BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 399461 CN[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N1[C@H](CNC(=O)c2ccccc2)Cc2cccnc12 InChI=1S/C24H31N5O3/c1-15(2)20(28-22(30)16(3)25-4)24(32)29-19(13-18-11-8-12-26-21(18)29)14-27-23(31)17-9-6-5-7-10-17/h5-12,15-16,19-20,25H,13-14H2,1-4H3,(H,27,31)(H,28,30)/t16-,19-,20-/m0/s1 RJWKBXICIIIARA-VDGAXYAQSA-N 228590 US9340573, 1 E3 ubiquitin-protein ligase XIAP [241-356] 52.98 7.5 37.00 C US Patent 10.7270/Q2FJ2FNT aid1802818 US9340573 Hogg, JH; Lou, Y Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228590 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9786&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228590&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search 76902766 336948112 1 MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTEGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT E3 ubiquitin-protein ligase XIAP XIAP_HUMAN P98170 D3DTF2 Q9NQ14 399462 CN[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N1[C@H](CNC(C)=O)Cc2cccnc12 InChI=1S/C19H29N5O3/c1-11(2)16(23-18(26)12(3)20-5)19(27)24-15(10-22-13(4)25)9-14-7-6-8-21-17(14)24/h6-8,11-12,15-16,20H,9-10H2,1-5H3,(H,22,25)(H,23,26)/t12-,15-,16-/m0/s1 SHSNGKZXZBGSLA-RCBQFDQVSA-N 228591 US9340573, 2 E3 ubiquitin-protein ligase XIAP [241-356] >54.8 7.5 37.00 C US Patent 10.7270/Q2FJ2FNT aid1802818 US9340573 Hogg, JH; Lou, Y Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228591 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9786&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228591&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search 117888130 336948113 1 MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTEGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT E3 ubiquitin-protein ligase XIAP XIAP_HUMAN P98170 D3DTF2 Q9NQ14 399463 CN[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N1[C@H](CNC(=O)NC)Cc2cccnc12 InChI=1S/C19H30N6O3/c1-11(2)15(24-17(26)12(3)20-4)18(27)25-14(10-23-19(28)21-5)9-13-7-6-8-22-16(13)25/h6-8,11-12,14-15,20H,9-10H2,1-5H3,(H,24,26)(H2,21,23,28)/t12-,14-,15-/m0/s1 DNDOKHQQWLFLBD-QEJZJMRPSA-N 228592 US9340573, 3 E3 ubiquitin-protein ligase XIAP [241-356] >54.8 7.5 37.00 C US Patent 10.7270/Q2FJ2FNT aid1802818 US9340573 Hogg, JH; Lou, Y Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228592 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9786&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228592&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search 117888137 336948114 1 MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTEGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT E3 ubiquitin-protein ligase XIAP XIAP_HUMAN P98170 D3DTF2 Q9NQ14 399464 CN[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N1[C@H](CNC(=O)Cc2ccccc2)Cc2cccnc12 InChI=1S/C25H33N5O3/c1-16(2)22(29-24(32)17(3)26-4)25(33)30-20(14-19-11-8-12-27-23(19)30)15-28-21(31)13-18-9-6-5-7-10-18/h5-12,16-17,20,22,26H,13-15H2,1-4H3,(H,28,31)(H,29,32)/t17-,20-,22-/m0/s1 XFVQREUYFZAMJL-XJABCFGWSA-N 228593 US9340573, 4 E3 ubiquitin-protein ligase XIAP [241-356] >54.8 7.5 37.00 C US Patent 10.7270/Q2FJ2FNT aid1802818 US9340573 Hogg, JH; Lou, Y Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9786&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228593&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search 73777099 336948115 1 MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTEGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT E3 ubiquitin-protein ligase XIAP XIAP_HUMAN P98170 D3DTF2 Q9NQ14 399465 CN[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N1[C@H](CNC(=O)OC)Cc2cccnc12 InChI=1S/C19H29N5O4/c1-11(2)15(23-17(25)12(3)20-4)18(26)24-14(10-22-19(27)28-5)9-13-7-6-8-21-16(13)24/h6-8,11-12,14-15,20H,9-10H2,1-5H3,(H,22,27)(H,23,25)/t12-,14-,15-/m0/s1 ZDWCGZXOBQMPMU-QEJZJMRPSA-N 228594 US9340573, 5 E3 ubiquitin-protein ligase XIAP [241-356] >54.8 7.5 37.00 C US Patent 10.7270/Q2FJ2FNT aid1802818 US9340573 Hogg, JH; Lou, Y Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9786&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228594&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search 73777124 336948116 1 MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTEGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT E3 ubiquitin-protein ligase XIAP XIAP_HUMAN P98170 D3DTF2 Q9NQ14 399466 CN[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N1[C@H](CNC(=O)N(C)C)Cc2cccnc12 InChI=1S/C20H32N6O3/c1-12(2)16(24-18(27)13(3)21-4)19(28)26-15(11-23-20(29)25(5)6)10-14-8-7-9-22-17(14)26/h7-9,12-13,15-16,21H,10-11H2,1-6H3,(H,23,29)(H,24,27)/t13-,15-,16-/m0/s1 WZRSIBRMVURXEQ-BPUTZDHNSA-N 228595 US9340573, 6 E3 ubiquitin-protein ligase XIAP [241-356] >54.8 7.5 37.00 C US Patent 10.7270/Q2FJ2FNT aid1802818 US9340573 Hogg, JH; Lou, Y Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228595 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9786&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228595&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search 73777101 336948117 1 MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTEGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT E3 ubiquitin-protein ligase XIAP XIAP_HUMAN P98170 D3DTF2 Q9NQ14 399467 CN[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N1[C@H](CNC(=O)Nc2ccccc2)Cc2cccnc12 InChI=1S/C24H32N6O3/c1-15(2)20(29-22(31)16(3)25-4)23(32)30-19(13-17-9-8-12-26-21(17)30)14-27-24(33)28-18-10-6-5-7-11-18/h5-12,15-16,19-20,25H,13-14H2,1-4H3,(H,29,31)(H2,27,28,33)/t16-,19-,20-/m0/s1 QTCYNUCDNBZLFI-VDGAXYAQSA-N 228596 US9340573, 7 E3 ubiquitin-protein ligase XIAP [241-356] >54.8 7.5 37.00 C US Patent 10.7270/Q2FJ2FNT aid1802818 US9340573 Hogg, JH; Lou, Y Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228596 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9786&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228596&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search 73777103 336948118 1 MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTEGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT E3 ubiquitin-protein ligase XIAP XIAP_HUMAN P98170 D3DTF2 Q9NQ14 399468 CN[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N1[C@H](CNC(=O)[C@@H](C)c2ccccc2)Cc2cccnc12 InChI=1S/C26H35N5O3/c1-16(2)22(30-25(33)18(4)27-5)26(34)31-21(14-20-12-9-13-28-23(20)31)15-29-24(32)17(3)19-10-7-6-8-11-19/h6-13,16-18,21-22,27H,14-15H2,1-5H3,(H,29,32)(H,30,33)/t17-,18-,21-,22-/m0/s1 HAXZTIUXLDHRTE-GPHNJDIKSA-N 228597 US9340573, 8 E3 ubiquitin-protein ligase XIAP [241-356] >54.8 7.5 37.00 C US Patent 10.7270/Q2FJ2FNT aid1802818 US9340573 Hogg, JH; Lou, Y Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228597 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9786&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228597&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search 127053762 336948119 1 MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTEGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT E3 ubiquitin-protein ligase XIAP XIAP_HUMAN P98170 D3DTF2 Q9NQ14 399469 CN[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N1[C@H](CNS(C)(=O)=O)Cc2cccnc12 InChI=1S/C18H29N5O4S/c1-11(2)15(22-17(24)12(3)19-4)18(25)23-14(10-21-28(5,26)27)9-13-7-6-8-20-16(13)23/h6-8,11-12,14-15,19,21H,9-10H2,1-5H3,(H,22,24)/t12-,14-,15-/m0/s1 AQPFZOROSFELID-QEJZJMRPSA-N 228598 US9340573, 9 E3 ubiquitin-protein ligase XIAP [241-356] >54.8 7.5 37.00 C US Patent 10.7270/Q2FJ2FNT aid1802818 US9340573 Hogg, JH; Lou, Y Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228598 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9786&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228598&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search 73777107 336948120 1 MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTEGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT E3 ubiquitin-protein ligase XIAP XIAP_HUMAN P98170 D3DTF2 Q9NQ14 399470 CN[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N1[C@H](CNS(=O)(=O)c2ccccc2)Cc2cccnc12 InChI=1S/C23H31N5O4S/c1-15(2)20(27-22(29)16(3)24-4)23(30)28-18(13-17-9-8-12-25-21(17)28)14-26-33(31,32)19-10-6-5-7-11-19/h5-12,15-16,18,20,24,26H,13-14H2,1-4H3,(H,27,29)/t16-,18-,20-/m0/s1 YEKKUTCQUXWIQW-QRFRQXIXSA-N 228599 US9340573, 10 E3 ubiquitin-protein ligase XIAP [241-356] >54.8 7.5 37.00 C US Patent 10.7270/Q2FJ2FNT aid1802818 US9340573 Hogg, JH; Lou, Y Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228599 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9786&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228599&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search 73777109 336948121 1 MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTEGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT E3 ubiquitin-protein ligase XIAP XIAP_HUMAN P98170 D3DTF2 Q9NQ14 399471 CN[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N1[C@H](CNC(=O)OCc2ccccc2)Cc2cccnc12 InChI=1S/C25H33N5O4/c1-16(2)21(29-23(31)17(3)26-4)24(32)30-20(13-19-11-8-12-27-22(19)30)14-28-25(33)34-15-18-9-6-5-7-10-18/h5-12,16-17,20-21,26H,13-15H2,1-4H3,(H,28,33)(H,29,31)/t17-,20-,21-/m0/s1 CRHVURUHLHTXLH-YYWHXJBOSA-N 228600 US9340573, 11 E3 ubiquitin-protein ligase XIAP [241-356] >54.8 7.5 37.00 C US Patent 10.7270/Q2FJ2FNT aid1802818 US9340573 Hogg, JH; Lou, Y Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228600 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9786&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228600&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search 117888639 336948122 1 MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTEGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT E3 ubiquitin-protein ligase XIAP XIAP_HUMAN P98170 D3DTF2 Q9NQ14 399472 CN[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N1[C@H](CNC(=O)Oc2ccccc2)Cc2cccnc12 InChI=1S/C24H31N5O4/c1-15(2)20(28-22(30)16(3)25-4)23(31)29-18(13-17-9-8-12-26-21(17)29)14-27-24(32)33-19-10-6-5-7-11-19/h5-12,15-16,18,20,25H,13-14H2,1-4H3,(H,27,32)(H,28,30)/t16-,18-,20-/m0/s1 YETRPNDFXWHVDD-QRFRQXIXSA-N 228601 US9340573, 12 E3 ubiquitin-protein ligase XIAP [241-356] >54.8 7.5 37.00 C US Patent 10.7270/Q2FJ2FNT aid1802818 US9340573 Hogg, JH; Lou, Y Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9786&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228601&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search 73777126 336948123 1 MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTEGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT E3 ubiquitin-protein ligase XIAP XIAP_HUMAN P98170 D3DTF2 Q9NQ14 399473 CN[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N1[C@H](CNc2ccccc2)Cc2cccnc12 InChI=1S/C23H31N5O2/c1-15(2)20(27-22(29)16(3)24-4)23(30)28-19(13-17-9-8-12-25-21(17)28)14-26-18-10-6-5-7-11-18/h5-12,15-16,19-20,24,26H,13-14H2,1-4H3,(H,27,29)/t16-,19-,20-/m0/s1 YLJJBQDWLZEISQ-VDGAXYAQSA-N 228602 US9340573, 13 E3 ubiquitin-protein ligase XIAP [241-356] 5.343 7.5 37.00 C US Patent 10.7270/Q2FJ2FNT aid1802818 US9340573 Hogg, JH; Lou, Y Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228602 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9786&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228602&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search 73443116 336948124 1 MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTEGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT E3 ubiquitin-protein ligase XIAP XIAP_HUMAN P98170 D3DTF2 Q9NQ14 399474 CN[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N1[C@H](CNc2ccc3ccccc3c2)Cc2cccnc12 InChI=1S/C27H33N5O2/c1-17(2)24(31-26(33)18(3)28-4)27(34)32-23(15-21-10-7-13-29-25(21)32)16-30-22-12-11-19-8-5-6-9-20(19)14-22/h5-14,17-18,23-24,28,30H,15-16H2,1-4H3,(H,31,33)/t18-,23-,24-/m0/s1 JYRTVNMQRJKWEK-NWVWQQAFSA-N 228603 US9340573, 14 E3 ubiquitin-protein ligase XIAP [241-356] 3.952 7.5 37.00 C US Patent 10.7270/Q2FJ2FNT aid1802818 US9340573 Hogg, JH; Lou, Y Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=228603 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9786&target=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=228603&enzyme=E3+ubiquitin-protein+ligase+XIAP+%5B241-356%5D&column=ki&startPg=0&Increment=50&submit=Search 73777128 336948125 1 MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTEGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTT E3 ubiquitin-protein ligase XIAP XIAP_HUMAN P98170 D3DTF2 Q9NQ14