BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 163281 NCCc1c[nH]c2ccccc12 InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2 APJYDQYYACXCRM-UHFFFAOYSA-N 50024210 1H-indole-3-ethanamine::2-(1H-indol-3-yl)ethanamine::2-(3-indolyl)ethylamine::CHEMBL6640::tryptamine 5-hydroxytryptamine receptor 4 Mus musculus >10000 PDSP Ki 10.7270/Q28G8J68 8226867 Bard, JA; Zgombick, J; Adham, N; Vaysse, P; Branchek, TA; Weinshank, RL Synaptic Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024210 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024210&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search TSS 2IUQ,3RXI,7WBA,2FPB,6KHP,6HTM,4GE1,2PQL,3ATM,7JU0,2AGW,8EEH 1150 103934501 16765 CHEMBL6640 DB08653 125 C00398 ZINC00120144 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172429 NCCc1c[nH]c2ccc(O)cc12 InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 QZAYGJVTTNCVMB-UHFFFAOYSA-N 10755 14C-5-hydroxy tryptamine creatinine disulfate::2-imino-1-methylimidazolidin-4-one; 3-(2-aminoethyl)-1H-indol-5-ol; bis(sulfuric acid)::5-HT::5-Hydroxy Tryptamine::5-hydroxy tryptamine creatinine disulfate::CHEMBL535832::Serotonin::[3H]-5-HT 5-hydroxytryptamine receptor 4 Mus musculus 79.43 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10755&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search SRO 7WB7,7CFP,7BS9,3Q6K,3ADV,7YS6,6DG8,6DG7,7E2Y,7CFQ,2YMD,5MT3,5MT9,7TX8,7LI9,7LIA,6Y5A,7WC4,5MAM,6HIO,6HIN,6HIQ,7E32,3NK1,6KHN,2QEH,7BS2,3BRN,7MGW,4DUF,4DUE,7DAL,4DTW,7XTA,7XTB,7XT9,7XT8 5202 172097186 28790 CHEMBL535832 C00780 ZINC00057058 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172430 NCCc1c[nH]c2ccc(O)cc12 InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 QZAYGJVTTNCVMB-UHFFFAOYSA-N 10755 14C-5-hydroxy tryptamine creatinine disulfate::2-imino-1-methylimidazolidin-4-one; 3-(2-aminoethyl)-1H-indol-5-ol; bis(sulfuric acid)::5-HT::5-Hydroxy Tryptamine::5-hydroxy tryptamine creatinine disulfate::CHEMBL535832::Serotonin::[3H]-5-HT 5-hydroxytryptamine receptor 4 Mus musculus 79.43 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10755&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search SRO 7WB7,7CFP,7BS9,3Q6K,3ADV,7YS6,6DG8,6DG7,7E2Y,7CFQ,2YMD,5MT3,5MT9,7TX8,7LI9,7LIA,6Y5A,7WC4,5MAM,6HIO,6HIN,6HIQ,7E32,3NK1,6KHN,2QEH,7BS2,3BRN,7MGW,4DUF,4DUE,7DAL,4DTW,7XTA,7XTB,7XT9,7XT8 5202 172097186 28790 CHEMBL535832 C00780 ZINC00057058 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172433 COc1ccc2[nH]cc(CCN)c2c1 InChI=1S/C11H14N2O/c1-14-9-2-3-11-10(6-9)8(4-5-12)7-13-11/h2-3,6-7,13H,4-5,12H2,1H3 JTEJPPKMYBDEMY-UHFFFAOYSA-N 82087 2-(5-methoxy-1H-indol-3-yl)ethanamine::5-MT::5-Methoxytryptamine hydrochloride::CAS_66-83-1::tryptamine, 5-Methoxy 5-hydroxytryptamine receptor 4 Mus musculus 524.8 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82087 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82087&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search F5U 7BS4,7WB8,7BRX,7DAK 1833 131342661 C05659 ZINC00057163 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172434 COc1ccc2[nH]cc(CCN)c2c1 InChI=1S/C11H14N2O/c1-14-9-2-3-11-10(6-9)8(4-5-12)7-13-11/h2-3,6-7,13H,4-5,12H2,1H3 JTEJPPKMYBDEMY-UHFFFAOYSA-N 82087 2-(5-methoxy-1H-indol-3-yl)ethanamine::5-MT::5-Methoxytryptamine hydrochloride::CAS_66-83-1::tryptamine, 5-Methoxy 5-hydroxytryptamine receptor 4 Mus musculus 524.8 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82087 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82087&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search F5U 7BS4,7WB8,7BRX,7DAK 1833 131342661 C05659 ZINC00057163 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172436 CCn1c2ccccc2n(C(=O)NC2CC3CCC(C2)N3C)c1=O InChI=1S/C18H24N4O2/c1-3-21-15-6-4-5-7-16(15)22(18(21)24)17(23)19-12-10-13-8-9-14(11-12)20(13)2/h4-7,12-14H,3,8-11H2,1-2H3,(H,19,23) MZRKHUUDDHJVHS-UHFFFAOYSA-N 50007872 3-Ethyl-2-oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide; hydrochloride::BIMU 1::CHEMBL544755::CHEMBL62023 5-hydroxytryptamine receptor 4 Mus musculus 53.7 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007872&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 130946 103921140 CHEMBL544755CHEMBL62023 ZINC00004620 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172437 CCn1c2ccccc2n(C(=O)NC2CC3CCC(C2)N3C)c1=O InChI=1S/C18H24N4O2/c1-3-21-15-6-4-5-7-16(15)22(18(21)24)17(23)19-12-10-13-8-9-14(11-12)20(13)2/h4-7,12-14H,3,8-11H2,1-2H3,(H,19,23) MZRKHUUDDHJVHS-UHFFFAOYSA-N 50007872 3-Ethyl-2-oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide; hydrochloride::BIMU 1::CHEMBL544755::CHEMBL62023 5-hydroxytryptamine receptor 4 Mus musculus 53.7 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007872&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 130946 103921140 CHEMBL544755CHEMBL62023 ZINC00004620 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172440 CC(C)n1c2ccccc2n(C(=O)NC2C[C@@H]3CC[C@H](C2)N3C)c1=O InChI=1S/C19H26N4O2/c1-12(2)22-16-6-4-5-7-17(16)23(19(22)25)18(24)20-13-10-14-8-9-15(11-13)21(14)3/h4-7,12-15H,8-11H2,1-3H3,(H,20,24)/t13?,14-,15+ AFOFVIBWSLOHFR-GOOCMWNKSA-N 84648 BIMU 8 5-hydroxytryptamine receptor 4 Mus musculus 25.11 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84648 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84648&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5311029 136350748 ZINC00014556 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172441 CC(C)n1c2ccccc2n(C(=O)NC2C[C@@H]3CC[C@H](C2)N3C)c1=O InChI=1S/C19H26N4O2/c1-12(2)22-16-6-4-5-7-17(16)23(19(22)25)18(24)20-13-10-14-8-9-15(11-13)21(14)3/h4-7,12-15H,8-11H2,1-3H3,(H,20,24)/t13?,14-,15+ AFOFVIBWSLOHFR-GOOCMWNKSA-N 84648 BIMU 8 5-hydroxytryptamine receptor 4 Mus musculus 25.11 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84648 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84648&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5311029 136350748 ZINC00014556 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172444 COC1CN(CCCOc2ccc(F)cc2)CCC1NC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C23H29ClFN3O4/c1-30-21-13-19(26)18(24)12-17(21)23(29)27-20-8-10-28(14-22(20)31-2)9-3-11-32-16-6-4-15(25)5-7-16/h4-7,12-13,20,22H,3,8-11,14,26H2,1-2H3,(H,27,29) DCSUBABJRXZOMT-UHFFFAOYSA-N 50005836 4-Amino-5-chloro-N-{1-[3-(4-fluoro-phenoxy)-propyl]-3-methoxy-piperidin-4-yl}-2-methoxy-benzamide::4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-3-methoxypiperidin-4-yl)-2-methoxybenzamide::CHEMBL560739::CISAPRIDE::PROPULSID::US10167299, Cisapride::US10800776, Example Cisapride::US9221790, Cisapride::cid_5311047 5-hydroxytryptamine receptor 4 Mus musculus 51.28 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005836&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2769 103919261 CHEMBL560739 240 C06910 ZINC03830564 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172445 COC1CN(CCCOc2ccc(F)cc2)CCC1NC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C23H29ClFN3O4/c1-30-21-13-19(26)18(24)12-17(21)23(29)27-20-8-10-28(14-22(20)31-2)9-3-11-32-16-6-4-15(25)5-7-16/h4-7,12-13,20,22H,3,8-11,14,26H2,1-2H3,(H,27,29) DCSUBABJRXZOMT-UHFFFAOYSA-N 50005836 4-Amino-5-chloro-N-{1-[3-(4-fluoro-phenoxy)-propyl]-3-methoxy-piperidin-4-yl}-2-methoxy-benzamide::4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-3-methoxypiperidin-4-yl)-2-methoxybenzamide::CHEMBL560739::CISAPRIDE::PROPULSID::US10167299, Cisapride::US10800776, Example Cisapride::US9221790, Cisapride::cid_5311047 5-hydroxytryptamine receptor 4 Mus musculus 51.28 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005836&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2769 103919261 CHEMBL560739 240 C06910 ZINC03830564 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172447 COc1cc(N)c(Cl)cc1C(=O)NC1CCN(Cc2ccccc2)CC1 InChI=1S/C20H24ClN3O2/c1-26-19-12-18(22)17(21)11-16(19)20(25)23-15-7-9-24(10-8-15)13-14-5-3-2-4-6-14/h2-6,11-12,15H,7-10,13,22H2,1H3,(H,23,25) BVPWJMCABCPUQY-UHFFFAOYSA-N 50132693 4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-methoxy-benzamide(Clebopride)::4-amino-N-(1-benzylpiperidin-4-yl)-5-chloro-2-methoxybenzamide::CHEMBL325109::Clebopride 5-hydroxytryptamine receptor 4 Mus musculus 53.7 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132693&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2780 104023670 CHEMBL325109 ZINC00608261 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172448 CN1C2CCC1CC(C2)NC(=O)n1c2ccccc2[nH]c1=O InChI=1S/C16H20N4O2/c1-19-11-6-7-12(19)9-10(8-11)17-15(21)20-14-5-3-2-4-13(14)18-16(20)22/h2-5,10-12H,6-9H2,1H3,(H,17,21)(H,18,22) RWXRJSRJIITQAK-UHFFFAOYSA-N 50007892 2-Oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide; hydrochloride::CHEMBL539261::DAU 6215 5-hydroxytryptamine receptor 4 Mus musculus 223.87 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007892 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007892&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 60761 103921160 CHEMBL539261 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172450 COc1ccc2[nH]c(=O)n(C(=O)OC3CC4CCC(C3)N4C)c2c1 InChI=1S/C17H21N3O4/c1-19-10-3-4-11(19)8-13(7-10)24-17(22)20-15-9-12(23-2)5-6-14(15)18-16(20)21/h5-6,9-11,13H,3-4,7-8H2,1-2H3,(H,18,21) HKBNGEJJECJLOW-UHFFFAOYSA-N 50007863 6-Methoxy-2-oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester; hydrochloride::CHEMBL552854::DAU 6285 5-hydroxytryptamine receptor 4 Mus musculus 26.91 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007863&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 129928 103921131 CHEMBL552854 C02089 ZINC00005122 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172451 COc1ccc2[nH]c(=O)n(C(=O)OC3CC4CCC(C3)N4C)c2c1 InChI=1S/C17H21N3O4/c1-19-10-3-4-11(19)8-13(7-10)24-17(22)20-15-9-12(23-2)5-6-14(15)18-16(20)21/h5-6,9-11,13H,3-4,7-8H2,1-2H3,(H,18,21) HKBNGEJJECJLOW-UHFFFAOYSA-N 50007863 6-Methoxy-2-oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester; hydrochloride::CHEMBL552854::DAU 6285 5-hydroxytryptamine receptor 4 Mus musculus 26.91 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007863&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 129928 103921131 CHEMBL552854 C02089 ZINC00005122 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172453 Cn1cc(C(=O)OCC2CCN(CCNS(C)(=O)=O)CC2)c2ccccc12 InChI=1S/C19H27N3O4S/c1-21-13-17(16-5-3-4-6-18(16)21)19(23)26-14-15-7-10-22(11-8-15)12-9-20-27(2,24)25/h3-6,13,15,20H,7-12,14H2,1-2H3 MOZPSIXKYJUTKI-UHFFFAOYSA-N 29525 3H-GR113808::CHEMBL518682::GR 113808::[3H] GR 113808::[3H]GR113808 5-hydroxytryptamine receptor 4 Mus musculus 0.31 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29525 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29525&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 119376 81054954 73380 CHEMBL518682 259 ZINC00598220 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172454 Cn1cc(C(=O)OCC2CCN(CCNS(C)(=O)=O)CC2)c2ccccc12 InChI=1S/C19H27N3O4S/c1-21-13-17(16-5-3-4-6-18(16)21)19(23)26-14-15-7-10-22(11-8-15)12-9-20-27(2,24)25/h3-6,13,15,20H,7-12,14H2,1-2H3 MOZPSIXKYJUTKI-UHFFFAOYSA-N 29525 3H-GR113808::CHEMBL518682::GR 113808::[3H] GR 113808::[3H]GR113808 5-hydroxytryptamine receptor 4 Mus musculus 0.31 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29525 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29525&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 119376 81054954 73380 CHEMBL518682 259 ZINC00598220 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172456 COc1[nH]c2ccc(F)cc2c1C(=O)OCC1CCN(CCN[S](C)(=O)=O)CC1 InChI=1S/C19H26FN3O5S/c1-27-18-17(15-11-14(20)3-4-16(15)22-18)19(24)28-12-13-5-8-23(9-6-13)10-7-21-29(2,25)26/h3-4,11,13,21-22H,5-10,12H2,1-2H3 SSPCCAYAIDNNJX-UHFFFAOYSA-N 85020 5-Fluoro-2-methoxy-1H-indole-3-carboxylic acid [1-[2-[(methylsulfonyl)amino]ethyl]piperidin-4-yl]methyl ester::GR 125487::GR-125487 5-hydroxytryptamine receptor 4 Mus musculus 0.03 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85020&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 4284721 136351120 ZINC00598219 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172458 CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 InChI=1S/C17H20N2O2/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16/h2-5,10-13,18H,6-9H2,1H3 ZNRGQMMCGHDTEI-UHFFFAOYSA-N 50007871 CHEMBL8197::ICS 205-930::TROPISETRON 5-hydroxytryptamine receptor 4 Mus musculus 158.48 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007871&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search TKT 6HIS,2WNC,5OAJ 5595 103921139 CHEMBL8197 C02089 ZINC18130447 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172459 CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 InChI=1S/C17H20N2O2/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16/h2-5,10-13,18H,6-9H2,1H3 ZNRGQMMCGHDTEI-UHFFFAOYSA-N 50007871 CHEMBL8197::ICS 205-930::TROPISETRON 5-hydroxytryptamine receptor 4 Mus musculus 158.48 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007871&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search TKT 6HIS,2WNC,5OAJ 5595 103921139 CHEMBL8197 C02089 ZINC18130447 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172461 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19) TTWJBBZEZQICBI-UHFFFAOYSA-N 48320 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide;hydrochloride::4-azanyl-5-chloranyl-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::METOCLOPRAMIDE::METOCLOPRAMIDE HYDROCHLORIDE::MLS000069667::Metochloropramide::SMR000058471::US11147820, Compound Metoclopramide::US9132134, Metoclopramide::cid_23659 5-hydroxytryptamine receptor 4 Mus musculus 3981.07 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48320&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 4168 252628615 DB01233 C07868 ZINC01530716 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172463 COc1cc(N)c(Cl)cc1C(=O)NC1CCN2CCCC1C2 InChI=1S/C16H22ClN3O2/c1-22-15-8-13(18)12(17)7-11(15)16(21)19-14-4-6-20-5-2-3-10(14)9-20/h7-8,10,14H,2-6,9,18H2,1H3,(H,19,21) GZSKEXSLDPEFPT-UHFFFAOYSA-N 82422 CAS_109872-41-5::NSC_3035240::RENZAPRIDE 5-hydroxytryptamine receptor 4 Mus musculus 97.72 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82422&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3035241 136350393 ZINC13589966 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172464 COc1cc(N)c(Cl)cc1C(=O)NC1CCN2CCCC1C2 InChI=1S/C16H22ClN3O2/c1-22-15-8-13(18)12(17)7-11(15)16(21)19-14-4-6-20-5-2-3-10(14)9-20/h7-8,10,14H,2-6,9,18H2,1H3,(H,19,21) GZSKEXSLDPEFPT-UHFFFAOYSA-N 82422 CAS_109872-41-5::NSC_3035240::RENZAPRIDE 5-hydroxytryptamine receptor 4 Mus musculus 97.72 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82422&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3035241 136350393 ZINC13589966 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172466 COC1CN(CCCC(=O)N2CCC(CC2)N(C)C)CCC1NC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C25H40ClN5O4/c1-29(2)17-7-12-31(13-8-17)24(32)6-5-10-30-11-9-21(23(16-30)35-4)28-25(33)18-14-19(26)20(27)15-22(18)34-3/h14-15,17,21,23H,5-13,16,27H2,1-4H3,(H,28,33) YEXQFGBCXUNVRL-UHFFFAOYSA-N 85019 4-Amino-5-chloro-N-(1-{4-[4-(dimethylamino)-1-piperidinyl]-4-oxobutyl}-3-methoxy-4-piperidinyl)-2-methoxybenzamide::RN 76186 5-hydroxytryptamine receptor 4 Mus musculus 1.38 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85019&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 9936120 136351119 ZINC34039050 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172467 COc1ccc2[nH]cc(C3=CCCNC3)c2c1 InChI=1S/C14H16N2O/c1-17-11-4-5-14-12(7-11)13(9-16-14)10-3-2-6-15-8-10/h3-5,7,9,15-16H,2,6,8H2,1H3 WBJMGSVSSCEGFV-UHFFFAOYSA-N 50286073 5-Methoxy-3-(1,2,5,6-tetrahydro-pyridin-3-yl)-1H-indole::CHEMBL101487::RU 28253::RU-28253 5-hydroxytryptamine receptor 4 Mus musculus 602.55 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286073&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 10220205 104127644 CHEMBL101487 ZINC26744357 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172468 CCCC[N+]12CCC(C1)C(CC2)NC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C19H28ClN3O2/c1-3-4-7-23-8-5-13(12-23)17(6-9-23)22-19(24)14-10-15(20)16(21)11-18(14)25-2/h10-11,13,17H,3-9,12H2,1-2H3,(H2-,21,22,24)/p+1 ZGRCJMHVLTUIQH-UHFFFAOYSA-O 85018 SB205149 5-hydroxytryptamine receptor 4 Mus musculus 37.15 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85018&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 57339962 136351118 ZINC89455961 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172469 COc1cc(N)c(Cl)cc1C(=O)NC[C@@H]1CCN2CCC[C@@H]12 InChI=1S/C16H22ClN3O2/c1-22-15-8-13(18)12(17)7-11(15)16(21)19-9-10-4-6-20-5-2-3-14(10)20/h7-8,10,14H,2-6,9,18H2,1H3,(H,19,21)/t10-,14-/m0/s1 GAYSOZKZPOVDSB-HZMBPMFUSA-N 50005833 (exo)4-Amino-5-chloro-N-(hexahydro-pyrrolizin-1-ylmethyl)-2-methoxy-benzamide::4-Amino-5-chloro-2-methoxy-N-(7a-methyl-hexahydro-pyrrolizin-1-ylmethyl)-benzamide::4-Amino-5-chloro-N-(hexahydro-pyrrolizin-2-ylmethyl)-2-methoxy-benzamide::4-Amino-5-chloro-N-[(1S,7aS)-1-(hexahydro-pyrrolizin-1-yl)methyl]-2-methoxy-benzamide::4-amino-5-chloro-N-[(1S-cis-hexahydro-1H-pyrrolizin-1-yl)-methyl]-2-methoxybenzenecarboxamide::CHEMBL34291::SC-53116::SC49518::SC53116 5-hydroxytryptamine receptor 4 Mus musculus 50.11 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005833&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 132337 103919258 CHEMBL34291 238 ZINC03790774 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172470 COc1cc(N)c(Cl)cc1C(=O)NC[C@@H]1CCN2CCC[C@@H]12 InChI=1S/C16H22ClN3O2/c1-22-15-8-13(18)12(17)7-11(15)16(21)19-9-10-4-6-20-5-2-3-14(10)20/h7-8,10,14H,2-6,9,18H2,1H3,(H,19,21)/t10-,14-/m0/s1 GAYSOZKZPOVDSB-HZMBPMFUSA-N 50005833 (exo)4-Amino-5-chloro-N-(hexahydro-pyrrolizin-1-ylmethyl)-2-methoxy-benzamide::4-Amino-5-chloro-2-methoxy-N-(7a-methyl-hexahydro-pyrrolizin-1-ylmethyl)-benzamide::4-Amino-5-chloro-N-(hexahydro-pyrrolizin-2-ylmethyl)-2-methoxy-benzamide::4-Amino-5-chloro-N-[(1S,7aS)-1-(hexahydro-pyrrolizin-1-yl)methyl]-2-methoxy-benzamide::4-amino-5-chloro-N-[(1S-cis-hexahydro-1H-pyrrolizin-1-yl)-methyl]-2-methoxybenzenecarboxamide::CHEMBL34291::SC-53116::SC49518::SC53116 5-hydroxytryptamine receptor 4 Mus musculus 7.94 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005833&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 132337 103919258 CHEMBL34291 238 ZINC03790774 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172472 CCN(CC)CCOC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C14H21ClN2O3/c1-4-17(5-2)6-7-20-14(18)10-8-11(15)12(16)9-13(10)19-3/h8-9H,4-7,16H2,1-3H3 FFNWMBDISAYHDC-UHFFFAOYSA-N 50056401 2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]benzoate::4-Amino-5-chloro-2-methoxy-benzoic acid 2-diethylamino-ethyl ester::CHEMBL287045::SDZ 205557::SDZ-205557 5-hydroxytryptamine receptor 4 Mus musculus 6.3 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056401 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056401&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5191 103952673 CHEMBL287045 258 ZINC01544798 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172473 CCN(CC)CCOC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C14H21ClN2O3/c1-4-17(5-2)6-7-20-14(18)10-8-11(15)12(16)9-13(10)19-3/h8-9H,4-7,16H2,1-3H3 FFNWMBDISAYHDC-UHFFFAOYSA-N 50056401 2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]benzoate::4-Amino-5-chloro-2-methoxy-benzoic acid 2-diethylamino-ethyl ester::CHEMBL287045::SDZ 205557::SDZ-205557 5-hydroxytryptamine receptor 4 Mus musculus 6.3 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056401 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056401&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5191 103952673 CHEMBL287045 258 ZINC01544798 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172474 COc1cc(N)c(Cl)cc1C(=O)NC1CN2CCC1CC2 InChI=1S/C15H20ClN3O2/c1-21-14-7-12(17)11(16)6-10(14)15(20)18-13-8-19-4-2-9(13)3-5-19/h6-7,9,13H,2-5,8,17H2,1H3,(H,18,20) FEROPKNOYKURCJ-UHFFFAOYSA-N 50000492 (zacopride)4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide (Zacopride)::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide(zacopride)::CHEMBL18041::HTR5A4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::ZACOPRIDE::ZACOPRIDE,R::ZACOPRIDE,RS::ZACOPRIDE,S 5-hydroxytryptamine receptor 4 Mus musculus 1071.51 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000492 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000492&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 108182 103915040 CHEMBL18041 245 ZINC00003961 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172475 COc1cc(N)c(Cl)cc1C(=O)NC1CN2CCC1CC2 InChI=1S/C15H20ClN3O2/c1-21-14-7-12(17)11(16)6-10(14)15(20)18-13-8-19-4-2-9(13)3-5-19/h6-7,9,13H,2-5,8,17H2,1H3,(H,18,20) FEROPKNOYKURCJ-UHFFFAOYSA-N 50000492 (zacopride)4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide (Zacopride)::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide(zacopride)::CHEMBL18041::HTR5A4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::ZACOPRIDE::ZACOPRIDE,R::ZACOPRIDE,RS::ZACOPRIDE,S 5-hydroxytryptamine receptor 4 Mus musculus 301.99 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000492 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000492&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 108182 103915040 CHEMBL18041 245 ZINC00003961 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 172476 COc1cc(N)c(Cl)cc1C(=O)NC1CN2CCC1CC2 InChI=1S/C15H20ClN3O2/c1-21-14-7-12(17)11(16)6-10(14)15(20)18-13-8-19-4-2-9(13)3-5-19/h6-7,9,13H,2-5,8,17H2,1H3,(H,18,20) FEROPKNOYKURCJ-UHFFFAOYSA-N 50000492 (zacopride)4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide (Zacopride)::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide(zacopride)::CHEMBL18041::HTR5A4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::ZACOPRIDE::ZACOPRIDE,R::ZACOPRIDE,RS::ZACOPRIDE,S 5-hydroxytryptamine receptor 4 Mus musculus 223.87 PDSP Ki 10.1016/0014-2999(95)00786-5 10.7270/Q2GF0S1D 8867105 Ansanay, H; Sebben, M; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000492 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000492&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 108182 103915040 CHEMBL18041 245 ZINC00003961 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173298 NCCc1c[nH]c2ccc(cc12)C(N)=O InChI=1S/C11H13N3O/c12-4-3-8-6-14-10-2-1-7(11(13)15)5-9(8)10/h1-2,5-6,14H,3-4,12H2,(H2,13,15) WKZLNEWVIAGNAW-UHFFFAOYSA-N 21392 3-(2-aminoethyl)-1H-indole-5-carboxamide::5-CT::5-CT,DP::5-carboxamidotryptamine::CHEMBL1256863::CHEMBL18840::[3H]-5-CT::[3H]-5-Carboxamide tryptamine::[3H]-5-Carboxyamidotryptamine::[3H]-5-carboxamidotryptamine 5-hydroxytryptamine receptor 4 Mus musculus >10000 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21392 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21392&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 8K3 7X5H,7UM5,7XTC 1809 49689464 48292 CHEMBL1256863CHEMBL18840 4 ZINC02539813 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173299 NCCc1c[nH]c2ccc(cc12)C(N)=O InChI=1S/C11H13N3O/c12-4-3-8-6-14-10-2-1-7(11(13)15)5-9(8)10/h1-2,5-6,14H,3-4,12H2,(H2,13,15) WKZLNEWVIAGNAW-UHFFFAOYSA-N 21392 3-(2-aminoethyl)-1H-indole-5-carboxamide::5-CT::5-CT,DP::5-carboxamidotryptamine::CHEMBL1256863::CHEMBL18840::[3H]-5-CT::[3H]-5-Carboxamide tryptamine::[3H]-5-Carboxyamidotryptamine::[3H]-5-carboxamidotryptamine 5-hydroxytryptamine receptor 4 Mus musculus 9772.37 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21392 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21392&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 8K3 7X5H,7UM5,7XTC 1809 49689464 48292 CHEMBL1256863CHEMBL18840 4 ZINC02539813 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173300 NCCc1c[nH]c2ccc(O)cc12 InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 QZAYGJVTTNCVMB-UHFFFAOYSA-N 10755 14C-5-hydroxy tryptamine creatinine disulfate::2-imino-1-methylimidazolidin-4-one; 3-(2-aminoethyl)-1H-indol-5-ol; bis(sulfuric acid)::5-HT::5-Hydroxy Tryptamine::5-hydroxy tryptamine creatinine disulfate::CHEMBL535832::Serotonin::[3H]-5-HT 5-hydroxytryptamine receptor 4 Mus musculus 56.23 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10755&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search SRO 7WB7,7CFP,7BS9,3Q6K,3ADV,7YS6,6DG8,6DG7,7E2Y,7CFQ,2YMD,5MT3,5MT9,7TX8,7LI9,7LIA,6Y5A,7WC4,5MAM,6HIO,6HIN,6HIQ,7E32,3NK1,6KHN,2QEH,7BS2,3BRN,7MGW,4DUF,4DUE,7DAL,4DTW,7XTA,7XTB,7XT9,7XT8 5202 172097186 28790 CHEMBL535832 C00780 ZINC00057058 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173301 NCCc1c[nH]c2ccc(O)cc12 InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 QZAYGJVTTNCVMB-UHFFFAOYSA-N 10755 14C-5-hydroxy tryptamine creatinine disulfate::2-imino-1-methylimidazolidin-4-one; 3-(2-aminoethyl)-1H-indol-5-ol; bis(sulfuric acid)::5-HT::5-Hydroxy Tryptamine::5-hydroxy tryptamine creatinine disulfate::CHEMBL535832::Serotonin::[3H]-5-HT 5-hydroxytryptamine receptor 4 Mus musculus 79.43 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10755&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search SRO 7WB7,7CFP,7BS9,3Q6K,3ADV,7YS6,6DG8,6DG7,7E2Y,7CFQ,2YMD,5MT3,5MT9,7TX8,7LI9,7LIA,6Y5A,7WC4,5MAM,6HIO,6HIN,6HIQ,7E32,3NK1,6KHN,2QEH,7BS2,3BRN,7MGW,4DUF,4DUE,7DAL,4DTW,7XTA,7XTB,7XT9,7XT8 5202 172097186 28790 CHEMBL535832 C00780 ZINC00057058 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173302 COc1ccc2[nH]cc(CCN)c2c1 InChI=1S/C11H14N2O/c1-14-9-2-3-11-10(6-9)8(4-5-12)7-13-11/h2-3,6-7,13H,4-5,12H2,1H3 JTEJPPKMYBDEMY-UHFFFAOYSA-N 82087 2-(5-methoxy-1H-indol-3-yl)ethanamine::5-MT::5-Methoxytryptamine hydrochloride::CAS_66-83-1::tryptamine, 5-Methoxy 5-hydroxytryptamine receptor 4 Mus musculus 229.08 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82087 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82087&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search F5U 7BS4,7WB8,7BRX,7DAK 1833 131342661 C05659 ZINC00057163 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173303 COc1ccc2[nH]cc(CCN)c2c1 InChI=1S/C11H14N2O/c1-14-9-2-3-11-10(6-9)8(4-5-12)7-13-11/h2-3,6-7,13H,4-5,12H2,1H3 JTEJPPKMYBDEMY-UHFFFAOYSA-N 82087 2-(5-methoxy-1H-indol-3-yl)ethanamine::5-MT::5-Methoxytryptamine hydrochloride::CAS_66-83-1::tryptamine, 5-Methoxy 5-hydroxytryptamine receptor 4 Mus musculus 524.8 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82087 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82087&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search F5U 7BS4,7WB8,7BRX,7DAK 1833 131342661 C05659 ZINC00057163 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173304 CCn1c2ccccc2n(C(=O)NC2CC3CCC(C2)N3C)c1=O InChI=1S/C18H24N4O2/c1-3-21-15-6-4-5-7-16(15)22(18(21)24)17(23)19-12-10-13-8-9-14(11-12)20(13)2/h4-7,12-14H,3,8-11H2,1-2H3,(H,19,23) MZRKHUUDDHJVHS-UHFFFAOYSA-N 50007872 3-Ethyl-2-oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide; hydrochloride::BIMU 1::CHEMBL544755::CHEMBL62023 5-hydroxytryptamine receptor 4 Mus musculus 28.84 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007872&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 130946 103921140 CHEMBL544755CHEMBL62023 ZINC00004620 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173305 CCn1c2ccccc2n(C(=O)NC2CC3CCC(C2)N3C)c1=O InChI=1S/C18H24N4O2/c1-3-21-15-6-4-5-7-16(15)22(18(21)24)17(23)19-12-10-13-8-9-14(11-12)20(13)2/h4-7,12-14H,3,8-11H2,1-2H3,(H,19,23) MZRKHUUDDHJVHS-UHFFFAOYSA-N 50007872 3-Ethyl-2-oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide; hydrochloride::BIMU 1::CHEMBL544755::CHEMBL62023 5-hydroxytryptamine receptor 4 Mus musculus 53.7 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007872&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 130946 103921140 CHEMBL544755CHEMBL62023 ZINC00004620 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173306 CC(C)n1c2ccccc2n(C(=O)NC2C[C@@H]3CC[C@H](C2)N3C)c1=O InChI=1S/C19H26N4O2/c1-12(2)22-16-6-4-5-7-17(16)23(19(22)25)18(24)20-13-10-14-8-9-15(11-13)21(14)3/h4-7,12-15H,8-11H2,1-3H3,(H,20,24)/t13?,14-,15+ AFOFVIBWSLOHFR-GOOCMWNKSA-N 84648 BIMU 8 5-hydroxytryptamine receptor 4 Mus musculus 40.73 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84648 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84648&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5311029 136350748 ZINC00014556 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173307 CC(C)n1c2ccccc2n(C(=O)NC2C[C@@H]3CC[C@H](C2)N3C)c1=O InChI=1S/C19H26N4O2/c1-12(2)22-16-6-4-5-7-17(16)23(19(22)25)18(24)20-13-10-14-8-9-15(11-13)21(14)3/h4-7,12-15H,8-11H2,1-3H3,(H,20,24)/t13?,14-,15+ AFOFVIBWSLOHFR-GOOCMWNKSA-N 84648 BIMU 8 5-hydroxytryptamine receptor 4 Mus musculus 25.11 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84648 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84648&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5311029 136350748 ZINC00014556 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173308 COC1CN(CCCOc2ccc(F)cc2)CCC1NC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C23H29ClFN3O4/c1-30-21-13-19(26)18(24)12-17(21)23(29)27-20-8-10-28(14-22(20)31-2)9-3-11-32-16-6-4-15(25)5-7-16/h4-7,12-13,20,22H,3,8-11,14,26H2,1-2H3,(H,27,29) DCSUBABJRXZOMT-UHFFFAOYSA-N 50005836 4-Amino-5-chloro-N-{1-[3-(4-fluoro-phenoxy)-propyl]-3-methoxy-piperidin-4-yl}-2-methoxy-benzamide::4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-3-methoxypiperidin-4-yl)-2-methoxybenzamide::CHEMBL560739::CISAPRIDE::PROPULSID::US10167299, Cisapride::US10800776, Example Cisapride::US9221790, Cisapride::cid_5311047 5-hydroxytryptamine receptor 4 Mus musculus 32.35 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005836&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2769 103919261 CHEMBL560739 240 C06910 ZINC03830564 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173309 COC1CN(CCCOc2ccc(F)cc2)CCC1NC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C23H29ClFN3O4/c1-30-21-13-19(26)18(24)12-17(21)23(29)27-20-8-10-28(14-22(20)31-2)9-3-11-32-16-6-4-15(25)5-7-16/h4-7,12-13,20,22H,3,8-11,14,26H2,1-2H3,(H,27,29) DCSUBABJRXZOMT-UHFFFAOYSA-N 50005836 4-Amino-5-chloro-N-{1-[3-(4-fluoro-phenoxy)-propyl]-3-methoxy-piperidin-4-yl}-2-methoxy-benzamide::4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-3-methoxypiperidin-4-yl)-2-methoxybenzamide::CHEMBL560739::CISAPRIDE::PROPULSID::US10167299, Cisapride::US10800776, Example Cisapride::US9221790, Cisapride::cid_5311047 5-hydroxytryptamine receptor 4 Mus musculus 51.28 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005836&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 2769 103919261 CHEMBL560739 240 C06910 ZINC03830564 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173310 COc1ccc2[nH]c(=O)n(C(=O)OC3CC4CCC(C3)N4C)c2c1 InChI=1S/C17H21N3O4/c1-19-10-3-4-11(19)8-13(7-10)24-17(22)20-15-9-12(23-2)5-6-14(15)18-16(20)21/h5-6,9-11,13H,3-4,7-8H2,1-2H3,(H,18,21) HKBNGEJJECJLOW-UHFFFAOYSA-N 50007863 6-Methoxy-2-oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester; hydrochloride::CHEMBL552854::DAU 6285 5-hydroxytryptamine receptor 4 Mus musculus 54.95 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007863&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 129928 103921131 CHEMBL552854 C02089 ZINC00005122 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173311 COc1ccc2[nH]c(=O)n(C(=O)OC3CC4CCC(C3)N4C)c2c1 InChI=1S/C17H21N3O4/c1-19-10-3-4-11(19)8-13(7-10)24-17(22)20-15-9-12(23-2)5-6-14(15)18-16(20)21/h5-6,9-11,13H,3-4,7-8H2,1-2H3,(H,18,21) HKBNGEJJECJLOW-UHFFFAOYSA-N 50007863 6-Methoxy-2-oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester; hydrochloride::CHEMBL552854::DAU 6285 5-hydroxytryptamine receptor 4 Mus musculus 26.91 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007863&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 129928 103921131 CHEMBL552854 C02089 ZINC00005122 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173312 Cn1cc(C(=O)OCC2CCN(CCNS(C)(=O)=O)CC2)c2ccccc12 InChI=1S/C19H27N3O4S/c1-21-13-17(16-5-3-4-6-18(16)21)19(23)26-14-15-7-10-22(11-8-15)12-9-20-27(2,24)25/h3-6,13,15,20H,7-12,14H2,1-2H3 MOZPSIXKYJUTKI-UHFFFAOYSA-N 29525 3H-GR113808::CHEMBL518682::GR 113808::[3H] GR 113808::[3H]GR113808 5-hydroxytryptamine receptor 4 Mus musculus 0.2 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29525 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29525&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 119376 81054954 73380 CHEMBL518682 259 ZINC00598220 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173313 Cn1cc(C(=O)OCC2CCN(CCNS(C)(=O)=O)CC2)c2ccccc12 InChI=1S/C19H27N3O4S/c1-21-13-17(16-5-3-4-6-18(16)21)19(23)26-14-15-7-10-22(11-8-15)12-9-20-27(2,24)25/h3-6,13,15,20H,7-12,14H2,1-2H3 MOZPSIXKYJUTKI-UHFFFAOYSA-N 29525 3H-GR113808::CHEMBL518682::GR 113808::[3H] GR 113808::[3H]GR113808 5-hydroxytryptamine receptor 4 Mus musculus 0.31 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29525 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29525&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 119376 81054954 73380 CHEMBL518682 259 ZINC00598220 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173314 COc1[nH]c2ccc(F)cc2c1C(=O)OCC1CCN(CCN[S](C)(=O)=O)CC1 InChI=1S/C19H26FN3O5S/c1-27-18-17(15-11-14(20)3-4-16(15)22-18)19(24)28-12-13-5-8-23(9-6-13)10-7-21-29(2,25)26/h3-4,11,13,21-22H,5-10,12H2,1-2H3 SSPCCAYAIDNNJX-UHFFFAOYSA-N 85020 5-Fluoro-2-methoxy-1H-indole-3-carboxylic acid [1-[2-[(methylsulfonyl)amino]ethyl]piperidin-4-yl]methyl ester::GR 125487::GR-125487 5-hydroxytryptamine receptor 4 Mus musculus 0.02 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85020&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 4284721 136351120 ZINC00598219 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173315 COc1[nH]c2ccc(F)cc2c1C(=O)OCC1CCN(CCN[S](C)(=O)=O)CC1 InChI=1S/C19H26FN3O5S/c1-27-18-17(15-11-14(20)3-4-16(15)22-18)19(24)28-12-13-5-8-23(9-6-13)10-7-21-29(2,25)26/h3-4,11,13,21-22H,5-10,12H2,1-2H3 SSPCCAYAIDNNJX-UHFFFAOYSA-N 85020 5-Fluoro-2-methoxy-1H-indole-3-carboxylic acid [1-[2-[(methylsulfonyl)amino]ethyl]piperidin-4-yl]methyl ester::GR 125487::GR-125487 5-hydroxytryptamine receptor 4 Mus musculus 0.03 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85020&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 4284721 136351120 ZINC00598219 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173316 CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 InChI=1S/C17H20N2O2/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16/h2-5,10-13,18H,6-9H2,1H3 ZNRGQMMCGHDTEI-UHFFFAOYSA-N 50007871 CHEMBL8197::ICS 205-930::TROPISETRON 5-hydroxytryptamine receptor 4 Mus musculus 87.09 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007871&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search TKT 6HIS,2WNC,5OAJ 5595 103921139 CHEMBL8197 C02089 ZINC18130447 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173317 CN1C2CCC1CC(C2)OC(=O)c1c[nH]c2ccccc12 InChI=1S/C17H20N2O2/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16/h2-5,10-13,18H,6-9H2,1H3 ZNRGQMMCGHDTEI-UHFFFAOYSA-N 50007871 CHEMBL8197::ICS 205-930::TROPISETRON 5-hydroxytryptamine receptor 4 Mus musculus 158.48 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007871&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search TKT 6HIS,2WNC,5OAJ 5595 103921139 CHEMBL8197 C02089 ZINC18130447 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173318 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19) TTWJBBZEZQICBI-UHFFFAOYSA-N 48320 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide;hydrochloride::4-azanyl-5-chloranyl-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::METOCLOPRAMIDE::METOCLOPRAMIDE HYDROCHLORIDE::MLS000069667::Metochloropramide::SMR000058471::US11147820, Compound Metoclopramide::US9132134, Metoclopramide::cid_23659 5-hydroxytryptamine receptor 4 Mus musculus 891.25 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48320&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 4168 252628615 DB01233 C07868 ZINC01530716 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173319 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19) TTWJBBZEZQICBI-UHFFFAOYSA-N 48320 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide;hydrochloride::4-azanyl-5-chloranyl-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::METOCLOPRAMIDE::METOCLOPRAMIDE HYDROCHLORIDE::MLS000069667::Metochloropramide::SMR000058471::US11147820, Compound Metoclopramide::US9132134, Metoclopramide::cid_23659 5-hydroxytryptamine receptor 4 Mus musculus 3981.07 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48320&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 4168 252628615 DB01233 C07868 ZINC01530716 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173320 COc1cc(N)c(Cl)cc1C(=O)NC1CCN2CCCC1C2 InChI=1S/C16H22ClN3O2/c1-22-15-8-13(18)12(17)7-11(15)16(21)19-14-4-6-20-5-2-3-10(14)9-20/h7-8,10,14H,2-6,9,18H2,1H3,(H,19,21) GZSKEXSLDPEFPT-UHFFFAOYSA-N 82422 CAS_109872-41-5::NSC_3035240::RENZAPRIDE 5-hydroxytryptamine receptor 4 Mus musculus 131.82 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82422&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3035241 136350393 ZINC13589966 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173321 COc1cc(N)c(Cl)cc1C(=O)NC1CCN2CCCC1C2 InChI=1S/C16H22ClN3O2/c1-22-15-8-13(18)12(17)7-11(15)16(21)19-14-4-6-20-5-2-3-10(14)9-20/h7-8,10,14H,2-6,9,18H2,1H3,(H,19,21) GZSKEXSLDPEFPT-UHFFFAOYSA-N 82422 CAS_109872-41-5::NSC_3035240::RENZAPRIDE 5-hydroxytryptamine receptor 4 Mus musculus 97.72 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82422&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 3035241 136350393 ZINC13589966 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173322 COC1CN(CCCC(=O)N2CCC(CC2)N(C)C)CCC1NC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C25H40ClN5O4/c1-29(2)17-7-12-31(13-8-17)24(32)6-5-10-30-11-9-21(23(16-30)35-4)28-25(33)18-14-19(26)20(27)15-22(18)34-3/h14-15,17,21,23H,5-13,16,27H2,1-4H3,(H,28,33) YEXQFGBCXUNVRL-UHFFFAOYSA-N 85019 4-Amino-5-chloro-N-(1-{4-[4-(dimethylamino)-1-piperidinyl]-4-oxobutyl}-3-methoxy-4-piperidinyl)-2-methoxybenzamide::RN 76186 5-hydroxytryptamine receptor 4 Mus musculus 2.88 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85019&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 9936120 136351119 ZINC34039050 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173323 COC1CN(CCCC(=O)N2CCC(CC2)N(C)C)CCC1NC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C25H40ClN5O4/c1-29(2)17-7-12-31(13-8-17)24(32)6-5-10-30-11-9-21(23(16-30)35-4)28-25(33)18-14-19(26)20(27)15-22(18)34-3/h14-15,17,21,23H,5-13,16,27H2,1-4H3,(H,28,33) YEXQFGBCXUNVRL-UHFFFAOYSA-N 85019 4-Amino-5-chloro-N-(1-{4-[4-(dimethylamino)-1-piperidinyl]-4-oxobutyl}-3-methoxy-4-piperidinyl)-2-methoxybenzamide::RN 76186 5-hydroxytryptamine receptor 4 Mus musculus 1.38 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85019&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 9936120 136351119 ZINC34039050 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173324 COc1cc(N)c(Cl)cc1C(=O)NC[C@@H]1CCN2CCC[C@@H]12 InChI=1S/C16H22ClN3O2/c1-22-15-8-13(18)12(17)7-11(15)16(21)19-9-10-4-6-20-5-2-3-14(10)20/h7-8,10,14H,2-6,9,18H2,1H3,(H,19,21)/t10-,14-/m0/s1 GAYSOZKZPOVDSB-HZMBPMFUSA-N 50005833 (exo)4-Amino-5-chloro-N-(hexahydro-pyrrolizin-1-ylmethyl)-2-methoxy-benzamide::4-Amino-5-chloro-2-methoxy-N-(7a-methyl-hexahydro-pyrrolizin-1-ylmethyl)-benzamide::4-Amino-5-chloro-N-(hexahydro-pyrrolizin-2-ylmethyl)-2-methoxy-benzamide::4-Amino-5-chloro-N-[(1S,7aS)-1-(hexahydro-pyrrolizin-1-yl)methyl]-2-methoxy-benzamide::4-amino-5-chloro-N-[(1S-cis-hexahydro-1H-pyrrolizin-1-yl)-methyl]-2-methoxybenzenecarboxamide::CHEMBL34291::SC-53116::SC49518::SC53116 5-hydroxytryptamine receptor 4 Mus musculus 7.41 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005833&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 132337 103919258 CHEMBL34291 238 ZINC03790774 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173325 COc1cc(N)c(Cl)cc1C(=O)NC[C@@H]1CCN2CCC[C@@H]12 InChI=1S/C16H22ClN3O2/c1-22-15-8-13(18)12(17)7-11(15)16(21)19-9-10-4-6-20-5-2-3-14(10)20/h7-8,10,14H,2-6,9,18H2,1H3,(H,19,21)/t10-,14-/m0/s1 GAYSOZKZPOVDSB-HZMBPMFUSA-N 50005833 (exo)4-Amino-5-chloro-N-(hexahydro-pyrrolizin-1-ylmethyl)-2-methoxy-benzamide::4-Amino-5-chloro-2-methoxy-N-(7a-methyl-hexahydro-pyrrolizin-1-ylmethyl)-benzamide::4-Amino-5-chloro-N-(hexahydro-pyrrolizin-2-ylmethyl)-2-methoxy-benzamide::4-Amino-5-chloro-N-[(1S,7aS)-1-(hexahydro-pyrrolizin-1-yl)methyl]-2-methoxy-benzamide::4-amino-5-chloro-N-[(1S-cis-hexahydro-1H-pyrrolizin-1-yl)-methyl]-2-methoxybenzenecarboxamide::CHEMBL34291::SC-53116::SC49518::SC53116 5-hydroxytryptamine receptor 4 Mus musculus 7.94 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005833&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 132337 103919258 CHEMBL34291 238 ZINC03790774 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173326 CCN(CC)CCOC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C14H21ClN2O3/c1-4-17(5-2)6-7-20-14(18)10-8-11(15)12(16)9-13(10)19-3/h8-9H,4-7,16H2,1-3H3 FFNWMBDISAYHDC-UHFFFAOYSA-N 50056401 2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]benzoate::4-Amino-5-chloro-2-methoxy-benzoic acid 2-diethylamino-ethyl ester::CHEMBL287045::SDZ 205557::SDZ-205557 5-hydroxytryptamine receptor 4 Mus musculus 7.76 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056401 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056401&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5191 103952673 CHEMBL287045 258 ZINC01544798 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173327 CCN(CC)CCOC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C14H21ClN2O3/c1-4-17(5-2)6-7-20-14(18)10-8-11(15)12(16)9-13(10)19-3/h8-9H,4-7,16H2,1-3H3 FFNWMBDISAYHDC-UHFFFAOYSA-N 50056401 2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]benzoate::4-Amino-5-chloro-2-methoxy-benzoic acid 2-diethylamino-ethyl ester::CHEMBL287045::SDZ 205557::SDZ-205557 5-hydroxytryptamine receptor 4 Mus musculus 6.3 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056401 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056401&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 5191 103952673 CHEMBL287045 258 ZINC01544798 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173328 COc1cc(N)c(Cl)cc1C(=O)NC1CN2CCC1CC2 InChI=1S/C15H20ClN3O2/c1-21-14-7-12(17)11(16)6-10(14)15(20)18-13-8-19-4-2-9(13)3-5-19/h6-7,9,13H,2-5,8,17H2,1H3,(H,18,20) FEROPKNOYKURCJ-UHFFFAOYSA-N 50000492 (zacopride)4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide (Zacopride)::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide(zacopride)::CHEMBL18041::HTR5A4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::ZACOPRIDE::ZACOPRIDE,R::ZACOPRIDE,RS::ZACOPRIDE,S 5-hydroxytryptamine receptor 4 Mus musculus 190.54 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000492 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000492&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 108182 103915040 CHEMBL18041 245 ZINC00003961 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 173329 COc1cc(N)c(Cl)cc1C(=O)NC1CN2CCC1CC2 InChI=1S/C15H20ClN3O2/c1-21-14-7-12(17)11(16)6-10(14)15(20)18-13-8-19-4-2-9(13)3-5-19/h6-7,9,13H,2-5,8,17H2,1H3,(H,18,20) FEROPKNOYKURCJ-UHFFFAOYSA-N 50000492 (zacopride)4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide (Zacopride)::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide(zacopride)::CHEMBL18041::HTR5A4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::ZACOPRIDE::ZACOPRIDE,R::ZACOPRIDE,RS::ZACOPRIDE,S 5-hydroxytryptamine receptor 4 Mus musculus 223.87 PDSP Ki 10.1016/s0014-5793(96)01132-5 10.7270/Q228065Q 8946946 Claeysen, S; Sebben, M; Journot, L; Bockaert, J; Dumuis, A CNRS UPR 9023 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000492 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000492&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 108182 103915040 CHEMBL18041 245 ZINC00003961 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 50222354 CCCN1CCC(COc2nc3ccccc3c3NCCCc23)CC1 InChI=1S/C21H29N3O/c1-2-12-24-13-9-16(10-14-24)15-25-21-18-7-5-11-22-20(18)17-6-3-4-8-19(17)23-21/h3-4,6,8,16,22H,2,5,7,9-15H2,1H3 UTMXFLLOSBJGIE-UHFFFAOYSA-N 50122716 5-(Piperidin-4-ylmethoxy)-9-propyl-1,2,3,4-tetrahydro-benzo[h][1,6]naphthyridine::CHEMBL35226 5-hydroxytryptamine receptor 4 Mus musculus 0.560000 ChEMBL 10.1021/jm020954v 10.7270/Q2J67G8P 12502367 Hinschberger, A; Butt, S; Lelong, V; Boulouard, M; Dumuis, A; Dauphin, F; Bureau, R; Pfeiffer, B; Renard, P; Rault, S Université de Caen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122716 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122716&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 9881053 104015356 CHEMBL35226 ZINC29233810 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 50817000 CC(C)n1c2ccccc2n(C(=O)NC2CC3CCCC(C2)N3C)c1=O InChI=1S/C20H28N4O2/c1-13(2)23-17-9-4-5-10-18(17)24(20(23)26)19(25)21-14-11-15-7-6-8-16(12-14)22(15)3/h4-5,9-10,13-16H,6-8,11-12H2,1-3H3,(H,21,25) AJHCSFKCWMDCCD-UHFFFAOYSA-N 50122873 3-Isopropyl-2-oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid (9-methyl-9-aza-bicyclo[3.3.1]non-3-yl)-amide::CHEMBL324057 5-hydroxytryptamine receptor 4 Mus musculus 72 ChEMBL 10.1021/jm020099f 10.7270/Q2T72J6J 12540230 Langlois, M; Fischmeister, R Paris-Sud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122873 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122873&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 44343153 104015491 CHEMBL324057 ZINC27083407 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4 50817008 CCn1c2ccccc2n(C(=O)NC2CC3CCCC(C2)N3C)c1=O InChI=1S/C19H26N4O2/c1-3-22-16-9-4-5-10-17(16)23(19(22)25)18(24)20-13-11-14-7-6-8-15(12-13)21(14)2/h4-5,9-10,13-15H,3,6-8,11-12H2,1-2H3,(H,20,24) UEYRRMVOMQCUML-UHFFFAOYSA-N 50122877 3-Ethyl-2-oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid (9-methyl-9-aza-bicyclo[3.3.1]non-3-yl)-amide::CHEMBL325603 5-hydroxytryptamine receptor 4 Mus musculus 360 ChEMBL 10.1021/jm020099f 10.7270/Q2T72J6J 12540230 Langlois, M; Fischmeister, R Paris-Sud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122877 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000086&target=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122877&enzyme=5-hydroxytryptamine+receptor+4&column=ki&startPg=0&Increment=50&submit=Search 19426720 104015495 CHEMBL325603 ZINC27085311 1 MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPSDT 5-hydroxytryptamine receptor 4 5HT4R_MOUSE P97288 O89003 O89004 Q3URB5 Q9R2A4