) TVUCFWYHYFWZFI-UHFFFAOYSA-N 50219050 CHEMBL389129::N-(3-{1-[4-(3,4-dichlorophenoxy)benzyl]-4-piperidinyl}phenyl)-2-methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 8.2 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219050 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219050&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756752 104092442 CHEMBL389129 ZINC28710588 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395077 COc1ccc(Oc2ccc(CN3CCC(CC3)c3cccc(NC(=O)C(C)C)c3)cc2)cc1 InChI=1S/C29H34N2O3/c1-21(2)29(32)30-25-6-4-5-24(19-25)23-15-17-31(18-16-23)20-22-7-9-27(10-8-22)34-28-13-11-26(33-3)12-14-28/h4-14,19,21,23H,15-18,20H2,1-3H3,(H,30,32) RBVKMXSYCQGAEL-UHFFFAOYSA-N 50219051 CHEMBL245229::N-(3-{1-[4-(4-methoxyphenoxy)benzyl]-4-piperidinyl}phenyl)-2-methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 35 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219051&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756751 104092443 CHEMBL245229 ZINC28710586 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395078 CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2cccc(Oc3cccc(c3)C(F)(F)F)c2)CC1 InChI=1S/C29H31F3N2O2/c1-20(2)28(35)33-25-9-4-7-23(17-25)22-12-14-34(15-13-22)19-21-6-3-10-26(16-21)36-27-11-5-8-24(18-27)29(30,31)32/h3-11,16-18,20,22H,12-15,19H2,1-2H3,(H,33,35) RQFGRKWTNDBOJO-UHFFFAOYSA-N 50219052 2-methyl-N-[3-(1-{3-[3-(trifluoromethyl)phenoxy]benzyl}-4-piperidinyl)phenyl]-propanamide::CHEMBL244790 Melanin-concentrating hormone receptor 1 Rattus 5400 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219052 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219052&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756638 104092444 CHEMBL244790 ZINC28710580 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395079 CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(Cc2ccc(Oc3ccc(F)c(F)c3)cc2)CC1 InChI=1S/C29H32F2N2O2/c1-19(2)29(34)32-23-7-4-20(3)26(16-23)22-12-14-33(15-13-22)18-21-5-8-24(9-6-21)35-25-10-11-27(30)28(31)17-25/h4-11,16-17,19,22H,12-15,18H2,1-3H3,(H,32,34) VMLZFUVIKCGATC-UHFFFAOYSA-N 50219053 CHEMBL242004::N-(3-{1-4-(3,4-difluorophenoxy)benzyl]-4-piperidinyl}-4-methylphenyl)-2-methylpropanamide::SNAP-94847 Melanin-concentrating hormone receptor 1 Rattus 230 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219053&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756754 104092445 CHEMBL242004 ZINC03961758 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395080 CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2ccc(Oc3ccccc3)cc2)CC1 InChI=1S/C28H32N2O2/c1-21(2)28(31)29-25-8-6-7-24(19-25)23-15-17-30(18-16-23)20-22-11-13-27(14-12-22)32-26-9-4-3-5-10-26/h3-14,19,21,23H,15-18,20H2,1-2H3,(H,29,31) BNQLJQAWDJNCDL-UHFFFAOYSA-N 50219054 2-methyl-N-{3-[1-(4-phenoxybenzyl)-4-piperidinyl]phenyl}-propanamide::CHEMBL389128 Melanin-concentrating hormone receptor 1 Rattus 320 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219054 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219054&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756641 104092446 CHEMBL389128 ZINC28710583 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395082 CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2cccc(Oc3ccc(Cl)c(Cl)c3)c2)CC1 InChI=1S/C28H30Cl2N2O2/c1-19(2)28(33)31-23-7-4-6-22(16-23)21-11-13-32(14-12-21)18-20-5-3-8-24(15-20)34-25-9-10-26(29)27(30)17-25/h3-10,15-17,19,21H,11-14,18H2,1-2H3,(H,31,33) PRZKEUYSBKIHQC-UHFFFAOYSA-N 50219055 CHEMBL244791::N-(3-{1-[3-(3,4-dichlorophenoxy)benzyl]-4-piperidinyl}phenyl)-2methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 18 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219055 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219055&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756639 104092447 CHEMBL244791 ZINC28710581 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395085 CC(=O)Nc1cccc(c1)C1CCN(CCCC(=O)c2ccc(Oc3ccccc3)cc2)CC1 InChI=1S/C29H32N2O3/c1-22(32)30-26-8-5-7-25(21-26)23-16-19-31(20-17-23)18-6-11-29(33)24-12-14-28(15-13-24)34-27-9-3-2-4-10-27/h2-5,7-10,12-15,21,23H,6,11,16-20H2,1H3,(H,30,32) HKIBDKKNDIBQNU-UHFFFAOYSA-N 50219060 CHEMBL244003::N-(3-{1-[4-oxo-4-(4-phenoxyphenyl)butyl)-4-piperidinyl}phenyl)-acetamide Melanin-concentrating hormone receptor 1 Rattus >10000 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219060 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219060&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756404 104092452 CHEMBL244003 ZINC28710561 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395086 Clc1ccc(cc1)C(=O)CCCN1CCC(CC1)c1cccc(NC(=O)C2CCCCC2)c1 InChI=1S/C28H35ClN2O2/c29-25-13-11-22(12-14-25)27(32)10-5-17-31-18-15-21(16-19-31)24-8-4-9-26(20-24)30-28(33)23-6-2-1-3-7-23/h4,8-9,11-14,20-21,23H,1-3,5-7,10,15-19H2,(H,30,33) LMCSTGAXXHEOCA-UHFFFAOYSA-N 50219056 CHEMBL244163::N-(3-{1-[4-(4-chlorophenyl)-4-oxobutyl]-4-piperidinyl}phenyl)-cyclohexanecarboxamide Melanin-concentrating hormone receptor 1 Rattus 200 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219056 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219056&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756519 104092448 CHEMBL244163 ZINC28710573 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395087 CC(=O)Nc1cccc(c1)C1CCN(CCCC(=O)c2ccccc2)CC1 InChI=1S/C23H28N2O2/c1-18(26)24-22-10-5-9-21(17-22)19-12-15-25(16-13-19)14-6-11-23(27)20-7-3-2-4-8-20/h2-5,7-10,17,19H,6,11-16H2,1H3,(H,24,26) WECKOLSWDLQBNC-UHFFFAOYSA-N 50219046 CHEMBL395788::N-{3-[1-(4-oxo-4-phenylbutyl)-4-piperidinyl]phenyl}-acetamide Melanin-concentrating hormone receptor 1 Rattus 2700 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219046&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756401 104092438 CHEMBL395788 ZINC28710557 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395088 CC(=O)Nc1cccc(c1)C1CCN(CCCC(=O)c2ccc(C)c(C)c2)CC1 InChI=1S/C25H32N2O2/c1-18-9-10-23(16-19(18)2)25(29)8-5-13-27-14-11-21(12-15-27)22-6-4-7-24(17-22)26-20(3)28/h4,6-7,9-10,16-17,21H,5,8,11-15H2,1-3H3,(H,26,28) ZGGXNCTZASWEAU-UHFFFAOYSA-N 50219058 CHEMBL244004::N-(3-{1-[4-(3,4-dimethylphenyl)-4-oxobutyl]-4-piperidinyl}phenyl)-acetamide Melanin-concentrating hormone receptor 1 Rattus 1300 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219058 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219058&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756405 104092450 CHEMBL244004 ZINC28710562 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395089 CC(=O)Nc1cccc(c1)C1CCN(CCCC(=O)c2ccc(C)cc2)CC1 InChI=1S/C24H30N2O2/c1-18-8-10-21(11-9-18)24(28)7-4-14-26-15-12-20(13-16-26)22-5-3-6-23(17-22)25-19(2)27/h3,5-6,8-11,17,20H,4,7,12-16H2,1-2H3,(H,25,27) MRSTZRHYYBFJBO-UHFFFAOYSA-N 50219057 CHEMBL395789::N-(3-{1-[4-(4-methylphenyl)-4-oxobutyl]-4-piperidinyl}phenyl}-acetamide Melanin-concentrating hormone receptor 1 Rattus 2400 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219057 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219057&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756403 104092449 CHEMBL395789 ZINC28710560 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395090 CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(Cc2ccc(Oc3ccc(F)c(F)c3)cc2)CC1 InChI=1S/C29H32F2N2O2/c1-19(2)29(34)32-23-7-4-20(3)26(16-23)22-12-14-33(15-13-22)18-21-5-8-24(9-6-21)35-25-10-11-27(30)28(31)17-25/h4-11,16-17,19,22H,12-15,18H2,1-3H3,(H,32,34) VMLZFUVIKCGATC-UHFFFAOYSA-N 50219053 CHEMBL242004::N-(3-{1-4-(3,4-difluorophenoxy)benzyl]-4-piperidinyl}-4-methylphenyl)-2-methylpropanamide::SNAP-94847 Melanin-concentrating hormone receptor 1 Rattus 2.2 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219053&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756754 104092445 CHEMBL242004 ZINC03961758 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395091 COCC1=C([C@@H](N(C(=O)NCCCN2CCC(CC2)c2cccc(NC(C)=O)c2)C(=O)N1)c1ccc(F)c(F)c1)C(=O)OC InChI=1S/C31H37F2N5O6/c1-19(39)35-23-7-4-6-21(16-23)20-10-14-37(15-11-20)13-5-12-34-30(41)38-28(22-8-9-24(32)25(33)17-22)27(29(40)44-3)26(18-43-2)36-31(38)42/h4,6-9,16-17,20,28H,5,10-15,18H2,1-3H3,(H,34,41)(H,35,39)(H,36,42)/t28-/m0/s1 FWMHZWMPUWAUPL-NDEPHWFRSA-N 50152456 (S)-3-{3-[4-(3-Acetylamino-phenyl)-piperidin-1-yl]-propylcarbamoyl}-4-(3,4-difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester::(S)-methyl 1-((3-(4-(3-acetamidophenyl)piperidin-1-yl)propyl)carbamoyl)-6-(3,4-difluorophenyl)-4-(methoxymethyl)-2-oxo-1,2,3,6-tetrahydropyrimidine-5-carboxylate::CHEMBL185271 Melanin-concentrating hormone receptor 1 Rattus 0.25 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152456&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11520239 104040521 CHEMBL185271 ZINC03966030 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395093 CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2cccc(Oc3cccc(c3)C(F)(F)F)c2)CC1 InChI=1S/C29H31F3N2O2/c1-20(2)28(35)33-25-9-4-7-23(17-25)22-12-14-34(15-13-22)19-21-6-3-10-26(16-21)36-27-11-5-8-24(18-27)29(30,31)32/h3-11,16-18,20,22H,12-15,19H2,1-2H3,(H,33,35) RQFGRKWTNDBOJO-UHFFFAOYSA-N 50219052 2-methyl-N-[3-(1-{3-[3-(trifluoromethyl)phenoxy]benzyl}-4-piperidinyl)phenyl]-propanamide::CHEMBL244790 Melanin-concentrating hormone receptor 1 Rattus 65 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219052 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219052&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756638 104092444 CHEMBL244790 ZINC28710580 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395094 CC(=O)Nc1cccc(c1)C1CCN(CCCC(=O)c2ccc(Oc3ccccc3)cc2)CC1 InChI=1S/C29H32N2O3/c1-22(32)30-26-8-5-7-25(21-26)23-16-19-31(20-17-23)18-6-11-29(33)24-12-14-28(15-13-24)34-27-9-3-2-4-10-27/h2-5,7-10,12-15,21,23H,6,11,16-20H2,1H3,(H,30,32) HKIBDKKNDIBQNU-UHFFFAOYSA-N 50219060 CHEMBL244003::N-(3-{1-[4-oxo-4-(4-phenoxyphenyl)butyl)-4-piperidinyl}phenyl)-acetamide Melanin-concentrating hormone receptor 1 Rattus 490 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219060 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219060&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756404 104092452 CHEMBL244003 ZINC28710561 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395095 CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCC(=O)c2ccc(Cl)cc2)CC1 InChI=1S/C25H31ClN2O2/c1-18(2)25(30)27-23-6-3-5-21(17-23)19-12-15-28(16-13-19)14-4-7-24(29)20-8-10-22(26)11-9-20/h3,5-6,8-11,17-19H,4,7,12-16H2,1-2H3,(H,27,30) XZHJITMMAUAOIV-UHFFFAOYSA-N 50219062 CHEMBL394569::N-(3-{1-[4-(4-chlorophenyl)-4-oxobutyl]-4-piperidinyl}phenyl)-2-methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 5 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219062 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219062&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10137322 104092454 CHEMBL394569 ZINC28710563 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395096 CC(=O)Nc1cccc(c1)C1CCN(CCCC(=O)c2ccc(Cl)cc2)CC1 InChI=1S/C23H27ClN2O2/c1-17(27)25-22-5-2-4-20(16-22)18-11-14-26(15-12-18)13-3-6-23(28)19-7-9-21(24)10-8-19/h2,4-5,7-10,16,18H,3,6,11-15H2,1H3,(H,25,27) CVIMVOKGOJOOSP-UHFFFAOYSA-N 50219061 CHEMBL243794::N-(3-{1-[4-(4-chlorophenyl)-4-oxobutyl)-4-piperidinyl]phenyl}-acetamide Melanin-concentrating hormone receptor 1 Rattus 70 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219061 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219061&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756402 104092453 CHEMBL243794 ZINC28710559 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395099 CC(=O)Nc1cccc(c1)C1CCN(CCCC(=O)c2ccc(Cl)cc2)CC1 InChI=1S/C23H27ClN2O2/c1-17(27)25-22-5-2-4-20(16-22)18-11-14-26(15-12-18)13-3-6-23(28)19-7-9-21(24)10-8-19/h2,4-5,7-10,16,18H,3,6,11-15H2,1H3,(H,25,27) CVIMVOKGOJOOSP-UHFFFAOYSA-N 50219061 CHEMBL243794::N-(3-{1-[4-(4-chlorophenyl)-4-oxobutyl)-4-piperidinyl]phenyl}-acetamide Melanin-concentrating hormone receptor 1 Rattus 570 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219061 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219061&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756402 104092453 CHEMBL243794 ZINC28710559 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395100 CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2ccc(Oc3ccc(F)c(F)c3)cc2)CC1 InChI=1S/C28H30F2N2O2/c1-19(2)28(33)31-23-5-3-4-22(16-23)21-12-14-32(15-13-21)18-20-6-8-24(9-7-20)34-25-10-11-26(29)27(30)17-25/h3-11,16-17,19,21H,12-15,18H2,1-2H3,(H,31,33) MJDBJIACJNGVIM-UHFFFAOYSA-N 50219047 CHEMBL245231::N-(3-(1-(4-(3,4-difluorophenoxy)benzyl)piperidin-4-yl)phenyl)isobutyramide::N-(3-{1-[4-(3,4-difluorophenoxy)benzyl]-4-piperidinyl}phenyl)-2-methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 110 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219047&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10183297 104092439 CHEMBL245231 ZINC28710589 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395102 CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCC(=O)c2ccc(Cl)cc2)CC1 InChI=1S/C25H31ClN2O2/c1-18(2)25(30)27-23-6-3-5-21(17-23)19-12-15-28(16-13-19)14-4-7-24(29)20-8-10-22(26)11-9-20/h3,5-6,8-11,17-19H,4,7,12-16H2,1-2H3,(H,27,30) XZHJITMMAUAOIV-UHFFFAOYSA-N 50219062 CHEMBL394569::N-(3-{1-[4-(4-chlorophenyl)-4-oxobutyl]-4-piperidinyl}phenyl)-2-methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 72 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219062 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219062&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10137322 104092454 CHEMBL394569 ZINC28710563 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395104 CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2cccc(Oc3ccccc3)c2)CC1 InChI=1S/C28H32N2O2/c1-21(2)28(31)29-25-10-7-9-24(19-25)23-14-16-30(17-15-23)20-22-8-6-13-27(18-22)32-26-11-4-3-5-12-26/h3-13,18-19,21,23H,14-17,20H2,1-2H3,(H,29,31) SYTDFMKLDHALDH-UHFFFAOYSA-N 50219063 2-methyl-N-{3-[1-(3-phenoxybenzyl)-4-piperidinyl]phenyl}-propanamide::CHEMBL244373 Melanin-concentrating hormone receptor 1 Rattus 28 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219063 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219063&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756521 104092455 CHEMBL244373 ZINC28710575 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395105 CC(=O)Nc1cccc(c1)C1CCN(CCCC(=O)c2ccc(C)cc2)CC1 InChI=1S/C24H30N2O2/c1-18-8-10-21(11-9-18)24(28)7-4-14-26-15-12-20(13-16-26)22-5-3-6-23(17-22)25-19(2)27/h3,5-6,8-11,17,20H,4,7,12-16H2,1-2H3,(H,25,27) MRSTZRHYYBFJBO-UHFFFAOYSA-N 50219057 CHEMBL395789::N-(3-{1-[4-(4-methylphenyl)-4-oxobutyl]-4-piperidinyl}phenyl}-acetamide Melanin-concentrating hormone receptor 1 Rattus 360 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219057 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219057&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756403 104092449 CHEMBL395789 ZINC28710560 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395107 CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2cccc(Oc3ccc(C)cc3)c2)CC1 InChI=1S/C29H34N2O2/c1-21(2)29(32)30-26-8-5-7-25(19-26)24-14-16-31(17-15-24)20-23-6-4-9-28(18-23)33-27-12-10-22(3)11-13-27/h4-13,18-19,21,24H,14-17,20H2,1-3H3,(H,30,32) XVSVZEAYULOQSI-UHFFFAOYSA-N 50219065 2-methyl-N-(3-{1-[3-(4-methylphenoxy)benzyl]-4-piperidinyl}phenyl)-propanamide::CHEMBL244374 Melanin-concentrating hormone receptor 1 Rattus 31 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219065&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756522 104092457 CHEMBL244374 ZINC28710576 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395112 CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2cccc(Oc3cc(Cl)cc(Cl)c3)c2)CC1 InChI=1S/C28H30Cl2N2O2/c1-19(2)28(33)31-25-7-4-6-22(14-25)21-9-11-32(12-10-21)18-20-5-3-8-26(13-20)34-27-16-23(29)15-24(30)17-27/h3-8,13-17,19,21H,9-12,18H2,1-2H3,(H,31,33) WDQSMVXIRWFSBZ-UHFFFAOYSA-N 50219068 CHEMBL245008::N-(3-{1-[3-(3,5-dichlorophenoxy)benzyl]-4-piperidinyl}phenyl)-2methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 1400 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219068 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219068&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756640 104092460 CHEMBL245008 ZINC28710582 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395113 CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2ccc(Oc3ccc(Cl)cc3)cc2)CC1 InChI=1S/C28H31ClN2O2/c1-20(2)28(32)30-25-5-3-4-23(18-25)22-14-16-31(17-15-22)19-21-6-10-26(11-7-21)33-27-12-8-24(29)9-13-27/h3-13,18,20,22H,14-17,19H2,1-2H3,(H,30,32) INIGBMVFQMXBFW-UHFFFAOYSA-N 50219064 CHEMBL245010::N-(3-{1-[4-(4-chlorophenoxy)benzyl]-4-piperidinyl}phenyl)-2-methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 5.3 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219064&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756642 104092456 CHEMBL245010 ZINC28710585 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395114 CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2cccc(Oc3ccc(Cl)cc3)c2)CC1 InChI=1S/C28H31ClN2O2/c1-20(2)28(32)30-25-7-4-6-23(18-25)22-13-15-31(16-14-22)19-21-5-3-8-27(17-21)33-26-11-9-24(29)10-12-26/h3-12,17-18,20,22H,13-16,19H2,1-2H3,(H,30,32) WBQHYELYVXDTRY-UHFFFAOYSA-N 50219066 CHEMBL244578::N-(3-{1-[3-(4-chlorophenoxy)benzyl]-4-piperidinyl}phenyl)-2methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 23 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219066&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756637 104092458 CHEMBL244578 ZINC28710579 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395116 COc1ccc(Oc2cccc(CN3CCC(CC3)c3cccc(NC(=O)C(C)C)c3)c2)cc1 InChI=1S/C29H34N2O3/c1-21(2)29(32)30-25-8-5-7-24(19-25)23-14-16-31(17-15-23)20-22-6-4-9-28(18-22)34-27-12-10-26(33-3)11-13-27/h4-13,18-19,21,23H,14-17,20H2,1-3H3,(H,30,32) JGHHCQJAWMYFGE-UHFFFAOYSA-N 50219059 CHEMBL390212::N-(3-{1-[3-(4-methoxyphenoxy)benzyl]-4-piperidinyl}phenyl)-2methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 43 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219059 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219059&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756524 104092451 CHEMBL390212 ZINC28710578 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395119 CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2ccc(Oc3ccccc3)cc2)CC1 InChI=1S/C28H32N2O2/c1-21(2)28(31)29-25-8-6-7-24(19-25)23-15-17-30(18-16-23)20-22-11-13-27(14-12-22)32-26-9-4-3-5-10-26/h3-14,19,21,23H,15-18,20H2,1-2H3,(H,29,31) BNQLJQAWDJNCDL-UHFFFAOYSA-N 50219054 2-methyl-N-{3-[1-(4-phenoxybenzyl)-4-piperidinyl]phenyl}-propanamide::CHEMBL389128 Melanin-concentrating hormone receptor 1 Rattus 10 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219054 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219054&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756641 104092446 CHEMBL389128 ZINC28710583 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395120 COc1ccc(Oc2ccc(CN3CCC(CC3)c3cccc(NC(=O)C(C)C)c3)cc2)cc1 InChI=1S/C29H34N2O3/c1-21(2)29(32)30-25-6-4-5-24(19-25)23-15-17-31(18-16-23)20-22-7-9-27(10-8-22)34-28-13-11-26(33-3)12-14-28/h4-14,19,21,23H,15-18,20H2,1-3H3,(H,30,32) RBVKMXSYCQGAEL-UHFFFAOYSA-N 50219051 CHEMBL245229::N-(3-{1-[4-(4-methoxyphenoxy)benzyl]-4-piperidinyl}phenyl)-2-methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 720 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219051&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756751 104092443 CHEMBL245229 ZINC28710586 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395121 CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2cccc(Oc3ccc(Cl)c(Cl)c3)c2)CC1 InChI=1S/C28H30Cl2N2O2/c1-19(2)28(33)31-23-7-4-6-22(16-23)21-11-13-32(14-12-21)18-20-5-3-8-24(15-20)34-25-9-10-26(29)27(30)17-25/h3-10,15-17,19,21H,11-14,18H2,1-2H3,(H,31,33) PRZKEUYSBKIHQC-UHFFFAOYSA-N 50219055 CHEMBL244791::N-(3-{1-[3-(3,4-dichlorophenoxy)benzyl]-4-piperidinyl}phenyl)-2methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 2600 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219055 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219055&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756639 104092447 CHEMBL244791 ZINC28710581 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395122 CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2cccc(Oc3ccc(cc3)C(C)(C)C)c2)CC1 InChI=1S/C32H40N2O2/c1-23(2)31(35)33-28-10-7-9-26(21-28)25-16-18-34(19-17-25)22-24-8-6-11-30(20-24)36-29-14-12-27(13-15-29)32(3,4)5/h6-15,20-21,23,25H,16-19,22H2,1-5H3,(H,33,35) LBFKAYUDAAUXBV-UHFFFAOYSA-N 50219067 CHEMBL244576::N-(3-{1-[3-(4-tert-butylphenoxy)benzyl]-4-piperidinyl}phenyl)-2methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 540 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219067&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756523 104092459 CHEMBL244576 ZINC28710577 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395125 CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2ccc(Oc3ccc(F)c(F)c3)cc2)CC1 InChI=1S/C28H30F2N2O2/c1-19(2)28(33)31-23-5-3-4-22(16-23)21-12-14-32(15-13-21)18-20-6-8-24(9-7-20)34-25-10-11-26(29)27(30)17-25/h3-11,16-17,19,21H,12-15,18H2,1-2H3,(H,31,33) MJDBJIACJNGVIM-UHFFFAOYSA-N 50219047 CHEMBL245231::N-(3-(1-(4-(3,4-difluorophenoxy)benzyl)piperidin-4-yl)phenyl)isobutyramide::N-(3-{1-[4-(3,4-difluorophenoxy)benzyl]-4-piperidinyl}phenyl)-2-methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 1.8 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219047&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10183297 104092439 CHEMBL245231 ZINC28710589 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395127 CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2cccc(Oc3cc(Cl)cc(Cl)c3)c2)CC1 InChI=1S/C28H30Cl2N2O2/c1-19(2)28(33)31-25-7-4-6-22(14-25)21-9-11-32(12-10-21)18-20-5-3-8-26(13-20)34-27-16-23(29)15-24(30)17-27/h3-8,13-17,19,21H,9-12,18H2,1-2H3,(H,31,33) WDQSMVXIRWFSBZ-UHFFFAOYSA-N 50219068 CHEMBL245008::N-(3-{1-[3-(3,5-dichlorophenoxy)benzyl]-4-piperidinyl}phenyl)-2methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 140 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219068 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219068&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756640 104092460 CHEMBL245008 ZINC28710582 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395128 CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2ccc(Oc3ccc(Cl)c(Cl)c3)cc2)CC1 InChI=1S/C28H30Cl2N2O2/c1-19(2)28(33)31-23-5-3-4-22(16-23)21-12-14-32(15-13-21)18-20-6-8-24(9-7-20)34-25-10-11-26(29)27(30)17-25/h3-11,16-17,19,21H,12-15,18H2,1-2H3,(H,31,33) TVUCFWYHYFWZFI-UHFFFAOYSA-N 50219050 CHEMBL389129::N-(3-{1-[4-(3,4-dichlorophenoxy)benzyl]-4-piperidinyl}phenyl)-2-methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 710 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219050 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219050&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756752 104092442 CHEMBL389129 ZINC28710588 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395129 CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2ccc(Oc3ccc(Cl)cc3)cc2)CC1 InChI=1S/C28H31ClN2O2/c1-20(2)28(32)30-25-5-3-4-23(18-25)22-14-16-31(17-15-22)19-21-6-10-26(11-7-21)33-27-12-8-24(29)9-13-27/h3-13,18,20,22H,14-17,19H2,1-2H3,(H,30,32) INIGBMVFQMXBFW-UHFFFAOYSA-N 50219064 CHEMBL245010::N-(3-{1-[4-(4-chlorophenoxy)benzyl]-4-piperidinyl}phenyl)-2-methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 350 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219064&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756642 104092456 CHEMBL245010 ZINC28710585 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395130 CC(=O)Nc1cccc(c1)C1CCN(CCCC(=O)c2ccc(C)c(C)c2)CC1 InChI=1S/C25H32N2O2/c1-18-9-10-23(16-19(18)2)25(29)8-5-13-27-14-11-21(12-15-27)22-6-4-7-24(17-22)26-20(3)28/h4,6-7,9-10,16-17,21H,5,8,11-15H2,1-3H3,(H,26,28) ZGGXNCTZASWEAU-UHFFFAOYSA-N 50219058 CHEMBL244004::N-(3-{1-[4-(3,4-dimethylphenyl)-4-oxobutyl]-4-piperidinyl}phenyl)-acetamide Melanin-concentrating hormone receptor 1 Rattus 100 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219058 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219058&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756405 104092450 CHEMBL244004 ZINC28710562 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50395132 CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2cccc(Oc3ccc(Cl)cc3)c2)CC1 InChI=1S/C28H31ClN2O2/c1-20(2)28(32)30-25-7-4-6-23(18-25)22-13-15-31(16-14-22)19-21-5-3-8-27(17-21)33-26-11-9-24(29)10-12-26/h3-12,17-18,20,22H,13-16,19H2,1-2H3,(H,30,32) WBQHYELYVXDTRY-UHFFFAOYSA-N 50219066 CHEMBL244578::N-(3-{1-[3-(4-chlorophenoxy)benzyl]-4-piperidinyl}phenyl)-2methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 2000 ChEMBL 10.1021/jm060383x 10.7270/Q25D8RJM 17668922 Chen, CA; Jiang, Y; Lu, K; Daniewska, I; Mazza, CG; Negron, L; Forray, C; Parola, T; Li, B; Hegde, LG; Wolinsky, TD; Craig, DA; Kong, R; Wetzel, JM; Andersen, K; Marzabadi, MR Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219066&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16756637 104092458 CHEMBL244578 ZINC28710579 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50385575 COc1ccc(COc2cnn(CC(=O)c3ccc(CN(C)C)cc3C)c(=O)c2)nc1 InChI=1S/C23H26N4O4/c1-16-9-17(13-26(2)3)5-8-21(16)22(28)14-27-23(29)10-20(12-25-27)31-15-18-6-7-19(30-4)11-24-18/h5-12H,13-15H2,1-4H3 ACBKFGPDANWBLT-UHFFFAOYSA-N 142122 US8933079, 149::US8933079, 150::US8933079, 9.1 Melanin-concentrating hormone receptor 1 Rattus 18 ChEMBL 10.1016/j.bmcl.2015.05.065 10.7270/Q2T43VV4 26105194 Oost, T; Heckel, A; Kley, JT; Lehmann, T; Müller, S; Roth, GJ; Rudolf, K; Arndt, K; Budzinski, R; Lenter, M; Lotz, RR; Maier, GM; Markert, M; Thomas, L; Stenkamp, D Boehringer Ingelheim Pharma GmbH & Co. KG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=142122 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=142122&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 71714121 251920124 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411398 COc1cc(ccc1OCC(C)(C)O)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C23H21ClN2O4S/c1-23(2,28)12-30-18-9-8-16(10-19(18)29-3)26-13-25-17-11-20(31-21(17)22(26)27)14-4-6-15(24)7-5-14/h4-11,13,28H,12H2,1-3H3 GRPZZKMUWKOODM-UHFFFAOYSA-N 50094884 CHEMBL3589154 Melanin-concentrating hormone receptor 1 Rattus 7.2 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094884&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 16718619 318473525 CHEMBL3589154 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411475 COc1cc(ccc1OCC(C)(C)O)-n1cnn2cc(cc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C23H22ClN3O4/c1-23(2,29)13-31-20-9-8-18(11-21(20)30-3)26-14-25-27-12-16(10-19(27)22(26)28)15-4-6-17(24)7-5-15/h4-12,14,29H,13H2,1-3H3 GDEZUWDWHVVOHV-UHFFFAOYSA-N 50120629 CHEMBL3618336 Melanin-concentrating hormone receptor 1 Rattus 1.8 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120629 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120629&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45279402 104013680 CHEMBL3618336 ZINC13819607 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411478 OC1CCN(CC1)c1ccc(cn1)-n1cnn2cc(cc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C22H20ClN5O2/c23-17-3-1-15(2-4-17)16-11-20-22(30)27(14-25-28(20)13-16)18-5-6-21(24-12-18)26-9-7-19(29)8-10-26/h1-6,11-14,19,29H,7-10H2 GFGHQEWOLXQMRD-UHFFFAOYSA-N 50120623 CHEMBL3618335 Melanin-concentrating hormone receptor 1 Rattus 18 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120623 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120623&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45279680 104013674 CHEMBL3618335 ZINC13819673 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411488 OC1CN(C1)C1CCN(C1)c1ccc(cn1)-n1cnn2cc(cc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C24H23ClN6O2/c25-18-3-1-16(2-4-18)17-9-22-24(33)30(15-27-31(22)11-17)19-5-6-23(26-10-19)28-8-7-20(12-28)29-13-21(32)14-29/h1-6,9-11,15,20-21,32H,7-8,12-14H2 NAYKAMBMTPIGPM-UHFFFAOYSA-N 50120628 CHEMBL3618334 Melanin-concentrating hormone receptor 1 Rattus 1.4 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120628 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120628&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45279869 104013679 CHEMBL3618334 ZINC13819699 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411490 O[C@@H]1CCN(C1)c1ccc(cn1)-n1cnn2cc(cc2c1=O)-c1ccc(Cl)cn1 InChI=1S/C20H17ClN6O2/c21-14-1-3-17(22-8-14)13-7-18-20(29)26(12-24-27(18)10-13)15-2-4-19(23-9-15)25-6-5-16(28)11-25/h1-4,7-10,12,16,28H,5-6,11H2/t16-/m1/s1 KBAHMTHILGZKOB-MRXNPFEDSA-N 50120627 CHEMBL3618333 Melanin-concentrating hormone receptor 1 Rattus 54 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120627 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120627&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45278576 104013678 CHEMBL3618333 ZINC13819650 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411498 O[C@@H]1CCN(C1)c1ccc(cn1)-n1cnn2cc(cc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C21H18ClN5O2/c22-16-3-1-14(2-4-16)15-9-19-21(29)26(13-24-27(19)11-15)17-5-6-20(23-10-17)25-8-7-18(28)12-25/h1-6,9-11,13,18,28H,7-8,12H2/t18-/m1/s1 RGMCYARQJKEXRX-GOSISDBHSA-N 50120630 CHEMBL3618332 Melanin-concentrating hormone receptor 1 Rattus 5.5 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120630 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120630&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45279773 104013681 CHEMBL3618332 ZINC13819709 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411499 OC1CN(C1)c1ccc(cn1)-n1cnn2cc(cc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C20H16ClN5O2/c21-15-3-1-13(2-4-15)14-7-18-20(28)25(12-23-26(18)9-14)16-5-6-19(22-8-16)24-10-17(27)11-24/h1-9,12,17,27H,10-11H2 WVDWBRFTMSOBSU-UHFFFAOYSA-N 50120626 CHEMBL3618331 Melanin-concentrating hormone receptor 1 Rattus 14 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120626 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120626&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45279772 104013677 CHEMBL3618331 ZINC13819703 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411507 CNC1CCN(C1)c1ccc(cn1)-n1cnn2cc(cc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C22H21ClN6O/c1-24-18-8-9-27(13-18)21-7-6-19(11-25-21)28-14-26-29-12-16(10-20(29)22(28)30)15-2-4-17(23)5-3-15/h2-7,10-12,14,18,24H,8-9,13H2,1H3 ZBPPNVLOMMAFMB-UHFFFAOYSA-N 50120625 CHEMBL3618330 Melanin-concentrating hormone receptor 1 Rattus 0.300000 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120625 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120625&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45279585 104013676 CHEMBL3618330 ZINC13819707 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411508 COc1cc(ccc1OCC(O)C1CC1)-n1cnn2cc(nc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C23H21ClN4O4/c1-31-21-10-17(8-9-20(21)32-12-19(29)15-2-3-15)27-13-25-28-11-18(26-22(28)23(27)30)14-4-6-16(24)7-5-14/h4-11,13,15,19,29H,2-3,12H2,1H3 NGHQAEQUCRYTTM-UHFFFAOYSA-N 50120631 CHEMBL3618329 Melanin-concentrating hormone receptor 1 Rattus 18 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120631 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120631&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45278977 104013682 CHEMBL3618329 ZINC13819697 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411511 COc1cc(ccc1OCC(O)C1CC1)-n1cnn2nc(cc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C23H21ClN4O4/c1-31-22-10-17(8-9-21(22)32-12-20(29)15-2-3-15)27-13-25-28-19(23(27)30)11-18(26-28)14-4-6-16(24)7-5-14/h4-11,13,15,20,29H,2-3,12H2,1H3 DXLNSICNAKMOOX-UHFFFAOYSA-N 50120632 CHEMBL3618328 Melanin-concentrating hormone receptor 1 Rattus 13 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120632 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120632&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 58423512 104013683 CHEMBL3618328 ZINC13819725 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411512 COc1cc(ccc1OCC(O)C1CC1)-n1cnn2cc(cc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C24H22ClN3O4/c1-31-23-11-19(8-9-22(23)32-13-21(29)16-2-3-16)27-14-26-28-12-17(10-20(28)24(27)30)15-4-6-18(25)7-5-15/h4-12,14,16,21,29H,2-3,13H2,1H3 HJNTUQUTZWHBEL-UHFFFAOYSA-N 50120633 CHEMBL3618327 Melanin-concentrating hormone receptor 1 Rattus 2.8 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120633 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120633&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45279489 104013684 CHEMBL3618327 ZINC13819723 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411513 COc1cc(ccc1OCCN1CCCC1)-n1cnn2cc(nc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C24H24ClN5O3/c1-32-22-14-19(8-9-21(22)33-13-12-28-10-2-3-11-28)29-16-26-30-15-20(27-23(30)24(29)31)17-4-6-18(25)7-5-17/h4-9,14-16H,2-3,10-13H2,1H3 ZOKRNWQUAKWYOX-UHFFFAOYSA-N 50120634 CHEMBL3618326 Melanin-concentrating hormone receptor 1 Rattus 2.6 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120634&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45279493 104013685 CHEMBL3618326 ZINC13819613 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411515 COc1cc(ccc1OCCN1CCCC1)-n1cnn2nc(cc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C24H24ClN5O3/c1-32-23-14-19(8-9-22(23)33-13-12-28-10-2-3-11-28)29-16-26-30-21(24(29)31)15-20(27-30)17-4-6-18(25)7-5-17/h4-9,14-16H,2-3,10-13H2,1H3 RROGKYWCMQVOCW-UHFFFAOYSA-N 50120635 CHEMBL3618325 Melanin-concentrating hormone receptor 1 Rattus 0.500000 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120635 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120635&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45278579 104013686 CHEMBL3618325 ZINC13819675 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411540 COc1cc(ccc1N1CC[C@@H](O)C1)-n1cnn2cc(cc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C23H21ClN4O3/c1-31-22-11-18(6-7-20(22)26-9-8-19(29)13-26)27-14-25-28-12-16(10-21(28)23(27)30)15-2-4-17(24)5-3-15/h2-7,10-12,14,19,29H,8-9,13H2,1H3/t19-/m1/s1 CSUYOWVTAHGJSU-LJQANCHMSA-N 50120674 CHEMBL3618337 Melanin-concentrating hormone receptor 1 Rattus 4.7 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120674 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120674&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45279583 319566003 CHEMBL3618337 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411541 COc1cc(ccc1N1C[C@H](O)[C@H](O)C1)-n1cnn2cc(cc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C23H21ClN4O4/c1-32-22-9-17(6-7-18(22)26-11-20(29)21(30)12-26)27-13-25-28-10-15(8-19(28)23(27)31)14-2-4-16(24)5-3-14/h2-10,13,20-21,29-30H,11-12H2,1H3/t20-,21+ JYORAMBSJLKFFO-OYRHEFFESA-N 50120670 CHEMBL3618338 Melanin-concentrating hormone receptor 1 Rattus 2.3 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120670 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120670&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45279868 319565999 CHEMBL3618338 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411542 COc1cc(ccc1OCC1(O)CC(F)(F)C1)-n1cnn2cc(cc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C24H20ClF2N3O4/c1-33-21-9-18(6-7-20(21)34-13-23(32)11-24(26,27)12-23)29-14-28-30-10-16(8-19(30)22(29)31)15-2-4-17(25)5-3-15/h2-10,14,32H,11-13H2,1H3 LHIJZZNBPHAXFD-UHFFFAOYSA-N 50120675 CHEMBL3618339 Melanin-concentrating hormone receptor 1 Rattus 3.8 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120675 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120675&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45279061 319566004 CHEMBL3618339 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411543 CCS(=O)(=O)C[C@@H](O)COc1ccc(cc1OC)-n1cnn2cc(cc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C24H24ClN3O6S/c1-3-35(31,32)14-20(29)13-34-22-9-8-19(11-23(22)33-2)27-15-26-28-12-17(10-21(28)24(27)30)16-4-6-18(25)7-5-16/h4-12,15,20,29H,3,13-14H2,1-2H3/t20-/m0/s1 PVKJIGKULXILOD-FQEVSTJZSA-N 50120676 CHEMBL3618340 Melanin-concentrating hormone receptor 1 Rattus 1.5 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120676 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120676&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45279148 319566005 CHEMBL3618340 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411544 COc1cc(ccc1OCC(O)C1CC1)-n1cnn2cc(cc2c1=O)-c1ccc(Cl)cn1 InChI=1S/C23H21ClN4O4/c1-31-22-9-17(5-7-21(22)32-12-20(29)14-2-3-14)27-13-26-28-11-15(8-19(28)23(27)30)18-6-4-16(24)10-25-18/h4-11,13-14,20,29H,2-3,12H2,1H3 QKWXHKFUQHMBFV-UHFFFAOYSA-N 50120677 CHEMBL3618341 Melanin-concentrating hormone receptor 1 Rattus 12 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120677 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120677&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45279871 319566006 CHEMBL3618341 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411545 COc1cc(ccc1OC[C@H](O)C1CC1)-n1cnn2cc(cc2c1=O)-c1ccc(Cl)cn1 InChI=1S/C23H21ClN4O4/c1-31-22-9-17(5-7-21(22)32-12-20(29)14-2-3-14)27-13-26-28-11-15(8-19(28)23(27)30)18-6-4-16(24)10-25-18/h4-11,13-14,20,29H,2-3,12H2,1H3/t20-/m0/s1 QKWXHKFUQHMBFV-FQEVSTJZSA-N 50120678 CHEMBL3618342 Melanin-concentrating hormone receptor 1 Rattus 12 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120678 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120678&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45279064 319566007 CHEMBL3618342 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411546 COc1cc(ccc1N1CC[C@@H](O)C1)-n1cnn2cc(cc2c1=O)-c1ccc(Cl)cn1 InChI=1S/C22H20ClN5O3/c1-31-21-9-16(3-5-19(21)26-7-6-17(29)12-26)27-13-25-28-11-14(8-20(28)22(27)30)18-4-2-15(23)10-24-18/h2-5,8-11,13,17,29H,6-7,12H2,1H3/t17-/m1/s1 SKYSAAKSQGUHJV-QGZVFWFLSA-N 50120708 CHEMBL3618343 Melanin-concentrating hormone receptor 1 Rattus 9.6 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120708 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120708&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45279872 104013750 CHEMBL3618343 ZINC13491970 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411547 CCS(=O)(=O)C[C@@H](O)COc1ccc(cc1OC)-n1cnn2cc(cc2c1=O)-c1ccc(Cl)cn1 InChI=1S/C23H23ClN4O6S/c1-3-35(31,32)13-18(29)12-34-21-7-5-17(9-22(21)33-2)27-14-26-28-11-15(8-20(28)23(27)30)19-6-4-16(24)10-25-19/h4-11,14,18,29H,3,12-13H2,1-2H3/t18-/m0/s1 OSDRIYCMOIDAKM-SFHVURJKSA-N 50120716 CHEMBL3618344 Melanin-concentrating hormone receptor 1 Rattus 8.7 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120716 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120716&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45279321 104013758 CHEMBL3618344 ZINC13491969 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411548 COc1cc(ccc1OCC1(O)CC(F)(F)C1)-n1cnn2cc(cc2c1=O)-c1ccc(Cl)cn1 InChI=1S/C23H19ClF2N4O4/c1-33-20-7-16(3-5-19(20)34-12-22(32)10-23(25,26)11-22)29-13-28-30-9-14(6-18(30)21(29)31)17-4-2-15(24)8-27-17/h2-9,13,32H,10-12H2,1H3 KLJSSNMESFVMNT-UHFFFAOYSA-N 50120729 CHEMBL3618345 Melanin-concentrating hormone receptor 1 Rattus 6.5 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120729 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120729&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45279062 104013771 CHEMBL3618345 ZINC00008779 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411549 COc1cc(ccc1OCC(C)(C)O)-n1cnn2cc(cc2c1=O)-c1ncc(Cl)cn1 InChI=1S/C21H20ClN5O4/c1-21(2,29)11-31-17-5-4-15(7-18(17)30-3)26-12-25-27-10-13(6-16(27)20(26)28)19-23-8-14(22)9-24-19/h4-10,12,29H,11H2,1-3H3 VPDYEZOCBRNOPR-UHFFFAOYSA-N 50120732 CHEMBL3618346 Melanin-concentrating hormone receptor 1 Rattus 15 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120732 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120732&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45278578 104013774 CHEMBL3618346 ZINC00008847 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411550 COc1cc(ccc1OCC(O)C1CC1)-n1cnn2cc(cc2c1=O)-c1ncc(Cl)cn1 InChI=1S/C22H20ClN5O4/c1-31-20-7-16(4-5-19(20)32-11-18(29)13-2-3-13)27-12-26-28-10-14(6-17(28)22(27)30)21-24-8-15(23)9-25-21/h4-10,12-13,18,29H,2-3,11H2,1H3 YJRQMEMJIWBDAJ-UHFFFAOYSA-N 50120778 CHEMBL3618347 Melanin-concentrating hormone receptor 1 Rattus 15 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120778 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120778&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45278577 104013820 CHEMBL3618347 ZINC13492030 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411551 CCS(=O)(=O)C[C@@H](O)COc1ccc(cc1OC)-n1cnn2cc(cc2c1=O)-c1ncc(Cl)cn1 InChI=1S/C22H22ClN5O6S/c1-3-35(31,32)12-17(29)11-34-19-5-4-16(7-20(19)33-2)27-13-26-28-10-14(6-18(28)22(27)30)21-24-8-15(23)9-25-21/h4-10,13,17,29H,3,11-12H2,1-2H3/t17-/m0/s1 GCQMRTLJHLGXML-KRWDZBQOSA-N 50120784 CHEMBL3616496 Melanin-concentrating hormone receptor 1 Rattus 23 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120784&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45279319 104013826 CHEMBL3616496 ZINC13492035 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411552 COc1cc(ccc1OCC1(O)CC(F)(F)C1)-n1cnn2cc(cc2c1=O)-c1ncc(Cl)cn1 InChI=1S/C22H18ClF2N5O4/c1-33-18-5-15(2-3-17(18)34-11-21(32)9-22(24,25)10-21)29-12-28-30-8-13(4-16(30)20(29)31)19-26-6-14(23)7-27-19/h2-8,12,32H,9-11H2,1H3 TZNRMDWQKKCZGO-UHFFFAOYSA-N 50120787 CHEMBL3618348 Melanin-concentrating hormone receptor 1 Rattus 7.9 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120787&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45279233 104013829 CHEMBL3618348 ZINC13492061 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411553 COc1cc(ccc1OCC(C)O)-n1cnn2cc(cc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C22H20ClN3O4/c1-14(27)12-30-20-8-7-18(10-21(20)29-2)25-13-24-26-11-16(9-19(26)22(25)28)15-3-5-17(23)6-4-15/h3-11,13-14,27H,12H2,1-2H3 WBRMOXASXLNSBO-UHFFFAOYSA-N 50120796 CHEMBL3618363 Melanin-concentrating hormone receptor 1 Rattus 1.4 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120796&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45279867 104013838 CHEMBL3618363 ZINC13492060 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411554 COc1cc(ccc1OCCN1CCCC1)-n1cnn2cc(cc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C25H25ClN4O3/c1-32-24-15-21(8-9-23(24)33-13-12-28-10-2-3-11-28)29-17-27-30-16-19(14-22(30)25(29)31)18-4-6-20(26)7-5-18/h4-9,14-17H,2-3,10-13H2,1H3 GGKAJWOMSFBRSA-UHFFFAOYSA-N 50120624 CHEMBL3618324 Melanin-concentrating hormone receptor 1 Rattus 0.400000 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120624 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120624&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45279490 104013675 CHEMBL3618324 ZINC13819687 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411555 COc1ccc(cc1OC)-n1cnn2cc(nc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C19H15ClN4O3/c1-26-16-8-7-14(9-17(16)27-2)23-11-21-24-10-15(22-18(24)19(23)25)12-3-5-13(20)6-4-12/h3-11H,1-2H3 HEIDFIAUBSMMDH-UHFFFAOYSA-N 50120671 CHEMBL3618323 Melanin-concentrating hormone receptor 1 Rattus 87 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120671 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120671&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45278657 319566000 CHEMBL3618323 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411556 COc1ccc(cc1OC)-n1cnn2nc(cc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C19H15ClN4O3/c1-26-17-8-7-14(9-18(17)27-2)23-11-21-24-16(19(23)25)10-15(22-24)12-3-5-13(20)6-4-12/h3-11H,1-2H3 USBJXXZMWWDHDE-UHFFFAOYSA-N 50120672 CHEMBL3618322 Melanin-concentrating hormone receptor 1 Rattus 106 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120672 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120672&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45279491 319566001 CHEMBL3618322 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50411557 COc1ccc(cc1OC)-n1cnn2cc(cc2c1=O)-c1ccc(Cl)cc1 InChI=1S/C20H16ClN3O3/c1-26-18-8-7-16(10-19(18)27-2)23-12-22-24-11-14(9-17(24)20(23)25)13-3-5-15(21)6-4-13/h3-12H,1-2H3 IJWHKIFJJYGLFL-UHFFFAOYSA-N 50120673 CHEMBL3618321 Melanin-concentrating hormone receptor 1 Rattus 8.0 ChEMBL 10.1016/j.bmcl.2015.09.018 10.7270/Q2JD4ZMW 26386604 Devasthale, P; Wang, W; Mignone, J; Renduchintala, K; Radhakrishnan, S; Dhanapal, J; Selvaraj, J; Kuppusamy, R; Pelleymounter, MA; Longhi, D; Huang, N; Flynn, N; Azzara, AV; Rohrbach, K; Devenny, J; Rooney, S; Thomas, M; Glick, S; Godonis, H; Harvey, S; Cullen, MJ; Zhang, H; Caporuscio, C; Stetsko, P; Grubb, M; Huang, C; Zhang, L; Freeden, C; Murphy, BJ; Robl, JA; Washburn, WN Bristol-Myers Squibb Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120673 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120673&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45279488 319566002 CHEMBL3618321 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471576 Cc1c(CC#N)nc2ccc(cn12)-n1ccc(OCc2ccc(F)cc2)cc1=O InChI=1S/C22H17FN4O2/c1-15-20(8-10-24)25-21-7-6-18(13-27(15)21)26-11-9-19(12-22(26)28)29-14-16-2-4-17(23)5-3-16/h2-7,9,11-13H,8,14H2,1H3 GBEKQHJQGUQKCW-UHFFFAOYSA-N 50149033 CHEMBL3769758 Melanin-concentrating hormone receptor 1 Rattus 170 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149033&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44348128 104037193 CHEMBL3769758 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471577 Cc1c(nc2ccc(cn12)-n1ccc(OCc2ccccn2)cc1=O)C1CC1 InChI=1S/C22H20N4O2/c1-15-22(16-5-6-16)24-20-8-7-18(13-26(15)20)25-11-9-19(12-21(25)27)28-14-17-4-2-3-10-23-17/h2-4,7-13,16H,5-6,14H2,1H3 BMRXFTJAMFWTLI-UHFFFAOYSA-N 50149295 CHEMBL3769682 Melanin-concentrating hormone receptor 1 Rattus 150 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149295 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149295&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44344538 85486145 CHEMBL3769682 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471578 Cc1c(nc2ccc(cn12)-n1ccc(OCc2cccnc2)cc1=O)C1CC1 InChI=1S/C22H20N4O2/c1-15-22(17-4-5-17)24-20-7-6-18(13-26(15)20)25-10-8-19(11-21(25)27)28-14-16-3-2-9-23-12-16/h2-3,6-13,17H,4-5,14H2,1H3 ZLWNDZOYYURDLP-UHFFFAOYSA-N 50149405 CHEMBL3770454 Melanin-concentrating hormone receptor 1 Rattus >1000 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149405 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149405&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44346293 104037550 29067 CHEMBL3770454 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471609 Cc1c(nc2ccc(cn12)-n1ccc(Oc2ccc(OC(F)(F)F)cc2)cc1=O)C1CC1 InChI=1S/C23H18F3N3O3/c1-14-22(15-2-3-15)27-20-9-4-16(13-29(14)20)28-11-10-19(12-21(28)30)31-17-5-7-18(8-6-17)32-23(24,25)26/h4-13,15H,2-3H2,1H3 GCJDMMOKYRCMEN-UHFFFAOYSA-N 50149452 CHEMBL3769964 Melanin-concentrating hormone receptor 1 Rattus 950 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149452 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149452&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45261697 92733714 CHEMBL3769964 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471610 Cc1c(nc2ccc(cn12)-n1cccc(OCc2ccc(Cl)cc2)c1=O)C1CC1 InChI=1S/C23H20ClN3O2/c1-15-22(17-6-7-17)25-21-11-10-19(13-27(15)21)26-12-2-3-20(23(26)28)29-14-16-4-8-18(24)9-5-16/h2-5,8-13,17H,6-7,14H2,1H3 ZBAKJZGMBKZSHX-UHFFFAOYSA-N 50149451 CHEMBL3771133 Melanin-concentrating hormone receptor 1 Rattus 650 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149451 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149451&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45261709 92733728 CHEMBL3771133 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471611 Cc1c(nc2ccc(cn12)-n1cccc(Oc2ccc(OC(F)(F)F)cc2)c1=O)C1CC1 InChI=1S/C23H18F3N3O3/c1-14-21(15-4-5-15)27-20-11-6-16(13-29(14)20)28-12-2-3-19(22(28)30)31-17-7-9-18(10-8-17)32-23(24,25)26/h2-3,6-13,15H,4-5H2,1H3 HNLYYLZMISIJNO-UHFFFAOYSA-N 50149450 CHEMBL3770776 Melanin-concentrating hormone receptor 1 Rattus 240 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149450 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149450&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45261771 92733810 CHEMBL3770776 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471612 Cc1c(nc2ccc(cn12)-n1ncc(OCc2ccc(Cl)cc2)cc1=O)C1CC1 InChI=1S/C22H19ClN4O2/c1-14-22(16-4-5-16)25-20-9-8-18(12-26(14)20)27-21(28)10-19(11-24-27)29-13-15-2-6-17(23)7-3-15/h2-3,6-12,16H,4-5,13H2,1H3 FJGMABCRRDYEAM-UHFFFAOYSA-N 50149449 CHEMBL3770135 Melanin-concentrating hormone receptor 1 Rattus 110 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149449 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149449&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45261790 92733834 CHEMBL3770135 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471613 Cc1c(nc2ccc(cn12)-n1cnc(OCc2ccc(Cl)cc2)cc1=O)C1CC1 InChI=1S/C22H19ClN4O2/c1-14-22(16-4-5-16)25-19-9-8-18(11-26(14)19)27-13-24-20(10-21(27)28)29-12-15-2-6-17(23)7-3-15/h2-3,6-11,13,16H,4-5,12H2,1H3 VZHNRUAJJOZQFL-UHFFFAOYSA-N 50149448 CHEMBL3769460 Melanin-concentrating hormone receptor 1 Rattus 140 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149448&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45264994 92738715 CHEMBL3769460 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471614 Cc1c(nc2ccc(cn12)-n1ccc(OCc2ccc(Cl)cc2)nc1=O)C1CC1 InChI=1S/C22H19ClN4O2/c1-14-21(16-4-5-16)24-19-9-8-18(12-27(14)19)26-11-10-20(25-22(26)28)29-13-15-2-6-17(23)7-3-15/h2-3,6-12,16H,4-5,13H2,1H3 AYMBXRGUDOEASY-UHFFFAOYSA-N 50149447 CHEMBL3769550 Melanin-concentrating hormone receptor 1 Rattus 30 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149447 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149447&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45261784 92733827 CHEMBL3769550 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471615 Cc1c(nc2ccc(cn12)-n1cc(C)c(OCc2ccc(Cl)cc2)cc1=O)C1CC1 InChI=1S/C24H22ClN3O2/c1-15-12-28(23(29)11-21(15)30-14-17-3-7-19(25)8-4-17)20-9-10-22-26-24(18-5-6-18)16(2)27(22)13-20/h3-4,7-13,18H,5-6,14H2,1-2H3 KMILLQAPTCJKSV-UHFFFAOYSA-N 50149446 CHEMBL3770175 Melanin-concentrating hormone receptor 1 Rattus 150 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149446 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149446&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44332876 85460240 CHEMBL3770175 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471616 Cc1c(nc2ccc(cn12)-n1ccc2OC(CCc2c1=O)c1ccc(Cl)cc1)C1CC1 InChI=1S/C25H22ClN3O2/c1-15-24(17-2-3-17)27-23-11-8-19(14-29(15)23)28-13-12-22-20(25(28)30)9-10-21(31-22)16-4-6-18(26)7-5-16/h4-8,11-14,17,21H,2-3,9-10H2,1H3 VXIZWVWATYEQCA-UHFFFAOYSA-N 50149445 CHEMBL3770680 Melanin-concentrating hormone receptor 1 Rattus 62 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149445&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11739527 85492604 CHEMBL3770680 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471617 Cc1c(nc2ccc(cn12)-n1ccc2oc(cc2c1=O)-c1ccc(Cl)cc1)C1CC1 InChI=1S/C24H18ClN3O2/c1-14-23(16-2-3-16)26-22-9-8-18(13-28(14)22)27-11-10-20-19(24(27)29)12-21(30-20)15-4-6-17(25)7-5-15/h4-13,16H,2-3H2,1H3 FBRSISPMXWGFQN-UHFFFAOYSA-N 50149444 CHEMBL3770706 Melanin-concentrating hormone receptor 1 Rattus 11 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149444 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149444&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11199029 85492568 CHEMBL3770706 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471618 Cc1c(nc2ccc(cn12)-n1ccc(OCc2ccc(Br)cc2)cc1=O)C1CC1 InChI=1S/C23H20BrN3O2/c1-15-23(17-4-5-17)25-21-9-8-19(13-27(15)21)26-11-10-20(12-22(26)28)29-14-16-2-6-18(24)7-3-16/h2-3,6-13,17H,4-5,14H2,1H3 CLSPCTXAOINBRJ-UHFFFAOYSA-N 50149443 CHEMBL3771307 Melanin-concentrating hormone receptor 1 Rattus 9.3 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149443 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149443&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 9975423 85492513 CHEMBL3771307 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471619 CC(C)c1ccc(COc2ccn(-c3ccc4nc(C5CC5)c(C)n4c3)c(=O)c2)cc1 InChI=1S/C26H27N3O2/c1-17(2)20-6-4-19(5-7-20)16-31-23-12-13-28(25(30)14-23)22-10-11-24-27-26(21-8-9-21)18(3)29(24)15-22/h4-7,10-15,17,21H,8-9,16H2,1-3H3 GDZWHMKDWTYIGC-UHFFFAOYSA-N 50149442 CHEMBL3769899 Melanin-concentrating hormone receptor 1 Rattus 240 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149442 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149442&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44347077 85492571 CHEMBL3769899 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471620 Cc1c(nc2ccc(cn12)-n1ccc(OCc2ccc(cc2)C(F)(F)F)cc1=O)C1CC1 InChI=1S/C24H20F3N3O2/c1-15-23(17-4-5-17)28-21-9-8-19(13-30(15)21)29-11-10-20(12-22(29)31)32-14-16-2-6-18(7-3-16)24(25,26)27/h2-3,6-13,17H,4-5,14H2,1H3 MJVYVVPFULMISW-UHFFFAOYSA-N 50149441 CHEMBL3770865 Melanin-concentrating hormone receptor 1 Rattus 82 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149441 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149441&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10247814 85492606 CHEMBL3770865 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471621 Cc1nc2ccc(cn2c1C)-n1ccc(OCc2ccccc2)cc1=O InChI=1S/C21H19N3O2/c1-15-16(2)24-13-18(8-9-20(24)22-15)23-11-10-19(12-21(23)25)26-14-17-6-4-3-5-7-17/h3-13H,14H2,1-2H3 RJKZNJBGSQNFNP-UHFFFAOYSA-N 50149440 CHEMBL3769585 Melanin-concentrating hormone receptor 1 Rattus 80 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149440 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149440&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11485139 85492512 CHEMBL3769585 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471622 CCc1nc2ccc(cn2c1C)-n1ccc(OCc2ccccc2)cc1=O InChI=1S/C22H21N3O2/c1-3-20-16(2)25-14-18(9-10-21(25)23-20)24-12-11-19(13-22(24)26)27-15-17-7-5-4-6-8-17/h4-14H,3,15H2,1-2H3 ALVCBZKUFZQTBZ-UHFFFAOYSA-N 50149439 CHEMBL3771000 Melanin-concentrating hormone receptor 1 Rattus 120 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149439 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149439&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11371348 85492230 CHEMBL3771000 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471623 Cc1c(nc2ccc(cn12)-n1ccc(OCc2ccc(F)cc2)cc1=O)C#N InChI=1S/C21H15FN4O2/c1-14-19(11-23)24-20-7-6-17(12-26(14)20)25-9-8-18(10-21(25)27)28-13-15-2-4-16(22)5-3-15/h2-10,12H,13H2,1H3 PYQMXUZVYLCRAF-UHFFFAOYSA-N 50149438 CHEMBL3769670 Melanin-concentrating hormone receptor 1 Rattus >1000 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149438 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149438&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11462494 85492514 CHEMBL3769670 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471624 CN(C)C(=O)c1nc2ccc(cn2c1C)-n1ccc(OCc2ccc(F)cc2)cc1=O InChI=1S/C23H21FN4O3/c1-15-22(23(30)26(2)3)25-20-9-8-18(13-28(15)20)27-11-10-19(12-21(27)29)31-14-16-4-6-17(24)7-5-16/h4-13H,14H2,1-3H3 HHTBYGXDFXXNAF-UHFFFAOYSA-N 50149437 CHEMBL3770850 Melanin-concentrating hormone receptor 1 Rattus >1000 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149437 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149437&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44347402 85493341 CHEMBL3770850 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471625 CC(=O)c1nc2ccc(cn2c1C)-n1ccc(OCc2ccc(F)cc2)cc1=O InChI=1S/C22H18FN3O3/c1-14-22(15(2)27)24-20-8-7-18(12-26(14)20)25-10-9-19(11-21(25)28)29-13-16-3-5-17(23)6-4-16/h3-12H,13H2,1-2H3 OOARKYPMMJPUHX-UHFFFAOYSA-N 50149436 CHEMBL3770750 Melanin-concentrating hormone receptor 1 Rattus >1000 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149436 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149436&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44346963 85492333 CHEMBL3770750 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471626 Cc1c(nc2ccc(cn12)-n1ccc(OCc2ccc(F)cc2)cc1=O)C(=O)C1CC1 InChI=1S/C24H20FN3O3/c1-15-23(24(30)17-4-5-17)26-21-9-8-19(13-28(15)21)27-11-10-20(12-22(27)29)31-14-16-2-6-18(25)7-3-16/h2-3,6-13,17H,4-5,14H2,1H3 BXXXYZIOUUHSOK-UHFFFAOYSA-N 50149435 CHEMBL3769816 Melanin-concentrating hormone receptor 1 Rattus >1000 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149435 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149435&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44346983 85492369 CHEMBL3769816 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471627 Cc1c(CO)nc2ccc(cn12)-n1ccc(OCc2ccc(F)cc2)cc1=O InChI=1S/C21H18FN3O3/c1-14-19(12-26)23-20-7-6-17(11-25(14)20)24-9-8-18(10-21(24)27)28-13-15-2-4-16(22)5-3-15/h2-11,26H,12-13H2,1H3 ZEXADDNSAAAMIR-UHFFFAOYSA-N 50149434 CHEMBL3770539 Melanin-concentrating hormone receptor 1 Rattus >1000 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149434 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149434&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11748958 85492473 CHEMBL3770539 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471628 COCc1nc2ccc(cn2c1C)-n1ccc(OCc2ccc(F)cc2)cc1=O InChI=1S/C22H20FN3O3/c1-15-20(14-28-2)24-21-8-7-18(12-26(15)21)25-10-9-19(11-22(25)27)29-13-16-3-5-17(23)6-4-16/h3-12H,13-14H2,1-2H3 PGMOJCYFFDPZRD-UHFFFAOYSA-N 50149409 CHEMBL3770348 Melanin-concentrating hormone receptor 1 Rattus >1000 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149409 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149409&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 9968587 85454132 CHEMBL3770348 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471629 Cc1c(nc2ccc(cn12)-n1ccc(OCc2ccc(Cl)cc2)cc1=O)C1CC1 InChI=1S/C23H20ClN3O2/c1-15-23(17-4-5-17)25-21-9-8-19(13-27(15)21)26-11-10-20(12-22(26)28)29-14-16-2-6-18(24)7-3-16/h2-3,6-13,17H,4-5,14H2,1H3 LAMBIBHLZLVLFX-UHFFFAOYSA-N 50149453 CHEMBL3770359 Melanin-concentrating hormone receptor 1 Rattus 20 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149453&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44346769 85491907 CHEMBL3770359 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471630 Cc1oc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cc2c1C InChI=1S/C19H16F3NO4/c1-11-12(2)26-17-8-3-13(9-16(11)17)23-18(24)10-25-14-4-6-15(7-5-14)27-19(20,21)22/h3-9H,10H2,1-2H3,(H,23,24) DGZDPCUJTJWYIU-UHFFFAOYSA-N 50149454 CHEMBL3769548 Melanin-concentrating hormone receptor 1 Rattus >1000 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149454 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149454&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45264999 92738722 CHEMBL3769548 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471631 Cc1c(cc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cn12)C1CC1 InChI=1S/C21H19F3N2O3/c1-13-19(14-2-3-14)10-16-5-4-15(11-26(13)16)25-20(27)12-28-17-6-8-18(9-7-17)29-21(22,23)24/h4-11,14H,2-3,12H2,1H3,(H,25,27) VTXQTDBKNILZTB-UHFFFAOYSA-N 50149455 CHEMBL3769838 Melanin-concentrating hormone receptor 1 Rattus >1000 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149455 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149455&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45261705 92733724 CHEMBL3769838 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471632 Cc1c(nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cn12)C1CC1 InChI=1S/C20H18F3N3O3/c1-12-19(13-2-3-13)25-17-9-4-14(10-26(12)17)24-18(27)11-28-15-5-7-16(8-6-15)29-20(21,22)23/h4-10,13H,2-3,11H2,1H3,(H,24,27) KFXPJPDEXBORLL-UHFFFAOYSA-N 50149456 CHEMBL3769702 Melanin-concentrating hormone receptor 1 Rattus 6.3 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149456&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45261708 92733727 CHEMBL3769702 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471633 Cc1nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cn2c1C InChI=1S/C18H16F3N3O3/c1-11-12(2)24-9-13(3-8-16(24)22-11)23-17(25)10-26-14-4-6-15(7-5-14)27-18(19,20)21/h3-9H,10H2,1-2H3,(H,23,25) DIZOQNXEOQHGSR-UHFFFAOYSA-N 50149457 CHEMBL3771335 Melanin-concentrating hormone receptor 1 Rattus 7.8 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149457 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149457&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45261721 92733744 CHEMBL3771335 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471641 Cc1c(nc2ccc(cn12)-n1ccc(OCc2ccncc2)cc1=O)C1CC1 InChI=1S/C22H20N4O2/c1-15-22(17-2-3-17)24-20-5-4-18(13-26(15)20)25-11-8-19(12-21(25)27)28-14-16-6-9-23-10-7-16/h4-13,17H,2-3,14H2,1H3 CXWXKURWVRBSPN-UHFFFAOYSA-N 50149407 CHEMBL3769928 Melanin-concentrating hormone receptor 1 Rattus >1000 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149407 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149407&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10216120 85491685 CHEMBL3769928 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471642 Cc1c(nc2ccc(cn12)-n1ccc(OCc2cncnc2)cc1=O)C1CC1 InChI=1S/C21H19N5O2/c1-14-21(16-2-3-16)24-19-5-4-17(11-26(14)19)25-7-6-18(8-20(25)27)28-12-15-9-22-13-23-10-15/h4-11,13,16H,2-3,12H2,1H3 KAIDMJVKSRKNRB-UHFFFAOYSA-N 50149406 CHEMBL3770975 Melanin-concentrating hormone receptor 1 Rattus >1000 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149406 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149406&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44346295 104037551 CHEMBL3770975 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471643 Cc1c(nc2ccc(cn12)-n1ccc(OCc2cccs2)cc1=O)C1CC1 InChI=1S/C21H19N3O2S/c1-14-21(15-4-5-15)22-19-7-6-16(12-24(14)19)23-9-8-17(11-20(23)25)26-13-18-3-2-10-27-18/h2-3,6-12,15H,4-5,13H2,1H3 UMRRNSMTKIQNLN-UHFFFAOYSA-N 50149464 CHEMBL3771336 Melanin-concentrating hormone receptor 1 Rattus 130 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149464 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149464&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45261689 92733705 CHEMBL3771336 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471644 Cc1c(nc2ccc(cn12)-n1ccc(OCc2ccsc2)cc1=O)C1CC1 InChI=1S/C21H19N3O2S/c1-14-21(16-2-3-16)22-19-5-4-17(11-24(14)19)23-8-6-18(10-20(23)25)26-12-15-7-9-27-13-15/h4-11,13,16H,2-3,12H2,1H3 VGYNMKFQIYMUTO-UHFFFAOYSA-N 50149463 CHEMBL3769582 Melanin-concentrating hormone receptor 1 Rattus 54 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149463 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149463&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44347151 85492784 CHEMBL3769582 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471645 Cc1c(nc2ccc(cn12)-n1ccc(OCc2csc(Cl)c2)cc1=O)C1CC1 InChI=1S/C21H18ClN3O2S/c1-13-21(15-2-3-15)23-19-5-4-16(10-25(13)19)24-7-6-17(9-20(24)26)27-11-14-8-18(22)28-12-14/h4-10,12,15H,2-3,11H2,1H3 QNVFWMGJWHJVJJ-UHFFFAOYSA-N 50149462 CHEMBL3771182 Melanin-concentrating hormone receptor 1 Rattus 7.5 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149462&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45261698 92733715 CHEMBL3771182 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471646 Cc1c(nc2ccc(cn12)-n1ccc(OCc2csc(c2)C(F)(F)F)cc1=O)C1CC1 InChI=1S/C22H18F3N3O2S/c1-13-21(15-2-3-15)26-19-5-4-16(10-28(13)19)27-7-6-17(9-20(27)29)30-11-14-8-18(31-12-14)22(23,24)25/h4-10,12,15H,2-3,11H2,1H3 NLPCPCSIZQPIFR-UHFFFAOYSA-N 50149461 CHEMBL3769762 Melanin-concentrating hormone receptor 1 Rattus 15 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149461 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149461&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45261716 92733736 CHEMBL3769762 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471647 Cc1c(nc2ccc(cn12)-n1ccc(OCc2ccccc2)cc1=O)C1CC1 InChI=1S/C23H21N3O2/c1-16-23(18-7-8-18)24-21-10-9-19(14-26(16)21)25-12-11-20(13-22(25)27)28-15-17-5-3-2-4-6-17/h2-6,9-14,18H,7-8,15H2,1H3 KDYGMWSJUSTGHL-UHFFFAOYSA-N 50149460 CHEMBL3770954 Melanin-concentrating hormone receptor 1 Rattus 28 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149460&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45261700 92733717 CHEMBL3770954 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471648 Cc1c(nc2ccc(cn12)-n1ccc(OCc2ccc(F)cc2)cc1=O)C1CC1 InChI=1S/C23H20FN3O2/c1-15-23(17-4-5-17)25-21-9-8-19(13-27(15)21)26-11-10-20(12-22(26)28)29-14-16-2-6-18(24)7-3-16/h2-3,6-13,17H,4-5,14H2,1H3 WFPDMXVDRXWKMF-UHFFFAOYSA-N 50149459 CHEMBL3769602 Melanin-concentrating hormone receptor 1 Rattus 28 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149459&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11211090 85492819 CHEMBL3769602 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50471649 Cc1c(nc2ccc(cn12)-n1ccc(OCc2ccc(Cl)cn2)cc1=O)C1CC1 InChI=1S/C22H19ClN4O2/c1-14-22(15-2-3-15)25-20-7-6-18(12-27(14)20)26-9-8-19(10-21(26)28)29-13-17-5-4-16(23)11-24-17/h4-12,15H,2-3,13H2,1H3 NCFYEEMYLICQLF-UHFFFAOYSA-N 50149458 CHEMBL3770396 Melanin-concentrating hormone receptor 1 Rattus 19 ChEMBL 10.1021/acs.jmedchem.5b01704 10.7270/Q2V40X2T 26736071 Igawa, H; Takahashi, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Kawata, Y; Ashina, S; Yamamoto, S; Kundu, M; Khamrai, U; Hirabayashi, H; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50149458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50149458&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45265028 92738765 CHEMBL3770396 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490457 Cn1c(nc2ccc(cc12)-n1ccc(OCc2csc(c2)C(F)(F)F)cc1=O)C1CC1 InChI=1S/C22H18F3N3O2S/c1-27-18-9-15(4-5-17(18)26-21(27)14-2-3-14)28-7-6-16(10-20(28)29)30-11-13-8-19(31-12-13)22(23,24)25/h4-10,12,14H,2-3,11H2,1H3 FXCYREGHIBLSLY-UHFFFAOYSA-N 50163470 CHEMBL3794150 Melanin-concentrating hormone receptor 1 Rattus 29 ChEMBL 10.1016/j.bmc.2016.04.011 10.7270/Q2862JB1 27112449 Igawa, H; Takahashi, M; Shirasaki, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Okuda, S; Kawata, Y; Noguchi, T; Yamamoto, S; Fujioka, Y; Kundu, M; Khamrai, U; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163470&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 89691065 104049470 CHEMBL3794150 ZINC28111887 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490458 Cn1c(nc2ccc(cc12)-n1ccc(OCc2cc(cs2)C(F)(F)F)cc1=O)C1CC1 InChI=1S/C22H18F3N3O2S/c1-27-19-9-15(4-5-18(19)26-21(27)13-2-3-13)28-7-6-16(10-20(28)29)30-11-17-8-14(12-31-17)22(23,24)25/h4-10,12-13H,2-3,11H2,1H3 SYIKYRIFRAHNPB-UHFFFAOYSA-N 50163467 CHEMBL3792697 Melanin-concentrating hormone receptor 1 Rattus 17 ChEMBL 10.1016/j.bmc.2016.04.011 10.7270/Q2862JB1 27112449 Igawa, H; Takahashi, M; Shirasaki, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Okuda, S; Kawata, Y; Noguchi, T; Yamamoto, S; Fujioka, Y; Kundu, M; Khamrai, U; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163467&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 89690957 104049467 CHEMBL3792697 ZINC28105664 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490465 Cn1c(nc2ccc(cc12)-n1ccc(OCc2ccc(Cl)s2)cc1=O)C1CC1 InChI=1S/C21H18ClN3O2S/c1-24-18-10-14(4-6-17(18)23-21(24)13-2-3-13)25-9-8-15(11-20(25)26)27-12-16-5-7-19(22)28-16/h4-11,13H,2-3,12H2,1H3 RPFBZAHRSRZYGF-UHFFFAOYSA-N 50163476 CHEMBL3792516 Melanin-concentrating hormone receptor 1 Rattus 11 ChEMBL 10.1016/j.bmc.2016.04.011 10.7270/Q2862JB1 27112449 Igawa, H; Takahashi, M; Shirasaki, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Okuda, S; Kawata, Y; Noguchi, T; Yamamoto, S; Fujioka, Y; Kundu, M; Khamrai, U; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163476 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163476&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 89702226 104049476 CHEMBL3792516 ZINC28115567 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490466 Cn1c(nc2ccc(cc12)-n1ccc(OCc2ccsc2)cc1=O)C1CC1 InChI=1S/C21H19N3O2S/c1-23-19-10-16(4-5-18(19)22-21(23)15-2-3-15)24-8-6-17(11-20(24)25)26-12-14-7-9-27-13-14/h4-11,13,15H,2-3,12H2,1H3 MQQLRZBKRHUHQC-UHFFFAOYSA-N 50163492 CHEMBL3793111 Melanin-concentrating hormone receptor 1 Rattus 29 ChEMBL 10.1016/j.bmc.2016.04.011 10.7270/Q2862JB1 27112449 Igawa, H; Takahashi, M; Shirasaki, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Okuda, S; Kawata, Y; Noguchi, T; Yamamoto, S; Fujioka, Y; Kundu, M; Khamrai, U; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163492 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163492&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 89691162 104049492 CHEMBL3793111 ZINC28115560 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490467 Cn1c(nc2ccc(cc12)-n1ccc(OCc2cccs2)cc1=O)C1CC1 InChI=1S/C21H19N3O2S/c1-23-19-11-15(6-7-18(19)22-21(23)14-4-5-14)24-9-8-16(12-20(24)25)26-13-17-3-2-10-27-17/h2-3,6-12,14H,4-5,13H2,1H3 YEJHUJQPWPLYSR-UHFFFAOYSA-N 50163488 CHEMBL3793343 Melanin-concentrating hormone receptor 1 Rattus 120 ChEMBL 10.1016/j.bmc.2016.04.011 10.7270/Q2862JB1 27112449 Igawa, H; Takahashi, M; Shirasaki, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Okuda, S; Kawata, Y; Noguchi, T; Yamamoto, S; Fujioka, Y; Kundu, M; Khamrai, U; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163488 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163488&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 89691019 104049488 CHEMBL3793343 ZINC28112105 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490469 Cn1c(nc2ccc(cc12)-n1ccc(OCc2ncc(Cl)cn2)cc1=O)C1CC1 InChI=1S/C21H18ClN5O2/c1-26-18-8-15(4-5-17(18)25-21(26)13-2-3-13)27-7-6-16(9-20(27)28)29-12-19-23-10-14(22)11-24-19/h4-11,13H,2-3,12H2,1H3 PXAWPPAFKPIMFE-UHFFFAOYSA-N 50163485 CHEMBL3794445 Melanin-concentrating hormone receptor 1 Rattus 900 ChEMBL 10.1016/j.bmc.2016.04.011 10.7270/Q2862JB1 27112449 Igawa, H; Takahashi, M; Shirasaki, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Okuda, S; Kawata, Y; Noguchi, T; Yamamoto, S; Fujioka, Y; Kundu, M; Khamrai, U; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163485 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163485&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 89691264 104049485 CHEMBL3794445 ZINC28116387 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490470 Cn1c(nc2ccc(cc12)-n1ccc(OCc2ccc(Cl)cn2)cc1=O)C1CC1 InChI=1S/C22H19ClN4O2/c1-26-20-10-17(6-7-19(20)25-22(26)14-2-3-14)27-9-8-18(11-21(27)28)29-13-16-5-4-15(23)12-24-16/h4-12,14H,2-3,13H2,1H3 PPVWKZWUSNETPC-UHFFFAOYSA-N 50163482 CHEMBL3793989 Melanin-concentrating hormone receptor 1 Rattus 47 ChEMBL 10.1016/j.bmc.2016.04.011 10.7270/Q2862JB1 27112449 Igawa, H; Takahashi, M; Shirasaki, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Okuda, S; Kawata, Y; Noguchi, T; Yamamoto, S; Fujioka, Y; Kundu, M; Khamrai, U; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163482 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163482&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 89691144 104049482 CHEMBL3793989 ZINC28117036 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490471 Cn1c(nc2ccc(cc12)-n1ccc(OCc2ccccc2Cl)cc1=O)C1CC1 InChI=1S/C23H20ClN3O2/c1-26-21-12-17(8-9-20(21)25-23(26)15-6-7-15)27-11-10-18(13-22(27)28)29-14-16-4-2-3-5-19(16)24/h2-5,8-13,15H,6-7,14H2,1H3 JHYUZNZTYUQMSZ-UHFFFAOYSA-N 50163496 CHEMBL3793051 Melanin-concentrating hormone receptor 1 Rattus 140 ChEMBL 10.1016/j.bmc.2016.04.011 10.7270/Q2862JB1 27112449 Igawa, H; Takahashi, M; Shirasaki, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Okuda, S; Kawata, Y; Noguchi, T; Yamamoto, S; Fujioka, Y; Kundu, M; Khamrai, U; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163496 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163496&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 89690973 104049496 CHEMBL3793051 ZINC28118135 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490472 Cn1c(nc2ccc(cc12)-n1ccc(OCc2cccc(Cl)c2)cc1=O)C1CC1 InChI=1S/C23H20ClN3O2/c1-26-21-12-18(7-8-20(21)25-23(26)16-5-6-16)27-10-9-19(13-22(27)28)29-14-15-3-2-4-17(24)11-15/h2-4,7-13,16H,5-6,14H2,1H3 HFPZFKUFZLYAAA-UHFFFAOYSA-N 50163495 CHEMBL3792529 Melanin-concentrating hormone receptor 1 Rattus 72 ChEMBL 10.1016/j.bmc.2016.04.011 10.7270/Q2862JB1 27112449 Igawa, H; Takahashi, M; Shirasaki, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Okuda, S; Kawata, Y; Noguchi, T; Yamamoto, S; Fujioka, Y; Kundu, M; Khamrai, U; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163495&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 89691143 104049495 CHEMBL3792529 ZINC28113116 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490473 Cn1c(nc2ccc(cc12)-n1ccc(OCc2ccc(s2)C(F)(F)F)cc1=O)C1CC1 InChI=1S/C22H18F3N3O2S/c1-27-18-10-14(4-6-17(18)26-21(27)13-2-3-13)28-9-8-15(11-20(28)29)30-12-16-5-7-19(31-16)22(23,24)25/h4-11,13H,2-3,12H2,1H3 NUGRQANZYOOAIA-UHFFFAOYSA-N 50163481 CHEMBL3794306 Melanin-concentrating hormone receptor 1 Rattus 13 ChEMBL 10.1016/j.bmc.2016.04.011 10.7270/Q2862JB1 27112449 Igawa, H; Takahashi, M; Shirasaki, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Okuda, S; Kawata, Y; Noguchi, T; Yamamoto, S; Fujioka, Y; Kundu, M; Khamrai, U; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163481 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163481&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 89691096 104049481 CHEMBL3794306 ZINC28116648 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490474 Cn1c(nc2ccc(cc12)-n1ccc(OCc2csc(Cl)c2)cc1=O)C1CC1 InChI=1S/C21H18ClN3O2S/c1-24-18-9-15(4-5-17(18)23-21(24)14-2-3-14)25-7-6-16(10-20(25)26)27-11-13-8-19(22)28-12-13/h4-10,12,14H,2-3,11H2,1H3 PRHUPCKPZSORHL-UHFFFAOYSA-N 50163480 CHEMBL3792707 Melanin-concentrating hormone receptor 1 Rattus 9.3 ChEMBL 10.1016/j.bmc.2016.04.011 10.7270/Q2862JB1 27112449 Igawa, H; Takahashi, M; Shirasaki, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Okuda, S; Kawata, Y; Noguchi, T; Yamamoto, S; Fujioka, Y; Kundu, M; Khamrai, U; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163480&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 89702566 104049480 CHEMBL3792707 ZINC28115750 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490475 Cn1c(nc2ccc(cc12)-n1ccc(OCc2cc(Cl)cs2)cc1=O)C1CC1 InChI=1S/C21H18ClN3O2S/c1-24-19-9-15(4-5-18(19)23-21(24)13-2-3-13)25-7-6-16(10-20(25)26)27-11-17-8-14(22)12-28-17/h4-10,12-13H,2-3,11H2,1H3 XXAWNJXZMKQLSK-UHFFFAOYSA-N 50163478 CHEMBL3794345 Melanin-concentrating hormone receptor 1 Rattus 18 ChEMBL 10.1016/j.bmc.2016.04.011 10.7270/Q2862JB1 27112449 Igawa, H; Takahashi, M; Shirasaki, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Okuda, S; Kawata, Y; Noguchi, T; Yamamoto, S; Fujioka, Y; Kundu, M; Khamrai, U; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163478 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163478&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 89691044 104049478 CHEMBL3794345 ZINC28117331 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490479 Cn1c(CC2CC2)nc2ccc(cc12)-n1ccc(OCc2ccc(F)cc2)cc1=O InChI=1S/C24H22FN3O2/c1-27-22-13-19(8-9-21(22)26-23(27)12-16-2-3-16)28-11-10-20(14-24(28)29)30-15-17-4-6-18(25)7-5-17/h4-11,13-14,16H,2-3,12,15H2,1H3 ONWWTUSCDNWRTD-UHFFFAOYSA-N 50161848 CHEMBL3793827 Melanin-concentrating hormone receptor 1 Rattus 140 ChEMBL 10.1016/j.bmc.2016.04.011 10.7270/Q2862JB1 27112449 Igawa, H; Takahashi, M; Shirasaki, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Okuda, S; Kawata, Y; Noguchi, T; Yamamoto, S; Fujioka, Y; Kundu, M; Khamrai, U; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161848 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161848&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 89691284 341096920 CHEMBL3793827 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490480 Cn1c(nc2ccc(cc12)-n1ccc(OCc2ccc(F)cc2)cc1=O)C1CCCC1 InChI=1S/C25H24FN3O2/c1-28-23-14-20(10-11-22(23)27-25(28)18-4-2-3-5-18)29-13-12-21(15-24(29)30)31-16-17-6-8-19(26)9-7-17/h6-15,18H,2-5,16H2,1H3 AEPAWRLGXMNLFZ-UHFFFAOYSA-N 50161847 CHEMBL3793395 Melanin-concentrating hormone receptor 1 Rattus 460 ChEMBL 10.1016/j.bmc.2016.04.011 10.7270/Q2862JB1 27112449 Igawa, H; Takahashi, M; Shirasaki, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Okuda, S; Kawata, Y; Noguchi, T; Yamamoto, S; Fujioka, Y; Kundu, M; Khamrai, U; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161847&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 89691216 104048136 CHEMBL3793395 ZINC13609385 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490482 Cn1c(nc2ccc(cc12)-n1ccc(OCc2ccc(F)cc2)cc1=O)C1CCC1 InChI=1S/C24H22FN3O2/c1-27-22-13-19(9-10-21(22)26-24(27)17-3-2-4-17)28-12-11-20(14-23(28)29)30-15-16-5-7-18(25)8-6-16/h5-14,17H,2-4,15H2,1H3 FRJYKDRDGZNEJI-UHFFFAOYSA-N 50161846 CHEMBL3793700 Melanin-concentrating hormone receptor 1 Rattus 210 ChEMBL 10.1016/j.bmc.2016.04.011 10.7270/Q2862JB1 27112449 Igawa, H; Takahashi, M; Shirasaki, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Okuda, S; Kawata, Y; Noguchi, T; Yamamoto, S; Fujioka, Y; Kundu, M; Khamrai, U; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161846 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161846&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 89691193 341096919 CHEMBL3793700 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490483 Cn1c(nc2ccc(cc12)-n1ccc(OCc2ccc(F)cc2)cc1=O)C1CC1 InChI=1S/C23H20FN3O2/c1-26-21-12-18(8-9-20(21)25-23(26)16-4-5-16)27-11-10-19(13-22(27)28)29-14-15-2-6-17(24)7-3-15/h2-3,6-13,16H,4-5,14H2,1H3 PCKRKAGRGQILDT-UHFFFAOYSA-N 50163466 CHEMBL3793767 Melanin-concentrating hormone receptor 1 Rattus 28 ChEMBL 10.1016/j.bmc.2016.04.011 10.7270/Q2862JB1 27112449 Igawa, H; Takahashi, M; Shirasaki, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Okuda, S; Kawata, Y; Noguchi, T; Yamamoto, S; Fujioka, Y; Kundu, M; Khamrai, U; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163466 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163466&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 71660915 104049466 CHEMBL3793767 ZINC28114116 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490484 CCCc1nc2ccc(cc2n1C)-n1ccc(OCc2ccc(F)cc2)cc1=O InChI=1S/C23H22FN3O2/c1-3-4-22-25-20-10-9-18(13-21(20)26(22)2)27-12-11-19(14-23(27)28)29-15-16-5-7-17(24)8-6-16/h5-14H,3-4,15H2,1-2H3 FJNVAWAOWNBJEP-UHFFFAOYSA-N 50163465 CHEMBL3793182 Melanin-concentrating hormone receptor 1 Rattus 39 ChEMBL 10.1016/j.bmc.2016.04.011 10.7270/Q2862JB1 27112449 Igawa, H; Takahashi, M; Shirasaki, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Okuda, S; Kawata, Y; Noguchi, T; Yamamoto, S; Fujioka, Y; Kundu, M; Khamrai, U; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163465&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 89691535 104049465 CHEMBL3793182 ZINC28111842 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490485 CCc1nc2ccc(cc2n1C)-n1ccc(OCc2ccc(F)cc2)cc1=O InChI=1S/C22H20FN3O2/c1-3-21-24-19-9-8-17(12-20(19)25(21)2)26-11-10-18(13-22(26)27)28-14-15-4-6-16(23)7-5-15/h4-13H,3,14H2,1-2H3 UDLQRAVGQUJISV-UHFFFAOYSA-N 50163471 CHEMBL3792485 Melanin-concentrating hormone receptor 1 Rattus 38 ChEMBL 10.1016/j.bmc.2016.04.011 10.7270/Q2862JB1 27112449 Igawa, H; Takahashi, M; Shirasaki, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Okuda, S; Kawata, Y; Noguchi, T; Yamamoto, S; Fujioka, Y; Kundu, M; Khamrai, U; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163471&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 71660914 104049471 CHEMBL3792485 ZINC28113902 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490486 Cn1c(nc2ccc(cc12)-n1ccc(OCc2ccccc2)cc1=O)C1CC1 InChI=1S/C23H21N3O2/c1-25-21-13-18(9-10-20(21)24-23(25)17-7-8-17)26-12-11-19(14-22(26)27)28-15-16-5-3-2-4-6-16/h2-6,9-14,17H,7-8,15H2,1H3 GMKUXLCFJXBODY-UHFFFAOYSA-N 50163437 CHEMBL3793953 Melanin-concentrating hormone receptor 1 Rattus 43 ChEMBL 10.1016/j.bmc.2016.04.011 10.7270/Q2862JB1 27112449 Igawa, H; Takahashi, M; Shirasaki, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Okuda, S; Kawata, Y; Noguchi, T; Yamamoto, S; Fujioka, Y; Kundu, M; Khamrai, U; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163437 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163437&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 89691032 104049437 CHEMBL3793953 ZINC34633681 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490487 CCCn1c(nc2ccc(cc12)-n1ccc(OCc2ccc(Cl)cc2)cc1=O)C1CC1 InChI=1S/C25H24ClN3O2/c1-2-12-29-23-14-20(9-10-22(23)27-25(29)18-5-6-18)28-13-11-21(15-24(28)30)31-16-17-3-7-19(26)8-4-17/h3-4,7-11,13-15,18H,2,5-6,12,16H2,1H3 INYBZJXEQNJROZ-UHFFFAOYSA-N 50163444 CHEMBL3794238 Melanin-concentrating hormone receptor 1 Rattus 110 ChEMBL 10.1016/j.bmc.2016.04.011 10.7270/Q2862JB1 27112449 Igawa, H; Takahashi, M; Shirasaki, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Okuda, S; Kawata, Y; Noguchi, T; Yamamoto, S; Fujioka, Y; Kundu, M; Khamrai, U; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163444 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163444&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 89691057 104049444 CHEMBL3794238 ZINC36351348 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490488 CCn1c(nc2ccc(cc12)-n1ccc(OCc2ccc(Cl)cc2)cc1=O)C1CC1 InChI=1S/C24H22ClN3O2/c1-2-27-22-13-19(9-10-21(22)26-24(27)17-5-6-17)28-12-11-20(14-23(28)29)30-15-16-3-7-18(25)8-4-16/h3-4,7-14,17H,2,5-6,15H2,1H3 HGMHZLGJIPRCMS-UHFFFAOYSA-N 50161850 CHEMBL3793625 Melanin-concentrating hormone receptor 1 Rattus 34 ChEMBL 10.1016/j.bmc.2016.04.011 10.7270/Q2862JB1 27112449 Igawa, H; Takahashi, M; Shirasaki, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Okuda, S; Kawata, Y; Noguchi, T; Yamamoto, S; Fujioka, Y; Kundu, M; Khamrai, U; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161850 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161850&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 89691247 104048137 CHEMBL3793625 ZINC13609296 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490489 Cn1c(CC(C)(C)C)nc2ccc(cc12)-n1ccc(OCc2ccc(F)cc2)cc1=O InChI=1S/C25H26FN3O2/c1-25(2,3)15-23-27-21-10-9-19(13-22(21)28(23)4)29-12-11-20(14-24(29)30)31-16-17-5-7-18(26)8-6-17/h5-14H,15-16H2,1-4H3 WZOCZVZTFHKQAO-UHFFFAOYSA-N 50161849 CHEMBL3792417 Melanin-concentrating hormone receptor 1 Rattus >1000 ChEMBL 10.1016/j.bmc.2016.04.011 10.7270/Q2862JB1 27112449 Igawa, H; Takahashi, M; Shirasaki, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Okuda, S; Kawata, Y; Noguchi, T; Yamamoto, S; Fujioka, Y; Kundu, M; Khamrai, U; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161849 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161849&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 89691349 341096921 CHEMBL3792417 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490498 Cc1nc2ccc(cc2n1C)-n1ccc(OCc2ccc(F)cc2)cc1=O InChI=1S/C21H18FN3O2/c1-14-23-19-8-7-17(11-20(19)24(14)2)25-10-9-18(12-21(25)26)27-13-15-3-5-16(22)6-4-15/h3-12H,13H2,1-2H3 WSKXMIQVCMWHGL-UHFFFAOYSA-N 50163486 CHEMBL3793118 Melanin-concentrating hormone receptor 1 Rattus 65 ChEMBL 10.1016/j.bmc.2016.04.011 10.7270/Q2862JB1 27112449 Igawa, H; Takahashi, M; Shirasaki, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Okuda, S; Kawata, Y; Noguchi, T; Yamamoto, S; Fujioka, Y; Kundu, M; Khamrai, U; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163486 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163486&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 71660917 104049486 CHEMBL3793118 ZINC28115936 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490500 Cn1c(nc2ccc(cc12)-n1ccc(OCc2ccc(Cl)cc2)cc1=O)C1CC1 InChI=1S/C23H20ClN3O2/c1-26-21-12-18(8-9-20(21)25-23(26)16-4-5-16)27-11-10-19(13-22(27)28)29-14-15-2-6-17(24)7-3-15/h2-3,6-13,16H,4-5,14H2,1H3 KNHLUQAURZOTFL-UHFFFAOYSA-N 50163490 CHEMBL3793944 Melanin-concentrating hormone receptor 1 Rattus 21 ChEMBL 10.1016/j.bmc.2016.04.011 10.7270/Q2862JB1 27112449 Igawa, H; Takahashi, M; Shirasaki, M; Kakegawa, K; Kina, A; Ikoma, M; Aida, J; Yasuma, T; Okuda, S; Kawata, Y; Noguchi, T; Yamamoto, S; Fujioka, Y; Kundu, M; Khamrai, U; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163490 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163490&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 89690864 104049490 CHEMBL3793944 ZINC28113372 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490504 Cc1n(C)nc2ccc(cc12)-n1ccc(OCc2ccc(Cl)cc2)cc1=O InChI=1S/C21H18ClN3O2/c1-14-19-11-17(7-8-20(19)23-24(14)2)25-10-9-18(12-21(25)26)27-13-15-3-5-16(22)6-4-15/h3-12H,13H2,1-2H3 ILAODGHSGTUINL-UHFFFAOYSA-N 50163497 CHEMBL3578242 Melanin-concentrating hormone receptor 1 Rattus 36 ChEMBL 10.1016/j.bmc.2016.04.013 10.7270/Q2SX6G4X 27117261 Igawa, H; Takahashi, M; Ikoma, M; Kaku, H; Kakegawa, K; Kina, A; Aida, J; Okuda, S; Kawata, Y; Noguchi, T; Hotta, N; Yamamoto, S; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163497 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163497&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 86582974 104049497 CHEMBL3578242 ZINC28106148 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490505 Cc1n(C)nc2ccc(cc12)-n1ccc(OCc2ccc(s2)C(F)(F)F)cc1=O InChI=1S/C20H16F3N3O2S/c1-12-16-9-13(3-5-17(16)24-25(12)2)26-8-7-14(10-19(26)27)28-11-15-4-6-18(29-15)20(21,22)23/h3-10H,11H2,1-2H3 XWFNNLQMTXNZJH-UHFFFAOYSA-N 50163499 CHEMBL3792893 Melanin-concentrating hormone receptor 1 Rattus 90 ChEMBL 10.1016/j.bmc.2016.04.013 10.7270/Q2SX6G4X 27117261 Igawa, H; Takahashi, M; Ikoma, M; Kaku, H; Kakegawa, K; Kina, A; Aida, J; Okuda, S; Kawata, Y; Noguchi, T; Hotta, N; Yamamoto, S; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163499 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163499&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 117798692 341097209 CHEMBL3792893 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490506 Cc1n(C)nc2ccc(cc12)-n1ccc(OCc2cc(cs2)C(F)(F)F)cc1=O InChI=1S/C20H16F3N3O2S/c1-12-17-8-14(3-4-18(17)24-25(12)2)26-6-5-15(9-19(26)27)28-10-16-7-13(11-29-16)20(21,22)23/h3-9,11H,10H2,1-2H3 VNLUVGGPOWIHCQ-UHFFFAOYSA-N 50163500 CHEMBL3793841 Melanin-concentrating hormone receptor 1 Rattus 38 ChEMBL 10.1016/j.bmc.2016.04.013 10.7270/Q2SX6G4X 27117261 Igawa, H; Takahashi, M; Ikoma, M; Kaku, H; Kakegawa, K; Kina, A; Aida, J; Okuda, S; Kawata, Y; Noguchi, T; Hotta, N; Yamamoto, S; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163500 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163500&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 117816748 341097210 CHEMBL3793841 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490507 Cc1n(C)nc2ccc(cc12)-n1ccc(OCc2csc(c2)C(F)(F)F)cc1=O InChI=1S/C20H16F3N3O2S/c1-12-16-8-14(3-4-17(16)24-25(12)2)26-6-5-15(9-19(26)27)28-10-13-7-18(29-11-13)20(21,22)23/h3-9,11H,10H2,1-2H3 HCPZBYNMKVQXBT-UHFFFAOYSA-N 50163501 CHEMBL3793001 Melanin-concentrating hormone receptor 1 Rattus 70 ChEMBL 10.1016/j.bmc.2016.04.013 10.7270/Q2SX6G4X 27117261 Igawa, H; Takahashi, M; Ikoma, M; Kaku, H; Kakegawa, K; Kina, A; Aida, J; Okuda, S; Kawata, Y; Noguchi, T; Hotta, N; Yamamoto, S; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163501 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163501&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 117798671 341097211 CHEMBL3793001 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490508 Cc1n(C)nc2ccc(cc12)-n1ccc(OCc2nc(cs2)C(F)(F)F)cc1=O InChI=1S/C19H15F3N4O2S/c1-11-14-7-12(3-4-15(14)24-25(11)2)26-6-5-13(8-18(26)27)28-9-17-23-16(10-29-17)19(20,21)22/h3-8,10H,9H2,1-2H3 XMNXODJNMMIWIF-UHFFFAOYSA-N 50163502 CHEMBL3793312 Melanin-concentrating hormone receptor 1 Rattus 76 ChEMBL 10.1016/j.bmc.2016.04.013 10.7270/Q2SX6G4X 27117261 Igawa, H; Takahashi, M; Ikoma, M; Kaku, H; Kakegawa, K; Kina, A; Aida, J; Okuda, S; Kawata, Y; Noguchi, T; Hotta, N; Yamamoto, S; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163502 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163502&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 117798780 341097212 CHEMBL3793312 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490509 Cc1n(C)nc2ccc(cc12)-n1ccc(OCc2csc(n2)C(F)(F)F)cc1=O InChI=1S/C19H15F3N4O2S/c1-11-15-7-13(3-4-16(15)24-25(11)2)26-6-5-14(8-17(26)27)28-9-12-10-29-18(23-12)19(20,21)22/h3-8,10H,9H2,1-2H3 WNMFHDWYPNFDBY-UHFFFAOYSA-N 50163503 CHEMBL3793142 Melanin-concentrating hormone receptor 1 Rattus 130 ChEMBL 10.1016/j.bmc.2016.04.013 10.7270/Q2SX6G4X 27117261 Igawa, H; Takahashi, M; Ikoma, M; Kaku, H; Kakegawa, K; Kina, A; Aida, J; Okuda, S; Kawata, Y; Noguchi, T; Hotta, N; Yamamoto, S; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163503 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163503&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 117798680 341097213 CHEMBL3793142 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490510 Cc1n(C)nc2ccc(cc12)-n1ccc(OCc2ccc(F)cc2)cc1=O InChI=1S/C21H18FN3O2/c1-14-19-11-17(7-8-20(19)23-24(14)2)25-10-9-18(12-21(25)26)27-13-15-3-5-16(22)6-4-15/h3-12H,13H2,1-2H3 RSGOXAZXFIAPQW-UHFFFAOYSA-N 50163504 CHEMBL3792764 Melanin-concentrating hormone receptor 1 Rattus 76 ChEMBL 10.1016/j.bmc.2016.04.013 10.7270/Q2SX6G4X 27117261 Igawa, H; Takahashi, M; Ikoma, M; Kaku, H; Kakegawa, K; Kina, A; Aida, J; Okuda, S; Kawata, Y; Noguchi, T; Hotta, N; Yamamoto, S; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163504 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163504&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 117816753 341097214 CHEMBL3792764 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490511 CCn1nc2ccc(cc2c1C)-n1ccc(OCc2ccc(Cl)cc2)cc1=O InChI=1S/C22H20ClN3O2/c1-3-26-15(2)20-12-18(8-9-21(20)24-26)25-11-10-19(13-22(25)27)28-14-16-4-6-17(23)7-5-16/h4-13H,3,14H2,1-2H3 VXRBUXUFJAMXRA-UHFFFAOYSA-N 50163505 CHEMBL3793016 Melanin-concentrating hormone receptor 1 Rattus 65 ChEMBL 10.1016/j.bmc.2016.04.013 10.7270/Q2SX6G4X 27117261 Igawa, H; Takahashi, M; Ikoma, M; Kaku, H; Kakegawa, K; Kina, A; Aida, J; Okuda, S; Kawata, Y; Noguchi, T; Hotta, N; Yamamoto, S; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163505 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163505&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 117798675 341097215 CHEMBL3793016 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490512 CCCn1nc2ccc(cc2c1C)-n1ccc(OCc2ccc(Cl)cc2)cc1=O InChI=1S/C23H22ClN3O2/c1-3-11-27-16(2)21-13-19(8-9-22(21)25-27)26-12-10-20(14-23(26)28)29-15-17-4-6-18(24)7-5-17/h4-10,12-14H,3,11,15H2,1-2H3 STNZKQGKFPXQMF-UHFFFAOYSA-N 50163506 CHEMBL3794208 Melanin-concentrating hormone receptor 1 Rattus 130 ChEMBL 10.1016/j.bmc.2016.04.013 10.7270/Q2SX6G4X 27117261 Igawa, H; Takahashi, M; Ikoma, M; Kaku, H; Kakegawa, K; Kina, A; Aida, J; Okuda, S; Kawata, Y; Noguchi, T; Hotta, N; Yamamoto, S; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163506 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163506&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 117798688 341097216 CHEMBL3794208 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490513 Cc1n(nc2ccc(cc12)-n1ccc(OCc2ccc(Cl)cc2)cc1=O)C1CC1 InChI=1S/C23H20ClN3O2/c1-15-21-12-19(8-9-22(21)25-27(15)18-6-7-18)26-11-10-20(13-23(26)28)29-14-16-2-4-17(24)5-3-16/h2-5,8-13,18H,6-7,14H2,1H3 NLQGIADBJJOEFQ-UHFFFAOYSA-N 50163507 CHEMBL3794256 Melanin-concentrating hormone receptor 1 Rattus 23 ChEMBL 10.1016/j.bmc.2016.04.013 10.7270/Q2SX6G4X 27117261 Igawa, H; Takahashi, M; Ikoma, M; Kaku, H; Kakegawa, K; Kina, A; Aida, J; Okuda, S; Kawata, Y; Noguchi, T; Hotta, N; Yamamoto, S; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163507 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163507&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 117798744 341097217 CHEMBL3794256 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490514 Cc1n(nc2ccc(cc12)-n1ccc(OCc2ccc(F)cc2)cc1=O)C1CC1 InChI=1S/C23H20FN3O2/c1-15-21-12-19(8-9-22(21)25-27(15)18-6-7-18)26-11-10-20(13-23(26)28)29-14-16-2-4-17(24)5-3-16/h2-5,8-13,18H,6-7,14H2,1H3 WFEMDTGQEARDBR-UHFFFAOYSA-N 50163508 CHEMBL3578243 Melanin-concentrating hormone receptor 1 Rattus 35 ChEMBL 10.1016/j.bmc.2016.04.013 10.7270/Q2SX6G4X 27117261 Igawa, H; Takahashi, M; Ikoma, M; Kaku, H; Kakegawa, K; Kina, A; Aida, J; Okuda, S; Kawata, Y; Noguchi, T; Hotta, N; Yamamoto, S; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163508 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163508&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 117816804 341097218 CHEMBL3578243 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50490515 Cc1n(nc2ccc(cc12)-n1ccc(OCc2csc(c2)C(F)(F)F)cc1=O)C1CC1 InChI=1S/C22H18F3N3O2S/c1-13-18-9-16(4-5-19(18)26-28(13)15-2-3-15)27-7-6-17(10-21(27)29)30-11-14-8-20(31-12-14)22(23,24)25/h4-10,12,15H,2-3,11H2,1H3 FAALBEAEXAFDGY-UHFFFAOYSA-N 50163509 CHEMBL3578244 Melanin-concentrating hormone receptor 1 Rattus 26 ChEMBL 10.1016/j.bmc.2016.04.013 10.7270/Q2SX6G4X 27117261 Igawa, H; Takahashi, M; Ikoma, M; Kaku, H; Kakegawa, K; Kina, A; Aida, J; Okuda, S; Kawata, Y; Noguchi, T; Hotta, N; Yamamoto, S; Nakayama, M; Nagisa, Y; Kasai, S; Maekawa, T Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50163509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50163509&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 90469437 341097219 CHEMBL3578244 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50661603 CN1CC(C1)c1c[nH]c2cc(ccc12)-n1ccc(OCc2ccccc2)cc1=O InChI=1S/C24H23N3O2/c1-26-14-18(15-26)22-13-25-23-11-19(7-8-21(22)23)27-10-9-20(12-24(27)28)29-16-17-5-3-2-4-6-17/h2-13,18,25H,14-16H2,1H3 VENQEUPIUTUQBC-UHFFFAOYSA-N 50353448 CHEMBL1830042 Melanin-concentrating hormone receptor 1 Rattus 11 ChEMBL 10.1016/j.bmcl.2011.07.020 10.7270/Q2DJ5G0J 21802292 Lu, K; Jiang, Y; Chen, B; Eldemenky, EM; Ma, G; Packiarajan, M; Chandrasena, G; White, AD; Jones, KA; Li, B; Hong, SP Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50353448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50353448&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 46869326 136360134 CHEMBL1830042 ZINC43208507 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50661604 CN1CC(C1)c1c[nH]c2cc(ccc12)-n1ccc(OCc2ccccc2F)cc1=O InChI=1S/C24H22FN3O2/c1-27-13-17(14-27)21-12-26-23-10-18(6-7-20(21)23)28-9-8-19(11-24(28)29)30-15-16-4-2-3-5-22(16)25/h2-12,17,26H,13-15H2,1H3 KMMWYEGCINPOGT-UHFFFAOYSA-N 50353449 CHEMBL1830043 Melanin-concentrating hormone receptor 1 Rattus 6.7 ChEMBL 10.1016/j.bmcl.2011.07.020 10.7270/Q2DJ5G0J 21802292 Lu, K; Jiang, Y; Chen, B; Eldemenky, EM; Ma, G; Packiarajan, M; Chandrasena, G; White, AD; Jones, KA; Li, B; Hong, SP Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50353449 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50353449&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 56666883 136360135 CHEMBL1830043 ZINC72116464 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50661605 CN1CC(C1)c1c[nH]c2cc(ccc12)-n1ccc(cc1=O)-c1ccc(Cl)cc1 InChI=1S/C23H20ClN3O/c1-26-13-17(14-26)21-12-25-22-11-19(6-7-20(21)22)27-9-8-16(10-23(27)28)15-2-4-18(24)5-3-15/h2-12,17,25H,13-14H2,1H3 BXLCZBUXHOIRET-UHFFFAOYSA-N 50353450 CHEMBL1830044 Melanin-concentrating hormone receptor 1 Rattus 7.8 ChEMBL 10.1016/j.bmcl.2011.07.020 10.7270/Q2DJ5G0J 21802292 Lu, K; Jiang, Y; Chen, B; Eldemenky, EM; Ma, G; Packiarajan, M; Chandrasena, G; White, AD; Jones, KA; Li, B; Hong, SP Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50353450 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50353450&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44224161 136360136 CHEMBL1830044 ZINC43208506 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50661606 CN1CC(C1)c1cn(C)c2cc(ccc12)-n1ccc(OCc2ccccc2)cc1=O InChI=1S/C25H25N3O2/c1-26-14-19(15-26)23-16-27(2)24-12-20(8-9-22(23)24)28-11-10-21(13-25(28)29)30-17-18-6-4-3-5-7-18/h3-13,16,19H,14-15,17H2,1-2H3 ABNYRAHLXKZBKK-UHFFFAOYSA-N 50353451 CHEMBL1830045 Melanin-concentrating hormone receptor 1 Rattus 11 ChEMBL 10.1016/j.bmcl.2011.07.020 10.7270/Q2DJ5G0J 21802292 Lu, K; Jiang, Y; Chen, B; Eldemenky, EM; Ma, G; Packiarajan, M; Chandrasena, G; White, AD; Jones, KA; Li, B; Hong, SP Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50353451 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50353451&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 56680482 136360137 CHEMBL1830045 ZINC72116465 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50661607 COCCN1CC(C1)c1c[nH]c2cc(ccc12)-n1ccc(OCc2ccccc2)cc1=O InChI=1S/C26H27N3O3/c1-31-12-11-28-16-20(17-28)24-15-27-25-13-21(7-8-23(24)25)29-10-9-22(14-26(29)30)32-18-19-5-3-2-4-6-19/h2-10,13-15,20,27H,11-12,16-18H2,1H3 JXCRAGNWKFXKSX-UHFFFAOYSA-N 50353452 CHEMBL1830046 Melanin-concentrating hormone receptor 1 Rattus 5.2 ChEMBL 10.1016/j.bmcl.2011.07.020 10.7270/Q2DJ5G0J 21802292 Lu, K; Jiang, Y; Chen, B; Eldemenky, EM; Ma, G; Packiarajan, M; Chandrasena, G; White, AD; Jones, KA; Li, B; Hong, SP Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50353452 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50353452&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 56660001 136360138 CHEMBL1830046 ZINC72114707 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50661608 FCCN1CC(C1)c1c[nH]c2cc(ccc12)-n1ccc(OCc2ccccc2)cc1=O InChI=1S/C25H24FN3O2/c26-9-11-28-15-19(16-28)23-14-27-24-12-20(6-7-22(23)24)29-10-8-21(13-25(29)30)31-17-18-4-2-1-3-5-18/h1-8,10,12-14,19,27H,9,11,15-17H2 HSSYJLUDDDEVOO-UHFFFAOYSA-N 50353453 CHEMBL1830047 Melanin-concentrating hormone receptor 1 Rattus 4.3 ChEMBL 10.1016/j.bmcl.2011.07.020 10.7270/Q2DJ5G0J 21802292 Lu, K; Jiang, Y; Chen, B; Eldemenky, EM; Ma, G; Packiarajan, M; Chandrasena, G; White, AD; Jones, KA; Li, B; Hong, SP Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50353453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50353453&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 56673836 136360139 CHEMBL1830047 ZINC72118268 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50661609 Cn1cc(C2CN(CCF)C2)c2ccc(cc12)-n1ccc(cc1=O)-c1ccc(F)cc1 InChI=1S/C25H23F2N3O/c1-28-16-23(19-14-29(15-19)11-9-26)22-7-6-21(13-24(22)28)30-10-8-18(12-25(30)31)17-2-4-20(27)5-3-17/h2-8,10,12-13,16,19H,9,11,14-15H2,1H3 MOOWWSHIGGBBGB-UHFFFAOYSA-N 50353454 CHEMBL1830048 Melanin-concentrating hormone receptor 1 Rattus 9 ChEMBL 10.1016/j.bmcl.2011.07.020 10.7270/Q2DJ5G0J 21802292 Lu, K; Jiang, Y; Chen, B; Eldemenky, EM; Ma, G; Packiarajan, M; Chandrasena, G; White, AD; Jones, KA; Li, B; Hong, SP Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50353454 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50353454&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44480332 136360140 CHEMBL1830048 ZINC72116177 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50661610 O=c1cc(OCc2ccccc2)ccn1-c1ccc2N(CCc2c1)C1CNC1 InChI=1S/C23H23N3O2/c27-23-13-21(28-16-17-4-2-1-3-5-17)9-11-26(23)19-6-7-22-18(12-19)8-10-25(22)20-14-24-15-20/h1-7,9,11-13,20,24H,8,10,14-16H2 PTZDRLXZJMSQRF-UHFFFAOYSA-N 50353455 CHEMBL1830049 Melanin-concentrating hormone receptor 1 Rattus 2.4 ChEMBL 10.1016/j.bmcl.2011.07.020 10.7270/Q2DJ5G0J 21802292 Lu, K; Jiang, Y; Chen, B; Eldemenky, EM; Ma, G; Packiarajan, M; Chandrasena, G; White, AD; Jones, KA; Li, B; Hong, SP Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50353455 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50353455&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44481640 136360141 CHEMBL1830049 ZINC72116760 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50661611 CN1CC(C1)N1CCc2cc(ccc12)-n1ccc(OCc2ccccc2)cc1=O InChI=1S/C24H25N3O2/c1-25-15-21(16-25)26-11-9-19-13-20(7-8-23(19)26)27-12-10-22(14-24(27)28)29-17-18-5-3-2-4-6-18/h2-8,10,12-14,21H,9,11,15-17H2,1H3 MSFJSSSKPPVGMF-UHFFFAOYSA-N 50353456 CHEMBL1830050 Melanin-concentrating hormone receptor 1 Rattus 2.5 ChEMBL 10.1016/j.bmcl.2011.07.020 10.7270/Q2DJ5G0J 21802292 Lu, K; Jiang, Y; Chen, B; Eldemenky, EM; Ma, G; Packiarajan, M; Chandrasena, G; White, AD; Jones, KA; Li, B; Hong, SP Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50353456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50353456&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44481905 136360142 CHEMBL1830050 ZINC72114389 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50661612 FCCN1CC(C1)N1CCc2cc(ccc12)-n1ccc(OCc2ccccc2)cc1=O InChI=1S/C25H26FN3O2/c26-10-13-27-16-22(17-27)28-11-8-20-14-21(6-7-24(20)28)29-12-9-23(15-25(29)30)31-18-19-4-2-1-3-5-19/h1-7,9,12,14-15,22H,8,10-11,13,16-18H2 PDSSICZHZFNOOI-UHFFFAOYSA-N 50353457 CHEMBL1830051 Melanin-concentrating hormone receptor 1 Rattus 4.9 ChEMBL 10.1016/j.bmcl.2011.07.020 10.7270/Q2DJ5G0J 21802292 Lu, K; Jiang, Y; Chen, B; Eldemenky, EM; Ma, G; Packiarajan, M; Chandrasena, G; White, AD; Jones, KA; Li, B; Hong, SP Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50353457 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50353457&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44481638 136360143 CHEMBL1830051 ZINC68247545 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50661613 CN1CC(C1)N1CCc2cc(ccc12)-n1ccc(cc1=O)-c1ccc(Cl)cc1 InChI=1S/C23H22ClN3O/c1-25-14-21(15-25)26-10-9-18-12-20(6-7-22(18)26)27-11-8-17(13-23(27)28)16-2-4-19(24)5-3-16/h2-8,11-13,21H,9-10,14-15H2,1H3 MFWGGNQVVILSFU-UHFFFAOYSA-N 50353458 CHEMBL1830052 Melanin-concentrating hormone receptor 1 Rattus 4.9 ChEMBL 10.1016/j.bmcl.2011.07.020 10.7270/Q2DJ5G0J 21802292 Lu, K; Jiang, Y; Chen, B; Eldemenky, EM; Ma, G; Packiarajan, M; Chandrasena, G; White, AD; Jones, KA; Li, B; Hong, SP Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50353458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50353458&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44462720 136360144 CHEMBL1830052 ZINC68197258 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50661614 FCCN1CC(C1)N1CCc2cc(ccc12)-n1ccc(cc1=O)-c1ccc(Cl)cc1 InChI=1S/C24H23ClFN3O/c25-20-3-1-17(2-4-20)18-7-11-29(24(30)14-18)21-5-6-23-19(13-21)8-10-28(23)22-15-27(16-22)12-9-26/h1-7,11,13-14,22H,8-10,12,15-16H2 KXPUATVYWXKDJH-UHFFFAOYSA-N 50353459 CHEMBL1830053 Melanin-concentrating hormone receptor 1 Rattus 6.5 ChEMBL 10.1016/j.bmcl.2011.07.020 10.7270/Q2DJ5G0J 21802292 Lu, K; Jiang, Y; Chen, B; Eldemenky, EM; Ma, G; Packiarajan, M; Chandrasena, G; White, AD; Jones, KA; Li, B; Hong, SP Lundbeck Research USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50353459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50353459&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 44481364 136360145 CHEMBL1830053 ZINC68197260 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656286 CN(C)CC1CCc2cc(NC(=O)c3ccc(cc3)-c3ccccc3)ccc2C1 InChI=1S/C26H28N2O/c1-28(2)18-19-8-9-24-17-25(15-14-23(24)16-19)27-26(29)22-12-10-21(11-13-22)20-6-4-3-5-7-20/h3-7,10-15,17,19H,8-9,16,18H2,1-2H3,(H,27,29) SHTXMWXRCCYBMW-UHFFFAOYSA-N 50351291 CHEMBL1818777 Melanin-concentrating hormone receptor 1 Rattus 95 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351291 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351291&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 21939767 136357977 CHEMBL1818777 ZINC72113404 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656287 CN(C)CC1CCc2cc(NC(=O)c3ccc(cc3)-c3ccccc3Cl)ccc2C1 InChI=1S/C26H27ClN2O/c1-29(2)17-18-7-8-22-16-23(14-13-21(22)15-18)28-26(30)20-11-9-19(10-12-20)24-5-3-4-6-25(24)27/h3-6,9-14,16,18H,7-8,15,17H2,1-2H3,(H,28,30) KTDMCLCTLWFDGI-UHFFFAOYSA-N 50351295 CHEMBL1818781 Melanin-concentrating hormone receptor 1 Rattus 23 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351295 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351295&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 21062990 136357981 CHEMBL1818781 ZINC72113567 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656288 CN(C)CC1CCc2cc(NC(=O)c3ccc(cc3)-c3cccc(Cl)c3)ccc2C1 InChI=1S/C26H27ClN2O/c1-29(2)17-18-6-7-23-16-25(13-12-22(23)14-18)28-26(30)20-10-8-19(9-11-20)21-4-3-5-24(27)15-21/h3-5,8-13,15-16,18H,6-7,14,17H2,1-2H3,(H,28,30) QXQYXUMJJNTKCX-UHFFFAOYSA-N 50351296 CHEMBL1818782 Melanin-concentrating hormone receptor 1 Rattus 220 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351296&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 21062991 136357982 CHEMBL1818782 ZINC72114174 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656289 CN(C)CC1CCc2cc(NC(=O)c3ccc(cc3)-c3ccc(F)cc3)ccc2C1 InChI=1S/C26H27FN2O/c1-29(2)17-18-3-4-23-16-25(14-11-22(23)15-18)28-26(30)21-7-5-19(6-8-21)20-9-12-24(27)13-10-20/h5-14,16,18H,3-4,15,17H2,1-2H3,(H,28,30) GXAQELJVODWLDD-UHFFFAOYSA-N 50150715 4''-Fluoro-biphenyl-4-carboxylic acid (6-dimethylaminomethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-amide::4'-fluoro-biphenyl-4-carboxylic acid (6-dimethylaminomethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-amide::CHEMBL178707::N-(6-((dimethylamino)methyl)-5,6,7,8-tetrahydronaphthalen-2-yl)-4'-fluorobiphenyl-4-carboxamide::T-226296 Melanin-concentrating hormone receptor 1 Rattus 24 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150715 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150715&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 9865843 104039074 CHEMBL178707 1314 ZINC03972273 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656290 CN(C)CC1CCc2cc(NC(=O)c3ccc(cc3)-c3ccc(C)cc3)ccc2C1 InChI=1S/C27H30N2O/c1-19-4-7-21(8-5-19)22-10-12-23(13-11-22)27(30)28-26-15-14-24-16-20(18-29(2)3)6-9-25(24)17-26/h4-5,7-8,10-15,17,20H,6,9,16,18H2,1-3H3,(H,28,30) LZYYQXOPZXIZAG-UHFFFAOYSA-N 50351298 CHEMBL1818784 Melanin-concentrating hormone receptor 1 Rattus 12 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351298 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351298&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 23593474 136357984 CHEMBL1818784 ZINC72113059 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656291 CCc1ccc(cc1)-c1ccc(cc1)C(=O)Nc1ccc2CC(CN(C)C)CCc2c1 InChI=1S/C28H32N2O/c1-4-20-5-8-22(9-6-20)23-11-13-24(14-12-23)28(31)29-27-16-15-25-17-21(19-30(2)3)7-10-26(25)18-27/h5-6,8-9,11-16,18,21H,4,7,10,17,19H2,1-3H3,(H,29,31) IOHAOIFSDVOIOB-UHFFFAOYSA-N 50351299 CHEMBL1818785 Melanin-concentrating hormone receptor 1 Rattus 21 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351299&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 23593468 136357985 CHEMBL1818785 ZINC72113061 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656292 CCCc1ccc(cc1)-c1ccc(cc1)C(=O)Nc1ccc2CC(CN(C)C)CCc2c1 InChI=1S/C29H34N2O/c1-4-5-21-6-9-23(10-7-21)24-12-14-25(15-13-24)29(32)30-28-17-16-26-18-22(20-31(2)3)8-11-27(26)19-28/h6-7,9-10,12-17,19,22H,4-5,8,11,18,20H2,1-3H3,(H,30,32) GLGPWCKZXKIUPZ-UHFFFAOYSA-N 50351325 CHEMBL1818786 Melanin-concentrating hormone receptor 1 Rattus 210 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351325&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 23593472 136358011 CHEMBL1818786 ZINC72113157 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656293 COc1ccc(cc1)-c1ccc(cc1)C(=O)Nc1ccc2CC(CN(C)C)CCc2c1 InChI=1S/C27H30N2O2/c1-29(2)18-19-4-5-24-17-25(13-10-23(24)16-19)28-27(30)22-8-6-20(7-9-22)21-11-14-26(31-3)15-12-21/h6-15,17,19H,4-5,16,18H2,1-3H3,(H,28,30) ZLENJXHJTDYRCQ-UHFFFAOYSA-N 50351301 CHEMBL1818788 Melanin-concentrating hormone receptor 1 Rattus 22 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351301 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351301&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 9844702 136357987 CHEMBL1818788 ZINC03935868 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656294 CN(C)CC1CCc2cc(NCc3ccc(cc3)-c3ccccc3)ccc2C1 InChI=1S/C26H30N2/c1-28(2)19-21-10-13-25-17-26(15-14-24(25)16-21)27-18-20-8-11-23(12-9-20)22-6-4-3-5-7-22/h3-9,11-12,14-15,17,21,27H,10,13,16,18-19H2,1-2H3 OYEJDXFRODAUIU-UHFFFAOYSA-N 50351305 CHEMBL1818792 Melanin-concentrating hormone receptor 1 Rattus >1000 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351305 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351305&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 18361509 136357991 CHEMBL1818792 ZINC72114395 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656295 CN(C)CC1CCc2cc(NS(=O)(=O)c3ccc(cc3)-c3ccccc3)ccc2C1 InChI=1S/C25H28N2O2S/c1-27(2)18-19-8-9-23-17-24(13-10-22(23)16-19)26-30(28,29)25-14-11-21(12-15-25)20-6-4-3-5-7-20/h3-7,10-15,17,19,26H,8-9,16,18H2,1-2H3 BMCLCCGIUCWIFZ-UHFFFAOYSA-N 50351306 CHEMBL1818793 Melanin-concentrating hormone receptor 1 Rattus >1000 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351306 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351306&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 21063022 136357992 CHEMBL1818793 ZINC72114397 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656296 CN(C)CC1CCc2cc(OC(=O)c3ccc(cc3)-c3ccccc3)ccc2C1 InChI=1S/C26H27NO2/c1-27(2)18-19-8-9-24-17-25(15-14-23(24)16-19)29-26(28)22-12-10-21(11-13-22)20-6-4-3-5-7-20/h3-7,10-15,17,19H,8-9,16,18H2,1-2H3 QNKNWRNJWYKTFB-UHFFFAOYSA-N 50351307 CHEMBL1818794 Melanin-concentrating hormone receptor 1 Rattus 280 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351307 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351307&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 21940052 136357993 CHEMBL1818794 ZINC72116342 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656297 CN(C)CC1=Cc2ccc(NC(=O)c3ccc(cc3)-c3ccc(Cl)cc3)cc2CC1 InChI=1S/C26H25ClN2O/c1-29(2)17-18-3-4-23-16-25(14-11-22(23)15-18)28-26(30)21-7-5-19(6-8-21)20-9-12-24(27)13-10-20/h5-16H,3-4,17H2,1-2H3,(H,28,30) QSERVTYJHOTWQD-UHFFFAOYSA-N 50351308 CHEMBL1818795 Melanin-concentrating hormone receptor 1 Rattus 2.7 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351308 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351308&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 22251624 136357994 CHEMBL1818795 ZINC72114813 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656298 CCN(CC)CC1=Cc2ccc(NC(=O)c3ccc(cc3)-c3ccc(Cl)cc3)cc2CC1 InChI=1S/C28H29ClN2O/c1-3-31(4-2)19-20-5-6-25-18-27(16-13-24(25)17-20)30-28(32)23-9-7-21(8-10-23)22-11-14-26(29)15-12-22/h7-18H,3-6,19H2,1-2H3,(H,30,32) RAERFBHNHNDJIP-UHFFFAOYSA-N 50351310 CHEMBL1818797 Melanin-concentrating hormone receptor 1 Rattus 14 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351310 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351310&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 56666754 136357996 CHEMBL1818797 ZINC72114112 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656299 CN(CCc1ccccc1)CC1=Cc2ccc(NC(=O)c3ccc(cc3)-c3ccc(Cl)cc3)cc2CC1 InChI=1S/C33H31ClN2O/c1-36(20-19-24-5-3-2-4-6-24)23-25-7-8-30-22-32(18-15-29(30)21-25)35-33(37)28-11-9-26(10-12-28)27-13-16-31(34)17-14-27/h2-6,9-18,21-22H,7-8,19-20,23H2,1H3,(H,35,37) JTXPQHDLXYZOSC-UHFFFAOYSA-N 50351311 CHEMBL1818798 Melanin-concentrating hormone receptor 1 Rattus 12 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351311 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351311&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 21062998 136357997 CHEMBL1818798 ZINC72114113 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656300 CN(CC1=Cc2ccc(NC(=O)c3ccc(cc3)-c3ccc(Cl)cc3)cc2CC1)c1ccccc1 InChI=1S/C31H27ClN2O/c1-34(30-5-3-2-4-6-30)21-22-7-8-27-20-29(18-15-26(27)19-22)33-31(35)25-11-9-23(10-12-25)24-13-16-28(32)17-14-24/h2-6,9-20H,7-8,21H2,1H3,(H,33,35) VIMHLPANVVNLHI-UHFFFAOYSA-N 50351326 CHEMBL1817681 Melanin-concentrating hormone receptor 1 Rattus 20 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351326 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351326&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 21062999 136358012 CHEMBL1817681 ZINC72116429 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656301 Clc1ccc(cc1)-c1ccc(cc1)C(=O)Nc1ccc2C=C(CN3CCOCC3)CCc2c1 InChI=1S/C28H27ClN2O2/c29-26-10-7-22(8-11-26)21-3-5-23(6-4-21)28(32)30-27-12-9-24-17-20(1-2-25(24)18-27)19-31-13-15-33-16-14-31/h3-12,17-18H,1-2,13-16,19H2,(H,30,32) YIIMZTFOEUJCDL-UHFFFAOYSA-N 50351327 CHEMBL1818799 Melanin-concentrating hormone receptor 1 Rattus 12 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351327 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351327&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 21939915 136358013 CHEMBL1818799 ZINC72116504 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656302 Clc1ccc(cc1)-c1ccc(cc1)C(=O)Nc1ccc2C=C(CN3CCCC3)CCc2c1 InChI=1S/C28H27ClN2O/c29-26-12-9-22(10-13-26)21-5-7-23(8-6-21)28(32)30-27-14-11-24-17-20(3-4-25(24)18-27)19-31-15-1-2-16-31/h5-14,17-18H,1-4,15-16,19H2,(H,30,32) XVBWALYMZPABOB-UHFFFAOYSA-N 50351312 CHEMBL1818800 Melanin-concentrating hormone receptor 1 Rattus 2.2 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351312 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351312&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 21939937 136357998 CHEMBL1818800 ZINC72114512 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656303 Clc1ccc(cc1)-c1ccc(cc1)C(=O)Nc1ccc2C=C(CN3CCCCC3)CCc2c1 InChI=1S/C29H29ClN2O/c30-27-13-10-23(11-14-27)22-6-8-24(9-7-22)29(33)31-28-15-12-25-18-21(4-5-26(25)19-28)20-32-16-2-1-3-17-32/h6-15,18-19H,1-5,16-17,20H2,(H,31,33) ORAHRHNNZIPNAN-UHFFFAOYSA-N 50351313 CHEMBL1818801 Melanin-concentrating hormone receptor 1 Rattus 2.5 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351313 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351313&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 21940083 136357999 CHEMBL1818801 ZINC72114581 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656304 CN1CCN(CC2=Cc3ccc(NC(=O)c4ccc(cc4)-c4ccc(Cl)cc4)cc3CC2)CC1 InChI=1S/C29H30ClN3O/c1-32-14-16-33(17-15-32)20-21-2-3-26-19-28(13-10-25(26)18-21)31-29(34)24-6-4-22(5-7-24)23-8-11-27(30)12-9-23/h4-13,18-19H,2-3,14-17,20H2,1H3,(H,31,34) FDETUXPYZUNHKA-UHFFFAOYSA-N 50351314 CHEMBL1818802 Melanin-concentrating hormone receptor 1 Rattus 5.3 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351314&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 21939902 136358000 CHEMBL1818802 ZINC72114582 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656305 CNCC1=Cc2ccc(NC(=O)c3ccc(cc3)-c3ccc(Cl)cc3)cc2CC1 InChI=1S/C25H23ClN2O/c1-27-16-17-2-3-22-15-24(13-10-21(22)14-17)28-25(29)20-6-4-18(5-7-20)19-8-11-23(26)12-9-19/h4-15,27H,2-3,16H2,1H3,(H,28,29) GPXYOCKQAQTLCJ-UHFFFAOYSA-N 50351315 CHEMBL1818803 Melanin-concentrating hormone receptor 1 Rattus 8.5 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351315 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351315&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 56673713 136358001 CHEMBL1818803 ZINC72105497 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656306 CN(CC1=Cc2ccc(NC(=O)c3ccc(cc3)-c3ccc(Cl)cc3)cc2CC1)C(=O)OC(C)(C)C InChI=1S/C30H31ClN2O3/c1-30(2,3)36-29(35)33(4)19-20-5-6-25-18-27(16-13-24(25)17-20)32-28(34)23-9-7-21(8-10-23)22-11-14-26(31)15-12-22/h7-18H,5-6,19H2,1-4H3,(H,32,34) ZVCPPKSMURBTJL-UHFFFAOYSA-N 50351316 CHEMBL1818804 Melanin-concentrating hormone receptor 1 Rattus 250 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351316 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351316&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 56673714 136358002 CHEMBL1818804 ZINC72113775 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656307 CN(CC1=Cc2ccc(NC(=O)c3ccc(cc3)-c3ccc(Cl)cc3)cc2CC1)C(C)=O InChI=1S/C27H25ClN2O2/c1-18(31)30(2)17-19-3-4-24-16-26(14-11-23(24)15-19)29-27(32)22-7-5-20(6-8-22)21-9-12-25(28)13-10-21/h5-16H,3-4,17H2,1-2H3,(H,29,32) NMNBOSLYDRABPP-UHFFFAOYSA-N 50351317 CHEMBL1818805 Melanin-concentrating hormone receptor 1 Rattus 13 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351317 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351317&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 56680348 136358003 CHEMBL1818805 ZINC72113698 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656308 CCC(=O)N(C)CC1=Cc2ccc(NC(=O)c3ccc(cc3)-c3ccc(Cl)cc3)cc2CC1 InChI=1S/C28H27ClN2O2/c1-3-27(32)31(2)18-19-4-5-24-17-26(15-12-23(24)16-19)30-28(33)22-8-6-20(7-9-22)21-10-13-25(29)14-11-21/h6-17H,3-5,18H2,1-2H3,(H,30,33) LWFDTOZBSGDPLO-UHFFFAOYSA-N 50351318 CHEMBL1818806 Melanin-concentrating hormone receptor 1 Rattus 6.2 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351318 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351318&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 56666755 136358004 CHEMBL1818806 ZINC72113699 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656309 CCOC(=O)N(C)CC1=Cc2ccc(NC(=O)c3ccc(cc3)-c3ccc(Cl)cc3)cc2CC1 InChI=1S/C28H27ClN2O3/c1-3-34-28(33)31(2)18-19-4-5-24-17-26(15-12-23(24)16-19)30-27(32)22-8-6-20(7-9-22)21-10-13-25(29)14-11-21/h6-17H,3-5,18H2,1-2H3,(H,30,32) NRJDAIMVDICODS-UHFFFAOYSA-N 50351319 CHEMBL1818807 Melanin-concentrating hormone receptor 1 Rattus 64 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351319 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351319&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 56683679 136358005 CHEMBL1818807 ZINC72118517 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656310 CCNC(=O)N(C)CC1=Cc2ccc(NC(=O)c3ccc(cc3)-c3ccc(Cl)cc3)cc2CC1 InChI=1S/C28H28ClN3O2/c1-3-30-28(34)32(2)18-19-4-5-24-17-26(15-12-23(24)16-19)31-27(33)22-8-6-20(7-9-22)21-10-13-25(29)14-11-21/h6-17H,3-5,18H2,1-2H3,(H,30,34)(H,31,33) ZMPLZHPKJQBOPB-UHFFFAOYSA-N 50351320 CHEMBL1818808 Melanin-concentrating hormone receptor 1 Rattus 70 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351320&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 56666756 136358006 CHEMBL1818808 ZINC72118518 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656311 O=C(Nc1ccc2C=C(CN3CCCC3)CCc2c1)c1ccc(cc1)-c1ccccc1 InChI=1S/C28H28N2O/c31-28(24-12-10-23(11-13-24)22-6-2-1-3-7-22)29-27-15-14-25-18-21(8-9-26(25)19-27)20-30-16-4-5-17-30/h1-3,6-7,10-15,18-19H,4-5,8-9,16-17,20H2,(H,29,31) QQNJJXBJUFOPQJ-UHFFFAOYSA-N 50351321 CHEMBL1818809 Melanin-concentrating hormone receptor 1 Rattus 12 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351321 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351321&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 21940008 136358007 CHEMBL1818809 ZINC72118427 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656312 Cc1ccc(cc1)-c1ccc(cc1)C(=O)Nc1ccc2C=C(CN3CCCC3)CCc2c1 InChI=1S/C29H30N2O/c1-21-4-7-23(8-5-21)24-10-12-25(13-11-24)29(32)30-28-15-14-26-18-22(6-9-27(26)19-28)20-31-16-2-3-17-31/h4-5,7-8,10-15,18-19H,2-3,6,9,16-17,20H2,1H3,(H,30,32) XBNMTFCAASXMHH-UHFFFAOYSA-N 50351322 CHEMBL1818810 Melanin-concentrating hormone receptor 1 Rattus 2.4 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351322 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351322&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 21939898 136358008 CHEMBL1818810 ZINC72118428 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656313 COc1ccc(cc1)-c1ccc(cc1)C(=O)Nc1ccc2C=C(CN3CCCC3)CCc2c1 InChI=1S/C29H30N2O2/c1-33-28-14-11-23(12-15-28)22-6-8-24(9-7-22)29(32)30-27-13-10-25-18-21(4-5-26(25)19-27)20-31-16-2-3-17-31/h6-15,18-19H,2-5,16-17,20H2,1H3,(H,30,32) ANNTXYLVBKCZHB-UHFFFAOYSA-N 50351323 CHEMBL1818811 Melanin-concentrating hormone receptor 1 Rattus 3.7 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351323 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351323&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 21939950 136358009 CHEMBL1818811 ZINC72118429 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656314 Fc1ccc(cc1)-c1ccc(cc1)C(=O)Nc1ccc2C=C(CN3CCCC3)CCc2c1 InChI=1S/C28H27FN2O/c29-26-12-9-22(10-13-26)21-5-7-23(8-6-21)28(32)30-27-14-11-24-17-20(3-4-25(24)18-27)19-31-15-1-2-16-31/h5-14,17-18H,1-4,15-16,19H2,(H,30,32) VHNFRNTVRLAIBR-UHFFFAOYSA-N 50351324 CHEMBL1818901 Melanin-concentrating hormone receptor 1 Rattus 4.1 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351324&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 9910346 136358010 CHEMBL1818901 ZINC34025070 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656315 CN(C)CC1CCc2cc(NC(=O)c3ccc(cc3)-c3ccc(Cl)cc3)ccc2C1 InChI=1S/C26H27ClN2O/c1-29(2)17-18-3-4-23-16-25(14-11-22(23)15-18)28-26(30)21-7-5-19(6-8-21)20-9-12-24(27)13-10-20/h5-14,16,18H,3-4,15,17H2,1-2H3,(H,28,30) BXCOFLLLXKXLRK-UHFFFAOYSA-N 50351297 CHEMBL1818783 Melanin-concentrating hormone receptor 1 Rattus 8.00 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351297 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351297&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 23593464 136357983 CHEMBL1818783 ZINC72113729 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656316 CN(C)CC1CCc2cc(NC(=O)c3ccc(cc3)-c3ccc(Cl)cc3)ccc2C1 InChI=1S/C26H27ClN2O/c1-29(2)17-18-3-4-23-16-25(14-11-22(23)15-18)28-26(30)21-7-5-19(6-8-21)20-9-12-24(27)13-10-20/h5-14,16,18H,3-4,15,17H2,1-2H3,(H,28,30) BXCOFLLLXKXLRK-UHFFFAOYSA-N 50351297 CHEMBL1818783 Melanin-concentrating hormone receptor 1 Rattus 5.30 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351297 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351297&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 23593464 136357983 CHEMBL1818783 ZINC72113729 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656317 Fc1ccc(cc1)-c1ccc(cc1)C(=O)Nc1ccc2C=C(CN3CCCC3)CCc2c1 InChI=1S/C28H27FN2O/c29-26-12-9-22(10-13-26)21-5-7-23(8-6-21)28(32)30-27-14-11-24-17-20(3-4-25(24)18-27)19-31-15-1-2-16-31/h5-14,17-18H,1-4,15-16,19H2,(H,30,32) VHNFRNTVRLAIBR-UHFFFAOYSA-N 50351324 CHEMBL1818901 Melanin-concentrating hormone receptor 1 Rattus 11 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351324&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 9910346 136358010 CHEMBL1818901 ZINC34025070 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50656320 CN(C)CC1CCc2cc(NC(=O)c3ccc(cc3)-c3ccc(Cl)cc3)ccc2C1 InChI=1S/C26H27ClN2O/c1-29(2)17-18-3-4-23-16-25(14-11-22(23)15-18)28-26(30)21-7-5-19(6-8-21)20-9-12-24(27)13-10-20/h5-14,16,18H,3-4,15,17H2,1-2H3,(H,28,30) BXCOFLLLXKXLRK-UHFFFAOYSA-N 50351297 CHEMBL1818783 Melanin-concentrating hormone receptor 1 Rattus 8 ChEMBL 10.1016/j.bmc.2011.07.038 10.7270/Q26H4HT4 21856163 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Terauchi, J; Miyamoto, M; Ora, T; Tawada, M; Endo, S; Takekawa, S; Asami, A; Suzuki, N; Nagisa, Y; Nakano, Y; Watanabe, K; Ogino, H; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50351297 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50351297&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 23593464 136357983 CHEMBL1818783 ZINC72113729 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50702140 CCC(=O)N1CCc2ccc(cc2CC1)C(=O)CCCN1CCC(CC1)c1ccc(Cl)cc1 InChI=1S/C28H35ClN2O2/c1-2-28(33)31-18-13-22-5-6-25(20-24(22)14-19-31)27(32)4-3-15-30-16-11-23(12-17-30)21-7-9-26(29)10-8-21/h5-10,20,23H,2-4,11-19H2,1H3 NZHJHYYMLWBZAI-UHFFFAOYSA-N 50357502 CHEMBL1914631 Melanin-concentrating hormone receptor 1 Rattus 8.4 ChEMBL 10.1016/j.bmc.2011.09.007 10.7270/Q26T0N2H 21975069 Kasai, S; Kamaura, M; Kamata, M; Aso, K; Ogino, H; Nakano, Y; Watanabe, K; Kaisho, T; Tawada, M; Nagisa, Y; Takekawa, S; Kato, K; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50357502 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50357502&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 57398088 136961526 CHEMBL1914631 ZINC73196591 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50702141 CCCC(=O)N1CCc2ccc(cc2CC1)C(=O)CCCN1CCC(CC1)c1ccc(Cl)cc1 InChI=1S/C29H37ClN2O2/c1-2-4-29(34)32-19-14-23-6-7-26(21-25(23)15-20-32)28(33)5-3-16-31-17-12-24(13-18-31)22-8-10-27(30)11-9-22/h6-11,21,24H,2-5,12-20H2,1H3 FIXYNOHWROJUQQ-UHFFFAOYSA-N 50357503 CHEMBL1914632 Melanin-concentrating hormone receptor 1 Rattus 7.5 ChEMBL 10.1016/j.bmc.2011.09.007 10.7270/Q26T0N2H 21975069 Kasai, S; Kamaura, M; Kamata, M; Aso, K; Ogino, H; Nakano, Y; Watanabe, K; Kaisho, T; Tawada, M; Nagisa, Y; Takekawa, S; Kato, K; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50357503 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50357503&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 57392824 136961527 CHEMBL1914632 ZINC73196592 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50702142 Clc1ccc(cc1)C1CCN(CCCC(=O)c2ccc3CCN(CCc3c2)C(=O)C2CC2)CC1 InChI=1S/C29H35ClN2O2/c30-27-9-7-21(8-10-27)23-11-16-31(17-12-23)15-1-2-28(33)26-6-3-22-13-18-32(19-14-25(22)20-26)29(34)24-4-5-24/h3,6-10,20,23-24H,1-2,4-5,11-19H2 YYDVYANRNHFNIC-UHFFFAOYSA-N 50357504 CHEMBL1914633 Melanin-concentrating hormone receptor 1 Rattus 7.3 ChEMBL 10.1016/j.bmc.2011.09.007 10.7270/Q26T0N2H 21975069 Kasai, S; Kamaura, M; Kamata, M; Aso, K; Ogino, H; Nakano, Y; Watanabe, K; Kaisho, T; Tawada, M; Nagisa, Y; Takekawa, S; Kato, K; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50357504 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50357504&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 57399740 136961528 CHEMBL1914633 ZINC73196593 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50702143 CCCCC(=O)N1CCc2ccc(cc2CC1)C(=O)CCCN1CCC(CC1)c1ccc(Cl)cc1 InChI=1S/C30H39ClN2O2/c1-2-3-6-30(35)33-20-15-24-7-8-27(22-26(24)16-21-33)29(34)5-4-17-32-18-13-25(14-19-32)23-9-11-28(31)12-10-23/h7-12,22,25H,2-6,13-21H2,1H3 MAOBSGZTBSXHQB-UHFFFAOYSA-N 50357505 CHEMBL1914634 Melanin-concentrating hormone receptor 1 Rattus 11 ChEMBL 10.1016/j.bmc.2011.09.007 10.7270/Q26T0N2H 21975069 Kasai, S; Kamaura, M; Kamata, M; Aso, K; Ogino, H; Nakano, Y; Watanabe, K; Kaisho, T; Tawada, M; Nagisa, Y; Takekawa, S; Kato, K; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50357505 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50357505&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 57391028 136961529 CHEMBL1914634 ZINC73196257 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50702144 Clc1ccc(cc1)C1CCN(CCCC(=O)c2ccc3CCN(CCc3c2)C(=O)c2ccccc2)CC1 InChI=1S/C32H35ClN2O2/c33-30-12-10-24(11-13-30)26-14-19-34(20-15-26)18-4-7-31(36)29-9-8-25-16-21-35(22-17-28(25)23-29)32(37)27-5-2-1-3-6-27/h1-3,5-6,8-13,23,26H,4,7,14-22H2 ZIYJTXYUZSCVHR-UHFFFAOYSA-N 50357506 CHEMBL1914635 Melanin-concentrating hormone receptor 1 Rattus 79 ChEMBL 10.1016/j.bmc.2011.09.007 10.7270/Q26T0N2H 21975069 Kasai, S; Kamaura, M; Kamata, M; Aso, K; Ogino, H; Nakano, Y; Watanabe, K; Kaisho, T; Tawada, M; Nagisa, Y; Takekawa, S; Kato, K; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50357506 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50357506&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 57401508 136961530 CHEMBL1914635 ZINC73196258 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50702145 CS(=O)(=O)N1CCc2ccc(cc2CC1)C(=O)CCCN1CCC(CC1)c1ccc(Cl)cc1 InChI=1S/C26H33ClN2O3S/c1-33(31,32)29-17-12-21-4-5-24(19-23(21)13-18-29)26(30)3-2-14-28-15-10-22(11-16-28)20-6-8-25(27)9-7-20/h4-9,19,22H,2-3,10-18H2,1H3 PSWKECDRCXIRBL-UHFFFAOYSA-N 50357507 CHEMBL1914636 Melanin-concentrating hormone receptor 1 Rattus 8.5 ChEMBL 10.1016/j.bmc.2011.09.007 10.7270/Q26T0N2H 21975069 Kasai, S; Kamaura, M; Kamata, M; Aso, K; Ogino, H; Nakano, Y; Watanabe, K; Kaisho, T; Tawada, M; Nagisa, Y; Takekawa, S; Kato, K; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50357507 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50357507&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 57401509 136961531 CHEMBL1914636 ZINC73160310 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50702146 CCS(=O)(=O)N1CCc2ccc(cc2CC1)C(=O)CCCN1CCC(CC1)c1ccc(Cl)cc1 InChI=1S/C27H35ClN2O3S/c1-2-34(32,33)30-18-13-22-5-6-25(20-24(22)14-19-30)27(31)4-3-15-29-16-11-23(12-17-29)21-7-9-26(28)10-8-21/h5-10,20,23H,2-4,11-19H2,1H3 LOMPVSFLJSMAAD-UHFFFAOYSA-N 50357508 CHEMBL1914637 Melanin-concentrating hormone receptor 1 Rattus 6.4 ChEMBL 10.1016/j.bmc.2011.09.007 10.7270/Q26T0N2H 21975069 Kasai, S; Kamaura, M; Kamata, M; Aso, K; Ogino, H; Nakano, Y; Watanabe, K; Kaisho, T; Tawada, M; Nagisa, Y; Takekawa, S; Kato, K; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50357508 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50357508&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 57396294 136961532 CHEMBL1914637 ZINC73160318 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50702147 COC(=O)N1CCc2ccc(cc2CC1)C(=O)CCCN1CCC(CC1)c1ccc(Cl)cc1 InChI=1S/C27H33ClN2O3/c1-33-27(32)30-17-12-21-4-5-24(19-23(21)13-18-30)26(31)3-2-14-29-15-10-22(11-16-29)20-6-8-25(28)9-7-20/h4-9,19,22H,2-3,10-18H2,1H3 CPYUEJDJXAFCCN-UHFFFAOYSA-N 50357509 CHEMBL1914638 Melanin-concentrating hormone receptor 1 Rattus 17 ChEMBL 10.1016/j.bmc.2011.09.007 10.7270/Q26T0N2H 21975069 Kasai, S; Kamaura, M; Kamata, M; Aso, K; Ogino, H; Nakano, Y; Watanabe, K; Kaisho, T; Tawada, M; Nagisa, Y; Takekawa, S; Kato, K; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50357509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50357509&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 57399741 136961533 CHEMBL1914638 ZINC73160326 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50702148 CCNC(=O)N1CCc2ccc(cc2CC1)C(=O)CCCN1CCC(CC1)c1ccc(Cl)cc1 InChI=1S/C28H36ClN3O2/c1-2-30-28(34)32-18-13-22-5-6-25(20-24(22)14-19-32)27(33)4-3-15-31-16-11-23(12-17-31)21-7-9-26(29)10-8-21/h5-10,20,23H,2-4,11-19H2,1H3,(H,30,34) AHHLDXACAMZJFP-UHFFFAOYSA-N 50357510 CHEMBL1914639 Melanin-concentrating hormone receptor 1 Rattus 11 ChEMBL 10.1016/j.bmc.2011.09.007 10.7270/Q26T0N2H 21975069 Kasai, S; Kamaura, M; Kamata, M; Aso, K; Ogino, H; Nakano, Y; Watanabe, K; Kaisho, T; Tawada, M; Nagisa, Y; Takekawa, S; Kato, K; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50357510 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50357510&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 57401510 136961534 CHEMBL1914639 ZINC73160334 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50702149 CC(=O)N1CCCc2ccc(cc2C1)C(=O)CCCN1CCC(CC1)c1ccc(Cl)cc1 InChI=1S/C27H33ClN2O2/c1-20(31)30-15-2-4-21-6-7-24(18-25(21)19-30)27(32)5-3-14-29-16-12-23(13-17-29)22-8-10-26(28)11-9-22/h6-11,18,23H,2-5,12-17,19H2,1H3 YTFZTIDQFURVGW-UHFFFAOYSA-N 50357525 CHEMBL1914851 Melanin-concentrating hormone receptor 1 Rattus 86 ChEMBL 10.1016/j.bmc.2011.09.007 10.7270/Q26T0N2H 21975069 Kasai, S; Kamaura, M; Kamata, M; Aso, K; Ogino, H; Nakano, Y; Watanabe, K; Kaisho, T; Tawada, M; Nagisa, Y; Takekawa, S; Kato, K; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50357525 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50357525&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 57391045 136961549 CHEMBL1914851 ZINC73388739 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50702150 CC(=O)N1CCc2ccc(cc2C1)C(=O)CCCN1CCC(CC1)c1ccc(Cl)cc1 InChI=1S/C26H31ClN2O2/c1-19(30)29-16-12-21-4-5-23(17-24(21)18-29)26(31)3-2-13-28-14-10-22(11-15-28)20-6-8-25(27)9-7-20/h4-9,17,22H,2-3,10-16,18H2,1H3 UDQZYDOXQICQED-UHFFFAOYSA-N 50357526 CHEMBL1914852 Melanin-concentrating hormone receptor 1 Rattus 11 ChEMBL 10.1016/j.bmc.2011.09.007 10.7270/Q26T0N2H 21975069 Kasai, S; Kamaura, M; Kamata, M; Aso, K; Ogino, H; Nakano, Y; Watanabe, K; Kaisho, T; Tawada, M; Nagisa, Y; Takekawa, S; Kato, K; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50357526 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50357526&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 56589628 136961550 CHEMBL1914852 ZINC73156209 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50702151 Clc1ccc(cc1)C1CCN(CCCC(=O)c2ccc3CCCCCc3c2)CC1 InChI=1S/C26H32ClNO/c27-25-12-10-21(11-13-25)22-14-17-28(18-15-22)16-4-7-26(29)24-9-8-20-5-2-1-3-6-23(20)19-24/h8-13,19,22H,1-7,14-18H2 ODJZNQUAMUEYPG-UHFFFAOYSA-N 50357530 CHEMBL1914856 Melanin-concentrating hormone receptor 1 Rattus 80 ChEMBL 10.1016/j.bmc.2011.09.007 10.7270/Q26T0N2H 21975069 Kasai, S; Kamaura, M; Kamata, M; Aso, K; Ogino, H; Nakano, Y; Watanabe, K; Kaisho, T; Tawada, M; Nagisa, Y; Takekawa, S; Kato, K; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50357530 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50357530&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 57390252 136961554 CHEMBL1914856 ZINC73169307 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50704960 C[C@@H]1[C@H]2CN(CCCC3CCOCC3)CC[C@@H]2Cc2[nH]c3ccc(cc3c12)C(F)(F)F InChI=1S/C25H33F3N2O/c1-16-21-15-30(9-2-3-17-7-11-31-12-8-17)10-6-18(21)13-23-24(16)20-14-19(25(26,27)28)4-5-22(20)29-23/h4-5,14,16-18,21,29H,2-3,6-13,15H2,1H3/t16-,18-,21-/m1/s1 VGWOOKCYUNUQRH-HGHGUNKESA-N 50358743 CHEMBL1922270 Melanin-concentrating hormone receptor 1 Rattus 4 ChEMBL 10.1016/j.bmcl.2011.09.110 10.7270/Q29887FX 22019296 Mihalic, JT; Chen, X; Fan, P; Chen, X; Fu, Y; Liang, L; Reed, M; Tang, L; Chen, JL; Jaen, J; Li, L; Dai, K Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50358743 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50358743&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11561126 136962767 CHEMBL1922270 ZINC35819304 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50904797 CCO\N=C(\c1ccc(F)c(F)c1)c1ccc(CN2CCC3(CC2)OCc2cn(C)c(=O)cc32)cn1 InChI=1S/C27H28F2N4O3/c1-3-36-31-26(19-5-6-22(28)23(29)12-19)24-7-4-18(14-30-24)15-33-10-8-27(9-11-33)21-13-25(34)32(2)16-20(21)17-35-27/h4-7,12-14,16H,3,8-11,15,17H2,1-2H3/b31-26- FPPIDMVDDSIXTQ-ZXPTYKNPSA-N 50301708 (Z)-1'-((6-((3,4-difluorophenyl)(ethoxyimino)methyl)pyridin-3-yl)methyl)-5-methyl-3H-spiro[furo[3,4-c]pyridine-1,4'-piperidin]-6(5H)-one::CHEMBL585664 Melanin-concentrating hormone receptor 1 Rattus 8.8 ChEMBL 10.1016/j.bmcl.2009.07.132 10.7270/Q27P90BK 19683441 Suzuki, T; Kameda, M; Ando, M; Miyazoe, H; Sekino, E; Ito, S; Masutani, K; Kamijo, K; Takezawa, A; Moriya, M; Ito, M; Ito, J; Nakase, K; Matsushita, H; Ishihara, A; Takenaga, N; Tokita, S; Kanatani, A; Sato, N; Fukami, T Tsukuba Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50301708 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50301708&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 45487653 104156069 CHEMBL585664 ZINC45324362 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50904803 CC(C)C(=O)Nc1cccc(c1)C1CCN(Cc2ccc(Oc3ccc(F)c(F)c3)cc2)CC1 InChI=1S/C28H30F2N2O2/c1-19(2)28(33)31-23-5-3-4-22(16-23)21-12-14-32(15-13-21)18-20-6-8-24(9-7-20)34-25-10-11-26(29)27(30)17-25/h3-11,16-17,19,21H,12-15,18H2,1-2H3,(H,31,33) MJDBJIACJNGVIM-UHFFFAOYSA-N 50219047 CHEMBL245231::N-(3-(1-(4-(3,4-difluorophenoxy)benzyl)piperidin-4-yl)phenyl)isobutyramide::N-(3-{1-[4-(3,4-difluorophenoxy)benzyl]-4-piperidinyl}phenyl)-2-methylpropanamide Melanin-concentrating hormone receptor 1 Rattus 1.8 ChEMBL 10.1016/j.bmcl.2009.07.132 10.7270/Q27P90BK 19683441 Suzuki, T; Kameda, M; Ando, M; Miyazoe, H; Sekino, E; Ito, S; Masutani, K; Kamijo, K; Takezawa, A; Moriya, M; Ito, M; Ito, J; Nakase, K; Matsushita, H; Ishihara, A; Takenaga, N; Tokita, S; Kanatani, A; Sato, N; Fukami, T Tsukuba Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219047&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10183297 104092439 CHEMBL245231 ZINC28710589 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50933786 Cc1c(NC(=O)c2ccc(cc2)-c2ccc(F)cc2)ccc2cc(CN3CCCC3)cnc12 InChI=1S/C28H26FN3O/c1-19-26(13-10-24-16-20(17-30-27(19)24)18-32-14-2-3-15-32)31-28(33)23-6-4-21(5-7-23)22-8-11-25(29)12-9-22/h4-13,16-17H,2-3,14-15,18H2,1H3,(H,31,33) BSQRGMOOEUYKJQ-UHFFFAOYSA-N 50383112 CHEMBL2029372 Melanin-concentrating hormone receptor 1 Rattus 1.7 ChEMBL 10.1021/jm201596h 10.7270/Q2GH9JZQ 22309223 Kamata, M; Yamashita, T; Imaeda, T; Tanaka, T; Masada, S; Kamaura, M; Kasai, S; Hara, R; Sasaki, S; Takekawa, S; Asami, A; Kaisho, T; Suzuki, N; Ashina, S; Ogino, H; Nakano, Y; Nagisa, Y; Kato, K; Kato, K; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50383112 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50383112&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 9932896 160862195 CHEMBL2029372 ZINC84652328 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50934775 C[C@@H]1[C@H]2CN(CCC3(CCCCC3)C(O)=O)CC[C@@H]2Cc2[nH]c3ccc(cc3c12)C(F)(F)F InChI=1S/C26H33F3N2O2/c1-16-20-15-31(12-10-25(24(32)33)8-3-2-4-9-25)11-7-17(20)13-22-23(16)19-14-18(26(27,28)29)5-6-21(19)30-22/h5-6,14,16-17,20,30H,2-4,7-13,15H2,1H3,(H,32,33)/t16-,17-,20-/m1/s1 WAOZNBXSEVIAGX-MBOZVWFJSA-N 50383522 CHEMBL2032049 Melanin-concentrating hormone receptor 1 Rattus 0.8 ChEMBL 10.1016/j.bmcl.2012.04.006 10.7270/Q2542PMN 22542010 Mihalic, JT; Fan, P; Chen, X; Chen, X; Fu, Y; Motani, A; Liang, L; Lindstrom, M; Tang, L; Chen, JL; Jaen, J; Dai, K; Li, L Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50383522 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50383522&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 10004545 160862605 CHEMBL2032049 ZINC34074273 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50954117 C[C@@H](CNCc1ccccc1)N1C[C@H](CCCN=C(N)N)N(CCc2cccc(F)c2)C1=S InChI=1S/C25H35FN6S/c1-19(16-29-17-21-7-3-2-4-8-21)32-18-23(11-6-13-30-24(27)28)31(25(32)33)14-12-20-9-5-10-22(26)15-20/h2-5,7-10,15,19,23,29H,6,11-14,16-18H2,1H3,(H4,27,28,30)/t19-,23-/m0/s1 DSJVYEAOYVHUJW-CVDCTZTESA-N 50391543 CHEMBL2147477 Melanin-concentrating hormone receptor 1 Rattus 6.1 ChEMBL 10.1016/j.bmcl.2012.08.025 10.7270/Q2T72JHK 22954736 Hogberg, T; Frimurer, TM; Sasmal, PK Leo Pharma A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391543&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11305934 163340567 CHEMBL2147477 ZINC43203998 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50946654 Cc1c(NC(=O)c2ccc(cc2)-c2ccc(F)cc2)ccc2cc(CN3CCCC3)cnc12 InChI=1S/C28H26FN3O/c1-19-26(13-10-24-16-20(17-30-27(19)24)18-32-14-2-3-15-32)31-28(33)23-6-4-21(5-7-23)22-8-11-25(29)12-9-22/h4-13,16-17H,2-3,14-15,18H2,1H3,(H,31,33) BSQRGMOOEUYKJQ-UHFFFAOYSA-N 50383112 CHEMBL2029372 Melanin-concentrating hormone receptor 1 Rattus 1 ChEMBL 10.1021/jm300167z 10.7270/Q2JS9RHR 22490048 Kasai, S; Kamata, M; Masada, S; Kunitomo, J; Kamaura, M; Okawa, T; Takami, K; Ogino, H; Nakano, Y; Ashina, S; Watanabe, K; Kaisho, T; Imai, YN; Ryu, S; Nakayama, M; Nagisa, Y; Takekawa, S; Kato, K; Murata, T; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50383112 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50383112&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 9932896 160862195 CHEMBL2029372 ZINC84652328 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50946655 CCCCOc1ccc(cc1)C(=O)Nc1ccc2cc(CN3CCCC3)cnc2c1C InChI=1S/C26H31N3O2/c1-3-4-15-31-23-10-7-21(8-11-23)26(30)28-24-12-9-22-16-20(17-27-25(22)19(24)2)18-29-13-5-6-14-29/h7-12,16-17H,3-6,13-15,18H2,1-2H3,(H,28,30) ZLQXQZSAJCOABZ-UHFFFAOYSA-N 50388442 CHEMBL2059408 Melanin-concentrating hormone receptor 1 Rattus 1.2 ChEMBL 10.1021/jm300167z 10.7270/Q2JS9RHR 22490048 Kasai, S; Kamata, M; Masada, S; Kunitomo, J; Kamaura, M; Okawa, T; Takami, K; Ogino, H; Nakano, Y; Ashina, S; Watanabe, K; Kaisho, T; Imai, YN; Ryu, S; Nakayama, M; Nagisa, Y; Takekawa, S; Kato, K; Murata, T; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50388442 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50388442&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 18436038 160867525 CHEMBL2059408 ZINC84689249 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50946656 Cc1c(NC(=O)c2ccc(OCC3CC3)cc2)ccc2cc(CN3CCCC3)cnc12 InChI=1S/C26H29N3O2/c1-18-24(28-26(30)21-6-9-23(10-7-21)31-17-19-4-5-19)11-8-22-14-20(15-27-25(18)22)16-29-12-2-3-13-29/h6-11,14-15,19H,2-5,12-13,16-17H2,1H3,(H,28,30) WDJYCRBJWBJLKO-UHFFFAOYSA-N 50388443 CHEMBL2059409 Melanin-concentrating hormone receptor 1 Rattus 1.6 ChEMBL 10.1021/jm300167z 10.7270/Q2JS9RHR 22490048 Kasai, S; Kamata, M; Masada, S; Kunitomo, J; Kamaura, M; Okawa, T; Takami, K; Ogino, H; Nakano, Y; Ashina, S; Watanabe, K; Kaisho, T; Imai, YN; Ryu, S; Nakayama, M; Nagisa, Y; Takekawa, S; Kato, K; Murata, T; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50388443 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50388443&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 18435902 160867526 CHEMBL2059409 ZINC84705001 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50946657 Cc1c(NC(=O)c2ccc(OCCC3CC3)cc2)ccc2cc(CN3CCCC3)cnc12 InChI=1S/C27H31N3O2/c1-19-25(11-8-23-16-21(17-28-26(19)23)18-30-13-2-3-14-30)29-27(31)22-6-9-24(10-7-22)32-15-12-20-4-5-20/h6-11,16-17,20H,2-5,12-15,18H2,1H3,(H,29,31) GNOUTRNRKMHDGH-UHFFFAOYSA-N 50388444 CHEMBL2059410 Melanin-concentrating hormone receptor 1 Rattus 2 ChEMBL 10.1021/jm300167z 10.7270/Q2JS9RHR 22490048 Kasai, S; Kamata, M; Masada, S; Kunitomo, J; Kamaura, M; Okawa, T; Takami, K; Ogino, H; Nakano, Y; Ashina, S; Watanabe, K; Kaisho, T; Imai, YN; Ryu, S; Nakayama, M; Nagisa, Y; Takekawa, S; Kato, K; Murata, T; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50388444 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50388444&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 57522703 160867527 CHEMBL2059410 ZINC84705005 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50946658 CC(C)COc1ccc(cc1)C(=O)Nc1ccc2cc(CN3CCCC3)cnc2c1C InChI=1S/C26H31N3O2/c1-18(2)17-31-23-9-6-21(7-10-23)26(30)28-24-11-8-22-14-20(15-27-25(22)19(24)3)16-29-12-4-5-13-29/h6-11,14-15,18H,4-5,12-13,16-17H2,1-3H3,(H,28,30) ZLLKIIUCLYZWHE-UHFFFAOYSA-N 50388445 CHEMBL2059411 Melanin-concentrating hormone receptor 1 Rattus 6.7 ChEMBL 10.1021/jm300167z 10.7270/Q2JS9RHR 22490048 Kasai, S; Kamata, M; Masada, S; Kunitomo, J; Kamaura, M; Okawa, T; Takami, K; Ogino, H; Nakano, Y; Ashina, S; Watanabe, K; Kaisho, T; Imai, YN; Ryu, S; Nakayama, M; Nagisa, Y; Takekawa, S; Kato, K; Murata, T; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50388445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50388445&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 57522704 160867528 CHEMBL2059411 ZINC84687484 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50946659 CCCCC(=O)Nc1ccc(cc1)C(=O)Nc1ccc2cc(CN3CCCC3)cnc2c1C InChI=1S/C27H32N4O2/c1-3-4-7-25(32)29-23-11-8-21(9-12-23)27(33)30-24-13-10-22-16-20(17-28-26(22)19(24)2)18-31-14-5-6-15-31/h8-13,16-17H,3-7,14-15,18H2,1-2H3,(H,29,32)(H,30,33) FFGSJFHRDGBOBX-UHFFFAOYSA-N 50388446 CHEMBL2059414 Melanin-concentrating hormone receptor 1 Rattus 90 ChEMBL 10.1021/jm300167z 10.7270/Q2JS9RHR 22490048 Kasai, S; Kamata, M; Masada, S; Kunitomo, J; Kamaura, M; Okawa, T; Takami, K; Ogino, H; Nakano, Y; Ashina, S; Watanabe, K; Kaisho, T; Imai, YN; Ryu, S; Nakayama, M; Nagisa, Y; Takekawa, S; Kato, K; Murata, T; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50388446 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50388446&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 23022394 160867529 CHEMBL2059414 ZINC84687806 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50946660 Cc1c(NC(=O)CCCC(=O)c2ccc(F)cc2)ccc2cc(CN3CCCC3)cnc12 InChI=1S/C26H28FN3O2/c1-18-23(29-25(32)6-4-5-24(31)20-7-10-22(27)11-8-20)12-9-21-15-19(16-28-26(18)21)17-30-13-2-3-14-30/h7-12,15-16H,2-6,13-14,17H2,1H3,(H,29,32) BVCRMRCQDWCOLS-UHFFFAOYSA-N 50388447 CHEMBL2059415 Melanin-concentrating hormone receptor 1 Rattus 12 ChEMBL 10.1021/jm300167z 10.7270/Q2JS9RHR 22490048 Kasai, S; Kamata, M; Masada, S; Kunitomo, J; Kamaura, M; Okawa, T; Takami, K; Ogino, H; Nakano, Y; Ashina, S; Watanabe, K; Kaisho, T; Imai, YN; Ryu, S; Nakayama, M; Nagisa, Y; Takekawa, S; Kato, K; Murata, T; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50388447 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50388447&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 23022509 160867530 CHEMBL2059415 ZINC84687807 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50946661 Cc1c(NC(=O)CCCCc2ccc(F)cc2)ccc2cc(CN3CCCC3)cnc12 InChI=1S/C26H30FN3O/c1-19-24(29-25(31)7-3-2-6-20-8-11-23(27)12-9-20)13-10-22-16-21(17-28-26(19)22)18-30-14-4-5-15-30/h8-13,16-17H,2-7,14-15,18H2,1H3,(H,29,31) USBRYOLVHLYFPX-UHFFFAOYSA-N 50388448 CHEMBL2059416 Melanin-concentrating hormone receptor 1 Rattus 12 ChEMBL 10.1021/jm300167z 10.7270/Q2JS9RHR 22490048 Kasai, S; Kamata, M; Masada, S; Kunitomo, J; Kamaura, M; Okawa, T; Takami, K; Ogino, H; Nakano, Y; Ashina, S; Watanabe, K; Kaisho, T; Imai, YN; Ryu, S; Nakayama, M; Nagisa, Y; Takekawa, S; Kato, K; Murata, T; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50388448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50388448&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 18436119 160867531 CHEMBL2059416 ZINC84671665 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50946662 CC1CCCN1Cc1cnc2c(C)c(NC(=O)c3ccc(OCC4CC4)cc3)ccc2c1 InChI=1S/C27H31N3O2/c1-18-4-3-13-30(18)16-21-14-23-9-12-25(19(2)26(23)28-15-21)29-27(31)22-7-10-24(11-8-22)32-17-20-5-6-20/h7-12,14-15,18,20H,3-6,13,16-17H2,1-2H3,(H,29,31) AQKXMQBBHLZKDC-UHFFFAOYSA-N 50388449 CHEMBL2059417 Melanin-concentrating hormone receptor 1 Rattus 6.7 ChEMBL 10.1021/jm300167z 10.7270/Q2JS9RHR 22490048 Kasai, S; Kamata, M; Masada, S; Kunitomo, J; Kamaura, M; Okawa, T; Takami, K; Ogino, H; Nakano, Y; Ashina, S; Watanabe, K; Kaisho, T; Imai, YN; Ryu, S; Nakayama, M; Nagisa, Y; Takekawa, S; Kato, K; Murata, T; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50388449 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50388449&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 57522816 160867532 CHEMBL2059417 ZINC84729829 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50946663 CC(N1CCCC1)c1cnc2c(C)c(NC(=O)c3ccc(OCC4CC4)cc3)ccc2c1 InChI=1S/C27H31N3O2/c1-18-25(29-27(31)21-7-10-24(11-8-21)32-17-20-5-6-20)12-9-22-15-23(16-28-26(18)22)19(2)30-13-3-4-14-30/h7-12,15-16,19-20H,3-6,13-14,17H2,1-2H3,(H,29,31) DFWKNBVJNXPUBW-UHFFFAOYSA-N 50388450 CHEMBL2059418 Melanin-concentrating hormone receptor 1 Rattus 4.2 ChEMBL 10.1021/jm300167z 10.7270/Q2JS9RHR 22490048 Kasai, S; Kamata, M; Masada, S; Kunitomo, J; Kamaura, M; Okawa, T; Takami, K; Ogino, H; Nakano, Y; Ashina, S; Watanabe, K; Kaisho, T; Imai, YN; Ryu, S; Nakayama, M; Nagisa, Y; Takekawa, S; Kato, K; Murata, T; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50388450 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50388450&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 23022536 160867533 CHEMBL2059418 ZINC84705131 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50946664 C[C@H](N1CCCC1)c1cnc2c(C)c(NC(=O)c3ccc(OCC4CC4)cc3)ccc2c1 InChI=1S/C27H31N3O2/c1-18-25(29-27(31)21-7-10-24(11-8-21)32-17-20-5-6-20)12-9-22-15-23(16-28-26(18)22)19(2)30-13-3-4-14-30/h7-12,15-16,19-20H,3-6,13-14,17H2,1-2H3,(H,29,31)/t19-/m0/s1 DFWKNBVJNXPUBW-IBGZPJMESA-N 50388451 CHEMBL2059419 Melanin-concentrating hormone receptor 1 Rattus 8 ChEMBL 10.1021/jm300167z 10.7270/Q2JS9RHR 22490048 Kasai, S; Kamata, M; Masada, S; Kunitomo, J; Kamaura, M; Okawa, T; Takami, K; Ogino, H; Nakano, Y; Ashina, S; Watanabe, K; Kaisho, T; Imai, YN; Ryu, S; Nakayama, M; Nagisa, Y; Takekawa, S; Kato, K; Murata, T; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50388451 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50388451&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 57522945 160867534 CHEMBL2059419 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50946665 C[C@@H](N1CCCC1)c1cnc2c(C)c(NC(=O)c3ccc(OCC4CC4)cc3)ccc2c1 InChI=1S/C27H31N3O2/c1-18-25(29-27(31)21-7-10-24(11-8-21)32-17-20-5-6-20)12-9-22-15-23(16-28-26(18)22)19(2)30-13-3-4-14-30/h7-12,15-16,19-20H,3-6,13-14,17H2,1-2H3,(H,29,31)/t19-/m1/s1 DFWKNBVJNXPUBW-LJQANCHMSA-N 50388452 CHEMBL2059420 Melanin-concentrating hormone receptor 1 Rattus 1.9 ChEMBL 10.1021/jm300167z 10.7270/Q2JS9RHR 22490048 Kasai, S; Kamata, M; Masada, S; Kunitomo, J; Kamaura, M; Okawa, T; Takami, K; Ogino, H; Nakano, Y; Ashina, S; Watanabe, K; Kaisho, T; Imai, YN; Ryu, S; Nakayama, M; Nagisa, Y; Takekawa, S; Kato, K; Murata, T; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50388452 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50388452&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 57521365 160867535 CHEMBL2059420 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50946666 CC(N1CCCCC1)c1cnc2c(C)c(NC(=O)c3ccc(OCC4CC4)cc3)ccc2c1 InChI=1S/C28H33N3O2/c1-19-26(30-28(32)22-8-11-25(12-9-22)33-18-21-6-7-21)13-10-23-16-24(17-29-27(19)23)20(2)31-14-4-3-5-15-31/h8-13,16-17,20-21H,3-7,14-15,18H2,1-2H3,(H,30,32) RJUBOKLKRKNIFB-UHFFFAOYSA-N 50388453 CHEMBL2059421 Melanin-concentrating hormone receptor 1 Rattus 8.3 ChEMBL 10.1021/jm300167z 10.7270/Q2JS9RHR 22490048 Kasai, S; Kamata, M; Masada, S; Kunitomo, J; Kamaura, M; Okawa, T; Takami, K; Ogino, H; Nakano, Y; Ashina, S; Watanabe, K; Kaisho, T; Imai, YN; Ryu, S; Nakayama, M; Nagisa, Y; Takekawa, S; Kato, K; Murata, T; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50388453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50388453&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 57522946 160867536 CHEMBL2059421 ZINC84705135 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50946667 CC(N1CCCCCC1)c1cnc2c(C)c(NC(=O)c3ccc(OCC4CC4)cc3)ccc2c1 InChI=1S/C29H35N3O2/c1-20-27(31-29(33)23-9-12-26(13-10-23)34-19-22-7-8-22)14-11-24-17-25(18-30-28(20)24)21(2)32-15-5-3-4-6-16-32/h9-14,17-18,21-22H,3-8,15-16,19H2,1-2H3,(H,31,33) IFEFDWUIXYPIMI-UHFFFAOYSA-N 50388454 CHEMBL2059422 Melanin-concentrating hormone receptor 1 Rattus 5.6 ChEMBL 10.1021/jm300167z 10.7270/Q2JS9RHR 22490048 Kasai, S; Kamata, M; Masada, S; Kunitomo, J; Kamaura, M; Okawa, T; Takami, K; Ogino, H; Nakano, Y; Ashina, S; Watanabe, K; Kaisho, T; Imai, YN; Ryu, S; Nakayama, M; Nagisa, Y; Takekawa, S; Kato, K; Murata, T; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50388454 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50388454&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 57522947 160867537 CHEMBL2059422 ZINC84705139 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50946668 CC(N1CCN(C)CC1)c1cnc2c(C)c(NC(=O)c3ccc(OCC4CC4)cc3)ccc2c1 InChI=1S/C28H34N4O2/c1-19-26(30-28(33)22-6-9-25(10-7-22)34-18-21-4-5-21)11-8-23-16-24(17-29-27(19)23)20(2)32-14-12-31(3)13-15-32/h6-11,16-17,20-21H,4-5,12-15,18H2,1-3H3,(H,30,33) GCVIBCLEAUEYBP-UHFFFAOYSA-N 50388455 CHEMBL2059423 Melanin-concentrating hormone receptor 1 Rattus 20 ChEMBL 10.1021/jm300167z 10.7270/Q2JS9RHR 22490048 Kasai, S; Kamata, M; Masada, S; Kunitomo, J; Kamaura, M; Okawa, T; Takami, K; Ogino, H; Nakano, Y; Ashina, S; Watanabe, K; Kaisho, T; Imai, YN; Ryu, S; Nakayama, M; Nagisa, Y; Takekawa, S; Kato, K; Murata, T; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50388455 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50388455&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 57522948 160867538 CHEMBL2059423 ZINC84688165 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50946669 CC(N1CC[C@H](O)C1)c1cnc2c(C)c(NC(=O)c3ccc(OCC4CC4)cc3)ccc2c1 InChI=1S/C27H31N3O3/c1-17-25(29-27(32)20-5-8-24(9-6-20)33-16-19-3-4-19)10-7-21-13-22(14-28-26(17)21)18(2)30-12-11-23(31)15-30/h5-10,13-14,18-19,23,31H,3-4,11-12,15-16H2,1-2H3,(H,29,32)/t18?,23-/m0/s1 JSVWEGWBBVUOER-IMMUGOHXSA-N 50388456 CHEMBL2059424 Melanin-concentrating hormone receptor 1 Rattus 19 ChEMBL 10.1021/jm300167z 10.7270/Q2JS9RHR 22490048 Kasai, S; Kamata, M; Masada, S; Kunitomo, J; Kamaura, M; Okawa, T; Takami, K; Ogino, H; Nakano, Y; Ashina, S; Watanabe, K; Kaisho, T; Imai, YN; Ryu, S; Nakayama, M; Nagisa, Y; Takekawa, S; Kato, K; Murata, T; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50388456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50388456&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 57522949 160867539 CHEMBL2059424 ZINC84688167 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50946670 CC(NCC(C)(C)O)c1cnc2c(C)c(NC(=O)c3ccc(OCC4CC4)cc3)ccc2c1 InChI=1S/C27H33N3O3/c1-17-24(30-26(31)20-7-10-23(11-8-20)33-15-19-5-6-19)12-9-21-13-22(14-28-25(17)21)18(2)29-16-27(3,4)32/h7-14,18-19,29,32H,5-6,15-16H2,1-4H3,(H,30,31) MRIYVMHCGWNLAX-UHFFFAOYSA-N 50388457 CHEMBL2059426 Melanin-concentrating hormone receptor 1 Rattus 2.7 ChEMBL 10.1021/jm300167z 10.7270/Q2JS9RHR 22490048 Kasai, S; Kamata, M; Masada, S; Kunitomo, J; Kamaura, M; Okawa, T; Takami, K; Ogino, H; Nakano, Y; Ashina, S; Watanabe, K; Kaisho, T; Imai, YN; Ryu, S; Nakayama, M; Nagisa, Y; Takekawa, S; Kato, K; Murata, T; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50388457 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50388457&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 57523086 160867540 CHEMBL2059426 ZINC84671955 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50946671 CC(NCCNC(C)=O)c1cnc2c(C)c(NC(=O)c3ccc(OCC4CC4)cc3)ccc2c1 InChI=1S/C27H32N4O3/c1-17-25(31-27(33)21-6-9-24(10-7-21)34-16-20-4-5-20)11-8-22-14-23(15-30-26(17)22)18(2)28-12-13-29-19(3)32/h6-11,14-15,18,20,28H,4-5,12-13,16H2,1-3H3,(H,29,32)(H,31,33) HRYQXLHGNOJEHH-UHFFFAOYSA-N 50388458 CHEMBL2059511 Melanin-concentrating hormone receptor 1 Rattus 3.4 ChEMBL 10.1021/jm300167z 10.7270/Q2JS9RHR 22490048 Kasai, S; Kamata, M; Masada, S; Kunitomo, J; Kamaura, M; Okawa, T; Takami, K; Ogino, H; Nakano, Y; Ashina, S; Watanabe, K; Kaisho, T; Imai, YN; Ryu, S; Nakayama, M; Nagisa, Y; Takekawa, S; Kato, K; Murata, T; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50388458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50388458&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 57522468 160867541 CHEMBL2059511 ZINC84688209 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50946672 C[C@H](NCCNC(C)=O)c1cnc2c(C)c(NC(=O)c3ccc(OCC4CC4)cc3)ccc2c1 InChI=1S/C27H32N4O3/c1-17-25(31-27(33)21-6-9-24(10-7-21)34-16-20-4-5-20)11-8-22-14-23(15-30-26(17)22)18(2)28-12-13-29-19(3)32/h6-11,14-15,18,20,28H,4-5,12-13,16H2,1-3H3,(H,29,32)(H,31,33)/t18-/m0/s1 HRYQXLHGNOJEHH-SFHVURJKSA-N 50388459 CHEMBL2059512 Melanin-concentrating hormone receptor 1 Rattus 12 ChEMBL 10.1021/jm300167z 10.7270/Q2JS9RHR 22490048 Kasai, S; Kamata, M; Masada, S; Kunitomo, J; Kamaura, M; Okawa, T; Takami, K; Ogino, H; Nakano, Y; Ashina, S; Watanabe, K; Kaisho, T; Imai, YN; Ryu, S; Nakayama, M; Nagisa, Y; Takekawa, S; Kato, K; Murata, T; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50388459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50388459&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 57521366 160867542 CHEMBL2059512 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50946673 C[C@@H](NCCNC(C)=O)c1cnc2c(C)c(NC(=O)c3ccc(OCC4CC4)cc3)ccc2c1 InChI=1S/C27H32N4O3/c1-17-25(31-27(33)21-6-9-24(10-7-21)34-16-20-4-5-20)11-8-22-14-23(15-30-26(17)22)18(2)28-12-13-29-19(3)32/h6-11,14-15,18,20,28H,4-5,12-13,16H2,1-3H3,(H,29,32)(H,31,33)/t18-/m1/s1 HRYQXLHGNOJEHH-GOSISDBHSA-N 50388460 CHEMBL2059513 Melanin-concentrating hormone receptor 1 Rattus 2.4 ChEMBL 10.1021/jm300167z 10.7270/Q2JS9RHR 22490048 Kasai, S; Kamata, M; Masada, S; Kunitomo, J; Kamaura, M; Okawa, T; Takami, K; Ogino, H; Nakano, Y; Ashina, S; Watanabe, K; Kaisho, T; Imai, YN; Ryu, S; Nakayama, M; Nagisa, Y; Takekawa, S; Kato, K; Murata, T; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50388460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50388460&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 57523087 160867543 CHEMBL2059513 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50946674 Cc1c(NC(=O)c2ccc(OCC3CC3)cc2)ccc2cc(cnc12)C(C)(C)N1CCCC1 InChI=1S/C28H33N3O2/c1-19-25(30-27(32)21-8-11-24(12-9-21)33-18-20-6-7-20)13-10-22-16-23(17-29-26(19)22)28(2,3)31-14-4-5-15-31/h8-13,16-17,20H,4-7,14-15,18H2,1-3H3,(H,30,32) TVRAIZHTLABDDY-UHFFFAOYSA-N 50388441 CHEMBL2059514 Melanin-concentrating hormone receptor 1 Rattus 8.3 ChEMBL 10.1021/jm300167z 10.7270/Q2JS9RHR 22490048 Kasai, S; Kamata, M; Masada, S; Kunitomo, J; Kamaura, M; Okawa, T; Takami, K; Ogino, H; Nakano, Y; Ashina, S; Watanabe, K; Kaisho, T; Imai, YN; Ryu, S; Nakayama, M; Nagisa, Y; Takekawa, S; Kato, K; Murata, T; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50388441 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50388441&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 57522701 160867524 CHEMBL2059514 ZINC84705172 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 50946688 CC(NCCO)c1cnc2c(C)c(NC(=O)c3ccc(OCC4CC4)cc3)ccc2c1 InChI=1S/C25H29N3O3/c1-16-23(10-7-20-13-21(14-27-24(16)20)17(2)26-11-12-29)28-25(30)19-5-8-22(9-6-19)31-15-18-3-4-18/h5-10,13-14,17-18,26,29H,3-4,11-12,15H2,1-2H3,(H,28,30) LGVJSFVTVWXIFE-UHFFFAOYSA-N 50388461 CHEMBL2059425 Melanin-concentrating hormone receptor 1 Rattus 13 ChEMBL 10.1021/jm300167z 10.7270/Q2JS9RHR 22490048 Kasai, S; Kamata, M; Masada, S; Kunitomo, J; Kamaura, M; Okawa, T; Takami, K; Ogino, H; Nakano, Y; Ashina, S; Watanabe, K; Kaisho, T; Imai, YN; Ryu, S; Nakayama, M; Nagisa, Y; Takekawa, S; Kato, K; Murata, T; Suzuki, N; Ishihara, Y Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50388461 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50388461&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 57522950 160867544 CHEMBL2059425 ZINC84671953 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 51003931 Clc1ccc(CN2CCC[C@H]2CNC(=O)Cc2csc3ccccc23)cc1Cl InChI=1S/C22H22Cl2N2OS/c23-19-8-7-15(10-20(19)24)13-26-9-3-4-17(26)12-25-22(27)11-16-14-28-21-6-2-1-5-18(16)21/h1-2,5-8,10,14,17H,3-4,9,11-13H2,(H,25,27)/t17-/m0/s1 ZGXXRCHPJRBHFM-KRWDZBQOSA-N 50411328 CHEMBL2096864 Melanin-concentrating hormone receptor 1 Rattus 6000 ChEMBL 10.1021/jm040084c 10.7270/Q2280737 15615535 Lavrador, K; Murphy, B; Saunders, J; Struthers, S; Wang, X; Williams, J Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50411328 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50411328&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11192044 163360352 CHEMBL2096864 ZINC13586766 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3 51003932 O=C(CCCc1ccccc1)NC[C@@H]1CCCN1CCc1ccccc1 InChI=1S/C23H30N2O/c26-23(15-7-13-20-9-3-1-4-10-20)24-19-22-14-8-17-25(22)18-16-21-11-5-2-6-12-21/h1-6,9-12,22H,7-8,13-19H2,(H,24,26)/t22-/m0/s1 HFTIKXYSNDRVRI-QFIPXVFZSA-N 50411329 CHEMBL2096865 Melanin-concentrating hormone receptor 1 Rattus >10000 ChEMBL 10.1021/jm040084c 10.7270/Q2280737 15615535 Lavrador, K; Murphy, B; Saunders, J; Struthers, S; Wang, X; Williams, J Neurocrine Biosciences Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50411329 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000716&target=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50411329&enzyme=Melanin-concentrating+hormone+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 11202105 163360353 CHEMBL2096865 ZINC13586768 1 MDLQTSLLSTGPNASNISDGQDNLTLPGSPPRTGSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMTIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT Melanin-concentrating hormone receptor 1 MCHR1_RAT P97639 A0A140TAD3