BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 380915 CSCC[C@H](N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C24H39N5O12S/c1-11(2)19(23(39)28-15(24(40)41)10-18(34)35)29-22(38)14(5-7-17(32)33)27-21(37)13(4-6-16(30)31)26-20(36)12(25)8-9-42-3/h11-15,19H,4-10,25H2,1-3H3,(H,26,36)(H,27,37)(H,28,39)(H,29,38)(H,30,31)(H,32,33)(H,34,35)(H,40,41)/t12-,13-,14-,15-,19-/m0/s1 NANBGKDCGTYCAR-OXMIBSBGSA-N 217369 MEEVD Serine/threonine-protein phosphatase 5 1.4e+2 7.4 25.00 C Curated from the literature by BindingDB 10.1074/jbc.M113.519421 10.7270/Q2GH9GSN 24327656 aid1802484 Connarn, JN; Assimon, VA; Reed, RA; Tse, E; Southworth, DR; Zuiderweg, ER; Gestwicki, JE; Sun, D University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=217369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=217369&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 448228 329968978 C02715 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 1S95,1WAO,3H60,3H61,3H62,3H63,3H64,3H66,3H67,3H68,3H69,4JA7,4JA9,4ZVZ,4ZX2,5HPE,5UI1,5WG8,7ZR5,7ZR6 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 380916 CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C25H41N5O12/c1-5-12(4)19(26)23(39)28-13(6-8-16(31)32)21(37)27-14(7-9-17(33)34)22(38)30-20(11(2)3)24(40)29-15(25(41)42)10-18(35)36/h11-15,19-20H,5-10,26H2,1-4H3,(H,27,37)(H,28,39)(H,29,40)(H,30,38)(H,31,32)(H,33,34)(H,35,36)(H,41,42)/t12-,13-,14-,15-,19-,20-/m0/s1 OHKSATBFKOEABG-WUJJPXPXSA-N 217370 IEEVD Serine/threonine-protein phosphatase 5 426 7.4 25.00 C Curated from the literature by BindingDB 10.1074/jbc.M113.519421 10.7270/Q2GH9GSN 24327656 aid1802484 Connarn, JN; Assimon, VA; Reed, RA; Tse, E; Southworth, DR; Zuiderweg, ER; Gestwicki, JE; Sun, D University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=217370 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=217370&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 124221782 329968979 C02715 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 1S95,1WAO,3H60,3H61,3H62,3H63,3H64,3H66,3H67,3H68,3H69,4JA7,4JA9,4ZVZ,4ZX2,5HPE,5UI1,5WG8,7ZR5,7ZR6 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 380917 CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CO)NC(=O)[C@@H](N)CO)[C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C42H68N10O20/c1-6-19(4)32(50-41(70)33(20(5)55)51-38(67)26-8-7-13-52(26)27(56)15-44-35(64)25(17-54)48-34(63)21(43)16-53)40(69)46-22(9-11-28(57)58)36(65)45-23(10-12-29(59)60)37(66)49-31(18(2)3)39(68)47-24(42(71)72)14-30(61)62/h18-26,31-33,53-55H,6-17,43H2,1-5H3,(H,44,64)(H,45,65)(H,46,69)(H,47,68)(H,48,63)(H,49,66)(H,50,70)(H,51,67)(H,57,58)(H,59,60)(H,61,62)(H,71,72)/t19-,20+,21-,22-,23-,24-,25-,26-,31-,32-,33-/m0/s1 NIWUKZJGGPOXSC-ULXXIMJQSA-N 217373 SSGPTIEEVD Serine/threonine-protein phosphatase 5 1.06e+3 7.4 25.00 C Curated from the literature by BindingDB 10.1074/jbc.M113.519421 10.7270/Q2GH9GSN 24327656 aid1802484 Connarn, JN; Assimon, VA; Reed, RA; Tse, E; Southworth, DR; Zuiderweg, ER; Gestwicki, JE; Sun, D University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=217373 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=217373&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 124221785 329968982 C02715 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 1S95,1WAO,3H60,3H61,3H62,3H63,3H64,3H66,3H67,3H68,3H69,4JA7,4JA9,4ZVZ,4ZX2,5HPE,5UI1,5WG8,7ZR5,7ZR6 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 380918 CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CO)NC(=O)CN)[C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C41H66N10O19/c1-6-19(4)32(49-40(68)33(20(5)53)50-37(65)25-8-7-13-51(25)27(55)16-43-34(62)24(17-52)44-26(54)15-42)39(67)46-21(9-11-28(56)57)35(63)45-22(10-12-29(58)59)36(64)48-31(18(2)3)38(66)47-23(41(69)70)14-30(60)61/h18-25,31-33,52-53H,6-17,42H2,1-5H3,(H,43,62)(H,44,54)(H,45,63)(H,46,67)(H,47,66)(H,48,64)(H,49,68)(H,50,65)(H,56,57)(H,58,59)(H,60,61)(H,69,70)/t19-,20+,21-,22-,23-,24-,25-,31-,32-,33-/m0/s1 SSAWVKIVVWQSBR-NIAHAVLJSA-N 217374 GSGPTIEEVD Serine/threonine-protein phosphatase 5 1.55e+3 7.4 25.00 C Curated from the literature by BindingDB 10.1074/jbc.M113.519421 10.7270/Q2GH9GSN 24327656 aid1802484 Connarn, JN; Assimon, VA; Reed, RA; Tse, E; Southworth, DR; Zuiderweg, ER; Gestwicki, JE; Sun, D University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=217374 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=217374&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 124221786 329968983 C02715 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 1S95,1WAO,3H60,3H61,3H62,3H63,3H64,3H66,3H67,3H68,3H69,4JA7,4JA9,4ZVZ,4ZX2,5HPE,5UI1,5WG8,7ZR5,7ZR6 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 380919 CSCC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](N)CC(O)=O)[C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C45H73N13O23S/c1-18(2)33(42(78)55-26(44(80)81)16-32(69)70)57-39(75)23(8-10-29(63)64)52-37(73)22(7-9-28(61)62)51-38(74)24(11-13-82-4)53-36(72)21(6-5-12-49-45(47)48)50-41(77)27(17-59)56-43(79)34(19(3)60)58-40(76)25(15-31(67)68)54-35(71)20(46)14-30(65)66/h18-27,33-34,59-60H,5-17,46H2,1-4H3,(H,50,77)(H,51,74)(H,52,73)(H,53,72)(H,54,71)(H,55,78)(H,56,79)(H,57,75)(H,58,76)(H,61,62)(H,63,64)(H,65,66)(H,67,68)(H,69,70)(H,80,81)(H4,47,48,49)/t19-,20+,21+,22+,23+,24+,25+,26+,27+,33+,34+/m1/s1 XOLCOVVDQISNFH-LYLWIVQSSA-N 217371 DDTSRMEEVD Serine/threonine-protein phosphatase 5 79 7.4 25.00 C Curated from the literature by BindingDB 10.1074/jbc.M113.519421 10.7270/Q2GH9GSN 24327656 aid1802484 Connarn, JN; Assimon, VA; Reed, RA; Tse, E; Southworth, DR; Zuiderweg, ER; Gestwicki, JE; Sun, D University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=217371 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=217371&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 124221783 329968980 C02715 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 1S95,1WAO,3H60,3H61,3H62,3H63,3H64,3H66,3H67,3H68,3H69,4JA7,4JA9,4ZVZ,4ZX2,5HPE,5UI1,5WG8,7ZR5,7ZR6 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 380920 CSCC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](N)CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C45H73N13O22S/c1-19(2)34(43(78)56-27(44(79)80)17-33(68)69)58-40(75)24(9-12-31(64)65)53-38(73)23(8-11-30(62)63)52-39(74)25(13-15-81-4)54-37(72)22(6-5-14-49-45(47)48)51-42(77)28(18-59)57-35(70)20(3)50-41(76)26(16-32(66)67)55-36(71)21(46)7-10-29(60)61/h19-28,34,59H,5-18,46H2,1-4H3,(H,50,76)(H,51,77)(H,52,74)(H,53,73)(H,54,72)(H,55,71)(H,56,78)(H,57,70)(H,58,75)(H,60,61)(H,62,63)(H,64,65)(H,66,67)(H,68,69)(H,79,80)(H4,47,48,49)/t20-,21-,22-,23-,24-,25-,26-,27-,28-,34-/m0/s1 QCEGUAPHVOVOFM-HADJQBNFSA-N 217372 EDASRMEEVD Serine/threonine-protein phosphatase 5 77 7.4 25.00 C Curated from the literature by BindingDB 10.1074/jbc.M113.519421 10.7270/Q2GH9GSN 24327656 aid1802484 Connarn, JN; Assimon, VA; Reed, RA; Tse, E; Southworth, DR; Zuiderweg, ER; Gestwicki, JE; Sun, D University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=217372 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=217372&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 124221784 329968981 C02715 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 1S95,1WAO,3H60,3H61,3H62,3H63,3H64,3H66,3H67,3H68,3H69,4JA7,4JA9,4ZVZ,4ZX2,5HPE,5UI1,5WG8,7ZR5,7ZR6 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 380921 CSCC[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)CC(O)=O)C(C)C)C(O)=O InChI=1S/C24H39N5O12S/c1-11(2)19(29-20(36)12(25)10-18(34)35)23(39)27-14(5-7-17(32)33)21(37)26-13(4-6-16(30)31)22(38)28-15(24(40)41)8-9-42-3/h11-15,19H,4-10,25H2,1-3H3,(H,26,37)(H,27,39)(H,28,38)(H,29,36)(H,30,31)(H,32,33)(H,34,35)(H,40,41)/t12-,13-,14-,15-,19-/m0/s1 YSUBAPBUZBIUKW-OXMIBSBGSA-N 217375 DVEEM Serine/threonine-protein phosphatase 5 >1.0e+4 7.4 25.00 C Curated from the literature by BindingDB 10.1074/jbc.M113.519421 10.7270/Q2GH9GSN 24327656 aid1802484 Connarn, JN; Assimon, VA; Reed, RA; Tse, E; Southworth, DR; Zuiderweg, ER; Gestwicki, JE; Sun, D University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=217375 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=217375&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 124221787 329968984 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 1S95,1WAO,3H60,3H61,3H62,3H63,3H64,3H66,3H67,3H68,3H69,4JA7,4JA9,4ZVZ,4ZX2,5HPE,5UI1,5WG8,7ZR5,7ZR6 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 380922 CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CO)NC(=O)CN)[C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C40H64N10O19S/c1-18(2)31(38(66)47-23(40(68)69)14-30(59)60)48-36(64)21(8-10-29(57)58)45-34(62)20(7-9-28(55)56)44-35(63)22(11-13-70-4)46-39(67)32(19(3)52)49-37(65)25-6-5-12-50(25)27(54)16-42-33(61)24(17-51)43-26(53)15-41/h18-25,31-32,51-52H,5-17,41H2,1-4H3,(H,42,61)(H,43,53)(H,44,63)(H,45,62)(H,46,67)(H,47,66)(H,48,64)(H,49,65)(H,55,56)(H,57,58)(H,59,60)(H,68,69)/t19-,20+,21+,22+,23+,24+,25+,31+,32+/m1/s1 SPPARUSJHLYZPL-CWRASOKGSA-N 217377 GSGPTMEEVD Serine/threonine-protein phosphatase 5 133 7.4 25.00 C Curated from the literature by BindingDB 10.1074/jbc.M113.519421 10.7270/Q2GH9GSN 24327656 aid1802484 Connarn, JN; Assimon, VA; Reed, RA; Tse, E; Southworth, DR; Zuiderweg, ER; Gestwicki, JE; Sun, D University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=217377 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=217377&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 124221789 329968986 C02715 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 1S95,1WAO,3H60,3H61,3H62,3H63,3H64,3H66,3H67,3H68,3H69,4JA7,4JA9,4ZVZ,4ZX2,5HPE,5UI1,5WG8,7ZR5,7ZR6 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 380923 CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](N)CC(O)=O)[C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(O)=O InChI=1S/C46H75N13O23/c1-6-19(4)34(43(79)53-23(9-11-28(62)63)37(73)52-24(10-12-29(64)65)39(75)57-33(18(2)3)42(78)55-26(45(81)82)16-32(70)71)58-38(74)22(8-7-13-50-46(48)49)51-41(77)27(17-60)56-44(80)35(20(5)61)59-40(76)25(15-31(68)69)54-36(72)21(47)14-30(66)67/h18-27,33-35,60-61H,6-17,47H2,1-5H3,(H,51,77)(H,52,73)(H,53,79)(H,54,72)(H,55,78)(H,56,80)(H,57,75)(H,58,74)(H,59,76)(H,62,63)(H,64,65)(H,66,67)(H,68,69)(H,70,71)(H,81,82)(H4,48,49,50)/t19-,20+,21-,22-,23-,24-,25-,26-,27-,33-,34-,35-/m0/s1 BFKWHUCWUGCUPH-BZDRRIQDSA-N 217376 DDTSRIEEVD Serine/threonine-protein phosphatase 5 4.2e+2 7.4 25.00 C Curated from the literature by BindingDB 10.1074/jbc.M113.519421 10.7270/Q2GH9GSN 24327656 aid1802484 Connarn, JN; Assimon, VA; Reed, RA; Tse, E; Southworth, DR; Zuiderweg, ER; Gestwicki, JE; Sun, D University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=217376 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=217376&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 124221788 329968985 C02715 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 1S95,1WAO,3H60,3H61,3H62,3H63,3H64,3H66,3H67,3H68,3H69,4JA7,4JA9,4ZVZ,4ZX2,5HPE,5UI1,5WG8,7ZR5,7ZR6 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 50338257 CCCCC(Oc1cc(O)c(cc1C#Cc1ccccc1OC(F)(F)F)C(O)=O)C(=O)NC1CCCCC1 InChI=1S/C28H30F3NO6/c1-2-3-12-24(26(34)32-20-10-5-4-6-11-20)37-25-17-22(33)21(27(35)36)16-19(25)15-14-18-9-7-8-13-23(18)38-28(29,30)31/h7-9,13,16-17,20,24,33H,2-6,10-12H2,1H3,(H,32,34)(H,35,36) DPPSTFALTNIFPF-UHFFFAOYSA-N 50087856 CHEMBL3426913 Serine/threonine-protein phosphatase 5 >50000 7 ChEMBL 10.1016/j.bmc.2015.03.066 10.7270/Q2VD7168 25907364 He, Y; Guo, X; Yu, ZH; Wu, L; Gunawan, AM; Zhang, Y; Dixon, JE; Zhang, ZY Indiana University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087856 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087856&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 118737463 103986884 CHEMBL3426913 ZINC29471687 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 1S95,1WAO,3H60,3H61,3H62,3H63,3H64,3H66,3H67,3H68,3H69,4JA7,4JA9,4ZVZ,4ZX2,5HPE,5UI1,5WG8,7ZR5,7ZR6 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 50396609 OS(=O)(=O)C(C(=O)Nc1ccc(NC(=O)C(=O)Nc2ccc(I)cc2)cc1)c1ccccc1 InChI=1S/C22H18IN3O6S/c23-15-6-8-16(9-7-15)25-21(28)22(29)26-18-12-10-17(11-13-18)24-20(27)19(33(30,31)32)14-4-2-1-3-5-14/h1-13,19H,(H,24,27)(H,25,28)(H,26,29)(H,30,31,32) WYXKKFORWNIOFC-UHFFFAOYSA-N 50112356 CHEMBL3609373 Serine/threonine-protein phosphatase 5 >50000 ChEMBL 10.1021/acsmedchemlett.5b00118 10.7270/Q2251M0S 26191366 He, R; Yu, ZH; Zhang, RY; Wu, L; Gunawan, AM; Lane, BS; Shim, JS; Zeng, LF; He, Y; Chen, L; Wells, CD; Liu, JO; Zhang, ZY Indiana University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50112356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50112356&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 122187565 319493571 CHEMBL3609373 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 1S95,1WAO,3H60,3H61,3H62,3H63,3H64,3H66,3H67,3H68,3H69,4JA7,4JA9,4ZVZ,4ZX2,5HPE,5UI1,5WG8,7ZR5,7ZR6 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 50396610 NC(=O)c1cc[n+](CC2=C(N3[C@H](SC2)[C@H](NC(=O)C(c2ccccc2)S(O)(=O)=O)C3=O)C(O)=O)cc1 InChI=1S/C22H20N4O8S2/c23-18(27)13-6-8-25(9-7-13)10-14-11-35-21-15(20(29)26(21)16(14)22(30)31)24-19(28)17(36(32,33)34)12-4-2-1-3-5-12/h1-9,15,17,21H,10-11H2,(H4-,23,24,27,28,30,31,32,33,34)/p+1/t15-,17?,21-/m1/s1 SYLKGLMBLAAGSC-IKZMBGHXSA-O 50420258 CEFSULODIN Serine/threonine-protein phosphatase 5 >200000 ChEMBL 10.1021/acsmedchemlett.5b00118 10.7270/Q2251M0S 26191366 He, R; Yu, ZH; Zhang, RY; Wu, L; Gunawan, AM; Lane, BS; Shim, JS; Zeng, LF; He, Y; Chen, L; Wells, CD; Liu, JO; Zhang, ZY Indiana University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50420258 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50420258&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 40247 163369282 C00875 ZINC03830467 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 1S95,1WAO,3H60,3H61,3H62,3H63,3H64,3H66,3H67,3H68,3H69,4JA7,4JA9,4ZVZ,4ZX2,5HPE,5UI1,5WG8,7ZR5,7ZR6 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 50396615 CC(C)c1ccc(NC(=O)C(=O)Nc2ccc(NC(=O)C(c3ccccc3)S(O)(=O)=O)cc2)cc1 InChI=1S/C25H25N3O6S/c1-16(2)17-8-10-19(11-9-17)27-24(30)25(31)28-21-14-12-20(13-15-21)26-23(29)22(35(32,33)34)18-6-4-3-5-7-18/h3-16,22H,1-2H3,(H,26,29)(H,27,30)(H,28,31)(H,32,33,34) YIYXIVBATWWRQJ-UHFFFAOYSA-N 50112357 CHEMBL3609375 Serine/threonine-protein phosphatase 5 >50000 ChEMBL 10.1021/acsmedchemlett.5b00118 10.7270/Q2251M0S 26191366 He, R; Yu, ZH; Zhang, RY; Wu, L; Gunawan, AM; Lane, BS; Shim, JS; Zeng, LF; He, Y; Chen, L; Wells, CD; Liu, JO; Zhang, ZY Indiana University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50112357 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50112357&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 122187567 319493572 CHEMBL3609375 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 1S95,1WAO,3H60,3H61,3H62,3H63,3H64,3H66,3H67,3H68,3H69,4JA7,4JA9,4ZVZ,4ZX2,5HPE,5UI1,5WG8,7ZR5,7ZR6 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 50396616 OS(=O)(=O)C(C(=O)Nc1ccc(NC(=O)C(=O)Nc2ccc(cc2)-c2ccccc2)cc1)c1ccccc1 InChI=1S/C28H23N3O6S/c32-26(25(38(35,36)37)21-9-5-2-6-10-21)29-23-15-17-24(18-16-23)31-28(34)27(33)30-22-13-11-20(12-14-22)19-7-3-1-4-8-19/h1-18,25H,(H,29,32)(H,30,33)(H,31,34)(H,35,36,37) UNNZCNDZZKUQJC-UHFFFAOYSA-N 50112358 CHEMBL3609374 Serine/threonine-protein phosphatase 5 >50000 ChEMBL 10.1021/acsmedchemlett.5b00118 10.7270/Q2251M0S 26191366 He, R; Yu, ZH; Zhang, RY; Wu, L; Gunawan, AM; Lane, BS; Shim, JS; Zeng, LF; He, Y; Chen, L; Wells, CD; Liu, JO; Zhang, ZY Indiana University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50112358 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50112358&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 122187566 319493573 CHEMBL3609374 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 1S95,1WAO,3H60,3H61,3H62,3H63,3H64,3H66,3H67,3H68,3H69,4JA7,4JA9,4ZVZ,4ZX2,5HPE,5UI1,5WG8,7ZR5,7ZR6 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 51507014 Cc1c(Br)cc(NC(=O)CS(O)(=O)=O)cc1Br InChI=1S/C9H9Br2NO4S/c1-5-7(10)2-6(3-8(5)11)12-9(13)4-17(14,15)16/h2-3H,4H2,1H3,(H,12,13)(H,14,15,16) PGYFUNHIFMBZCB-UHFFFAOYSA-N 50607110 CHEMBL5219519 Serine/threonine-protein phosphatase 5 >100000 ChEMBL 10.7270/Q2BK1HGF 36197449 He, R; Wang, J; Yu, ZH; Moyers, JS; Michael, MD; Durham, TB; Cramer, JW; Qian, Y; Lin, A; Wu, L; Noinaj, N; Barrett, DG; Zhang, ZY Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50607110 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50607110&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 124115158 482617961 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 1S95,1WAO,3H60,3H61,3H62,3H63,3H64,3H66,3H67,3H68,3H69,4JA7,4JA9,4ZVZ,4ZX2,5HPE,5UI1,5WG8,7ZR5,7ZR6 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 51507015 Cc1c(Br)cc(NC(=O)NS(O)(=O)=O)cc1Br InChI=1S/C8H8Br2N2O4S/c1-4-6(9)2-5(3-7(4)10)11-8(13)12-17(14,15)16/h2-3H,1H3,(H2,11,12,13)(H,14,15,16) XBWKZLBEUSPLFY-UHFFFAOYSA-N 50607111 CHEMBL5218807 Serine/threonine-protein phosphatase 5 >10000 ChEMBL 10.7270/Q2BK1HGF 36197449 He, R; Wang, J; Yu, ZH; Moyers, JS; Michael, MD; Durham, TB; Cramer, JW; Qian, Y; Lin, A; Wu, L; Noinaj, N; Barrett, DG; Zhang, ZY Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50607111 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50607111&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 165413065 482617962 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 1S95,1WAO,3H60,3H61,3H62,3H63,3H64,3H66,3H67,3H68,3H69,4JA7,4JA9,4ZVZ,4ZX2,5HPE,5UI1,5WG8,7ZR5,7ZR6 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 51507016 Cc1c(Br)cc(NC(=O)C(c2ccccc2)S(O)(=O)=O)cc1Br InChI=1S/C15H13Br2NO4S/c1-9-12(16)7-11(8-13(9)17)18-15(19)14(23(20,21)22)10-5-3-2-4-6-10/h2-8,14H,1H3,(H,18,19)(H,20,21,22) DWUBYIFZVUOBSF-UHFFFAOYSA-N 50558488 CHEMBL4794972 Serine/threonine-protein phosphatase 5 >200000 ChEMBL 10.7270/Q2BK1HGF 36197449 He, R; Wang, J; Yu, ZH; Moyers, JS; Michael, MD; Durham, TB; Cramer, JW; Qian, Y; Lin, A; Wu, L; Noinaj, N; Barrett, DG; Zhang, ZY Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558488 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558488&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 124115152 461828880 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 1S95,1WAO,3H60,3H61,3H62,3H63,3H64,3H66,3H67,3H68,3H69,4JA7,4JA9,4ZVZ,4ZX2,5HPE,5UI1,5WG8,7ZR5,7ZR6 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 51015614 C[C@]12[C@@H]3CC[C@@H](O3)[C@@]1(C)C(=O)OC2=O InChI=1S/C10H12O4/c1-9-5-3-4-6(13-5)10(9,2)8(12)14-7(9)11/h5-6H,3-4H2,1-2H3/t5-,6+,9+,10- DHZBEENLJMYSHQ-XCVPVQRUSA-N 50090505 (1R,2S,6R,7S)-2,6-Dimethyl-4,10-dioxa-tricyclo[5.2.1.0*2,6*]decane-3,5-dione::(1R,7S)-2,6-Dimethyl-4,10-dioxa-tricyclo[5.2.1.0*2,6*]decane-3,5-dione::(1S,2R,6S,7R)-2,6-Dimethyl-4,10-dioxa-tricyclo[5.2.1.0*2,6*]decane-3,5-dione::(1S,3S,4R,7R)-2,6-dimethyl-4,10-dioxa-tricyclo[5.2.1.0-2,6]decane-3,5-dione::CANTHARIDIN::CHEMBL48449::cid_6708701 Serine/threonine-protein phosphatase 5 600 ChEMBL 10.7270/Q2WD44RV 34156850 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090505 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090505&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 5944 103988982 64213 CHEMBL48449 C16778 ZINC17611186 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 1S95,1WAO,3H60,3H61,3H62,3H63,3H64,3H66,3H67,3H68,3H69,4JA7,4JA9,4ZVZ,4ZX2,5HPE,5UI1,5WG8,7ZR5,7ZR6 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 51015748 CO[C@@H](Cc1ccccc1)[C@@H](C)\C=C(/C)\C=C\[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](C)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](C)NC(=O)C(=C)N(C)C(=O)CC[C@@H](NC(=O)[C@H]1C)C(O)=O)C(O)=O InChI=1S/C49H74N10O12/c1-26(2)23-37-46(66)58-40(48(69)70)30(6)42(62)55-35(17-14-22-52-49(50)51)45(65)54-34(19-18-27(3)24-28(4)38(71-10)25-33-15-12-11-13-16-33)29(5)41(61)56-36(47(67)68)20-21-39(60)59(9)32(8)44(64)53-31(7)43(63)57-37/h11-13,15-16,18-19,24,26,28-31,34-38,40H,8,14,17,20-23,25H2,1-7,9-10H3,(H,53,64)(H,54,65)(H,55,62)(H,56,61)(H,57,63)(H,58,66)(H,67,68)(H,69,70)(H4,50,51,52)/b19-18+,27-24+/t28-,29-,30-,31+,34-,35-,36+,37-,38-,40+/m0/s1 ZYZCGGRZINLQBL-GWRQVWKTSA-N 50061067 15-(3-Guanidino-propyl)-8-isobutyl-18-((1E,3E)-6-methoxy-3,5-dimethyl-7-phenyl-hepta-1,3-dienyl)-1,5,12,19-tetramethyl-2-methylene-3,6,9,13,16,20,25-heptaoxo-1,4,7,10,14,17,21heptaaza-cyclopentacosane-11,22-dicarboxylic acid::15-(3-Guanidino-propyl)-8-isobutyl-18-(6-methoxy-3,5-dimethyl-7-phenyl-hepta-1,3-dienyl)-1,5,12,19-tetramethyl-2-methylene-3,6,9,13,16,20,25-heptaoxo-1,4,7,10,14,17,21heptaaza-cyclopentacosane-11,22-dicarboxylic acid::8-[3-amino(imino)methylaminopropyl]-15-isobutyl-5-[6-methoxy-3,5-dimethyl-7-phenyl-(1E,3E)-1,3-heptadienyl]-4,11,18,22-tetramethyl-21-methylene-3,7,10,14,17,20,23-heptaoxo-2,6,9,13,16,19,22-heptaazacyclopentacosane-1,12-dicarboxylic acid::CHEMBL444092::Microcystin-LR Serine/threonine-protein phosphatase 5 1.000000 ChEMBL 10.7270/Q2WD44RV 34156850 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061067&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 445434 103956654 CHEMBL444092 C05371 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 1S95,1WAO,3H60,3H61,3H62,3H63,3H64,3H66,3H67,3H68,3H69,4JA7,4JA9,4ZVZ,4ZX2,5HPE,5UI1,5WG8,7ZR5,7ZR6 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 51015864 N[C@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCCCCCCCC(=O)N[C@@H](CO)C(=O)N1Cc2ccccc2C[C@@H]1C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(O)=O InChI=1S/C42H68N12O8/c43-29(15-10-20-49-41(44)45)36(57)52-30(16-11-21-50-42(46)47)37(58)48-19-9-3-1-2-4-18-35(56)51-31(25-55)38(59)53-24-28-14-6-5-12-26(28)22-33(53)39(60)54-32-17-8-7-13-27(32)23-34(54)40(61)62/h5-6,12,14,27,29-34,55H,1-4,7-11,13,15-25,43H2,(H,48,58)(H,51,56)(H,52,57)(H,61,62)(H4,44,45,49)(H4,46,47,50)/t27-,29+,30-,31-,32-,33+,34-/m0/s1 YCJVSBPCAZZFFP-YEQRNYPQSA-N 50408820 CHEMBL5268133 Serine/threonine-protein phosphatase 5 3.5 ChEMBL 10.7270/Q2WD44RV 34156850 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408820 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408820&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 44354214 163357844 CHEMBL335247 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 1S95,1WAO,3H60,3H61,3H62,3H63,3H64,3H66,3H67,3H68,3H69,4JA7,4JA9,4ZVZ,4ZX2,5HPE,5UI1,5WG8,7ZR5,7ZR6 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 51015865 CO[C@H]([C@H](O)CC(=O)[C@@H](C)[C@@H](O)CC[C@@H](C)[C@@H]1O[C@]2(CC[C@@H](C)[C@H](CC[C@H](C)C(C)=O)O2)CC[C@@H]1C)[C@H](OC(=O)C[C@@H](O)C1=C(C)C(=O)OC1=O)C(C)C InChI=1S/C41H66O13/c1-21(2)36(51-34(47)20-31(45)35-27(8)39(48)52-40(35)49)38(50-10)32(46)19-30(44)26(7)29(43)13-11-24(5)37-25(6)16-18-41(54-37)17-15-23(4)33(53-41)14-12-22(3)28(9)42/h21-26,29,31-33,36-38,43,45-46H,11-20H2,1-10H3/t22-,23+,24+,25-,26-,29-,31+,32+,33-,36+,37-,38+,41+/m0/s1 RFCWHQNNCOJYTR-IRCAEPKSSA-N 50366883 TAUTOMYCIN Serine/threonine-protein phosphatase 5 10.0 ChEMBL 10.7270/Q2WD44RV 34156850 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366883 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366883&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 440646 160845985 C05372 ZINC95615663 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 1S95,1WAO,3H60,3H61,3H62,3H63,3H64,3H66,3H67,3H68,3H69,4JA7,4JA9,4ZVZ,4ZX2,5HPE,5UI1,5WG8,7ZR5,7ZR6 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 51016917 C[C@]12[C@@H]3CC[C@@H](O3)[C@@]1(C)C(=O)OC2=O InChI=1S/C10H12O4/c1-9-5-3-4-6(13-5)10(9,2)8(12)14-7(9)11/h5-6H,3-4H2,1-2H3/t5-,6+,9+,10- DHZBEENLJMYSHQ-XCVPVQRUSA-N 50090505 (1R,2S,6R,7S)-2,6-Dimethyl-4,10-dioxa-tricyclo[5.2.1.0*2,6*]decane-3,5-dione::(1R,7S)-2,6-Dimethyl-4,10-dioxa-tricyclo[5.2.1.0*2,6*]decane-3,5-dione::(1S,2R,6S,7R)-2,6-Dimethyl-4,10-dioxa-tricyclo[5.2.1.0*2,6*]decane-3,5-dione::(1S,3S,4R,7R)-2,6-dimethyl-4,10-dioxa-tricyclo[5.2.1.0-2,6]decane-3,5-dione::CANTHARIDIN::CHEMBL48449::cid_6708701 Serine/threonine-protein phosphatase 5 400 ChEMBL 10.7270/Q2WD44RV 34156850 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090505 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090505&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 5944 103988982 64213 CHEMBL48449 C16778 ZINC17611186 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 1S95,1WAO,3H60,3H61,3H62,3H63,3H64,3H66,3H67,3H68,3H69,4JA7,4JA9,4ZVZ,4ZX2,5HPE,5UI1,5WG8,7ZR5,7ZR6 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 51016918 COC[C@@H]([C@H](O)[C@H](O)C(=O)NCC[C@H](C)c1nc(\C=C\C[C@@H]2O[C@]3(C[C@@H](O)[C@@H]2C)O[C@H]([C@H](C[C@H](O)[C@H](C)[C@H](O)[C@H](C)\C=C(/C)\C(\C)=C\C=C\C(\C)=C/C#N)OC)[C@H](OP(O)(O)=O)C3(C)C)co1)N(C)C InChI=1S/C50H81N4O15P/c1-29(20-22-51)16-14-17-30(2)32(4)24-33(5)42(57)35(7)38(55)25-41(65-13)45-46(69-70(61,62)63)49(8,9)50(68-45)26-39(56)34(6)40(67-50)19-15-18-36-27-66-48(53-36)31(3)21-23-52-47(60)44(59)43(58)37(28-64-12)54(10)11/h14-18,20,24,27,31,33-35,37-46,55-59H,19,21,23,25-26,28H2,1-13H3,(H,52,60)(H2,61,62,63)/b16-14+,18-15+,29-20-,30-17+,32-24+/t31-,33+,34-,35-,37-,38-,39+,40-,41-,42+,43-,44-,45+,46-,50+/m0/s1 FKAWLXNLHHIHLA-YCBIHMBMSA-N 50110681 CHEMBL430266::Calyculin-A Serine/threonine-protein phosphatase 5 3.0 ChEMBL 10.7270/Q2WD44RV 34156850 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50110681 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50110681&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 5311365 104005414 CHEMBL430266 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 1S95,1WAO,3H60,3H61,3H62,3H63,3H64,3H66,3H67,3H68,3H69,4JA7,4JA9,4ZVZ,4ZX2,5HPE,5UI1,5WG8,7ZR5,7ZR6 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 51016919 N[C@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCCCCCC(=O)N[C@@H](CO)C(=O)N1Cc2ccccc2C[C@@H]1C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(O)=O InChI=1S/C40H64N12O8/c41-27(13-8-18-47-39(42)43)34(55)50-28(14-9-19-48-40(44)45)35(56)46-17-7-1-2-16-33(54)49-29(23-53)36(57)51-22-26-12-4-3-10-24(26)20-31(51)37(58)52-30-15-6-5-11-25(30)21-32(52)38(59)60/h3-4,10,12,25,27-32,53H,1-2,5-9,11,13-23,41H2,(H,46,56)(H,49,54)(H,50,55)(H,59,60)(H4,42,43,47)(H4,44,45,48)/t25-,27+,28-,29-,30-,31+,32-/m0/s1 KDYVEGLQNMHZED-FUPLYUBQSA-N 50408822 CHEMBL5276260 Serine/threonine-protein phosphatase 5 4.0 ChEMBL 10.7270/Q2WD44RV 34156850 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408822&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 44354162 163357846 CHEMBL134135 ZINC95549292 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 1S95,1WAO,3H60,3H61,3H62,3H63,3H64,3H66,3H67,3H68,3H69,4JA7,4JA9,4ZVZ,4ZX2,5HPE,5UI1,5WG8,7ZR5,7ZR6 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 51016920 CN1C[C@H](COC(=O)C2CCCCCC2)C=C2[C@H]1Cc1c[nH]c3cccc2c13 InChI=1S/C24H30N2O2/c1-26-14-16(15-28-24(27)17-7-4-2-3-5-8-17)11-20-19-9-6-10-21-23(19)18(13-25-21)12-22(20)26/h6,9-11,13,16-17,22,25H,2-5,7-8,12,14-15H2,1H3/t16-,22-/m1/s1 MNIFRAQAGOWVLM-OPAMFIHVSA-N 50408823 CHEMBL5276593 Serine/threonine-protein phosphatase 5 12 ChEMBL 10.7270/Q2WD44RV 34156850 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408823 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408823&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 10785927 163357847 CHEMBL157648 ZINC13793947 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 1S95,1WAO,3H60,3H61,3H62,3H63,3H64,3H66,3H67,3H68,3H69,4JA7,4JA9,4ZVZ,4ZX2,5HPE,5UI1,5WG8,7ZR5,7ZR6 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 51016921 C[C@@](O)(\C=C\[C@H]1CC=CC(=O)O1)[C@@H](C[C@@H](O)\C=C/C=C\C=C\CO)OP(O)(O)=O InChI=1S/C19H27O9P/c1-19(23,12-11-16-9-7-10-18(22)27-16)17(28-29(24,25)26)14-15(21)8-5-3-2-4-6-13-20/h2-8,10-12,15-17,20-21,23H,9,13-14H2,1H3,(H2,24,25,26)/b3-2-,6-4+,8-5-,12-11+/t15-,16+,17+,19+/m0/s1 ZMQRJWIYMXZORG-DSWNLJKISA-N 50110690 CHEMBL17377::FOSTRIECIN::Phosphoric acid mono-{3,10-dihydroxy-1-[1-hydroxy-1-methyl-3-(6-oxo-3,6-dihydro-2H-pyran-2-yl)-allyl]-deca-4,6,8-trienyl} ester Serine/threonine-protein phosphatase 5 >1.000000 ChEMBL 10.7270/Q2WD44RV 34156850 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50110690 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50110690&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 6913994 104005422 CHEMBL17377 ZINC05707379 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 1S95,1WAO,3H60,3H61,3H62,3H63,3H64,3H66,3H67,3H68,3H69,4JA7,4JA9,4ZVZ,4ZX2,5HPE,5UI1,5WG8,7ZR5,7ZR6 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 51016923 CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- YZXBAPSDXZZRGB-DOFZRALJSA-N 22319 (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid::Arachidonic acid::Arachidonic acid (AA)::CHEMBL15594::[1-14C]Arachidonic acid Serine/threonine-protein phosphatase 5 7.8 ChEMBL 10.7270/Q2WD44RV 34156850 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22319 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22319&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search ACD 1VYG,5ECF,6MCZ,1ADL,3V99,3FG4,3OLT,6LX9,8GHD,5CSD,4ZGA,6OII,4QWT,4DE6,2LBV,1DIY,1CVU,3TZI,5J5L,6MD2,6OFY,8H0C,6NBN,3HS5,7WJ1,1GNJ,4B0N,5FB7,1U67 444899 49846134 15843 CHEMBL15594 C00219 ZINC04474696 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 1S95,1WAO,3H60,3H61,3H62,3H63,3H64,3H66,3H67,3H68,3H69,4JA7,4JA9,4ZVZ,4ZX2,5HPE,5UI1,5WG8,7ZR5,7ZR6 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 51016924 CC(C)n1cc2C[C@@H]3[C@H](C[C@@H](COC(=O)C4CC4)CN3C)c3cccc1c23 InChI=1S/C23H30N2O2/c1-14(2)25-12-17-10-21-19(18-5-4-6-20(25)22(17)18)9-15(11-24(21)3)13-27-23(26)16-7-8-16/h4-6,12,14-16,19,21H,7-11,13H2,1-3H3/t15-,19-,21-/m1/s1 WAFXAEGTAKCBCH-QFIXIFRTSA-N 50408824 CHAULMOOGRIC ACID::CHEBI:61391::Chaulmoogric Acid Serine/threonine-protein phosphatase 5 1.3 ChEMBL 10.7270/Q2WD44RV 34156850 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408824 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408824&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 10642679 163357848 CHEMBL347660 ZINC13793956 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 1S95,1WAO,3H60,3H61,3H62,3H63,3H64,3H66,3H67,3H68,3H69,4JA7,4JA9,4ZVZ,4ZX2,5HPE,5UI1,5WG8,7ZR5,7ZR6 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 51537246 CN1CCN(CC1)C(=O)[C@@H]1[C@H]2CC[C@H](O2)[C@@H]1C(O)=O InChI=1S/C13H20N2O4/c1-14-4-6-15(7-5-14)12(16)10-8-2-3-9(19-8)11(10)13(17)18/h8-11H,2-7H2,1H3,(H,17,18)/t8-,9+,10-,11+/m1/s1 JUQMLSGOTNKJKI-YTWAJWBKSA-N 50618390 CHEMBL5415208 Serine/threonine-protein phosphatase 5 Homo sapiens 1800 ChEMBL 10.1016/j.ejmech.2023.115350 10.7270/Q2TQ65W9 37054560 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50618390 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50618390&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search LB1 5WG8 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 7ZR6,7ZR5,4JA9,4JA7,5WG8,5UI1,4ZX2,4ZVZ,1S95,5HPE,3H69,3H68,3H67,3H66,3H64,3H63,3H62,3H61,3H60,1A17 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 51537247 C[C@]12[C@@H]3CC[C@@H](O3)[C@@]1(C)C(=O)OC2=O InChI=1S/C10H12O4/c1-9-5-3-4-6(13-5)10(9,2)8(12)14-7(9)11/h5-6H,3-4H2,1-2H3/t5-,6+,9+,10- DHZBEENLJMYSHQ-XCVPVQRUSA-N 50090505 (1R,2S,6R,7S)-2,6-Dimethyl-4,10-dioxa-tricyclo[5.2.1.0*2,6*]decane-3,5-dione::(1R,7S)-2,6-Dimethyl-4,10-dioxa-tricyclo[5.2.1.0*2,6*]decane-3,5-dione::(1S,2R,6S,7R)-2,6-Dimethyl-4,10-dioxa-tricyclo[5.2.1.0*2,6*]decane-3,5-dione::(1S,3S,4R,7R)-2,6-dimethyl-4,10-dioxa-tricyclo[5.2.1.0-2,6]decane-3,5-dione::CANTHARIDIN::CHEMBL48449::cid_6708701 Serine/threonine-protein phosphatase 5 Homo sapiens 600 ChEMBL 10.1016/j.ejmech.2023.115350 10.7270/Q2TQ65W9 37054560 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090505 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090505&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 5944 103988982 64213 CHEMBL48449 C16778 ZINC17611186 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 7ZR6,7ZR5,4JA9,4JA7,5WG8,5UI1,4ZX2,4ZVZ,1S95,5HPE,3H69,3H68,3H67,3H66,3H64,3H63,3H62,3H61,3H60,1A17 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 51537249 C[C@@](O)(\C=C\[C@H]1CC=CC(=O)O1)[C@@H](C[C@@H](O)\C=C/C=C\C=C\CO)OP(O)(O)=O InChI=1S/C19H27O9P/c1-19(23,12-11-16-9-7-10-18(22)27-16)17(28-29(24,25)26)14-15(21)8-5-3-2-4-6-13-20/h2-8,10-12,15-17,20-21,23H,9,13-14H2,1H3,(H2,24,25,26)/b3-2-,6-4+,8-5-,12-11+/t15-,16+,17+,19+/m0/s1 ZMQRJWIYMXZORG-DSWNLJKISA-N 50110690 CHEMBL17377::FOSTRIECIN::Phosphoric acid mono-{3,10-dihydroxy-1-[1-hydroxy-1-methyl-3-(6-oxo-3,6-dihydro-2H-pyran-2-yl)-allyl]-deca-4,6,8-trienyl} ester Serine/threonine-protein phosphatase 5 Homo sapiens >1.000000 ChEMBL 10.1016/j.ejmech.2023.115350 10.7270/Q2TQ65W9 37054560 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50110690 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50110690&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 6913994 104005422 CHEMBL17377 ZINC05707379 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 7ZR6,7ZR5,4JA9,4JA7,5WG8,5UI1,4ZX2,4ZVZ,1S95,5HPE,3H69,3H68,3H67,3H66,3H64,3H63,3H62,3H61,3H60,1A17 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 51537250 CO[C@@H](Cc1ccccc1)[C@@H](C)\C=C(/C)\C=C\[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](C)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](C)NC(=O)C(=C)N(C)C(=O)CC[C@@H](NC(=O)[C@H]1C)C(O)=O)C(O)=O InChI=1S/C49H74N10O12/c1-26(2)23-37-46(66)58-40(48(69)70)30(6)42(62)55-35(17-14-22-52-49(50)51)45(65)54-34(19-18-27(3)24-28(4)38(71-10)25-33-15-12-11-13-16-33)29(5)41(61)56-36(47(67)68)20-21-39(60)59(9)32(8)44(64)53-31(7)43(63)57-37/h11-13,15-16,18-19,24,26,28-31,34-38,40H,8,14,17,20-23,25H2,1-7,9-10H3,(H,53,64)(H,54,65)(H,55,62)(H,56,61)(H,57,63)(H,58,66)(H,67,68)(H,69,70)(H4,50,51,52)/b19-18+,27-24+/t28-,29-,30-,31+,34-,35-,36+,37-,38-,40+/m0/s1 ZYZCGGRZINLQBL-GWRQVWKTSA-N 50061067 15-(3-Guanidino-propyl)-8-isobutyl-18-((1E,3E)-6-methoxy-3,5-dimethyl-7-phenyl-hepta-1,3-dienyl)-1,5,12,19-tetramethyl-2-methylene-3,6,9,13,16,20,25-heptaoxo-1,4,7,10,14,17,21heptaaza-cyclopentacosane-11,22-dicarboxylic acid::15-(3-Guanidino-propyl)-8-isobutyl-18-(6-methoxy-3,5-dimethyl-7-phenyl-hepta-1,3-dienyl)-1,5,12,19-tetramethyl-2-methylene-3,6,9,13,16,20,25-heptaoxo-1,4,7,10,14,17,21heptaaza-cyclopentacosane-11,22-dicarboxylic acid::8-[3-amino(imino)methylaminopropyl]-15-isobutyl-5-[6-methoxy-3,5-dimethyl-7-phenyl-(1E,3E)-1,3-heptadienyl]-4,11,18,22-tetramethyl-21-methylene-3,7,10,14,17,20,23-heptaoxo-2,6,9,13,16,19,22-heptaazacyclopentacosane-1,12-dicarboxylic acid::CHEMBL444092::Microcystin-LR Serine/threonine-protein phosphatase 5 Homo sapiens 1.000000 ChEMBL 10.1016/j.ejmech.2023.115350 10.7270/Q2TQ65W9 37054560 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061067&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 445434 103956654 CHEMBL444092 C05371 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 7ZR6,7ZR5,4JA9,4JA7,5WG8,5UI1,4ZX2,4ZVZ,1S95,5HPE,3H69,3H68,3H67,3H66,3H64,3H63,3H62,3H61,3H60,1A17 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 51537251 C[C@H]1C[C@@H]2O[C@H]1[C@H]([C@H]2C(O)=O)C(O)=O InChI=1S/C9H12O5/c1-3-2-4-5(8(10)11)6(9(12)13)7(3)14-4/h3-7H,2H2,1H3,(H,10,11)(H,12,13)/t3-,4-,5-,6-,7+/m0/s1 YSNMFFYDVUEGJH-AZEWMMITSA-N 50618391 CHEMBL5421006 Serine/threonine-protein phosphatase 5 Homo sapiens 1000 ChEMBL 10.1016/j.ejmech.2023.115350 10.7270/Q2TQ65W9 37054560 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50618391 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50618391&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 4TE 4ZX2 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 7ZR6,7ZR5,4JA9,4JA7,5WG8,5UI1,4ZX2,4ZVZ,1S95,5HPE,3H69,3H68,3H67,3H66,3H64,3H63,3H62,3H61,3H60,1A17 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 51537252 CCCCO[C@H]1C[C@@H]2O[C@H]1[C@H]([C@H]2C(O)=O)C(O)=O InChI=1S/C12H18O6/c1-2-3-4-17-7-5-6-8(11(13)14)9(12(15)16)10(7)18-6/h6-10H,2-5H2,1H3,(H,13,14)(H,15,16)/t6-,7-,8-,9-,10+/m0/s1 DCQZGTQVHYQLJT-BQHMLIOBSA-N 50618392 CHEMBL5405890 Serine/threonine-protein phosphatase 5 Homo sapiens 700 ChEMBL 10.1016/j.ejmech.2023.115350 10.7270/Q2TQ65W9 37054560 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50618392 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50618392&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 7ZR6,7ZR5,4JA9,4JA7,5WG8,5UI1,4ZX2,4ZVZ,1S95,5HPE,3H69,3H68,3H67,3H66,3H64,3H63,3H62,3H61,3H60,1A17 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 51537253 O=C1OC(=O)[C@@H]2[C@H]3CC[C@H](O3)[C@H]12 InChI=1S/C8H8O4/c9-7-5-3-1-2-4(11-3)6(5)8(10)12-7/h3-6H,1-2H2/t3-,4+,5-,6+ JAABVEXCGCXWRR-FBXFSONDSA-N 50090503 (1R,2S,6R,7S)-4,10-Dioxa-tricyclo[5.2.1.0*2,6*]decane-3,5-dione::(1S,2R,6S,7R)-4,10-Dioxa-tricyclo[5.2.1.0*2,6*]decane-3,5-dione::CHEMBL298246::NORCANTHARIDIN::cid_6852411::cid_93004 Serine/threonine-protein phosphatase 5 Homo sapiens 1000 ChEMBL 10.1016/j.ejmech.2023.115350 10.7270/Q2TQ65W9 37054560 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090503 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090503&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 9877482 103988980 CHEMBL298246 ZINC08195636 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 7ZR6,7ZR5,4JA9,4JA7,5WG8,5UI1,4ZX2,4ZVZ,1S95,5HPE,3H69,3H68,3H67,3H66,3H64,3H63,3H62,3H61,3H60,1A17 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 51537256 CC(C)(CO[P@@](O)(=O)O[P@](O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n1cnc2c(N)ncnc12)[C@@H](O)C(=O)NCCC(=O)NCCS InChI=1S/C21H36N7O16P3S/c1-21(2,16(31)19(32)24-4-3-12(29)23-5-6-48)8-41-47(38,39)44-46(36,37)40-7-11-15(43-45(33,34)35)14(30)20(42-11)28-10-27-13-17(22)25-9-26-18(13)28/h9-11,14-16,20,30-31,48H,3-8H2,1-2H3,(H,23,29)(H,24,32)(H,36,37)(H,38,39)(H2,22,25,26)(H2,33,34,35)/t11-,14-,15-,16+,20-/m1/s1 RGJOEKWQDUBAIZ-IBOSZNHHSA-N 50367033 COENZYME_A Serine/threonine-protein phosphatase 5 Homo sapiens 1.000000 ChEMBL 10.1016/j.ejmech.2023.115350 10.7270/Q2TQ65W9 37054560 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367033&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search COA 1XVU,1XVT,6BJA,1YLI,6J1J,6J1I,6J1G,6J1F,6J1E,5CAE,3HO8,2BUE,4NSQ,1F7L,3WXY,1KRU,1HBK,7RIG,6RVB,6RVH,3NWZ,5KP2,5EC4,2VHE,3GY9,3GYA,5JFN,5JFM,5V0Z,1Q2C,1Q2D,6UIA,8GJU,8JL4,2PFR,4U9W,4U9Z,4U9Y,4DPM,5DDK,8Q3D,8Q3T,8Q3S,4BQO,4BQN,3R1K,7WTD,1S7L,1S7N,3DDD,1JKJ,1R31,7KYJ,7KYE,8PN8,6P5U,7LDU,7LDT,7LDW,7LDV,7LDC,7LD2,1BQ6,8JRD,2B58,6MN1,3CTS,3S6H,3ST8,8VDA,8VLI,8VLQ,3TFY,8A9N,8A9O,4L89,4L8A,4M20,2X7B,6CYY,2Q4Y,1H9G,8GQN,1VGR,6I2U,8B32,8B35,8VQW,6N2O,6CZ6,6E1J,8HJB,7N0L,3NTD,3NTA,3NT6,1FY7,1HV9,7S3U,8VZE,2UX9,1XA4,2V1O,2V19,2V18,4EAB,4EAA,4EA8,4EA7,3R5C,3F8K,8GK8,2JBZ,7ED0,7ED1,5G1F,2EIS,2OZG,5US1,5EO2,6PAV,6NDS,4X5K,1S60,6VUM,5JRH,3RT9,1AJ8,1N8W,1VPM,4MRT,8CMZ,2E6U,6WFK,6WFG,6WF3,2B4D,1SST,2QF7,4RUK,1Y81,1PG4,1PG3,8GDN,6WQC,1JTB,8I8J,4C7H,6SLL,7BCZ,7MQM,8W0L,6YUS,3U9E,4PSW,4PSX,7B4S,7B4R,7XAY,2H7C,4JD3,8OG2,6VOU,7N8E,1Q4S,6BOO,3FSB,3FSC,8U2U,8U2T,6B3T,8P5S,8P5U,2ZW5,2ZW4,2ZW7,6L7J,5YO9,2C43,4ZRB,2WKT,2WKV,6XBT,7N8M,7N8L,7XWV,2ONF,6P7K,4U89,4QVH,3U9S,5XXS,4IEN,6HSJ,6HSP,7L3Q,7LIW,3Q9N,3Q9U,1YQZ,4EU8,4EU9,4EU6,4EU7,4EU4,4EU5,4EUD,4EUB,4EUA,5EBV,7MST,5MY0,6CT5,5HMN,5GXD,2SCU,5CSL,2TDT,5T02,5U2K,4MFQ,4MFP,3CGC,2CTS,3CGB,3R9E,3R9F,3R9G,3AWJ,4N6B,3X1M,5V3A,4XX0,6B2M,3LBE,6PCC,6PCB,6PCD,2O28,7WX6,4N8I,3S6F,3S6G,7LCA,8E62,4R4U,2WDS,2WDY,2WDO,2VFC,3B8G,4KEC,3QMN,6LQ5,6LQ4,6LQ7,6LQ6,6LQ1,6LQ0,6LQ3,6LQ2,6LQ8,1CM0,2REQ,2A4N,5HWR,5HWP,2B4B,8HEH,2DEB,2C27,3WD7,5AYV,6BON,7RMP,8I40,5HBR,7YPU,1NVL,3GPC,6YSW,7MQL,7MQK,7KVY,5KTD,5KTC,3CGD,1PUA,5EGJ,1A59,3UBM,1Q6Y,5ZAI,4MZU,3LCJ,5XUH,5XUK,5FRD,6MGG,3D2M,7F08,5KF8,5KF9,5KF2,7KES,6LPY,5GI7,5GI6,5GI5,5GI9,5GI8,5GIG,5GII,5GIH,3TO9,8VR7,7UUO,7UUM,7UUL,7O4S,7O4T,2ZBA,5EGL,6K3C,6LPV,3SXN,4R87,4YAK,4RVN,5HT0,7JZS,6BE0,1YSL,1QSN,6WN0,4N8J,7F3T,6QWU,6MN2,3VWE,1KRV,1S5K,3T6S,1T7Q,7Q3A,1JLL,1MJA,1MJ9,6CIQ,1DQ8,4XZ3,1DQA,3VBI,3VBK,3VBM,3VBL,3VBN,3VBP,8E50,3NFD,2QX1,5GCN,7KPS,5ZBA,6B0U,8GXK,3LD2,1DLV,7CIW,7CIX,1IXE,6KSB,5YH7,2QIR,5SZZ,5SZY,5SZV,5SZU,7RYT,8VLU,1KQA,3L92,3OWC,2OI6,8CIW,2NU7,2NU6,2NU9,2NU8,2NUA,4XL4,1WL4,1WLV,6YGD,6YGB,6YGC,8DQR,6R1E,2D52,2RKV,1N71,2VXK,7ZG5,7STX,1YRE,4OCG,2YJ0,6WUK,5VJ1,4PZR,1ESM,7ZKT,4LRT,4JAQ,4JAP,6VFY,1T4C,6J0P,8APQ,2FY4,8PRV,8PRW,2H3W,2H3U,2H3P,3PVY,3D2P,4XYM,4XYL,6NBE,1S3Z,5W40,3MQH,2WLE,2WL5,2WL4,7OWU,7OWO,1M4I,1M4G,1M4D,3BJ8,7PYT,5C88,6L3P,1I1D,6GW3,3SQZ,4R1L,4HZP,4HZD,4HZO,3ICT,3B7K,7LBZ,2PQ8,6ARE,6ARB,4QJK,4QJL,8QZI,3RHS,6IOI,5WX6,5WX7,5WX3,3TO7,3V4E,5KGP,5KGA,5KGJ,7YXM,7YXZ,6RUZ,3ZBN,1P0H,6BC5,6BC3,4EQW,1TIQ,2IL4,3FBU,3CGE,7S42,7S43,7S41,3OTW,4MOB,4MOC,1D6H,5KLQ,5KL9,1BO4,5JBX,4PV6,7O4R,3LNB,3CV2,6UUW,6UUZ,3BJ7,5TVA,5TVJ,8B3C,6QXR,6QXQ,8BIT,2VAT,2CG5,6V8K,4NHD,6VR2,6VR3,3NE7,7CZ3,7WX7,3TW6,7VF0,3PZC,6PGU,5K85,3QDQ,6L2C,7MSS,5XXR,1NDI,7LCL,3WR7,5ICW,8I06,4C2J,3RTG,2GQ3,1PU9,5SUV,2AF4,2AF3,4RS2,5KF1,2D3M,7L81,8GXF,2JIB,2EFT,6QRM,8V4R,4JD6,2CNT,2CNM,4UA3,3ICS,3ICR,7CW5,6QYF,6QYG,2CYE,2VYX,1RJN,3Q0G,6SP0,8SF3,5BSR,2OAS,6PF1,6PFZ,6PFN,4R3L,4R3K,2AHW,2AHV,6MB6,6RCX,4FC7,2PSW,5FAL,6YBQ,6YBP,5O9V,5O9U,3QB8,8GR9,5N1U,7BOR,7RKZ,7KPP,5HH1,5HH0,1QFL,2VU0,4NV7,2YIZ,2P2F,2P2B,2P2J,2NYG,5DBV,6SK1,6SK2,6SKJ,1SCU,5MY2,1H1T,1H16,1H17,5T7E,2F2S,1EBL,1KHR,2WAT,3PNB,2VJK,2VJO,2VJL,2VJM,4UBV,4UBU,4UBT,5CUO,5VXC,1EAB,3F5O,2JFK,6EHJ,5BYU,4KUB,8V8M,8KHL,1ACA,2ZSD,5K18,6KTQ,4X0O,1QR0,3R3A,3R34,4FX9,4ZV3,8SGS,7YJ9,7YJB,2K5T,8JG2,7K0A,8CN0,8CNB,6BVC,7FC7,4O9C,6GZT,6Z5O,1HNH,1HND,2DQZ,6XKA,3TDT,6QFB,7L7Z,3B2S,1Y7U,2PRB,2PR1,3LSJ,1WTF,2X58,6AQP,2P8U,9BKZ,6K8T,4Q38,3WY0,6HXP,6HXQ,6HXN,6HXL,6HXM,6HXJ,6HXH,6HXI,2D5A,7N7P,4EQR,4EQS,2VTZ,6E3A,1YVK,6ADD,7CSJ,7CSI,7CS1,7CS0,4B3J,4B3I,3OXO,5YRR,7ZTK,5F49,5F48,4PK3,4PK2,1CQJ,1CQI,8PN7,6AS5,5BZ4,5UQU,6POE,5K04,8Q26,8Q2Z,6MB9,5IV0,5JPH,2GF6,7BDW,2WH5,6HE0,6HE2,2IBY,2IBU,2IBW,6EDV,6EDD,1MZJ,7YJ6,7YJA,8PS1,5L1N,1P5R,1NL7,7O1I,7O1L,5LKU,3P3I,8G5C,6ZZK,6ZZM,3RQ5,2GYO,5AHS,2HQY,2II4,6ES9,6ESQ,4AG7,4AG9,4L9Z 87642 160846135 15346 C00010 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 7ZR6,7ZR5,4JA9,4JA7,5WG8,5UI1,4ZX2,4ZVZ,1S95,5HPE,3H69,3H68,3H67,3H66,3H64,3H63,3H62,3H61,3H60,1A17 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 51537257 CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- YZXBAPSDXZZRGB-DOFZRALJSA-N 22319 (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid::Arachidonic acid::Arachidonic acid (AA)::CHEMBL15594::[1-14C]Arachidonic acid Serine/threonine-protein phosphatase 5 Homo sapiens 77590 ChEMBL 10.1016/j.ejmech.2023.115350 10.7270/Q2TQ65W9 37054560 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22319 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22319&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search ACD 1VYG,5ECF,6MCZ,1ADL,3V99,3FG4,3OLT,6LX9,8GHD,5CSD,4ZGA,6OII,4QWT,4DE6,2LBV,1DIY,1CVU,3TZI,5J5L,6MD2,6OFY,8H0C,6NBN,3HS5,7WJ1,3KRK,8XGF,1GNJ,4B0N,5FB7,8V6N,1U67 444899 49846134 15843 CHEMBL15594 C00219 ZINC04474696 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 7ZR6,7ZR5,4JA9,4JA7,5WG8,5UI1,4ZX2,4ZVZ,1S95,5HPE,3H69,3H68,3H67,3H66,3H64,3H63,3H62,3H61,3H60,1A17 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2 51537258 OC(=O)CCCCCCCCCCCC[C@@H]1CCC=C1 InChI=1S/C18H32O2/c19-18(20)16-10-8-6-4-2-1-3-5-7-9-13-17-14-11-12-15-17/h11,14,17H,1-10,12-13,15-16H2,(H,19,20)/t17-/m0/s1 XMVQWNRDPAAMJB-KRWDZBQOSA-N 50618394 CHEMBL5402473 Serine/threonine-protein phosphatase 5 Homo sapiens 134500 ChEMBL 10.1016/j.ejmech.2023.115350 10.7270/Q2TQ65W9 37054560 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50618394 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9149&target=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50618394&enzyme=Serine%2Fthreonine-protein+phosphatase+5&column=ki&startPg=0&Increment=50&submit=Search 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 7ZR6,7ZR5,4JA9,4JA7,5WG8,5UI1,4ZX2,4ZVZ,1S95,5HPE,3H69,3H68,3H67,3H66,3H64,3H63,3H62,3H61,3H60,1A17 Serine/threonine-protein phosphatase 5 PPP5_HUMAN P53041 Q16722 Q53XV2