BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 312433 CC(C)(C)NC(=O)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H22N8O3/c1-18(2,3)25-17(29)23-12-7-13(20-10-4-5-10)26-14(22-12)9(8-19-26)6-11-15(27)24-16(28)21-11/h6-8,10,20H,4-5H2,1-3H3,(H2,21,24,27,28)(H2,22,23,25,29)/b11-6- FOSVAKJEVYRJNG-WDZFZDKYSA-N 220044 US9303033, N47, Table 58A, Compound 11 Casein kinase II subunit beta 3824 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220044 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220044&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335753 329995207 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 312434 O=C(Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1cccc(c1)C#N InChI=1S/C21H16N8O3/c22-9-11-2-1-3-12(6-11)19(30)27-16-8-17(24-14-4-5-14)29-18(26-16)13(10-23-29)7-15-20(31)28-21(32)25-15/h1-3,6-8,10,14,24H,4-5H2,(H,26,27,30)(H2,25,28,31,32)/b15-7- XQGMDORSKBUBET-CHHVJCJISA-N 220047 US9303033, Q47, Table 58A, Compound 14 Casein kinase II subunit beta 3745 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220047&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335485 329995210 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 312435 Clc1ccccc1COc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H16ClN7O3/c20-13-4-2-1-3-10(13)9-30-19-24-15-11(7-14-16(28)25-18(29)23-14)8-21-27(15)17(26-19)22-12-5-6-12/h1-4,7-8,12H,5-6,9H2,(H,22,24,26)(H2,23,25,28,29)/b14-7- RGTWCVSQYHMPKJ-AUWJEWJLSA-N 220054 US9303033, D49, Table 59A, Compound 14::US9303033, X47, Table 58A, Compound 21 Casein kinase II subunit beta 19744 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220054 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220054&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335364 329995217 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 312436 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(Nc3cccc(c3)-n3cccn3)nc12 InChI=1S/C22H19N9O2/c32-21-17(27-22(33)29-21)9-13-12-24-31-19(26-14-5-6-14)11-18(28-20(13)31)25-15-3-1-4-16(10-15)30-8-2-7-23-30/h1-4,7-12,14,26H,5-6H2,(H,25,28)(H2,27,29,32,33)/b17-9- SSKYEIYRCQPTEB-MFOYZWKCSA-N 220063 BDBM220095::US9303033, G48, Table 58A, Compound 30 Casein kinase II subunit beta 17316 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220063 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220063&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314843 329995225 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 312437 Cc1ccccc1-c1cc(F)ccc1CNc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C27H24FN7O2/c1-15-4-2-3-5-20(15)21-11-18(28)7-6-16(21)13-29-23-12-24(31-19-8-9-19)35-25(33-23)17(14-30-35)10-22-26(36)34-27(37)32-22/h2-7,10-12,14,19,31H,8-9,13H2,1H3,(H,29,33)(H2,32,34,36,37)/b22-10- KTNMINICNIMBSV-YVNNLAQVSA-N 220066 BDBM220085::US9303033, J48, Table 58A, Compound 33 Casein kinase II subunit beta 4732 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220066&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314761 329995228 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 312438 COc1cccc(NC(=O)Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C21H20N8O4/c1-33-14-4-2-3-13(8-14)24-20(31)27-16-9-17(23-12-5-6-12)29-18(26-16)11(10-22-29)7-15-19(30)28-21(32)25-15/h2-4,7-10,12,23H,5-6H2,1H3,(H2,24,26,27,31)(H2,25,28,30,32)/b15-7- PWHHKCSUBOICJW-CHHVJCJISA-N 220072 US9303033, P48, Table 58A, Compound 39 Casein kinase II subunit beta 31641 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220072&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336180 329995233 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 312439 Clc1ccc(COc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C19H16ClN7O3/c20-12-3-1-10(2-4-12)9-30-19-24-15-11(7-14-16(28)25-18(29)23-14)8-21-27(15)17(26-19)22-13-5-6-13/h1-4,7-8,13H,5-6,9H2,(H,22,24,26)(H2,23,25,28,29)/b14-7- YTWUMEOPIJMKEC-AUWJEWJLSA-N 220057 US9303033, A48, Table 58A, Compound 24::US9303033, G49, Table 59A, Compound 17 Casein kinase II subunit beta 32822 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220057 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220057&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335381 329995220 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384426 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(nc12)-c1ccncc1 InChI=1S/C18H15N7O2/c26-17-14(23-18(27)24-17)7-11-9-20-25-15(21-12-1-2-12)8-13(22-16(11)25)10-3-5-19-6-4-10/h3-9,12,21H,1-2H2,(H2,23,24,26,27)/b14-7- ARRCWYFVFAYVOG-AUWJEWJLSA-N 218937 US9303033, R4, Table 13A, Compound 26::US9303033, T7, Table 22A, Compound 14 Casein kinase II subunit beta 48.7 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218937 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218937&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314173 329994159 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384427 NCc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H19N7O2/c21-9-11-2-1-3-12(6-11)15-8-17(23-14-4-5-14)27-18(24-15)13(10-22-27)7-16-19(28)26-20(29)25-16/h1-3,6-8,10,14,23H,4-5,9,21H2,(H2,25,26,28,29)/b16-7- ZISUUJMBUDBHAI-APSNUPSMSA-N 218938 US9303033, S4, Table 13A, Compound 27::US9303033, U7, Table 22A, Compound 15 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218938 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218938&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314726 329994160 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384428 CC(O)c1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H20N6O3/c1-11(28)12-3-2-4-13(7-12)16-9-18(23-15-5-6-15)27-19(24-16)14(10-22-27)8-17-20(29)26-21(30)25-17/h2-4,7-11,15,23,28H,5-6H2,1H3,(H2,25,26,29,30)/b17-8- YQCAMIDBPMSMNP-IUXPMGMMSA-N 218939 US9303033, T4, Table 13A, Compound 28::US9303033, V7, Table 22A, Compound 16 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218939&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335526 329994161 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384429 CCCS(=O)(=O)Nc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H23N7O4S/c1-2-8-34(32,33)28-16-5-3-4-13(9-16)17-11-19(24-15-6-7-15)29-20(25-17)14(12-23-29)10-18-21(30)27-22(31)26-18/h3-5,9-12,15,24,28H,2,6-8H2,1H3,(H2,26,27,30,31)/b18-10- QNMAYBALDZJMLD-ZDLGFXPLSA-N 218940 US9303033, U4, Table 13A, Compound 29::US9303033, W7, Table 22A, Compound 17 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218940 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218940&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335529 329994162 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384430 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(nc12)-c1cccnc1 InChI=1S/C18H15N7O2/c26-17-14(23-18(27)24-17)6-11-9-20-25-15(21-12-3-4-12)7-13(22-16(11)25)10-2-1-5-19-8-10/h1-2,5-9,12,21H,3-4H2,(H2,23,24,26,27)/b14-6- XQEFJNXNAXDGSD-NSIKDUERSA-N 218941 US9303033, L8, Table 22A, Compound 32::US9303033, V4, Table 13A, Compound 30 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218941 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218941&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 69939731 329994163 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384431 CNc1cc(nc2c(\C=C3/NC(=O)NC3=O)cnn12)-c1cccc(CNC(C)=O)c1 InChI=1S/C20H19N7O3/c1-11(28)22-9-12-4-3-5-13(6-12)15-8-17(21-2)27-18(24-15)14(10-23-27)7-16-19(29)26-20(30)25-16/h3-8,10,21H,9H2,1-2H3,(H,22,28)(H2,25,26,29,30)/b16-7- XQYQZBHTFLLSGY-APSNUPSMSA-N 218942 US9303033, W4, Table 13A, Compound 31 Casein kinase II subunit beta 2084 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218942 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218942&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 121257424 329994164 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384432 CC(=O)c1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H18N6O3/c1-11(28)12-3-2-4-13(7-12)16-9-18(23-15-5-6-15)27-19(24-16)14(10-22-27)8-17-20(29)26-21(30)25-17/h2-4,7-10,15,23H,5-6H2,1H3,(H2,25,26,29,30)/b17-8- KRPPLDPFKPEEGQ-IUXPMGMMSA-N 218943 US9303033, N8, Table 22A, Compound 34::US9303033, X4, Table 13A, Compound 32 Casein kinase II subunit beta 1727.1 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218943 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218943&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335791 329994165 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384433 CCS(=O)(=O)Nc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H21N7O4S/c1-2-33(31,32)27-15-5-3-4-12(8-15)16-10-18(23-14-6-7-14)28-19(24-16)13(11-22-28)9-17-20(29)26-21(30)25-17/h3-5,8-11,14,23,27H,2,6-7H2,1H3,(H2,25,26,29,30)/b17-9- HNIVOJFJRSBYRQ-MFOYZWKCSA-N 218944 US9303033, O8, Table 22A, Compound 35::US9303033, Y4, Table 13A, Compound 33 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218944 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218944&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335862 329994166 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384434 CCCCS(=O)(=O)Nc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H25N7O4S/c1-2-3-9-35(33,34)29-17-6-4-5-14(10-17)18-12-20(25-16-7-8-16)30-21(26-18)15(13-24-30)11-19-22(31)28-23(32)27-19/h4-6,10-13,16,25,29H,2-3,7-9H2,1H3,(H2,27,28,31,32)/b19-11- GXHQMIBFFXQKHU-ODLFYWEKSA-N 218945 US9303033, P8, Table 22A, Compound 36::US9303033, Z4, Table 13A, Compound 34 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218945 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218945&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335153 329994167 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384435 COc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H18N6O3/c1-29-14-4-2-3-11(7-14)15-9-17(22-13-5-6-13)26-18(23-15)12(10-21-26)8-16-19(27)25-20(28)24-16/h2-4,7-10,13,22H,5-6H2,1H3,(H2,24,25,27,28)/b16-8- RQSCESHOBLOQAK-PXNMLYILSA-N 218947 US9303033, B5, Table 13A, Compound 36::US9303033, Y7, Table 22A, Compound 19 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218947&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335649 329994169 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384436 CN(c1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)S(C)(=O)=O InChI=1S/C21H21N7O4S/c1-27(33(2,31)32)15-5-3-4-12(8-15)16-10-18(23-14-6-7-14)28-19(24-16)13(11-22-28)9-17-20(29)26-21(30)25-17/h3-5,8-11,14,23H,6-7H2,1-2H3,(H2,25,26,29,30)/b17-9- MXWCUIKTJNSLSS-MFOYZWKCSA-N 218948 US9303033, C5, Table 13A, Compound 37::US9303033, Q8, Table 22A, Compound 37 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218948&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335846 329994170 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384437 CC(C)N1CCN(CC1)C(=O)c1cc(ccc1F)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C27H29FN8O3/c1-15(2)34-7-9-35(10-8-34)26(38)19-11-16(3-6-20(19)28)21-13-23(30-18-4-5-18)36-24(31-21)17(14-29-36)12-22-25(37)33-27(39)32-22/h3,6,11-15,18,30H,4-5,7-10H2,1-2H3,(H2,32,33,37,39)/b22-12- LJWNQQUWFRYAPJ-UUYOSTAYSA-N 218949 US9303033, D5, Table 14A, Compound 1 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218949 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218949&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 69939979 329994171 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384438 Fc1ccc(cc1C(=O)NCCN1CCCC1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C26H27FN8O3/c27-19-6-3-15(11-18(19)24(36)28-7-10-34-8-1-2-9-34)20-13-22(30-17-4-5-17)35-23(31-20)16(14-29-35)12-21-25(37)33-26(38)32-21/h3,6,11-14,17,30H,1-2,4-5,7-10H2,(H,28,36)(H2,32,33,37,38)/b21-12- KYRNGNYAWZYVQA-MTJSOVHGSA-N 218950 US9303033, E5, Table 14A, Compound 2 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218950&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 69940236 329994172 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384439 Fc1ccc(cc1C(=O)N1CCOCC1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H22FN7O4/c25-17-4-1-13(9-16(17)23(34)31-5-7-36-8-6-31)18-11-20(27-15-2-3-15)32-21(28-18)14(12-26-32)10-19-22(33)30-24(35)29-19/h1,4,9-12,15,27H,2-3,5-8H2,(H2,29,30,33,35)/b19-10- ISHYJVDNHFGZJA-GRSHGNNSSA-N 218951 US9303033, F5, Table 14A, Compound 3 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218951 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218951&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 69939890 329994173 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384440 CN(C)CCNC(=O)c1cc(ccc1F)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H25FN8O3/c1-32(2)8-7-26-22(34)16-9-13(3-6-17(16)25)18-11-20(28-15-4-5-15)33-21(29-18)14(12-27-33)10-19-23(35)31-24(36)30-19/h3,6,9-12,15,28H,4-5,7-8H2,1-2H3,(H,26,34)(H2,30,31,35,36)/b19-10- MIAUMJFXTBLEGC-GRSHGNNSSA-N 218952 US9303033, G5, Table 14A, Compound 4 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218952&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 69940083 329994174 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384441 COc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/SC(=O)NC3=O)c2n1 InChI=1S/C20H17N5O3S/c1-28-14-4-2-3-11(7-14)15-9-17(22-13-5-6-13)25-18(23-15)12(10-21-25)8-16-19(26)24-20(27)29-16/h2-4,7-10,13,22H,5-6H2,1H3,(H,24,26,27)/b16-8- XLSBTYHDGICKDW-PXNMLYILSA-N 218953 US9303033, H5, Table 15A, Compound 1 Casein kinase II subunit beta 815.2 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218953 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218953&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314537 329994175 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384442 Fc1cc(ccn1)-c1cc(NC2CC2)n2ncc(\C=C3/SC(=O)NC3=O)c2n1 InChI=1S/C18H13FN6O2S/c19-14-6-9(3-4-20-14)12-7-15(22-11-1-2-11)25-16(23-12)10(8-21-25)5-13-17(26)24-18(27)28-13/h3-8,11,22H,1-2H2,(H,24,26,27)/b13-5- WFLWSNQOGGYIHH-ACAGNQJTSA-N 218954 US9303033, I5, Table 15A, Compound 2 Casein kinase II subunit beta 217.6 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218954&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313724 329994176 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384443 NCc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/SC(=O)NC3=O)c2n1 InChI=1S/C20H18N6O2S/c21-9-11-2-1-3-12(6-11)15-8-17(23-14-4-5-14)26-18(24-15)13(10-22-26)7-16-19(27)25-20(28)29-16/h1-3,6-8,10,14,23H,4-5,9,21H2,(H,25,27,28)/b16-7- WHTZOSSDLPXHIO-APSNUPSMSA-N 218955 US9303033, J5, Table 15A, Compound 3 Casein kinase II subunit beta 197.8 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218955&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314342 329994177 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384444 Fc1cc(ccn1)-c1cc(NC2CC2)n2ncc(\C=C3/SC(=S)NC3=O)c2n1 InChI=1S/C18H13FN6OS2/c19-14-6-9(3-4-20-14)12-7-15(22-11-1-2-11)25-16(23-12)10(8-21-25)5-13-17(26)24-18(27)28-13/h3-8,11,22H,1-2H2,(H,24,26,27)/b13-5- BTRQSBOYOIKTSH-ACAGNQJTSA-N 218956 US9303033, Example 47, Table 16, Compound 1 Casein kinase II subunit beta 1590.8 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218956 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218956&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314480 329994178 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384445 Clc1cccc(Nc2cc(NC3CCNCC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C21H21ClN8O2/c22-13-2-1-3-15(9-13)25-17-10-18(26-14-4-6-23-7-5-14)30-19(28-17)12(11-24-30)8-16-20(31)29-21(32)27-16/h1-3,8-11,14,23,26H,4-7H2,(H,25,28)(H2,27,29,31,32)/b16-8- ZBIARYMSEFBDPZ-PXNMLYILSA-N 218957 US9303033, K5, Table 17A, Compound 1 Casein kinase II subunit beta 2449.1 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218957&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313822 329994179 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384446 Clc1cccc(Nc2cc(NC3CCN(CC3)C(=O)C3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C25H25ClN8O3/c26-16-2-1-3-18(11-16)28-20-12-21(29-17-6-8-33(9-7-17)24(36)14-4-5-14)34-22(31-20)15(13-27-34)10-19-23(35)32-25(37)30-19/h1-3,10-14,17,29H,4-9H2,(H,28,31)(H2,30,32,35,37)/b19-10- FOXRISWDZDPKJJ-GRSHGNNSSA-N 218958 US9303033, L5, Table 17A, Compound 2 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218958&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315014 329994180 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384447 CC(C)(C)C(=O)N1CCC(CC1)Nc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C26H29ClN8O3/c1-26(2,3)24(37)34-9-7-17(8-10-34)30-21-13-20(29-18-6-4-5-16(27)12-18)32-22-15(14-28-35(21)22)11-19-23(36)33-25(38)31-19/h4-6,11-14,17,30H,7-10H2,1-3H3,(H,29,32)(H2,31,33,36,38)/b19-11- CTYLPKJAZADEPP-ODLFYWEKSA-N 218959 US9303033, M5, Table 17A, Compound 3 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218959&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314609 329994181 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384448 CN(C)C(=O)N1CCC(CC1)Nc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C24H26ClN9O3/c1-32(2)24(37)33-8-6-16(7-9-33)28-20-12-19(27-17-5-3-4-15(25)11-17)30-21-14(13-26-34(20)21)10-18-22(35)31-23(36)29-18/h3-5,10-13,16,28H,6-9H2,1-2H3,(H,27,30)(H2,29,31,35,36)/b18-10- SXWGPUFCHPWVLF-ZDLGFXPLSA-N 218960 US9303033, N5, Table 17A, Compound 4 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218960 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218960&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315132 329994182 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384449 COC(=O)CN1CCC(CC1)Nc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C24H25ClN8O4/c1-37-21(34)13-32-7-5-16(6-8-32)28-20-11-19(27-17-4-2-3-15(25)10-17)30-22-14(12-26-33(20)22)9-18-23(35)31-24(36)29-18/h2-4,9-12,16,28H,5-8,13H2,1H3,(H,27,30)(H2,29,31,35,36)/b18-9- CMEKOUBOAMAVPS-NVMNQCDNSA-N 218961 US9303033, O5, Table 17A, Compound 5 Casein kinase II subunit beta 2407.6 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218961&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314558 329994183 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384450 OCCN1CCC(CC1)Nc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C23H25ClN8O3/c24-15-2-1-3-17(11-15)26-19-12-20(27-16-4-6-31(7-5-16)8-9-33)32-21(29-19)14(13-25-32)10-18-22(34)30-23(35)28-18/h1-3,10-13,16,27,33H,4-9H2,(H,26,29)(H2,28,30,34,35)/b18-10- HPPUSHYQBOAMHB-ZDLGFXPLSA-N 218962 US9303033, P5, Table 17A, Compound 6 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218962 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218962&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314925 329994184 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384451 CC(C)N1CCC(CC1)Nc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C24H27ClN8O2/c1-14(2)32-8-6-17(7-9-32)28-21-12-20(27-18-5-3-4-16(25)11-18)30-22-15(13-26-33(21)22)10-19-23(34)31-24(35)29-19/h3-5,10-14,17,28H,6-9H2,1-2H3,(H,27,30)(H2,29,31,34,35)/b19-10- UDCZVRDJFWMRPJ-GRSHGNNSSA-N 218963 US9303033, Q5, Table 17A, Compound 7 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218963 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218963&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315084 329994185 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384452 CC(C)CN1CCC(CC1)Nc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C25H29ClN8O2/c1-15(2)14-33-8-6-18(7-9-33)29-22-12-21(28-19-5-3-4-17(26)11-19)31-23-16(13-27-34(22)23)10-20-24(35)32-25(36)30-20/h3-5,10-13,15,18,29H,6-9,14H2,1-2H3,(H,28,31)(H2,30,32,35,36)/b20-10- LRTHZQDNWNHQEF-JMIUGGIZSA-N 218964 US9303033, R5, Table 17A, Compound 8 Casein kinase II subunit beta 2204.6 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218964 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218964&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314733 329994186 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384453 CC(C)(C)CC(=O)N1CCC(CC1)Nc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C27H31ClN8O3/c1-27(2,3)14-23(37)35-9-7-18(8-10-35)31-22-13-21(30-19-6-4-5-17(28)12-19)33-24-16(15-29-36(22)24)11-20-25(38)34-26(39)32-20/h4-6,11-13,15,18,31H,7-10,14H2,1-3H3,(H,30,33)(H2,32,34,38,39)/b20-11- DIPPWXLRITWEKX-JAIQZWGSSA-N 218965 US9303033, S5, Table 17A, Compound 9 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218965 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218965&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315037 329994187 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384454 COC(=O)N1CCC(CC1)Nc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C23H23ClN8O4/c1-36-23(35)31-7-5-15(6-8-31)27-19-11-18(26-16-4-2-3-14(24)10-16)29-20-13(12-25-32(19)20)9-17-21(33)30-22(34)28-17/h2-4,9-12,15,27H,5-8H2,1H3,(H,26,29)(H2,28,30,33,34)/b17-9- QCZVZZYVDRCHCO-MFOYZWKCSA-N 218966 US9303033, T5, Table 17A, Compound 10 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218966 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218966&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314532 329994188 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384455 CC(O)CN1CCC(CC1)Nc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C24H27ClN8O3/c1-14(34)13-32-7-5-17(6-8-32)28-21-11-20(27-18-4-2-3-16(25)10-18)30-22-15(12-26-33(21)22)9-19-23(35)31-24(36)29-19/h2-4,9-12,14,17,28,34H,5-8,13H2,1H3,(H,27,30)(H2,29,31,35,36)/b19-9- KXDJGIBKGUMEAO-OCKHKDLRSA-N 218967 US9303033, U5, Table 17A, Compound 11 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218967 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218967&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314626 329994189 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384456 Clc1cccc(Nc2cc(NC3CCN(Cc4ccccn4)CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C27H26ClN9O2/c28-18-4-3-6-20(13-18)31-23-14-24(32-19-7-10-36(11-8-19)16-21-5-1-2-9-29-21)37-25(34-23)17(15-30-37)12-22-26(38)35-27(39)33-22/h1-6,9,12-15,19,32H,7-8,10-11,16H2,(H,31,34)(H2,33,35,38,39)/b22-12- HZVAGBTZTFEQCQ-UUYOSTAYSA-N 218968 US9303033, V5, Table 17A, Compound 12 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218968 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218968&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313807 329994190 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384457 CCN1CCC(CC1)Nc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C23H25ClN8O2/c1-2-31-8-6-16(7-9-31)27-20-12-19(26-17-5-3-4-15(24)11-17)29-21-14(13-25-32(20)21)10-18-22(33)30-23(34)28-18/h3-5,10-13,16,27H,2,6-9H2,1H3,(H,26,29)(H2,28,30,33,34)/b18-10- QUYPCSPJAVHSEC-ZDLGFXPLSA-N 218969 US9303033, W5, Table 17A, Compound 13 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218969 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218969&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314326 329994191 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384458 Clc1cccc(Nc2cc(SCc3ccccc3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C23H17ClN6O2S/c24-16-7-4-8-17(10-16)26-19-11-20(33-13-14-5-2-1-3-6-14)30-21(28-19)15(12-25-30)9-18-22(31)29-23(32)27-18/h1-12H,13H2,(H,26,28)(H2,27,29,31,32)/b18-9- PDLOCRAPDHMXQX-NVMNQCDNSA-N 218970 US9303033, X5, Table 18A, Compound 1 Casein kinase II subunit beta 2244.9 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218970 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218970&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 69939720 329994192 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384459 Clc1cccc(c1)-c1cc(SCc2ccccc2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H16ClN5O2S/c24-17-8-4-7-15(9-17)18-11-20(32-13-14-5-2-1-3-6-14)29-21(26-18)16(12-25-29)10-19-22(30)28-23(31)27-19/h1-12H,13H2,(H2,27,28,30,31)/b19-10- CRNCPYXWRABZJN-GRSHGNNSSA-N 218971 US9303033, Y5, Table 18A, Compound 2 Casein kinase II subunit beta 291.3 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218971&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335533 329994193 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384460 Clc1cccc(Nc2cc(S(=O)Cc3ccccc3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C23H17ClN6O3S/c24-16-7-4-8-17(10-16)26-19-11-20(34(33)13-14-5-2-1-3-6-14)30-21(28-19)15(12-25-30)9-18-22(31)29-23(32)27-18/h1-12H,13H2,(H,26,28)(H2,27,29,31,32)/b18-9- IDMQTYIRKCOHHQ-NVMNQCDNSA-N 218972 US9303033, Z5, Table 18A, Compound 3 Casein kinase II subunit beta 296.8 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218972 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218972&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313888 329994194 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384461 Clc1cccc(c1)-c1cc(S(=O)Cc2ccccc2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H16ClN5O3S/c24-17-8-4-7-15(9-17)18-11-20(33(32)13-14-5-2-1-3-6-14)29-21(26-18)16(12-25-29)10-19-22(30)28-23(31)27-19/h1-12H,13H2,(H2,27,28,30,31)/b19-10- VQIJPCMGEFWSFF-GRSHGNNSSA-N 218973 US9303033, A6, Table 18A, Compound 4 Casein kinase II subunit beta 209 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218973 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218973&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335808 329994195 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384462 Clc1cccc(Nc2cc(NC3CCCC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C21H20ClN7O2/c22-13-4-3-7-15(9-13)24-17-10-18(25-14-5-1-2-6-14)29-19(27-17)12(11-23-29)8-16-20(30)28-21(31)26-16/h3-4,7-11,14,25H,1-2,5-6H2,(H,24,27)(H2,26,28,30,31)/b16-8- CSCUBDRFNYDEGI-PXNMLYILSA-N 218974 US9303033, B6, Table 19A, Compound 1 Casein kinase II subunit beta 342.6 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218974&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335898 329994196 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384463 CCOCCNc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C20H20ClN7O3/c1-2-31-7-6-22-17-10-16(24-14-5-3-4-13(21)9-14)26-18-12(11-23-28(17)18)8-15-19(29)27-20(30)25-15/h3-5,8-11,22H,2,6-7H2,1H3,(H,24,26)(H2,25,27,29,30)/b15-8- QLNUOLQEAOVNDC-NVNXTCNLSA-N 218975 US9303033, C6, Table 19A, Compound 2 Casein kinase II subunit beta 469 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218975&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335157 329994197 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384464 OCCNc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C18H16ClN7O3/c19-11-2-1-3-12(7-11)22-14-8-15(20-4-5-27)26-16(24-14)10(9-21-26)6-13-17(28)25-18(29)23-13/h1-3,6-9,20,27H,4-5H2,(H,22,24)(H2,23,25,28,29)/b13-6- QRUKIJPRRWPKJB-MLPAPPSSSA-N 218976 US9303033, D6, Table 19A, Compound 3 Casein kinase II subunit beta 474.7 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218976 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218976&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315039 329994198 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384465 Clc1cccc(Nc2cc(NCc3ccncc3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C22H17ClN8O2/c23-15-2-1-3-16(9-15)27-18-10-19(25-11-13-4-6-24-7-5-13)31-20(29-18)14(12-26-31)8-17-21(32)30-22(33)28-17/h1-10,12,25H,11H2,(H,27,29)(H2,28,30,32,33)/b17-8- YVHWWKZTRIBRAL-IUXPMGMMSA-N 218977 US9303033, E6, Table 19A, Compound 4 Casein kinase II subunit beta 1334.5 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218977 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218977&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314109 329994199 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384466 CC(C)Nc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C19H18ClN7O2/c1-10(2)22-16-8-15(23-13-5-3-4-12(20)7-13)25-17-11(9-21-27(16)17)6-14-18(28)26-19(29)24-14/h3-10,22H,1-2H3,(H,23,25)(H2,24,26,28,29)/b14-6- OQOIPBZADVDXLX-NSIKDUERSA-N 218978 US9303033, F6, Table 19A, Compound 5 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218978&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314373 329994200 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384467 Clc1cccc(Nc2cc(NC3CCC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C20H18ClN7O2/c21-12-3-1-6-14(8-12)23-16-9-17(24-13-4-2-5-13)28-18(26-16)11(10-22-28)7-15-19(29)27-20(30)25-15/h1,3,6-10,13,24H,2,4-5H2,(H,23,26)(H2,25,27,29,30)/b15-7- DQUDAYSESGJUCK-CHHVJCJISA-N 218979 US9303033, G6, Table 19A, Compound 6 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218979 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218979&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 53240861 329994201 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384468 Clc1cccc(Nc2cc(NCc3ccccn3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C22H17ClN8O2/c23-14-4-3-6-15(9-14)27-18-10-19(25-12-16-5-1-2-7-24-16)31-20(29-18)13(11-26-31)8-17-21(32)30-22(33)28-17/h1-11,25H,12H2,(H,27,29)(H2,28,30,32,33)/b17-8- CHEJAVBQMRDDMQ-IUXPMGMMSA-N 218980 US9303033, H6, Table 19A, Compound 7 Casein kinase II subunit beta 421.1 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218980 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218980&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314591 329994202 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384469 Clc1cccc(Nc2cc(NCc3cccnc3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C22H17ClN8O2/c23-15-4-1-5-16(8-15)27-18-9-19(25-11-13-3-2-6-24-10-13)31-20(29-18)14(12-26-31)7-17-21(32)30-22(33)28-17/h1-10,12,25H,11H2,(H,27,29)(H2,28,30,32,33)/b17-7- ZAMGAZXHXFGZLU-IDUWFGFVSA-N 218981 US9303033, I6, Table 19A, Compound 8 Casein kinase II subunit beta 704.1 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218981 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218981&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314619 329994203 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384470 CN(C)CCNc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C20H21ClN8O2/c1-28(2)7-6-22-17-10-16(24-14-5-3-4-13(21)9-14)26-18-12(11-23-29(17)18)8-15-19(30)27-20(31)25-15/h3-5,8-11,22H,6-7H2,1-2H3,(H,24,26)(H2,25,27,30,31)/b15-8- OPHSVEZOMFPCFL-NVNXTCNLSA-N 218982 US9303033, J6, Table 19A, Compound 9 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218982 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218982&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314759 329994204 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384471 CC(O)CNc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C19H18ClN7O3/c1-10(28)8-21-16-7-15(23-13-4-2-3-12(20)6-13)25-17-11(9-22-27(16)17)5-14-18(29)26-19(30)24-14/h2-7,9-10,21,28H,8H2,1H3,(H,23,25)(H2,24,26,29,30)/b14-5- FQKAUDSAIMUPLR-RZNTYIFUSA-N 218983 US9303033, K6, Table 19A, Compound 10 Casein kinase II subunit beta 316.5 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218983 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218983&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313990 329994205 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384472 Clc1cccc(Nc2cc(NCCN3CCOCC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C22H23ClN8O3/c23-15-2-1-3-16(11-15)26-18-12-19(24-4-5-30-6-8-34-9-7-30)31-20(28-18)14(13-25-31)10-17-21(32)29-22(33)27-17/h1-3,10-13,24H,4-9H2,(H,26,28)(H2,27,29,32,33)/b17-10- QGWBRJNQQBUZGC-YVLHZVERSA-N 218984 US9303033, L6, Table 19A, Compound 11 Casein kinase II subunit beta 2190.5 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218984&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314082 329994206 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384473 CN(C)CC(C)(C)CNc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C23H27ClN8O2/c1-23(2,13-31(3)4)12-25-19-10-18(27-16-7-5-6-15(24)9-16)29-20-14(11-26-32(19)20)8-17-21(33)30-22(34)28-17/h5-11,25H,12-13H2,1-4H3,(H,27,29)(H2,28,30,33,34)/b17-8- CLUIWKHLQKDCFB-IUXPMGMMSA-N 218985 US9303033, M6, Table 19A, Compound 12 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218985 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218985&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314690 329994207 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384474 CC(C)(C)OC(=O)N1CCCC1CNc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C26H29ClN8O4/c1-26(2,3)39-25(38)34-9-5-8-18(34)14-28-21-12-20(30-17-7-4-6-16(27)11-17)32-22-15(13-29-35(21)22)10-19-23(36)33-24(37)31-19/h4,6-7,10-13,18,28H,5,8-9,14H2,1-3H3,(H,30,32)(H2,31,33,36,37)/b19-10- BMTJQSQOOQDIQX-GRSHGNNSSA-N 218986 US9303033, N6, Table 19A, Compound 13 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218986 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218986&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313884 329994208 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384475 FC(F)(F)CNc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C18H13ClF3N7O2/c19-10-2-1-3-11(5-10)25-13-6-14(23-8-18(20,21)22)29-15(27-13)9(7-24-29)4-12-16(30)28-17(31)26-12/h1-7,23H,8H2,(H,25,27)(H2,26,28,30,31)/b12-4- XBRHZZLPSZOZES-QCDXTXTGSA-N 218987 US9303033, O6, Table 19A, Compound 14 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218987 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218987&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314811 329994209 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384476 Clc1cccc(Nc2cc(NC3CCNC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C20H19ClN8O2/c21-12-2-1-3-13(7-12)24-16-8-17(25-14-4-5-22-10-14)29-18(27-16)11(9-23-29)6-15-19(30)28-20(31)26-15/h1-3,6-9,14,22,25H,4-5,10H2,(H,24,27)(H2,26,28,30,31)/b15-6- OWPDNCRGIFXISG-UUASQNMZSA-N 218988 US9303033, P6, Table 19A, Compound 15 Casein kinase II subunit beta 700.8 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218988 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218988&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315097 329994210 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384477 C[C@H](Nc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12)C1CC1 InChI=1S/C21H20ClN7O2/c1-11(12-5-6-12)24-18-9-17(25-15-4-2-3-14(22)8-15)27-19-13(10-23-29(18)19)7-16-20(30)28-21(31)26-16/h2-4,7-12,24H,5-6H2,1H3,(H,25,27)(H2,26,28,30,31)/b16-7-/t11-/m0/s1 ZSWJGFKESRKFDS-FQKZPNAISA-N 218989 US9303033, Q6, Table 19A, Compound 16 Casein kinase II subunit beta 1287.6 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218989 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218989&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335907 329994211 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384478 OCC1(CNc2cc(Nc3cccc(Cl)c3)nc3c(\C=C4/NC(=O)NC4=O)cnn23)CCCC1 InChI=1S/C23H24ClN7O3/c24-15-4-3-5-16(9-15)27-18-10-19(25-12-23(13-32)6-1-2-7-23)31-20(29-18)14(11-26-31)8-17-21(33)30-22(34)28-17/h3-5,8-11,25,32H,1-2,6-7,12-13H2,(H,27,29)(H2,28,30,33,34)/b17-8- IUDFVYOMBLIDOA-IUXPMGMMSA-N 218990 US9303033, R6, Table 19A, Compound 17 Casein kinase II subunit beta 1121.3 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218990 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218990&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335036 329994212 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384479 C[C@@H](Nc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12)C1CC1 InChI=1S/C21H20ClN7O2/c1-11(12-5-6-12)24-18-9-17(25-15-4-2-3-14(22)8-15)27-19-13(10-23-29(18)19)7-16-20(30)28-21(31)26-16/h2-4,7-12,24H,5-6H2,1H3,(H,25,27)(H2,26,28,30,31)/b16-7-/t11-/m1/s1 ZSWJGFKESRKFDS-CRZGJZTJSA-N 218993 US9303033, U6, Table 19A, Compound 20 Casein kinase II subunit beta 514.9 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218993&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 71114249 329994215 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384480 CC(C)(C)OC(=O)c1cccc(Nc2cc(Nc3cccc(Cl)c3)nc3c(\C=C4/NC(=O)NC4=O)cnn23)c1 InChI=1S/C27H24ClN7O4/c1-27(2,3)39-25(37)15-6-4-8-18(10-15)31-22-13-21(30-19-9-5-7-17(28)12-19)33-23-16(14-29-35(22)23)11-20-24(36)34-26(38)32-20/h4-14,31H,1-3H3,(H,30,33)(H2,32,34,36,38)/b20-11- RSZLIFVAAPEQIC-JAIQZWGSSA-N 219000 US9303033, B7, Table 20A, Compound 1 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219000&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67253894 329994222 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384481 CN(C)C1CCN(C1)C(=O)c1cccc(Nc2cc(Nc3cccc(Cl)c3)nc3c(\C=C4/NC(=O)NC4=O)cnn23)c1 InChI=1S/C29H28ClN9O3/c1-37(2)22-9-10-38(16-22)28(41)17-5-3-7-20(11-17)33-25-14-24(32-21-8-4-6-19(30)13-21)35-26-18(15-31-39(25)26)12-23-27(40)36-29(42)34-23/h3-8,11-15,22,33H,9-10,16H2,1-2H3,(H,32,35)(H2,34,36,40,42)/b23-12- RSIPFVAIWWXUID-FMCGGJTJSA-N 219001 US9303033, C7, Table 20A, Compound 2 Casein kinase II subunit beta 1444.6 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219001 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219001&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 69939384 329994223 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384482 OC(=O)c1cccc(Nc2cc(Nc3cccc(Cl)c3)nc3c(\C=C4/NC(=O)NC4=O)cnn23)c1 InChI=1S/C23H16ClN7O4/c24-14-4-2-6-16(9-14)26-18-10-19(27-15-5-1-3-12(7-15)22(33)34)31-20(29-18)13(11-25-31)8-17-21(32)30-23(35)28-17/h1-11,27H,(H,26,29)(H,33,34)(H2,28,30,32,35)/b17-8- WYQDQFWVPFBFQQ-IUXPMGMMSA-N 219002 US9303033, D7, Table 20A, Compound 3 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219002 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219002&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 69939721 329994224 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384483 CC(C)(C)OC(=O)N1CCN(CC1)C(=O)c1cccc(Nc2cc(Nc3cccc(Cl)c3)nc3c(\C=C4/NC(=O)NC4=O)cnn23)c1 InChI=1S/C32H32ClN9O5/c1-32(2,3)47-31(46)41-12-10-40(11-13-41)29(44)19-6-4-8-22(14-19)36-26-17-25(35-23-9-5-7-21(33)16-23)38-27-20(18-34-42(26)27)15-24-28(43)39-30(45)37-24/h4-9,14-18,36H,10-13H2,1-3H3,(H,35,38)(H2,37,39,43,45)/b24-15- UJKVRHBEXRRDPF-IWIPYMOSSA-N 219003 US9303033, E7, Table 20A, Compound 4 Casein kinase II subunit beta 2019.3 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219003 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219003&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67253745 329994225 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384484 Clc1cccc(Nc2cc(Nc3cccc(c3)C(=O)N3CCNCC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C27H24ClN9O3/c28-18-4-2-6-20(13-18)31-22-14-23(32-19-5-1-3-16(11-19)26(39)36-9-7-29-8-10-36)37-24(34-22)17(15-30-37)12-21-25(38)35-27(40)33-21/h1-6,11-15,29,32H,7-10H2,(H,31,34)(H2,33,35,38,40)/b21-12- ZYWPLQQZSRAHDW-MTJSOVHGSA-N 219004 US9303033, F7, Table 20A, Compound 5 Casein kinase II subunit beta 1234.8 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219004 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219004&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335194 329994226 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384485 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(Cc3cccc(c3)C#N)nc12 InChI=1S/C21H17N7O2/c22-10-13-3-1-2-12(6-13)7-16-9-18(24-15-4-5-15)28-19(25-16)14(11-23-28)8-17-20(29)27-21(30)26-17/h1-3,6,8-9,11,15,24H,4-5,7H2,(H2,26,27,29,30)/b17-8- UQXZXMFBZBQPRC-IUXPMGMMSA-N 219005 US9303033, Example 96, Table 21, Compound 1 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219005 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219005&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67216648 329994227 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384486 Oc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H16N6O3/c26-13-3-1-2-10(6-13)14-8-16(21-12-4-5-12)25-17(22-14)11(9-20-25)7-15-18(27)24-19(28)23-15/h1-3,6-9,12,21,26H,4-5H2,(H2,23,24,27,28)/b15-7- LHKXGWCPNBKTJF-CHHVJCJISA-N 218912 US9303033, G7, Table 22A, Compound 1::US9303033, S3, Table 13A, Compound 1 Casein kinase II subunit beta 613.5 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218912 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218912&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 69940306 329994134 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384487 FC(F)(F)Oc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H15F3N6O3/c21-20(22,23)32-13-3-1-2-10(6-13)14-8-16(25-12-4-5-12)29-17(26-14)11(9-24-29)7-15-18(30)28-19(31)27-15/h1-3,6-9,12,25H,4-5H2,(H2,27,28,30,31)/b15-7- NNYBSRTZNHMIIX-CHHVJCJISA-N 218913 US9303033, H7, Table 22A, Compound 2::US9303033, T3, Table 13A, Compound 2 Casein kinase II subunit beta 890.8 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218913 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218913&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 69940617 329994135 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384488 COC(=O)c1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H18N6O4/c1-31-20(29)12-4-2-3-11(7-12)15-9-17(23-14-5-6-14)27-18(24-15)13(10-22-27)8-16-19(28)26-21(30)25-16/h2-4,7-10,14,23H,5-6H2,1H3,(H2,25,26,28,30)/b16-8- HVPPFXPMHYLOKC-PXNMLYILSA-N 218916 US9303033, I7, Table 22A, Compound 3::US9303033, W3, Table 13A, Compound 5 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218916 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218916&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 69939738 329994138 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384489 CS(=O)(=O)c1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H18N6O4S/c1-31(29,30)14-4-2-3-11(7-14)15-9-17(22-13-5-6-13)26-18(23-15)12(10-21-26)8-16-19(27)25-20(28)24-16/h2-4,7-10,13,22H,5-6H2,1H3,(H2,24,25,27,28)/b16-8- LYSQLMKWDVAPMI-PXNMLYILSA-N 218917 US9303033, J7, Table 22A, Compound 4::US9303033, X3, Table 13A, Compound 6 Casein kinase II subunit beta 649.2 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218917&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 69940147 329994139 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384490 CNS(=O)(=O)c1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H19N7O4S/c1-21-32(30,31)14-4-2-3-11(7-14)15-9-17(23-13-5-6-13)27-18(24-15)12(10-22-27)8-16-19(28)26-20(29)25-16/h2-4,7-10,13,21,23H,5-6H2,1H3,(H2,25,26,28,29)/b16-8- ACVJJCQOPQXKOF-PXNMLYILSA-N 218918 US9303033, K7, Table 22A, Compound 5::US9303033, Y3, Table 13A, Compound 7 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218918&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67253335 329994140 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384491 CN(C)CCCOc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H27N7O3/c1-30(2)9-4-10-34-18-6-3-5-15(11-18)19-13-21(26-17-7-8-17)31-22(27-19)16(14-25-31)12-20-23(32)29-24(33)28-20/h3,5-6,11-14,17,26H,4,7-10H2,1-2H3,(H2,28,29,32,33)/b20-12- XYHIAKXKQJOMIP-NDENLUEZSA-N 218919 US9303033, L7, Table 22A, Compound 6::US9303033, Z3, Table 13A, Compound 8 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218919 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218919&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335014 329994141 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384492 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(nc12)-c1cccc(OCCN2CCOCC2)c1 InChI=1S/C25H27N7O4/c33-24-21(29-25(34)30-24)13-17-15-26-32-22(27-18-4-5-18)14-20(28-23(17)32)16-2-1-3-19(12-16)36-11-8-31-6-9-35-10-7-31/h1-3,12-15,18,27H,4-11H2,(H2,29,30,33,34)/b21-13- UVWPUNVBYWZTEH-BKUYFWCQSA-N 218920 US9303033, A4, Table 13A, Compound 9::US9303033, M7, Table 22A, Compound 7 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218920&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335016 329994142 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384493 Cc1cc(COc2cccc(c2)-c2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)no1 InChI=1S/C24H21N7O4/c1-13-7-17(30-35-13)12-34-18-4-2-3-14(8-18)19-10-21(26-16-5-6-16)31-22(27-19)15(11-25-31)9-20-23(32)29-24(33)28-20/h2-4,7-11,16,26H,5-6,12H2,1H3,(H2,28,29,32,33)/b20-9- UXWXYJUNIQAEIC-UKWGHVSLSA-N 218926 US9303033, G4, Table 13A, Compound 15::US9303033, N7, Table 22A, Compound 8 Casein kinase II subunit beta 2214.4 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218926 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218926&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335859 329994148 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384494 O=C(COc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)N1CCCC1 InChI=1S/C25H25N7O4/c33-22(31-8-1-2-9-31)14-36-18-5-3-4-15(10-18)19-12-21(27-17-6-7-17)32-23(28-19)16(13-26-32)11-20-24(34)30-25(35)29-20/h3-5,10-13,17,27H,1-2,6-9,14H2,(H2,29,30,34,35)/b20-11- WHEWGZZABMFCDD-JAIQZWGSSA-N 218927 US9303033, H4, Table 13A, Compound 16::US9303033, O7, Table 22A, Compound 9 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218927 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218927&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335256 329994149 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384495 CN1CCN(Cc2cccc(c2)-c2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)CC1 InChI=1S/C25H28N8O2/c1-31-7-9-32(10-8-31)15-16-3-2-4-17(11-16)20-13-22(27-19-5-6-19)33-23(28-20)18(14-26-33)12-21-24(34)30-25(35)29-21/h2-4,11-14,19,27H,5-10,15H2,1H3,(H2,29,30,34,35)/b21-12- NASXYRSFUJAXCS-MTJSOVHGSA-N 218928 US9303033, I4, Table 13A, Compound 17::US9303033, P7, Table 22A, Compound 10 Casein kinase II subunit beta 2168.5 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218928 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218928&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314157 329994150 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384496 CN(C)c1ccc(cc1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H21N7O2/c1-27(2)15-7-3-12(4-8-15)16-10-18(23-14-5-6-14)28-19(24-16)13(11-22-28)9-17-20(29)26-21(30)25-17/h3-4,7-11,14,23H,5-6H2,1-2H3,(H2,25,26,29,30)/b17-9- UXBZGXCXOAYKLC-MFOYZWKCSA-N 218929 US9303033, J4, Table 13A, Compound 18::US9303033, Q7, Table 22A, Compound 11 Casein kinase II subunit beta 2403.2 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218929 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218929&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 69940163 329994151 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384497 Fc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H15FN6O2/c20-12-3-1-2-10(6-12)14-8-16(22-13-4-5-13)26-17(23-14)11(9-21-26)7-15-18(27)25-19(28)24-15/h1-3,6-9,13,22H,4-5H2,(H2,24,25,27,28)/b15-7- QOLYMTWFVJPYPN-CHHVJCJISA-N 218930 US9303033, K4, Table 13A, Compound 19::US9303033, R7, Table 22A, Compound 12 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218930 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218930&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 69940082 329994152 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384498 CN(C)c1ccc(cn1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H20N8O2/c1-27(2)16-6-3-11(9-21-16)14-8-17(23-13-4-5-13)28-18(24-14)12(10-22-28)7-15-19(29)26-20(30)25-15/h3,6-10,13,23H,4-5H2,1-2H3,(H2,25,26,29,30)/b15-7- UDMJTEJFYBAYJS-CHHVJCJISA-N 218936 US9303033, Q4, Table 13A, Compound 25::US9303033, S7, Table 22A, Compound 13 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218936 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218936&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 69939749 329994158 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384499 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(nc12)-c1ccncc1 InChI=1S/C18H15N7O2/c26-17-14(23-18(27)24-17)7-11-9-20-25-15(21-12-1-2-12)8-13(22-16(11)25)10-3-5-19-6-4-10/h3-9,12,21H,1-2H2,(H2,23,24,26,27)/b14-7- ARRCWYFVFAYVOG-AUWJEWJLSA-N 218937 US9303033, R4, Table 13A, Compound 26::US9303033, T7, Table 22A, Compound 14 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218937 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218937&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314173 329994159 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384500 NCc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H19N7O2/c21-9-11-2-1-3-12(6-11)15-8-17(23-14-4-5-14)27-18(24-15)13(10-22-27)7-16-19(28)26-20(29)25-16/h1-3,6-8,10,14,23H,4-5,9,21H2,(H2,25,26,28,29)/b16-7- ZISUUJMBUDBHAI-APSNUPSMSA-N 218938 US9303033, S4, Table 13A, Compound 27::US9303033, U7, Table 22A, Compound 15 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218938 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218938&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314726 329994160 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384501 CC(O)c1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H20N6O3/c1-11(28)12-3-2-4-13(7-12)16-9-18(23-15-5-6-15)27-19(24-16)14(10-22-27)8-17-20(29)26-21(30)25-17/h2-4,7-11,15,23,28H,5-6H2,1H3,(H2,25,26,29,30)/b17-8- YQCAMIDBPMSMNP-IUXPMGMMSA-N 218939 US9303033, T4, Table 13A, Compound 28::US9303033, V7, Table 22A, Compound 16 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218939&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335526 329994161 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384502 CCCS(=O)(=O)Nc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H23N7O4S/c1-2-8-34(32,33)28-16-5-3-4-13(9-16)17-11-19(24-15-6-7-15)29-20(25-17)14(12-23-29)10-18-21(30)27-22(31)26-18/h3-5,9-12,15,24,28H,2,6-8H2,1H3,(H2,26,27,30,31)/b18-10- QNMAYBALDZJMLD-ZDLGFXPLSA-N 218940 US9303033, U4, Table 13A, Compound 29::US9303033, W7, Table 22A, Compound 17 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218940 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218940&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335529 329994162 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384503 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(nc12)-c1cccc(NS(=O)(=O)C2CC2)c1 InChI=1S/C22H21N7O4S/c30-21-18(26-22(31)27-21)9-13-11-23-29-19(24-14-4-5-14)10-17(25-20(13)29)12-2-1-3-15(8-12)28-34(32,33)16-6-7-16/h1-3,8-11,14,16,24,28H,4-7H2,(H2,26,27,30,31)/b18-9- QUJJOZLQCNXQBZ-NVMNQCDNSA-N 218946 US9303033, A5, Table 13A, Compound 35::US9303033, X7, Table 22A, Compound 18 Casein kinase II subunit beta 867 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218946&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335530 329994168 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384504 COc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H18N6O3/c1-29-14-4-2-3-11(7-14)15-9-17(22-13-5-6-13)26-18(23-15)12(10-21-26)8-16-19(27)25-20(28)24-16/h2-4,7-10,13,22H,5-6H2,1H3,(H2,24,25,27,28)/b16-8- RQSCESHOBLOQAK-PXNMLYILSA-N 218947 US9303033, B5, Table 13A, Compound 36::US9303033, Y7, Table 22A, Compound 19 Casein kinase II subunit beta 1308.2 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218947&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335649 329994169 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384505 NC(=O)c1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H17N7O3/c21-17(28)11-3-1-2-10(6-11)14-8-16(23-13-4-5-13)27-18(24-14)12(9-22-27)7-15-19(29)26-20(30)25-15/h1-3,6-9,13,23H,4-5H2,(H2,21,28)(H2,25,26,29,30)/b15-7- OEJVZJDCQDIZGA-CHHVJCJISA-N 218914 US9303033, U3, Table 13A, Compound 3::US9303033, Z7, Table 22A, Compound 20 Casein kinase II subunit beta 1474.8 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218914&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335018 329994136 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384506 OCc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H18N6O3/c27-10-11-2-1-3-12(6-11)15-8-17(22-14-4-5-14)26-18(23-15)13(9-21-26)7-16-19(28)25-20(29)24-16/h1-3,6-9,14,22,27H,4-5,10H2,(H2,24,25,28,29)/b16-7- XDJDNFVTLAZCED-APSNUPSMSA-N 218915 US9303033, A8, Table 22A, Compound 21::US9303033, V3, Table 13A, Compound 4 Casein kinase II subunit beta 1249.7 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218915 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218915&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 69939970 329994137 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384507 OCCCOc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H22N6O4/c29-7-2-8-32-16-4-1-3-13(9-16)17-11-19(24-15-5-6-15)28-20(25-17)14(12-23-28)10-18-21(30)27-22(31)26-18/h1,3-4,9-12,15,24,29H,2,5-8H2,(H2,26,27,30,31)/b18-10- TXBFPRVTKAITKV-ZDLGFXPLSA-N 218921 US9303033, B4, Table 13A, Compound 10::US9303033, B8, Table 22A, Compound 22 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218921 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218921&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335117 329994143 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384508 CS(=O)(=O)Nc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H19N7O4S/c1-32(30,31)26-14-4-2-3-11(7-14)15-9-17(22-13-5-6-13)27-18(23-15)12(10-21-27)8-16-19(28)25-20(29)24-16/h2-4,7-10,13,22,26H,5-6H2,1H3,(H2,24,25,28,29)/b16-8- XJGIBEVYLAJXHY-PXNMLYILSA-N 218922 US9303033, C4, Table 13A, Compound 11::US9303033, C8, Table 22A, Compound 23 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218922 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218922&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67254249 329994144 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384509 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(nc12)-c1cccc(c1)C#N InChI=1S/C20H15N7O2/c21-9-11-2-1-3-12(6-11)15-8-17(23-14-4-5-14)27-18(24-15)13(10-22-27)7-16-19(28)26-20(29)25-16/h1-3,6-8,10,14,23H,4-5H2,(H2,25,26,28,29)/b16-7- ZDDJUFMUPQETHV-APSNUPSMSA-N 218923 US9303033, D4, Table 13A, Compound 12::US9303033, D8, Table 22A, Compound 24 Casein kinase II subunit beta 75.4 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218923 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218923&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67253406 329994145 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384510 C=CCOc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H20N6O3/c1-2-8-31-16-5-3-4-13(9-16)17-11-19(24-15-6-7-15)28-20(25-17)14(12-23-28)10-18-21(29)27-22(30)26-18/h2-5,9-12,15,24H,1,6-8H2,(H2,26,27,29,30)/b18-10- GQYRYCFHJUAKOP-ZDLGFXPLSA-N 218924 US9303033, E4, Table 13A, Compound 13::US9303033, E8, Table 22A, Compound 25 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218924&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335547 329994146 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384511 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(nc12)-c1cccc(OCC2CC2)c1 InChI=1S/C23H22N6O3/c30-22-19(27-23(31)28-22)9-15-11-24-29-20(25-16-6-7-16)10-18(26-21(15)29)14-2-1-3-17(8-14)32-12-13-4-5-13/h1-3,8-11,13,16,25H,4-7,12H2,(H2,27,28,30,31)/b19-9- ILQVTSAQOCHIRH-OCKHKDLRSA-N 218925 US9303033, F4, Table 13A, Compound 14::US9303033, F8, Table 22A, Compound 26 Casein kinase II subunit beta 256.2 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218925 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218925&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335049 329994147 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384512 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(nc12)-c1cccc(OCC2=NCCN2)c1 InChI=1S/C23H22N8O3/c32-22-18(29-23(33)30-22)9-14-11-26-31-20(27-15-4-5-15)10-17(28-21(14)31)13-2-1-3-16(8-13)34-12-19-24-6-7-25-19/h1-3,8-11,15,27H,4-7,12H2,(H,24,25)(H2,29,30,32,33)/b18-9- HRDNKNMDOIXOCX-NVMNQCDNSA-N 218931 US9303033, G8, Table 22A, Compound 27::US9303033, L4, Table 13A, Compound 20 Casein kinase II subunit beta 48.7 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218931 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218931&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335113 329994153 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384513 Oc1ccc(cc1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H16N6O3/c26-13-5-1-10(2-6-13)14-8-16(21-12-3-4-12)25-17(22-14)11(9-20-25)7-15-18(27)24-19(28)23-15/h1-2,5-9,12,21,26H,3-4H2,(H2,23,24,27,28)/b15-7- QGEGZWRMRSYNPW-CHHVJCJISA-N 218932 US9303033, H8, Table 22A, Compound 28::US9303033, M4, Table 13A, Compound 21 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218932 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218932&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314143 329994154 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384514 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(nc12)-c1cccc(CN2CCOCC2)c1 InChI=1S/C24H25N7O3/c32-23-20(28-24(33)29-23)11-17-13-25-31-21(26-18-4-5-18)12-19(27-22(17)31)16-3-1-2-15(10-16)14-30-6-8-34-9-7-30/h1-3,10-13,18,26H,4-9,14H2,(H2,28,29,32,33)/b20-11- GFDSSUVFRVZXDV-JAIQZWGSSA-N 218933 US9303033, I8, Table 22A, Compound 29::US9303033, N4, Table 13A, Compound 22 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218933 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218933&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315024 329994155 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384515 FC(F)(F)c1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H15F3N6O2/c21-20(22,23)12-3-1-2-10(6-12)14-8-16(25-13-4-5-13)29-17(26-14)11(9-24-29)7-15-18(30)28-19(31)27-15/h1-3,6-9,13,25H,4-5H2,(H2,27,28,30,31)/b15-7- UYTCCVYCCVAMRJ-CHHVJCJISA-N 218934 US9303033, J8, Table 22A, Compound 30::US9303033, O4, Table 13A, Compound 23 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218934 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218934&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335528 329994156 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384516 Fc1cc(ccn1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H14FN7O2/c19-14-6-9(3-4-20-14)12-7-15(22-11-1-2-11)26-16(23-12)10(8-21-26)5-13-17(27)25-18(28)24-13/h3-8,11,22H,1-2H2,(H2,24,25,27,28)/b13-5- NTLUHAJDTISTSQ-ACAGNQJTSA-N 218935 US9303033, K8, Table 22A, Compound 31::US9303033, P4, Table 13A, Compound 24 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218935 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218935&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 69940129 329994157 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384517 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(nc12)-c1cccnc1 InChI=1S/C18H15N7O2/c26-17-14(23-18(27)24-17)6-11-9-20-25-15(21-12-3-4-12)7-13(22-16(11)25)10-2-1-5-19-8-10/h1-2,5-9,12,21H,3-4H2,(H2,23,24,26,27)/b14-6- XQEFJNXNAXDGSD-NSIKDUERSA-N 218941 US9303033, L8, Table 22A, Compound 32::US9303033, V4, Table 13A, Compound 30 Casein kinase II subunit beta 2084 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218941 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218941&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 69939731 329994163 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384518 CC(=O)NCc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H21N7O3/c1-12(30)23-10-13-3-2-4-14(7-13)17-9-19(25-16-5-6-16)29-20(26-17)15(11-24-29)8-18-21(31)28-22(32)27-18/h2-4,7-9,11,16,25H,5-6,10H2,1H3,(H,23,30)(H2,27,28,31,32)/b18-8- ASNXFJCARDJHCO-LSCVHKIXSA-N 219038 US9303033, M8, Table 22A, Compound 33 Casein kinase II subunit beta 1727.1 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219038 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219038&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314812 329994228 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384519 CC(=O)c1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H18N6O3/c1-11(28)12-3-2-4-13(7-12)16-9-18(23-15-5-6-15)27-19(24-16)14(10-22-27)8-17-20(29)26-21(30)25-17/h2-4,7-10,15,23H,5-6H2,1H3,(H2,25,26,29,30)/b17-8- KRPPLDPFKPEEGQ-IUXPMGMMSA-N 218943 US9303033, N8, Table 22A, Compound 34::US9303033, X4, Table 13A, Compound 32 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218943 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218943&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335791 329994165 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384520 CCS(=O)(=O)Nc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H21N7O4S/c1-2-33(31,32)27-15-5-3-4-12(8-15)16-10-18(23-14-6-7-14)28-19(24-16)13(11-22-28)9-17-20(29)26-21(30)25-17/h3-5,8-11,14,23,27H,2,6-7H2,1H3,(H2,25,26,29,30)/b17-9- HNIVOJFJRSBYRQ-MFOYZWKCSA-N 218944 US9303033, O8, Table 22A, Compound 35::US9303033, Y4, Table 13A, Compound 33 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218944 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218944&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335862 329994166 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384521 CN(c1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)S(C)(=O)=O InChI=1S/C21H21N7O4S/c1-27(33(2,31)32)15-5-3-4-12(8-15)16-10-18(23-14-6-7-14)28-19(24-16)13(11-22-28)9-17-20(29)26-21(30)25-17/h3-5,8-11,14,23H,6-7H2,1-2H3,(H2,25,26,29,30)/b17-9- MXWCUIKTJNSLSS-MFOYZWKCSA-N 218948 US9303033, C5, Table 13A, Compound 37::US9303033, Q8, Table 22A, Compound 37 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218948&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335846 329994170 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384522 Cc1cc(cc(C)c1O)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H20N6O3/c1-10-5-12(6-11(2)18(10)28)15-8-17(23-14-3-4-14)27-19(24-15)13(9-22-27)7-16-20(29)26-21(30)25-16/h5-9,14,23,28H,3-4H2,1-2H3,(H2,25,26,29,30)/b16-7- QIZCNBUXRJIWSF-APSNUPSMSA-N 219043 US9303033, R8, Table 22A, Compound 38 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219043&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335531 329994229 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384523 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(nc12)-c1ccc(s1)C#N InChI=1S/C18H13N7O2S/c19-7-11-3-4-14(28-11)12-6-15(21-10-1-2-10)25-16(22-12)9(8-20-25)5-13-17(26)24-18(27)23-13/h3-6,8,10,21H,1-2H2,(H2,23,24,26,27)/b13-5- OMZYMPYXMRQFTL-ACAGNQJTSA-N 219044 US9303033, S8, Table 23A, Compound 1 Casein kinase II subunit beta 1133.6 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219044 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219044&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314860 329994230 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384524 NC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H15N7O3S/c19-15(26)13-4-3-12(29-13)10-6-14(21-9-1-2-9)25-16(22-10)8(7-20-25)5-11-17(27)24-18(28)23-11/h3-7,9,21H,1-2H2,(H2,19,26)(H2,23,24,27,28)/b11-5- BHRWKKAURRAIEP-WZUFQYTHSA-N 219045 US9303033, T8, Table 23A, Compound 2 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219045&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315064 329994231 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384525 CNC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H17N7O3S/c1-20-18(28)14-5-4-13(30-14)11-7-15(22-10-2-3-10)26-16(23-11)9(8-21-26)6-12-17(27)25-19(29)24-12/h4-8,10,22H,2-3H2,1H3,(H,20,28)(H2,24,25,27,29)/b12-6- PRNALXSZGXQRBE-SDQBBNPISA-N 219046 US9303033, U8, Table 23A, Compound 3 Casein kinase II subunit beta 1009.1 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219046&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314908 329994232 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384526 FCCNC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H18FN7O3S/c21-5-6-22-19(30)15-4-3-14(32-15)12-8-16(24-11-1-2-11)28-17(25-12)10(9-23-28)7-13-18(29)27-20(31)26-13/h3-4,7-9,11,24H,1-2,5-6H2,(H,22,30)(H2,26,27,29,31)/b13-7- ANEQVEFJILSYET-QPEQYQDCSA-N 219047 US9303033, V8, Table 23A, Compound 4 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219047&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313982 329994233 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384527 O=C(N1CCCC1)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H21N7O3S/c30-20-15(26-22(32)27-20)9-12-11-23-29-18(24-13-3-4-13)10-14(25-19(12)29)16-5-6-17(33-16)21(31)28-7-1-2-8-28/h5-6,9-11,13,24H,1-4,7-8H2,(H2,26,27,30,32)/b15-9- KQVYKRVHNMVBDJ-DHDCSXOGSA-N 219048 US9303033, M10, Table 23A, Compound 47::US9303033, W8, Table 23A, Compound 5 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219048&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314355 329994234 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384528 O=C(NCC1CC1)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H21N7O3S/c30-20-15(27-22(32)28-20)7-12-10-24-29-18(25-13-3-4-13)8-14(26-19(12)29)16-5-6-17(33-16)21(31)23-9-11-1-2-11/h5-8,10-11,13,25H,1-4,9H2,(H,23,31)(H2,27,28,30,32)/b15-7- LBBGABHYAHRZCY-CHHVJCJISA-N 219049 US9303033, X8, Table 23A, Compound 6 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219049 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219049&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313735 329994235 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384529 FC(F)(F)CNC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H16F3N7O3S/c21-20(22,23)8-24-18(32)14-4-3-13(34-14)11-6-15(26-10-1-2-10)30-16(27-11)9(7-25-30)5-12-17(31)29-19(33)28-12/h3-7,10,26H,1-2,8H2,(H,24,32)(H2,28,29,31,33)/b12-5- KJOFQWZYRQLTKD-XGICHPGQSA-N 219050 US9303033, Y8, Table 23A, Compound 7 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219050 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219050&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315122 329994236 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384530 F[C@H]1CCN(C1)C(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H20FN7O3S/c23-12-5-6-29(10-12)21(32)17-4-3-16(34-17)14-8-18(25-13-1-2-13)30-19(26-14)11(9-24-30)7-15-20(31)28-22(33)27-15/h3-4,7-9,12-13,25H,1-2,5-6,10H2,(H2,27,28,31,33)/b15-7-/t12-/m0/s1 FLYAREOAQOCYCO-CUTJPZLCSA-N 219051 US9303033, Z8, Table 23A, Compound 8 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219051&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314458 329994237 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384531 OC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H14N6O4S/c25-16-11(22-18(28)23-16)5-8-7-19-24-14(20-9-1-2-9)6-10(21-15(8)24)12-3-4-13(29-12)17(26)27/h3-7,9,20H,1-2H2,(H,26,27)(H2,22,23,25,28)/b11-5- LWHJFRNWEABTBQ-WZUFQYTHSA-N 219052 US9303033, A9, Table 23A, Compound 9 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219052 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219052&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314502 329994238 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384532 O=C(N1CCOCC1)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H21N7O4S/c30-20-15(26-22(32)27-20)9-12-11-23-29-18(24-13-1-2-13)10-14(25-19(12)29)16-3-4-17(34-16)21(31)28-5-7-33-8-6-28/h3-4,9-11,13,24H,1-2,5-8H2,(H2,26,27,30,32)/b15-9- USMIXQAARRKNBZ-DHDCSXOGSA-N 219053 US9303033, B9, Table 23A, Compound 10 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219053&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335940 329994239 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384533 CN1CCCN(CC1)C(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H26N8O3S/c1-30-7-2-8-31(10-9-30)23(34)19-6-5-18(36-19)16-12-20(26-15-3-4-15)32-21(27-16)14(13-25-32)11-17-22(33)29-24(35)28-17/h5-6,11-13,15,26H,2-4,7-10H2,1H3,(H2,28,29,33,35)/b17-11- BXKQZVXRZXXNDC-BOPFTXTBSA-N 219054 US9303033, C9, Table 23A, Compound 11 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219054 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219054&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335938 329994240 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384534 OC1CCN(CC1)C(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H23N7O4S/c31-14-5-7-29(8-6-14)22(33)18-4-3-17(35-18)15-10-19(25-13-1-2-13)30-20(26-15)12(11-24-30)9-16-21(32)28-23(34)27-16/h3-4,9-11,13-14,25,31H,1-2,5-8H2,(H2,27,28,32,34)/b16-9- WDEAWKUTKMNXJX-SXGWCWSVSA-N 219055 US9303033, D9, Table 23A, Compound 12 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219055 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219055&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314451 329994241 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384535 CCN1CCN(CC1)C(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H26N8O3S/c1-2-30-7-9-31(10-8-30)23(34)19-6-5-18(36-19)16-12-20(26-15-3-4-15)32-21(27-16)14(13-25-32)11-17-22(33)29-24(35)28-17/h5-6,11-13,15,26H,2-4,7-10H2,1H3,(H2,28,29,33,35)/b17-11- VYIKUMXZYASIEC-BOPFTXTBSA-N 219056 US9303033, E9, Table 23A, Compound 13 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219056 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219056&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315158 329994242 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384536 FC1(F)CCN(CCNC(=O)c2ccc(s2)-c2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)CC1 InChI=1S/C25H26F2N8O3S/c26-25(27)5-8-34(9-6-25)10-7-28-23(37)19-4-3-18(39-19)16-12-20(30-15-1-2-15)35-21(31-16)14(13-29-35)11-17-22(36)33-24(38)32-17/h3-4,11-13,15,30H,1-2,5-10H2,(H,28,37)(H2,32,33,36,38)/b17-11- FLSOGVRCQBFPGP-BOPFTXTBSA-N 219057 US9303033, F9, Table 23A, Compound 14 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219057 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219057&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335552 329994243 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384537 O=C(NCC1CCCO1)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H23N7O4S/c31-21-16(28-23(33)29-21)8-12-10-25-30-19(26-13-3-4-13)9-15(27-20(12)30)17-5-6-18(35-17)22(32)24-11-14-2-1-7-34-14/h5-6,8-10,13-14,26H,1-4,7,11H2,(H,24,32)(H2,28,29,31,33)/b16-8- FMPCJKSNRDMGSK-PXNMLYILSA-N 219058 US9303033, G9, Table 23A, Compound 15::US9303033, L9, Table 23A, Compound 20 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219058 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219058&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335727 329994244 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384538 O=C(NCCCN1CCOCC1)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C25H28N8O4S/c34-23-18(30-25(36)31-23)12-15-14-27-33-21(28-16-2-3-16)13-17(29-22(15)33)19-4-5-20(38-19)24(35)26-6-1-7-32-8-10-37-11-9-32/h4-5,12-14,16,28H,1-3,6-11H2,(H,26,35)(H2,30,31,34,36)/b18-12- RBPFUWNCSAMKRM-PDGQHHTCSA-N 219059 US9303033, H9, Table 23A, Compound 16 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219059 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219059&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335551 329994245 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384539 FC1CN(C1)C(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H18FN7O3S/c22-11-8-28(9-11)20(31)16-4-3-15(33-16)13-6-17(24-12-1-2-12)29-18(25-13)10(7-23-29)5-14-19(30)27-21(32)26-14/h3-7,11-12,24H,1-2,8-9H2,(H2,26,27,30,32)/b14-5- XPPWQTBNKWKDJV-RZNTYIFUSA-N 219060 US9303033, I9, Table 23A, Compound 17 Casein kinase II subunit beta 713.7 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219060 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219060&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313727 329994246 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384540 O=C(N1CC=CC1)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H19N7O3S/c30-20-15(26-22(32)27-20)9-12-11-23-29-18(24-13-3-4-13)10-14(25-19(12)29)16-5-6-17(33-16)21(31)28-7-1-2-8-28/h1-2,5-6,9-11,13,24H,3-4,7-8H2,(H2,26,27,30,32)/b15-9- PUIIMDRUMAEEIG-DHDCSXOGSA-N 219061 US9303033, J9, Table 23A, Compound 18 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219061 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219061&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314124 329994247 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384541 CC1CN(CC(C)O1)C(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H25N7O4S/c1-12-10-30(11-13(2)35-12)23(33)19-6-5-18(36-19)16-8-20(26-15-3-4-15)31-21(27-16)14(9-25-31)7-17-22(32)29-24(34)28-17/h5-9,12-13,15,26H,3-4,10-11H2,1-2H3,(H2,28,29,32,34)/b17-7- WFJYSWPGWQDZTA-IDUWFGFVSA-N 219062 US9303033, K9, Table 23A, Compound 19 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219062 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219062&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314198 329994248 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384542 O=C(NCC1CCCO1)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H23N7O4S/c31-21-16(28-23(33)29-21)8-12-10-25-30-19(26-13-3-4-13)9-15(27-20(12)30)17-5-6-18(35-17)22(32)24-11-14-2-1-7-34-14/h5-6,8-10,13-14,26H,1-4,7,11H2,(H,24,32)(H2,28,29,31,33)/b16-8- FMPCJKSNRDMGSK-PXNMLYILSA-N 219058 US9303033, G9, Table 23A, Compound 15::US9303033, L9, Table 23A, Compound 20 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219058 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219058&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335727 329994244 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384543 OC1CCCN(C1)C(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H23N7O4S/c31-14-2-1-7-29(11-14)22(33)18-6-5-17(35-18)15-9-19(25-13-3-4-13)30-20(26-15)12(10-24-30)8-16-21(32)28-23(34)27-16/h5-6,8-10,13-14,25,31H,1-4,7,11H2,(H2,27,28,32,34)/b16-8- DQCAMSMNDPITOF-PXNMLYILSA-N 219064 US9303033, M9, Table 23A, Compound 21 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219064&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335255 329994249 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384544 CCCN1CCN(CC1)C(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C25H28N8O3S/c1-2-7-31-8-10-32(11-9-31)24(35)20-6-5-19(37-20)17-13-21(27-16-3-4-16)33-22(28-17)15(14-26-33)12-18-23(34)30-25(36)29-18/h5-6,12-14,16,27H,2-4,7-11H2,1H3,(H2,29,30,34,36)/b18-12- DJUUEBMLNWOCIV-PDGQHHTCSA-N 219075 US9303033, X9, Table 23A, Compound 32 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219075 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219075&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335942 329994260 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384545 O=C(NCC1CCCN1)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H24N8O3S/c32-21-16(29-23(34)30-21)8-12-10-26-31-19(27-13-3-4-13)9-15(28-20(12)31)17-5-6-18(35-17)22(33)25-11-14-2-1-7-24-14/h5-6,8-10,13-14,24,27H,1-4,7,11H2,(H,25,33)(H2,29,30,32,34)/b16-8- XFBJBUIXNBCJKJ-PXNMLYILSA-N 219076 US9303033, Y9, Table 23A, Compound 33 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219076&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335864 329994261 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384546 O=C(NCCN1CCCC1)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H26N8O3S/c33-22-17(29-24(35)30-22)11-14-13-26-32-20(27-15-3-4-15)12-16(28-21(14)32)18-5-6-19(36-18)23(34)25-7-10-31-8-1-2-9-31/h5-6,11-13,15,27H,1-4,7-10H2,(H,25,34)(H2,29,30,33,35)/b17-11- HRVRQBTVXHNOKJ-BOPFTXTBSA-N 219077 US9303033, Z9, Table 23A, Compound 34 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219077&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335078 329994262 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384547 CN(C)CC(C)(C)CNC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C25H30N8O3S/c1-25(2,13-32(3)4)12-26-23(35)19-8-7-18(37-19)16-10-20(28-15-5-6-15)33-21(29-16)14(11-27-33)9-17-22(34)31-24(36)30-17/h7-11,15,28H,5-6,12-13H2,1-4H3,(H,26,35)(H2,30,31,34,36)/b17-9- DFDHSBCKQPTUTN-MFOYZWKCSA-N 219078 US9303033, A10, Table 23A, Compound 35 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219078&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89887971 329994263 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384548 CN1CCCC1CCNC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C25H28N8O3S/c1-32-10-2-3-16(32)8-9-26-24(35)20-7-6-19(37-20)17-12-21(28-15-4-5-15)33-22(29-17)14(13-27-33)11-18-23(34)31-25(36)30-18/h6-7,11-13,15-16,28H,2-5,8-10H2,1H3,(H,26,35)(H2,30,31,34,36)/b18-11- ZQDGIDFPBSDDEU-WQRHYEAKSA-N 219079 US9303033, B10, Table 23A, Compound 36 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219079&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335112 329994264 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384549 CN1CCC(CC1)NC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H26N8O3S/c1-31-8-6-15(7-9-31)27-23(34)19-5-4-18(36-19)16-11-20(26-14-2-3-14)32-21(28-16)13(12-25-32)10-17-22(33)30-24(35)29-17/h4-5,10-12,14-15,26H,2-3,6-9H2,1H3,(H,27,34)(H2,29,30,33,35)/b17-10- RTJYTSQWCLQQJH-YVLHZVERSA-N 219080 US9303033, C10, Table 23A, Compound 37 Casein kinase II subunit beta 793.9 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219080&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335951 329994265 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384550 CC(C)[C@H](CO)NC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H25N7O4S/c1-11(2)16(10-31)27-22(33)18-6-5-17(35-18)14-8-19(25-13-3-4-13)30-20(26-14)12(9-24-30)7-15-21(32)29-23(34)28-15/h5-9,11,13,16,25,31H,3-4,10H2,1-2H3,(H,27,33)(H2,28,29,32,34)/b15-7-/t16-/m0/s1 RKZJODBFZIAMNQ-UJPCXNRSSA-N 219081 US9303033, D10, Table 23A, Compound 38 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219081&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313926 329994266 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384551 CCN1CCC[C@H]1CNC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C25H28N8O3S/c1-2-32-9-3-4-16(32)13-26-24(35)20-8-7-19(37-20)17-11-21(28-15-5-6-15)33-22(29-17)14(12-27-33)10-18-23(34)31-25(36)30-18/h7-8,10-12,15-16,28H,2-6,9,13H2,1H3,(H,26,35)(H2,30,31,34,36)/b18-10-/t16-/m0/s1 SBWHUEAJWJVYHV-PMFHANACSA-N 219082 US9303033, E10, Table 23A, Compound 39 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219082&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314818 329994267 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384552 O=C(N1CCC1)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H19N7O3S/c29-19-14(25-21(31)26-19)8-11-10-22-28-17(23-12-2-3-12)9-13(24-18(11)28)15-4-5-16(32-15)20(30)27-6-1-7-27/h4-5,8-10,12,23H,1-3,6-7H2,(H2,25,26,29,31)/b14-8- YGYIYOOLZFHQKD-ZSOIEALJSA-N 219083 US9303033, F10, Table 23A, Compound 40 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219083 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219083&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315140 329994268 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384553 CN(C)CCCN(C)C(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H28N8O3S/c1-30(2)9-4-10-31(3)23(34)19-8-7-18(36-19)16-12-20(26-15-5-6-15)32-21(27-16)14(13-25-32)11-17-22(33)29-24(35)28-17/h7-8,11-13,15,26H,4-6,9-10H2,1-3H3,(H2,28,29,33,35)/b17-11- NZVPFDGQHWKGGW-BOPFTXTBSA-N 219084 US9303033, G10, Table 23A, Compound 41 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219084 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219084&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315180 329994269 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384554 CC(C)NC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H21N7O3S/c1-10(2)23-20(30)16-6-5-15(32-16)13-8-17(24-12-3-4-12)28-18(25-13)11(9-22-28)7-14-19(29)27-21(31)26-14/h5-10,12,24H,3-4H2,1-2H3,(H,23,30)(H2,26,27,29,31)/b14-7- LCLZDSDHMRWEJH-AUWJEWJLSA-N 219085 US9303033, H10, Table 23A, Compound 42 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219085 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219085&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313711 329994270 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384555 CCOCCNC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H23N7O4S/c1-2-33-8-7-23-21(31)17-6-5-16(34-17)14-10-18(25-13-3-4-13)29-19(26-14)12(11-24-29)9-15-20(30)28-22(32)27-15/h5-6,9-11,13,25H,2-4,7-8H2,1H3,(H,23,31)(H2,27,28,30,32)/b15-9- CWPQGHAFRSFDTB-DHDCSXOGSA-N 219086 US9303033, I10, Table 23A, Compound 43 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219086 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219086&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335867 329994271 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384556 N[C@H]1CCN(C1)C(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H22N8O3S/c23-12-5-6-29(10-12)21(32)17-4-3-16(34-17)14-8-18(25-13-1-2-13)30-19(26-14)11(9-24-30)7-15-20(31)28-22(33)27-15/h3-4,7-9,12-13,25H,1-2,5-6,10,23H2,(H2,27,28,31,33)/b15-7-/t12-/m0/s1 GEQZONQAHWYBOO-CUTJPZLCSA-N 219087 US9303033, J10, Table 23A, Compound 44 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219087 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219087&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335956 329994272 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384557 Cc1cnc(CNC(=O)c2ccc(s2)-c2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cn1 InChI=1S/C24H21N9O3S/c1-12-8-26-15(10-25-12)11-27-23(35)19-5-4-18(37-19)16-7-20(29-14-2-3-14)33-21(30-16)13(9-28-33)6-17-22(34)32-24(36)31-17/h4-10,14,29H,2-3,11H2,1H3,(H,27,35)(H2,31,32,34,36)/b17-6- OLLIRIVEZAFGJU-FMQZQXMHSA-N 219088 US9303033, K10, Table 23A, Compound 45 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219088 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219088&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89888234 329994273 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384558 O=C(Nc1cccnc1)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H18N8O3S/c32-21-16(29-23(34)30-21)8-12-10-25-31-19(26-13-3-4-13)9-15(28-20(12)31)17-5-6-18(35-17)22(33)27-14-2-1-7-24-11-14/h1-2,5-11,13,26H,3-4H2,(H,27,33)(H2,29,30,32,34)/b16-8- BUBFDSINQMUVNG-PXNMLYILSA-N 219089 US9303033, L10, Table 23A, Compound 46 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219089 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219089&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335271 329994274 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384559 O=C(N1CCCC1)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H21N7O3S/c30-20-15(26-22(32)27-20)9-12-11-23-29-18(24-13-3-4-13)10-14(25-19(12)29)16-5-6-17(33-16)21(31)28-7-1-2-8-28/h5-6,9-11,13,24H,1-4,7-8H2,(H2,26,27,30,32)/b15-9- KQVYKRVHNMVBDJ-DHDCSXOGSA-N 219048 US9303033, M10, Table 23A, Compound 47::US9303033, W8, Table 23A, Compound 5 Casein kinase II subunit beta 1775.8 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219048&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314355 329994234 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384560 CC1CN(Cc2ccc(s2)-c2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)CC(C)O1 InChI=1S/C24H27N7O3S/c1-13-10-30(11-14(2)34-13)12-17-5-6-20(35-17)18-8-21(26-16-3-4-16)31-22(27-18)15(9-25-31)7-19-23(32)29-24(33)28-19/h5-9,13-14,16,26H,3-4,10-12H2,1-2H3,(H2,28,29,32,33)/b19-7- NNKDGVZPZWFZTD-GXHLCREISA-N 219091 US9303033, N10, Table 23A, Compound 48::US9303033, W13, Table 25A, Compound 5 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219091&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314703 329994275 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384561 COCCNCc1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H23N7O3S/c1-31-7-6-22-11-14-4-5-17(32-14)15-9-18(24-13-2-3-13)28-19(25-15)12(10-23-28)8-16-20(29)27-21(30)26-16/h4-5,8-10,13,22,24H,2-3,6-7,11H2,1H3,(H2,26,27,29,30)/b16-8- LQFKGIDZLUYTQQ-PXNMLYILSA-N 219092 US9303033, O10, Table 23A, Compound 49::US9303033, X13, Table 25A, Compound 6 Casein kinase II subunit beta 1894.4 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219092&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314643 329994276 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384562 Clc1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C17H13ClN6O2S/c18-13-4-3-12(27-13)10-6-14(20-9-1-2-9)24-15(21-10)8(7-19-24)5-11-16(25)23-17(26)22-11/h3-7,9,20H,1-2H2,(H2,22,23,25,26)/b11-5- IJJYBMVKJBLOER-WZUFQYTHSA-N 219093 US9303033, P10, Table 23A, Compound 50 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219093&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335109 329994277 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384563 CC(C)CNC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H23N7O3S/c1-11(2)9-23-21(31)17-6-5-16(33-17)14-8-18(25-13-3-4-13)29-19(26-14)12(10-24-29)7-15-20(30)28-22(32)27-15/h5-8,10-11,13,25H,3-4,9H2,1-2H3,(H,23,31)(H2,27,28,30,32)/b15-7- BVEPWTXIDOVMED-CHHVJCJISA-N 219094 US9303033, Q10, Table 23A, Compound 51 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219094 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219094&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314016 329994278 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384564 O=C(N1CCCOCC1)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H23N7O4S/c31-21-16(27-23(33)28-21)10-13-12-24-30-19(25-14-2-3-14)11-15(26-20(13)30)17-4-5-18(35-17)22(32)29-6-1-8-34-9-7-29/h4-5,10-12,14,25H,1-3,6-9H2,(H2,27,28,31,33)/b16-10- FRVWASJRECDOOX-YBEGLDIGSA-N 219095 US9303033, R10, Table 23A, Compound 52 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219095 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219095&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314406 329994279 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384565 O=C(NCCCCN1CCCC1)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C26H30N8O3S/c35-24-19(31-26(37)32-24)13-16-15-28-34-22(29-17-5-6-17)14-18(30-23(16)34)20-7-8-21(38-20)25(36)27-9-1-2-10-33-11-3-4-12-33/h7-8,13-15,17,29H,1-6,9-12H2,(H,27,36)(H2,31,32,35,37)/b19-13- KXXCKADNMAZNKA-UYRXBGFRSA-N 219096 US9303033, S10, Table 23A, Compound 53 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219096&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313726 329994280 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384566 OCCCNC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H21N7O4S/c29-7-1-6-22-20(31)16-5-4-15(33-16)13-9-17(24-12-2-3-12)28-18(25-13)11(10-23-28)8-14-19(30)27-21(32)26-14/h4-5,8-10,12,24,29H,1-3,6-7H2,(H,22,31)(H2,26,27,30,32)/b14-8- LWBJGIDDACKFMR-ZSOIEALJSA-N 219097 US9303033, T10, Table 23A, Compound 54 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219097&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313916 329994281 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384567 NC1CCN(C1)C(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H22N8O3S/c23-12-5-6-29(10-12)21(32)17-4-3-16(34-17)14-8-18(25-13-1-2-13)30-19(26-14)11(9-24-30)7-15-20(31)28-22(33)27-15/h3-4,7-9,12-13,25H,1-2,5-6,10,23H2,(H2,27,28,31,33)/b15-7- GEQZONQAHWYBOO-CHHVJCJISA-N 219098 US9303033, U10, Table 23A, Compound 55 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219098 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219098&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335969 329994282 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384568 CC(C)N(C)C(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H23N7O3S/c1-11(2)28(3)21(31)17-7-6-16(33-17)14-9-18(24-13-4-5-13)29-19(25-14)12(10-23-29)8-15-20(30)27-22(32)26-15/h6-11,13,24H,4-5H2,1-3H3,(H2,26,27,30,32)/b15-8- UXPAPURHYMPNHW-NVNXTCNLSA-N 219099 US9303033, V10, Table 23A, Compound 56 Casein kinase II subunit beta 2132.1 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219099 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219099&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314830 329994283 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384569 CON(C)C(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H19N7O4S/c1-26(31-2)19(29)15-6-5-14(32-15)12-8-16(22-11-3-4-11)27-17(23-12)10(9-21-27)7-13-18(28)25-20(30)24-13/h5-9,11,22H,3-4H2,1-2H3,(H2,24,25,28,30)/b13-7- BTXSHFMCIJNYGH-QPEQYQDCSA-N 219100 US9303033, W10, Table 23A, Compound 57 Casein kinase II subunit beta 1365.3 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219100 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219100&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 88941262 329994284 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384570 CC(C)(C)OC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H22N6O4S/c1-22(2,3)32-20(30)16-7-6-15(33-16)13-9-17(24-12-4-5-12)28-18(25-13)11(10-23-28)8-14-19(29)27-21(31)26-14/h6-10,12,24H,4-5H2,1-3H3,(H2,26,27,29,31)/b14-8- IDAJFUVFDSPHSQ-ZSOIEALJSA-N 219101 US9303033, X10, Table 23A, Compound 58 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219101&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335287 329994285 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384571 COCCCNC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H23N7O4S/c1-33-8-2-7-23-21(31)17-6-5-16(34-17)14-10-18(25-13-3-4-13)29-19(26-14)12(11-24-29)9-15-20(30)28-22(32)27-15/h5-6,9-11,13,25H,2-4,7-8H2,1H3,(H,23,31)(H2,27,28,30,32)/b15-9- QKGRCJIDELNQER-DHDCSXOGSA-N 219102 US9303033, Y10, Table 23A, Compound 59 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219102 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219102&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314543 329994286 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384572 CN(C)C(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H19N7O3S/c1-26(2)19(29)15-6-5-14(31-15)12-8-16(22-11-3-4-11)27-17(23-12)10(9-21-27)7-13-18(28)25-20(30)24-13/h5-9,11,22H,3-4H2,1-2H3,(H2,24,25,28,30)/b13-7- LZYVCKNXTQVHHF-QPEQYQDCSA-N 219103 BDBM220100::US9303033, Z10, Table 23A, Compound 60 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219103 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219103&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314279 329994287 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384573 O=C(NC1CC1)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H19N7O3S/c29-19-14(26-21(31)27-19)7-10-9-22-28-17(23-11-1-2-11)8-13(25-18(10)28)15-5-6-16(32-15)20(30)24-12-3-4-12/h5-9,11-12,23H,1-4H2,(H,24,30)(H2,26,27,29,31)/b14-7- UBUDPUHHXLRUFS-AUWJEWJLSA-N 219104 US9303033, A11, Table 23A, Compound 61 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219104 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219104&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314847 329994288 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384574 O=C(NC1CCCC1)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H23N7O3S/c31-21-16(28-23(33)29-21)9-12-11-24-30-19(25-14-5-6-14)10-15(27-20(12)30)17-7-8-18(34-17)22(32)26-13-3-1-2-4-13/h7-11,13-14,25H,1-6H2,(H,26,32)(H2,28,29,31,33)/b16-9- CRKQVNNJSLUCHL-SXGWCWSVSA-N 219105 US9303033, B11, Table 23A, Compound 62 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219105 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219105&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314018 329994289 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384575 COCCNC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H21N7O4S/c1-32-7-6-22-20(30)16-5-4-15(33-16)13-9-17(24-12-2-3-12)28-18(25-13)11(10-23-28)8-14-19(29)27-21(31)26-14/h4-5,8-10,12,24H,2-3,6-7H2,1H3,(H,22,30)(H2,26,27,29,31)/b14-8- PLMNMNSCXHXRME-ZSOIEALJSA-N 219106 US9303033, C11, Table 23A, Compound 63 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219106 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219106&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315116 329994290 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384576 F[C@@H]1CCN(C1)C(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H20FN7O3S/c23-12-5-6-29(10-12)21(32)17-4-3-16(34-17)14-8-18(25-13-1-2-13)30-19(26-14)11(9-24-30)7-15-20(31)28-22(33)27-15/h3-4,7-9,12-13,25H,1-2,5-6,10H2,(H2,27,28,31,33)/b15-7-/t12-/m1/s1 FLYAREOAQOCYCO-FKZYXTMDSA-N 219107 US9303033, D11, Table 23A, Compound 64 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219107&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315087 329994291 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384577 CC(O)CNC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H21N7O4S/c1-10(29)8-22-20(31)16-5-4-15(33-16)13-7-17(24-12-2-3-12)28-18(25-13)11(9-23-28)6-14-19(30)27-21(32)26-14/h4-7,9-10,12,24,29H,2-3,8H2,1H3,(H,22,31)(H2,26,27,30,32)/b14-6- SLLZKQNXLBMOAF-NSIKDUERSA-N 219108 US9303033, E11, Table 23A, Compound 65 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219108 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219108&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314737 329994292 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384578 Cc1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H16N6O2S/c1-9-2-5-14(27-9)12-7-15(20-11-3-4-11)24-16(21-12)10(8-19-24)6-13-17(25)23-18(26)22-13/h2,5-8,11,20H,3-4H2,1H3,(H2,22,23,25,26)/b13-6- MLXOKUOCKKDEET-MLPAPPSSSA-N 219109 US9303033, F11, Table 23A, Compound 66 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219109 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219109&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314347 329994293 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384579 CN1CCN(CC1)C(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H24N8O3S/c1-29-6-8-30(9-7-29)22(33)18-5-4-17(35-18)15-11-19(25-14-2-3-14)31-20(26-15)13(12-24-31)10-16-21(32)28-23(34)27-16/h4-5,10-12,14,25H,2-3,6-9H2,1H3,(H2,27,28,32,34)/b16-10- GXUDGXXBRYSSBN-YBEGLDIGSA-N 219110 US9303033, G11, Table 23A, Compound 67 Casein kinase II subunit beta 2044.1 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219110 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219110&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 69940015 329994294 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384580 Cn1ccnc1CNC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H21N9O3S/c1-31-7-6-24-19(31)11-25-22(34)17-5-4-16(36-17)14-9-18(27-13-2-3-13)32-20(28-14)12(10-26-32)8-15-21(33)30-23(35)29-15/h4-10,13,27H,2-3,11H2,1H3,(H,25,34)(H2,29,30,33,35)/b15-8- RXDQFSLUVWCXJL-NVNXTCNLSA-N 219111 US9303033, H11, Table 23A, Compound 68 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219111 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219111&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314088 329994295 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384581 CN(C)C1CCN(C1)C(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H26N8O3S/c1-30(2)15-7-8-31(12-15)23(34)19-6-5-18(36-19)16-10-20(26-14-3-4-14)32-21(27-16)13(11-25-32)9-17-22(33)29-24(35)28-17/h5-6,9-11,14-15,26H,3-4,7-8,12H2,1-2H3,(H2,28,29,33,35)/b17-9- YFULYYOXBLGLKV-MFOYZWKCSA-N 219112 US9303033, I11, Table 23A, Compound 69 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219112 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219112&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314026 329994296 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384582 CCN(CC)CCNC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H28N8O3S/c1-3-31(4-2)10-9-25-23(34)19-8-7-18(36-19)16-12-20(27-15-5-6-15)32-21(28-16)14(13-26-32)11-17-22(33)30-24(35)29-17/h7-8,11-13,15,27H,3-6,9-10H2,1-2H3,(H,25,34)(H2,29,30,33,35)/b17-11- LMQINQAKAQXUCU-BOPFTXTBSA-N 219113 US9303033, J11, Table 23A, Compound 70 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219113 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219113&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335858 329994297 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384583 FC(F)CNC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H17F2N7O3S/c21-15(22)8-23-19(31)14-4-3-13(33-14)11-6-16(25-10-1-2-10)29-17(26-11)9(7-24-29)5-12-18(30)28-20(32)27-12/h3-7,10,15,25H,1-2,8H2,(H,23,31)(H2,27,28,30,32)/b12-5- RQOYDCOIXKOZPW-XGICHPGQSA-N 219114 US9303033, K11, Table 23A, Compound 71 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219114 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219114&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 88941266 329994298 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384584 O=C(NCCCN1CCCC1)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C25H28N8O3S/c34-23-18(30-25(36)31-23)12-15-14-27-33-21(28-16-4-5-16)13-17(29-22(15)33)19-6-7-20(37-19)24(35)26-8-3-11-32-9-1-2-10-32/h6-7,12-14,16,28H,1-5,8-11H2,(H,26,35)(H2,30,31,34,36)/b18-12- FJGVETHXRMTNJZ-PDGQHHTCSA-N 219115 US9303033, L11, Table 23A, Compound 72 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219115 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219115&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335134 329994299 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384585 FC1(F)CCN(CC1)C(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H21F2N7O3S/c24-23(25)5-7-31(8-6-23)21(34)17-4-3-16(36-17)14-10-18(27-13-1-2-13)32-19(28-14)12(11-26-32)9-15-20(33)30-22(35)29-15/h3-4,9-11,13,27H,1-2,5-8H2,(H2,29,30,33,35)/b15-9- SMFJJONDCFRDTF-DHDCSXOGSA-N 219116 US9303033, M11, Table 23A, Compound 73 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219116 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219116&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313890 329994300 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384586 CC1CCN(C1)C(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H23N7O3S/c1-12-6-7-29(11-12)22(32)18-5-4-17(34-18)15-9-19(25-14-2-3-14)30-20(26-15)13(10-24-30)8-16-21(31)28-23(33)27-16/h4-5,8-10,12,14,25H,2-3,6-7,11H2,1H3,(H2,27,28,31,33)/b16-8- PWZVYKHJARKYHF-PXNMLYILSA-N 219117 US9303033, N11, Table 23A, Compound 74 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219117 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219117&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314850 329994301 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384587 O=C(N1CCCCC1)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H23N7O3S/c31-21-16(27-23(33)28-21)10-13-12-24-30-19(25-14-4-5-14)11-15(26-20(13)30)17-6-7-18(34-17)22(32)29-8-2-1-3-9-29/h6-7,10-12,14,25H,1-5,8-9H2,(H2,27,28,31,33)/b16-10- IHCULDHORQREOI-YBEGLDIGSA-N 219118 US9303033, O11, Table 23A, Compound 75 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219118&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315154 329994302 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384588 O=C(N1CCN(CC2CCCO2)CC1)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C27H30N8O4S/c36-25-20(31-27(38)32-25)12-16-14-28-35-23(29-17-3-4-17)13-19(30-24(16)35)21-5-6-22(40-21)26(37)34-9-7-33(8-10-34)15-18-2-1-11-39-18/h5-6,12-14,17-18,29H,1-4,7-11,15H2,(H2,31,32,36,38)/b20-12- KGNBVKNLKBZFMJ-NDENLUEZSA-N 219119 US9303033, P11, Table 23A, Compound 76 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219119 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219119&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315101 329994303 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384589 CN(C)CCCNC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H26N8O3S/c1-30(2)9-3-8-24-22(33)18-7-6-17(35-18)15-11-19(26-14-4-5-14)31-20(27-15)13(12-25-31)10-16-21(32)29-23(34)28-16/h6-7,10-12,14,26H,3-5,8-9H2,1-2H3,(H,24,33)(H2,28,29,32,34)/b16-10- VFGBTEYJKUGRQL-YBEGLDIGSA-N 219120 US9303033, Q11, Table 23A, Compound 77 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219120&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335088 329994304 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384590 CC(=O)N1CCN(CC1)C(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H24N8O4S/c1-13(33)30-6-8-31(9-7-30)23(35)19-5-4-18(37-19)16-11-20(26-15-2-3-15)32-21(27-16)14(12-25-32)10-17-22(34)29-24(36)28-17/h4-5,10-12,15,26H,2-3,6-9H2,1H3,(H2,28,29,34,36)/b17-10- PLOQVCMOMPRCSG-YVLHZVERSA-N 219121 US9303033, R11, Table 23A, Compound 78 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219121&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335158 329994305 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384591 FC1(F)CCN(C1)C(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H19F2N7O3S/c23-22(24)5-6-30(10-22)20(33)16-4-3-15(35-16)13-8-17(26-12-1-2-12)31-18(27-13)11(9-25-31)7-14-19(32)29-21(34)28-14/h3-4,7-9,12,26H,1-2,5-6,10H2,(H2,28,29,32,34)/b14-7- HGJZKQPSRBIOMH-AUWJEWJLSA-N 219122 US9303033, S11, Table 23A, Compound 79 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219122 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219122&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335068 329994306 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384592 O=C(NC1CCNCC1)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H24N8O3S/c32-21-16(29-23(34)30-21)9-12-11-25-31-19(26-13-1-2-13)10-15(28-20(12)31)17-3-4-18(35-17)22(33)27-14-5-7-24-8-6-14/h3-4,9-11,13-14,24,26H,1-2,5-8H2,(H,27,33)(H2,29,30,32,34)/b16-9- LXVMUNFTXQGGDA-SXGWCWSVSA-N 219123 US9303033, T11, Table 23A, Compound 80 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219123 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219123&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335866 329994307 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384593 OC[C@@H]1CCCN1C(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H23N7O4S/c31-11-14-2-1-7-29(14)22(33)18-6-5-17(35-18)15-9-19(25-13-3-4-13)30-20(26-15)12(10-24-30)8-16-21(32)28-23(34)27-16/h5-6,8-10,13-14,25,31H,1-4,7,11H2,(H2,27,28,32,34)/b16-8-/t14-/m0/s1 CEERURAWIAMREQ-XTIFCCNPSA-N 219124 US9303033, U11, Table 23A, Compound 81 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219124 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219124&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335941 329994308 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384594 CN(C)CCNC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H24N8O3S/c1-29(2)8-7-23-21(32)17-6-5-16(34-17)14-10-18(25-13-3-4-13)30-19(26-14)12(11-24-30)9-15-20(31)28-22(33)27-15/h5-6,9-11,13,25H,3-4,7-8H2,1-2H3,(H,23,32)(H2,27,28,31,33)/b15-9- PQVXZUXDDRIWPH-DHDCSXOGSA-N 219125 US9303033, V11, Table 23A, Compound 82 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219125 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219125&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335957 329994309 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384595 OCCNC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H19N7O4S/c28-6-5-21-19(30)15-4-3-14(32-15)12-8-16(23-11-1-2-11)27-17(24-12)10(9-22-27)7-13-18(29)26-20(31)25-13/h3-4,7-9,11,23,28H,1-2,5-6H2,(H,21,30)(H2,25,26,29,31)/b13-7- ZDMJUWLCAAEKDP-QPEQYQDCSA-N 219126 US9303033, W11, Table 23A, Compound 83 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219126 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219126&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335553 329994310 C04080 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384596 NC(=O)C1CN(CCN1)C(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H23N9O4S/c24-19(33)15-10-31(6-5-25-15)22(35)17-4-3-16(37-17)13-8-18(27-12-1-2-12)32-20(28-13)11(9-26-32)7-14-21(34)30-23(36)29-14/h3-4,7-9,12,15,25,27H,1-2,5-6,10H2,(H2,24,33)(H2,29,30,34,36)/b14-7- OGGWSIVTFDIJRH-AUWJEWJLSA-N 219127 US9303033, X11, Table 23A, Compound 84 Casein kinase II subunit beta 1724.5 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219127 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219127&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315062 329994311 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384597 O=C(N1CCNC(=O)C1)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H20N8O4S/c31-18-10-29(6-5-23-18)21(33)16-4-3-15(35-16)13-8-17(25-12-1-2-12)30-19(26-13)11(9-24-30)7-14-20(32)28-22(34)27-14/h3-4,7-9,12,25H,1-2,5-6,10H2,(H,23,31)(H2,27,28,32,34)/b14-7- VTFWUEWPJBSBPS-AUWJEWJLSA-N 219128 US9303033, Y11, Table 23A, Compound 85 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219128&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314982 329994312 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384598 CC1CN(CC(C)N1)C(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H26N8O3S/c1-12-10-31(11-13(2)26-12)23(34)19-6-5-18(36-19)16-8-20(27-15-3-4-15)32-21(28-16)14(9-25-32)7-17-22(33)30-24(35)29-17/h5-9,12-13,15,26-27H,3-4,10-11H2,1-2H3,(H2,29,30,33,35)/b17-7- GJWSSNHOLHTESN-IDUWFGFVSA-N 219129 US9303033, Z11, Table 23A, Compound 86 Casein kinase II subunit beta 1243.4 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219129&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313802 329994313 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384599 COCC1CCCCN1C(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C25H27N7O4S/c1-36-13-16-4-2-3-9-31(16)24(34)20-8-7-19(37-20)17-11-21(27-15-5-6-15)32-22(28-17)14(12-26-32)10-18-23(33)30-25(35)29-18/h7-8,10-12,15-16,27H,2-6,9,13H2,1H3,(H2,29,30,33,35)/b18-10- HKBAJSHQGBBIOQ-ZDLGFXPLSA-N 219130 US9303033, A12, Table 23A, Compound 87 Casein kinase II subunit beta 1439.6 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219130&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335872 329994314 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384600 O=C(NCc1ccncc1)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H20N8O3S/c33-22-17(30-24(35)31-22)9-14-12-27-32-20(28-15-1-2-15)10-16(29-21(14)32)18-3-4-19(36-18)23(34)26-11-13-5-7-25-8-6-13/h3-10,12,15,28H,1-2,11H2,(H,26,34)(H2,30,31,33,35)/b17-9- BTQPOASZRIDJIT-MFOYZWKCSA-N 219131 US9303033, B12, Table 23A, Compound 88 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219131&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335555 329994315 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384601 CCCOCCNC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H25N7O4S/c1-2-8-34-9-7-24-22(32)18-6-5-17(35-18)15-11-19(26-14-3-4-14)30-20(27-15)13(12-25-30)10-16-21(31)29-23(33)28-16/h5-6,10-12,14,26H,2-4,7-9H2,1H3,(H,24,32)(H2,28,29,31,33)/b16-10- ZITVOIZIQJRPAY-YBEGLDIGSA-N 219132 US9303033, C12, Table 23A, Compound 89 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219132&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335723 329994316 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384602 O=C(NC[C@H]1CCCO1)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H23N7O4S/c31-21-16(28-23(33)29-21)8-12-10-25-30-19(26-13-3-4-13)9-15(27-20(12)30)17-5-6-18(35-17)22(32)24-11-14-2-1-7-34-14/h5-6,8-10,13-14,26H,1-4,7,11H2,(H,24,32)(H2,28,29,31,33)/b16-8-/t14-/m1/s1 FMPCJKSNRDMGSK-MEFZMRIGSA-N 219133 US9303033, D12, Table 23A, Compound 90 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219133 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219133&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335554 329994317 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384603 CC(C)OCCCNC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H27N7O4S/c1-13(2)35-9-3-8-25-23(33)19-7-6-18(36-19)16-11-20(27-15-4-5-15)31-21(28-16)14(12-26-31)10-17-22(32)30-24(34)29-17/h6-7,10-13,15,27H,3-5,8-9H2,1-2H3,(H,25,33)(H2,29,30,32,34)/b17-10- AZQRZFLPMDOWHD-YVLHZVERSA-N 219134 US9303033, E12, Table 23A, Compound 91 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219134 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219134&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89888233 329994318 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384604 CC1CCCCN1CCCNC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C27H32N8O3S/c1-16-5-2-3-11-34(16)12-4-10-28-26(37)22-9-8-21(39-22)19-14-23(30-18-6-7-18)35-24(31-19)17(15-29-35)13-20-25(36)33-27(38)32-20/h8-9,13-16,18,30H,2-7,10-12H2,1H3,(H,28,37)(H2,32,33,36,38)/b20-13- ZSAQPHNDHIVGPZ-MOSHPQCFSA-N 219135 US9303033, F12, Table 23A, Compound 92 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219135 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219135&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335282 329994319 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384605 CCN(CC)CCCC(C)NC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C27H34N8O3S/c1-4-34(5-2)12-6-7-16(3)29-26(37)22-11-10-21(39-22)19-14-23(30-18-8-9-18)35-24(31-19)17(15-28-35)13-20-25(36)33-27(38)32-20/h10-11,13-16,18,30H,4-9,12H2,1-3H3,(H,29,37)(H2,32,33,36,38)/b20-13- ZISSHDAZTPBUDE-MOSHPQCFSA-N 219136 US9303033, G12, Table 23A, Compound 93 Casein kinase II subunit beta 810.6 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219136&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335952 329994320 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384606 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(nc12)-c1ccc(CN2CCOCC2)s1 InChI=1S/C22H23N7O3S/c30-21-17(26-22(31)27-21)9-13-11-23-29-19(24-14-1-2-14)10-16(25-20(13)29)18-4-3-15(33-18)12-28-5-7-32-8-6-28/h3-4,9-11,14,24H,1-2,5-8,12H2,(H2,26,27,30,31)/b17-9- OYOCDZLFPKERPX-MFOYZWKCSA-N 219137 US9303033, H12, Table 23A, Compound 94::US9303033, S13, Table 25A, Compound 1 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219137 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219137&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314341 329994321 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384607 CCN1CCCC1CNC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C25H28N8O3S/c1-2-32-9-3-4-16(32)13-26-24(35)20-8-7-19(37-20)17-11-21(28-15-5-6-15)33-22(29-17)14(12-27-33)10-18-23(34)31-25(36)30-18/h7-8,10-12,15-16,28H,2-6,9,13H2,1H3,(H,26,35)(H2,30,31,34,36)/b18-10- SBWHUEAJWJVYHV-ZDLGFXPLSA-N 219138 US9303033, I12, Table 23A, Compound 95 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219138 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219138&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314433 329994322 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384608 CC(C)N1CCN(CC1)C(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C25H28N8O3S/c1-14(2)31-7-9-32(10-8-31)24(35)20-6-5-19(37-20)17-12-21(27-16-3-4-16)33-22(28-17)15(13-26-33)11-18-23(34)30-25(36)29-18/h5-6,11-14,16,27H,3-4,7-10H2,1-2H3,(H2,29,30,34,36)/b18-11- OMMIEGNWYXIZPX-WQRHYEAKSA-N 219139 US9303033, J12, Table 23A, Compound 96 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219139 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219139&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313843 329994323 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384609 FC(F)(F)CCNC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H18F3N7O3S/c22-21(23,24)5-6-25-19(33)15-4-3-14(35-15)12-8-16(27-11-1-2-11)31-17(28-12)10(9-26-31)7-13-18(32)30-20(34)29-13/h3-4,7-9,11,27H,1-2,5-6H2,(H,25,33)(H2,29,30,32,34)/b13-7- QEWQNSGNUVFVJT-QPEQYQDCSA-N 219140 US9303033, K12, Table 23A, Compound 97 Casein kinase II subunit beta 1872 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219140 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219140&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314870 329994324 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384610 CC(C)(C)NC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H23N7O3S/c1-22(2,3)28-20(31)16-7-6-15(33-16)13-9-17(24-12-4-5-12)29-18(25-13)11(10-23-29)8-14-19(30)27-21(32)26-14/h6-10,12,24H,4-5H2,1-3H3,(H,28,31)(H2,26,27,30,32)/b14-8- VNAPKWGBJGYPOB-ZSOIEALJSA-N 219141 US9303033, L12, Table 23A, Compound 98 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219141&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314337 329994325 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384611 O=C(NC1CCNC1)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H22N8O3S/c31-20-15(28-22(33)29-20)7-11-9-24-30-18(25-12-1-2-12)8-14(27-19(11)30)16-3-4-17(34-16)21(32)26-13-5-6-23-10-13/h3-4,7-9,12-13,23,25H,1-2,5-6,10H2,(H,26,32)(H2,28,29,31,33)/b15-7- UYPRDHJWGXOSJZ-CHHVJCJISA-N 219142 US9303033, M12, Table 23A, Compound 99 Casein kinase II subunit beta 1260.4 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219142&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335955 329994326 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384612 FC1CCN(CC1)C(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H22FN7O3S/c24-13-5-7-30(8-6-13)22(33)18-4-3-17(35-18)15-10-19(26-14-1-2-14)31-20(27-15)12(11-25-31)9-16-21(32)29-23(34)28-16/h3-4,9-11,13-14,26H,1-2,5-8H2,(H2,28,29,32,34)/b16-9- DJOSHWBIKGHFMP-SXGWCWSVSA-N 219144 US9303033, O12, Table 23A, Compound 101 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219144&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335069 329994328 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384613 O=C(NC1CCC1)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H21N7O3S/c30-20-15(27-22(32)28-20)8-11-10-23-29-18(24-13-4-5-13)9-14(26-19(11)29)16-6-7-17(33-16)21(31)25-12-2-1-3-12/h6-10,12-13,24H,1-5H2,(H,25,31)(H2,27,28,30,32)/b15-8- XEQMCJIZVYSADU-NVNXTCNLSA-N 219145 US9303033, P12, Table 23A, Compound 102 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219145 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219145&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335886 329994329 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384614 O=C(NCc1cccnc1)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H20N8O3S/c33-22-17(30-24(35)31-22)8-14-12-27-32-20(28-15-3-4-15)9-16(29-21(14)32)18-5-6-19(36-18)23(34)26-11-13-2-1-7-25-10-13/h1-2,5-10,12,15,28H,3-4,11H2,(H,26,34)(H2,30,31,33,35)/b17-8- ZZZMTOOMLPNGQT-IUXPMGMMSA-N 219146 US9303033, Q12, Table 23A, Compound 103 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219146 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219146&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335960 329994330 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384615 CN(C)C1CCN(Cc2ccc(s2)-c2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)C1 InChI=1S/C24H28N8O2S/c1-30(2)16-7-8-31(12-16)13-17-5-6-20(35-17)18-10-21(26-15-3-4-15)32-22(27-18)14(11-25-32)9-19-23(33)29-24(34)28-19/h5-6,9-11,15-16,26H,3-4,7-8,12-13H2,1-2H3,(H2,28,29,33,34)/b19-9- PEWJTOALHQWCKX-OCKHKDLRSA-N 219147 US9303033, R12, Table 23A, Compound 104::US9303033, T13, Table 25A, Compound 2 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219147 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219147&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313920 329994331 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384616 CN1CCN(Cc2ccc(s2)-c2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)CC1 InChI=1S/C23H26N8O2S/c1-29-6-8-30(9-7-29)13-16-4-5-19(34-16)17-11-20(25-15-2-3-15)31-21(26-17)14(12-24-31)10-18-22(32)28-23(33)27-18/h4-5,10-12,15,25H,2-3,6-9,13H2,1H3,(H2,27,28,32,33)/b18-10- XQSZLZZHYPSMBY-ZDLGFXPLSA-N 219148 US9303033, S12, Table 23A, Compound 105::US9303033, U13, Table 25A, Compound 3 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219148 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219148&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314032 329994332 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384617 CN(C)C(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H19N7O3S/c1-26(2)19(29)15-6-5-14(31-15)12-8-16(22-11-3-4-11)27-17(23-12)10(9-21-27)7-13-18(28)25-20(30)24-13/h5-9,11,22H,3-4H2,1-2H3,(H2,24,25,28,30)/b13-7- LZYVCKNXTQVHHF-QPEQYQDCSA-N 219103 BDBM220100::US9303033, Z10, Table 23A, Compound 60 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219103 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219103&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314279 329994287 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384618 N[C@H]1CCN(C1)C(=O)c1cc(cs1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H22N8O3S/c23-13-3-4-29(9-13)21(32)17-6-12(10-34-17)15-7-18(25-14-1-2-14)30-19(26-15)11(8-24-30)5-16-20(31)28-22(33)27-16/h5-8,10,13-14,25H,1-4,9,23H2,(H2,27,28,31,33)/b16-5-/t13-/m0/s1 VOORUZPHJGXVFC-LDFHSBOYSA-N 219149 US9303033, U12, Table 23A, Compound 107 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219149 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219149&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335159 329994333 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384619 CC(=O)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H16N6O3S/c1-9(26)14-4-5-15(29-14)12-7-16(21-11-2-3-11)25-17(22-12)10(8-20-25)6-13-18(27)24-19(28)23-13/h4-8,11,21H,2-3H2,1H3,(H2,23,24,27,28)/b13-6- JBTYYLMJVMYAFT-MLPAPPSSSA-N 219154 US9303033, A13, Table 23A, Compound 113 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219154 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219154&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335263 329994338 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384620 O=C(N1CCC(C1)c1cccnc1)c1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C27H24N8O3S/c36-25-20(32-27(38)33-25)10-17-13-29-35-23(30-18-3-4-18)11-19(31-24(17)35)21-5-6-22(39-21)26(37)34-9-7-16(14-34)15-2-1-8-28-12-15/h1-2,5-6,8,10-13,16,18,30H,3-4,7,9,14H2,(H2,32,33,36,38)/b20-10- KNSXEUDNKYALNB-JMIUGGIZSA-N 219155 US9303033, B13, Table 23A, Compound 114 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219155&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335746 329994339 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384621 OC(=O)c1cc(cs1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H14N6O4S/c25-16-12(22-18(28)23-16)3-8-6-19-24-14(20-10-1-2-10)5-11(21-15(8)24)9-4-13(17(26)27)29-7-9/h3-7,10,20H,1-2H2,(H,26,27)(H2,22,23,25,28)/b12-3- GFWWFIFCBKHNTL-BASWHVEKSA-N 219156 US9303033, C13, Table 24A, Compound 1 Casein kinase II subunit beta 2382 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219156 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219156&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314629 329994340 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384622 CN(C)C(=O)c1cc(cs1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H19N7O3S/c1-26(2)19(29)15-6-11(9-31-15)13-7-16(22-12-3-4-12)27-17(23-13)10(8-21-27)5-14-18(28)25-20(30)24-14/h5-9,12,22H,3-4H2,1-2H3,(H2,24,25,28,30)/b14-5- RTNMQKXKAVOFRY-RZNTYIFUSA-N 219157 US9303033, D13, Table 24A, Compound 2::US9303033, N13, Table 24A, Compound 12 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219157 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219157&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335294 329994341 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384623 O=C(NCCN1CCCC1)c1cc(cs1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H26N8O3S/c33-22-18(29-24(35)30-22)9-14-12-26-32-20(27-16-3-4-16)11-17(28-21(14)32)15-10-19(36-13-15)23(34)25-5-8-31-6-1-2-7-31/h9-13,16,27H,1-8H2,(H,25,34)(H2,29,30,33,35)/b18-9- CMQRGXXLQXTARR-NVMNQCDNSA-N 219158 US9303033, E13, Table 24A, Compound 3 Casein kinase II subunit beta 982 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219158&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335896 329994342 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384624 N[C@@H]1CCN(C1)C(=O)c1cc(cs1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H22N8O3S/c23-13-3-4-29(9-13)21(32)17-6-12(10-34-17)15-7-18(25-14-1-2-14)30-19(26-15)11(8-24-30)5-16-20(31)28-22(33)27-16/h5-8,10,13-14,25H,1-4,9,23H2,(H2,27,28,31,33)/b16-5-/t13-/m1/s1 VOORUZPHJGXVFC-VLLAWNLXSA-N 219159 US9303033, F13, Table 24A, Compound 4 Casein kinase II subunit beta 608.4 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219159 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219159&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335748 329994343 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384625 C[C@H]1CN(C[C@@H](C)N1)C(=O)c1cc(cs1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H26N8O3S/c1-12-9-31(10-13(2)26-12)23(34)19-6-15(11-36-19)17-7-20(27-16-3-4-16)32-21(28-17)14(8-25-32)5-18-22(33)30-24(35)29-18/h5-8,11-13,16,26-27H,3-4,9-10H2,1-2H3,(H2,29,30,33,35)/b18-5-/t12-,13+ LMOXZOGZDIXIFY-HYTJYWDVSA-N 219160 US9303033, G13, Table 24A, Compound 5 Casein kinase II subunit beta 888 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219160 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219160&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335558 329994344 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384626 CN1CCCC1CCNC(=O)c1cc(cs1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C25H28N8O3S/c1-32-8-2-3-17(32)6-7-26-24(35)20-10-15(13-37-20)18-11-21(28-16-4-5-16)33-22(29-18)14(12-27-33)9-19-23(34)31-25(36)30-19/h9-13,16-17,28H,2-8H2,1H3,(H,26,35)(H2,30,31,34,36)/b19-9- MXCSLCGRMKRTEN-OCKHKDLRSA-N 219161 US9303033, H13, Table 24A, Compound 6 Casein kinase II subunit beta 654 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219161 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219161&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335090 329994345 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384627 CN(C)CCCNC(=O)c1cc(cs1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H26N8O3S/c1-30(2)7-3-6-24-22(33)18-9-14(12-35-18)16-10-19(26-15-4-5-15)31-20(27-16)13(11-25-31)8-17-21(32)29-23(34)28-17/h8-12,15,26H,3-7H2,1-2H3,(H,24,33)(H2,28,29,32,34)/b17-8- ZVYVHWPZOWRWME-IUXPMGMMSA-N 219162 US9303033, I13, Table 24A, Compound 7 Casein kinase II subunit beta 1878.1 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219162 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219162&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335556 329994346 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384628 O=C(NC1CC1)c1cc(cs1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H19N7O3S/c29-19-15(26-21(31)27-19)5-10-8-22-28-17(23-12-1-2-12)7-14(25-18(10)28)11-6-16(32-9-11)20(30)24-13-3-4-13/h5-9,12-13,23H,1-4H2,(H,24,30)(H2,26,27,29,31)/b15-5- ORQKZLDHHYFHTB-WCSRMQSCSA-N 219163 US9303033, J13, Table 24A, Compound 8 Casein kinase II subunit beta 548 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219163 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219163&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335302 329994347 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384629 COC(=O)c1cc(cs1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H16N6O4S/c1-29-18(27)14-5-10(8-30-14)12-6-15(21-11-2-3-11)25-16(22-12)9(7-20-25)4-13-17(26)24-19(28)23-13/h4-8,11,21H,2-3H2,1H3,(H2,23,24,26,28)/b13-4- SLLVDJSAZPYOAV-PQMHYQBVSA-N 219164 US9303033, K13, Table 24A, Compound 9 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219164 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219164&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335979 329994348 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384630 CN1CCC(CC1)NC(=O)c1cc(cs1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H26N8O3S/c1-31-6-4-16(5-7-31)27-23(34)19-9-14(12-36-19)17-10-20(26-15-2-3-15)32-21(28-17)13(11-25-32)8-18-22(33)30-24(35)29-18/h8-12,15-16,26H,2-7H2,1H3,(H,27,34)(H2,29,30,33,35)/b18-8- LMARXBUIMCNMMM-LSCVHKIXSA-N 219165 US9303033, L13, Table 24A, Compound 10 Casein kinase II subunit beta 1954.7 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219165 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219165&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335973 329994349 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384631 O=C(NC1CCNC1)c1cc(cs1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H22N8O3S/c31-20-16(28-22(33)29-20)5-11-8-24-30-18(25-13-1-2-13)7-15(27-19(11)30)12-6-17(34-10-12)21(32)26-14-3-4-23-9-14/h5-8,10,13-14,23,25H,1-4,9H2,(H,26,32)(H2,28,29,31,33)/b16-5- STZPHMNNSSVFEV-BNCCVWRVSA-N 219166 US9303033, M13, Table 24A, Compound 11 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219166 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219166&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335557 329994350 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384632 CN(C)C(=O)c1cc(cs1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H19N7O3S/c1-26(2)19(29)15-6-11(9-31-15)13-7-16(22-12-3-4-12)27-17(23-13)10(8-21-27)5-14-18(28)25-20(30)24-14/h5-9,12,22H,3-4H2,1-2H3,(H2,24,25,28,30)/b14-5- RTNMQKXKAVOFRY-RZNTYIFUSA-N 219157 US9303033, D13, Table 24A, Compound 2::US9303033, N13, Table 24A, Compound 12 Casein kinase II subunit beta 1984.8 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219157 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219157&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335294 329994341 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384633 CCC(CN1CCCC1)NC(=O)c1cc(cs1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C26H30N8O3S/c1-2-17(13-33-7-3-4-8-33)29-25(36)21-10-16(14-38-21)19-11-22(28-18-5-6-18)34-23(30-19)15(12-27-34)9-20-24(35)32-26(37)31-20/h9-12,14,17-18,28H,2-8,13H2,1H3,(H,29,36)(H2,31,32,35,37)/b20-9- CJZZCHXXFUEYAA-UKWGHVSLSA-N 219167 US9303033, O13, Table 24A, Compound 13 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219167 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219167&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335744 329994351 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384634 CN(C)CC(C)(C)CNC(=O)c1cc(cs1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C25H30N8O3S/c1-25(2,13-32(3)4)12-26-23(35)19-8-15(11-37-19)17-9-20(28-16-5-6-16)33-21(29-17)14(10-27-33)7-18-22(34)31-24(36)30-18/h7-11,16,28H,5-6,12-13H2,1-4H3,(H,26,35)(H2,30,31,34,36)/b18-7- GXLUJHJUZOJGHB-WSVATBPTSA-N 219168 US9303033, P13, Table 24A, Compound 14 Casein kinase II subunit beta 813.3 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219168 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219168&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335290 329994352 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384635 CC1CN(CC(C)O1)C(=O)c1cc(cs1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H25N7O4S/c1-12-9-30(10-13(2)35-12)23(33)19-6-15(11-36-19)17-7-20(26-16-3-4-16)31-21(27-17)14(8-25-31)5-18-22(32)29-24(34)28-18/h5-8,11-13,16,26H,3-4,9-10H2,1-2H3,(H2,28,29,32,34)/b18-5- JVJGOTUNBIUJDT-DVZOWYKESA-N 219170 US9303033, R13, Table 24A, Compound 16 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219170 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219170&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314040 329994354 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384636 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(nc12)-c1ccc(CN2CCOCC2)s1 InChI=1S/C22H23N7O3S/c30-21-17(26-22(31)27-21)9-13-11-23-29-19(24-14-1-2-14)10-16(25-20(13)29)18-4-3-15(33-18)12-28-5-7-32-8-6-28/h3-4,9-11,14,24H,1-2,5-8,12H2,(H2,26,27,30,31)/b17-9- OYOCDZLFPKERPX-MFOYZWKCSA-N 219137 US9303033, H12, Table 23A, Compound 94::US9303033, S13, Table 25A, Compound 1 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219137 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219137&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314341 329994321 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384637 CN(C)C1CCN(Cc2ccc(s2)-c2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)C1 InChI=1S/C24H28N8O2S/c1-30(2)16-7-8-31(12-16)13-17-5-6-20(35-17)18-10-21(26-15-3-4-15)32-22(27-18)14(11-25-32)9-19-23(33)29-24(34)28-19/h5-6,9-11,15-16,26H,3-4,7-8,12-13H2,1-2H3,(H2,28,29,33,34)/b19-9- PEWJTOALHQWCKX-OCKHKDLRSA-N 219147 US9303033, R12, Table 23A, Compound 104::US9303033, T13, Table 25A, Compound 2 Casein kinase II subunit beta 810.6 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219147 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219147&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313920 329994331 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384638 CN1CCN(Cc2ccc(s2)-c2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)CC1 InChI=1S/C23H26N8O2S/c1-29-6-8-30(9-7-29)13-16-4-5-19(34-16)17-11-20(25-15-2-3-15)31-21(26-17)14(12-24-31)10-18-22(32)28-23(33)27-18/h4-5,10-12,15,25H,2-3,6-9,13H2,1H3,(H2,27,28,32,33)/b18-10- XQSZLZZHYPSMBY-ZDLGFXPLSA-N 219148 US9303033, S12, Table 23A, Compound 105::US9303033, U13, Table 25A, Compound 3 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219148 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219148&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314032 329994332 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384639 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(nc12)-c1ccc(CN2CCCC2)s1 InChI=1S/C22H23N7O2S/c30-21-17(26-22(31)27-21)9-13-11-23-29-19(24-14-3-4-14)10-16(25-20(13)29)18-6-5-15(32-18)12-28-7-1-2-8-28/h5-6,9-11,14,24H,1-4,7-8,12H2,(H2,26,27,30,31)/b17-9- LZVIBBOQQBOWBO-MFOYZWKCSA-N 219174 US9303033, V13, Table 25A, Compound 4 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219174 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219174&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315032 329994355 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384640 CC1CN(Cc2ccc(s2)-c2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)CC(C)O1 InChI=1S/C24H27N7O3S/c1-13-10-30(11-14(2)34-13)12-17-5-6-20(35-17)18-8-21(26-16-3-4-16)31-22(27-18)15(9-25-31)7-19-23(32)29-24(33)28-19/h5-9,13-14,16,26H,3-4,10-12H2,1-2H3,(H2,28,29,32,33)/b19-7- NNKDGVZPZWFZTD-GXHLCREISA-N 219091 US9303033, N10, Table 23A, Compound 48::US9303033, W13, Table 25A, Compound 5 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219091&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314703 329994275 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384641 COCCNCc1ccc(s1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H23N7O3S/c1-31-7-6-22-11-14-4-5-17(32-14)15-9-18(24-13-2-3-13)28-19(25-15)12(10-23-28)8-16-20(29)27-21(30)26-16/h4-5,8-10,13,22,24H,2-3,6-7,11H2,1H3,(H2,26,27,29,30)/b16-8- LQFKGIDZLUYTQQ-PXNMLYILSA-N 219092 US9303033, O10, Table 23A, Compound 49::US9303033, X13, Table 25A, Compound 6 Casein kinase II subunit beta 1872 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219092&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314643 329994276 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384642 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(nc12)-c1csc(CN2CCCC2)c1 InChI=1S/C22H23N7O2S/c30-21-18(26-22(31)27-21)8-13-10-23-29-19(24-15-3-4-15)9-17(25-20(13)29)14-7-16(32-12-14)11-28-5-1-2-6-28/h7-10,12,15,24H,1-6,11H2,(H2,26,27,30,31)/b18-8- ABNNIWMSPODMFK-LSCVHKIXSA-N 219177 US9303033, Y13, Table 26A, Compound 1 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219177 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219177&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313761 329994356 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384643 CN(C)C1CCN(Cc2cc(cs2)-c2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)C1 InChI=1S/C24H28N8O2S/c1-30(2)17-5-6-31(11-17)12-18-7-15(13-35-18)19-9-21(26-16-3-4-16)32-22(27-19)14(10-25-32)8-20-23(33)29-24(34)28-20/h7-10,13,16-17,26H,3-6,11-12H2,1-2H3,(H2,28,29,33,34)/b20-8- KYFVFBPUOVBQRB-ZBKNUEDVSA-N 219178 US9303033, Z13, Table 26A, Compound 2 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219178 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219178&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335752 329994357 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384644 CC1CN(Cc2cc(cs2)-c2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)CC(C)O1 InChI=1S/C24H27N7O3S/c1-13-9-30(10-14(2)34-13)11-18-5-16(12-35-18)19-7-21(26-17-3-4-17)31-22(27-19)15(8-25-31)6-20-23(32)29-24(33)28-20/h5-8,12-14,17,26H,3-4,9-11H2,1-2H3,(H2,28,29,32,33)/b20-6- JKWVBGAQCKBZDK-IOXNKQMXSA-N 219179 US9303033, A14, Table 26A, Compound 3 Casein kinase II subunit beta 1572.2 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219179 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219179&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335107 329994358 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384645 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(nc12)-c1csc(CNC2CCCC2)c1 InChI=1S/C23H25N7O2S/c31-22-19(28-23(32)29-22)8-13-10-25-30-20(26-16-5-6-16)9-18(27-21(13)30)14-7-17(33-12-14)11-24-15-3-1-2-4-15/h7-10,12,15-16,24,26H,1-6,11H2,(H2,28,29,31,32)/b19-8- SWYZKMDPKXGAIK-UWVJOHFNSA-N 219180 US9303033, B14, Table 26A, Compound 4 Casein kinase II subunit beta 1445.1 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219180 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219180&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335273 329994359 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384646 CC(C)(C)OC(=O)N(C1CC1)C1=NC(=C[N]2=C(\C=C3/NC(=O)NC3=O)C=NC12)c1cccc(OC(F)(F)F)c1 InChI=1S/C25H24F3N6O5/c1-24(2,3)39-23(37)34(14-7-8-14)20-19-29-11-15(10-17-21(35)32-22(36)31-17)33(19)12-18(30-20)13-5-4-6-16(9-13)38-25(26,27)28/h4-6,9-12,14,19H,7-8H2,1-3H3,(H2,31,32,35,36)/b17-10- DSJZSUSIFFVRIN-YVLHZVERSA-N 219181 US9303033, C14, Table 28A, Compound 1 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219181&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 124222762 329994360 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384647 O=C1NC(=O)\C(N1)=C\C1=[N]2C=C(N=C(NC3CC3)C2N=C1)C#Cc1ccccc1 InChI=1S/C21H17N6O2/c28-20-17(25-21(29)26-20)10-16-11-22-19-18(23-14-8-9-14)24-15(12-27(16)19)7-6-13-4-2-1-3-5-13/h1-5,10-12,14,19H,8-9H2,(H,23,24)(H2,25,26,28,29)/b17-10- OURLHKDASRDKGD-YVLHZVERSA-N 219182 US9303033, D14, Table 28A, Compound 2 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219182 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219182&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 124222763 329994361 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384648 O=C1NC(=O)\C(N1)=C\C1=[N]2C=C(N=C(NC3CC3)C2N=C1)c1cccc(CN2CCOCC2)c1 InChI=1S/C24H26N7O3/c32-23-19(28-24(33)29-23)11-18-12-25-22-21(26-17-4-5-17)27-20(14-31(18)22)16-3-1-2-15(10-16)13-30-6-8-34-9-7-30/h1-3,10-12,14,17,22H,4-9,13H2,(H,26,27)(H2,28,29,32,33)/b19-11- MMJSGQUMSXZSHG-ODLFYWEKSA-N 219183 US9303033, E14, Table 28A, Compound 3 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219183 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219183&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 124222765 329994362 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384649 FC(F)(F)Oc1cccc(c1)C1=C[N]2=C(\C=C3/NC(=O)NC3=O)C=NC2C(NC2CC2)=N1 InChI=1S/C20H16F3N6O3/c21-20(22,23)32-13-3-1-2-10(6-13)15-9-29-12(7-14-18(30)28-19(31)27-14)8-24-17(29)16(26-15)25-11-4-5-11/h1-3,6-9,11,17H,4-5H2,(H,25,26)(H2,27,28,30,31)/b14-7- DVEWWXNGYAALSZ-AUWJEWJLSA-N 219184 US9303033, F14, Table 28A, Compound 4 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219184 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219184&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 124222767 329994363 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384650 Fc1cccc(c1)C1=C[N]2=C(\C=C3/NC(=O)NC3=O)C=NC2C(NC2CC2)=N1 InChI=1S/C19H16FN6O2/c20-11-3-1-2-10(6-11)15-9-26-13(7-14-18(27)25-19(28)24-14)8-21-17(26)16(23-15)22-12-4-5-12/h1-3,6-9,12,17H,4-5H2,(H,22,23)(H2,24,25,27,28)/b14-7- XQPOAEZCVFTPLU-AUWJEWJLSA-N 219185 US9303033, G14, Table 28A, Compound 5 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219185 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219185&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 124222769 329994364 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384651 CSc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C13H13N7O2S/c1-23-13-17-9-6(4-8-10(21)18-12(22)16-8)5-14-20(9)11(19-13)15-7-2-3-7/h4-5,7H,2-3H2,1H3,(H,15,17,19)(H2,16,18,21,22)/b8-4- YYYJAQABQGZRDC-YWEYNIOJSA-N 219186 US9303033, H14, Table 33A, Compound 1 Casein kinase II subunit beta 1306.4 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219186 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219186&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314017 329994365 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384652 CS(=O)(=O)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C13H13N7O4S/c1-25(23,24)13-17-9-6(4-8-10(21)18-12(22)16-8)5-14-20(9)11(19-13)15-7-2-3-7/h4-5,7H,2-3H2,1H3,(H,15,17,19)(H2,16,18,21,22)/b8-4- CPSKTKODASUTHS-YWEYNIOJSA-N 219187 US9303033, I14, Table 33A, Compound 2 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219187 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219187&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313878 329994366 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384653 Clc1cccc(Nc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C18H15ClN8O2/c19-10-2-1-3-12(7-10)21-16-24-14-9(6-13-15(28)25-18(29)23-13)8-20-27(14)17(26-16)22-11-4-5-11/h1-3,6-8,11H,4-5H2,(H2,21,22,24,26)(H2,23,25,28,29)/b13-6- UVBVBKKAPHZRDS-MLPAPPSSSA-N 219188 US9303033, J14, Table 33A, Compound 3 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219188 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219188&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67253675 329994367 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384654 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)N1CCCCC1 InChI=1S/C17H20N8O2/c26-14-12(20-17(27)22-14)8-10-9-18-25-13(10)21-15(24-6-2-1-3-7-24)23-16(25)19-11-4-5-11/h8-9,11H,1-7H2,(H,19,21,23)(H2,20,22,26,27)/b12-8- KOMAAJVFZAVJTA-WQLSENKSSA-N 219189 US9303033, K14, Table 33A, Compound 4 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219189 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219189&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335765 329994368 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384655 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(Nc3cccc(c3)C#C)nc12 InChI=1S/C20H16N8O2/c1-2-11-4-3-5-14(8-11)22-18-25-16-12(9-15-17(29)26-20(30)24-15)10-21-28(16)19(27-18)23-13-6-7-13/h1,3-5,8-10,13H,6-7H2,(H2,22,23,25,27)(H2,24,26,29,30)/b15-9- KJPIJDUWFVHSIB-DHDCSXOGSA-N 219190 US9303033, L14, Table 33A, Compound 5 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219190&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 91870040 329994369 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384656 Fc1cccc(Nc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C18H15FN8O2/c19-10-2-1-3-12(7-10)21-16-24-14-9(6-13-15(28)25-18(29)23-13)8-20-27(14)17(26-16)22-11-4-5-11/h1-3,6-8,11H,4-5H2,(H2,21,22,24,26)(H2,23,25,28,29)/b13-6- CQHHICGIFKDHJB-MLPAPPSSSA-N 219191 US9303033, M14, Table 33A, Compound 6 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219191&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335562 329994370 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384657 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(Nc3cccc(CN4CCCC4)c3)nc12 InChI=1S/C23H25N9O2/c33-20-18(27-23(34)29-20)11-15-12-24-32-19(15)28-21(30-22(32)26-16-6-7-16)25-17-5-3-4-14(10-17)13-31-8-1-2-9-31/h3-5,10-12,16H,1-2,6-9,13H2,(H2,25,26,28,30)(H2,27,29,33,34)/b18-11- MBPXROOMQQWLDH-WQRHYEAKSA-N 219192 US9303033, N14, Table 33A, Compound 7 Casein kinase II subunit beta 2334.4 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219192 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219192&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335563 329994371 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384658 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(Nc3cccc(OCCN4CCOCC4)c3)nc12 InChI=1S/C24H27N9O4/c34-21-19(28-24(35)30-21)12-15-14-25-33-20(15)29-22(31-23(33)27-16-4-5-16)26-17-2-1-3-18(13-17)37-11-8-32-6-9-36-10-7-32/h1-3,12-14,16H,4-11H2,(H2,26,27,29,31)(H2,28,30,34,35)/b19-12- CNTLAUZQSDMHHW-UNOMPAQXSA-N 219193 US9303033, O14, Table 33A, Compound 8 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219193 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219193&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335925 329994372 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384659 Fc1ccc(Nc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C18H15FN8O2/c19-10-1-3-11(4-2-10)21-16-24-14-9(7-13-15(28)25-18(29)23-13)8-20-27(14)17(26-16)22-12-5-6-12/h1-4,7-8,12H,5-6H2,(H2,21,22,24,26)(H2,23,25,28,29)/b13-7- HZTPULGMJHSDKT-QPEQYQDCSA-N 219194 US9303033, P14, Table 33A, Compound 9 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219194 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219194&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335118 329994373 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384660 COc1cccc(Nc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C19H18N8O3/c1-30-13-4-2-3-12(8-13)21-17-24-15-10(7-14-16(28)25-19(29)23-14)9-20-27(15)18(26-17)22-11-5-6-11/h2-4,7-9,11H,5-6H2,1H3,(H2,21,22,24,26)(H2,23,25,28,29)/b14-7- RIZYNJYFKDKGCK-AUWJEWJLSA-N 219195 US9303033, Q14, Table 33A, Compound 10 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219195&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335120 329994374 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384661 NCc1ccc(Nc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C19H19N9O2/c20-8-10-1-3-12(4-2-10)22-17-25-15-11(7-14-16(29)26-19(30)24-14)9-21-28(15)18(27-17)23-13-5-6-13/h1-4,7,9,13H,5-6,8,20H2,(H2,22,23,25,27)(H2,24,26,29,30)/b14-7- DRBZACNQFZSQSK-AUWJEWJLSA-N 219196 US9303033, R14, Table 33A, Compound 11 Casein kinase II subunit beta 2405.8 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219196 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219196&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335568 329994375 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384662 OCCCNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C15H18N8O3/c24-5-1-4-16-13-20-11-8(6-10-12(25)21-15(26)19-10)7-17-23(11)14(22-13)18-9-2-3-9/h6-7,9,24H,1-5H2,(H2,16,18,20,22)(H2,19,21,25,26)/b10-6- FNPYBHPXZUCQCB-POHAHGRESA-N 219197 US9303033, S14, Table 33A, Compound 12 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219197 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219197&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335306 329994376 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384663 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)N1CCOCC1 InChI=1S/C16H18N8O3/c25-13-11(19-16(26)21-13)7-9-8-17-24-12(9)20-14(23-3-5-27-6-4-23)22-15(24)18-10-1-2-10/h7-8,10H,1-6H2,(H,18,20,22)(H2,19,21,25,26)/b11-7- BCSSNDOQQFOGIB-XFFZJAGNSA-N 219198 US9303033, T14, Table 33A, Compound 13 Casein kinase II subunit beta 1250 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219198 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219198&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335569 329994377 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384664 OCCNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C14H16N8O3/c23-4-3-15-12-19-10-7(5-9-11(24)20-14(25)18-9)6-16-22(10)13(21-12)17-8-1-2-8/h5-6,8,23H,1-4H2,(H2,15,17,19,21)(H2,18,20,24,25)/b9-5- CWXHZSFXGZPZHC-UITAMQMPSA-N 219199 US9303033, U14, Table 33A, Compound 14 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219199 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219199&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335927 329994378 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384665 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCCN3CCCC3)nc12 InChI=1S/C18H23N9O2/c28-15-13(22-18(29)24-15)9-11-10-20-27-14(11)23-16(25-17(27)21-12-3-4-12)19-5-8-26-6-1-2-7-26/h9-10,12H,1-8H2,(H2,19,21,23,25)(H2,22,24,28,29)/b13-9- ZZINTIMGPBCZKI-LCYFTJDESA-N 219200 US9303033, V14, Table 33A, Compound 15 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219200 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219200&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335299 329994379 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384666 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NC3CCC3)nc12 InChI=1S/C16H18N8O2/c25-13-11(20-16(26)22-13)6-8-7-17-24-12(8)21-14(18-9-2-1-3-9)23-15(24)19-10-4-5-10/h6-7,9-10H,1-5H2,(H2,18,19,21,23)(H2,20,22,25,26)/b11-6- PXESDFZJQUEDKK-WDZFZDKYSA-N 219201 US9303033, W14, Table 33A, Compound 16 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219201 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219201&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336004 329994380 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384667 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NC3CCCC3)nc12 InChI=1S/C17H20N8O2/c26-14-12(21-17(27)23-14)7-9-8-18-25-13(9)22-15(19-10-3-1-2-4-10)24-16(25)20-11-5-6-11/h7-8,10-11H,1-6H2,(H2,19,20,22,24)(H2,21,23,26,27)/b12-7- IZBKEGVKHFRFNP-GHXNOFRVSA-N 219202 US9303033, X14, Table 33A, Compound 17 Casein kinase II subunit beta 1120.5 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219202 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219202&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335279 329994381 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384668 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NN3CCOCC3)nc12 InChI=1S/C16H19N9O3/c26-13-11(19-16(27)21-13)7-9-8-17-25-12(9)20-14(22-15(25)18-10-1-2-10)23-24-3-5-28-6-4-24/h7-8,10H,1-6H2,(H2,18,20,22,23)(H2,19,21,26,27)/b11-7- MXMWGINWJJCNJQ-XFFZJAGNSA-N 219203 US9303033, Y14, Table 33A, Compound 18 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219203 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219203&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89888231 329994382 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384669 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCC3CC3)nc12 InChI=1S/C16H18N8O2/c25-13-11(20-16(26)22-13)5-9-7-18-24-12(9)21-14(17-6-8-1-2-8)23-15(24)19-10-3-4-10/h5,7-8,10H,1-4,6H2,(H2,17,19,21,23)(H2,20,22,25,26)/b11-5- GOCSFUSQHIBANS-WZUFQYTHSA-N 219204 US9303033, A15, Table 33A, Compound 20 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219204 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219204&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67254069 329994383 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384670 FC(F)(F)CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C14H13F3N8O2/c15-14(16,17)5-18-11-22-9-6(3-8-10(26)23-13(27)21-8)4-19-25(9)12(24-11)20-7-1-2-7/h3-4,7H,1-2,5H2,(H2,18,20,22,24)(H2,21,23,26,27)/b8-3- CEZWMSIKAYINNL-BAQGIRSFSA-N 219205 US9303033, B15, Table 33A, Compound 21 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219205 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219205&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335143 329994384 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384671 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NC3CC3)nc12 InChI=1S/C15H16N8O2/c24-12-10(19-15(25)21-12)5-7-6-16-23-11(7)20-13(17-8-1-2-8)22-14(23)18-9-3-4-9/h5-6,8-9H,1-4H2,(H2,17,18,20,22)(H2,19,21,24,25)/b10-5- LLDORLDDEDCSIN-YHYXMXQVSA-N 219206 US9303033, C15, Table 33A, Compound 22 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219206 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219206&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335142 329994385 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384672 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCCCN3CCOCC3)nc12 InChI=1S/C19H25N9O3/c29-16-14(23-19(30)25-16)10-12-11-21-28-15(12)24-17(26-18(28)22-13-2-3-13)20-4-1-5-27-6-8-31-9-7-27/h10-11,13H,1-9H2,(H2,20,22,24,26)(H2,23,25,29,30)/b14-10- SNLSPSNOPDQAMY-UVTDQMKNSA-N 219207 US9303033, D15, Table 33A, Compound 23 Casein kinase II subunit beta 1546.4 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219207 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219207&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335301 329994386 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384673 CN(C)CC(C)(C)CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H27N9O2/c1-19(2,10-27(3)4)9-20-16-24-14-11(7-13-15(29)25-18(30)23-13)8-21-28(14)17(26-16)22-12-5-6-12/h7-8,12H,5-6,9-10H2,1-4H3,(H2,20,22,24,26)(H2,23,25,29,30)/b13-7- QCDPUXOLRHLVKX-QPEQYQDCSA-N 219208 US9303033, E15, Table 33A, Compound 24 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219208 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219208&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335144 329994387 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384674 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)N1CCCC1 InChI=1S/C16H18N8O2/c25-13-11(19-16(26)21-13)7-9-8-17-24-12(9)20-14(23-5-1-2-6-23)22-15(24)18-10-3-4-10/h7-8,10H,1-6H2,(H,18,20,22)(H2,19,21,25,26)/b11-7- ZSMDNUZIWPSKPU-XFFZJAGNSA-N 219209 US9303033, F15, Table 33A, Compound 25 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219209 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219209&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335932 329994388 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384675 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3cccnc3)nc12 InChI=1S/C18H17N9O2/c28-15-13(23-18(29)25-15)6-11-9-21-27-14(11)24-16(26-17(27)22-12-3-4-12)20-8-10-2-1-5-19-7-10/h1-2,5-7,9,12H,3-4,8H2,(H2,20,22,24,26)(H2,23,25,28,29)/b13-6- HJRIHHKAYNYRCZ-MLPAPPSSSA-N 219210 US9303033, G15, Table 33A, Compound 26 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219210 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219210&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335928 329994389 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384676 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3ccncc3)nc12 InChI=1S/C18H17N9O2/c28-15-13(23-18(29)25-15)7-11-9-21-27-14(11)24-16(26-17(27)22-12-1-2-12)20-8-10-3-5-19-6-4-10/h3-7,9,12H,1-2,8H2,(H2,20,22,24,26)(H2,23,25,28,29)/b13-7- GYQJZVHLDFAHIP-QPEQYQDCSA-N 219211 US9303033, H15, Table 33A, Compound 27 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219211 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219211&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335119 329994390 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384677 F[C@@H]1CCN(C1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C16H17FN8O2/c17-9-3-4-24(7-9)14-21-12-8(5-11-13(26)22-16(27)20-11)6-18-25(12)15(23-14)19-10-1-2-10/h5-6,9-10H,1-4,7H2,(H,19,21,23)(H2,20,22,26,27)/b11-5-/t9-/m1/s1 LNHMPILLPYVHKV-QQCYMQAYSA-N 219212 US9303033, I15, Table 33A, Compound 28 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219212&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335575 329994391 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384678 F[C@H]1CCN(C1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C16H17FN8O2/c17-9-3-4-24(7-9)14-21-12-8(5-11-13(26)22-16(27)20-11)6-18-25(12)15(23-14)19-10-1-2-10/h5-6,9-10H,1-4,7H2,(H,19,21,23)(H2,20,22,26,27)/b11-5-/t9-/m0/s1 LNHMPILLPYVHKV-BVBCSLMJSA-N 219213 US9303033, J15, Table 33A, Compound 29 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219213&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335762 329994392 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384679 FC(F)(F)CCNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C15H15F3N8O2/c16-15(17,18)3-4-19-12-23-10-7(5-9-11(27)24-14(28)22-9)6-20-26(10)13(25-12)21-8-1-2-8/h5-6,8H,1-4H2,(H2,19,21,23,25)(H2,22,24,27,28)/b9-5- BIJKIQJJUBOZAW-UITAMQMPSA-N 219214 US9303033, K15, Table 33A, Compound 30 Casein kinase II subunit beta 1655.8 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219214 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219214&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335931 329994393 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384680 CC(C)[C@H](CO)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C17H22N8O3/c1-8(2)12(7-26)20-15-22-13-9(5-11-14(27)23-17(28)21-11)6-18-25(13)16(24-15)19-10-3-4-10/h5-6,8,10,12,26H,3-4,7H2,1-2H3,(H2,19,20,22,24)(H2,21,23,27,28)/b11-5-/t12-/m0/s1 HNLWIKHHFDCBNN-QJGQKNTRSA-N 219215 US9303033, L15, Table 33A, Compound 31 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219215 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219215&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335571 329994394 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384681 CCOCCNc1nc(Nc2cccc(c2)C(F)(F)F)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C20H19F3N8O3/c1-2-34-7-6-24-18-30-17(26-13-5-3-4-12(9-13)20(21,22)23)28-15-11(10-25-31(15)18)8-14-16(32)29-19(33)27-14/h3-5,8-10H,2,6-7H2,1H3,(H2,24,26,28,30)(H2,27,29,32,33)/b14-8- MQKMNERYEDQRSA-ZSOIEALJSA-N 219216 US9303033, M15, Table 33A, Compound 32 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219216 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219216&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335771 329994395 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384682 CCOCCNc1nc(Nc2cccc(OC(F)(F)F)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C20H19F3N8O4/c1-2-34-7-6-24-18-30-17(26-12-4-3-5-13(9-12)35-20(21,22)23)28-15-11(10-25-31(15)18)8-14-16(32)29-19(33)27-14/h3-5,8-10H,2,6-7H2,1H3,(H2,24,26,28,30)(H2,27,29,32,33)/b14-8- MYPVDTRKUYGBQG-ZSOIEALJSA-N 219217 US9303033, N15, Table 33A, Compound 33 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219217 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219217&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335993 329994396 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384683 CCOCCNc1nc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C19H19ClN8O3/c1-2-31-7-6-21-18-27-17(23-13-5-3-4-12(20)9-13)25-15-11(10-22-28(15)18)8-14-16(29)26-19(30)24-14/h3-5,8-10H,2,6-7H2,1H3,(H2,21,23,25,27)(H2,24,26,29,30)/b14-8- DLJCBTHMMVXPHE-ZSOIEALJSA-N 219218 US9303033, O15, Table 33A, Compound 34 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219218 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219218&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335934 329994397 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384684 CCOCCNc1nc(Nc2ccc(F)c(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C19H18ClFN8O3/c1-2-32-6-5-22-18-28-17(24-11-3-4-13(21)12(20)8-11)26-15-10(9-23-29(15)18)7-14-16(30)27-19(31)25-14/h3-4,7-9H,2,5-6H2,1H3,(H2,22,24,26,28)(H2,25,27,30,31)/b14-7- OGFDVDKDSMUICW-AUWJEWJLSA-N 219219 US9303033, P15, Table 33A, Compound 35 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219219 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219219&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335770 329994398 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384685 CCOCCNc1nc(Nc2ccc(cc2)N2CCN(C)CC2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C24H30N10O3/c1-3-37-13-8-25-23-31-22(27-17-4-6-18(7-5-17)33-11-9-32(2)10-12-33)29-20-16(15-26-34(20)23)14-19-21(35)30-24(36)28-19/h4-7,14-15H,3,8-13H2,1-2H3,(H2,25,27,29,31)(H2,28,30,35,36)/b19-14- MKDAJHHESTYDDK-RGEXLXHISA-N 219220 US9303033, Q15, Table 33A, Compound 36 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219220 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219220&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335577 329994399 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384686 CCOCCNc1nc(Nc2cccc(OCCN3CCOCC3)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C25H31N9O5/c1-2-37-10-6-26-24-32-23(30-21-17(16-27-34(21)24)14-20-22(35)31-25(36)29-20)28-18-4-3-5-19(15-18)39-13-9-33-7-11-38-12-8-33/h3-5,14-16H,2,6-13H2,1H3,(H2,26,28,30,32)(H2,29,31,35,36)/b20-14- UGYGNIZRTNPUOF-ZHZULCJRSA-N 219221 US9303033, R15, Table 33A, Compound 37 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219221 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219221&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335990 329994400 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384687 CCOCCNc1nc(Nc2cccc(OC(C)C)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C22H26N8O4/c1-4-33-9-8-23-21-29-20(25-15-6-5-7-16(11-15)34-13(2)3)27-18-14(12-24-30(18)21)10-17-19(31)28-22(32)26-17/h5-7,10-13H,4,8-9H2,1-3H3,(H2,23,25,27,29)(H2,26,28,31,32)/b17-10- HAPFXPCFNFJHQB-YVLHZVERSA-N 219222 US9303033, S15, Table 33A, Compound 38 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219222&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336005 329994401 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384688 CCOCCNc1nc(Nc2cccc(CN)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C20H23N9O3/c1-2-32-7-6-22-19-28-18(24-14-5-3-4-12(8-14)10-21)26-16-13(11-23-29(16)19)9-15-17(30)27-20(31)25-15/h3-5,8-9,11H,2,6-7,10,21H2,1H3,(H2,22,24,26,28)(H2,25,27,30,31)/b15-9- XOLODDLKNHAPIO-DHDCSXOGSA-N 219223 US9303033, T15, Table 33A, Compound 39 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219223&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336011 329994402 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384689 FC(F)(F)Oc1cccc(c1)-c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H14F3N7O3/c20-19(21,22)32-12-3-1-2-9(6-12)14-26-15-10(7-13-16(30)28-18(31)25-13)8-23-29(15)17(27-14)24-11-4-5-11/h1-3,6-8,11H,4-5H2,(H,24,26,27)(H2,25,28,30,31)/b13-7- LWIJTYNZCAZVPG-QPEQYQDCSA-N 219224 US9303033, U15, Table 33A, Compound 40 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219224 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219224&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67252894 329994403 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384690 Brc1ncc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)s1 InChI=1S/C16H14BrN9O2S/c17-13-18-5-9(29-13)6-19-14-23-11-7(3-10-12(27)24-16(28)22-10)4-20-26(11)15(25-14)21-8-1-2-8/h3-5,8H,1-2,6H2,(H2,19,21,23,25)(H2,22,24,27,28)/b10-3- CLMJFCGZMTUBMB-KMKOMSMNSA-N 219225 US9303033, V15, Table 33A, Compound 41 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219225 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219225&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335768 329994404 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384691 CN(c1ccccc1)c1nc(NC2CCCC2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C21H22N8O2/c1-28(15-9-3-2-4-10-15)21-27-19(23-14-7-5-6-8-14)25-17-13(12-22-29(17)21)11-16-18(30)26-20(31)24-16/h2-4,9-12,14H,5-8H2,1H3,(H,23,25)(H2,24,26,30,31)/b16-11- YFJNYRIACWQXEZ-WJDWOHSUSA-N 219226 US9303033, W15, Table 33A, Compound 42 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219226 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219226&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335937 329994405 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384692 FC(F)(F)c1cccc(Nc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C19H15F3N8O2/c20-19(21,22)10-2-1-3-12(7-10)24-16-27-14-9(6-13-15(31)28-18(32)26-13)8-23-30(14)17(29-16)25-11-4-5-11/h1-3,6-8,11H,4-5H2,(H2,24,25,27,29)(H2,26,28,31,32)/b13-6- AVTXBZGFYJZSCB-MLPAPPSSSA-N 219228 US9303033, Y15, Table 33A, Compound 44 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219228 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219228&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335936 329994407 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384693 FC(F)(F)Oc1cccc(Nc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C19H15F3N8O3/c20-19(21,22)33-12-3-1-2-11(7-12)24-16-27-14-9(6-13-15(31)28-18(32)26-13)8-23-30(14)17(29-16)25-10-4-5-10/h1-3,6-8,10H,4-5H2,(H2,24,25,27,29)(H2,26,28,31,32)/b13-6- WDZSYFANJIAYEV-MLPAPPSSSA-N 219229 US9303033, Z15, Table 33A, Compound 45 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219229 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219229&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335935 329994408 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384694 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(Nc3ccc(CN4CCOCC4)cc3)nc12 InChI=1S/C23H25N9O3/c33-20-18(27-23(34)29-20)11-15-12-24-32-19(15)28-21(30-22(32)26-17-5-6-17)25-16-3-1-14(2-4-16)13-31-7-9-35-10-8-31/h1-4,11-12,17H,5-10,13H2,(H2,25,26,28,30)(H2,27,29,33,34)/b18-11- QPDUXGAGPDAVLQ-WQRHYEAKSA-N 219230 US9303033, A16, Table 33A, Compound 46 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219230 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219230&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335950 329994409 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384695 CN1CCN(CC1)c1ccc(Nc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C23H26N10O2/c1-31-8-10-32(11-9-31)17-6-4-15(5-7-17)25-21-28-19-14(12-18-20(34)29-23(35)27-18)13-24-33(19)22(30-21)26-16-2-3-16/h4-7,12-13,16H,2-3,8-11H2,1H3,(H2,25,26,28,30)(H2,27,29,34,35)/b18-12- DKAIOEVGDBCZHQ-PDGQHHTCSA-N 219231 US9303033, B16, Table 33A, Compound 47 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219231 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219231&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335307 329994410 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384696 Fc1cc(F)cc(Nc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C18H14F2N8O2/c19-9-4-10(20)6-12(5-9)22-16-25-14-8(3-13-15(29)26-18(30)24-13)7-21-28(14)17(27-16)23-11-1-2-11/h3-7,11H,1-2H2,(H2,22,23,25,27)(H2,24,26,29,30)/b13-3- QTNKGDQBZPVCHF-DXNYSGJVSA-N 219232 US9303033, C16, Table 33A, Compound 48 Casein kinase II subunit beta 1769.5 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219232 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219232&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335947 329994411 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384697 Fc1ccc(Nc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1Cl InChI=1S/C18H14ClFN8O2/c19-11-6-10(3-4-12(11)20)22-16-25-14-8(5-13-15(29)26-18(30)24-13)7-21-28(14)17(27-16)23-9-1-2-9/h3-7,9H,1-2H2,(H2,22,23,25,27)(H2,24,26,29,30)/b13-5- VGKNYQUHFUAEIU-ACAGNQJTSA-N 219233 US9303033, D16, Table 33A, Compound 49 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219233 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219233&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335135 329994412 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384698 COc1ccc(Nc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1Cl InChI=1S/C19H17ClN8O3/c1-31-14-5-4-11(7-12(14)20)22-17-25-15-9(6-13-16(29)26-19(30)24-13)8-21-28(15)18(27-17)23-10-2-3-10/h4-8,10H,2-3H2,1H3,(H2,22,23,25,27)(H2,24,26,29,30)/b13-6- SWMAPMLFFOUFIF-MLPAPPSSSA-N 219234 US9303033, E16, Table 33A, Compound 50 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219234 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219234&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335582 329994413 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384699 Fc1ccc(Nc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c(F)c1 InChI=1S/C18H14F2N8O2/c19-9-1-4-12(11(20)6-9)23-16-25-14-8(5-13-15(29)26-18(30)24-13)7-21-28(14)17(27-16)22-10-2-3-10/h1,4-7,10H,2-3H2,(H2,22,23,25,27)(H2,24,26,29,30)/b13-5- CNESDQNNGLDKKN-ACAGNQJTSA-N 219235 US9303033, F16, Table 33A, Compound 51 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219235 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219235&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335943 329994414 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384700 Fc1ccc(Nc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1F InChI=1S/C18H14F2N8O2/c19-11-4-3-10(6-12(11)20)22-16-25-14-8(5-13-15(29)26-18(30)24-13)7-21-28(14)17(27-16)23-9-1-2-9/h3-7,9H,1-2H2,(H2,22,23,25,27)(H2,24,26,29,30)/b13-5- SXWRFSYNHYMYJG-ACAGNQJTSA-N 219236 US9303033, G16, Table 33A, Compound 52 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219236 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219236&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335581 329994415 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384701 FC(F)(F)c1cc(Nc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)ccc1Cl InChI=1S/C19H14ClF3N8O2/c20-12-4-3-10(6-11(12)19(21,22)23)25-16-28-14-8(5-13-15(32)29-18(33)27-13)7-24-31(14)17(30-16)26-9-1-2-9/h3-7,9H,1-2H2,(H2,25,26,28,30)(H2,27,29,32,33)/b13-5- PLLSAXNZCWMNKI-ACAGNQJTSA-N 219237 US9303033, H16, Table 33A, Compound 53 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219237 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219237&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335926 329994416 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384702 FC(F)(F)CNc1nc(Nc2cccc(OCCN3CCOCC3)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C23H24F3N9O4/c24-23(25,26)13-27-21-33-20(31-18-14(12-28-35(18)21)10-17-19(36)32-22(37)30-17)29-15-2-1-3-16(11-15)39-9-6-34-4-7-38-8-5-34/h1-3,10-12H,4-9,13H2,(H2,27,29,31,33)(H2,30,32,36,37)/b17-10- FWOSSSXDDIHFQA-YVLHZVERSA-N 219238 US9303033, I16, Table 33A, Compound 54 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219238 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219238&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335570 329994417 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384703 FC(F)(F)CNc1nc(Nc2cccc(CN3CCCC3)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C22H22F3N9O2/c23-22(24,25)12-26-20-32-19(28-15-5-3-4-13(8-15)11-33-6-1-2-7-33)30-17-14(10-27-34(17)20)9-16-18(35)31-21(36)29-16/h3-5,8-10H,1-2,6-7,11-12H2,(H2,26,28,30,32)(H2,29,31,35,36)/b16-9- KNWIJMNITNNSOJ-SXGWCWSVSA-N 219239 US9303033, J16, Table 33A, Compound 55 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219239 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219239&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335776 329994418 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384704 FC(F)(F)CNc1nc(Nc2cccc(c2)C#C)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C19H13F3N8O2/c1-2-10-4-3-5-12(6-10)25-16-27-14-11(7-13-15(31)28-18(32)26-13)8-24-30(14)17(29-16)23-9-19(20,21)22/h1,3-8H,9H2,(H2,23,25,27,29)(H2,26,28,31,32)/b13-7- RVSSPFILOJBAFE-QPEQYQDCSA-N 219240 US9303033, K16, Table 33A, Compound 56 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219240 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219240&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 88941272 329994419 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384705 FC(F)(F)CNc1nc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C17H12ClF3N8O2/c18-9-2-1-3-10(5-9)24-14-26-12-8(4-11-13(30)27-16(31)25-11)6-23-29(12)15(28-14)22-7-17(19,20)21/h1-6H,7H2,(H2,22,24,26,28)(H2,25,27,30,31)/b11-4- XGMYZXQZOSFVMK-WCIBSUBMSA-N 219241 US9303033, L16, Table 33A, Compound 57 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219241 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219241&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335154 329994420 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384706 CC(C)CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C16H20N8O2/c1-8(2)6-17-14-21-12-9(5-11-13(25)22-16(26)20-11)7-18-24(12)15(23-14)19-10-3-4-10/h5,7-8,10H,3-4,6H2,1-2H3,(H2,17,19,21,23)(H2,20,22,25,26)/b11-5- LTEYFGTVFNYTHH-WZUFQYTHSA-N 219248 US9303033, S16, Table 33A, Compound 64 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219248 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219248&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335136 329994427 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384707 CC(C)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C15H18N8O2/c1-7(2)17-13-20-11-8(5-10-12(24)21-15(25)19-10)6-16-23(11)14(22-13)18-9-3-4-9/h5-7,9H,3-4H2,1-2H3,(H2,17,18,20,22)(H2,19,21,24,25)/b10-5- MTPYQRSMFLVQCN-YHYXMXQVSA-N 219249 US9303033, T16, Table 33A, Compound 65 Casein kinase II subunit beta 1939.1 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219249 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219249&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335572 329994428 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384708 FC1CCN(CC1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C17H19FN8O2/c18-10-3-5-25(6-4-10)15-22-13-9(7-12-14(27)23-17(28)21-12)8-19-26(13)16(24-15)20-11-1-2-11/h7-8,10-11H,1-6H2,(H,20,22,24)(H2,21,23,27,28)/b12-7- ZRHLRYFJCSXGDG-GHXNOFRVSA-N 219250 US9303033, U16, Table 33A, Compound 66 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219250 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219250&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335781 329994429 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384709 FC(F)CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C14H14F2N8O2/c15-9(16)5-17-12-21-10-6(3-8-11(25)22-14(26)20-8)4-18-24(10)13(23-12)19-7-1-2-7/h3-4,7,9H,1-2,5H2,(H2,17,19,21,23)(H2,20,22,25,26)/b8-3- XLAZKMXUIRXNNQ-BAQGIRSFSA-N 219251 US9303033, V16, Table 33A, Compound 67 Casein kinase II subunit beta 2438 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219251 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219251&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 88941225 329994430 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384710 FC1CN(C1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C15H15FN8O2/c16-8-5-23(6-8)13-20-11-7(3-10-12(25)21-15(26)19-10)4-17-24(11)14(22-13)18-9-1-2-9/h3-4,8-9H,1-2,5-6H2,(H,18,20,22)(H2,19,21,25,26)/b10-3- CLZUSUKHKGWDIZ-KMKOMSMNSA-N 219252 US9303033, W16, Table 33A, Compound 68 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219252 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219252&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336015 329994431 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384711 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)N1CCC1 InChI=1S/C15H16N8O2/c24-12-10(18-15(25)20-12)6-8-7-16-23-11(8)19-13(22-4-1-5-22)21-14(23)17-9-2-3-9/h6-7,9H,1-5H2,(H,17,19,21)(H2,18,20,24,25)/b10-6- ZHAQDLPJKNXUCS-POHAHGRESA-N 219253 US9303033, X16, Table 33A, Compound 69 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219253 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219253&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335161 329994432 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384712 FC1(F)CCN(CC1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C17H18F2N8O2/c18-17(19)3-5-26(6-4-17)14-23-12-9(7-11-13(28)24-16(29)22-11)8-20-27(12)15(25-14)21-10-1-2-10/h7-8,10H,1-6H2,(H,21,23,25)(H2,22,24,28,29)/b11-7- RUKCEYJGRGPFQH-XFFZJAGNSA-N 219254 US9303033, Y16, Table 33A, Compound 70 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219254&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335769 329994433 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384713 O[C@H]1CCN(C1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C16H18N8O3/c25-10-3-4-23(7-10)14-20-12-8(5-11-13(26)21-16(27)19-11)6-17-24(12)15(22-14)18-9-1-2-9/h5-6,9-10,25H,1-4,7H2,(H,18,20,22)(H2,19,21,26,27)/b11-5-/t10-/m0/s1 XKKJLJRASFYZGX-QIMWGGGBSA-N 219255 US9303033, Z16, Table 33A, Compound 71 Casein kinase II subunit beta <1000 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219255 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219255&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335996 329994434 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384714 O[C@@H]1CCN(C1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C16H18N8O3/c25-10-3-4-23(7-10)14-20-12-8(5-11-13(26)21-16(27)19-11)6-17-24(12)15(22-14)18-9-1-2-9/h5-6,9-10,25H,1-4,7H2,(H,18,20,22)(H2,19,21,26,27)/b11-5-/t10-/m1/s1 XKKJLJRASFYZGX-KMFOOYFMSA-N 219256 US9303033, A17, Table 33A, Compound 72 Casein kinase II subunit beta 1862.9 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219256&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335140 329994435 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384715 OC[C@@H]1CCCN1c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C17H20N8O3/c26-8-11-2-1-5-24(11)15-21-13-9(6-12-14(27)22-17(28)20-12)7-18-25(13)16(23-15)19-10-3-4-10/h6-7,10-11,26H,1-5,8H2,(H,19,21,23)(H2,20,22,27,28)/b12-6-/t11-/m0/s1 HXRKAWMYSNFTRK-RMCZBGCRSA-N 219257 US9303033, B17, Table 33A, Compound 73 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219257&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335162 329994436 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384716 OC[C@H]1CCCN1c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C17H20N8O3/c26-8-11-2-1-5-24(11)15-21-13-9(6-12-14(27)22-17(28)20-12)7-18-25(13)16(23-15)19-10-3-4-10/h6-7,10-11,26H,1-5,8H2,(H,19,21,23)(H2,20,22,27,28)/b12-6-/t11-/m1/s1 HXRKAWMYSNFTRK-MDUDVEDUSA-N 219258 US9303033, C17, Table 33A, Compound 74 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219258 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219258&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335147 329994437 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384717 NC1CCN(C1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C16H19N9O2/c17-9-3-4-24(7-9)14-21-12-8(5-11-13(26)22-16(27)20-11)6-18-25(12)15(23-14)19-10-1-2-10/h5-6,9-10H,1-4,7,17H2,(H,19,21,23)(H2,20,22,26,27)/b11-5- IQYXVCBCBSNJKE-WZUFQYTHSA-N 219259 US9303033, D17, Table 33A, Compound 75 Casein kinase II subunit beta 1884 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219259 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219259&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335953 329994438 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384718 CN1CCC(CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H23N9O2/c1-26-6-4-12(5-7-26)20-16-23-14-10(8-13-15(28)24-18(29)22-13)9-19-27(14)17(25-16)21-11-2-3-11/h8-9,11-12H,2-7H2,1H3,(H2,20,21,23,25)(H2,22,24,28,29)/b13-8- NYIYFGGYGJSDBG-JYRVWZFOSA-N 219260 US9303033, E17, Table 33A, Compound 76 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219260 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219260&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335782 329994439 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384719 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NC3CCNC3)nc12 InChI=1S/C16H19N9O2/c26-13-11(21-16(27)23-13)5-8-6-18-25-12(8)22-14(19-10-3-4-17-7-10)24-15(25)20-9-1-2-9/h5-6,9-10,17H,1-4,7H2,(H2,19,20,22,24)(H2,21,23,26,27)/b11-5- WIJKVMMJDVEDQP-WZUFQYTHSA-N 219261 US9303033, F17, Table 33A, Compound 77 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219261 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219261&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335199 329994440 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384720 CC(O)CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C15H18N8O3/c1-7(24)5-16-13-20-11-8(4-10-12(25)21-15(26)19-10)6-17-23(11)14(22-13)18-9-2-3-9/h4,6-7,9,24H,2-3,5H2,1H3,(H2,16,18,20,22)(H2,19,21,25,26)/b10-4- HDCYAPZYFAVEEU-WMZJFQQLSA-N 219262 US9303033, G17, Table 33A, Compound 78 Casein kinase II subunit beta <1000 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219262 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219262&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336023 329994441 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384721 N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H23N9O2/c19-10-1-3-11(4-2-10)21-16-24-14-9(7-13-15(28)25-18(29)23-13)8-20-27(14)17(26-16)22-12-5-6-12/h7-8,10-12H,1-6,19H2,(H2,21,22,24,26)(H2,23,25,28,29)/b13-7-/t10-,11- NHXZVVIDPXHKJF-GHCBGBTPSA-N 219263 US9303033, H17, Table 33A, Compound 79 Casein kinase II subunit beta <1000 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219263 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219263&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67253313 329994442 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384722 Clc1cccc(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C18H14ClN7O3/c19-10-2-1-3-12(7-10)29-18-23-14-9(6-13-15(27)24-17(28)22-13)8-20-26(14)16(25-18)21-11-4-5-11/h1-3,6-8,11H,4-5H2,(H,21,23,25)(H2,22,24,27,28)/b13-6- RPCMXNFXSNSLCR-MLPAPPSSSA-N 219264 US9303033, E34, Table 39A, Compound 1::US9303033, I17, Table 33A, Compound 80 Casein kinase II subunit beta 1190.3 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219264 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219264&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67254434 329994443 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384723 Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C12H12N8O2/c13-10-17-8-5(3-7-9(21)18-12(22)16-7)4-14-20(8)11(19-10)15-6-1-2-6/h3-4,6H,1-2H2,(H3,13,15,17,19)(H2,16,18,21,22)/b7-3- UDFNOCZIRYYIIZ-CLTKARDFSA-N 219265 US9303033, J17, Table 33A, Compound 81 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219265 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219265&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335315 329994444 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384724 CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C13H14N8O2/c1-14-11-18-9-6(4-8-10(22)19-13(23)17-8)5-15-21(9)12(20-11)16-7-2-3-7/h4-5,7H,2-3H2,1H3,(H2,14,16,18,20)(H2,17,19,22,23)/b8-4- CPVHQGPEJXLLSF-YWEYNIOJSA-N 219266 US9303033, K17, Table 33A, Compound 82 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219266 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219266&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335591 329994445 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384725 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NC3CCNCC3)nc12 InChI=1S/C17H21N9O2/c27-14-12(22-17(28)24-14)7-9-8-19-26-13(9)23-15(20-11-3-5-18-6-4-11)25-16(26)21-10-1-2-10/h7-8,10-11,18H,1-6H2,(H2,20,21,23,25)(H2,22,24,27,28)/b12-7- LZKMQJPBAAWNKE-GHXNOFRVSA-N 219267 US9303033, L17, Table 33A, Compound 83 Casein kinase II subunit beta 2078.1 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219267 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219267&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336014 329994446 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384726 CN1CCC(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)CC1 InChI=1S/C19H25N9O2/c1-27-6-4-11(5-7-27)9-20-17-24-15-12(8-14-16(29)25-19(30)23-14)10-21-28(15)18(26-17)22-13-2-3-13/h8,10-11,13H,2-7,9H2,1H3,(H2,20,22,24,26)(H2,23,25,29,30)/b14-8- JWRJEJJFDIYQHN-ZSOIEALJSA-N 219268 US9303033, M17, Table 33A, Compound 84 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219268 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219268&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335780 329994447 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384727 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NN3CCCC3)nc12 InChI=1S/C16H19N9O2/c26-13-11(19-16(27)21-13)7-9-8-17-25-12(9)20-14(23-24-5-1-2-6-24)22-15(25)18-10-3-4-10/h7-8,10H,1-6H2,(H2,18,20,22,23)(H2,19,21,26,27)/b11-7- QVGYEJUJGPBCDZ-XFFZJAGNSA-N 219269 US9303033, N17, Table 33A, Compound 85 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219269 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219269&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335783 329994448 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384728 CCN1CCCC1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H25N9O2/c1-2-27-7-3-4-13(27)10-20-17-24-15-11(8-14-16(29)25-19(30)23-14)9-21-28(15)18(26-17)22-12-5-6-12/h8-9,12-13H,2-7,10H2,1H3,(H2,20,22,24,26)(H2,23,25,29,30)/b14-8- GJUMYDWCFSNNMY-ZSOIEALJSA-N 219270 US9303033, O17, Table 33A, Compound 86 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219270 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219270&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335576 329994449 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384729 CN(C)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C14H16N8O2/c1-21(2)12-18-10-7(5-9-11(23)19-14(24)17-9)6-15-22(10)13(20-12)16-8-3-4-8/h5-6,8H,3-4H2,1-2H3,(H,16,18,20)(H2,17,19,23,24)/b9-5- OBQXFGGTFHGFPO-UITAMQMPSA-N 219271 US9303033, P17, Table 33A, Compound 87 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219271 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219271&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335594 329994450 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384730 N[C@@H]1CCCC[C@H]1Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H23N9O2/c19-11-3-1-2-4-12(11)22-16-24-14-9(7-13-15(28)25-18(29)23-13)8-20-27(14)17(26-16)21-10-5-6-10/h7-8,10-12H,1-6,19H2,(H2,21,22,24,26)(H2,23,25,28,29)/b13-7-/t11-,12-/m1/s1 VRVXDUAIFMNCRZ-YZDJHDEESA-N 219272 US9303033, Q17, Table 33A, Compound 88 Casein kinase II subunit beta 1628.1 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219272 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219272&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335310 329994451 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384731 OCC1(CCCC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H22N8O3/c27-9-18(5-1-2-6-18)25-15-22-13-10(7-12-14(28)23-17(29)21-12)8-19-26(13)16(24-15)20-11-3-4-11/h7-8,11,27H,1-6,9H2,(H2,20,22,24,25)(H2,21,23,28,29)/b12-7- GSBSLIBTUIYMHV-GHXNOFRVSA-N 219273 US9303033, R17, Table 33A, Compound 89 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219273 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219273&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335127 329994452 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384732 O[C@H]1CCC[C@@H]1Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C17H20N8O3/c26-12-3-1-2-10(12)20-15-22-13-8(6-11-14(27)23-17(28)21-11)7-18-25(13)16(24-15)19-9-4-5-9/h6-7,9-10,12,26H,1-5H2,(H2,19,20,22,24)(H2,21,23,27,28)/b11-6-/t10-,12-/m0/s1 VSIQQKLFPIZCNP-COPNJLSZSA-N 219274 US9303033, S17, Table 33A, Compound 90 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219274 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219274&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336024 329994453 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384733 NC1CCCCC1Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H23N9O2/c19-11-3-1-2-4-12(11)22-16-24-14-9(7-13-15(28)25-18(29)23-13)8-20-27(14)17(26-16)21-10-5-6-10/h7-8,10-12H,1-6,19H2,(H2,21,22,24,26)(H2,23,25,28,29)/b13-7- VRVXDUAIFMNCRZ-QPEQYQDCSA-N 219275 US9303033, T17, Table 33A, Compound 91 Casein kinase II subunit beta <1000 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219275 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219275&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335121 329994454 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384734 CCNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C14H16N8O2/c1-2-15-12-19-10-7(5-9-11(23)20-14(24)18-9)6-16-22(10)13(21-12)17-8-3-4-8/h5-6,8H,2-4H2,1H3,(H2,15,17,19,21)(H2,18,20,23,24)/b9-5- PWAAHEXRVFKGFV-UITAMQMPSA-N 219276 US9303033, U17, Table 33A, Compound 92 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219276 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219276&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336012 329994455 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384735 CN(C1CCN(C)C1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H23N9O2/c1-25-6-5-12(9-25)26(2)16-22-14-10(7-13-15(28)23-18(29)21-13)8-19-27(14)17(24-16)20-11-3-4-11/h7-8,11-12H,3-6,9H2,1-2H3,(H,20,22,24)(H2,21,23,28,29)/b13-7- FNTDXODUUJZZPM-QPEQYQDCSA-N 219277 US9303033, V17, Table 33A, Compound 93 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219277 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219277&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335784 329994456 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384736 CC(CO)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C15H18N8O3/c1-7(6-24)17-13-20-11-8(4-10-12(25)21-15(26)19-10)5-16-23(11)14(22-13)18-9-2-3-9/h4-5,7,9,24H,2-3,6H2,1H3,(H2,17,18,20,22)(H2,19,21,25,26)/b10-4- DZYWNQWLBRTRRD-WMZJFQQLSA-N 219278 US9303033, W17, Table 33A, Compound 94 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219278 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219278&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335309 329994457 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384737 CC1CCN(C1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C17H20N8O2/c1-9-4-5-24(8-9)15-21-13-10(6-12-14(26)22-17(27)20-12)7-18-25(13)16(23-15)19-11-2-3-11/h6-7,9,11H,2-5,8H2,1H3,(H,19,21,23)(H2,20,22,26,27)/b12-6- NYFKFGRERAFKPU-SDQBBNPISA-N 219279 US9303033, X17, Table 33A, Compound 95 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219279 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219279&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335314 329994458 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384738 CCC(CO)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C16H20N8O3/c1-2-9(7-25)18-14-21-12-8(5-11-13(26)22-16(27)20-11)6-17-24(12)15(23-14)19-10-3-4-10/h5-6,9-10,25H,2-4,7H2,1H3,(H2,18,19,21,23)(H2,20,22,26,27)/b11-5- ONQWERJIVQKYCU-WZUFQYTHSA-N 219280 US9303033, Y17, Table 33A, Compound 96 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219280 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219280&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336044 329994459 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384739 CC(C)(CO)CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C17H22N8O3/c1-17(2,8-26)7-18-14-22-12-9(5-11-13(27)23-16(28)21-11)6-19-25(12)15(24-14)20-10-3-4-10/h5-6,10,26H,3-4,7-8H2,1-2H3,(H2,18,20,22,24)(H2,21,23,27,28)/b11-5- RPVLQBKRAOUJPG-WZUFQYTHSA-N 219281 US9303033, Z17, Table 33A, Compound 97 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219281 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219281&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314568 329994460 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384740 C[C@@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C1CC1 InChI=1S/C17H20N8O2/c1-8(9-2-3-9)19-15-22-13-10(6-12-14(26)23-17(27)21-12)7-18-25(13)16(24-15)20-11-4-5-11/h6-9,11H,2-5H2,1H3,(H2,19,20,22,24)(H2,21,23,26,27)/b12-6-/t8-/m1/s1 LKVZMQNUGHTDFU-VNUQYUTRSA-N 219282 US9303033, A18, Table 33A, Compound 98 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219282 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219282&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335583 329994461 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384741 C[C@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C1CC1 InChI=1S/C17H20N8O2/c1-8(9-2-3-9)19-15-22-13-10(6-12-14(26)23-17(27)21-12)7-18-25(13)16(24-15)20-11-4-5-11/h6-9,11H,2-5H2,1H3,(H2,19,20,22,24)(H2,21,23,26,27)/b12-6-/t8-/m0/s1 LKVZMQNUGHTDFU-QJZKUFFDSA-N 219283 US9303033, B18, Table 33A, Compound 99 Casein kinase II subunit beta 1304 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219283 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219283&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335318 329994462 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384742 OCC1(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)CCCC1 InChI=1S/C19H24N8O3/c28-10-19(5-1-2-6-19)9-20-16-24-14-11(7-13-15(29)25-18(30)23-13)8-21-27(14)17(26-16)22-12-3-4-12/h7-8,12,28H,1-6,9-10H2,(H2,20,22,24,26)(H2,23,25,29,30)/b13-7- LGBAYENYZPLFGW-QPEQYQDCSA-N 219284 US9303033, C18, Table 33A, Compound 100 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219284 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219284&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335958 329994463 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384743 CC[C@H](CO)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C16H20N8O3/c1-2-9(7-25)18-14-21-12-8(5-11-13(26)22-16(27)20-11)6-17-24(12)15(23-14)19-10-3-4-10/h5-6,9-10,25H,2-4,7H2,1H3,(H2,18,19,21,23)(H2,20,22,26,27)/b11-5-/t9-/m1/s1 ONQWERJIVQKYCU-QQCYMQAYSA-N 219285 US9303033, D18, Table 33A, Compound 101 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219285 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219285&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335165 329994464 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384744 OC(=O)[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H22N8O4/c28-15-13(23-19(31)25-15)7-10-8-20-27-14(10)24-17(26-18(27)22-12-5-6-12)21-11-3-1-9(2-4-11)16(29)30/h7-9,11-12H,1-6H2,(H,29,30)(H2,21,22,24,26)(H2,23,25,28,31)/b13-7-/t9-,11- BXJFNSIEFGKTRY-GXIKPWHLSA-N 219286 US9303033, E18, Table 33A, Compound 102 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219286 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219286&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67254885 329994465 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384745 CC[C@@H](CO)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C16H20N8O3/c1-2-9(7-25)18-14-21-12-8(5-11-13(26)22-16(27)20-11)6-17-24(12)15(23-14)19-10-3-4-10/h5-6,9-10,25H,2-4,7H2,1H3,(H2,18,19,21,23)(H2,20,22,26,27)/b11-5-/t9-/m0/s1 ONQWERJIVQKYCU-BVBCSLMJSA-N 219287 US9303033, F18, Table 33A, Compound 103 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219287 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219287&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336051 329994466 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384746 O[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H22N8O3/c27-12-5-3-10(4-6-12)20-16-23-14-9(7-13-15(28)24-18(29)22-13)8-19-26(14)17(25-16)21-11-1-2-11/h7-8,10-12,27H,1-6H2,(H2,20,21,23,25)(H2,22,24,28,29)/b13-7-/t10-,12- PVOZZXGPKPELJM-PSWRREKQSA-N 219288 US9303033, G18, Table 33A, Compound 104 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219288 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219288&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335321 329994467 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384747 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NC3CCS(=O)(=O)C3)nc12 InChI=1S/C16H18N8O4S/c25-13-11(20-16(26)22-13)5-8-6-17-24-12(8)21-14(23-15(24)19-9-1-2-9)18-10-3-4-29(27,28)7-10/h5-6,9-10H,1-4,7H2,(H2,18,19,21,23)(H2,20,22,25,26)/b11-5- QCJFGJMXUVXLBX-WZUFQYTHSA-N 219289 US9303033, H18, Table 33A, Compound 105 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219289&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335785 329994468 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384748 CN1CCCN(CC1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H23N9O2/c1-25-5-2-6-26(8-7-25)16-22-14-11(9-13-15(28)23-18(29)21-13)10-19-27(14)17(24-16)20-12-3-4-12/h9-10,12H,2-8H2,1H3,(H,20,22,24)(H2,21,23,28,29)/b13-9- DRBPUALSCDYXOJ-LCYFTJDESA-N 219290 US9303033, I18, Table 33A, Compound 106 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219290&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335164 329994469 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384749 CN(C)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C14H17N9O2/c1-22(2)21-12-18-10-7(5-9-11(24)19-14(25)17-9)6-15-23(10)13(20-12)16-8-3-4-8/h5-6,8H,3-4H2,1-2H3,(H2,16,18,20,21)(H2,17,19,24,25)/b9-5- YGDDXOYULAIASV-UITAMQMPSA-N 219291 US9303033, J18, Table 33A, Compound 107 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219291 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219291&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335959 329994470 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384750 FC(F)(F)CNNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C14H14F3N9O2/c15-14(16,17)5-18-25-11-22-9-6(3-8-10(27)23-13(28)21-8)4-19-26(9)12(24-11)20-7-1-2-7/h3-4,7,18H,1-2,5H2,(H2,20,22,24,25)(H2,21,23,27,28)/b8-3- ZNDLHTILMVMXDO-BAQGIRSFSA-N 219292 US9303033, K18, Table 33A, Compound 108 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219292 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219292&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335789 329994471 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384751 COC[C@H]1CCCN1Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H23N9O3/c1-30-9-12-3-2-6-26(12)25-16-22-14-10(7-13-15(28)23-18(29)21-13)8-19-27(14)17(24-16)20-11-4-5-11/h7-8,11-12H,2-6,9H2,1H3,(H2,20,22,24,25)(H2,21,23,28,29)/b13-7-/t12-/m1/s1 IQNQKELIKQJRHS-BFTHVDOESA-N 219293 US9303033, L18, Table 33A, Compound 109 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219293&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335963 329994472 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384752 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NN3CCCCC3)nc12 InChI=1S/C17H21N9O2/c27-14-12(20-17(28)22-14)8-10-9-18-26-13(10)21-15(23-16(26)19-11-4-5-11)24-25-6-2-1-3-7-25/h8-9,11H,1-7H2,(H2,19,21,23,24)(H2,20,22,27,28)/b12-8- RFHPUZLQSOKRTC-WQLSENKSSA-N 219294 US9303033, M18, Table 33A, Compound 110 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219294 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219294&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336068 329994473 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384753 O[C@H]1Cc2ccccc2[C@H]1Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H20N8O3/c30-15-8-10-3-1-2-4-13(10)16(15)25-19-26-17-11(7-14-18(31)27-21(32)24-14)9-22-29(17)20(28-19)23-12-5-6-12/h1-4,7,9,12,15-16,30H,5-6,8H2,(H2,23,25,26,28)(H2,24,27,31,32)/b14-7-/t15-,16+/m0/s1 IFVKGXXFFHIRNY-USCQQBMNSA-N 219295 US9303033, N18, Table 33A, Compound 111 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219295 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219295&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336054 329994474 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384754 O[C@@H]1Cc2ccccc2[C@@H]1Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H20N8O3/c30-15-8-10-3-1-2-4-13(10)16(15)25-19-26-17-11(7-14-18(31)27-21(32)24-14)9-22-29(17)20(28-19)23-12-5-6-12/h1-4,7,9,12,15-16,30H,5-6,8H2,(H2,23,25,26,28)(H2,24,27,31,32)/b14-7-/t15-,16+/m1/s1 IFVKGXXFFHIRNY-QAIKFOBFSA-N 219296 US9303033, O18, Table 33A, Compound 112 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219296&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336070 329994475 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384755 CC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1 InChI=1S/C20H20N8O2/c1-11(12-5-3-2-4-6-12)22-18-25-16-13(9-15-17(29)26-20(30)24-15)10-21-28(16)19(27-18)23-14-7-8-14/h2-6,9-11,14H,7-8H2,1H3,(H2,22,23,25,27)(H2,24,26,29,30)/b15-9- QLPJGJKEKMNXSN-DHDCSXOGSA-N 219297 US9303033, P18, Table 33A, Compound 113 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219297 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219297&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335592 329994476 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384756 OC(CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccc(F)cc1 InChI=1S/C20H19FN8O3/c21-12-3-1-10(2-4-12)15(30)9-22-18-26-16-11(7-14-17(31)27-20(32)25-14)8-23-29(16)19(28-18)24-13-5-6-13/h1-4,7-8,13,15,30H,5-6,9H2,(H2,22,24,26,28)(H2,25,27,31,32)/b14-7- VCWHMYKGSZBNBE-AUWJEWJLSA-N 219298 US9303033, Q18, Table 33A, Compound 114 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219298 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219298&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335329 329994477 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384757 OC(CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccn1 InChI=1S/C19H19N9O3/c29-14(12-3-1-2-6-20-12)9-21-17-25-15-10(7-13-16(30)26-19(31)24-13)8-22-28(15)18(27-17)23-11-4-5-11/h1-3,6-8,11,14,29H,4-5,9H2,(H2,21,23,25,27)(H2,24,26,30,31)/b13-7- JSPKYDAABDFAKP-QPEQYQDCSA-N 219299 US9303033, R18, Table 33A, Compound 115 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219299&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335962 329994478 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384758 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3ccccc3)nc12 InChI=1S/C19H18N8O2/c28-16-14(23-19(29)25-16)8-12-10-21-27-15(12)24-17(26-18(27)22-13-6-7-13)20-9-11-4-2-1-3-5-11/h1-5,8,10,13H,6-7,9H2,(H2,20,22,24,26)(H2,23,25,28,29)/b14-8- JQKQATZIOPPLBC-ZSOIEALJSA-N 219300 US9303033, S18, Table 33A, Compound 116 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219300 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219300&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335587 329994479 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384759 FC(F)(F)c1cccc(NNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C19H16F3N9O2/c20-19(21,22)10-2-1-3-12(7-10)29-30-16-26-14-9(6-13-15(32)27-18(33)25-13)8-23-31(14)17(28-16)24-11-4-5-11/h1-3,6-8,11,29H,4-5H2,(H2,24,26,28,30)(H2,25,27,32,33)/b13-6- ZPCBGHZYZTUNHR-MLPAPPSSSA-N 219301 US9303033, T18, Table 33A, Compound 117 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219301 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219301&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335968 329994480 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384760 COC[C@@H]1CCCN1Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H23N9O3/c1-30-9-12-3-2-6-26(12)25-16-22-14-10(7-13-15(28)23-18(29)21-13)8-19-27(14)17(24-16)20-11-4-5-11/h7-8,11-12H,2-6,9H2,1H3,(H2,20,22,24,25)(H2,21,23,28,29)/b13-7-/t12-/m0/s1 IQNQKELIKQJRHS-BPLGCGBFSA-N 219302 US9303033, U18, Table 33A, Compound 118 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219302 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219302&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335137 329994481 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384761 N[C@H]1CC[C@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H23N9O2/c19-10-1-3-11(4-2-10)21-16-24-14-9(7-13-15(28)25-18(29)23-13)8-20-27(14)17(26-16)22-12-5-6-12/h7-8,10-12H,1-6,19H2,(H2,21,22,24,26)(H2,23,25,28,29)/b13-7-/t10-,11+ NHXZVVIDPXHKJF-OWDBWLNLSA-N 219303 US9303033, V18, Table 33A, Compound 119 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219303 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219303&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67253313 329994482 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384762 NC(=O)[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H23N9O3/c20-14(29)9-1-3-11(4-2-9)22-17-25-15-10(7-13-16(30)26-19(31)24-13)8-21-28(15)18(27-17)23-12-5-6-12/h7-9,11-12H,1-6H2,(H2,20,29)(H2,22,23,25,27)(H2,24,26,30,31)/b13-7-/t9-,11- ZVXKASADPSGYGF-GXIKPWHLSA-N 219304 US9303033, W18, Table 33A, Compound 120 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219304 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219304&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67253123 329994483 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384763 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCCc3ccccn3)nc12 InChI=1S/C19H19N9O2/c29-16-14(24-19(30)26-16)9-11-10-22-28-15(11)25-17(27-18(28)23-13-4-5-13)21-8-6-12-3-1-2-7-20-12/h1-3,7,9-10,13H,4-6,8H2,(H2,21,23,25,27)(H2,24,26,29,30)/b14-9- JYZOWQBBPNLCQG-ZROIWOOFSA-N 219305 US9303033, X18, Table 33A, Compound 121 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219305 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219305&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336073 329994484 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384764 CNC(=O)[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H25N9O3/c1-21-16(30)10-2-4-12(5-3-10)23-18-26-15-11(8-14-17(31)27-20(32)25-14)9-22-29(15)19(28-18)24-13-6-7-13/h8-10,12-13H,2-7H2,1H3,(H,21,30)(H2,23,24,26,28)(H2,25,27,31,32)/b14-8-/t10-,12- MSNRSVUNGBPFCO-CLQUIVHVSA-N 219306 US9303033, Y18, Table 33A, Compound 122 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219306 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219306&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67253975 329994485 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384765 Cc1nonc1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C16H16N10O3/c1-7-11(25-29-24-7)6-17-14-21-12-8(4-10-13(27)22-16(28)20-10)5-18-26(12)15(23-14)19-9-2-3-9/h4-5,9H,2-3,6H2,1H3,(H2,17,19,21,23)(H2,20,22,27,28)/b10-4- QEYGPZQLNLVJCT-WMZJFQQLSA-N 219307 US9303033, Z18, Table 33A, Compound 123 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219307 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219307&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335786 329994486 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384766 CN(C)c1ccccc1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H23N9O2/c1-29(2)16-6-4-3-5-12(16)10-22-19-26-17-13(9-15-18(31)27-21(32)25-15)11-23-30(17)20(28-19)24-14-7-8-14/h3-6,9,11,14H,7-8,10H2,1-2H3,(H2,22,24,26,28)(H2,25,27,31,32)/b15-9- NZZJCKSQVSIHFI-DHDCSXOGSA-N 219308 US9303033, A19, Table 33A, Compound 124 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219308 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219308&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335584 329994487 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384767 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)N1CCN(CC1)c1ccccn1 InChI=1S/C21H22N10O2/c32-18-15(25-21(33)27-18)11-13-12-23-31-17(13)26-19(28-20(31)24-14-4-5-14)30-9-7-29(8-10-30)16-3-1-2-6-22-16/h1-3,6,11-12,14H,4-5,7-10H2,(H,24,26,28)(H2,25,27,32,33)/b15-11- QWFLYCLHOJGNTP-PTNGSMBKSA-N 219309 US9303033, B19, Table 33A, Compound 125 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219309 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219309&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335586 329994488 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384768 CN(C)c1cccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C21H23N9O2/c1-29(2)15-5-3-4-12(8-15)10-22-19-26-17-13(9-16-18(31)27-21(32)25-16)11-23-30(17)20(28-19)24-14-6-7-14/h3-5,8-9,11,14H,6-7,10H2,1-2H3,(H2,22,24,26,28)(H2,25,27,31,32)/b16-9- CLYQECODTMXYLU-SXGWCWSVSA-N 219310 US9303033, C19, Table 33A, Compound 126 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219310 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219310&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336069 329994489 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384769 OC[C@@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1 InChI=1S/C20H20N8O3/c29-10-15(11-4-2-1-3-5-11)23-18-25-16-12(8-14-17(30)26-20(31)24-14)9-21-28(16)19(27-18)22-13-6-7-13/h1-5,8-9,13,15,29H,6-7,10H2,(H2,22,23,25,27)(H2,24,26,30,31)/b14-8-/t15-/m1/s1 MAQURAHVKKRNQG-CKNOQMABSA-N 219311 US9303033, D19, Table 33A, Compound 127 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219311 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219311&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336074 329994490 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384770 C[C@@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1 InChI=1S/C20H20N8O2/c1-11(12-5-3-2-4-6-12)22-18-25-16-13(9-15-17(29)26-20(30)24-15)10-21-28(16)19(27-18)23-14-7-8-14/h2-6,9-11,14H,7-8H2,1H3,(H2,22,23,25,27)(H2,24,26,29,30)/b15-9-/t11-/m1/s1 QLPJGJKEKMNXSN-PDICVPPASA-N 219312 US9303033, E19, Table 33A, Compound 128 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219312 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219312&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335333 329994491 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384771 C[C@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1 InChI=1S/C20H20N8O2/c1-11(12-5-3-2-4-6-12)22-18-25-16-13(9-15-17(29)26-20(30)24-15)10-21-28(16)19(27-18)23-14-7-8-14/h2-6,9-11,14H,7-8H2,1H3,(H2,22,23,25,27)(H2,24,26,29,30)/b15-9-/t11-/m0/s1 QLPJGJKEKMNXSN-GPILYODUSA-N 219313 US9303033, F19, Table 33A, Compound 129 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219313 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219313&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336077 329994492 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384772 COc1ccc(cc1)[C@H](C)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H22N8O3/c1-11(12-3-7-15(32-2)8-4-12)23-19-26-17-13(9-16-18(30)27-21(31)25-16)10-22-29(17)20(28-19)24-14-5-6-14/h3-4,7-11,14H,5-6H2,1-2H3,(H2,23,24,26,28)(H2,25,27,30,31)/b16-9-/t11-/m0/s1 JLPLVKRLRGSRQO-RCEBRVLHSA-N 219314 US9303033, G19, Table 33A, Compound 130 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219314&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335596 329994493 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384773 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3cccc4ccccc34)nc12 InChI=1S/C23H20N8O2/c32-20-18(27-23(33)29-20)10-15-12-25-31-19(15)28-21(30-22(31)26-16-8-9-16)24-11-14-6-3-5-13-4-1-2-7-17(13)14/h1-7,10,12,16H,8-9,11H2,(H2,24,26,28,30)(H2,27,29,32,33)/b18-10- DMUMUGAVVTZORI-ZDLGFXPLSA-N 219315 US9303033, H19, Table 33A, Compound 131 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219315 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219315&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335966 329994494 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384774 COc1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c(OC)c1 InChI=1S/C21H22N8O4/c1-32-14-6-3-11(16(8-14)33-2)9-22-19-26-17-12(7-15-18(30)27-21(31)25-15)10-23-29(17)20(28-19)24-13-4-5-13/h3,6-8,10,13H,4-5,9H2,1-2H3,(H2,22,24,26,28)(H2,25,27,30,31)/b15-7- LYUKDNJSFUXQLZ-CHHVJCJISA-N 219316 US9303033, I19, Table 33A, Compound 132 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219316 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219316&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335585 329994495 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384775 NC(=O)c1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C20H19N9O3/c21-15(30)11-3-1-10(2-4-11)8-22-18-26-16-12(7-14-17(31)27-20(32)25-14)9-23-29(16)19(28-18)24-13-5-6-13/h1-4,7,9,13H,5-6,8H2,(H2,21,30)(H2,22,24,26,28)(H2,25,27,31,32)/b14-7- OILYOYQMHXNKDS-AUWJEWJLSA-N 219317 US9303033, J19, Table 33A, Compound 133 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219317 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219317&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335970 329994496 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384776 Clc1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C19H17ClN8O2/c20-12-3-1-10(2-4-12)8-21-17-25-15-11(7-14-16(29)26-19(30)24-14)9-22-28(15)18(27-17)23-13-5-6-13/h1-4,7,9,13H,5-6,8H2,(H2,21,23,25,27)(H2,24,26,29,30)/b14-7- CSHBPAVJCQTZAR-AUWJEWJLSA-N 219318 US9303033, K19, Table 33A, Compound 134 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219318 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219318&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335590 329994497 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384777 COCCCNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C16H20N8O3/c1-27-6-2-5-17-14-21-12-9(7-11-13(25)22-16(26)20-11)8-18-24(12)15(23-14)19-10-3-4-10/h7-8,10H,2-6H2,1H3,(H2,17,19,21,23)(H2,20,22,25,26)/b11-7- UZSNAGZAVVSXCI-XFFZJAGNSA-N 219319 US9303033, L19, Table 33A, Compound 135 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219319 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219319&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335588 329994498 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383815 Clc1cccc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C19H16ClN7O2/c20-11-2-1-3-13(7-11)22-15-8-16(23-12-4-5-12)27-17(25-15)10(9-21-27)6-14-18(28)26-19(29)24-14/h1-3,6-9,12,23H,4-5H2,(H,22,25)(H2,24,26,28,29)/b14-6- JFIDFEQEKNROTB-NSIKDUERSA-N 218845 US9303033, C1, Table 2A, Compound 1 Casein kinase II subunit beta 1300 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218845 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218845&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 53240563 329994068 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383816 CC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccc(F)cc1 InChI=1S/C20H19FN8O2/c1-10(11-2-4-13(21)5-3-11)23-18-26-16-12(8-15-17(30)27-20(31)25-15)9-22-29(16)19(28-18)24-14-6-7-14/h2-5,8-10,14H,6-7H2,1H3,(H2,23,24,26,28)(H2,25,27,30,31)/b15-8- ZKZDKVXNWCZCEZ-NVNXTCNLSA-N 219327 US9303033, A20, Table 37A, Compound 1 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219327 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219327&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335319 329994506 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383817 CC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1cccc(F)c1 InChI=1S/C20H19FN8O2/c1-10(11-3-2-4-13(21)7-11)23-18-26-16-12(8-15-17(30)27-20(31)25-15)9-22-29(16)19(28-18)24-14-5-6-14/h2-4,7-10,14H,5-6H2,1H3,(H2,23,24,26,28)(H2,25,27,30,31)/b15-8- HPDVKNQJQJLLCI-NVNXTCNLSA-N 219328 US9303033, B20, Table 37A, Compound 2 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219328 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219328&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335961 329994507 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383818 CC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccc(Cl)cc1 InChI=1S/C20H19ClN8O2/c1-10(11-2-4-13(21)5-3-11)23-18-26-16-12(8-15-17(30)27-20(31)25-15)9-22-29(16)19(28-18)24-14-6-7-14/h2-5,8-10,14H,6-7H2,1H3,(H2,23,24,26,28)(H2,25,27,30,31)/b15-8- XBLZKWARYFXIKW-NVNXTCNLSA-N 219329 US9303033, C20, Table 37A, Compound 3 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219329 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219329&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335795 329994508 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383819 Clc1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1Cl InChI=1S/C19H16Cl2N8O2/c20-12-4-1-9(5-13(12)21)7-22-17-26-15-10(6-14-16(30)27-19(31)25-14)8-23-29(15)18(28-17)24-11-2-3-11/h1,4-6,8,11H,2-3,7H2,(H2,22,24,26,28)(H2,25,27,30,31)/b14-6- VNEUBCMALCBPOJ-NSIKDUERSA-N 219330 US9303033, D20, Table 37A, Compound 4 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219330&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335987 329994509 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383820 CCC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1 InChI=1S/C21H22N8O2/c1-2-15(12-6-4-3-5-7-12)24-19-26-17-13(10-16-18(30)27-21(31)25-16)11-22-29(17)20(28-19)23-14-8-9-14/h3-7,10-11,14-15H,2,8-9H2,1H3,(H2,23,24,26,28)(H2,25,27,30,31)/b16-10- ROALQCJTIUWAEH-YBEGLDIGSA-N 219331 US9303033, E20, Table 37A, Compound 5 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219331 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219331&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335350 329994510 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383821 CN(C1CCOCC1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H22N8O3/c1-25(12-4-6-29-7-5-12)16-22-14-10(8-13-15(27)23-18(28)21-13)9-19-26(14)17(24-16)20-11-2-3-11/h8-9,11-12H,2-7H2,1H3,(H,20,22,24)(H2,21,23,27,28)/b13-8- HCMACRPMCKQDCA-JYRVWZFOSA-N 219332 US9303033, F20, Table 37A, Compound 6 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219332 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219332&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335797 329994511 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383822 Cc1cccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)n1 InChI=1S/C19H19N9O2/c1-10-3-2-4-13(22-10)9-20-17-25-15-11(7-14-16(29)26-19(30)24-14)8-21-28(15)18(27-17)23-12-5-6-12/h2-4,7-8,12H,5-6,9H2,1H3,(H2,20,23,25,27)(H2,24,26,29,30)/b14-7- RQBKGRVQOPZTBS-AUWJEWJLSA-N 219333 US9303033, G20, Table 37A, Compound 7 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219333 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219333&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335983 329994512 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383823 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3ccccn3)nc12 InChI=1S/C18H17N9O2/c28-15-13(23-18(29)25-15)7-10-8-21-27-14(10)24-16(26-17(27)22-11-4-5-11)20-9-12-3-1-2-6-19-12/h1-3,6-8,11H,4-5,9H2,(H2,20,22,24,26)(H2,23,25,28,29)/b13-7- HRWYDMNDZHWAHP-QPEQYQDCSA-N 219334 US9303033, H20, Table 37A, Compound 8 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219334 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219334&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335982 329994513 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383824 Cc1cnc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cn1 InChI=1S/C18H18N10O2/c1-9-5-20-12(7-19-9)8-21-16-25-14-10(4-13-15(29)26-18(30)24-13)6-22-28(14)17(27-16)23-11-2-3-11/h4-7,11H,2-3,8H2,1H3,(H2,21,23,25,27)(H2,24,26,29,30)/b13-4- UPUKOZRHYZIHOV-PQMHYQBVSA-N 219335 US9303033, I20, Table 37A, Compound 9 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219335 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219335&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335183 329994514 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383825 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3ccc(cc3)C#N)nc12 InChI=1S/C20H17N9O2/c21-8-11-1-3-12(4-2-11)9-22-18-26-16-13(7-15-17(30)27-20(31)25-15)10-23-29(16)19(28-18)24-14-5-6-14/h1-4,7,10,14H,5-6,9H2,(H2,22,24,26,28)(H2,25,27,30,31)/b15-7- XHUXICCBNOUWGB-CHHVJCJISA-N 219336 US9303033, J20, Table 37A, Compound 10 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219336 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219336&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336104 329994515 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383826 CC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1Cl InChI=1S/C20H19ClN8O2/c1-10(13-4-2-3-5-14(13)21)23-18-26-16-11(8-15-17(30)27-20(31)25-15)9-22-29(16)19(28-18)24-12-6-7-12/h2-5,8-10,12H,6-7H2,1H3,(H2,23,24,26,28)(H2,25,27,30,31)/b15-8- QBYHDBHMDWJNMS-NVNXTCNLSA-N 219337 US9303033, K20, Table 37A, Compound 11 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219337 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219337&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336081 329994516 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383827 COCC1(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)CCCC1 InChI=1S/C20H26N8O3/c1-31-11-20(6-2-3-7-20)10-21-17-25-15-12(8-14-16(29)26-19(30)24-14)9-22-28(15)18(27-17)23-13-4-5-13/h8-9,13H,2-7,10-11H2,1H3,(H2,21,23,25,27)(H2,24,26,29,30)/b14-8- NLBNBVJIQXWYCZ-ZSOIEALJSA-N 219338 US9303033, L20, Table 37A, Compound 12 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219338&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335599 329994517 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383828 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)N1CCCOCC1 InChI=1S/C17H20N8O3/c26-14-12(20-17(27)22-14)8-10-9-18-25-13(10)21-15(23-16(25)19-11-2-3-11)24-4-1-6-28-7-5-24/h8-9,11H,1-7H2,(H,19,21,23)(H2,20,22,26,27)/b12-8- BPTJNXXFFXLTRP-WQLSENKSSA-N 219339 US9303033, M20, Table 37A, Compound 13 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219339 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219339&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335345 329994518 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383829 OCCN1CCN(CC1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H23N9O3/c28-8-7-25-3-5-26(6-4-25)16-22-14-11(9-13-15(29)23-18(30)21-13)10-19-27(14)17(24-16)20-12-1-2-12/h9-10,12,28H,1-8H2,(H,20,22,24)(H2,21,23,29,30)/b13-9- UFYFSUHLRHHYKO-LCYFTJDESA-N 219340 US9303033, N20, Table 37A, Compound 14 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219340 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219340&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335160 329994519 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383830 C[C@H]1CN(C[C@@H](C)N1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H23N9O2/c1-9-7-26(8-10(2)20-9)16-23-14-11(5-13-15(28)24-18(29)22-13)6-19-27(14)17(25-16)21-12-3-4-12/h5-6,9-10,12,20H,3-4,7-8H2,1-2H3,(H,21,23,25)(H2,22,24,28,29)/b13-5-/t9-,10+ WIEASERILCJXTG-XNFJCXGQSA-N 219341 US9303033, O20, Table 37A, Compound 15 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219341&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335151 329994520 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383831 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NC3(CC3)c3ccccc3)nc12 InChI=1S/C21H20N8O2/c30-17-15(24-20(31)26-17)10-12-11-22-29-16(12)25-18(27-19(29)23-14-6-7-14)28-21(8-9-21)13-4-2-1-3-5-13/h1-5,10-11,14H,6-9H2,(H2,23,25,27,28)(H2,24,26,30,31)/b15-10- LRAGBPFJGMJTFT-GDNBJRDFSA-N 219342 US9303033, P20, Table 37A, Compound 16 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219342 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219342&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335604 329994521 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383832 Clc1ccccc1C1(CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H19ClN8O2/c22-14-4-2-1-3-13(14)21(7-8-21)29-18-26-16-11(9-15-17(31)27-20(32)25-15)10-23-30(16)19(28-18)24-12-5-6-12/h1-4,9-10,12H,5-8H2,(H2,24,26,28,29)(H2,25,27,31,32)/b15-9- KKGSMVSGFMFSSS-DHDCSXOGSA-N 219343 US9303033, Q20, Table 37A, Compound 17 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219343 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219343&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335605 329994522 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383833 Clc1cccc(c1)C1(CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H19ClN8O2/c22-13-3-1-2-12(9-13)21(6-7-21)29-18-26-16-11(8-15-17(31)27-20(32)25-15)10-23-30(16)19(28-18)24-14-4-5-14/h1-3,8-10,14H,4-7H2,(H2,24,26,28,29)(H2,25,27,31,32)/b15-8- VLHFTEZFKHAHKS-NVNXTCNLSA-N 219344 US9303033, R20, Table 37A, Compound 18 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219344&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336099 329994523 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383834 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3cnccn3)nc12 InChI=1S/C17H16N10O2/c28-14-12(23-17(29)25-14)5-9-6-21-27-13(9)24-15(26-16(27)22-10-1-2-10)20-8-11-7-18-3-4-19-11/h3-7,10H,1-2,8H2,(H2,20,22,24,26)(H2,23,25,28,29)/b12-5- CFHUUJKXRXOBTI-XGICHPGQSA-N 219345 US9303033, S20, Table 37A, Compound 19 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219345 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219345&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335166 329994524 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383835 C[C@@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1cccc(Cl)c1 InChI=1S/C20H19ClN8O2/c1-10(11-3-2-4-13(21)7-11)23-18-26-16-12(8-15-17(30)27-20(31)25-15)9-22-29(16)19(28-18)24-14-5-6-14/h2-4,7-10,14H,5-6H2,1H3,(H2,23,24,26,28)(H2,25,27,30,31)/b15-8-/t10-/m1/s1 ROWOHQPHJFJFOF-IIBSKXHVSA-N 219346 US9303033, T20, Table 37A, Compound 20 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219346&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335986 329994525 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383836 C[C@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1cccc(Cl)c1 InChI=1S/C20H19ClN8O2/c1-10(11-3-2-4-13(21)7-11)23-18-26-16-12(8-15-17(30)27-20(31)25-15)9-22-29(16)19(28-18)24-14-5-6-14/h2-4,7-10,14H,5-6H2,1H3,(H2,23,24,26,28)(H2,25,27,30,31)/b15-8-/t10-/m0/s1 ROWOHQPHJFJFOF-SOOGHKCXSA-N 219347 US9303033, U20, Table 37A, Compound 21 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219347&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335798 329994526 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383837 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)N1CCS(=O)(=O)CC1 InChI=1S/C16H18N8O4S/c25-13-11(19-16(26)21-13)7-9-8-17-24-12(9)20-14(22-15(24)18-10-1-2-10)23-3-5-29(27,28)6-4-23/h7-8,10H,1-6H2,(H,18,20,22)(H2,19,21,25,26)/b11-7- FBZZMMUDBVXECL-XFFZJAGNSA-N 219348 US9303033, V20, Table 37A, Compound 22 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219348 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219348&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335793 329994527 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383838 CCOCC1(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)CC1 InChI=1S/C19H24N8O3/c1-2-30-10-19(5-6-19)9-20-16-24-14-11(7-13-15(28)25-18(29)23-13)8-21-27(14)17(26-16)22-12-3-4-12/h7-8,12H,2-6,9-10H2,1H3,(H2,20,22,24,26)(H2,23,25,28,29)/b13-7- FUSDKQKBFTYELD-QPEQYQDCSA-N 219349 US9303033, W20, Table 37A, Compound 23 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219349&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336103 329994528 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383839 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCC3(CN4CCOCC4)CC3)nc12 InChI=1S/C21H27N9O3/c31-17-15(25-20(32)27-17)9-13-10-23-30-16(13)26-18(28-19(30)24-14-1-2-14)22-11-21(3-4-21)12-29-5-7-33-8-6-29/h9-10,14H,1-8,11-12H2,(H2,22,24,26,28)(H2,25,27,31,32)/b15-9- LDSYBLNRDRBJID-DHDCSXOGSA-N 219350 US9303033, X20, Table 37A, Compound 24 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219350&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335603 329994529 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383840 COCCNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C15H18N8O3/c1-26-5-4-16-13-20-11-8(6-10-12(24)21-15(25)19-10)7-17-23(11)14(22-13)18-9-2-3-9/h6-7,9H,2-5H2,1H3,(H2,16,18,20,22)(H2,19,21,24,25)/b10-6- CJAAXYSKNQMLDK-POHAHGRESA-N 219351 US9303033, Y20, Table 37A, Compound 25 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219351&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335612 329994530 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383841 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCC3(CN4CCCC4)CC3)nc12 InChI=1S/C21H27N9O2/c31-17-15(25-20(32)27-17)9-13-10-23-30-16(13)26-18(28-19(30)24-14-3-4-14)22-11-21(5-6-21)12-29-7-1-2-8-29/h9-10,14H,1-8,11-12H2,(H2,22,24,26,28)(H2,25,27,31,32)/b15-9- PPVCLGQHDBHXTC-DHDCSXOGSA-N 219352 US9303033, A21, Table 37A, Compound 26 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219352 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219352&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335608 329994531 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383842 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCC3(Cn4ccnc4)CC3)nc12 InChI=1S/C20H22N10O2/c31-16-14(25-19(32)27-16)7-12-8-23-30-15(12)26-17(28-18(30)24-13-1-2-13)22-9-20(3-4-20)10-29-6-5-21-11-29/h5-8,11,13H,1-4,9-10H2,(H2,22,24,26,28)(H2,25,27,31,32)/b14-7- GNPXMVASTYGCLH-AUWJEWJLSA-N 219353 US9303033, B21, Table 37A, Compound 27 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219353&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336102 329994532 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383843 CN1CCN(CC2(CNc3nc(NC4CC4)n4ncc(\C=C5/NC(=O)NC5=O)c4n3)CC2)CC1 InChI=1S/C22H30N10O2/c1-30-6-8-31(9-7-30)13-22(4-5-22)12-23-19-27-17-14(10-16-18(33)28-21(34)26-16)11-24-32(17)20(29-19)25-15-2-3-15/h10-11,15H,2-9,12-13H2,1H3,(H2,23,25,27,29)(H2,26,28,33,34)/b16-10- JWQHPVDBWZCUBG-YBEGLDIGSA-N 219354 US9303033, C21, Table 37A, Compound 28 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219354 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219354&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335992 329994533 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383844 CS(=O)(=O)c1cccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C20H20N8O4S/c1-33(31,32)14-4-2-3-11(7-14)9-21-18-25-16-12(8-15-17(29)26-20(30)24-15)10-22-28(16)19(27-18)23-13-5-6-13/h2-4,7-8,10,13H,5-6,9H2,1H3,(H2,21,23,25,27)(H2,24,26,29,30)/b15-8- AMPPUCSYHWHYQN-NVNXTCNLSA-N 219355 US9303033, D21, Table 37A, Compound 29 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219355 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219355&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336107 329994534 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383845 Cc1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1C InChI=1S/C21H22N8O2/c1-11-3-4-13(7-12(11)2)9-22-19-26-17-14(8-16-18(30)27-21(31)25-16)10-23-29(17)20(28-19)24-15-5-6-15/h3-4,7-8,10,15H,5-6,9H2,1-2H3,(H2,22,24,26,28)(H2,25,27,30,31)/b16-8- JAUABHCOAFHKDR-PXNMLYILSA-N 219356 US9303033, E21, Table 37A, Compound 30 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219356&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67254931 329994535 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383846 CN1CCN(CC(Nc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c2ccccc2)CC1 InChI=1S/C25H30N10O2/c1-33-9-11-34(12-10-33)15-20(16-5-3-2-4-6-16)28-23-30-21-17(13-19-22(36)31-25(37)29-19)14-26-35(21)24(32-23)27-18-7-8-18/h2-6,13-14,18,20H,7-12,15H2,1H3,(H2,27,28,30,32)(H2,29,31,36,37)/b19-13- STANIIKAVHQBSR-UYRXBGFRSA-N 219357 US9303033, F21, Table 37A, Compound 31 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219357 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219357&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89888232 329994536 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383847 Cc1c(Cl)cccc1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H19ClN8O2/c1-10-11(3-2-4-14(10)21)8-22-18-26-16-12(7-15-17(30)27-20(31)25-15)9-23-29(16)19(28-18)24-13-5-6-13/h2-4,7,9,13H,5-6,8H2,1H3,(H2,22,24,26,28)(H2,25,27,30,31)/b15-7- URASXWJJLDIUQH-CHHVJCJISA-N 219358 US9303033, G21, Table 37A, Compound 32 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219358 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219358&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335800 329994537 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383848 Cc1ccc(F)c(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1F InChI=1S/C20H18F2N8O2/c1-9-2-5-13(21)12(15(9)22)8-23-18-27-16-10(6-14-17(31)28-20(32)26-14)7-24-30(16)19(29-18)25-11-3-4-11/h2,5-7,11H,3-4,8H2,1H3,(H2,23,25,27,29)(H2,26,28,31,32)/b14-6- PPZBWYWBQVRLMS-NSIKDUERSA-N 219359 US9303033, H21, Table 37A, Compound 33 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219359 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219359&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336111 329994538 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383849 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NC(CN3CCOCC3)c3ccccc3)nc12 InChI=1S/C24H27N9O3/c34-21-18(28-24(35)30-21)12-16-13-25-33-20(16)29-22(31-23(33)26-17-6-7-17)27-19(15-4-2-1-3-5-15)14-32-8-10-36-11-9-32/h1-5,12-13,17,19H,6-11,14H2,(H2,26,27,29,31)(H2,28,30,34,35)/b18-12- KLQNEFINHZOVLT-PDGQHHTCSA-N 219360 US9303033, I21, Table 37A, Compound 34 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219360&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335347 329994539 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383850 Cn1ccnc1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C17H18N10O2/c1-26-5-4-18-12(26)8-19-15-23-13-9(6-11-14(28)24-17(29)22-11)7-20-27(13)16(25-15)21-10-2-3-10/h4-7,10H,2-3,8H2,1H3,(H2,19,21,23,25)(H2,22,24,28,29)/b11-6- OEIDCIWNLCIEMM-WDZFZDKYSA-N 219361 US9303033, J21, Table 37A, Compound 35 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219361 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219361&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336105 329994540 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383851 CC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1F InChI=1S/C20H19FN8O2/c1-10(13-4-2-3-5-14(13)21)23-18-26-16-11(8-15-17(30)27-20(31)25-15)9-22-29(16)19(28-18)24-12-6-7-12/h2-5,8-10,12H,6-7H2,1H3,(H2,23,24,26,28)(H2,25,27,30,31)/b15-8- MCNLPDKUXNUBNL-NVNXTCNLSA-N 219362 US9303033, K21, Table 37A, Compound 36 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219362 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219362&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335804 329994541 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383852 Cc1ccc(Cl)cc1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H19ClN8O2/c1-10-2-3-13(21)6-11(10)8-22-18-26-16-12(7-15-17(30)27-20(31)25-15)9-23-29(16)19(28-18)24-14-4-5-14/h2-3,6-7,9,14H,4-5,8H2,1H3,(H2,22,24,26,28)(H2,25,27,30,31)/b15-7- NICDSMZUABDWFI-CHHVJCJISA-N 219363 US9303033, L21, Table 37A, Compound 37 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219363 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219363&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335616 329994542 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383853 Cc1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1F InChI=1S/C20H19FN8O2/c1-10-2-3-11(6-14(10)21)8-22-18-26-16-12(7-15-17(30)27-20(31)25-15)9-23-29(16)19(28-18)24-13-4-5-13/h2-3,6-7,9,13H,4-5,8H2,1H3,(H2,22,24,26,28)(H2,25,27,30,31)/b15-7- OWHSNMKOOPPCHE-CHHVJCJISA-N 219364 US9303033, M21, Table 37A, Compound 38 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219364 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219364&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335985 329994543 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383854 Fc1c(Cl)cccc1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H16ClFN8O2/c20-12-3-1-2-9(14(12)21)7-22-17-26-15-10(6-13-16(30)27-19(31)25-13)8-23-29(15)18(28-17)24-11-4-5-11/h1-3,6,8,11H,4-5,7H2,(H2,22,24,26,28)(H2,25,27,30,31)/b13-6- YUFITCPMMQELIW-MLPAPPSSSA-N 219365 US9303033, N21, Table 37A, Compound 39 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219365 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219365&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313799 329994544 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383855 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(N[C@@H]3CCc4ccccc34)nc12 InChI=1S/C21H20N8O2/c30-18-16(25-21(31)27-18)9-12-10-22-29-17(12)26-19(28-20(29)23-13-6-7-13)24-15-8-5-11-3-1-2-4-14(11)15/h1-4,9-10,13,15H,5-8H2,(H2,23,24,26,28)(H2,25,27,30,31)/b16-9-/t15-/m1/s1 OXDPWRLJMBDTDO-AVIKPIRVSA-N 219366 US9303033, O21, Table 37A, Compound 40 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219366 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219366&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335806 329994545 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383856 Cc1cc(C)cc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C21H22N8O2/c1-11-5-12(2)7-13(6-11)9-22-19-26-17-14(8-16-18(30)27-21(31)25-16)10-23-29(17)20(28-19)24-15-3-4-15/h5-8,10,15H,3-4,9H2,1-2H3,(H2,22,24,26,28)(H2,25,27,30,31)/b16-8- FLSGVUYWNLYLFL-PXNMLYILSA-N 219367 US9303033, P21, Table 37A, Compound 41 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219367 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219367&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89888129 329994546 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383857 Cn1ccc2c(CNc3nc(NC4CC4)n4ncc(\C=C5/NC(=O)NC5=O)c4n3)cccc12 InChI=1S/C22H21N9O2/c1-30-8-7-15-12(3-2-4-17(15)30)10-23-20-27-18-13(9-16-19(32)28-22(33)26-16)11-24-31(18)21(29-20)25-14-5-6-14/h2-4,7-9,11,14H,5-6,10H2,1H3,(H2,23,25,27,29)(H2,26,28,32,33)/b16-9- SSSCSRQIUMAAGE-SXGWCWSVSA-N 219368 US9303033, Q21, Table 37A, Compound 42 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219368 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219368&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335609 329994547 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383858 CN(C)CCOc1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C23H27N9O3/c1-31(2)9-10-35-17-7-3-14(4-8-17)12-24-21-28-19-15(11-18-20(33)29-23(34)27-18)13-25-32(19)22(30-21)26-16-5-6-16/h3-4,7-8,11,13,16H,5-6,9-10,12H2,1-2H3,(H2,24,26,28,30)(H2,27,29,33,34)/b18-11- OGXYNCZMZNPLPU-WQRHYEAKSA-N 219369 US9303033, R21, Table 37A, Compound 43 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219369&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336110 329994548 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383859 Cn1cc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cn1 InChI=1S/C17H18N10O2/c1-26-8-9(6-19-26)5-18-15-23-13-10(4-12-14(28)24-17(29)22-12)7-20-27(13)16(25-15)21-11-2-3-11/h4,6-8,11H,2-3,5H2,1H3,(H2,18,21,23,25)(H2,22,24,28,29)/b12-4- AWKDPSKAORFMEK-QCDXTXTGSA-N 219370 US9303033, S21, Table 37A, Compound 44 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219370 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219370&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89888156 329994549 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383860 Cc1cc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)ccc1F InChI=1S/C20H19FN8O2/c1-10-6-11(2-5-14(10)21)8-22-18-26-16-12(7-15-17(30)27-20(31)25-15)9-23-29(16)19(28-18)24-13-3-4-13/h2,5-7,9,13H,3-4,8H2,1H3,(H2,22,24,26,28)(H2,25,27,30,31)/b15-7- CGUHBTMYWKUACE-CHHVJCJISA-N 219371 US9303033, T21, Table 37A, Compound 45 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219371 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219371&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335802 329994550 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383861 CC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccc2OCOc2c1 InChI=1S/C21H20N8O4/c1-10(11-2-5-15-16(7-11)33-9-32-15)23-19-26-17-12(6-14-18(30)27-21(31)25-14)8-22-29(17)20(28-19)24-13-3-4-13/h2,5-8,10,13H,3-4,9H2,1H3,(H2,23,24,26,28)(H2,25,27,30,31)/b14-6- INLSUMDDLYPPBQ-NSIKDUERSA-N 219372 US9303033, U21, Table 37A, Compound 46 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219372 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219372&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313940 329994551 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383862 Cc1ccc(F)c(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1Cl InChI=1S/C20H18ClFN8O2/c1-9-2-5-13(22)12(15(9)21)8-23-18-27-16-10(6-14-17(31)28-20(32)26-14)7-24-30(16)19(29-18)25-11-3-4-11/h2,5-7,11H,3-4,8H2,1H3,(H2,23,25,27,29)(H2,26,28,31,32)/b14-6- UZMXJJISGZYJFU-NSIKDUERSA-N 219373 US9303033, V21, Table 37A, Compound 47 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219373 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219373&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314175 329994552 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383863 CC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1cc(F)cc(F)c1 InChI=1S/C20H18F2N8O2/c1-9(10-4-12(21)7-13(22)5-10)24-18-27-16-11(6-15-17(31)28-20(32)26-15)8-23-30(16)19(29-18)25-14-2-3-14/h4-9,14H,2-3H2,1H3,(H2,24,25,27,29)(H2,26,28,31,32)/b15-6- PTEQKQJHVDUVQN-UUASQNMZSA-N 219374 US9303033, W21, Table 37A, Compound 48 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219374 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219374&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335995 329994553 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383864 FC(F)(F)Oc1cccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C20H17F3N8O3/c21-20(22,23)34-13-3-1-2-10(6-13)8-24-17-28-15-11(7-14-16(32)29-19(33)27-14)9-25-31(15)18(30-17)26-12-4-5-12/h1-3,6-7,9,12H,4-5,8H2,(H2,24,26,28,30)(H2,27,29,32,33)/b14-7- NKXGZUDAVUIAAH-AUWJEWJLSA-N 219375 US9303033, X21, Table 37A, Compound 49 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219375 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219375&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335363 329994554 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383865 Cc1ccc(Cl)c(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1F InChI=1S/C20H18ClFN8O2/c1-9-2-5-13(21)12(15(9)22)8-23-18-27-16-10(6-14-17(31)28-20(32)26-14)7-24-30(16)19(29-18)25-11-3-4-11/h2,5-7,11H,3-4,8H2,1H3,(H2,23,25,27,29)(H2,26,28,31,32)/b14-6- MPRKPUPDOIDBLG-NSIKDUERSA-N 219376 US9303033, Y21, Table 37A, Compound 50 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219376 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219376&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314753 329994555 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383866 Cn1c(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)nc2ccccc12 InChI=1S/C21H20N10O2/c1-30-15-5-3-2-4-13(15)25-16(30)10-22-19-27-17-11(8-14-18(32)28-21(33)26-14)9-23-31(17)20(29-19)24-12-6-7-12/h2-5,8-9,12H,6-7,10H2,1H3,(H2,22,24,27,29)(H2,26,28,32,33)/b14-8- YUXWLNINYWGZAN-ZSOIEALJSA-N 219377 US9303033, Z21, Table 37A, Compound 51 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219377 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219377&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335614 329994556 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383867 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3ccccc3N3CCOCC3)nc12 InChI=1S/C23H25N9O3/c33-20-17(27-23(34)29-20)11-15-13-25-32-19(15)28-21(30-22(32)26-16-5-6-16)24-12-14-3-1-2-4-18(14)31-7-9-35-10-8-31/h1-4,11,13,16H,5-10,12H2,(H2,24,26,28,30)(H2,27,29,33,34)/b17-11- DKFMCHQICTWLRQ-BOPFTXTBSA-N 219378 US9303033, A22, Table 37A, Compound 52 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219378 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219378&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335611 329994557 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383868 Clc1cc(Cl)cc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C19H16Cl2N8O2/c20-11-3-9(4-12(21)6-11)7-22-17-26-15-10(5-14-16(30)27-19(31)25-14)8-23-29(15)18(28-17)24-13-1-2-13/h3-6,8,13H,1-2,7H2,(H2,22,24,26,28)(H2,25,27,30,31)/b14-5- UKZMVZHLDMARDT-RZNTYIFUSA-N 219379 US9303033, B22, Table 37A, Compound 53 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219379 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219379&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335981 329994558 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383869 Fc1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1Cl InChI=1S/C19H16ClFN8O2/c20-12-5-9(1-4-13(12)21)7-22-17-26-15-10(6-14-16(30)27-19(31)25-14)8-23-29(15)18(28-17)24-11-2-3-11/h1,4-6,8,11H,2-3,7H2,(H2,22,24,26,28)(H2,25,27,30,31)/b14-6- NAAFTAWZXKBTBD-NSIKDUERSA-N 219380 US9303033, C22, Table 37A, Compound 54 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219380 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219380&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 71114384 329994559 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383870 Fc1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c(Cl)c1 InChI=1S/C19H16ClFN8O2/c20-13-6-11(21)2-1-9(13)7-22-17-26-15-10(5-14-16(30)27-19(31)25-14)8-23-29(15)18(28-17)24-12-3-4-12/h1-2,5-6,8,12H,3-4,7H2,(H2,22,24,26,28)(H2,25,27,30,31)/b14-5- DZLJNSSRQVYINP-RZNTYIFUSA-N 219381 US9303033, D22, Table 37A, Compound 55 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219381 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219381&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335994 329994560 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383871 Cc1cc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)no1 InChI=1S/C17H17N9O3/c1-8-4-11(25-29-8)7-18-15-22-13-9(5-12-14(27)23-17(28)21-12)6-19-26(13)16(24-15)20-10-2-3-10/h4-6,10H,2-3,7H2,1H3,(H2,18,20,22,24)(H2,21,23,27,28)/b12-5- JABYGUKWMVUZCX-XGICHPGQSA-N 219382 US9303033, E22, Table 37A, Compound 56 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219382 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219382&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336100 329994561 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383872 Cc1csc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C18H18N8O2S/c1-9-4-12(29-8-9)7-19-16-23-14-10(5-13-15(27)24-18(28)22-13)6-20-26(14)17(25-16)21-11-2-3-11/h4-6,8,11H,2-3,7H2,1H3,(H2,19,21,23,25)(H2,22,24,27,28)/b13-5- FFEDEIBQJPVWOP-ACAGNQJTSA-N 219383 US9303033, F22, Table 37A, Compound 57 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219383 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219383&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336109 329994562 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383873 Brc1ccccc1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H17BrN8O2/c20-13-4-2-1-3-10(13)8-21-17-25-15-11(7-14-16(29)26-19(30)24-14)9-22-28(15)18(27-17)23-12-5-6-12/h1-4,7,9,12H,5-6,8H2,(H2,21,23,25,27)(H2,24,26,29,30)/b14-7- FKMGRNJUACTPOT-AUWJEWJLSA-N 219384 US9303033, G22, Table 37A, Compound 58 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219384 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219384&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335233 329994563 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383874 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3nccs3)nc12 InChI=1S/C16H15N9O2S/c26-13-10(21-16(27)23-13)5-8-6-19-25-12(8)22-14(18-7-11-17-3-4-28-11)24-15(25)20-9-1-2-9/h3-6,9H,1-2,7H2,(H2,18,20,22,24)(H2,21,23,26,27)/b10-5- OIVNGMFAALMIET-YHYXMXQVSA-N 219385 US9303033, H22, Table 37A, Compound 59 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219385 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219385&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335807 329994564 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383875 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3ccsc3)nc12 InChI=1S/C17H16N8O2S/c26-14-12(21-17(27)23-14)5-10-7-19-25-13(10)22-15(18-6-9-3-4-28-8-9)24-16(25)20-11-1-2-11/h3-5,7-8,11H,1-2,6H2,(H2,18,20,22,24)(H2,21,23,26,27)/b12-5- WVPUNKQNWABOSD-XGICHPGQSA-N 219386 US9303033, I22, Table 37A, Compound 60 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219386 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219386&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335997 329994565 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383876 COc1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1Cl InChI=1S/C20H19ClN8O3/c1-32-15-5-2-10(6-13(15)21)8-22-18-26-16-11(7-14-17(30)27-20(31)25-14)9-23-29(16)19(28-18)24-12-3-4-12/h2,5-7,9,12H,3-4,8H2,1H3,(H2,22,24,26,28)(H2,25,27,30,31)/b14-7- DVLKKMJYFVPYPW-AUWJEWJLSA-N 219387 US9303033, J22, Table 37A, Compound 61 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219387 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219387&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89888220 329994566 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383877 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3cc4ccccc4s3)nc12 InChI=1S/C21H18N8O2S/c30-18-15(25-21(31)27-18)8-12-9-23-29-17(12)26-19(28-20(29)24-13-5-6-13)22-10-14-7-11-3-1-2-4-16(11)32-14/h1-4,7-9,13H,5-6,10H2,(H2,22,24,26,28)(H2,25,27,30,31)/b15-8- LCJZWVJCXIDSTG-NVNXTCNLSA-N 219388 US9303033, K22, Table 37A, Compound 62 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219388 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219388&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336007 329994567 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383878 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NC3CCCc4ccccc34)nc12 InChI=1S/C22H22N8O2/c31-19-17(26-22(32)28-19)10-13-11-23-30-18(13)27-20(29-21(30)24-14-8-9-14)25-16-7-3-5-12-4-1-2-6-15(12)16/h1-2,4,6,10-11,14,16H,3,5,7-9H2,(H2,24,25,27,29)(H2,26,28,31,32)/b17-10- VIHPHOJREHWUNF-YVLHZVERSA-N 219389 US9303033, L22, Table 37A, Compound 63 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219389 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219389&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335178 329994568 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383879 CC[C@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1 InChI=1S/C21H22N8O2/c1-2-15(12-6-4-3-5-7-12)24-19-26-17-13(10-16-18(30)27-21(31)25-16)11-22-29(17)20(28-19)23-14-8-9-14/h3-7,10-11,14-15H,2,8-9H2,1H3,(H2,23,24,26,28)(H2,25,27,30,31)/b16-10-/t15-/m0/s1 ROALQCJTIUWAEH-HEUOVEHFSA-N 219390 US9303033, M22, Table 37A, Compound 64 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219390 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219390&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335172 329994569 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383880 Cn1cnc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C17H18N10O2/c1-26-7-11(19-8-26)6-18-15-23-13-9(4-12-14(28)24-17(29)22-12)5-20-27(13)16(25-15)21-10-2-3-10/h4-5,7-8,10H,2-3,6H2,1H3,(H2,18,21,23,25)(H2,22,24,28,29)/b12-4- BTIFBURGLVMGMV-QCDXTXTGSA-N 219391 US9303033, N22, Table 37A, Compound 65 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219391 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219391&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335811 329994570 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383881 Cc1cccc(Cl)c1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H19ClN8O2/c1-10-3-2-4-14(21)13(10)9-22-18-26-16-11(7-15-17(30)27-20(31)25-15)8-23-29(16)19(28-18)24-12-5-6-12/h2-4,7-8,12H,5-6,9H2,1H3,(H2,22,24,26,28)(H2,25,27,30,31)/b15-7- OKCXSDIOWHVHRP-CHHVJCJISA-N 219392 US9303033, O22, Table 37A, Compound 66 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219392 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219392&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335361 329994571 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383882 Fc1cccc(F)c1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H16F2N8O2/c20-12-2-1-3-13(21)11(12)8-22-17-26-15-9(6-14-16(30)27-19(31)25-14)7-23-29(15)18(28-17)24-10-4-5-10/h1-3,6-7,10H,4-5,8H2,(H2,22,24,26,28)(H2,25,27,30,31)/b14-6- BWBZPWQKFLHSHP-NSIKDUERSA-N 219393 US9303033, P22, Table 37A, Compound 67 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219393&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335362 329994572 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383883 Cc1ccc(C)c(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C21H22N8O2/c1-11-3-4-12(2)13(7-11)9-22-19-26-17-14(8-16-18(30)27-21(31)25-16)10-23-29(17)20(28-19)24-15-5-6-15/h3-4,7-8,10,15H,5-6,9H2,1-2H3,(H2,22,24,26,28)(H2,25,27,30,31)/b16-8- DJHFGHZTRZUICE-PXNMLYILSA-N 219394 US9303033, Q22, Table 37A, Compound 68 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219394 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219394&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89887973 329994573 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383884 FC(F)(F)Oc1ccccc1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H17F3N8O3/c21-20(22,23)34-14-4-2-1-3-10(14)8-24-17-28-15-11(7-13-16(32)29-19(33)27-13)9-25-31(15)18(30-17)26-12-5-6-12/h1-4,7,9,12H,5-6,8H2,(H2,24,26,28,30)(H2,27,29,32,33)/b13-7- PLPUWLOAUIDOSH-QPEQYQDCSA-N 219395 US9303033, R22, Table 37A, Compound 69 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219395 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219395&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335607 329994574 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383885 Fc1cccc(Cl)c1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H16ClFN8O2/c20-12-2-1-3-13(21)11(12)8-22-17-26-15-9(6-14-16(30)27-19(31)25-14)7-23-29(15)18(28-17)24-10-4-5-10/h1-3,6-7,10H,4-5,8H2,(H2,22,24,26,28)(H2,25,27,30,31)/b14-6- RCUIYBFAYLBDRM-NSIKDUERSA-N 219396 US9303033, S22, Table 37A, Compound 70 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219396 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219396&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89888154 329994575 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383886 FC(F)(F)c1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C20H17F3N8O2/c21-20(22,23)12-3-1-10(2-4-12)8-24-17-28-15-11(7-14-16(32)29-19(33)27-14)9-25-31(15)18(30-17)26-13-5-6-13/h1-4,7,9,13H,5-6,8H2,(H2,24,26,28,30)(H2,27,29,32,33)/b14-7- WRISEUCWOOLVGQ-AUWJEWJLSA-N 219397 US9303033, T22, Table 37A, Compound 71 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219397&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335366 329994576 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383887 FC(F)(F)c1ccccc1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H17F3N8O2/c21-20(22,23)13-4-2-1-3-10(13)8-24-17-28-15-11(7-14-16(32)29-19(33)27-14)9-25-31(15)18(30-17)26-12-5-6-12/h1-4,7,9,12H,5-6,8H2,(H2,24,26,28,30)(H2,27,29,32,33)/b14-7- ODJVPQVEZLDGIB-AUWJEWJLSA-N 219398 US9303033, U22, Table 37A, Compound 72 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219398&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335365 329994577 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383888 Cc1cccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C20H20N8O2/c1-11-3-2-4-12(7-11)9-21-18-25-16-13(8-15-17(29)26-20(30)24-15)10-22-28(16)19(27-18)23-14-5-6-14/h2-4,7-8,10,14H,5-6,9H2,1H3,(H2,21,23,25,27)(H2,24,26,29,30)/b15-8- JBHGRNSFKJAPNG-NVNXTCNLSA-N 219399 US9303033, V22, Table 37A, Compound 73 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219399 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219399&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335177 329994578 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383889 Clc1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cn1 InChI=1S/C18H16ClN9O2/c19-13-4-1-9(6-20-13)7-21-16-25-14-10(5-12-15(29)26-18(30)24-12)8-22-28(14)17(27-16)23-11-2-3-11/h1,4-6,8,11H,2-3,7H2,(H2,21,23,25,27)(H2,24,26,29,30)/b12-5- MJPBZUYTZIPIGM-XGICHPGQSA-N 219400 US9303033, W22, Table 37A, Compound 74 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219400 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219400&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 88941274 329994579 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383890 COc1cccc(OC)c1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H22N8O4/c1-32-15-4-3-5-16(33-2)13(15)10-22-19-26-17-11(8-14-18(30)27-21(31)25-14)9-23-29(17)20(28-19)24-12-6-7-12/h3-5,8-9,12H,6-7,10H2,1-2H3,(H2,22,24,26,28)(H2,25,27,30,31)/b14-8- KWYKTPRLIQNIHG-ZSOIEALJSA-N 219401 US9303033, X22, Table 37A, Compound 75 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219401 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219401&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336002 329994580 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383891 Clc1cccc(Cl)c1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H16Cl2N8O2/c20-12-2-1-3-13(21)11(12)8-22-17-26-15-9(6-14-16(30)27-19(31)25-14)7-23-29(15)18(28-17)24-10-4-5-10/h1-3,6-7,10H,4-5,8H2,(H2,22,24,26,28)(H2,25,27,30,31)/b14-6- VEYSXMVRFYYSGZ-NSIKDUERSA-N 219402 US9303033, Y22, Table 37A, Compound 76 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219402 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219402&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89888208 329994581 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383892 Fc1c(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cccc1C(F)(F)F InChI=1S/C20H16F4N8O2/c21-14-9(2-1-3-12(14)20(22,23)24)7-25-17-29-15-10(6-13-16(33)30-19(34)28-13)8-26-32(15)18(31-17)27-11-4-5-11/h1-3,6,8,11H,4-5,7H2,(H2,25,27,29,31)(H2,28,30,33,34)/b13-6- HOIJQZKSZKQOHY-MLPAPPSSSA-N 219403 US9303033, Z22, Table 37A, Compound 77 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219403 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219403&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335368 329994582 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383893 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3cccc(CN4CCOCC4)c3)nc12 InChI=1S/C24H27N9O3/c34-21-19(28-24(35)30-21)11-17-13-26-33-20(17)29-22(31-23(33)27-18-4-5-18)25-12-15-2-1-3-16(10-15)14-32-6-8-36-9-7-32/h1-3,10-11,13,18H,4-9,12,14H2,(H2,25,27,29,31)(H2,28,30,34,35)/b19-11- GYTPHZVUEZGYOC-ODLFYWEKSA-N 219404 US9303033, A23, Table 37A, Compound 78 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219404 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219404&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336003 329994583 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383894 Cn1cncc1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C17H18N10O2/c1-26-8-18-6-11(26)7-19-15-23-13-9(4-12-14(28)24-17(29)22-12)5-20-27(13)16(25-15)21-10-2-3-10/h4-6,8,10H,2-3,7H2,1H3,(H2,19,21,23,25)(H2,22,24,28,29)/b12-4- PUGGVSYJELKFGJ-QCDXTXTGSA-N 219405 US9303033, B23, Table 37A, Compound 79 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219405 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219405&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335235 329994584 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383895 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3cccs3)nc12 InChI=1S/C17H16N8O2S/c26-14-12(21-17(27)23-14)6-9-7-19-25-13(9)22-15(18-8-11-2-1-5-28-11)24-16(25)20-10-3-4-10/h1-2,5-7,10H,3-4,8H2,(H2,18,20,22,24)(H2,21,23,26,27)/b12-6- LRVADDUDZKOFSQ-SDQBBNPISA-N 219406 US9303033, C23, Table 37A, Compound 80 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219406 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219406&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335193 329994585 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383896 Clc1cccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1Cl InChI=1S/C19H16Cl2N8O2/c20-12-3-1-2-9(14(12)21)7-22-17-26-15-10(6-13-16(30)27-19(31)25-13)8-23-29(15)18(28-17)24-11-4-5-11/h1-3,6,8,11H,4-5,7H2,(H2,22,24,26,28)(H2,25,27,30,31)/b13-6- WUDLMVOGZVTKDQ-MLPAPPSSSA-N 219407 US9303033, D23, Table 37A, Compound 81 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219407 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219407&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89887988 329994586 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383897 COc1cccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1OC InChI=1S/C21H22N8O4/c1-32-15-5-3-4-11(16(15)33-2)9-22-19-26-17-12(8-14-18(30)27-21(31)25-14)10-23-29(17)20(28-19)24-13-6-7-13/h3-5,8,10,13H,6-7,9H2,1-2H3,(H2,22,24,26,28)(H2,25,27,30,31)/b14-8- JQHQXGRTVOEKRE-ZSOIEALJSA-N 219408 US9303033, E23, Table 37A, Compound 82 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219408 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219408&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335801 329994587 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383898 Cc1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C20H20N8O2/c1-11-2-4-12(5-3-11)9-21-18-25-16-13(8-15-17(29)26-20(30)24-15)10-22-28(16)19(27-18)23-14-6-7-14/h2-5,8,10,14H,6-7,9H2,1H3,(H2,21,23,25,27)(H2,24,26,29,30)/b15-8- DXTHCSUGVMKVAG-NVNXTCNLSA-N 219409 US9303033, F23, Table 37A, Compound 83 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219409 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219409&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335817 329994588 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383899 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3ccc4OCOc4c3)nc12 InChI=1S/C20H18N8O4/c29-17-13(24-20(30)26-17)6-11-8-22-28-16(11)25-18(27-19(28)23-12-2-3-12)21-7-10-1-4-14-15(5-10)32-9-31-14/h1,4-6,8,12H,2-3,7,9H2,(H2,21,23,25,27)(H2,24,26,29,30)/b13-6- FJHDUTXZDXMWNM-MLPAPPSSSA-N 219410 US9303033, G23, Table 37A, Compound 84 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219410 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219410&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335618 329994589 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383900 Fc1cccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1F InChI=1S/C19H16F2N8O2/c20-12-3-1-2-9(14(12)21)7-22-17-26-15-10(6-13-16(30)27-19(31)25-13)8-23-29(15)18(28-17)24-11-4-5-11/h1-3,6,8,11H,4-5,7H2,(H2,22,24,26,28)(H2,25,27,30,31)/b13-6- XVGMWGAUIXKGNS-MLPAPPSSSA-N 219411 US9303033, H23, Table 37A, Compound 85 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219411 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219411&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335815 329994590 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383901 Fc1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c(F)c1 InChI=1S/C19H16F2N8O2/c20-11-2-1-9(13(21)6-11)7-22-17-26-15-10(5-14-16(30)27-19(31)25-14)8-23-29(15)18(28-17)24-12-3-4-12/h1-2,5-6,8,12H,3-4,7H2,(H2,22,24,26,28)(H2,25,27,30,31)/b14-5- OAIZOZZKJIRTFP-RZNTYIFUSA-N 219412 US9303033, I23, Table 37A, Compound 86 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219412 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219412&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336118 329994591 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383902 Fc1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1F InChI=1S/C19H16F2N8O2/c20-12-4-1-9(5-13(12)21)7-22-17-26-15-10(6-14-16(30)27-19(31)25-14)8-23-29(15)18(28-17)24-11-2-3-11/h1,4-6,8,11H,2-3,7H2,(H2,22,24,26,28)(H2,25,27,30,31)/b14-6- WSBHAFUKNNHTOD-NSIKDUERSA-N 219413 US9303033, J23, Table 37A, Compound 87 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219413 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219413&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336113 329994592 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383903 Cc1ccccc1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H20N8O2/c1-11-4-2-3-5-12(11)9-21-18-25-16-13(8-15-17(29)26-20(30)24-15)10-22-28(16)19(27-18)23-14-6-7-14/h2-5,8,10,14H,6-7,9H2,1H3,(H2,21,23,25,27)(H2,24,26,29,30)/b15-8- NWOSWDZXQGJZLT-NVNXTCNLSA-N 219414 US9303033, K23, Table 37A, Compound 88 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219414 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219414&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335818 329994593 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383904 FC(F)(F)c1cccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C20H17F3N8O2/c21-20(22,23)12-3-1-2-10(6-12)8-24-17-28-15-11(7-14-16(32)29-19(33)27-14)9-25-31(15)18(30-17)26-13-4-5-13/h1-3,6-7,9,13H,4-5,8H2,(H2,24,26,28,30)(H2,27,29,32,33)/b14-7- NJLOPGYWYZAXIE-AUWJEWJLSA-N 219415 US9303033, L23, Table 37A, Compound 89 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219415 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219415&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335613 329994594 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383905 COc1ccccc1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H20N8O3/c1-31-15-5-3-2-4-11(15)9-21-18-25-16-12(8-14-17(29)26-20(30)24-14)10-22-28(16)19(27-18)23-13-6-7-13/h2-5,8,10,13H,6-7,9H2,1H3,(H2,21,23,25,27)(H2,24,26,29,30)/b14-8- YROJTZZWJIFFQA-ZSOIEALJSA-N 219416 US9303033, M23, Table 37A, Compound 90 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219416 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219416&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89888209 329994595 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383906 CC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1cccs1 InChI=1S/C18H18N8O2S/c1-9(13-3-2-6-29-13)20-16-23-14-10(7-12-15(27)24-18(28)22-12)8-19-26(14)17(25-16)21-11-4-5-11/h2-3,6-9,11H,4-5H2,1H3,(H2,20,21,23,25)(H2,22,24,27,28)/b12-7- OOVSMCOQSSYNQR-GHXNOFRVSA-N 219417 US9303033, N23, Table 37A, Compound 91 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219417 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219417&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335358 329994596 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383907 CC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccn1 InChI=1S/C19H19N9O2/c1-10(13-4-2-3-7-20-13)22-17-25-15-11(8-14-16(29)26-19(30)24-14)9-21-28(15)18(27-17)23-12-5-6-12/h2-4,7-10,12H,5-6H2,1H3,(H2,22,23,25,27)(H2,24,26,29,30)/b14-8- UATGVDJLQLGXHO-ZSOIEALJSA-N 219418 US9303033, O23, Table 37A, Compound 92 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219418 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219418&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67254199 329994597 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383908 Fc1cc(F)cc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C19H16F2N8O2/c20-11-3-9(4-12(21)6-11)7-22-17-26-15-10(5-14-16(30)27-19(31)25-14)8-23-29(15)18(28-17)24-13-1-2-13/h3-6,8,13H,1-2,7H2,(H2,22,24,26,28)(H2,25,27,30,31)/b14-5- UAZPHLBSYFRIQY-RZNTYIFUSA-N 219419 US9303033, P23, Table 37A, Compound 93 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219419 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219419&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335820 329994598 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383909 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NC3CCc4ccccc34)nc12 InChI=1S/C21H20N8O2/c30-18-16(25-21(31)27-18)9-12-10-22-29-17(12)26-19(28-20(29)23-13-6-7-13)24-15-8-5-11-3-1-2-4-14(11)15/h1-4,9-10,13,15H,5-8H2,(H2,23,24,26,28)(H2,25,27,30,31)/b16-9- OXDPWRLJMBDTDO-SXGWCWSVSA-N 219420 US9303033, Q23, Table 37A, Compound 94 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219420 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219420&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335622 329994599 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383910 CC(C)(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1 InChI=1S/C21H22N8O2/c1-21(2,13-6-4-3-5-7-13)28-18-25-16-12(10-15-17(30)26-20(31)24-15)11-22-29(16)19(27-18)23-14-8-9-14/h3-7,10-11,14H,8-9H2,1-2H3,(H2,23,25,27,28)(H2,24,26,30,31)/b15-10- QQKVOBGEFLRZRS-GDNBJRDFSA-N 219421 US9303033, R23, Table 37A, Compound 95 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219421 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219421&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89888221 329994600 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383911 C[C@@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccc(F)cc1 InChI=1S/C20H19FN8O2/c1-10(11-2-4-13(21)5-3-11)23-18-26-16-12(8-15-17(30)27-20(31)25-15)9-22-29(16)19(28-18)24-14-6-7-14/h2-5,8-10,14H,6-7H2,1H3,(H2,23,24,26,28)(H2,25,27,30,31)/b15-8-/t10-/m1/s1 ZKZDKVXNWCZCEZ-IIBSKXHVSA-N 219422 US9303033, S23, Table 37A, Compound 96 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219422&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336120 329994601 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383912 CC[C@@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1 InChI=1S/C21H22N8O2/c1-2-15(12-6-4-3-5-7-12)24-19-26-17-13(10-16-18(30)27-21(31)25-16)11-22-29(17)20(28-19)23-14-8-9-14/h3-7,10-11,14-15H,2,8-9H2,1H3,(H2,23,24,26,28)(H2,25,27,30,31)/b16-10-/t15-/m1/s1 ROALQCJTIUWAEH-CCAPLTMGSA-N 219423 US9303033, T23, Table 37A, Compound 97 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219423 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219423&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336122 329994602 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383913 C[C@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccc(F)cc1 InChI=1S/C20H19FN8O2/c1-10(11-2-4-13(21)5-3-11)23-18-26-16-12(8-15-17(30)27-20(31)25-15)9-22-29(16)19(28-18)24-14-6-7-14/h2-5,8-10,14H,6-7H2,1H3,(H2,23,24,26,28)(H2,25,27,30,31)/b15-8-/t10-/m0/s1 ZKZDKVXNWCZCEZ-SOOGHKCXSA-N 219424 US9303033, U23, Table 37A, Compound 98 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219424 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219424&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335200 329994603 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383914 Cn1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)n1 InChI=1S/C17H18N10O2/c1-26-5-4-11(25-26)8-18-15-22-13-9(6-12-14(28)23-17(29)21-12)7-19-27(13)16(24-15)20-10-2-3-10/h4-7,10H,2-3,8H2,1H3,(H2,18,20,22,24)(H2,21,23,28,29)/b12-6- UKFPNZFTOQDSEW-SDQBBNPISA-N 219425 US9303033, V23, Table 37A, Compound 99 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219425 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219425&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336121 329994604 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383915 Fc1ccccc1Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H15FN8O2/c19-11-3-1-2-4-12(11)22-16-24-14-9(7-13-15(28)25-18(29)23-13)8-20-27(14)17(26-16)21-10-5-6-10/h1-4,7-8,10H,5-6H2,(H2,21,22,24,26)(H2,23,25,28,29)/b13-7- OFCBLXDQWFETEA-QPEQYQDCSA-N 219426 US9303033, W23, Table 37A, Compound 100 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219426 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219426&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335823 329994605 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383916 COc1cccc(Nc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1Cl InChI=1S/C19H17ClN8O3/c1-31-13-4-2-3-11(14(13)20)23-17-25-15-9(7-12-16(29)26-19(30)24-12)8-21-28(15)18(27-17)22-10-5-6-10/h2-4,7-8,10H,5-6H2,1H3,(H2,22,23,25,27)(H2,24,26,29,30)/b12-7- BPMAHSXKUGOHJN-GHXNOFRVSA-N 219427 US9303033, X23, Table 37A, Compound 101 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219427 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219427&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 121257425 329994606 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383917 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NC(C3CC3)C3CC3)nc12 InChI=1S/C19H22N8O2/c28-16-13(22-19(29)25-16)7-11-8-20-27-15(11)24-17(26-18(27)21-12-5-6-12)23-14(9-1-2-9)10-3-4-10/h7-10,12,14H,1-6H2,(H2,21,23,24,26)(H2,22,25,28,29)/b13-7- ICYSUPBDXLBPDB-QPEQYQDCSA-N 219428 US9303033, Y23, Table 37A, Compound 102 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219428 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219428&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336010 329994607 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383918 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(N[C@H]3CC[C@@H](CC3)C#N)nc12 InChI=1S/C19H21N9O2/c20-8-10-1-3-12(4-2-10)22-17-25-15-11(7-14-16(29)26-19(30)24-14)9-21-28(15)18(27-17)23-13-5-6-13/h7,9-10,12-13H,1-6H2,(H2,22,23,25,27)(H2,24,26,29,30)/b14-7-/t10-,12- LDZRHCQTYDIQQJ-OOPDSENQSA-N 219429 US9303033, Z23, Table 37A, Compound 103 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219429 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219429&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335370 329994608 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383919 CN(C)C(=O)c1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C22H23N9O3/c1-30(2)19(33)13-5-3-12(4-6-13)10-23-20-27-17-14(9-16-18(32)28-22(34)26-16)11-24-31(17)21(29-20)25-15-7-8-15/h3-6,9,11,15H,7-8,10H2,1-2H3,(H2,23,25,27,29)(H2,26,28,32,34)/b16-9- PUFGPYLXAOFOKU-SXGWCWSVSA-N 219430 US9303033, A24, Table 37A, Compound 104 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219430 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219430&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335620 329994609 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383920 CNC(=O)c1cccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C21H21N9O3/c1-22-17(31)12-4-2-3-11(7-12)9-23-19-27-16-13(8-15-18(32)28-21(33)26-15)10-24-30(16)20(29-19)25-14-5-6-14/h2-4,7-8,10,14H,5-6,9H2,1H3,(H,22,31)(H2,23,25,27,29)(H2,26,28,32,33)/b15-8- KGXNXKBWMRPUOY-NVNXTCNLSA-N 219431 US9303033, B24, Table 37A, Compound 105 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219431 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219431&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335237 329994610 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383921 CC1(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)COC1 InChI=1S/C17H20N8O3/c1-17(7-28-8-17)6-18-14-22-12-9(4-11-13(26)23-16(27)21-11)5-19-25(12)15(24-14)20-10-2-3-10/h4-5,10H,2-3,6-8H2,1H3,(H2,18,20,22,24)(H2,21,23,26,27)/b11-4- MDRQQEXIVHHEJB-WCIBSUBMSA-N 219432 US9303033, C24, Table 37A, Compound 106 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219432 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219432&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336008 329994611 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383922 OCC1CCN(CC1)c1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C25H29N9O3/c35-14-16-7-9-33(10-8-16)19-5-1-15(2-6-19)12-26-23-30-21-17(11-20-22(36)31-25(37)29-20)13-27-34(21)24(32-23)28-18-3-4-18/h1-2,5-6,11,13,16,18,35H,3-4,7-10,12,14H2,(H2,26,28,30,32)(H2,29,31,36,37)/b20-11- UDIBYJYFPFCKBV-JAIQZWGSSA-N 219433 US9303033, D24, Table 37A, Compound 107 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219433&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335826 329994612 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383923 CC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccc(cc1)-n1ccnc1 InChI=1S/C23H22N10O2/c1-13(14-2-6-17(7-3-14)32-9-8-24-12-32)26-21-29-19-15(10-18-20(34)30-23(35)28-18)11-25-33(19)22(31-21)27-16-4-5-16/h2-3,6-13,16H,4-5H2,1H3,(H2,26,27,29,31)(H2,28,30,34,35)/b18-10- YEOHRZQCEKTFLK-ZDLGFXPLSA-N 219434 US9303033, E24, Table 37A, Compound 108 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219434 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219434&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335373 329994613 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383924 C[C@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccc(cc1)C(F)(F)F InChI=1S/C21H19F3N8O2/c1-10(11-2-4-13(5-3-11)21(22,23)24)26-18-29-16-12(8-15-17(33)30-20(34)28-15)9-25-32(16)19(31-18)27-14-6-7-14/h2-5,8-10,14H,6-7H2,1H3,(H2,26,27,29,31)(H2,28,30,33,34)/b15-8-/t10-/m0/s1 VWAAMJVETWDLFF-SOOGHKCXSA-N 219435 US9303033, F24, Table 37A, Compound 109 Casein kinase II subunit beta 313.9 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219435 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219435&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335372 329994614 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383925 CC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1cc(Cl)ccc1Cl InChI=1S/C20H18Cl2N8O2/c1-9(13-7-11(21)2-5-14(13)22)24-18-27-16-10(6-15-17(31)28-20(32)26-15)8-23-30(16)19(29-18)25-12-3-4-12/h2,5-9,12H,3-4H2,1H3,(H2,24,25,27,29)(H2,26,28,31,32)/b15-6- DUHUOMJKFJGWKG-UUASQNMZSA-N 219436 US9303033, G24, Table 37A, Compound 110 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219436 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219436&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336119 329994615 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383926 CC(C)C(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1cccs1 InChI=1S/C20H22N8O2S/c1-10(2)15(14-4-3-7-31-14)24-18-25-16-11(8-13-17(29)26-20(30)23-13)9-21-28(16)19(27-18)22-12-5-6-12/h3-4,7-10,12,15H,5-6H2,1-2H3,(H2,22,24,25,27)(H2,23,26,29,30)/b13-8- RCJHRLULOQIJGZ-JYRVWZFOSA-N 219437 US9303033, H24, Table 37A, Compound 111 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219437 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219437&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335369 329994616 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383927 CN1C(=O)C(Nc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c2ccccc12 InChI=1S/C21H19N9O3/c1-29-14-5-3-2-4-12(14)15(18(29)32)25-19-26-16-10(8-13-17(31)27-21(33)24-13)9-22-30(16)20(28-19)23-11-6-7-11/h2-5,8-9,11,15H,6-7H2,1H3,(H2,23,25,26,28)(H2,24,27,31,33)/b13-8- SUZYWGSEEIWQNM-JYRVWZFOSA-N 219438 US9303033, I24, Table 37A, Compound 112 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219438 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219438&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336013 329994617 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383928 CN(C)CCC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1 InChI=1S/C23H27N9O2/c1-31(2)11-10-17(14-6-4-3-5-7-14)26-21-28-19-15(12-18-20(33)29-23(34)27-18)13-24-32(19)22(30-21)25-16-8-9-16/h3-7,12-13,16-17H,8-11H2,1-2H3,(H2,25,26,28,30)(H2,27,29,33,34)/b18-12- URCWLBFYCKDVRB-PDGQHHTCSA-N 219439 US9303033, J24, Table 37A, Compound 113 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219439 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219439&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336127 329994618 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383929 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NC(Cn3ccnc3)c3ccccc3)nc12 InChI=1S/C23H22N10O2/c34-20-17(28-23(35)30-20)10-15-11-25-33-19(15)29-21(31-22(33)26-16-6-7-16)27-18(12-32-9-8-24-13-32)14-4-2-1-3-5-14/h1-5,8-11,13,16,18H,6-7,12H2,(H2,26,27,29,31)(H2,28,30,34,35)/b17-10- MTTVZXCUHSYRFT-YVLHZVERSA-N 219440 US9303033, K24, Table 37A, Compound 114 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219440 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219440&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336126 329994619 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383930 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NC(CN3CCCC3)c3ccccc3)nc12 InChI=1S/C24H27N9O2/c34-21-18(28-24(35)30-21)12-16-13-25-33-20(16)29-22(31-23(33)26-17-8-9-17)27-19(14-32-10-4-5-11-32)15-6-2-1-3-7-15/h1-3,6-7,12-13,17,19H,4-5,8-11,14H2,(H2,26,27,29,31)(H2,28,30,34,35)/b18-12- TVYWXEOPONLDIY-PDGQHHTCSA-N 219441 US9303033, L24, Table 37A, Compound 115 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219441 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219441&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336098 329994620 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383931 Cc1cccc(C)c1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H22N8O2/c1-11-4-3-5-12(2)15(11)10-22-19-26-17-13(8-16-18(30)27-21(31)25-16)9-23-29(17)20(28-19)24-14-6-7-14/h3-5,8-9,14H,6-7,10H2,1-2H3,(H2,22,24,26,28)(H2,25,27,30,31)/b16-8- GNBPGHFCDDKBGH-PXNMLYILSA-N 219442 US9303033, M24, Table 37A, Compound 116 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219442 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219442&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335602 329994621 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383932 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3cccc(c3)-n3cccn3)nc12 InChI=1S/C22H20N10O2/c33-19-17(27-22(34)29-19)10-14-12-25-32-18(14)28-20(30-21(32)26-15-5-6-15)23-11-13-3-1-4-16(9-13)31-8-2-7-24-31/h1-4,7-10,12,15H,5-6,11H2,(H2,23,26,28,30)(H2,27,29,33,34)/b17-10- GMHZZGRQQLRFDK-YVLHZVERSA-N 219443 US9303033, N24, Table 37A, Compound 117 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219443 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219443&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336123 329994622 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383933 FC(F)(F)c1cc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)ccc1Cl InChI=1S/C20H16ClF3N8O2/c21-13-4-1-9(5-12(13)20(22,23)24)7-25-17-29-15-10(6-14-16(33)30-19(34)28-14)8-26-32(15)18(31-17)27-11-2-3-11/h1,4-6,8,11H,2-3,7H2,(H2,25,27,29,31)(H2,28,30,33,34)/b14-6- DVEOCZUNQRYUQX-NSIKDUERSA-N 219444 US9303033, O24, Table 37A, Compound 118 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219444 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219444&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335810 329994623 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383934 Fc1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1C(F)(F)F InChI=1S/C20H16F4N8O2/c21-13-4-1-9(5-12(13)20(22,23)24)7-25-17-29-15-10(6-14-16(33)30-19(34)28-14)8-26-32(15)18(31-17)27-11-2-3-11/h1,4-6,8,11H,2-3,7H2,(H2,25,27,29,31)(H2,28,30,33,34)/b14-6- AMDMACCAWNPZCM-NSIKDUERSA-N 219445 US9303033, P24, Table 37A, Compound 119 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219445&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335619 329994624 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383935 CCN1CCN(Cc2ccc(CNc3nc(NC4CC4)n4ncc(\C=C5/NC(=O)NC5=O)c4n3)cc2)CC1 InChI=1S/C26H32N10O2/c1-2-34-9-11-35(12-10-34)16-18-5-3-17(4-6-18)14-27-24-31-22-19(13-21-23(37)32-26(38)30-21)15-28-36(22)25(33-24)29-20-7-8-20/h3-6,13,15,20H,2,7-12,14,16H2,1H3,(H2,27,29,31,33)(H2,30,32,37,38)/b21-13- WMVYBZPOPQOFJV-BKUYFWCQSA-N 219446 US9303033, Q24, Table 37A, Compound 120 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219446 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219446&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335827 329994625 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383936 O[C@H]1CCN(C1)C(=O)[C@@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1 InChI=1S/C24H25N9O4/c34-16-8-9-32(12-16)21(36)18(13-4-2-1-3-5-13)28-22-29-19-14(10-17-20(35)30-24(37)27-17)11-25-33(19)23(31-22)26-15-6-7-15/h1-5,10-11,15-16,18,34H,6-9,12H2,(H2,26,28,29,31)(H2,27,30,35,37)/b17-10-/t16-,18-/m0/s1 LUXDVYWBLACUHO-ZTTDCBHNSA-N 219447 US9303033, R24, Table 37A, Compound 121 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219447 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219447&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335615 329994626 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383937 CC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccc2OCCOc2c1 InChI=1S/C22H22N8O4/c1-11(12-2-5-16-17(9-12)34-7-6-33-16)24-20-27-18-13(8-15-19(31)28-22(32)26-15)10-23-30(18)21(29-20)25-14-3-4-14/h2,5,8-11,14H,3-4,6-7H2,1H3,(H2,24,25,27,29)(H2,26,28,31,32)/b15-8- ATKZDVUKAXNYFI-NVNXTCNLSA-N 219448 US9303033, S24, Table 37A, Compound 122 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219448&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335623 329994627 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383938 CC(C)c1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C22H24N8O2/c1-12(2)14-5-3-13(4-6-14)10-23-20-27-18-15(9-17-19(31)28-22(32)26-17)11-24-30(18)21(29-20)25-16-7-8-16/h3-6,9,11-12,16H,7-8,10H2,1-2H3,(H2,23,25,27,29)(H2,26,28,31,32)/b17-9- UJLPUWJKHICNDU-MFOYZWKCSA-N 219449 US9303033, T24, Table 37A, Compound 123 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219449 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219449&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89887974 329994628 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383939 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NC3CCOc4ccccc34)nc12 InChI=1S/C21H20N8O3/c30-18-15(25-21(31)27-18)9-11-10-22-29-17(11)26-19(28-20(29)23-12-5-6-12)24-14-7-8-32-16-4-2-1-3-13(14)16/h1-4,9-10,12,14H,5-8H2,(H2,23,24,26,28)(H2,25,27,30,31)/b15-9- TWHMQMWMVNXCAS-DHDCSXOGSA-N 219450 US9303033, U24, Table 37A, Compound 124 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219450 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219450&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335630 329994629 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383940 C[C@@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1cc(cc(c1)C(F)(F)F)C(F)(F)F InChI=1S/C22H18F6N8O2/c1-9(10-4-12(21(23,24)25)7-13(5-10)22(26,27)28)30-18-33-16-11(6-15-17(37)34-20(38)32-15)8-29-36(16)19(35-18)31-14-2-3-14/h4-9,14H,2-3H2,1H3,(H2,30,31,33,35)(H2,32,34,37,38)/b15-6-/t9-/m1/s1 PJPBEZYRAJAXKL-PHKJPBFMSA-N 219451 US9303033, V24, Table 37A, Compound 125 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219451 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219451&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 88941214 329994630 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383941 CCc1ccc(cc1)C(C)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H24N8O2/c1-3-13-4-6-14(7-5-13)12(2)24-20-27-18-15(10-17-19(31)28-22(32)26-17)11-23-30(18)21(29-20)25-16-8-9-16/h4-7,10-12,16H,3,8-9H2,1-2H3,(H2,24,25,27,29)(H2,26,28,31,32)/b17-10- GAYBMVUZJOZTSO-YVLHZVERSA-N 219452 US9303033, W24, Table 37A, Compound 126 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219452 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219452&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335376 329994631 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383942 CCC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccc(C)cc1 InChI=1S/C22H24N8O2/c1-3-16(13-6-4-12(2)5-7-13)25-20-27-18-14(10-17-19(31)28-22(32)26-17)11-23-30(18)21(29-20)24-15-8-9-15/h4-7,10-11,15-16H,3,8-9H2,1-2H3,(H2,24,25,27,29)(H2,26,28,31,32)/b17-10- YCYPPJYDOFSEEI-YVLHZVERSA-N 219453 US9303033, X24, Table 37A, Compound 127 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219453&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89888210 329994632 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383943 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3ccc(cc3)-c3csnn3)nc12 InChI=1S/C21H18N10O2S/c32-18-15(25-21(33)27-18)7-13-9-23-31-17(13)26-19(28-20(31)24-14-5-6-14)22-8-11-1-3-12(4-2-11)16-10-34-30-29-16/h1-4,7,9-10,14H,5-6,8H2,(H2,22,24,26,28)(H2,25,27,32,33)/b15-7- IISHOHLMOMQCNU-CHHVJCJISA-N 219454 US9303033, Y24, Table 37A, Compound 128 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219454 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219454&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335626 329994633 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383944 Cc1ccsc1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H18N8O2S/c1-9-4-5-29-13(9)8-19-16-23-14-10(6-12-15(27)24-18(28)22-12)7-20-26(14)17(25-16)21-11-2-3-11/h4-7,11H,2-3,8H2,1H3,(H2,19,21,23,25)(H2,22,24,27,28)/b12-6- QNFQUBVOEPIUJN-SDQBBNPISA-N 219455 US9303033, Z24, Table 37A, Compound 129 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219455 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219455&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314560 329994634 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383945 C[C@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccc(C)cc1 InChI=1S/C21H22N8O2/c1-11-3-5-13(6-4-11)12(2)23-19-26-17-14(9-16-18(30)27-21(31)25-16)10-22-29(17)20(28-19)24-15-7-8-15/h3-6,9-10,12,15H,7-8H2,1-2H3,(H2,23,24,26,28)(H2,25,27,30,31)/b16-9-/t12-/m0/s1 LJPJQDNRSMCNMI-PFSWGADMSA-N 219456 US9303033, A25, Table 37A, Compound 130 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219456&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336129 329994635 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383946 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3ccc(CN4CCCC4)cc3)nc12 InChI=1S/C24H27N9O2/c34-21-19(28-24(35)30-21)11-17-13-26-33-20(17)29-22(31-23(33)27-18-7-8-18)25-12-15-3-5-16(6-4-15)14-32-9-1-2-10-32/h3-6,11,13,18H,1-2,7-10,12,14H2,(H2,25,27,29,31)(H2,28,30,34,35)/b19-11- SUDIXYVYMWWNCL-ODLFYWEKSA-N 219457 US9303033, B25, Table 37A, Compound 131 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219457 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219457&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335819 329994636 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383947 C[C@@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1C(F)(F)F InChI=1S/C21H19F3N8O2/c1-10(13-4-2-3-5-14(13)21(22,23)24)26-18-29-16-11(8-15-17(33)30-20(34)28-15)9-25-32(16)19(31-18)27-12-6-7-12/h2-5,8-10,12H,6-7H2,1H3,(H2,26,27,29,31)(H2,28,30,33,34)/b15-8-/t10-/m1/s1 LWDVTAHGIVOOGG-IIBSKXHVSA-N 219458 US9303033, C25, Table 37A, Compound 132 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219458&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335832 329994637 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383948 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3ccccc3N3CCCCC3)nc12 InChI=1S/C24H27N9O2/c34-21-18(28-24(35)30-21)12-16-14-26-33-20(16)29-22(31-23(33)27-17-8-9-17)25-13-15-6-2-3-7-19(15)32-10-4-1-5-11-32/h2-3,6-7,12,14,17H,1,4-5,8-11,13H2,(H2,25,27,29,31)(H2,28,30,34,35)/b18-12- AGUBCKFLTPAHDD-PDGQHHTCSA-N 219459 US9303033, D25, Table 37A, Compound 133 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219459&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313741 329994638 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383949 O[C@H]1Cc2ccccc2[C@@H]1Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H20N8O3/c30-15-8-10-3-1-2-4-13(10)16(15)25-19-26-17-11(7-14-18(31)27-21(32)24-14)9-22-29(17)20(28-19)23-12-5-6-12/h1-4,7,9,12,15-16,30H,5-6,8H2,(H2,23,25,26,28)(H2,24,27,31,32)/b14-7-/t15-,16-/m0/s1 IFVKGXXFFHIRNY-BKZJWICZSA-N 219460 US9303033, E25, Table 37A, Compound 134 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219460&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335625 329994639 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383950 OC(=O)c1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C20H18N8O4/c29-16-14(24-20(32)26-16)7-12-9-22-28-15(12)25-18(27-19(28)23-13-5-6-13)21-8-10-1-3-11(4-2-10)17(30)31/h1-4,7,9,13H,5-6,8H2,(H,30,31)(H2,21,23,25,27)(H2,24,26,29,32)/b14-7- SWGHVCQXVOPXBC-AUWJEWJLSA-N 219461 US9303033, F25, Table 37A, Compound 135 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219461 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219461&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336132 329994640 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383951 Fc1cc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc(c1)C(F)(F)F InChI=1S/C20H16F4N8O2/c21-12-4-9(3-11(6-12)20(22,23)24)7-25-17-29-15-10(5-14-16(33)30-19(34)28-14)8-26-32(15)18(31-17)27-13-1-2-13/h3-6,8,13H,1-2,7H2,(H2,25,27,29,31)(H2,28,30,33,34)/b14-5- SPQWULKFWXXIAW-RZNTYIFUSA-N 219462 US9303033, G25, Table 37A, Compound 136 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219462&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314461 329994641 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383952 Fc1ccc(c(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1)C(F)(F)F InChI=1S/C20H16F4N8O2/c21-11-1-4-13(20(22,23)24)9(5-11)7-25-17-29-15-10(6-14-16(33)30-19(34)28-14)8-26-32(15)18(31-17)27-12-2-3-12/h1,4-6,8,12H,2-3,7H2,(H2,25,27,29,31)(H2,28,30,33,34)/b14-6- SRKHPCLLBVRYCP-NSIKDUERSA-N 219463 US9303033, H25, Table 37A, Compound 137 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219463 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219463&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335374 329994642 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383953 C[C@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccc(Cl)cc1 InChI=1S/C20H19ClN8O2/c1-10(11-2-4-13(21)5-3-11)23-18-26-16-12(8-15-17(30)27-20(31)25-15)9-22-29(16)19(28-18)24-14-6-7-14/h2-5,8-10,14H,6-7H2,1H3,(H2,23,24,26,28)(H2,25,27,30,31)/b15-8-/t10-/m0/s1 XBLZKWARYFXIKW-SOOGHKCXSA-N 219464 US9303033, I25, Table 37A, Compound 138 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219464 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219464&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335192 329994643 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383954 CN(C(C)=O)c1cccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C22H23N9O3/c1-12(32)30(2)16-5-3-4-13(8-16)10-23-20-27-18-14(9-17-19(33)28-22(34)26-17)11-24-31(18)21(29-20)25-15-6-7-15/h3-5,8-9,11,15H,6-7,10H2,1-2H3,(H2,23,25,27,29)(H2,26,28,33,34)/b17-9- GZPXAPTVUILKBD-MFOYZWKCSA-N 219465 US9303033, J25, Table 37A, Compound 139 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219465&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89888212 329994644 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383955 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3ccc(cc3)N3CCCC3=O)nc12 InChI=1S/C23H23N9O3/c33-18-2-1-9-31(18)16-7-3-13(4-8-16)11-24-21-28-19-14(10-17-20(34)29-23(35)27-17)12-25-32(19)22(30-21)26-15-5-6-15/h3-4,7-8,10,12,15H,1-2,5-6,9,11H2,(H2,24,26,28,30)(H2,27,29,34,35)/b17-10- ZNWFEJVVKDIPLA-YVLHZVERSA-N 219466 US9303033, K25, Table 37A, Compound 140 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219466 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219466&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335628 329994645 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383956 CC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1cccc(c1)C(F)(F)F InChI=1S/C21H19F3N8O2/c1-10(11-3-2-4-13(7-11)21(22,23)24)26-18-29-16-12(8-15-17(33)30-20(34)28-15)9-25-32(16)19(31-18)27-14-5-6-14/h2-4,7-10,14H,5-6H2,1H3,(H2,26,27,29,31)(H2,28,30,33,34)/b15-8- IOEDDKHKJJGPAR-NVNXTCNLSA-N 219467 US9303033, L25, Table 37A, Compound 141 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219467&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313841 329994646 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383957 FC(F)(F)c1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cn1 InChI=1S/C19H16F3N9O2/c20-19(21,22)13-4-1-9(6-23-13)7-24-16-28-14-10(5-12-15(32)29-18(33)27-12)8-25-31(14)17(30-16)26-11-2-3-11/h1,4-6,8,11H,2-3,7H2,(H2,24,26,28,30)(H2,27,29,32,33)/b12-5- WDUAOIWWAIWTDM-XGICHPGQSA-N 219468 US9303033, M25, Table 37A, Compound 142 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219468&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335367 329994647 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383958 CCC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccc2OCCOc2c1 InChI=1S/C23H24N8O4/c1-2-15(12-3-6-17-18(10-12)35-8-7-34-17)26-21-28-19-13(9-16-20(32)29-23(33)27-16)11-24-31(19)22(30-21)25-14-4-5-14/h3,6,9-11,14-15H,2,4-5,7-8H2,1H3,(H2,25,26,28,30)(H2,27,29,32,33)/b16-9- WCDQIBFAYOHRGI-SXGWCWSVSA-N 219469 US9303033, N25, Table 37A, Compound 143 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219469 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219469&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314465 329994648 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383959 CN(C)CC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1 InChI=1S/C22H25N9O2/c1-30(2)12-17(13-6-4-3-5-7-13)25-20-27-18-14(10-16-19(32)28-22(33)26-16)11-23-31(18)21(29-20)24-15-8-9-15/h3-7,10-11,15,17H,8-9,12H2,1-2H3,(H2,24,25,27,29)(H2,26,28,32,33)/b16-10- APCOCRQLBIEWFU-YBEGLDIGSA-N 219470 US9303033, O25, Table 37A, Compound 144 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219470&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335188 329994649 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383960 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3nc4CCCCCc4s3)nc12 InChI=1S/C21H23N9O2S/c31-18-14(26-21(32)28-18)8-11-9-23-30-17(11)27-19(29-20(30)24-12-6-7-12)22-10-16-25-13-4-2-1-3-5-15(13)33-16/h8-9,12H,1-7,10H2,(H2,22,24,27,29)(H2,26,28,31,32)/b14-8- MDPDMLQEIIFQRV-ZSOIEALJSA-N 219471 US9303033, P25, Table 37A, Compound 145 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219471&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336018 329994650 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383961 CC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccc(cc1)S(C)(=O)=O InChI=1S/C21H22N8O4S/c1-11(12-3-7-15(8-4-12)34(2,32)33)23-19-26-17-13(9-16-18(30)27-21(31)25-16)10-22-29(17)20(28-19)24-14-5-6-14/h3-4,7-11,14H,5-6H2,1-2H3,(H2,23,24,26,28)(H2,25,27,30,31)/b16-9- GOGWLFHMFFPYDU-SXGWCWSVSA-N 219472 US9303033, Q25, Table 37A, Compound 146 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219472&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336020 329994651 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383962 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3ccc(cc3)-n3cccn3)nc12 InChI=1S/C22H20N10O2/c33-19-17(27-22(34)29-19)10-14-12-25-32-18(14)28-20(30-21(32)26-15-4-5-15)23-11-13-2-6-16(7-3-13)31-9-1-8-24-31/h1-3,6-10,12,15H,4-5,11H2,(H2,23,26,28,30)(H2,27,29,33,34)/b17-10- RCIVVVLRQHMQMG-YVLHZVERSA-N 219473 US9303033, R25, Table 37A, Compound 147 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219473&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335837 329994652 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383963 CC(C)(C)OC(=O)N1CCC(CC1)c1ncccc1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C28H34N10O4/c1-28(2,3)42-27(41)37-11-8-16(9-12-37)21-17(5-4-10-29-21)14-30-24-34-22-18(13-20-23(39)35-26(40)33-20)15-31-38(22)25(36-24)32-19-6-7-19/h4-5,10,13,15-16,19H,6-9,11-12,14H2,1-3H3,(H2,30,32,34,36)(H2,33,35,39,40)/b20-13- QHRYVJWFEFZJIF-MOSHPQCFSA-N 219474 US9303033, S25, Table 37A, Compound 148 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219474&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89888211 329994653 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383964 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3cccc4OCCCOc34)nc12 InChI=1S/C22H22N8O4/c31-19-15(26-22(32)28-19)9-13-11-24-30-18(13)27-20(29-21(30)25-14-5-6-14)23-10-12-3-1-4-16-17(12)34-8-2-7-33-16/h1,3-4,9,11,14H,2,5-8,10H2,(H2,23,25,27,29)(H2,26,28,31,32)/b15-9- VNKNGTFSCHPIQK-DHDCSXOGSA-N 219475 US9303033, T25, Table 37A, Compound 149 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219475 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219475&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335382 329994654 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383965 OC(=O)c1cccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C20H18N8O4/c29-16-14(24-20(32)26-16)7-12-9-22-28-15(12)25-18(27-19(28)23-13-4-5-13)21-8-10-2-1-3-11(6-10)17(30)31/h1-3,6-7,9,13H,4-5,8H2,(H,30,31)(H2,21,23,25,27)(H2,24,26,29,32)/b14-7- CRKAPKJNMRDHQQ-AUWJEWJLSA-N 219476 US9303033, U25, Table 37A, Compound 150 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219476 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219476&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335386 329994655 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383966 O=C(N1CCOCC1)c1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C24H25N9O4/c34-20-18(28-24(36)30-20)11-16-13-26-33-19(16)29-22(31-23(33)27-17-5-6-17)25-12-14-1-3-15(4-2-14)21(35)32-7-9-37-10-8-32/h1-4,11,13,17H,5-10,12H2,(H2,25,27,29,31)(H2,28,30,34,36)/b18-11- CBMFDKOKCBRCJR-WQRHYEAKSA-N 219477 US9303033, V25, Table 37A, Compound 151 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219477 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219477&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335629 329994656 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383967 Oc1ccccc1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H18N8O3/c28-14-4-2-1-3-10(14)8-20-17-24-15-11(7-13-16(29)25-19(30)23-13)9-21-27(15)18(26-17)22-12-5-6-12/h1-4,7,9,12,28H,5-6,8H2,(H2,20,22,24,26)(H2,23,25,29,30)/b13-7- PEVPUNZMUJKSJJ-QPEQYQDCSA-N 219478 US9303033, W25, Table 37A, Compound 152 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219478 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219478&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335371 329994657 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383968 OC(=O)CC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1 InChI=1S/C21H20N8O4/c30-16(31)9-14(11-4-2-1-3-5-11)24-19-26-17-12(8-15-18(32)27-21(33)25-15)10-22-29(17)20(28-19)23-13-6-7-13/h1-5,8,10,13-14H,6-7,9H2,(H,30,31)(H2,23,24,26,28)(H2,25,27,32,33)/b15-8- MVMGVCIEQHRGIP-NVNXTCNLSA-N 219479 US9303033, X25, Table 37A, Compound 153 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219479&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335632 329994658 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383969 CC1CCN(Cc2ccc(CNc3nc(NC4CC4)n4ncc(\C=C5/NC(=O)NC5=O)c4n3)cc2)CC1 InChI=1S/C26H31N9O2/c1-16-8-10-34(11-9-16)15-18-4-2-17(3-5-18)13-27-24-31-22-19(12-21-23(36)32-26(37)30-21)14-28-35(22)25(33-24)29-20-6-7-20/h2-5,12,14,16,20H,6-11,13,15H2,1H3,(H2,27,29,31,33)(H2,30,32,36,37)/b21-12- PCUFQVPQRBXMMZ-MTJSOVHGSA-N 219480 US9303033, Y25, Table 37A, Compound 154 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219480&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89888236 329994659 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383970 CC(C)Oc1ccccc1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H24N8O3/c1-12(2)33-17-6-4-3-5-13(17)10-23-20-27-18-14(9-16-19(31)28-22(32)26-16)11-24-30(18)21(29-20)25-15-7-8-15/h3-6,9,11-12,15H,7-8,10H2,1-2H3,(H2,23,25,27,29)(H2,26,28,31,32)/b16-9- OZJFLDXDYVJEMG-SXGWCWSVSA-N 219481 US9303033, Z25, Table 37A, Compound 155 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219481 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219481&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335388 329994660 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383971 Cc1cc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)nn1C InChI=1S/C18H20N10O2/c1-9-5-12(26-27(9)2)8-19-16-23-14-10(6-13-15(29)24-18(30)22-13)7-20-28(14)17(25-16)21-11-3-4-11/h5-7,11H,3-4,8H2,1-2H3,(H2,19,21,23,25)(H2,22,24,29,30)/b13-6- RVCZHAVBRQSTPQ-MLPAPPSSSA-N 219482 US9303033, A26, Table 37A, Compound 156 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219482 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219482&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336016 329994661 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383972 CCc1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C21H22N8O2/c1-2-12-3-5-13(6-4-12)10-22-19-26-17-14(9-16-18(30)27-21(31)25-16)11-23-29(17)20(28-19)24-15-7-8-15/h3-6,9,11,15H,2,7-8,10H2,1H3,(H2,22,24,26,28)(H2,25,27,30,31)/b16-9- OSLYSCPHEHAFGH-SXGWCWSVSA-N 219483 US9303033, B26, Table 37A, Compound 157 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219483&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89887977 329994662 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383973 CN(C)Cc1cccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C22H25N9O2/c1-30(2)12-14-5-3-4-13(8-14)10-23-20-27-18-15(9-17-19(32)28-22(33)26-17)11-24-31(18)21(29-20)25-16-6-7-16/h3-5,8-9,11,16H,6-7,10,12H2,1-2H3,(H2,23,25,27,29)(H2,26,28,32,33)/b17-9- CXBVQCUISMTCKO-MFOYZWKCSA-N 219484 US9303033, C26, Table 37A, Compound 158 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219484&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89888217 329994663 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383974 CSc1cccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C20H20N8O2S/c1-31-14-4-2-3-11(7-14)9-21-18-25-16-12(8-15-17(29)26-20(30)24-15)10-22-28(16)19(27-18)23-13-5-6-13/h2-4,7-8,10,13H,5-6,9H2,1H3,(H2,21,23,25,27)(H2,24,26,29,30)/b15-8- AGHHWRIONRDRFU-NVNXTCNLSA-N 219485 US9303033, D26, Table 37A, Compound 159 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219485 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219485&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315056 329994664 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383975 Cc1cc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c(C)o1 InChI=1S/C19H20N8O3/c1-9-5-11(10(2)30-9)7-20-17-24-15-12(6-14-16(28)25-19(29)23-14)8-21-27(15)18(26-17)22-13-3-4-13/h5-6,8,13H,3-4,7H2,1-2H3,(H2,20,22,24,26)(H2,23,25,28,29)/b14-6- PKSISZCZHWUASX-NSIKDUERSA-N 219486 US9303033, E26, Table 37A, Compound 160 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219486 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219486&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315009 329994665 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383976 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(N[C@H]3CCCc4ccccc34)nc12 InChI=1S/C22H22N8O2/c31-19-17(26-22(32)28-19)10-13-11-23-30-18(13)27-20(29-21(30)24-14-8-9-14)25-16-7-3-5-12-4-1-2-6-15(12)16/h1-2,4,6,10-11,14,16H,3,5,7-9H2,(H2,24,25,27,29)(H2,26,28,31,32)/b17-10-/t16-/m0/s1 VIHPHOJREHWUNF-IUPCOXQMSA-N 219487 US9303033, F26, Table 37A, Compound 161 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219487 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219487&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336031 329994666 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383977 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(N[C@@H]3CCCc4ccccc34)nc12 InChI=1S/C22H22N8O2/c31-19-17(26-22(32)28-19)10-13-11-23-30-18(13)27-20(29-21(30)24-14-8-9-14)25-16-7-3-5-12-4-1-2-6-15(12)16/h1-2,4,6,10-11,14,16H,3,5,7-9H2,(H2,24,25,27,29)(H2,26,28,31,32)/b17-10-/t16-/m1/s1 VIHPHOJREHWUNF-FNTDYBJHSA-N 219488 US9303033, G26, Table 37A, Compound 162 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219488 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219488&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335181 329994667 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383978 Fc1cc(Cl)ccc1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H16ClFN8O2/c20-11-2-1-9(13(21)6-11)7-22-17-26-15-10(5-14-16(30)27-19(31)25-14)8-23-29(15)18(28-17)24-12-3-4-12/h1-2,5-6,8,12H,3-4,7H2,(H2,22,24,26,28)(H2,25,27,30,31)/b14-5- BRPDSRPUCNKHFR-RZNTYIFUSA-N 219489 US9303033, H26, Table 37A, Compound 163 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219489 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219489&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335392 329994668 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383979 Fc1cc(ccc1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C(F)(F)F InChI=1S/C20H16F4N8O2/c21-13-6-11(20(22,23)24)2-1-9(13)7-25-17-29-15-10(5-14-16(33)30-19(34)28-14)8-26-32(15)18(31-17)27-12-3-4-12/h1-2,5-6,8,12H,3-4,7H2,(H2,25,27,29,31)(H2,28,30,33,34)/b14-5- DQBVYQPKFHIMCJ-RZNTYIFUSA-N 219490 US9303033, I26, Table 37A, Compound 164 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219490 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219490&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314174 329994669 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383980 OCC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1cc(Cl)cc(Cl)c1 InChI=1S/C20H18Cl2N8O3/c21-11-3-9(4-12(22)6-11)15(8-31)25-18-27-16-10(5-14-17(32)28-20(33)26-14)7-23-30(16)19(29-18)24-13-1-2-13/h3-7,13,15,31H,1-2,8H2,(H2,24,25,27,29)(H2,26,28,32,33)/b14-5- YVNAJAXXKMHKEX-RZNTYIFUSA-N 219491 US9303033, J26, Table 37A, Compound 165 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219491 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219491&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335387 329994670 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383981 C[C@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1cccc2ccccc12 InChI=1S/C24H22N8O2/c1-13(17-8-4-6-14-5-2-3-7-18(14)17)26-22-29-20-15(11-19-21(33)30-24(34)28-19)12-25-32(20)23(31-22)27-16-9-10-16/h2-8,11-13,16H,9-10H2,1H3,(H2,26,27,29,31)(H2,28,30,33,34)/b19-11-/t13-/m0/s1 KUSMLLAJLSJLKF-JFENUBAZSA-N 219492 US9303033, K26, Table 37A, Compound 166 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219492 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219492&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336128 329994671 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383982 CCOc1ccccc1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H22N8O3/c1-2-32-16-6-4-3-5-12(16)10-22-19-26-17-13(9-15-18(30)27-21(31)25-15)11-23-29(17)20(28-19)24-14-7-8-14/h3-6,9,11,14H,2,7-8,10H2,1H3,(H2,22,24,26,28)(H2,25,27,30,31)/b15-9- HLYRZZTUWILPKU-DHDCSXOGSA-N 219493 US9303033, L26, Table 37A, Compound 167 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219493&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336130 329994672 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383983 Cc1cc(Cl)ccc1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H19ClN8O2/c1-10-6-13(21)3-2-11(10)8-22-18-26-16-12(7-15-17(30)27-20(31)25-15)9-23-29(16)19(28-18)24-14-4-5-14/h2-3,6-7,9,14H,4-5,8H2,1H3,(H2,22,24,26,28)(H2,25,27,30,31)/b15-7- VZUSGKJSJQJBHM-CHHVJCJISA-N 219494 US9303033, M26, Table 37A, Compound 168 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219494 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219494&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89888223 329994673 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383984 CC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccc(F)c(F)c1 InChI=1S/C20H18F2N8O2/c1-9(10-2-5-13(21)14(22)6-10)24-18-27-16-11(7-15-17(31)28-20(32)26-15)8-23-30(16)19(29-18)25-12-3-4-12/h2,5-9,12H,3-4H2,1H3,(H2,24,25,27,29)(H2,26,28,31,32)/b15-7- NGIWXHCDWOYZCL-CHHVJCJISA-N 219495 US9303033, N26, Table 37A, Compound 169 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219495&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313981 329994674 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383985 Cc1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1Cl InChI=1S/C20H19ClN8O2/c1-10-2-3-11(6-14(10)21)8-22-18-26-16-12(7-15-17(30)27-20(31)25-15)9-23-29(16)19(28-18)24-13-4-5-13/h2-3,6-7,9,13H,4-5,8H2,1H3,(H2,22,24,26,28)(H2,25,27,30,31)/b15-7- RCRDMVSZYYDRPO-CHHVJCJISA-N 219496 US9303033, O26, Table 37A, Compound 170 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219496 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219496&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335635 329994675 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383986 OCC[C@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1 InChI=1S/C21H22N8O3/c30-9-8-15(12-4-2-1-3-5-12)24-19-26-17-13(10-16-18(31)27-21(32)25-16)11-22-29(17)20(28-19)23-14-6-7-14/h1-5,10-11,14-15,30H,6-9H2,(H2,23,24,26,28)(H2,25,27,31,32)/b16-10-/t15-/m0/s1 PBHWIXCZBXWVFQ-HEUOVEHFSA-N 219497 US9303033, P26, Table 37A, Compound 171 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219497 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219497&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336141 329994676 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383987 CC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccncc1 InChI=1S/C19H19N9O2/c1-10(11-4-6-20-7-5-11)22-17-25-15-12(8-14-16(29)26-19(30)24-14)9-21-28(15)18(27-17)23-13-2-3-13/h4-10,13H,2-3H2,1H3,(H2,22,23,25,27)(H2,24,26,29,30)/b14-8- TWUNXDXSYKYODO-ZSOIEALJSA-N 219498 US9303033, Q26, Table 37A, Compound 172 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219498 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219498&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335379 329994677 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383988 Cc1nccn1-c1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C23H22N10O2/c1-13-24-8-9-32(13)17-6-2-14(3-7-17)11-25-21-29-19-15(10-18-20(34)30-23(35)28-18)12-26-33(19)22(31-21)27-16-4-5-16/h2-3,6-10,12,16H,4-5,11H2,1H3,(H2,25,27,29,31)(H2,28,30,34,35)/b18-10- SCWQNKQHIMICDD-ZDLGFXPLSA-N 219499 US9303033, R26, Table 37A, Compound 173 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219499 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219499&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335238 329994678 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383989 Cc1ccc(cc1)C(CO)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H22N8O3/c1-11-2-4-12(5-3-11)16(10-30)24-19-26-17-13(8-15-18(31)27-21(32)25-15)9-22-29(17)20(28-19)23-14-6-7-14/h2-5,8-9,14,16,30H,6-7,10H2,1H3,(H2,23,24,26,28)(H2,25,27,31,32)/b15-8- ZYPDEECPUJKYIU-NVNXTCNLSA-N 219500 US9303033, S26, Table 37A, Compound 174 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219500 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219500&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335836 329994679 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383990 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3ccc4OCCc4c3)nc12 InChI=1S/C21H20N8O3/c30-18-15(25-21(31)27-18)8-13-10-23-29-17(13)26-19(28-20(29)24-14-2-3-14)22-9-11-1-4-16-12(7-11)5-6-32-16/h1,4,7-8,10,14H,2-3,5-6,9H2,(H2,22,24,26,28)(H2,25,27,30,31)/b15-8- BQHSVIYGQBMKQK-NVNXTCNLSA-N 219501 US9303033, T26, Table 37A, Compound 175 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219501 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219501&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335824 329994680 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383991 CC(C)C(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1 InChI=1S/C22H24N8O2/c1-12(2)17(13-6-4-3-5-7-13)26-20-27-18-14(10-16-19(31)28-22(32)25-16)11-23-30(18)21(29-20)24-15-8-9-15/h3-7,10-12,15,17H,8-9H2,1-2H3,(H2,24,26,27,29)(H2,25,28,31,32)/b16-10- FDQGXSRGHXVWSQ-YBEGLDIGSA-N 219502 US9303033, U26, Table 37A, Compound 176 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219502 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219502&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336135 329994681 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383992 CCN(CC)S(=O)(=O)c1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)s1 InChI=1S/C21H25N9O4S2/c1-3-29(4-2)36(33,34)16-8-7-14(35-16)11-22-19-26-17-12(9-15-18(31)27-21(32)25-15)10-23-30(17)20(28-19)24-13-5-6-13/h7-10,13H,3-6,11H2,1-2H3,(H2,22,24,26,28)(H2,25,27,31,32)/b15-9- CHIAACNXFFNGPN-DHDCSXOGSA-N 219503 US9303033, V26, Table 37A, Compound 177 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219503 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219503&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336025 329994682 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383993 CC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccco1 InChI=1S/C18H18N8O3/c1-9(13-3-2-6-29-13)20-16-23-14-10(7-12-15(27)24-18(28)22-12)8-19-26(14)17(25-16)21-11-4-5-11/h2-3,6-9,11H,4-5H2,1H3,(H2,20,21,23,25)(H2,22,24,27,28)/b12-7- QVHOWIYXXSOEIV-GHXNOFRVSA-N 219504 US9303033, W26, Table 37A, Compound 178 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219504 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219504&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336137 329994683 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383994 COc1ccccc1[C@H](C)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H22N8O3/c1-11(14-5-3-4-6-16(14)32-2)23-19-26-17-12(9-15-18(30)27-21(31)25-15)10-22-29(17)20(28-19)24-13-7-8-13/h3-6,9-11,13H,7-8H2,1-2H3,(H2,23,24,26,28)(H2,25,27,30,31)/b15-9-/t11-/m0/s1 KYXOTCZXUZWCFU-GPILYODUSA-N 219505 US9303033, X26, Table 37A, Compound 179 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219505 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219505&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336139 329994684 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383995 CN(C)C(=O)c1cccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C22H23N9O3/c1-30(2)19(33)13-5-3-4-12(8-13)10-23-20-27-17-14(9-16-18(32)28-22(34)26-16)11-24-31(17)21(29-20)25-15-6-7-15/h3-5,8-9,11,15H,6-7,10H2,1-2H3,(H2,23,25,27,29)(H2,26,28,32,34)/b16-9- DHIPIIGMLFYTDK-SXGWCWSVSA-N 219506 US9303033, Y26, Table 37A, Compound 180 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219506 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219506&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335393 329994685 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383996 C[C@@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1cccc2ccccc12 InChI=1S/C24H22N8O2/c1-13(17-8-4-6-14-5-2-3-7-18(14)17)26-22-29-20-15(11-19-21(33)30-24(34)28-19)12-25-32(20)23(31-22)27-16-9-10-16/h2-8,11-13,16H,9-10H2,1H3,(H2,26,27,29,31)(H2,28,30,33,34)/b19-11-/t13-/m1/s1 KUSMLLAJLSJLKF-LPXFMOJISA-N 219507 US9303033, Z26, Table 37A, Compound 181 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219507 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219507&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336140 329994686 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383997 Fc1cc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)ccc1C(F)(F)F InChI=1S/C20H16F4N8O2/c21-13-5-9(1-4-12(13)20(22,23)24)7-25-17-29-15-10(6-14-16(33)30-19(34)28-14)8-26-32(15)18(31-17)27-11-2-3-11/h1,4-6,8,11H,2-3,7H2,(H2,25,27,29,31)(H2,28,30,33,34)/b14-6- YHYTUMOTCPNAGM-NSIKDUERSA-N 219508 US9303033, A27, Table 37A, Compound 182 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219508 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219508&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314497 329994687 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383998 Oc1cccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C19H18N8O3/c28-13-3-1-2-10(6-13)8-20-17-24-15-11(7-14-16(29)25-19(30)23-14)9-21-27(15)18(26-17)22-12-4-5-12/h1-3,6-7,9,12,28H,4-5,8H2,(H2,20,22,24,26)(H2,23,25,29,30)/b14-7- HBBNWQWVFQWZEW-AUWJEWJLSA-N 219509 US9303033, B27, Table 37A, Compound 183 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219509&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315013 329994688 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 383999 Brc1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C19H17BrN8O2/c20-12-3-1-10(2-4-12)8-21-17-25-15-11(7-14-16(29)26-19(30)24-14)9-22-28(15)18(27-17)23-13-5-6-13/h1-4,7,9,13H,5-6,8H2,(H2,21,23,25,27)(H2,24,26,29,30)/b14-7- BEPDRFLIJQNREV-AUWJEWJLSA-N 219510 US9303033, C27, Table 37A, Compound 184 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219510 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219510&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89888213 329994689 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384000 OC(=O)C(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1F InChI=1S/C20H17FN8O4/c21-12-4-2-1-3-11(12)14(17(31)32)25-18-26-15-9(7-13-16(30)27-20(33)24-13)8-22-29(15)19(28-18)23-10-5-6-10/h1-4,7-8,10,14H,5-6H2,(H,31,32)(H2,23,25,26,28)(H2,24,27,30,33)/b13-7- RBULCCYGRRYQEP-QPEQYQDCSA-N 219511 US9303033, D27, Table 37A, Compound 185 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219511 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219511&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314959 329994690 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384001 Ic1cccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C19H17IN8O2/c20-12-3-1-2-10(6-12)8-21-17-25-15-11(7-14-16(29)26-19(30)24-14)9-22-28(15)18(27-17)23-13-4-5-13/h1-3,6-7,9,13H,4-5,8H2,(H2,21,23,25,27)(H2,24,26,29,30)/b14-7- QGRWCOKASMSYHG-AUWJEWJLSA-N 219512 US9303033, E27, Table 37A, Compound 186 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219512 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219512&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335203 329994691 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384002 C[C@@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccc(Br)cc1 InChI=1S/C20H19BrN8O2/c1-10(11-2-4-13(21)5-3-11)23-18-26-16-12(8-15-17(30)27-20(31)25-15)9-22-29(16)19(28-18)24-14-6-7-14/h2-5,8-10,14H,6-7H2,1H3,(H2,23,24,26,28)(H2,25,27,30,31)/b15-8-/t10-/m1/s1 WRCZKPXIMWFIMW-IIBSKXHVSA-N 219513 US9303033, F27, Table 37A, Compound 187 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219513 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219513&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335401 329994692 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384003 OC(=O)c1cc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)ccc1O InChI=1S/C20H18N8O5/c29-14-4-1-9(5-12(14)17(31)32)7-21-18-25-15-10(6-13-16(30)26-20(33)24-13)8-22-28(15)19(27-18)23-11-2-3-11/h1,4-6,8,11,29H,2-3,7H2,(H,31,32)(H2,21,23,25,27)(H2,24,26,30,33)/b13-6- QJTBNTATNUDHKO-MLPAPPSSSA-N 219514 US9303033, G27, Table 37A, Compound 188 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219514 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219514&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336144 329994693 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384004 CCCC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1 InChI=1S/C22H24N8O2/c1-2-6-16(13-7-4-3-5-8-13)25-20-27-18-14(11-17-19(31)28-22(32)26-17)12-23-30(18)21(29-20)24-15-9-10-15/h3-5,7-8,11-12,15-16H,2,6,9-10H2,1H3,(H2,24,25,27,29)(H2,26,28,31,32)/b17-11- OJCXZGUYNKGKIH-BOPFTXTBSA-N 219515 US9303033, H27, Table 37A, Compound 189 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219515 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219515&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335400 329994694 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384005 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3cccc(c3)N3CCCCC3)nc12 InChI=1S/C24H27N9O2/c34-21-19(28-24(35)30-21)12-16-14-26-33-20(16)29-22(31-23(33)27-17-7-8-17)25-13-15-5-4-6-18(11-15)32-9-2-1-3-10-32/h4-6,11-12,14,17H,1-3,7-10,13H2,(H2,25,27,29,31)(H2,28,30,34,35)/b19-12- NUXDVCIOTRTNLS-UNOMPAQXSA-N 219516 US9303033, I27, Table 37A, Compound 190 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219516 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219516&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315080 329994695 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384006 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3nc4ccccc4s3)nc12 InChI=1S/C20H17N9O2S/c30-17-13(25-20(31)27-17)7-10-8-22-29-16(10)26-18(28-19(29)23-11-5-6-11)21-9-15-24-12-3-1-2-4-14(12)32-15/h1-4,7-8,11H,5-6,9H2,(H2,21,23,26,28)(H2,25,27,30,31)/b13-7- REGZERZGKNCGAP-QPEQYQDCSA-N 219517 US9303033, J27, Table 37A, Compound 191 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219517 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219517&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335403 329994696 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384007 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(N[C@H]3CCc4ccccc34)nc12 InChI=1S/C21H20N8O2/c30-18-16(25-21(31)27-18)9-12-10-22-29-17(12)26-19(28-20(29)23-13-6-7-13)24-15-8-5-11-3-1-2-4-14(11)15/h1-4,9-10,13,15H,5-8H2,(H2,23,24,26,28)(H2,25,27,30,31)/b16-9-/t15-/m0/s1 OXDPWRLJMBDTDO-HVVQPJKBSA-N 219518 US9303033, K27, Table 37A, Compound 192 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219518&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335839 329994697 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384008 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3ccc4OCCCOc4c3)nc12 InChI=1S/C22H22N8O4/c31-19-15(26-22(32)28-19)9-13-11-24-30-18(13)27-20(29-21(30)25-14-3-4-14)23-10-12-2-5-16-17(8-12)34-7-1-6-33-16/h2,5,8-9,11,14H,1,3-4,6-7,10H2,(H2,23,25,27,29)(H2,26,28,31,32)/b15-9- LEWJTNHNRNMFRP-DHDCSXOGSA-N 219519 US9303033, L27, Table 37A, Compound 193 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219519 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219519&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335636 329994698 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384009 C[C@@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccc(Cl)cc1 InChI=1S/C20H19ClN8O2/c1-10(11-2-4-13(21)5-3-11)23-18-26-16-12(8-15-17(30)27-20(31)25-15)9-22-29(16)19(28-18)24-14-6-7-14/h2-5,8-10,14H,6-7H2,1H3,(H2,23,24,26,28)(H2,25,27,30,31)/b15-8-/t10-/m1/s1 XBLZKWARYFXIKW-IIBSKXHVSA-N 219520 US9303033, M27, Table 37A, Compound 194 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219520 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219520&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335640 329994699 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384010 C[C@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccc2ccccc2c1 InChI=1S/C24H22N8O2/c1-13(15-7-6-14-4-2-3-5-16(14)10-15)26-22-29-20-17(11-19-21(33)30-24(34)28-19)12-25-32(20)23(31-22)27-18-8-9-18/h2-7,10-13,18H,8-9H2,1H3,(H2,26,27,29,31)(H2,28,30,33,34)/b19-11-/t13-/m0/s1 QNCLMSLBBOZJSS-JFENUBAZSA-N 219521 US9303033, N27, Table 37A, Compound 195 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219521 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219521&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314594 329994700 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384011 Oc1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C19H18N8O3/c28-13-5-1-10(2-6-13)8-20-17-24-15-11(7-14-16(29)25-19(30)23-14)9-21-27(15)18(26-17)22-12-3-4-12/h1-2,5-7,9,12,28H,3-4,8H2,(H2,20,22,24,26)(H2,23,25,29,30)/b14-7- MFZXXWZVHDTUOV-AUWJEWJLSA-N 219522 US9303033, O27, Table 37A, Compound 196 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219522 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219522&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335634 329994701 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384012 O[C@@H]1Cc2ccccc2[C@H]1Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H20N8O3/c30-15-8-10-3-1-2-4-13(10)16(15)25-19-26-17-11(7-14-18(31)27-21(32)24-14)9-22-29(17)20(28-19)23-12-5-6-12/h1-4,7,9,12,15-16,30H,5-6,8H2,(H2,23,25,26,28)(H2,24,27,31,32)/b14-7-/t15-,16-/m1/s1 IFVKGXXFFHIRNY-IAGRGRHTSA-N 219523 US9303033, P27, Table 37A, Compound 197 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219523 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219523&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335838 329994702 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384013 Fc1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c(c1)C(F)(F)F InChI=1S/C20H16F4N8O2/c21-11-2-1-9(13(6-11)20(22,23)24)7-25-17-29-15-10(5-14-16(33)30-19(34)28-14)8-26-32(15)18(31-17)27-12-3-4-12/h1-2,5-6,8,12H,3-4,7H2,(H2,25,27,29,31)(H2,28,30,33,34)/b14-5- GEFCSCRAICUSBR-RZNTYIFUSA-N 219524 US9303033, Q27, Table 37A, Compound 198 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219524 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219524&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336019 329994703 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384014 Cc1nn(C)c(C)c1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H22N10O2/c1-9-13(10(2)28(3)27-9)8-20-17-24-15-11(6-14-16(30)25-19(31)23-14)7-21-29(15)18(26-17)22-12-4-5-12/h6-7,12H,4-5,8H2,1-3H3,(H2,20,22,24,26)(H2,23,25,30,31)/b14-6- YENMXFILGREAFI-NSIKDUERSA-N 219525 US9303033, R27, Table 37A, Compound 199 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219525 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219525&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89888225 329994704 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384015 CN1CCN(CC1)c1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C24H28N10O2/c1-32-8-10-33(11-9-32)18-6-2-15(3-7-18)13-25-22-29-20-16(12-19-21(35)30-24(36)28-19)14-26-34(20)23(31-22)27-17-4-5-17/h2-3,6-7,12,14,17H,4-5,8-11,13H2,1H3,(H2,25,27,29,31)(H2,28,30,35,36)/b19-12- BWBTUOQGWCYWFR-UNOMPAQXSA-N 219526 US9303033, S27, Table 37A, Compound 200 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219526 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219526&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335206 329994705 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384016 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NC3CCCc4ncccc34)nc12 InChI=1S/C21H21N9O2/c31-18-16(26-21(32)28-18)9-11-10-23-30-17(11)27-19(29-20(30)24-12-6-7-12)25-15-5-1-4-14-13(15)3-2-8-22-14/h2-3,8-10,12,15H,1,4-7H2,(H2,24,25,27,29)(H2,26,28,31,32)/b16-9- DFHLNXJTZILSAD-SXGWCWSVSA-N 219527 US9303033, T27, Table 37A, Compound 201 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219527 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219527&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335840 329994706 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384017 CN(C)Cc1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C22H25N9O2/c1-30(2)12-14-5-3-13(4-6-14)10-23-20-27-18-15(9-17-19(32)28-22(33)26-17)11-24-31(18)21(29-20)25-16-7-8-16/h3-6,9,11,16H,7-8,10,12H2,1-2H3,(H2,23,25,27,29)(H2,26,28,32,33)/b17-9- JHCOQXPINSAOAO-MFOYZWKCSA-N 219528 US9303033, U27, Table 37A, Compound 202 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219528 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219528&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 124222771 329994707 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384018 Fc1cc(Br)ccc1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H16BrFN8O2/c20-11-2-1-9(13(21)6-11)7-22-17-26-15-10(5-14-16(30)27-19(31)25-14)8-23-29(15)18(28-17)24-12-3-4-12/h1-2,5-6,8,12H,3-4,7H2,(H2,22,24,26,28)(H2,25,27,30,31)/b14-5- ULVKVOQLACKQGH-RZNTYIFUSA-N 219529 US9303033, V27, Table 37A, Compound 203 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219529 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219529&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89888227 329994708 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384019 Clc1ccccc1C(CC(=O)N1CCCC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C25H26ClN9O3/c26-17-6-2-1-5-16(17)18(12-20(36)34-9-3-4-10-34)29-23-31-21-14(11-19-22(37)32-25(38)30-19)13-27-35(21)24(33-23)28-15-7-8-15/h1-2,5-6,11,13,15,18H,3-4,7-10,12H2,(H2,28,29,31,33)(H2,30,32,37,38)/b19-11- HODYRNLBQJLNRG-ODLFYWEKSA-N 219530 US9303033, W27, Table 37A, Compound 204 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219530 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219530&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336022 329994709 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384020 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3cccc4OCCOc34)nc12 InChI=1S/C21H20N8O4/c30-18-14(25-21(31)27-18)8-12-10-23-29-17(12)26-19(28-20(29)24-13-4-5-13)22-9-11-2-1-3-15-16(11)33-7-6-32-15/h1-3,8,10,13H,4-7,9H2,(H2,22,24,26,28)(H2,25,27,30,31)/b14-8- BHWGFTRAYRIOPU-ZSOIEALJSA-N 219531 US9303033, X27, Table 37A, Compound 205 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219531 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219531&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314053 329994710 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384021 CS(=O)(=O)c1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C20H20N8O4S/c1-33(31,32)14-6-2-11(3-7-14)9-21-18-25-16-12(8-15-17(29)26-20(30)24-15)10-22-28(16)19(27-18)23-13-4-5-13/h2-3,6-8,10,13H,4-5,9H2,1H3,(H2,21,23,25,27)(H2,24,26,29,30)/b15-8- AQASEWBGZDZRIF-NVNXTCNLSA-N 219532 US9303033, Y27, Table 37A, Compound 206 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219532 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219532&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335201 329994711 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384022 CC(C)Oc1cccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C22H24N8O3/c1-12(2)33-16-5-3-4-13(8-16)10-23-20-27-18-14(9-17-19(31)28-22(32)26-17)11-24-30(18)21(29-20)25-15-6-7-15/h3-5,8-9,11-12,15H,6-7,10H2,1-2H3,(H2,23,25,27,29)(H2,26,28,31,32)/b17-9- LWDMOJBMTAUNJO-MFOYZWKCSA-N 219533 US9303033, Z27, Table 37A, Compound 207 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219533 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219533&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89888240 329994712 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384023 CSc1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C20H20N8O2S/c1-31-14-6-2-11(3-7-14)9-21-18-25-16-12(8-15-17(29)26-20(30)24-15)10-22-28(16)19(27-18)23-13-4-5-13/h2-3,6-8,10,13H,4-5,9H2,1H3,(H2,21,23,25,27)(H2,24,26,29,30)/b15-8- CKMKCQFVYBPGMH-NVNXTCNLSA-N 219534 US9303033, A28, Table 37A, Compound 208 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219534&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89888226 329994713 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384024 OCCC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1 InChI=1S/C21H22N8O3/c30-9-8-15(12-4-2-1-3-5-12)24-19-26-17-13(10-16-18(31)27-21(32)25-16)11-22-29(17)20(28-19)23-14-6-7-14/h1-5,10-11,14-15,30H,6-9H2,(H2,23,24,26,28)(H2,25,27,31,32)/b16-10- PBHWIXCZBXWVFQ-YBEGLDIGSA-N 219535 US9303033, B28, Table 37A, Compound 209 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219535 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219535&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335190 329994714 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384025 COc1ccc(cc1)[C@@H](C)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H22N8O3/c1-11(12-3-7-15(32-2)8-4-12)23-19-26-17-13(9-16-18(30)27-21(31)25-16)10-22-29(17)20(28-19)24-14-5-6-14/h3-4,7-11,14H,5-6H2,1-2H3,(H2,23,24,26,28)(H2,25,27,30,31)/b16-9-/t11-/m1/s1 JLPLVKRLRGSRQO-WIWNTQSISA-N 219536 US9303033, C28, Table 37A, Compound 210 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219536 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219536&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89888242 329994715 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384026 C[C@@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccc2ccccc2c1 InChI=1S/C24H22N8O2/c1-13(15-7-6-14-4-2-3-5-16(14)10-15)26-22-29-20-17(11-19-21(33)30-24(34)28-19)12-25-32(20)23(31-22)27-18-8-9-18/h2-7,10-13,18H,8-9H2,1H3,(H2,26,27,29,31)(H2,28,30,33,34)/b19-11-/t13-/m1/s1 QNCLMSLBBOZJSS-LPXFMOJISA-N 219537 US9303033, D28, Table 37A, Compound 211 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219537 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219537&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313816 329994716 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384027 Fc1ccc(F)c(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C19H16F2N8O2/c20-11-1-4-13(21)9(5-11)7-22-17-26-15-10(6-14-16(30)27-19(31)25-14)8-23-29(15)18(28-17)24-12-2-3-12/h1,4-6,8,12H,2-3,7H2,(H2,22,24,26,28)(H2,25,27,30,31)/b14-6- VSHONIFCSKZVJW-NSIKDUERSA-N 219538 US9303033, E28, Table 37A, Compound 212 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219538 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219538&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335627 329994717 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384028 C[C@@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccn1 InChI=1S/C19H19N9O2/c1-10(13-4-2-3-7-20-13)22-17-25-15-11(8-14-16(29)26-19(30)24-14)9-21-28(15)18(27-17)23-12-5-6-12/h2-4,7-10,12H,5-6H2,1H3,(H2,22,23,25,27)(H2,24,26,29,30)/b14-8-/t10-/m1/s1 UATGVDJLQLGXHO-DOQDJBIESA-N 219539 US9303033, F28, Table 37A, Compound 213 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219539 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219539&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336040 329994718 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384029 OC(=O)Cc1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C21H20N8O4/c30-16(31)7-11-1-3-12(4-2-11)9-22-19-26-17-13(8-15-18(32)27-21(33)25-15)10-23-29(17)20(28-19)24-14-5-6-14/h1-4,8,10,14H,5-7,9H2,(H,30,31)(H2,22,24,26,28)(H2,25,27,32,33)/b15-8- GRBJORLMOFKNTG-NVNXTCNLSA-N 219540 US9303033, G28, Table 37A, Compound 214 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219540 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219540&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335844 329994719 C03768 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384030 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3ccccc3C#N)nc12 InChI=1S/C20H17N9O2/c21-8-11-3-1-2-4-12(11)9-22-18-26-16-13(7-15-17(30)27-20(31)25-15)10-23-29(16)19(28-18)24-14-5-6-14/h1-4,7,10,14H,5-6,9H2,(H2,22,24,26,28)(H2,25,27,30,31)/b15-7- JUWLVCPAYHGWRD-CHHVJCJISA-N 219541 US9303033, H28, Table 37A, Compound 215 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219541 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219541&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314572 329994720 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384031 CN(C)c1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C21H23N9O2/c1-29(2)15-7-3-12(4-8-15)10-22-19-26-17-13(9-16-18(31)27-21(32)25-16)11-23-30(17)20(28-19)24-14-5-6-14/h3-4,7-9,11,14H,5-6,10H2,1-2H3,(H2,22,24,26,28)(H2,25,27,31,32)/b16-9- WPZOIBMHGJLKHJ-SXGWCWSVSA-N 219542 US9303033, I28, Table 37A, Compound 216 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219542 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219542&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89888218 329994721 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384032 COc1cccc(c1)[C@H](C)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H22N8O3/c1-11(12-4-3-5-15(8-12)32-2)23-19-26-17-13(9-16-18(30)27-21(31)25-16)10-22-29(17)20(28-19)24-14-6-7-14/h3-5,8-11,14H,6-7H2,1-2H3,(H2,23,24,26,28)(H2,25,27,30,31)/b16-9-/t11-/m0/s1 USZDKSHBFYAPSQ-RCEBRVLHSA-N 219543 US9303033, J28, Table 37A, Compound 217 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219543&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313820 329994722 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384033 Clc1ccc(Cl)c(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C19H16Cl2N8O2/c20-11-1-4-13(21)9(5-11)7-22-17-26-15-10(6-14-16(30)27-19(31)25-14)8-23-29(15)18(28-17)24-12-2-3-12/h1,4-6,8,12H,2-3,7H2,(H2,22,24,26,28)(H2,25,27,30,31)/b14-6- PSKWZZIZPIAOTL-NSIKDUERSA-N 219544 US9303033, K28, Table 37A, Compound 218 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219544 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219544&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335202 329994723 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384034 COc1cccc(c1)[C@@H](C)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H22N8O3/c1-11(12-4-3-5-15(8-12)32-2)23-19-26-17-13(9-16-18(30)27-21(31)25-16)10-22-29(17)20(28-19)24-14-6-7-14/h3-5,8-11,14H,6-7H2,1-2H3,(H2,23,24,26,28)(H2,25,27,30,31)/b16-9-/t11-/m1/s1 USZDKSHBFYAPSQ-WIWNTQSISA-N 219545 US9303033, L28, Table 37A, Compound 219 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219545 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219545&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314979 329994724 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384035 COc1cc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc(OC)c1 InChI=1S/C21H22N8O4/c1-32-14-5-11(6-15(8-14)33-2)9-22-19-26-17-12(7-16-18(30)27-21(31)25-16)10-23-29(17)20(28-19)24-13-3-4-13/h5-8,10,13H,3-4,9H2,1-2H3,(H2,22,24,26,28)(H2,25,27,30,31)/b16-7- ADRVUIPENRJPAZ-APSNUPSMSA-N 219546 US9303033, M28, Table 37A, Compound 220 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219546 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219546&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314372 329994725 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384036 COc1ccc2CCC(Nc3nc(NC4CC4)n4ncc(\C=C5/NC(=O)NC5=O)c4n3)c2c1 InChI=1S/C22H22N8O3/c1-33-14-6-2-11-3-7-16(15(11)9-14)25-20-27-18-12(8-17-19(31)28-22(32)26-17)10-23-30(18)21(29-20)24-13-4-5-13/h2,6,8-10,13,16H,3-5,7H2,1H3,(H2,24,25,27,29)(H2,26,28,31,32)/b17-8- WUEHLVNUQUJCIH-IUXPMGMMSA-N 219547 US9303033, N28, Table 37A, Compound 221 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219547 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219547&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336153 329994726 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384037 C[C@@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccc(C)cc1 InChI=1S/C21H22N8O2/c1-11-3-5-13(6-4-11)12(2)23-19-26-17-14(9-16-18(30)27-21(31)25-16)10-22-29(17)20(28-19)24-15-7-8-15/h3-6,9-10,12,15H,7-8H2,1-2H3,(H2,23,24,26,28)(H2,25,27,30,31)/b16-9-/t12-/m1/s1 LJPJQDNRSMCNMI-DZZSIBQASA-N 219548 US9303033, O28, Table 37A, Compound 222 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219548 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219548&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336042 329994727 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384038 C[C@@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1Cl InChI=1S/C20H19ClN8O2/c1-10(13-4-2-3-5-14(13)21)23-18-26-16-11(8-15-17(30)27-20(31)25-15)9-22-29(16)19(28-18)24-12-6-7-12/h2-5,8-10,12H,6-7H2,1H3,(H2,23,24,26,28)(H2,25,27,30,31)/b15-8-/t10-/m1/s1 QBYHDBHMDWJNMS-IIBSKXHVSA-N 219549 US9303033, P28, Table 37A, Compound 223 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219549 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219549&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335407 329994728 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384039 Fc1ccc(cc1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C(F)(F)F InChI=1S/C20H16F4N8O2/c21-13-4-1-11(20(22,23)24)5-9(13)7-25-17-29-15-10(6-14-16(33)30-19(34)28-14)8-26-32(15)18(31-17)27-12-2-3-12/h1,4-6,8,12H,2-3,7H2,(H2,25,27,29,31)(H2,28,30,33,34)/b14-6- IUNUQCNYZHGVJZ-NSIKDUERSA-N 219550 US9303033, Q28, Table 37A, Compound 224 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219550 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219550&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314284 329994729 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384040 CC(C)CC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1 InChI=1S/C23H26N8O2/c1-13(2)10-17(14-6-4-3-5-7-14)26-21-28-19-15(11-18-20(32)29-23(33)27-18)12-24-31(19)22(30-21)25-16-8-9-16/h3-7,11-13,16-17H,8-10H2,1-2H3,(H2,25,26,28,30)(H2,27,29,32,33)/b18-11- MMAIRWPFEVMFJP-WQRHYEAKSA-N 219551 US9303033, R28, Table 37A, Compound 225 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219551&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335842 329994730 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384041 FC(F)(F)c1ccc(Cl)c(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C20H16ClF3N8O2/c21-13-4-1-11(20(22,23)24)5-9(13)7-25-17-29-15-10(6-14-16(33)30-19(34)28-14)8-26-32(15)18(31-17)27-12-2-3-12/h1,4-6,8,12H,2-3,7H2,(H2,25,27,29,31)(H2,28,30,33,34)/b14-6- YSIRJMUKYVJFOS-NSIKDUERSA-N 219552 US9303033, S28, Table 37A, Compound 226 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219552 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219552&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89888228 329994731 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384042 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3ccc(CN4CCOCC4)cc3)nc12 InChI=1S/C24H27N9O3/c34-21-19(28-24(35)30-21)11-17-13-26-33-20(17)29-22(31-23(33)27-18-5-6-18)25-12-15-1-3-16(4-2-15)14-32-7-9-36-10-8-32/h1-4,11,13,18H,5-10,12,14H2,(H2,25,27,29,31)(H2,28,30,34,35)/b19-11- PISBYIVSDHWODA-ODLFYWEKSA-N 219553 US9303033, T28, Table 37A, Compound 227 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219553 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219553&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335647 329994732 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384043 OC(=O)C(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1 InChI=1S/C20H18N8O4/c29-16-13(23-20(32)26-16)8-11-9-21-28-15(11)25-18(27-19(28)22-12-6-7-12)24-14(17(30)31)10-4-2-1-3-5-10/h1-5,8-9,12,14H,6-7H2,(H,30,31)(H2,22,24,25,27)(H2,23,26,29,32)/b13-8- LSRRLMNEUPIKCG-JYRVWZFOSA-N 219554 US9303033, U28, Table 37A, Compound 228 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219554 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219554&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335841 329994733 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384044 COc1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1OC InChI=1S/C21H22N8O4/c1-32-15-6-3-11(7-16(15)33-2)9-22-19-26-17-12(8-14-18(30)27-21(31)25-14)10-23-29(17)20(28-19)24-13-4-5-13/h3,6-8,10,13H,4-5,9H2,1-2H3,(H2,22,24,26,28)(H2,25,27,30,31)/b14-8- FNPIAVNBVYVKRM-ZSOIEALJSA-N 219555 US9303033, V28, Table 37A, Compound 229 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219555 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219555&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335398 329994734 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384045 OC(=O)[C@@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1 InChI=1S/C20H18N8O4/c29-16-13(23-20(32)26-16)8-11-9-21-28-15(11)25-18(27-19(28)22-12-6-7-12)24-14(17(30)31)10-4-2-1-3-5-10/h1-5,8-9,12,14H,6-7H2,(H,30,31)(H2,22,24,25,27)(H2,23,26,29,32)/b13-8-/t14-/m0/s1 LSRRLMNEUPIKCG-MQJVFOOVSA-N 219556 US9303033, W28, Table 37A, Compound 230 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219556 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219556&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335189 329994735 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384046 COc1ccc(OC)c(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C21H22N8O4/c1-32-14-5-6-16(33-2)11(7-14)9-22-19-26-17-12(8-15-18(30)27-21(31)25-15)10-23-29(17)20(28-19)24-13-3-4-13/h5-8,10,13H,3-4,9H2,1-2H3,(H2,22,24,26,28)(H2,25,27,30,31)/b15-8- VADBWBKHEVWCNI-NVNXTCNLSA-N 219557 US9303033, X28, Table 37A, Compound 231 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219557&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335404 329994736 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384047 Brc1cccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C19H17BrN8O2/c20-12-3-1-2-10(6-12)8-21-17-25-15-11(7-14-16(29)26-19(30)24-14)9-22-28(15)18(27-17)23-13-4-5-13/h1-3,6-7,9,13H,4-5,8H2,(H2,21,23,25,27)(H2,24,26,29,30)/b14-7- MQJABLLMZLNGNA-AUWJEWJLSA-N 219558 US9303033, Y28, Table 37A, Compound 232 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219558&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336143 329994737 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384048 Cc1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)o1 InChI=1S/C18H18N8O3/c1-9-2-5-12(29-9)8-19-16-23-14-10(6-13-15(27)24-18(28)22-13)7-20-26(14)17(25-16)21-11-3-4-11/h2,5-7,11H,3-4,8H2,1H3,(H2,19,21,23,25)(H2,22,24,27,28)/b13-6- DRZPXLBQDPRBDV-MLPAPPSSSA-N 219559 US9303033, Z28, Table 37A, Compound 233 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219559 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219559&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336147 329994738 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384049 Clc1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c(Cl)c1 InChI=1S/C19H16Cl2N8O2/c20-11-2-1-9(13(21)6-11)7-22-17-26-15-10(5-14-16(30)27-19(31)25-14)8-23-29(15)18(28-17)24-12-3-4-12/h1-2,5-6,8,12H,3-4,7H2,(H2,22,24,26,28)(H2,25,27,30,31)/b14-5- SBIPMWPTTMEOBR-RZNTYIFUSA-N 219560 US9303033, A29, Table 37A, Compound 234 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219560 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219560&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335845 329994739 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384050 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3ccccc3-n3ccnc3)nc12 InChI=1S/C22H20N10O2/c33-19-16(27-22(34)29-19)9-14-11-25-32-18(14)28-20(30-21(32)26-15-5-6-15)24-10-13-3-1-2-4-17(13)31-8-7-23-12-31/h1-4,7-9,11-12,15H,5-6,10H2,(H2,24,26,28,30)(H2,27,29,33,34)/b16-9- DBOIUWDDLAKXNK-SXGWCWSVSA-N 219561 US9303033, B29, Table 37A, Compound 235 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219561 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219561&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336039 329994740 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384051 FC(F)(F)Sc1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C20H17F3N8O2S/c21-20(22,23)34-13-5-1-10(2-6-13)8-24-17-28-15-11(7-14-16(32)29-19(33)27-14)9-25-31(15)18(30-17)26-12-3-4-12/h1-2,5-7,9,12H,3-4,8H2,(H2,24,26,28,30)(H2,27,29,32,33)/b14-7- BDEBFYMBQPQSED-AUWJEWJLSA-N 219562 US9303033, C29, Table 37A, Compound 236 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219562 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219562&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335406 329994741 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384052 CC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccc(Br)cc1 InChI=1S/C20H19BrN8O2/c1-10(11-2-4-13(21)5-3-11)23-18-26-16-12(8-15-17(30)27-20(31)25-15)9-22-29(16)19(28-18)24-14-6-7-14/h2-5,8-10,14H,6-7H2,1H3,(H2,23,24,26,28)(H2,25,27,30,31)/b15-8- WRCZKPXIMWFIMW-NVNXTCNLSA-N 219563 US9303033, D29, Table 37A, Compound 237 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219563&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335642 329994742 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384053 C[C@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccc(Br)cc1 InChI=1S/C20H19BrN8O2/c1-10(11-2-4-13(21)5-3-11)23-18-26-16-12(8-15-17(30)27-20(31)25-15)9-22-29(16)19(28-18)24-14-6-7-14/h2-5,8-10,14H,6-7H2,1H3,(H2,23,24,26,28)(H2,25,27,30,31)/b15-8-/t10-/m0/s1 WRCZKPXIMWFIMW-SOOGHKCXSA-N 219564 US9303033, E29, Table 37A, Compound 238 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219564 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219564&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335410 329994743 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384054 FC(F)(F)Oc1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C20H17F3N8O3/c21-20(22,23)34-13-5-1-10(2-6-13)8-24-17-28-15-11(7-14-16(32)29-19(33)27-14)9-25-31(15)18(30-17)26-12-3-4-12/h1-2,5-7,9,12H,3-4,8H2,(H2,24,26,28,30)(H2,27,29,32,33)/b14-7- JSAQXKANKRCVJR-AUWJEWJLSA-N 219565 US9303033, F29, Table 37A, Compound 239 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219565 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219565&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335195 329994744 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384055 CC1CN(CC(C)O1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H22N8O3/c1-9-7-25(8-10(2)29-9)16-22-14-11(5-13-15(27)23-18(28)21-13)6-19-26(14)17(24-16)20-12-3-4-12/h5-6,9-10,12H,3-4,7-8H2,1-2H3,(H,20,22,24)(H2,21,23,27,28)/b13-5- JHHARPPEXBKILV-ACAGNQJTSA-N 219566 US9303033, G29, Table 37A, Compound 240 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219566 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219566&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336151 329994745 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384056 C[C@H]1CN(C[C@@H](C)O1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H22N8O3/c1-9-7-25(8-10(2)29-9)16-22-14-11(5-13-15(27)23-18(28)21-13)6-19-26(14)17(24-16)20-12-3-4-12/h5-6,9-10,12H,3-4,7-8H2,1-2H3,(H,20,22,24)(H2,21,23,27,28)/b13-5-/t9-,10+ JHHARPPEXBKILV-XNFJCXGQSA-N 219567 US9303033, H29, Table 37A, Compound 241 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219567 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219567&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335646 329994746 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384057 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)N1CCC(CC1)c1cccc(c1)C#N InChI=1S/C24H23N9O2/c25-12-14-2-1-3-16(10-14)15-6-8-32(9-7-15)22-29-20-17(11-19-21(34)30-24(35)28-19)13-26-33(20)23(31-22)27-18-4-5-18/h1-3,10-11,13,15,18H,4-9H2,(H,27,29,31)(H2,28,30,34,35)/b19-11- HRGDMPBIKLPVMW-ODLFYWEKSA-N 219568 US9303033, I29, Table 37A, Compound 242 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219568&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335849 329994747 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384058 FC1(F)CCC(CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H20F2N8O2/c19-18(20)5-3-11(4-6-18)22-15-25-13-9(7-12-14(29)26-17(30)24-12)8-21-28(13)16(27-15)23-10-1-2-10/h7-8,10-11H,1-6H2,(H2,22,23,25,27)(H2,24,26,29,30)/b12-7- MHRQDUOISZBBDC-GHXNOFRVSA-N 219569 US9303033, J29, Table 37A, Compound 243 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219569&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335211 329994748 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384059 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)N(CCC#N)C1CCCC1 InChI=1S/C20H23N9O2/c21-8-3-9-28(14-4-1-2-5-14)18-25-16-12(10-15-17(30)26-20(31)24-15)11-22-29(16)19(27-18)23-13-6-7-13/h10-11,13-14H,1-7,9H2,(H,23,25,27)(H2,24,26,30,31)/b15-10- NTVYWJDIJVZXAT-GDNBJRDFSA-N 219570 US9303033, K29, Table 37A, Compound 244 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219570&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336038 329994749 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384060 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(N[C@H]3CCOC3)nc12 InChI=1S/C16H18N8O3/c25-13-11(20-16(26)22-13)5-8-6-17-24-12(8)21-14(18-10-3-4-27-7-10)23-15(24)19-9-1-2-9/h5-6,9-10H,1-4,7H2,(H2,18,19,21,23)(H2,20,22,25,26)/b11-5-/t10-/m0/s1 DPVWODJFCUAEBF-QIMWGGGBSA-N 219571 US9303033, L29, Table 37A, Compound 245 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219571&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335223 329994750 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384061 CN(C)S(=O)(=O)N1CCN(CC1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H24N10O4S/c1-25(2)33(31,32)27-7-5-26(6-8-27)16-22-14-11(9-13-15(29)23-18(30)21-13)10-19-28(14)17(24-16)20-12-3-4-12/h9-10,12H,3-8H2,1-2H3,(H,20,22,24)(H2,21,23,29,30)/b13-9- GCBMFVGRFIYUMA-LCYFTJDESA-N 219572 US9303033, M29, Table 37A, Compound 246 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219572 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219572&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336152 329994751 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384062 FC1(F)CN(C1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C15H14F2N8O2/c16-15(17)5-24(6-15)12-21-10-7(3-9-11(26)22-14(27)20-9)4-18-25(10)13(23-12)19-8-1-2-8/h3-4,8H,1-2,5-6H2,(H,19,21,23)(H2,20,22,26,27)/b9-3- RIKHZDKCOHIIDO-OQFOIZHKSA-N 219573 US9303033, N29, Table 37A, Compound 247 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219573&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335851 329994752 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384063 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)N1CCN(Cc2cccc(c2)C#N)CC1 InChI=1S/C24H24N10O2/c25-12-15-2-1-3-16(10-15)14-32-6-8-33(9-7-32)22-29-20-17(11-19-21(35)30-24(36)28-19)13-26-34(20)23(31-22)27-18-4-5-18/h1-3,10-11,13,18H,4-9,14H2,(H,27,29,31)(H2,28,30,35,36)/b19-11- PWLNOUQPRFYILH-ODLFYWEKSA-N 219574 US9303033, O29, Table 37A, Compound 248 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219574&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335411 329994753 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384064 CN(Cc1ccccc1Br)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H19BrN8O2/c1-28(10-11-4-2-3-5-14(11)21)18-25-16-12(8-15-17(30)26-20(31)24-15)9-22-29(16)19(27-18)23-13-6-7-13/h2-5,8-9,13H,6-7,10H2,1H3,(H,23,25,27)(H2,24,26,30,31)/b15-8- ZAQOSXSMFYCRBY-NVNXTCNLSA-N 219575 US9303033, P29, Table 37A, Compound 249 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219575 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219575&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314242 329994754 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384065 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCCC3CCOCC3)nc12 InChI=1S/C19H24N8O3/c28-16-14(23-19(29)25-16)9-12-10-21-27-15(12)24-17(26-18(27)22-13-1-2-13)20-6-3-11-4-7-30-8-5-11/h9-11,13H,1-8H2,(H2,20,22,24,26)(H2,23,25,28,29)/b14-9- BOMDFCPATDUVIL-ZROIWOOFSA-N 219576 US9303033, Q29, Table 37A, Compound 250 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219576&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335656 329994755 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384066 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)N1CCC(CC1)C#N InChI=1S/C18H19N9O2/c19-8-10-3-5-26(6-4-10)16-23-14-11(7-13-15(28)24-18(29)22-13)9-20-27(14)17(25-16)21-12-1-2-12/h7,9-10,12H,1-6H2,(H,21,23,25)(H2,22,24,28,29)/b13-7- SIDSOLMJTIXXIX-QPEQYQDCSA-N 219577 US9303033, R29, Table 37A, Compound 251 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219577&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335225 329994756 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384067 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCC3COCCO3)nc12 InChI=1S/C17H20N8O4/c26-14-12(21-17(27)23-14)5-9-6-19-25-13(9)22-15(24-16(25)20-10-1-2-10)18-7-11-8-28-3-4-29-11/h5-6,10-11H,1-4,7-8H2,(H2,18,20,22,24)(H2,21,23,26,27)/b12-5- IPMWJDBGGZIYPT-XGICHPGQSA-N 219578 US9303033, S29, Table 37A, Compound 252 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219578&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336158 329994757 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384068 CN(Cc1ccc(Br)cc1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H19BrN8O2/c1-28(10-11-2-4-13(21)5-3-11)18-25-16-12(8-15-17(30)26-20(31)24-15)9-22-29(16)19(27-18)23-14-6-7-14/h2-5,8-9,14H,6-7,10H2,1H3,(H,23,25,27)(H2,24,26,30,31)/b15-8- RYBVFRHUYWJSRB-NVNXTCNLSA-N 219579 US9303033, T29, Table 37A, Compound 253 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219579 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219579&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335417 329994758 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384069 CC(C)(CN1CCOCC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H27N9O3/c1-20(2,11-28-5-7-32-8-6-28)27-17-24-15-12(9-14-16(30)25-19(31)23-14)10-21-29(15)18(26-17)22-13-3-4-13/h9-10,13H,3-8,11H2,1-2H3,(H2,22,24,26,27)(H2,23,25,30,31)/b14-9- QGTVKOSHHRGQDN-ZROIWOOFSA-N 219580 US9303033, U29, Table 37A, Compound 254 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219580 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219580&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335654 329994759 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384070 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)N1CCCN(CC1)c1ncccc1C#N InChI=1S/C23H23N11O2/c24-12-14-3-1-6-25-18(14)32-7-2-8-33(10-9-32)21-29-19-15(11-17-20(35)30-23(36)28-17)13-26-34(19)22(31-21)27-16-4-5-16/h1,3,6,11,13,16H,2,4-5,7-10H2,(H,27,29,31)(H2,28,30,35,36)/b17-11- XLWBLIGHDAXYBE-BOPFTXTBSA-N 219581 US9303033, V29, Table 37A, Compound 255 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219581 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219581&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336059 329994760 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384071 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)N1CCC(CC1)c1ccc(cc1)C#N InChI=1S/C24H23N9O2/c25-12-14-1-3-15(4-2-14)16-7-9-32(10-8-16)22-29-20-17(11-19-21(34)30-24(35)28-19)13-26-33(20)23(31-22)27-18-5-6-18/h1-4,11,13,16,18H,5-10H2,(H,27,29,31)(H2,28,30,34,35)/b19-11- LTEYBPKFRJDEKC-ODLFYWEKSA-N 219582 US9303033, W29, Table 37A, Compound 256 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219582 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219582&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335204 329994761 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384072 CN(Cc1ccc(cc1)-n1ccnc1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H22N10O2/c1-31(12-14-2-6-17(7-3-14)32-9-8-24-13-32)21-28-19-15(10-18-20(34)29-23(35)27-18)11-25-33(19)22(30-21)26-16-4-5-16/h2-3,6-11,13,16H,4-5,12H2,1H3,(H,26,28,30)(H2,27,29,34,35)/b18-10- COKRHGFKHXMNQU-ZDLGFXPLSA-N 219583 US9303033, X29, Table 37A, Compound 257 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219583 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219583&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335409 329994762 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384073 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)N1CCC(CC1)N1CCOCC1 InChI=1S/C21H27N9O3/c31-18-16(24-21(32)26-18)11-13-12-22-30-17(13)25-19(27-20(30)23-14-1-2-14)29-5-3-15(4-6-29)28-7-9-33-10-8-28/h11-12,14-15H,1-10H2,(H,23,25,27)(H2,24,26,31,32)/b16-11- HLVRZZOUIZLWMK-WJDWOHSUSA-N 219584 US9303033, Y29, Table 37A, Compound 258 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219584 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219584&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336160 329994763 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384074 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)N1CCCN(CC1)c1ccc(cn1)C#N InChI=1S/C23H23N11O2/c24-11-14-2-5-18(25-12-14)32-6-1-7-33(9-8-32)21-29-19-15(10-17-20(35)30-23(36)28-17)13-26-34(19)22(31-21)27-16-3-4-16/h2,5,10,12-13,16H,1,3-4,6-9H2,(H,27,29,31)(H2,28,30,35,36)/b17-10- PXDUAITWIWWKOS-YVLHZVERSA-N 219585 US9303033, Z29, Table 37A, Compound 259 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219585 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219585&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336036 329994764 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384075 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCCC#N)nc12 InChI=1S/C15H15N9O2/c16-4-1-5-17-13-21-11-8(6-10-12(25)22-15(26)20-10)7-18-24(11)14(23-13)19-9-2-3-9/h6-7,9H,1-3,5H2,(H2,17,19,21,23)(H2,20,22,25,26)/b10-6- BEANSVRNCBWGGG-POHAHGRESA-N 219586 US9303033, A30, Table 37A, Compound 260 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219586 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219586&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335641 329994765 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384076 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)N1CCN(CC1)c1ncccc1C#N InChI=1S/C22H21N11O2/c23-11-13-2-1-5-24-17(13)31-6-8-32(9-7-31)20-28-18-14(10-16-19(34)29-22(35)27-16)12-25-33(18)21(30-20)26-15-3-4-15/h1-2,5,10,12,15H,3-4,6-9H2,(H,26,28,30)(H2,27,29,34,35)/b16-10- BAQHEOSECNOPCO-YBEGLDIGSA-N 219587 US9303033, B30, Table 37A, Compound 261 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219587 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219587&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335191 329994766 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384077 C[C@H](N(CCO)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1 InChI=1S/C22H24N8O3/c1-13(14-5-3-2-4-6-14)29(9-10-31)20-26-18-15(11-17-19(32)27-22(33)25-17)12-23-30(18)21(28-20)24-16-7-8-16/h2-6,11-13,16,31H,7-10H2,1H3,(H,24,26,28)(H2,25,27,32,33)/b17-11-/t13-/m0/s1 CNFLPKDJDPEISO-MFVBVHDHSA-N 219588 US9303033, C30, Table 37A, Compound 262 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219588 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219588&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335848 329994767 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384078 CN(Cc1ccc(cc1)-n1cccn1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H22N10O2/c1-31(13-14-3-7-17(8-4-14)32-10-2-9-24-32)21-28-19-15(11-18-20(34)29-23(35)27-18)12-25-33(19)22(30-21)26-16-5-6-16/h2-4,7-12,16H,5-6,13H2,1H3,(H,26,28,30)(H2,27,29,34,35)/b18-11- UTXZILHISGBEGK-WQRHYEAKSA-N 219589 US9303033, D30, Table 37A, Compound 263 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219589 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219589&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335413 329994768 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384079 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)N1CCN(CC1)c1ccc(cn1)C#N InChI=1S/C22H21N11O2/c23-10-13-1-4-17(24-11-13)31-5-7-32(8-6-31)20-28-18-14(9-16-19(34)29-22(35)27-16)12-25-33(18)21(30-20)26-15-2-3-15/h1,4,9,11-12,15H,2-3,5-8H2,(H,26,28,30)(H2,27,29,34,35)/b16-9- LJXAYGXSYVBUEY-SXGWCWSVSA-N 219590 US9303033, E30, Table 37A, Compound 264 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219590 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219590&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335212 329994769 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384080 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)N(CCC#N)Cc1cccnc1 InChI=1S/C21H20N10O2/c22-6-2-8-30(12-13-3-1-7-23-10-13)19-27-17-14(9-16-18(32)28-21(33)26-16)11-24-31(17)20(29-19)25-15-4-5-15/h1,3,7,9-11,15H,2,4-5,8,12H2,(H,25,27,29)(H2,26,28,32,33)/b16-9- MXDRCSIKFLOGSM-SXGWCWSVSA-N 219591 US9303033, F30, Table 37A, Compound 265 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219591 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219591&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336047 329994770 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384081 CN(Cc1c(F)cccc1Cl)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H18ClFN8O2/c1-29(9-12-13(21)3-2-4-14(12)22)18-26-16-10(7-15-17(31)27-20(32)25-15)8-23-30(16)19(28-18)24-11-5-6-11/h2-4,7-8,11H,5-6,9H2,1H3,(H,24,26,28)(H2,25,27,31,32)/b15-7- SHOMGWGBCQJMSY-CHHVJCJISA-N 219592 US9303033, G30, Table 37A, Compound 266 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219592 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219592&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335645 329994771 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384082 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCCS(=O)(=O)N3CCCC3)nc12 InChI=1S/C18H23N9O4S/c28-15-13(22-18(29)24-15)9-11-10-20-27-14(11)23-16(25-17(27)21-12-3-4-12)19-5-8-32(30,31)26-6-1-2-7-26/h9-10,12H,1-8H2,(H2,19,21,23,25)(H2,22,24,28,29)/b13-9- ZAIVZMBQFHLSMR-LCYFTJDESA-N 219593 US9303033, H30, Table 37A, Compound 267 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219593&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335412 329994772 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384083 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)N1CCN(Cc2ccc(cc2)C#N)CC1 InChI=1S/C24H24N10O2/c25-12-15-1-3-16(4-2-15)14-32-7-9-33(10-8-32)22-29-20-17(11-19-21(35)30-24(36)28-19)13-26-34(20)23(31-22)27-18-5-6-18/h1-4,11,13,18H,5-10,14H2,(H,27,29,31)(H2,28,30,35,36)/b19-11- KLODVHLVXTVWMK-ODLFYWEKSA-N 219594 US9303033, I30, Table 37A, Compound 268 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219594&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336045 329994773 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384084 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)N1Cc2ccccc2C1 InChI=1S/C20H18N8O2/c29-17-15(23-20(30)25-17)7-13-8-21-28-16(13)24-18(26-19(28)22-14-5-6-14)27-9-11-3-1-2-4-12(11)10-27/h1-4,7-8,14H,5-6,9-10H2,(H,22,24,26)(H2,23,25,29,30)/b15-7- DUJTVRSDPJVZPR-CHHVJCJISA-N 219595 US9303033, J30, Table 37A, Compound 269 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219595 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219595&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335857 329994774 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384085 CN(Cc1cccc(F)c1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H19FN8O2/c1-28(10-11-3-2-4-13(21)7-11)18-25-16-12(8-15-17(30)26-20(31)24-15)9-22-29(16)19(27-18)23-14-5-6-14/h2-4,7-9,14H,5-6,10H2,1H3,(H,23,25,27)(H2,24,26,30,31)/b15-8- ZUWHWVYMMXMCQA-NVNXTCNLSA-N 219596 US9303033, K30, Table 37A, Compound 270 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219596 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219596&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313785 329994775 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384086 CN(Cc1cccc(Br)c1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H19BrN8O2/c1-28(10-11-3-2-4-13(21)7-11)18-25-16-12(8-15-17(30)26-20(31)24-15)9-22-29(16)19(27-18)23-14-5-6-14/h2-4,7-9,14H,5-6,10H2,1H3,(H,23,25,27)(H2,24,26,30,31)/b15-8- BOGOYDLLCRNXBF-NVNXTCNLSA-N 219597 US9303033, L30, Table 37A, Compound 271 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219597 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219597&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335854 329994776 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384087 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)N(CCC#N)C1CC1 InChI=1S/C18H19N9O2/c19-6-1-7-26(12-4-5-12)16-23-14-10(8-13-15(28)24-18(29)22-13)9-20-27(14)17(25-16)21-11-2-3-11/h8-9,11-12H,1-5,7H2,(H,21,23,25)(H2,22,24,28,29)/b13-8- ACGUUWNODOXDCB-JYRVWZFOSA-N 219598 US9303033, M30, Table 37A, Compound 272 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219598 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219598&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335208 329994777 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384088 CN(Cc1ccc(Cl)cc1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H19ClN8O2/c1-28(10-11-2-4-13(21)5-3-11)18-25-16-12(8-15-17(30)26-20(31)24-15)9-22-29(16)19(27-18)23-14-6-7-14/h2-5,8-9,14H,6-7,10H2,1H3,(H,23,25,27)(H2,24,26,30,31)/b15-8- KURWMNSCCMVIOZ-NVNXTCNLSA-N 219599 US9303033, N30, Table 37A, Compound 273 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219599 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219599&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335651 329994778 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384089 Cc1cc2ccccc2n1CCNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H23N9O2/c1-13-10-14-4-2-3-5-18(14)31(13)9-8-24-21-28-19-15(11-17-20(33)29-23(34)27-17)12-25-32(19)22(30-21)26-16-6-7-16/h2-5,10-12,16H,6-9H2,1H3,(H2,24,26,28,30)(H2,27,29,33,34)/b17-11- WRDWKUZCXGELOU-BOPFTXTBSA-N 219600 US9303033, O30, Table 37A, Compound 274 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219600 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219600&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335217 329994779 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384090 CN(Cc1ccccn1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H19N9O2/c1-27(10-13-4-2-3-7-20-13)17-24-15-11(8-14-16(29)25-19(30)23-14)9-21-28(15)18(26-17)22-12-5-6-12/h2-4,7-9,12H,5-6,10H2,1H3,(H,22,24,26)(H2,23,25,29,30)/b14-8- NMHTWELDHRMTPG-ZSOIEALJSA-N 219601 US9303033, P30, Table 37A, Compound 275 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219601&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335648 329994780 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384091 CN(Cc1ccncc1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H19N9O2/c1-27(10-11-4-6-20-7-5-11)17-24-15-12(8-14-16(29)25-19(30)23-14)9-21-28(15)18(26-17)22-13-2-3-13/h4-9,13H,2-3,10H2,1H3,(H,22,24,26)(H2,23,25,29,30)/b14-8- QSBBHYOPJVWVFM-ZSOIEALJSA-N 219602 US9303033, Q30, Table 37A, Compound 276 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219602 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219602&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335860 329994781 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384092 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)N1CCC(CC1)N1CCCCC1 InChI=1S/C22H29N9O2/c32-19-17(25-22(33)27-19)12-14-13-23-31-18(14)26-20(28-21(31)24-15-4-5-15)30-10-6-16(7-11-30)29-8-2-1-3-9-29/h12-13,15-16H,1-11H2,(H,24,26,28)(H2,25,27,32,33)/b17-12- SMAWZWIKVAQWAO-ATVHPVEESA-N 219603 US9303033, R30, Table 37A, Compound 277 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219603 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219603&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336052 329994782 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384093 C[C@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C1CCCCC1 InChI=1S/C20H26N8O2/c1-11(12-5-3-2-4-6-12)22-18-25-16-13(9-15-17(29)26-20(30)24-15)10-21-28(16)19(27-18)23-14-7-8-14/h9-12,14H,2-8H2,1H3,(H2,22,23,25,27)(H2,24,26,29,30)/b15-9-/t11-/m0/s1 KSLUVTMCDSRYAP-GPILYODUSA-N 219604 US9303033, S30, Table 37A, Compound 278 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219604 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219604&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335861 329994783 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384094 CN(Cc1ccccc1F)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H19FN8O2/c1-28(10-11-4-2-3-5-14(11)21)18-25-16-12(8-15-17(30)26-20(31)24-15)9-22-29(16)19(27-18)23-13-6-7-13/h2-5,8-9,13H,6-7,10H2,1H3,(H,23,25,27)(H2,24,26,30,31)/b15-8- XZUROVFJWBKPPY-NVNXTCNLSA-N 219605 US9303033, T30, Table 37A, Compound 279 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219605 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219605&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315026 329994784 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384095 CS(=O)(=O)N1CCN(CC1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C17H21N9O4S/c1-31(29,30)25-6-4-24(5-7-25)15-21-13-10(8-12-14(27)22-17(28)20-12)9-18-26(13)16(23-15)19-11-2-3-11/h8-9,11H,2-7H2,1H3,(H,19,21,23)(H2,20,22,27,28)/b12-8- UTAOWJVKFHDNCJ-WQLSENKSSA-N 219606 US9303033, U30, Table 37A, Compound 280 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219606 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219606&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89888219 329994785 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384096 Clc1cccc(OCCNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C20H19ClN8O3/c21-12-2-1-3-14(9-12)32-7-6-22-18-26-16-11(8-15-17(30)27-20(31)25-15)10-23-29(16)19(28-18)24-13-4-5-13/h1-3,8-10,13H,4-7H2,(H2,22,24,26,28)(H2,25,27,30,31)/b15-8- BQCBGRPRQUYQMC-NVNXTCNLSA-N 219607 US9303033, V30, Table 37A, Compound 281 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219607 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219607&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335658 329994786 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384097 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)N1CCc2ccc(cc2C1)C#N InChI=1S/C22H19N9O2/c23-9-12-1-2-13-5-6-30(11-15(13)7-12)20-27-18-14(8-17-19(32)28-22(33)26-17)10-24-31(18)21(29-20)25-16-3-4-16/h1-2,7-8,10,16H,3-6,11H2,(H,25,27,29)(H2,26,28,32,33)/b17-8- JBPVFSSFFMKMDZ-IUXPMGMMSA-N 219608 US9303033, W30, Table 37A, Compound 282 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219608 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219608&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335850 329994787 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384098 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)N1CCN(CCC#N)CC1 InChI=1S/C19H22N10O2/c20-4-1-5-27-6-8-28(9-7-27)17-24-15-12(10-14-16(30)25-19(31)23-14)11-21-29(15)18(26-17)22-13-2-3-13/h10-11,13H,1-3,5-9H2,(H,22,24,26)(H2,23,25,30,31)/b14-10- ONYGSUSZDADGDB-UVTDQMKNSA-N 219609 US9303033, X30, Table 37A, Compound 283 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219609 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219609&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335855 329994788 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384099 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCC3CCCOC3)nc12 InChI=1S/C18H22N8O3/c27-15-13(22-18(28)24-15)6-11-8-20-26-14(11)23-16(25-17(26)21-12-3-4-12)19-7-10-2-1-5-29-9-10/h6,8,10,12H,1-5,7,9H2,(H2,19,21,23,25)(H2,22,24,27,28)/b13-6- SVYBPUHXFTXBQH-MLPAPPSSSA-N 219610 US9303033, Y30, Table 37A, Compound 284 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219610 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219610&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335665 329994789 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384100 C[C@@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C1CCCCC1 InChI=1S/C20H26N8O2/c1-11(12-5-3-2-4-6-12)22-18-25-16-13(9-15-17(29)26-20(30)24-15)10-21-28(16)19(27-18)23-14-7-8-14/h9-12,14H,2-8H2,1H3,(H2,22,23,25,27)(H2,24,26,29,30)/b15-9-/t11-/m1/s1 KSLUVTMCDSRYAP-PDICVPPASA-N 219611 US9303033, Z30, Table 37A, Compound 285 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219611 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219611&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335254 329994790 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384101 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)N1CCN(CC1)c1ccc(cc1)C#N InChI=1S/C23H22N10O2/c24-12-14-1-5-17(6-2-14)31-7-9-32(10-8-31)21-28-19-15(11-18-20(34)29-23(35)27-18)13-25-33(19)22(30-21)26-16-3-4-16/h1-2,5-6,11,13,16H,3-4,7-10H2,(H,26,28,30)(H2,27,29,34,35)/b18-11- PAQWVDHAPOVVOY-WQRHYEAKSA-N 219612 US9303033, A31, Table 37A, Compound 286 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219612 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219612&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336057 329994791 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384102 Clc1ccc(OCCNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C20H19ClN8O3/c21-12-1-5-14(6-2-12)32-8-7-22-18-26-16-11(9-15-17(30)27-20(31)25-15)10-23-29(16)19(28-18)24-13-3-4-13/h1-2,5-6,9-10,13H,3-4,7-8H2,(H2,22,24,26,28)(H2,25,27,30,31)/b15-9- JGNOMFKXVROUDN-DHDCSXOGSA-N 219613 US9303033, B31, Table 37A, Compound 287 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219613 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219613&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336058 329994792 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384103 C[C@@H](N(CCO)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1 InChI=1S/C22H24N8O3/c1-13(14-5-3-2-4-6-14)29(9-10-31)20-26-18-15(11-17-19(32)27-22(33)25-17)12-23-30(18)21(28-20)24-16-7-8-16/h2-6,11-13,16,31H,7-10H2,1H3,(H,24,26,28)(H2,25,27,32,33)/b17-11-/t13-/m1/s1 CNFLPKDJDPEISO-GPLLRDDGSA-N 219614 US9303033, C31, Table 37A, Compound 288 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219614 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219614&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336061 329994793 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384104 CCS(=O)(=O)N1CCN(CC1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H23N9O4S/c1-2-32(30,31)26-7-5-25(6-8-26)16-22-14-11(9-13-15(28)23-18(29)21-13)10-19-27(14)17(24-16)20-12-3-4-12/h9-10,12H,2-8H2,1H3,(H,20,22,24)(H2,21,23,28,29)/b13-9- FTMQYORQYWVCCT-LCYFTJDESA-N 219615 US9303033, D31, Table 37A, Compound 289 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219615 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219615&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89888244 329994794 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384105 CCN(Cc1ccccc1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H22N8O2/c1-2-28(12-13-6-4-3-5-7-13)19-25-17-14(10-16-18(30)26-21(31)24-16)11-22-29(17)20(27-19)23-15-8-9-15/h3-7,10-11,15H,2,8-9,12H2,1H3,(H,23,25,27)(H2,24,26,30,31)/b16-10- XTNPEQPJVCGGHV-YBEGLDIGSA-N 219616 US9303033, E31, Table 37A, Compound 290 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219616 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219616&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335659 329994795 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384106 FC(F)(F)C1CCCN(C1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H19F3N8O2/c19-18(20,21)10-2-1-5-28(8-10)15-25-13-9(6-12-14(30)26-17(31)24-12)7-22-29(13)16(27-15)23-11-3-4-11/h6-7,10-11H,1-5,8H2,(H,23,25,27)(H2,24,26,30,31)/b12-6- FRCZOAPHVIXPFO-SDQBBNPISA-N 219617 US9303033, F31, Table 37A, Compound 291 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219617&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335657 329994796 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384107 C[C@@H](N(C)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1 InChI=1S/C21H22N8O2/c1-12(13-6-4-3-5-7-13)28(2)19-25-17-14(10-16-18(30)26-21(31)24-16)11-22-29(17)20(27-19)23-15-8-9-15/h3-7,10-12,15H,8-9H2,1-2H3,(H,23,25,27)(H2,24,26,30,31)/b16-10-/t12-/m1/s1 LWJXQRYDKQWFLZ-YUSFRKCESA-N 219618 US9303033, G31, Table 37A, Compound 292 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219618 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219618&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335666 329994797 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384108 C[C@H](N(C)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1 InChI=1S/C21H22N8O2/c1-12(13-6-4-3-5-7-13)28(2)19-25-17-14(10-16-18(30)26-21(31)24-16)11-22-29(17)20(27-19)23-15-8-9-15/h3-7,10-12,15H,8-9H2,1-2H3,(H,23,25,27)(H2,24,26,30,31)/b16-10-/t12-/m0/s1 LWJXQRYDKQWFLZ-KPENOIPVSA-N 219619 US9303033, H31, Table 37A, Compound 293 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219619 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219619&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335863 329994798 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384109 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)N1CCc2ccccc2C1 InChI=1S/C21H20N8O2/c30-18-16(24-21(31)26-18)9-14-10-22-29-17(14)25-19(27-20(29)23-15-5-6-15)28-8-7-12-3-1-2-4-13(12)11-28/h1-4,9-10,15H,5-8,11H2,(H,23,25,27)(H2,24,26,30,31)/b16-9- CQNZFUTZIGAFRL-SXGWCWSVSA-N 219620 US9303033, I31, Table 37A, Compound 294 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219620 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219620&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335408 329994799 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384110 CN(Cc1ccccc1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H20N8O2/c1-27(11-12-5-3-2-4-6-12)18-24-16-13(9-15-17(29)25-20(30)23-15)10-21-28(16)19(26-18)22-14-7-8-14/h2-6,9-10,14H,7-8,11H2,1H3,(H,22,24,26)(H2,23,25,29,30)/b15-9- KPVPUPSEQKONDO-DHDCSXOGSA-N 219621 US9303033, J31, Table 37A, Compound 295 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219621 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219621&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336053 329994800 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384111 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)N1CCSCC1 InChI=1S/C16H18N8O2S/c25-13-11(19-16(26)21-13)7-9-8-17-24-12(9)20-14(23-3-5-27-6-4-23)22-15(24)18-10-1-2-10/h7-8,10H,1-6H2,(H,18,20,22)(H2,19,21,25,26)/b11-7- AHDJEQAVTOGMPF-XFFZJAGNSA-N 219622 US9303033, K31, Table 37A, Compound 296 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219622 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219622&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335655 329994801 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384112 CN(Cc1ccccc1Cl)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H19ClN8O2/c1-28(10-11-4-2-3-5-14(11)21)18-25-16-12(8-15-17(30)26-20(31)24-15)9-22-29(16)19(27-18)23-13-6-7-13/h2-5,8-9,13H,6-7,10H2,1H3,(H,23,25,27)(H2,24,26,30,31)/b15-8- FWQYWMIAOAIRFM-NVNXTCNLSA-N 219623 US9303033, L31, Table 37A, Compound 297 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219623 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219623&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313877 329994802 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384113 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCC3CCOCC3)nc12 InChI=1S/C18H22N8O3/c27-15-13(22-18(28)24-15)7-11-9-20-26-14(11)23-16(25-17(26)21-12-1-2-12)19-8-10-3-5-29-6-4-10/h7,9-10,12H,1-6,8H2,(H2,19,21,23,25)(H2,22,24,27,28)/b13-7- VNKSYNOCLKZDBW-QPEQYQDCSA-N 219624 US9303033, M31, Table 37A, Compound 298 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219624 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219624&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336063 329994803 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384114 CN(CCC#N)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C16H17N9O2/c1-24(6-2-5-17)14-21-12-9(7-11-13(26)22-16(27)20-11)8-18-25(12)15(23-14)19-10-3-4-10/h7-8,10H,2-4,6H2,1H3,(H,19,21,23)(H2,20,22,26,27)/b11-7- KNLMTMMPIVRAEN-XFFZJAGNSA-N 219625 US9303033, N31, Table 37A, Compound 299 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219625 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219625&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335663 329994804 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384115 FC(F)(F)C1CCCN1c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C17H17F3N8O2/c18-17(19,20)11-2-1-5-27(11)14-24-12-8(6-10-13(29)25-16(30)23-10)7-21-28(12)15(26-14)22-9-3-4-9/h6-7,9,11H,1-5H2,(H,22,24,26)(H2,23,25,29,30)/b10-6- NEGDFRGTLFROJZ-POHAHGRESA-N 219626 US9303033, O31, Table 37A, Compound 300 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219626 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219626&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335868 329994805 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384116 CS(=O)(=O)CCNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C15H18N8O4S/c1-28(26,27)5-4-16-13-20-11-8(6-10-12(24)21-15(25)19-10)7-17-23(11)14(22-13)18-9-2-3-9/h6-7,9H,2-5H2,1H3,(H2,16,18,20,22)(H2,19,21,24,25)/b10-6- NMRYWBNQHFPAHP-POHAHGRESA-N 219627 US9303033, P31, Table 37A, Compound 301 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219627 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219627&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335869 329994806 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384117 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)N1CCCC1c1cccnc1 InChI=1S/C21H21N9O2/c31-18-15(25-21(32)27-18)9-13-11-23-30-17(13)26-19(28-20(30)24-14-5-6-14)29-8-2-4-16(29)12-3-1-7-22-10-12/h1,3,7,9-11,14,16H,2,4-6,8H2,(H,24,26,28)(H2,25,27,31,32)/b15-9- ZGJIILUTKCTRRI-DHDCSXOGSA-N 219628 US9303033, Q31, Table 37A, Compound 302 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219628 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219628&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336156 329994807 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384118 CC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1cccc(C)n1 InChI=1S/C20H21N9O2/c1-10-4-3-5-14(22-10)11(2)23-18-26-16-12(8-15-17(30)27-20(31)25-15)9-21-29(16)19(28-18)24-13-6-7-13/h3-5,8-9,11,13H,6-7H2,1-2H3,(H2,23,24,26,28)(H2,25,27,30,31)/b15-8- SUBVKARHPPAQKT-NVNXTCNLSA-N 219629 US9303033, R31, Table 37A, Compound 303 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219629 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219629&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336131 329994808 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384119 CC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1cc(C)ccn1 InChI=1S/C20H21N9O2/c1-10-5-6-21-14(7-10)11(2)23-18-26-16-12(8-15-17(30)27-20(31)25-15)9-22-29(16)19(28-18)24-13-3-4-13/h5-9,11,13H,3-4H2,1-2H3,(H2,23,24,26,28)(H2,25,27,30,31)/b15-8- HJRXYYQPUPDVPH-NVNXTCNLSA-N 219630 US9303033, S31, Table 37A, Compound 304 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219630 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219630&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335405 329994809 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384120 CC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ncccc1C InChI=1S/C20H21N9O2/c1-10-4-3-7-21-15(10)11(2)23-18-26-16-12(8-14-17(30)27-20(31)25-14)9-22-29(16)19(28-18)24-13-5-6-13/h3-4,7-9,11,13H,5-6H2,1-2H3,(H2,23,24,26,28)(H2,25,27,30,31)/b14-8- WHOJDIGEVOKSRZ-ZSOIEALJSA-N 219631 US9303033, T31, Table 37A, Compound 305 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219631 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219631&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335667 329994810 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384121 CC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccc(C)cn1 InChI=1S/C20H21N9O2/c1-10-3-6-14(21-8-10)11(2)23-18-26-16-12(7-15-17(30)27-20(31)25-15)9-22-29(16)19(28-18)24-13-4-5-13/h3,6-9,11,13H,4-5H2,1-2H3,(H2,23,24,26,28)(H2,25,27,30,31)/b15-7- FFHKWYQJRPAXLG-CHHVJCJISA-N 219632 US9303033, U31, Table 37A, Compound 306 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219632 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219632&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335877 329994811 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384122 CCC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccn1 InChI=1S/C20H21N9O2/c1-2-13(14-5-3-4-8-21-14)24-18-26-16-11(9-15-17(30)27-20(31)25-15)10-22-29(16)19(28-18)23-12-6-7-12/h3-5,8-10,12-13H,2,6-7H2,1H3,(H2,23,24,26,28)(H2,25,27,30,31)/b15-9- HOUKSMSPSBOKKT-DHDCSXOGSA-N 219633 US9303033, V31, Table 37A, Compound 307 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219633 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219633&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335878 329994812 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384123 Cc1cccc(n1)C(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C1CC1 InChI=1S/C22H23N9O2/c1-11-3-2-4-15(24-11)17(12-5-6-12)27-20-28-18-13(9-16-19(32)29-22(33)26-16)10-23-31(18)21(30-20)25-14-7-8-14/h2-4,9-10,12,14,17H,5-8H2,1H3,(H2,25,27,28,30)(H2,26,29,32,33)/b16-9- HKADUNZSIGHJLP-SXGWCWSVSA-N 219634 US9303033, W31, Table 37A, Compound 308 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219634&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335210 329994813 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384124 C[C@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccn1 InChI=1S/C19H19N9O2/c1-10(13-4-2-3-7-20-13)22-17-25-15-11(8-14-16(29)26-19(30)24-14)9-21-28(15)18(27-17)23-12-5-6-12/h2-4,7-10,12H,5-6H2,1H3,(H2,22,23,25,27)(H2,24,26,29,30)/b14-8-/t10-/m0/s1 UATGVDJLQLGXHO-WULZRQGASA-N 219635 US9303033, X31, Table 37A, Compound 309 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219635 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219635&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335419 329994814 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384125 FC(F)(F)c1ccc(nc1)N1CCN(CC1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H21F3N10O2/c23-22(24,25)13-1-4-16(26-11-13)33-5-7-34(8-6-33)19-30-17-12(9-15-18(36)31-21(37)29-15)10-27-35(17)20(32-19)28-14-2-3-14/h1,4,9-11,14H,2-3,5-8H2,(H,28,30,32)(H2,29,31,36,37)/b15-9- CNCLDXLRXMRLMQ-DHDCSXOGSA-N 219636 US9303033, Y31, Table 37A, Compound 310 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219636&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336062 329994815 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384126 FC(F)(F)c1ccnc(c1)N1CCN(CC1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H21F3N10O2/c23-22(24,25)13-3-4-26-16(10-13)33-5-7-34(8-6-33)19-30-17-12(9-15-18(36)31-21(37)29-15)11-27-35(17)20(32-19)28-14-1-2-14/h3-4,9-11,14H,1-2,5-8H2,(H,28,30,32)(H2,29,31,36,37)/b15-9- NAPCJVNFRVAGFG-DHDCSXOGSA-N 219637 US9303033, Z31, Table 37A, Compound 311 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219637&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335653 329994816 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384127 FC(F)(F)c1cccnc1N1CCN(CC1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H21F3N10O2/c23-22(24,25)14-2-1-5-26-17(14)33-6-8-34(9-7-33)19-30-16-12(10-15-18(36)31-21(37)29-15)11-27-35(16)20(32-19)28-13-3-4-13/h1-2,5,10-11,13H,3-4,6-9H2,(H,28,30,32)(H2,29,31,36,37)/b15-10- ZSLFNQQKFPHIRU-GDNBJRDFSA-N 219638 US9303033, A32, Table 37A, Compound 312 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219638&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336168 329994817 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384128 FC(F)(F)c1cccc(n1)N1CCN(CC1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H21F3N10O2/c23-22(24,25)15-2-1-3-16(29-15)33-6-8-34(9-7-33)19-30-17-12(10-14-18(36)31-21(37)28-14)11-26-35(17)20(32-19)27-13-4-5-13/h1-3,10-11,13H,4-9H2,(H,27,30,32)(H2,28,31,36,37)/b14-10- UJOFHCKITHGCCU-UVTDQMKNSA-N 219639 US9303033, B32, Table 37A, Compound 313 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219639&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335671 329994818 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384129 NS(=O)(=O)c1ccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C19H19N9O4S/c20-33(31,32)13-5-1-10(2-6-13)8-21-17-25-15-11(7-14-16(29)26-19(30)24-14)9-22-28(15)18(27-17)23-12-3-4-12/h1-2,5-7,9,12H,3-4,8H2,(H2,20,31,32)(H2,21,23,25,27)(H2,24,26,29,30)/b14-7- UGIAYOGKPRTNHW-AUWJEWJLSA-N 219640 US9303033, C32, Table 37A, Compound 314 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219640 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219640&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 136483653 329994819 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384130 Fc1ccc(Cl)cc1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H16ClFN8O2/c20-11-1-4-13(21)9(5-11)7-22-17-26-15-10(6-14-16(30)27-19(31)25-14)8-23-29(15)18(28-17)24-12-2-3-12/h1,4-6,8,12H,2-3,7H2,(H2,22,24,26,28)(H2,25,27,30,31)/b14-6- ULHSIBYVELOKEQ-NSIKDUERSA-N 219641 US9303033, D32, Table 37A, Compound 315 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219641 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219641&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335414 329994820 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384131 CCN(Cc1ccncc1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H21N9O2/c1-2-28(11-12-5-7-21-8-6-12)18-25-16-13(9-15-17(30)26-20(31)24-15)10-22-29(16)19(27-18)23-14-3-4-14/h5-10,14H,2-4,11H2,1H3,(H,23,25,27)(H2,24,26,30,31)/b15-9- MTHFZQAFYGDVSD-DHDCSXOGSA-N 219642 US9303033, E32, Table 37A, Compound 316 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219642 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219642&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335670 329994821 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384132 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3cccc(c3)C#N)nc12 InChI=1S/C20H17N9O2/c21-8-11-2-1-3-12(6-11)9-22-18-26-16-13(7-15-17(30)27-20(31)25-15)10-23-29(16)19(28-18)24-14-4-5-14/h1-3,6-7,10,14H,4-5,9H2,(H2,22,24,26,28)(H2,25,27,30,31)/b15-7- BGPHEABYUFTWMP-CHHVJCJISA-N 219643 US9303033, F32, Table 37A, Compound 317 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219643&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336162 329994822 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384133 Fc1cccc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1Cl InChI=1S/C19H16ClFN8O2/c20-14-9(2-1-3-12(14)21)7-22-17-26-15-10(6-13-16(30)27-19(31)25-13)8-23-29(15)18(28-17)24-11-4-5-11/h1-3,6,8,11H,4-5,7H2,(H2,22,24,26,28)(H2,25,27,30,31)/b13-6- NAZPIYOSJOLXQT-MLPAPPSSSA-N 219644 US9303033, G32, Table 37A, Compound 318 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219644&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336064 329994823 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384134 Clc1cc(ccc1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C#N InChI=1S/C20H16ClN9O2/c21-14-5-10(7-22)1-2-11(14)8-23-18-27-16-12(6-15-17(31)28-20(32)26-15)9-24-30(16)19(29-18)25-13-3-4-13/h1-2,5-6,9,13H,3-4,8H2,(H2,23,25,27,29)(H2,26,28,31,32)/b15-6- IHBLLYWHYCJDBA-UUASQNMZSA-N 219645 US9303033, H32, Table 37A, Compound 319 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219645 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219645&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335870 329994824 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384135 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(Nc3ccc(cc3)-n3cccn3)nc12 InChI=1S/C21H18N10O2/c32-18-16(26-21(33)28-18)10-12-11-23-31-17(12)27-19(29-20(31)25-14-2-3-14)24-13-4-6-15(7-5-13)30-9-1-8-22-30/h1,4-11,14H,2-3H2,(H2,24,25,27,29)(H2,26,28,32,33)/b16-10- BVLIGOXBCFNEFX-YBEGLDIGSA-N 219646 US9303033, I32, Table 37A, Compound 320 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219646 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219646&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335880 329994825 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384136 CN1CCN(CC1)c1ccccc1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H28N10O2/c1-32-8-10-33(11-9-32)19-5-3-2-4-15(19)13-25-22-29-20-16(12-18-21(35)30-24(36)28-18)14-26-34(20)23(31-22)27-17-6-7-17/h2-5,12,14,17H,6-11,13H2,1H3,(H2,25,27,29,31)(H2,28,30,35,36)/b18-12- ASOVFWHPQGSMLQ-PDGQHHTCSA-N 219647 US9303033, J32, Table 37A, Compound 321 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219647 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219647&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336066 329994826 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384137 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3ccccc3N3CCCC3)nc12 InChI=1S/C23H25N9O2/c33-20-17(27-23(34)29-20)11-15-13-25-32-19(15)28-21(30-22(32)26-16-7-8-16)24-12-14-5-1-2-6-18(14)31-9-3-4-10-31/h1-2,5-6,11,13,16H,3-4,7-10,12H2,(H2,24,26,28,30)(H2,27,29,33,34)/b17-11- VWWRUYDCADFZOV-BOPFTXTBSA-N 219648 US9303033, K32, Table 37A, Compound 322 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219648 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219648&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335418 329994827 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384138 C[C@@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1cc(Cl)ccc1F InChI=1S/C20H18ClFN8O2/c1-9(13-7-11(21)2-5-14(13)22)24-18-27-16-10(6-15-17(31)28-20(32)26-15)8-23-30(16)19(29-18)25-12-3-4-12/h2,5-9,12H,3-4H2,1H3,(H2,24,25,27,29)(H2,26,28,31,32)/b15-6-/t9-/m1/s1 NWXMQVRONXOAAB-PHKJPBFMSA-N 219649 US9303033, L32, Table 37A, Compound 323 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219649 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219649&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336163 329994828 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384139 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3ccccc3-n3cccc3)nc12 InChI=1S/C23H21N9O2/c33-20-17(27-23(34)29-20)11-15-13-25-32-19(15)28-21(30-22(32)26-16-7-8-16)24-12-14-5-1-2-6-18(14)31-9-3-4-10-31/h1-6,9-11,13,16H,7-8,12H2,(H2,24,26,28,30)(H2,27,29,33,34)/b17-11- XXPZWUMLYPQEST-BOPFTXTBSA-N 219650 US9303033, M32, Table 37A, Compound 324 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219650 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219650&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335875 329994829 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384140 CN(Cc1cccnc1N1CCCC1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H26N10O2/c1-31(13-14-5-4-8-24-18(14)32-9-2-3-10-32)21-28-19-15(11-17-20(34)29-23(35)27-17)12-25-33(19)22(30-21)26-16-6-7-16/h4-5,8,11-12,16H,2-3,6-7,9-10,13H2,1H3,(H,26,28,30)(H2,27,29,34,35)/b17-11- BIRUUZAALQMLKH-BOPFTXTBSA-N 219651 US9303033, N32, Table 37A, Compound 325 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219651 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219651&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335874 329994830 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384141 CN(Cc1ccccc1N1CCCC1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H27N9O2/c1-31(14-15-6-2-3-7-19(15)32-10-4-5-11-32)22-28-20-16(12-18-21(34)29-24(35)27-18)13-25-33(20)23(30-22)26-17-8-9-17/h2-3,6-7,12-13,17H,4-5,8-11,14H2,1H3,(H,26,28,30)(H2,27,29,34,35)/b18-12- UJUIIWXUTVREKO-PDGQHHTCSA-N 219652 US9303033, O32, Table 37A, Compound 326 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219652 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219652&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336172 329994831 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384142 Fc1cc(Cl)cc(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C19H16ClFN8O2/c20-11-3-9(4-12(21)6-11)7-22-17-26-15-10(5-14-16(30)27-19(31)25-14)8-23-29(15)18(28-17)24-13-1-2-13/h3-6,8,13H,1-2,7H2,(H2,22,24,26,28)(H2,25,27,30,31)/b14-5- LXKKZZPMFXSOTD-RZNTYIFUSA-N 219653 US9303033, P32, Table 37A, Compound 327 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219653 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219653&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336067 329994832 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384143 Fc1ccc(Cl)c(CNc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C19H16ClFN8O2/c20-13-4-1-11(21)5-9(13)7-22-17-26-15-10(6-14-16(30)27-19(31)25-14)8-23-29(15)18(28-17)24-12-2-3-12/h1,4-6,8,12H,2-3,7H2,(H2,22,24,26,28)(H2,25,27,30,31)/b14-6- ROAAEOQZSHLOOP-NSIKDUERSA-N 219654 US9303033, Q32, Table 37A, Compound 328 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219654 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219654&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336174 329994833 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384144 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(Nc3ccc(cc3)C#N)nc12 InChI=1S/C19H15N9O2/c20-8-10-1-3-12(4-2-10)22-17-25-15-11(7-14-16(29)26-19(30)24-14)9-21-28(15)18(27-17)23-13-5-6-13/h1-4,7,9,13H,5-6H2,(H2,22,23,25,27)(H2,24,26,29,30)/b14-7- GNHOYIJLOXGFCX-AUWJEWJLSA-N 219655 US9303033, R32, Table 37A, Compound 329 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219655 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219655&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336060 329994834 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384145 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(Nc3cccc(c3)C#N)nc12 InChI=1S/C19H15N9O2/c20-8-10-2-1-3-13(6-10)22-17-25-15-11(7-14-16(29)26-19(30)24-14)9-21-28(15)18(27-17)23-12-4-5-12/h1-3,6-7,9,12H,4-5H2,(H2,22,23,25,27)(H2,24,26,29,30)/b14-7- AUEIVTBWDORHCK-AUWJEWJLSA-N 219656 US9303033, S32, Table 37A, Compound 330 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219656 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219656&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335224 329994835 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384146 Fc1cc(ccc1Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C#N InChI=1S/C19H14FN9O2/c20-12-5-9(7-21)1-4-13(12)24-17-26-15-10(6-14-16(30)27-19(31)25-14)8-22-29(15)18(28-17)23-11-2-3-11/h1,4-6,8,11H,2-3H2,(H2,23,24,26,28)(H2,25,27,30,31)/b14-6- LKTPIAWCBFVTOW-NSIKDUERSA-N 219657 US9303033, T32, Table 37A, Compound 331 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219657 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219657&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336072 329994836 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384147 CCC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccc(cc1)S(C)(=O)=O InChI=1S/C22H24N8O4S/c1-3-16(12-4-8-15(9-5-12)35(2,33)34)25-20-27-18-13(10-17-19(31)28-22(32)26-17)11-23-30(18)21(29-20)24-14-6-7-14/h4-5,8-11,14,16H,3,6-7H2,1-2H3,(H2,24,25,27,29)(H2,26,28,31,32)/b17-10- RNDIXSUKLDPIBL-YVLHZVERSA-N 219658 US9303033, U32, Table 37A, Compound 332 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219658 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219658&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335876 329994837 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384148 CCC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccc(C)cn1 InChI=1S/C21H23N9O2/c1-3-14(15-7-4-11(2)9-22-15)25-19-27-17-12(8-16-18(31)28-21(32)26-16)10-23-30(17)20(29-19)24-13-5-6-13/h4,7-10,13-14H,3,5-6H2,1-2H3,(H2,24,25,27,29)(H2,26,28,31,32)/b16-8- ZEILGIXAMITBLV-PXNMLYILSA-N 219659 US9303033, V32, Table 37A, Compound 333 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219659 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219659&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335879 329994838 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384149 CCC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1cccc(C)n1 InChI=1S/C21H23N9O2/c1-3-14(15-6-4-5-11(2)23-15)25-19-27-17-12(9-16-18(31)28-21(32)26-16)10-22-30(17)20(29-19)24-13-7-8-13/h4-6,9-10,13-14H,3,7-8H2,1-2H3,(H2,24,25,27,29)(H2,26,28,31,32)/b16-9- HPMUEZKCCCTLDR-SXGWCWSVSA-N 219660 US9303033, W32, Table 37A, Compound 334 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219660 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219660&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335242 329994839 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384150 CN(Cc1ccnc(C)c1)c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H21N9O2/c1-11-7-12(5-6-21-11)10-28(2)18-25-16-13(8-15-17(30)26-20(31)24-15)9-22-29(16)19(27-18)23-14-3-4-14/h5-9,14H,3-4,10H2,1-2H3,(H,23,25,27)(H2,24,26,30,31)/b15-8- GNZQVCDOPFCNMF-NVNXTCNLSA-N 219661 US9303033, X32, Table 37A, Compound 335 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219661 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219661&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335415 329994840 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384151 CCC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccncc1 InChI=1S/C20H21N9O2/c1-2-14(11-5-7-21-8-6-11)24-18-26-16-12(9-15-17(30)27-20(31)25-15)10-22-29(16)19(28-18)23-13-3-4-13/h5-10,13-14H,2-4H2,1H3,(H2,23,24,26,28)(H2,25,27,30,31)/b15-9- FKEMVPCXIFPYCO-DHDCSXOGSA-N 219662 US9303033, Y32, Table 37A, Compound 336 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219662 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219662&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336175 329994841 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384152 FC(F)(F)C(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccn1 InChI=1S/C19H16F3N9O2/c20-19(21,22)13(11-3-1-2-6-23-11)27-16-28-14-9(7-12-15(32)29-18(33)26-12)8-24-31(14)17(30-16)25-10-4-5-10/h1-3,6-8,10,13H,4-5H2,(H2,25,27,28,30)(H2,26,29,32,33)/b12-7- FPABDRUHPZXTFV-GHXNOFRVSA-N 219663 US9303033, Z32, Table 37A, Compound 337 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219663 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219663&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335262 329994842 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384153 CCCC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccncc1 InChI=1S/C21H23N9O2/c1-2-3-15(12-6-8-22-9-7-12)25-19-27-17-13(10-16-18(31)28-21(32)26-16)11-23-30(17)20(29-19)24-14-4-5-14/h6-11,14-15H,2-5H2,1H3,(H2,24,25,27,29)(H2,26,28,31,32)/b16-10- QAMYBIYHPTUDRU-YBEGLDIGSA-N 219664 US9303033, A33, Table 37A, Compound 338 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219664 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219664&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335881 329994843 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384154 Clc1ccc(Nc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)nc1 InChI=1S/C17H14ClN9O2/c18-9-1-4-12(19-7-9)23-15-24-13-8(5-11-14(28)25-17(29)22-11)6-20-27(13)16(26-15)21-10-2-3-10/h1,4-7,10H,2-3H2,(H2,22,25,28,29)(H2,19,21,23,24,26)/b11-5- QRHNRFUBGKYUQT-WZUFQYTHSA-N 219665 US9303033, B33, Table 37A, Compound 339 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219665 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219665&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336167 329994844 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384155 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(Nc3ccccc3C#N)nc12 InChI=1S/C19H15N9O2/c20-8-10-3-1-2-4-13(10)23-17-25-15-11(7-14-16(29)26-19(30)24-14)9-21-28(15)18(27-17)22-12-5-6-12/h1-4,7,9,12H,5-6H2,(H2,22,23,25,27)(H2,24,26,29,30)/b14-7- HMIGDTVZIJAZGL-AUWJEWJLSA-N 219666 US9303033, C33, Table 37A, Compound 340 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219666 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219666&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336056 329994845 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384156 CN1CCCN(CC1)c1ccccc1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C25H30N10O2/c1-33-9-4-10-34(12-11-33)20-6-3-2-5-16(20)14-26-23-30-21-17(13-19-22(36)31-25(37)29-19)15-27-35(21)24(32-23)28-18-7-8-18/h2-3,5-6,13,15,18H,4,7-12,14H2,1H3,(H2,26,28,30,32)(H2,29,31,36,37)/b19-13- QVEGAZHEARTEHY-UYRXBGFRSA-N 219667 US9303033, D33, Table 37A, Compound 341 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219667 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219667&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335227 329994846 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384157 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)N1CCc2ccccc12 InChI=1S/C20H18N8O2/c29-17-14(23-20(30)25-17)9-12-10-21-28-16(12)24-18(26-19(28)22-13-5-6-13)27-8-7-11-3-1-2-4-15(11)27/h1-4,9-10,13H,5-8H2,(H,22,24,26)(H2,23,25,29,30)/b14-9- VDWAERAJZQGZKR-ZROIWOOFSA-N 219668 US9303033, E33, Table 37A, Compound 342 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219668 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219668&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314298 329994847 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384158 C[C@@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccc(cc1F)C#N InChI=1S/C21H18FN9O2/c1-10(14-5-2-11(8-23)6-15(14)22)25-19-28-17-12(7-16-18(32)29-21(33)27-16)9-24-31(17)20(30-19)26-13-3-4-13/h2,5-7,9-10,13H,3-4H2,1H3,(H2,25,26,28,30)(H2,27,29,32,33)/b16-7-/t10-/m1/s1 WNFFOBCDONSCGD-SMUOPJFFSA-N 219669 US9303033, F33, Table 37A, Compound 343 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219669 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219669&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313806 329994848 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384159 C[C@@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1cc(C)ccc1F InChI=1S/C21H21FN8O2/c1-10-3-6-15(22)14(7-10)11(2)24-19-27-17-12(8-16-18(31)28-21(32)26-16)9-23-30(17)20(29-19)25-13-4-5-13/h3,6-9,11,13H,4-5H2,1-2H3,(H2,24,25,27,29)(H2,26,28,31,32)/b16-8-/t11-/m1/s1 UVZDSCQGOUIQTG-OUZNOSRWSA-N 219670 US9303033, G33, Table 37A, Compound 344 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219670 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219670&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314005 329994849 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384160 C[C@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1cc(Cl)ccc1F InChI=1S/C20H18ClFN8O2/c1-9(13-7-11(21)2-5-14(13)22)24-18-27-16-10(6-15-17(31)28-20(32)26-15)8-23-30(16)19(29-18)25-12-3-4-12/h2,5-9,12H,3-4H2,1H3,(H2,24,25,27,29)(H2,26,28,31,32)/b15-6-/t9-/m0/s1 NWXMQVRONXOAAB-JEHWNMSRSA-N 219671 US9303033, H33, Table 37A, Compound 345::US9303033, L49, Table 59A, Compound 22 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219671 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219671&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314716 329994850 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384161 Cc1nccn1-c1ccccc1CNc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H22N10O2/c1-13-24-8-9-32(13)18-5-3-2-4-14(18)11-25-21-29-19-15(10-17-20(34)30-23(35)28-17)12-26-33(19)22(31-21)27-16-6-7-16/h2-5,8-10,12,16H,6-7,11H2,1H3,(H2,25,27,29,31)(H2,28,30,34,35)/b17-10- BPXHLTAENPCZGP-YVLHZVERSA-N 219672 US9303033, I33, Table 37A, Compound 346 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219672 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219672&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314482 329994851 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384162 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3ccccc3-n3cccn3)nc12 InChI=1S/C22H20N10O2/c33-19-16(27-22(34)29-19)10-14-12-25-32-18(14)28-20(30-21(32)26-15-6-7-15)23-11-13-4-1-2-5-17(13)31-9-3-8-24-31/h1-5,8-10,12,15H,6-7,11H2,(H2,23,26,28,30)(H2,27,29,33,34)/b16-10- YNHNJXRVUXPYNA-YBEGLDIGSA-N 219673 US9303033, J33, Table 37A, Compound 347 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219673 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219673&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314021 329994852 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384163 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3ccccc3-n3cncn3)nc12 InChI=1S/C21H19N11O2/c33-18-15(27-21(34)29-18)7-13-9-24-32-17(13)28-19(30-20(32)26-14-5-6-14)23-8-12-3-1-2-4-16(12)31-11-22-10-25-31/h1-4,7,9-11,14H,5-6,8H2,(H2,23,26,28,30)(H2,27,29,33,34)/b15-7- HPTLSRIAYRXPJF-CHHVJCJISA-N 219674 US9303033, K33, Table 37A, Compound 348 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219674 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219674&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315020 329994853 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384164 CC(Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1-n1cccn1 InChI=1S/C23H22N10O2/c1-13(16-5-2-3-6-18(16)32-10-4-9-24-32)26-21-29-19-14(11-17-20(34)30-23(35)28-17)12-25-33(19)22(31-21)27-15-7-8-15/h2-6,9-13,15H,7-8H2,1H3,(H2,26,27,29,31)(H2,28,30,34,35)/b17-11- JMJOZJJSEFMDEK-BOPFTXTBSA-N 219675 US9303033, L33, Table 37A, Compound 349 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219675 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219675&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314524 329994854 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384165 Fc1ccc(Cl)c(Nc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C18H14ClFN8O2/c19-11-4-1-9(20)6-12(11)23-16-25-14-8(5-13-15(29)26-18(30)24-13)7-21-28(14)17(27-16)22-10-2-3-10/h1,4-7,10H,2-3H2,(H2,22,23,25,27)(H2,24,26,29,30)/b13-5- JNZSGOGLTIFCCH-ACAGNQJTSA-N 219676 US9303033, M33, Table 37A, Compound 350 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219676 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219676&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335248 329994855 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384166 Fc1ccc(Cl)cc1Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H14ClFN8O2/c19-9-1-4-11(20)12(6-9)23-16-25-14-8(5-13-15(29)26-18(30)24-13)7-21-28(14)17(27-16)22-10-2-3-10/h1,4-7,10H,2-3H2,(H2,22,23,25,27)(H2,24,26,29,30)/b13-5- SFTSJPGIBPFOCM-ACAGNQJTSA-N 219677 US9303033, N33, Table 37A, Compound 351 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219677 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219677&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335239 329994856 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384167 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3cccnc3N3CCOCC3)nc12 InChI=1S/C22H24N10O3/c33-19-16(27-22(34)29-19)10-14-12-25-32-18(14)28-20(30-21(32)26-15-3-4-15)24-11-13-2-1-5-23-17(13)31-6-8-35-9-7-31/h1-2,5,10,12,15H,3-4,6-9,11H2,(H2,24,26,28,30)(H2,27,29,33,34)/b16-10- UJEQDJNUXCFGDO-YBEGLDIGSA-N 219678 US9303033, O33, Table 37A, Compound 352 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219678 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219678&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335420 329994857 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384168 Fc1cc(Nc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc(c1)C#N InChI=1S/C19H14FN9O2/c20-11-3-9(7-21)4-13(6-11)23-17-26-15-10(5-14-16(30)27-19(31)25-14)8-22-29(15)18(28-17)24-12-1-2-12/h3-6,8,12H,1-2H2,(H2,23,24,26,28)(H2,25,27,30,31)/b14-5- KLGDQXFNJKPKKU-RZNTYIFUSA-N 219679 US9303033, P33, Table 37A, Compound 353 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219679 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219679&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335674 329994858 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384169 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NCc3ccccc3-c3ccccc3)nc12 InChI=1S/C25H22N8O2/c34-22-20(29-25(35)31-22)12-17-14-27-33-21(17)30-23(32-24(33)28-18-10-11-18)26-13-16-8-4-5-9-19(16)15-6-2-1-3-7-15/h1-9,12,14,18H,10-11,13H2,(H2,26,28,30,32)(H2,29,31,34,35)/b20-12- MLNYHFJSHFSRRH-NDENLUEZSA-N 219680 US9303033, Q33, Table 37A, Compound 354::US9303033, V48, Table 59A, Compound 6 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219680&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335375 329994859 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384170 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)-n1ccnc1 InChI=1S/C15H13N9O2/c25-12-10(19-15(26)21-12)5-8-6-17-24-11(8)20-13(23-4-3-16-7-23)22-14(24)18-9-1-2-9/h3-7,9H,1-2H2,(H,18,20,22)(H2,19,21,25,26)/b10-5- DHSVQYPPQPCZGC-YHYXMXQVSA-N 219681 US9303033, R33, Table 38A, Compound 1 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219681 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219681&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314129 329994860 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384171 CC1C=CC(C)N1c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H20N8O2/c1-9-3-4-10(2)25(9)16-22-14-11(7-13-15(27)23-18(28)21-13)8-19-26(14)17(24-16)20-12-5-6-12/h3-4,7-10,12H,5-6H2,1-2H3,(H,20,22,24)(H2,21,23,27,28)/b13-7- QHHKYXRZSGFCGV-QPEQYQDCSA-N 219682 US9303033, S33, Table 38A, Compound 2 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219682 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219682&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315159 329994861 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384172 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)-n1cnc2ccccc12 InChI=1S/C19H15N9O2/c29-16-13(23-19(30)25-16)7-10-8-21-28-15(10)24-17(26-18(28)22-11-5-6-11)27-9-20-12-3-1-2-4-14(12)27/h1-4,7-9,11H,5-6H2,(H,22,24,26)(H2,23,25,29,30)/b13-7- RESYXIXRSKESNQ-QPEQYQDCSA-N 219683 US9303033, T33, Table 38A, Compound 3 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219683&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315021 329994862 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384173 Cc1cc2ncn(-c3nc(NC4CC4)n4ncc(\C=C5/NC(=O)NC5=O)c4n3)c2cc1C InChI=1S/C21H19N9O2/c1-10-5-14-16(6-11(10)2)29(9-22-14)19-26-17-12(7-15-18(31)27-21(32)25-15)8-23-30(17)20(28-19)24-13-3-4-13/h5-9,13H,3-4H2,1-2H3,(H,24,26,28)(H2,25,27,31,32)/b15-7- QMVGBDLWVMGCJR-CHHVJCJISA-N 219684 US9303033, U33, Table 38A, Compound 4 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219684 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219684&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314293 329994863 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384174 Cc1nc2ccccc2n1-c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H17N9O2/c1-10-22-13-4-2-3-5-15(13)28(10)18-25-16-11(8-14-17(30)26-20(31)24-14)9-21-29(16)19(27-18)23-12-6-7-12/h2-5,8-9,12H,6-7H2,1H3,(H,23,25,27)(H2,24,26,30,31)/b14-8- YMEOKQGTHRYIOU-ZSOIEALJSA-N 219685 US9303033, V33, Table 38A, Compound 5 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219685 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219685&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313746 329994864 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384175 Cc1ccc2n(cnc2c1)-c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H17N9O2/c1-10-2-5-15-13(6-10)21-9-28(15)18-25-16-11(7-14-17(30)26-20(31)24-14)8-22-29(16)19(27-18)23-12-3-4-12/h2,5-9,12H,3-4H2,1H3,(H,23,25,27)(H2,24,26,30,31)/b14-7- DYZGSNSDLYGJHE-AUWJEWJLSA-N 219686 US9303033, W33, Table 38A, Compound 6 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219686&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313897 329994865 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384176 Cc1nccn1-c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C16H15N9O2/c1-8-17-4-5-24(8)14-21-12-9(6-11-13(26)22-16(27)20-11)7-18-25(12)15(23-14)19-10-2-3-10/h4-7,10H,2-3H2,1H3,(H,19,21,23)(H2,20,22,26,27)/b11-6- NTVDNYBYZNZSOL-WDZFZDKYSA-N 219687 US9303033, X33, Table 38A, Compound 7 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219687 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219687&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314826 329994866 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384177 CCN1CCN(CC1)C(=O)c1ccc2n(cnc2c1)-c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C26H27N11O3/c1-2-34-7-9-35(10-8-34)23(39)15-3-6-20-18(11-15)27-14-36(20)24-31-21-16(12-19-22(38)32-26(40)30-19)13-28-37(21)25(33-24)29-17-4-5-17/h3,6,11-14,17H,2,4-5,7-10H2,1H3,(H,29,31,33)(H2,30,32,38,40)/b19-12- AKHUMDMOKAZSJM-UNOMPAQXSA-N 219688 US9303033, Y33, Table 38A, Compound 8 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219688 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219688&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313833 329994867 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384178 O=C(NCCCN1CCCC1)c1ccc2n(cnc2c1)-c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C27H29N11O3/c39-23(28-8-3-11-36-9-1-2-10-36)16-4-7-21-19(12-16)29-15-37(21)25-33-22-17(13-20-24(40)34-27(41)32-20)14-30-38(22)26(35-25)31-18-5-6-18/h4,7,12-15,18H,1-3,5-6,8-11H2,(H,28,39)(H,31,33,35)(H2,32,34,40,41)/b20-13- KYRUYDIKOZJSQG-MOSHPQCFSA-N 219689 US9303033, Z33, Table 38A, Compound 9 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219689 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219689&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314177 329994868 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384179 CN(C)C1CCN(C1)C(=O)c1ccc2n(cnc2c1)-c1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C26H27N11O3/c1-34(2)17-7-8-35(12-17)23(39)14-3-6-20-18(9-14)27-13-36(20)24-31-21-15(10-19-22(38)32-26(40)30-19)11-28-37(21)25(33-24)29-16-4-5-16/h3,6,9-11,13,16-17H,4-5,7-8,12H2,1-2H3,(H,29,31,33)(H2,30,32,38,40)/b19-10- HUXLUYCNBAYIGN-GRSHGNNSSA-N 219690 US9303033, A34, Table 38A, Compound 10 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219690 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219690&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314773 329994869 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384180 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)-n1cnc(CN2CCCC2)c1 InChI=1S/C20H22N10O2/c31-17-15(24-20(32)26-17)7-12-8-22-30-16(12)25-18(27-19(30)23-13-3-4-13)29-10-14(21-11-29)9-28-5-1-2-6-28/h7-8,10-11,13H,1-6,9H2,(H,23,25,27)(H2,24,26,31,32)/b15-7- BHPXRWBGKASCGE-CHHVJCJISA-N 219691 US9303033, B34, Table 38A, Compound 11 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219691 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219691&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314252 329994870 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384181 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(nc12)-n1cnc(CN2CCOCC2)c1 InChI=1S/C20H22N10O3/c31-17-15(24-20(32)26-17)7-12-8-22-30-16(12)25-18(27-19(30)23-13-1-2-13)29-10-14(21-11-29)9-28-3-5-33-6-4-28/h7-8,10-11,13H,1-6,9H2,(H,23,25,27)(H2,24,26,31,32)/b15-7- GNIMMCZJAMHZFB-CHHVJCJISA-N 219692 US9303033, C34, Table 38A, Compound 12 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219692 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219692&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315046 329994871 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384182 CN1CCN(Cc2cn(cn2)-c2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)CC1 InChI=1S/C21H25N11O2/c1-29-4-6-30(7-5-29)10-15-11-31(12-22-15)19-26-17-13(8-16-18(33)27-21(34)25-16)9-23-32(17)20(28-19)24-14-2-3-14/h8-9,11-12,14H,2-7,10H2,1H3,(H,24,26,28)(H2,25,27,33,34)/b16-8- ATHVIOMSBOMOFD-PXNMLYILSA-N 219693 US9303033, D34, Table 38A, Compound 13 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219693&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315089 329994872 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384183 Clc1cccc(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C18H14ClN7O3/c19-10-2-1-3-12(7-10)29-18-23-14-9(6-13-15(27)24-17(28)22-13)8-20-26(14)16(25-18)21-11-4-5-11/h1-3,6-8,11H,4-5H2,(H,21,23,25)(H2,22,24,27,28)/b13-6- RPCMXNFXSNSLCR-MLPAPPSSSA-N 219264 US9303033, E34, Table 39A, Compound 1::US9303033, I17, Table 33A, Compound 80 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219264 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219264&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67254434 329994443 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384184 Fc1ccc(Cl)cc1Oc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H13ClFN7O3/c19-9-1-4-11(20)13(6-9)30-18-24-14-8(5-12-15(28)25-17(29)23-12)7-21-27(14)16(26-18)22-10-2-3-10/h1,4-7,10H,2-3H2,(H,22,24,26)(H2,23,25,28,29)/b12-5- YTJDIBHUZDZUQW-XGICHPGQSA-N 219695 US9303033, F34, Table 39A, Compound 2 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219695 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219695&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335865 329994873 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384185 Fc1cccc(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C18H14FN7O3/c19-10-2-1-3-12(7-10)29-18-23-14-9(6-13-15(27)24-17(28)22-13)8-20-26(14)16(25-18)21-11-4-5-11/h1-3,6-8,11H,4-5H2,(H,21,23,25)(H2,22,24,27,28)/b13-6- ZGQGFPWEKAYONQ-MLPAPPSSSA-N 219696 US9303033, G34, Table 39A, Compound 3 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219696 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219696&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335427 329994874 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384186 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(Oc3ccc(cc3)-n3ccnc3)nc12 InChI=1S/C21H17N9O3/c31-18-16(25-20(32)27-18)9-12-10-23-30-17(12)26-21(28-19(30)24-13-1-2-13)33-15-5-3-14(4-6-15)29-8-7-22-11-29/h3-11,13H,1-2H2,(H,24,26,28)(H2,25,27,31,32)/b16-9- ZECZURPTNGMDLA-SXGWCWSVSA-N 219697 US9303033, H34, Table 39A, Compound 4 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219697 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219697&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335672 329994875 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384187 CC(=O)c1ccc(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C20H17N7O4/c1-10(28)11-2-6-14(7-3-11)31-20-24-16-12(8-15-17(29)25-19(30)23-15)9-21-27(16)18(26-20)22-13-4-5-13/h2-3,6-9,13H,4-5H2,1H3,(H,22,24,26)(H2,23,25,29,30)/b15-8- IFFLBQJYYNZSCX-NVNXTCNLSA-N 219698 US9303033, I34, Table 39A, Compound 5 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219698&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335677 329994876 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384188 FC(F)(F)Oc1cccc(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C19H14F3N7O4/c20-19(21,22)33-12-3-1-2-11(7-12)32-18-26-14-9(6-13-15(30)27-17(31)25-13)8-23-29(14)16(28-18)24-10-4-5-10/h1-3,6-8,10H,4-5H2,(H,24,26,28)(H2,25,27,30,31)/b13-6- OBFZJXPRFJWSIV-MLPAPPSSSA-N 219699 US9303033, J34, Table 39A, Compound 6 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219699 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219699&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335680 329994877 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384189 Fc1ccc(cc1Oc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C(F)(F)F InChI=1S/C19H13F4N7O3/c20-11-4-1-9(19(21,22)23)6-13(11)33-18-27-14-8(5-12-15(31)28-17(32)26-12)7-24-30(14)16(29-18)25-10-2-3-10/h1,4-7,10H,2-3H2,(H,25,27,29)(H2,26,28,31,32)/b12-5- ZPFYYUWASBRBTG-XGICHPGQSA-N 219700 US9303033, K34, Table 39A, Compound 7 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219700 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219700&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335426 329994878 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384190 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(Oc3ccc(cc3)-n3cccc3)nc12 InChI=1S/C22H18N8O3/c31-19-17(25-21(32)27-19)11-13-12-23-30-18(13)26-22(28-20(30)24-14-3-4-14)33-16-7-5-15(6-8-16)29-9-1-2-10-29/h1-2,5-12,14H,3-4H2,(H,24,26,28)(H2,25,27,31,32)/b17-11- UOUQKTTWFUIWLJ-BOPFTXTBSA-N 219701 US9303033, L34, Table 39A, Compound 8 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219701 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219701&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335285 329994879 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384191 COc1ccc(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C19H17N7O4/c1-29-12-4-6-13(7-5-12)30-19-23-15-10(8-14-16(27)24-18(28)22-14)9-20-26(15)17(25-19)21-11-2-3-11/h4-9,11H,2-3H2,1H3,(H,21,23,25)(H2,22,24,27,28)/b14-8- SNAHDSVCSNLNOF-ZSOIEALJSA-N 219702 US9303033, M34, Table 39A, Compound 9 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219702&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335430 329994880 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384192 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(Oc3cccc(c3)C3=NCCN3)nc12 InChI=1S/C21H19N9O3/c31-18-15(26-20(32)28-18)9-12-10-24-30-17(12)27-21(29-19(30)25-13-4-5-13)33-14-3-1-2-11(8-14)16-22-6-7-23-16/h1-3,8-10,13H,4-7H2,(H,22,23)(H,25,27,29)(H2,26,28,31,32)/b15-9- KHVGKVUAKPLPDY-DHDCSXOGSA-N 219703 US9303033, N34, Table 39A, Compound 10 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219703 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219703&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336087 329994881 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384193 Fc1cccc(Cl)c1Oc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H13ClFN7O3/c19-10-2-1-3-11(20)13(10)30-18-24-14-8(6-12-15(28)25-17(29)23-12)7-21-27(14)16(26-18)22-9-4-5-9/h1-3,6-7,9H,4-5H2,(H,22,24,26)(H2,23,25,28,29)/b12-6- ZFRQOPBWPPIOFN-SDQBBNPISA-N 219704 US9303033, O34, Table 39A, Compound 11 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219704 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219704&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335883 329994882 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384194 Cc1ccc(F)c(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C19H16FN7O3/c1-9-2-5-12(20)14(6-9)30-19-24-15-10(7-13-16(28)25-18(29)23-13)8-21-27(15)17(26-19)22-11-3-4-11/h2,5-8,11H,3-4H2,1H3,(H,22,24,26)(H2,23,25,28,29)/b13-7- YZGVHRDHSDDULB-QPEQYQDCSA-N 219705 US9303033, P34, Table 39A, Compound 12 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219705 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219705&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335887 329994883 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384195 COc1ccc(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c(Cl)c1 InChI=1S/C19H16ClN7O4/c1-30-11-4-5-14(12(20)7-11)31-19-24-15-9(6-13-16(28)25-18(29)23-13)8-21-27(15)17(26-19)22-10-2-3-10/h4-8,10H,2-3H2,1H3,(H,22,24,26)(H2,23,25,28,29)/b13-6- YOFHASCWNYTTSX-MLPAPPSSSA-N 219706 US9303033, Q34, Table 39A, Compound 13 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219706 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219706&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336186 329994884 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384196 FC(F)(F)c1ccc(Cl)c(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C19H13ClF3N7O3/c20-11-4-1-9(19(21,22)23)6-13(11)33-18-27-14-8(5-12-15(31)28-17(32)26-12)7-24-30(14)16(29-18)25-10-2-3-10/h1,4-7,10H,2-3H2,(H,25,27,29)(H2,26,28,31,32)/b12-5- QXXKJSPPIFXZLA-XGICHPGQSA-N 219707 US9303033, R34, Table 39A, Compound 14 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219707 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219707&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336199 329994885 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384197 OCc1ccc(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C19H17N7O4/c27-9-10-1-5-13(6-2-10)30-19-23-15-11(7-14-16(28)24-18(29)22-14)8-20-26(15)17(25-19)21-12-3-4-12/h1-2,5-8,12,27H,3-4,9H2,(H,21,23,25)(H2,22,24,28,29)/b14-7- SWNPFVNAYGLHFY-AUWJEWJLSA-N 219708 US9303033, S34, Table 39A, Compound 15 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219708 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219708&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335888 329994886 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384198 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(Oc3ccc4ncccc4c3)nc12 InChI=1S/C21H16N8O3/c30-18-16(25-20(31)27-18)9-12-10-23-29-17(12)26-21(28-19(29)24-13-3-4-13)32-14-5-6-15-11(8-14)2-1-7-22-15/h1-2,5-10,13H,3-4H2,(H,24,26,28)(H2,25,27,30,31)/b16-9- HDFACXPYUYZYJX-SXGWCWSVSA-N 219709 US9303033, T34, Table 39A, Compound 16 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219709 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219709&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335272 329994887 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384199 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(Oc3ccc4NC(=O)CCc4c3)nc12 InChI=1S/C21H18N8O4/c30-16-6-1-10-7-13(4-5-14(10)24-16)33-21-26-17-11(8-15-18(31)27-20(32)25-15)9-22-29(17)19(28-21)23-12-2-3-12/h4-5,7-9,12H,1-3,6H2,(H,24,30)(H,23,26,28)(H2,25,27,31,32)/b15-8- DRHMCVOECAEJBY-NVNXTCNLSA-N 219710 US9303033, U34, Table 39A, Compound 17 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219710 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219710&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336185 329994888 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384200 Fc1cc(Cl)ccc1Oc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H13ClFN7O3/c19-9-1-4-13(11(20)6-9)30-18-24-14-8(5-12-15(28)25-17(29)23-12)7-21-27(14)16(26-18)22-10-2-3-10/h1,4-7,10H,2-3H2,(H,22,24,26)(H2,23,25,28,29)/b12-5- PIJWCTWOUBGLEF-XGICHPGQSA-N 219711 US9303033, V34, Table 39A, Compound 18 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219711 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219711&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336083 329994889 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384201 CC(=O)c1cccc(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C20H17N7O4/c1-10(28)11-3-2-4-14(7-11)31-20-24-16-12(8-15-17(29)25-19(30)23-15)9-21-27(16)18(26-20)22-13-5-6-13/h2-4,7-9,13H,5-6H2,1H3,(H,22,24,26)(H2,23,25,29,30)/b15-8- IBLVMOFNCXJHDR-NVNXTCNLSA-N 219712 US9303033, W34, Table 39A, Compound 19 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219712 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219712&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336182 329994890 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384202 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(Oc3ccc4[nH]ccc4c3)nc12 InChI=1S/C20H16N8O3/c29-17-15(24-19(30)26-17)8-11-9-22-28-16(11)25-20(27-18(28)23-12-1-2-12)31-13-3-4-14-10(7-13)5-6-21-14/h3-9,12,21H,1-2H2,(H,23,25,27)(H2,24,26,29,30)/b15-8- GLTVDFQETVKIQE-NVNXTCNLSA-N 219713 US9303033, X34, Table 39A, Compound 20 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219713 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219713&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336190 329994891 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384203 Clc1cc(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)ccc1C#N InChI=1S/C19H13ClN8O3/c20-13-6-12(4-1-9(13)7-21)31-19-25-15-10(5-14-16(29)26-18(30)24-14)8-22-28(15)17(27-19)23-11-2-3-11/h1,4-6,8,11H,2-3H2,(H,23,25,27)(H2,24,26,29,30)/b14-5- USNMSERHEMNZGZ-RZNTYIFUSA-N 219714 US9303033, Y34, Table 39A, Compound 21 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219714 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219714&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336184 329994892 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384204 NC(=O)c1ccc(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C19H16N8O4/c20-14(28)9-1-5-12(6-2-9)31-19-24-15-10(7-13-16(29)25-18(30)23-13)8-21-27(15)17(26-19)22-11-3-4-11/h1-2,5-8,11H,3-4H2,(H2,20,28)(H,22,24,26)(H2,23,25,29,30)/b13-7- BXFOLEBIBFPICA-QPEQYQDCSA-N 219715 US9303033, Z34, Table 39A, Compound 22 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219715 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219715&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335261 329994893 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384205 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(Oc3cccc(c3)C#C)nc12 InChI=1S/C20H15N7O3/c1-2-11-4-3-5-14(8-11)30-20-24-16-12(9-15-17(28)25-19(29)23-15)10-21-27(16)18(26-20)22-13-6-7-13/h1,3-5,8-10,13H,6-7H2,(H,22,24,26)(H2,23,25,28,29)/b15-9- QFIDXJROTWJUOP-DHDCSXOGSA-N 219716 US9303033, A35, Table 39A, Compound 23 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219716 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219716&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 88941282 329994894 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384206 Clc1ccccc1Oc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H14ClN7O3/c19-11-3-1-2-4-13(11)29-18-23-14-9(7-12-15(27)24-17(28)22-12)8-20-26(14)16(25-18)21-10-5-6-10/h1-4,7-8,10H,5-6H2,(H,21,23,25)(H2,22,24,27,28)/b12-7- BNHDLABJCAACKV-GHXNOFRVSA-N 219717 US9303033, B35, Table 39A, Compound 24 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219717 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219717&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335684 329994895 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384207 Clc1ccc(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1Cl InChI=1S/C18H13Cl2N7O3/c19-11-4-3-10(6-12(11)20)30-18-24-14-8(5-13-15(28)25-17(29)23-13)7-21-27(14)16(26-18)22-9-1-2-9/h3-7,9H,1-2H2,(H,22,24,26)(H2,23,25,28,29)/b13-5- JYXQZGFFDFWCEO-ACAGNQJTSA-N 219718 US9303033, C35, Table 39A, Compound 25 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219718 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219718&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336078 329994896 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384208 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(Oc3cccc4[nH]nnc34)nc12 InChI=1S/C18H14N10O3/c29-15-11(21-17(30)23-15)6-8-7-19-28-14(8)22-18(24-16(28)20-9-4-5-9)31-12-3-1-2-10-13(12)26-27-25-10/h1-3,6-7,9H,4-5H2,(H,20,22,24)(H,25,26,27)(H2,21,23,29,30)/b11-6- GZLDHEFXAIUSKZ-WDZFZDKYSA-N 219719 US9303033, D35, Table 39A, Compound 26 Casein kinase II subunit beta >500 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219719 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219719&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335431 329994897 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384209 Brc1ccc(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c(c1)C#N InChI=1S/C19H13BrN8O3/c20-11-1-4-14(9(5-11)7-21)31-19-25-15-10(6-13-16(29)26-18(30)24-13)8-22-28(15)17(27-19)23-12-2-3-12/h1,4-6,8,12H,2-3H2,(H,23,25,27)(H2,24,26,29,30)/b13-6- BFWWPFPQUKEHPI-MLPAPPSSSA-N 219720 US9303033, E35, Table 39A, Compound 27 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219720 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219720&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335266 329994898 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384210 Fc1ccc(F)c(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C18H13F2N7O3/c19-9-1-4-11(20)13(6-9)30-18-24-14-8(5-12-15(28)25-17(29)23-12)7-21-27(14)16(26-18)22-10-2-3-10/h1,4-7,10H,2-3H2,(H,22,24,26)(H2,23,25,28,29)/b12-5- LURXTRZHSPJNSJ-XGICHPGQSA-N 219721 US9303033, F35, Table 39A, Compound 28 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219721 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219721&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335682 329994899 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384211 Brc1cc(ccc1Oc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C#N InChI=1S/C19H13BrN8O3/c20-12-5-9(7-21)1-4-14(12)31-19-25-15-10(6-13-16(29)26-18(30)24-13)8-22-28(15)17(27-19)23-11-2-3-11/h1,4-6,8,11H,2-3H2,(H,23,25,27)(H2,24,26,29,30)/b13-6- MRIJGJMLVJCPAR-MLPAPPSSSA-N 219722 US9303033, G35, Table 39A, Compound 29 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219722 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219722&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335882 329994900 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384212 COc1ccccc1Oc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H17N7O4/c1-29-13-4-2-3-5-14(13)30-19-23-15-10(8-12-16(27)24-18(28)22-12)9-20-26(15)17(25-19)21-11-6-7-11/h2-5,8-9,11H,6-7H2,1H3,(H,21,23,25)(H2,22,24,27,28)/b12-8- SPWOYXDFAQZQLT-WQLSENKSSA-N 219723 US9303033, H35, Table 39A, Compound 30 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219723 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219723&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335422 329994901 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384213 Cc1cc(F)ccc1Oc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H16FN7O3/c1-9-6-11(20)2-5-14(9)30-19-24-15-10(7-13-16(28)25-18(29)23-13)8-21-27(15)17(26-19)22-12-3-4-12/h2,5-8,12H,3-4H2,1H3,(H,22,24,26)(H2,23,25,28,29)/b13-7- XACXNKIPHUINEE-QPEQYQDCSA-N 219724 US9303033, I35, Table 39A, Compound 31 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219724 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219724&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336187 329994902 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384214 OCc1cccc(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C19H17N7O4/c27-9-10-2-1-3-13(6-10)30-19-23-15-11(7-14-16(28)24-18(29)22-14)8-20-26(15)17(25-19)21-12-4-5-12/h1-3,6-8,12,27H,4-5,9H2,(H,21,23,25)(H2,22,24,28,29)/b14-7- MWYJUQFXTWUHHX-AUWJEWJLSA-N 219725 US9303033, J35, Table 39A, Compound 32 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219725 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219725&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335669 329994903 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384215 COc1cc(Cl)ccc1Oc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H16ClN7O4/c1-30-14-7-10(20)2-5-13(14)31-19-24-15-9(6-12-16(28)25-18(29)23-12)8-21-27(15)17(26-19)22-11-3-4-11/h2,5-8,11H,3-4H2,1H3,(H,22,24,26)(H2,23,25,28,29)/b12-6- GQRXFEBCKFMREU-SDQBBNPISA-N 219726 US9303033, K35, Table 39A, Compound 33 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219726 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219726&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335885 329994904 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384216 Fc1cc(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)ccc1Cl InChI=1S/C18H13ClFN7O3/c19-11-4-3-10(6-12(11)20)30-18-24-14-8(5-13-15(28)25-17(29)23-13)7-21-27(14)16(26-18)22-9-1-2-9/h3-7,9H,1-2H2,(H,22,24,26)(H2,23,25,28,29)/b13-5- ORHAMZIZNNNXMA-ACAGNQJTSA-N 219727 US9303033, L35, Table 39A, Compound 34 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219727 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219727&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336200 329994905 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384217 Fc1ccc(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c(F)c1 InChI=1S/C18H13F2N7O3/c19-9-1-4-13(11(20)6-9)30-18-24-14-8(5-12-15(28)25-17(29)23-12)7-21-27(14)16(26-18)22-10-2-3-10/h1,4-7,10H,2-3H2,(H,22,24,26)(H2,23,25,28,29)/b12-5- AUIWHQUEMMVALX-XGICHPGQSA-N 219728 US9303033, M35, Table 39A, Compound 35 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219728 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219728&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336079 329994906 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384218 Fc1ccccc1Oc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H14FN7O3/c19-11-3-1-2-4-13(11)29-18-23-14-9(7-12-15(27)24-17(28)22-12)8-20-26(14)16(25-18)21-10-5-6-10/h1-4,7-8,10H,5-6H2,(H,21,23,25)(H2,22,24,27,28)/b12-7- BDLPWYRVBPVGID-GHXNOFRVSA-N 219729 US9303033, N35, Table 39A, Compound 36 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219729 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219729&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335269 329994907 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384219 COc1cc(ccc1Oc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C#N InChI=1S/C20H16N8O4/c1-31-15-6-10(8-21)2-5-14(15)32-20-25-16-11(7-13-17(29)26-19(30)24-13)9-22-28(16)18(27-20)23-12-3-4-12/h2,5-7,9,12H,3-4H2,1H3,(H,23,25,27)(H2,24,26,29,30)/b13-7- UAPSSWSQDAPNBA-QPEQYQDCSA-N 219730 US9303033, O35, Table 39A, Compound 37 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219730 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219730&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336082 329994908 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384220 Clc1cccc(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1Cl InChI=1S/C18H13Cl2N7O3/c19-10-2-1-3-12(13(10)20)30-18-24-14-8(6-11-15(28)25-17(29)23-11)7-21-27(14)16(26-18)22-9-4-5-9/h1-3,6-7,9H,4-5H2,(H,22,24,26)(H2,23,25,28,29)/b11-6- CNCMUUUITFRANP-WDZFZDKYSA-N 219731 US9303033, P35, Table 39A, Compound 38 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219731 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219731&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335685 329994909 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384221 Clc1cc(Cl)cc(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C18H13Cl2N7O3/c19-9-4-10(20)6-12(5-9)30-18-24-14-8(3-13-15(28)25-17(29)23-13)7-21-27(14)16(26-18)22-11-1-2-11/h3-7,11H,1-2H2,(H,22,24,26)(H2,23,25,28,29)/b13-3- RKPCQCTYWPQCOZ-DXNYSGJVSA-N 219732 US9303033, Q35, Table 39A, Compound 39 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219732 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219732&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336191 329994910 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384222 Clc1ccc(Cl)c(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C18H13Cl2N7O3/c19-9-1-4-11(20)13(6-9)30-18-24-14-8(5-12-15(28)25-17(29)23-12)7-21-27(14)16(26-18)22-10-2-3-10/h1,4-7,10H,2-3H2,(H,22,24,26)(H2,23,25,28,29)/b12-5- AEHJYZPZRGVULC-XGICHPGQSA-N 219733 US9303033, R35, Table 39A, Compound 40 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219733 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219733&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336193 329994911 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384223 Clc1ccc(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C18H14ClN7O3/c19-10-1-5-12(6-2-10)29-18-23-14-9(7-13-15(27)24-17(28)22-13)8-20-26(14)16(25-18)21-11-3-4-11/h1-2,5-8,11H,3-4H2,(H,21,23,25)(H2,22,24,27,28)/b13-7- HJDQUVIWOMPQEC-QPEQYQDCSA-N 219734 US9303033, S35, Table 39A, Compound 41 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219734&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335264 329994912 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384224 FC(F)(F)Oc1ccc(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C19H14F3N7O4/c20-19(21,22)33-12-5-3-11(4-6-12)32-18-26-14-9(7-13-15(30)27-17(31)25-13)8-23-29(14)16(28-18)24-10-1-2-10/h3-8,10H,1-2H2,(H,24,26,28)(H2,25,27,30,31)/b13-7- KLBPUIKUUWDVPN-QPEQYQDCSA-N 219735 US9303033, T35, Table 39A, Compound 42 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219735&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335259 329994913 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384225 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(Oc3ccccc3C#N)nc12 InChI=1S/C19H14N8O3/c20-8-10-3-1-2-4-14(10)30-19-24-15-11(7-13-16(28)25-18(29)23-13)9-21-27(15)17(26-19)22-12-5-6-12/h1-4,7,9,12H,5-6H2,(H,22,24,26)(H2,23,25,28,29)/b13-7- AIRXRZYITJXLES-QPEQYQDCSA-N 219736 US9303033, U35, Table 39A, Compound 43 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219736 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219736&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335884 329994914 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384226 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(Oc3cccc(c3)C#N)nc12 InChI=1S/C19H14N8O3/c20-8-10-2-1-3-13(6-10)30-19-24-15-11(7-14-16(28)25-18(29)23-14)9-21-27(15)17(26-19)22-12-4-5-12/h1-3,6-7,9,12H,4-5H2,(H,22,24,26)(H2,23,25,28,29)/b14-7- CDTMGXYIUQUDSU-AUWJEWJLSA-N 219737 US9303033, V35, Table 39A, Compound 44 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219737&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335253 329994915 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384227 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(Oc3ccc(cc3)C#N)nc12 InChI=1S/C19H14N8O3/c20-8-10-1-5-13(6-2-10)30-19-24-15-11(7-14-16(28)25-18(29)23-14)9-21-27(15)17(26-19)22-12-3-4-12/h1-2,5-7,9,12H,3-4H2,(H,22,24,26)(H2,23,25,28,29)/b14-7- HLVNUXTUHRAJHK-AUWJEWJLSA-N 219738 US9303033, W35, Table 39A, Compound 45 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219738 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219738&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335673 329994916 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384228 COc1cccc(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C19H17N7O4/c1-29-12-3-2-4-13(8-12)30-19-23-15-10(7-14-16(27)24-18(28)22-14)9-20-26(15)17(25-19)21-11-5-6-11/h2-4,7-9,11H,5-6H2,1H3,(H,21,23,25)(H2,22,24,27,28)/b14-7- TUVFAYFWWNKLGO-AUWJEWJLSA-N 219739 US9303033, X35, Table 39A, Compound 46 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219739 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219739&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335691 329994917 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384229 COc1cc(C)ccc1Oc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H19N7O4/c1-10-3-6-14(15(7-10)30-2)31-20-24-16-11(8-13-17(28)25-19(29)23-13)9-21-27(16)18(26-20)22-12-4-5-12/h3,6-9,12H,4-5H2,1-2H3,(H,22,24,26)(H2,23,25,28,29)/b13-8- MYLXPWQZDJGWKY-JYRVWZFOSA-N 219740 US9303033, Y35, Table 39A, Compound 47 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219740 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219740&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335890 329994918 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384230 COc1cc(ccc1Oc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C(C)O InChI=1S/C21H21N7O5/c1-10(29)11-3-6-15(16(8-11)32-2)33-21-25-17-12(7-14-18(30)26-20(31)24-14)9-22-28(17)19(27-21)23-13-4-5-13/h3,6-10,13,29H,4-5H2,1-2H3,(H,23,25,27)(H2,24,26,30,31)/b14-7- YVBORAIKRUEOME-AUWJEWJLSA-N 219741 US9303033, Z35, Table 39A, Compound 48 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219741 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219741&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335432 329994919 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384231 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(Oc3cccc4ccc(nc34)C#N)nc12 InChI=1S/C22H15N9O3/c23-9-14-5-4-11-2-1-3-16(17(11)25-14)34-22-28-18-12(8-15-19(32)29-21(33)27-15)10-24-31(18)20(30-22)26-13-6-7-13/h1-5,8,10,13H,6-7H2,(H,26,28,30)(H2,27,29,32,33)/b15-8- WXODCENIESBQPD-NVNXTCNLSA-N 219742 US9303033, A36, Table 39A, Compound 49 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219742 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219742&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335676 329994920 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384232 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(Oc3ccccc3-c3ccno3)nc12 InChI=1S/C21H16N8O4/c30-18-14(25-20(31)27-18)9-11-10-22-29-17(11)26-21(28-19(29)24-12-5-6-12)32-15-4-2-1-3-13(15)16-7-8-23-33-16/h1-4,7-10,12H,5-6H2,(H,24,26,28)(H2,25,27,30,31)/b14-9- SARWKPIOAIYQQL-ZROIWOOFSA-N 219743 US9303033, B36, Table 39A, Compound 50 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219743 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219743&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335897 329994921 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384233 Fc1cc(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)ccc1C#N InChI=1S/C19H13FN8O3/c20-13-6-12(4-1-9(13)7-21)31-19-25-15-10(5-14-16(29)26-18(30)24-14)8-22-28(15)17(27-19)23-11-2-3-11/h1,4-6,8,11H,2-3H2,(H,23,25,27)(H2,24,26,29,30)/b14-5- OXPWBYMBFCRNNX-RZNTYIFUSA-N 219744 US9303033, C36, Table 39A, Compound 51 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219744 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219744&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336188 329994922 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384234 Fc1ccc(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c(c1)-c1ccno1 InChI=1S/C21H15FN8O4/c22-11-1-4-15(13(8-11)16-5-6-24-34-16)33-21-27-17-10(7-14-18(31)28-20(32)26-14)9-23-30(17)19(29-21)25-12-2-3-12/h1,4-9,12H,2-3H2,(H,25,27,29)(H2,26,28,31,32)/b14-7- BAYMGFMNHJBERH-AUWJEWJLSA-N 219745 US9303033, D36, Table 39A, Compound 52 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219745 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219745&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335891 329994923 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384235 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(Oc3ccc(cc3)C3=NCCN3)nc12 InChI=1S/C21H19N9O3/c31-18-15(26-20(32)28-18)9-12-10-24-30-17(12)27-21(29-19(30)25-13-3-4-13)33-14-5-1-11(2-6-14)16-22-7-8-23-16/h1-2,5-6,9-10,13H,3-4,7-8H2,(H,22,23)(H,25,27,29)(H2,26,28,31,32)/b15-9- CQFWCSGKHYCWNW-DHDCSXOGSA-N 219746 US9303033, E36, Table 39A, Compound 53 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219746 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219746&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336096 329994924 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384236 COc1cc(CC#N)ccc1Oc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H18N8O4/c1-32-16-8-11(6-7-22)2-5-15(16)33-21-26-17-12(9-14-18(30)27-20(31)25-14)10-23-29(17)19(28-21)24-13-3-4-13/h2,5,8-10,13H,3-4,6H2,1H3,(H,24,26,28)(H2,25,27,30,31)/b14-9- MKKYNYVSTNCHIX-ZROIWOOFSA-N 219747 US9303033, F36, Table 39A, Compound 54 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219747 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219747&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335219 329994925 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384237 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(Oc3ccc(CC#N)cc3)nc12 InChI=1S/C20H16N8O3/c21-8-7-11-1-5-14(6-2-11)31-20-25-16-12(9-15-17(29)26-19(30)24-15)10-22-28(16)18(27-20)23-13-3-4-13/h1-2,5-6,9-10,13H,3-4,7H2,(H,23,25,27)(H2,24,26,29,30)/b15-9- WQSKHUIHHPGNEN-DHDCSXOGSA-N 219748 US9303033, G36, Table 39A, Compound 55 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219748 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219748&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336084 329994926 C04116 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384238 CN(C)c1cccc(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C20H20N8O3/c1-27(2)13-4-3-5-14(9-13)31-20-24-16-11(8-15-17(29)25-19(30)23-15)10-21-28(16)18(26-20)22-12-6-7-12/h3-5,8-10,12H,6-7H2,1-2H3,(H,22,24,26)(H2,23,25,29,30)/b15-8- TVHBCAAOXFUAJU-NVNXTCNLSA-N 219749 US9303033, H36, Table 39A, Compound 56 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219749 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219749&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335688 329994927 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384239 CCN(CC)c1cccc(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C22H24N8O3/c1-3-29(4-2)15-6-5-7-16(11-15)33-22-26-18-13(10-17-19(31)27-21(32)25-17)12-23-30(18)20(28-22)24-14-8-9-14/h5-7,10-12,14H,3-4,8-9H2,1-2H3,(H,24,26,28)(H2,25,27,31,32)/b17-10- AMBGXTRDULNOBE-YVLHZVERSA-N 219750 US9303033, I36, Table 39A, Compound 57 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219750 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219750&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335428 329994928 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384240 Cc1cc2cc(Oc3nc(NC4CC4)n4ncc(\C=C5/NC(=O)NC5=O)c4n3)ccc2[nH]1 InChI=1S/C21H18N8O3/c1-10-6-11-7-14(4-5-15(11)23-10)32-21-26-17-12(8-16-18(30)27-20(31)25-16)9-22-29(17)19(28-21)24-13-2-3-13/h4-9,13,23H,2-3H2,1H3,(H,24,26,28)(H2,25,27,30,31)/b16-8- LLXMPDLVJDPXLI-PXNMLYILSA-N 219751 US9303033, J36, Table 39A, Compound 58 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219751 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219751&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335433 329994929 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384241 CC(C)N1CCN(CC1)c1ccc(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C25H29N9O3/c1-15(2)32-9-11-33(12-10-32)18-5-7-19(8-6-18)37-25-29-21-16(13-20-22(35)30-24(36)28-20)14-26-34(21)23(31-25)27-17-3-4-17/h5-8,13-15,17H,3-4,9-12H2,1-2H3,(H,27,29,31)(H2,28,30,35,36)/b20-13- XXMCDIDYNPVKBF-MOSHPQCFSA-N 219752 US9303033, B48, Table 58A, Compound 25::US9303033, H49, Table 59A, Compound 18::US9303033, K36, Table 39A, Compound 59 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219752 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219752&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335490 329994930 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384242 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(OCc3ccccc3)nc12 InChI=1S/C19H17N7O3/c27-16-14(22-18(28)24-16)8-12-9-20-26-15(12)23-19(25-17(26)21-13-6-7-13)29-10-11-4-2-1-3-5-11/h1-5,8-9,13H,6-7,10H2,(H,21,23,25)(H2,22,24,27,28)/b14-8- UWYVZGCHYPPFQI-ZSOIEALJSA-N 219753 US9303033, L36, Example 231 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219753 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219753&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67255097 329994931 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384243 C[C@@H](Oc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1c(Cl)ccc(F)c1Cl InChI=1S/C20H16Cl2FN7O3/c1-8(14-11(21)4-5-12(23)15(14)22)33-20-27-16-9(6-13-17(31)28-19(32)26-13)7-24-30(16)18(29-20)25-10-2-3-10/h4-8,10H,2-3H2,1H3,(H,25,27,29)(H2,26,28,31,32)/b13-6-/t8-/m1/s1 XZPWHOFPBPUZBX-NWKJQJTJSA-N 219754 US9303033, M36, Table 40A, Compound 1 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219754&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335434 329994932 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384244 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(OCc3ccccn3)nc12 InChI=1S/C18H16N8O3/c27-15-13(22-17(28)24-15)7-10-8-20-26-14(10)23-18(25-16(26)21-11-4-5-11)29-9-12-3-1-2-6-19-12/h1-3,6-8,11H,4-5,9H2,(H,21,23,25)(H2,22,24,27,28)/b13-7- WCXOJKQVTKRNLO-QPEQYQDCSA-N 219755 US9303033, N36, Table 40A, Compound 2 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219755&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335895 329994933 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384245 N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H24N8O2/c20-11-1-3-12(4-2-11)22-15-8-16(23-13-5-6-13)27-17(25-15)10(9-21-27)7-14-18(28)26-19(29)24-14/h7-9,11-13,23H,1-6,20H2,(H,22,25)(H2,24,26,28,29)/b14-7-/t11-,12- BFKWWMRDPZCHKV-URQBRDCWSA-N 218886 US9303033, O36, Table 41A, Compound 1::US9303033, R2, Table 9A, Compound 3 Casein kinase II subunit beta 253.2 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218886 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218886&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67253135 329994109 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384246 CC(=O)N[C@H]1CCC(CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H26N8O3/c1-11(30)23-13-2-4-14(5-3-13)24-17-9-18(25-15-6-7-15)29-19(27-17)12(10-22-29)8-16-20(31)28-21(32)26-16/h8-10,13-15,25H,2-7H2,1H3,(H,23,30)(H,24,27)(H2,26,28,31,32)/b16-8-/t13-,14? KOWNENOOSKDGQV-QBUKKXEESA-N 218893 US9303033, A3, Table 10A, Compound 1::US9303033, D3, Table 10A, Compound 4::US9303033, P36, Table 41A, Compound 2 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218893 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218893&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67256299 329994116 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384247 CN(C)C(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H29N9O3/c1-30(2)22(34)26-15-7-3-13(4-8-15)24-17-10-18(25-14-5-6-14)31-19(28-17)12(11-23-31)9-16-20(32)29-21(33)27-16/h9-11,13-15,25H,3-8H2,1-2H3,(H,24,28)(H,26,34)(H2,27,29,32,33)/b16-9-/t13-,15- QQEUIJMSNYEALQ-AAMARJQVSA-N 219758 US9303033, Q36, Table 41A, Compound 3 Casein kinase II subunit beta 679.1 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219758 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219758&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67253200 329994934 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384248 CS(=O)(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H26N8O4S/c1-33(31,32)27-14-6-4-12(5-7-14)22-16-9-17(23-13-2-3-13)28-18(25-16)11(10-21-28)8-15-19(29)26-20(30)24-15/h8-10,12-14,23,27H,2-7H2,1H3,(H,22,25)(H2,24,26,29,30)/b15-8-/t12-,14- YQNATXAICQCDQY-WLOSUKBJSA-N 218897 US9303033, E3, Table 10A, Compound 5::US9303033, R36, Table 41A, Compound 4 Casein kinase II subunit beta 476 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218897 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218897&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335828 329994119 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384249 COC(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H26N8O4/c1-33-21(32)25-14-6-2-12(3-7-14)23-16-9-17(24-13-4-5-13)29-18(27-16)11(10-22-29)8-15-19(30)28-20(31)26-15/h8-10,12-14,24H,2-7H2,1H3,(H,23,27)(H,25,32)(H2,26,28,30,31)/b15-8-/t12-,14- DJXAOVVHHRACPC-WLOSUKBJSA-N 218895 US9303033, C3, Table 10A, Compound 3::US9303033, S36, Table 41A, Compound 5 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218895 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218895&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335515 329994118 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384250 CC(C)(C)OC(=O)N[C@H]1CCC(CC1)Nc1cc(N(C2CC2)C(=O)OC(C)(C)C)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C29H40N8O6/c1-28(2,3)42-26(40)32-18-9-7-17(8-10-18)31-21-14-22(36(19-11-12-19)27(41)43-29(4,5)6)37-23(34-21)16(15-30-37)13-20-24(38)35-25(39)33-20/h13-15,17-19H,7-12H2,1-6H3,(H,31,34)(H,32,40)(H2,33,35,38,39)/b20-13-/t17?,18- PXTAVDKANMIAFJ-VRVLZYMWSA-N 219761 US9303033, T36, Table 41A, Compound 6 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219761 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219761&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89888249 329994935 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384251 CCC(=O)N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H27N9O3/c1-2-16(31)23-12-3-5-13(6-4-12)24-19-27-17-11(9-15-18(32)28-21(33)26-15)10-22-30(17)20(29-19)25-14-7-8-14/h9-10,12-14H,2-8H2,1H3,(H,23,31)(H2,24,25,27,29)(H2,26,28,32,33)/b15-9-/t12-,13- IDQPGNAUNOEMOA-JNZTXQQWSA-N 219762 US9303033, U36, Table 41A, Compound 7 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219762&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335435 329994936 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384252 CCC(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H28N8O3/c1-2-19(31)26-15-7-3-13(4-8-15)24-17-10-18(25-14-5-6-14)30-20(28-17)12(11-23-30)9-16-21(32)29-22(33)27-16/h9-11,13-15,25H,2-8H2,1H3,(H,24,28)(H,26,31)(H2,27,29,32,33)/b16-9-/t13-,15- GNGMDOKZAYNPGC-AAMARJQVSA-N 219763 US9303033, V36, Table 41A, Compound 8 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219763 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219763&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67253944 329994937 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384253 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(N[C@H]3CC[C@@H](CC3)NS(=O)(=O)C3CC3)nc12 InChI=1S/C21H27N9O4S/c31-18-16(25-21(32)27-18)9-11-10-22-30-17(11)26-19(28-20(30)24-13-1-2-13)23-12-3-5-14(6-4-12)29-35(33,34)15-7-8-15/h9-10,12-15,29H,1-8H2,(H2,23,24,26,28)(H2,25,27,31,32)/b16-9-/t12-,14- XCGWADIXDBDCGX-OYQLBDEXSA-N 219764 US9303033, W36, Table 41A, Compound 9 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219764 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219764&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335893 329994938 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384254 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(N[C@H]3CC[C@@H](CC3)NS(=O)(=O)C3CC3)nc12 InChI=1S/C22H28N8O4S/c31-21-17(26-22(32)28-21)9-12-11-23-30-19(25-14-1-2-14)10-18(27-20(12)30)24-13-3-5-15(6-4-13)29-35(33,34)16-7-8-16/h9-11,13-16,25,29H,1-8H2,(H,24,27)(H2,26,28,31,32)/b17-9-/t13-,15- CFZXQTURHIVYLX-RKSCUSSWSA-N 219765 US9303033, X36, Table 41A, Compound 10 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219765 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219765&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335906 329994939 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384255 COCCOC(=O)N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H29N9O5/c1-35-8-9-36-22(34)26-15-6-2-13(3-7-15)24-19-28-17-12(10-16-18(32)29-21(33)27-16)11-23-31(17)20(30-19)25-14-4-5-14/h10-11,13-15H,2-9H2,1H3,(H,26,34)(H2,24,25,28,30)(H2,27,29,32,33)/b16-10-/t13-,15- MXBPDWFIVWCZNK-JEHBBDIFSA-N 219766 US9303033, Y36, Table 41A, Compound 11 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219766&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335244 329994940 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384256 COCCOC(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H30N8O5/c1-35-8-9-36-23(34)27-16-6-2-14(3-7-16)25-18-11-19(26-15-4-5-15)31-20(29-18)13(12-24-31)10-17-21(32)30-22(33)28-17/h10-12,14-16,26H,2-9H2,1H3,(H,25,29)(H,27,34)(H2,28,30,32,33)/b17-10-/t14-,16- SICWEILFSXFMPV-HKBWDPEPSA-N 219767 US9303033, Z36, Table 41A, Compound 12 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219767 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219767&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336088 329994941 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384257 CC(C)C(C)NC(=O)N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H34N10O3/c1-12(2)13(3)26-23(36)29-17-8-4-15(5-9-17)27-21-31-19-14(10-18-20(35)32-24(37)30-18)11-25-34(19)22(33-21)28-16-6-7-16/h10-13,15-17H,4-9H2,1-3H3,(H2,26,29,36)(H2,27,28,31,33)(H2,30,32,35,37)/b18-10-/t13?,15-,17- QJMVCLWVBKRLCT-ZLTCTZJESA-N 219768 US9303033, A37, Table 41A, Compound 13 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219768 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219768&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336204 329994942 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384258 CC(C)C(C)NC(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C25H35N9O3/c1-13(2)14(3)27-24(36)30-18-8-4-16(5-9-18)28-20-11-21(29-17-6-7-17)34-22(32-20)15(12-26-34)10-19-23(35)33-25(37)31-19/h10-14,16-18,29H,4-9H2,1-3H3,(H,28,32)(H2,27,30,36)(H2,31,33,35,37)/b19-10-/t14?,16-,18- GYJRFZVMZHSIRU-MPBHLCDISA-N 219769 US9303033, B37, Table 41A, Compound 14 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219769 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219769&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336097 329994943 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384259 CCCS(=O)(=O)N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H29N9O4S/c1-2-9-35(33,34)29-15-7-5-13(6-8-15)23-19-26-17-12(10-16-18(31)27-21(32)25-16)11-22-30(17)20(28-19)24-14-3-4-14/h10-11,13-15,29H,2-9H2,1H3,(H2,23,24,26,28)(H2,25,27,31,32)/b16-10-/t13-,15- ICLFTKXFSQOQTJ-JEHBBDIFSA-N 219770 US9303033, C37, Table 41A, Compound 15 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219770 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219770&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335903 329994944 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384260 CCCS(=O)(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H30N8O4S/c1-2-9-35(33,34)29-16-7-5-14(6-8-16)24-18-11-19(25-15-3-4-15)30-20(27-18)13(12-23-30)10-17-21(31)28-22(32)26-17/h10-12,14-16,25,29H,2-9H2,1H3,(H,24,27)(H2,26,28,31,32)/b17-10-/t14-,16- XRPPNXVVQSOQGH-HKBWDPEPSA-N 219771 US9303033, D37, Table 41A, Compound 16 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219771&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335913 329994945 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384261 FC(F)(F)CCS(=O)(=O)N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H26F3N9O4S/c22-21(23,24)7-8-38(36,37)32-14-5-3-12(4-6-14)26-18-29-16-11(9-15-17(34)30-20(35)28-15)10-25-33(16)19(31-18)27-13-1-2-13/h9-10,12-14,32H,1-8H2,(H2,26,27,29,31)(H2,28,30,34,35)/b15-9-/t12-,14- MEBXLDRBJWQLEV-RCBKHJBOSA-N 219772 US9303033, E37, Table 41A, Compound 17 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219772 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219772&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335250 329994946 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384262 FC(F)(F)CCS(=O)(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H27F3N8O4S/c23-22(24,25)7-8-38(36,37)32-15-5-3-13(4-6-15)27-17-10-18(28-14-1-2-14)33-19(30-17)12(11-26-33)9-16-20(34)31-21(35)29-16/h9-11,13-15,28,32H,1-8H2,(H,27,30)(H2,29,31,34,35)/b16-9-/t13-,15- AQAVJYRZBAYQEK-AAMARJQVSA-N 219773 US9303033, F37, Table 41A, Compound 18 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219773 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219773&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335919 329994947 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384263 CCCCS(=O)(=O)N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H31N9O4S/c1-2-3-10-36(34,35)30-16-8-6-14(7-9-16)24-20-27-18-13(11-17-19(32)28-22(33)26-17)12-23-31(18)21(29-20)25-15-4-5-15/h11-12,14-16,30H,2-10H2,1H3,(H2,24,25,27,29)(H2,26,28,32,33)/b17-11-/t14-,16- KBZILNLIYWZBBE-VUHPJLABSA-N 219774 US9303033, G37, Table 41A, Compound 19 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219774&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335690 329994948 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384264 CCCCS(=O)(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H32N8O4S/c1-2-3-10-36(34,35)30-17-8-6-15(7-9-17)25-19-12-20(26-16-4-5-16)31-21(28-19)14(13-24-31)11-18-22(32)29-23(33)27-18/h11-13,15-17,26,30H,2-10H2,1H3,(H,25,28)(H2,27,29,32,33)/b18-11-/t15-,17- GKEMDUPJKUUOJH-SBCQGGEXSA-N 219775 US9303033, H37, Table 41A, Compound 20 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219775&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335443 329994949 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384265 CC(C)CS(=O)(=O)N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H31N9O4S/c1-12(2)11-36(34,35)30-16-7-5-14(6-8-16)24-20-27-18-13(9-17-19(32)28-22(33)26-17)10-23-31(18)21(29-20)25-15-3-4-15/h9-10,12,14-16,30H,3-8,11H2,1-2H3,(H2,24,25,27,29)(H2,26,28,32,33)/b17-9-/t14-,16- GKWBKEFNKBPNMM-ACPNVMACSA-N 219776 US9303033, I37, Table 41A, Compound 21 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219776 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219776&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335251 329994950 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384266 CC(C)CS(=O)(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H32N8O4S/c1-13(2)12-36(34,35)30-17-7-5-15(6-8-17)25-19-10-20(26-16-3-4-16)31-21(28-19)14(11-24-31)9-18-22(32)29-23(33)27-18/h9-11,13,15-17,26,30H,3-8,12H2,1-2H3,(H,25,28)(H2,27,29,32,33)/b18-9-/t15-,17- OPXQOXJBICUGND-YQCWQGMOSA-N 219777 US9303033, J37, Table 41A, Compound 22 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219777&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335914 329994951 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384267 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(N[C@H]3CC[C@@H](CC3)NS(=O)(=O)Cc3ccccc3)nc12 InChI=1S/C25H29N9O4S/c35-22-20(29-25(36)31-22)12-16-13-26-34-21(16)30-23(32-24(34)28-18-6-7-18)27-17-8-10-19(11-9-17)33-39(37,38)14-15-4-2-1-3-5-15/h1-5,12-13,17-19,33H,6-11,14H2,(H2,27,28,30,32)(H2,29,31,35,36)/b20-12-/t17-,19- VWHQRTCPMWIEAA-JDVBLMHDSA-N 219778 US9303033, K37, Table 41A, Compound 23 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219778 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219778&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336196 329994952 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384268 Fc1ccccc1S(=O)(=O)N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H26FN9O4S/c25-17-3-1-2-4-19(17)39(37,38)33-16-9-7-14(8-10-16)27-22-30-20-13(11-18-21(35)31-24(36)29-18)12-26-34(20)23(32-22)28-15-5-6-15/h1-4,11-12,14-16,33H,5-10H2,(H2,27,28,30,32)(H2,29,31,35,36)/b18-11-/t14-,16- HEHYGHRKZVPQQG-KIRPUACZSA-N 219779 US9303033, L37, Table 41A, Compound 24 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219779 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219779&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335693 329994953 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384269 Fc1ccccc1S(=O)(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C25H27FN8O4S/c26-18-3-1-2-4-20(18)39(37,38)33-17-9-7-15(8-10-17)28-21-12-22(29-16-5-6-16)34-23(31-21)14(13-27-34)11-19-24(35)32-25(36)30-19/h1-4,11-13,15-17,29,33H,5-10H2,(H,28,31)(H2,30,32,35,36)/b19-11-/t15-,17- YBJDGLGXHFSLLY-YMKLMEOPSA-N 219780 US9303033, M37, Table 41A, Compound 25 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219780 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219780&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336075 329994954 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384270 Fc1cccc(c1)S(=O)(=O)N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H26FN9O4S/c25-14-2-1-3-18(11-14)39(37,38)33-17-8-6-15(7-9-17)27-22-30-20-13(10-19-21(35)31-24(36)29-19)12-26-34(20)23(32-22)28-16-4-5-16/h1-3,10-12,15-17,33H,4-9H2,(H2,27,28,30,32)(H2,29,31,35,36)/b19-10-/t15-,17- FUEUHFRHPAZHJS-FANUVMDLSA-N 219781 US9303033, N37, Table 41A, Compound 26 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219781 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219781&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335447 329994955 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384271 Fc1cccc(c1)S(=O)(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C25H27FN8O4S/c26-15-2-1-3-19(11-15)39(37,38)33-18-8-6-16(7-9-18)28-21-12-22(29-17-4-5-17)34-23(31-21)14(13-27-34)10-20-24(35)32-25(36)30-20/h1-3,10-13,16-18,29,33H,4-9H2,(H,28,31)(H2,30,32,35,36)/b20-10-/t16-,18- GNMFLIAQZZOYSP-QYVQVOCESA-N 219782 US9303033, O37, Table 41A, Compound 27 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219782&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335246 329994956 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384272 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(N[C@H]3CC[C@@H](CC3)NS(=O)(=O)c3ccccc3C#N)nc12 InChI=1S/C25H26N10O4S/c26-12-14-3-1-2-4-20(14)40(38,39)34-18-9-7-16(8-10-18)28-23-31-21-15(11-19-22(36)32-25(37)30-19)13-27-35(21)24(33-23)29-17-5-6-17/h1-4,11,13,16-18,34H,5-10H2,(H2,28,29,31,33)(H2,30,32,36,37)/b19-11-/t16-,18- HKKLDLDFZZJDIN-UUCHLSOYSA-N 219783 US9303033, P37, Table 41A, Compound 28 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219783 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219783&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335916 329994957 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384273 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(N[C@H]3CC[C@@H](CC3)NS(=O)(=O)c3ccccc3C#N)nc12 InChI=1S/C26H27N9O4S/c27-13-15-3-1-2-4-21(15)40(38,39)34-19-9-7-17(8-10-19)29-22-12-23(30-18-5-6-18)35-24(32-22)16(14-28-35)11-20-25(36)33-26(37)31-20/h1-4,11-12,14,17-19,30,34H,5-10H2,(H,29,32)(H2,31,33,36,37)/b20-11-/t17-,19- ZZDBRQVCRBGYQQ-URTJRZIRSA-N 219784 US9303033, Q37, Table 41A, Compound 29 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219784&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336201 329994958 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384274 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(N[C@H]3CC[C@@H](CC3)NS(=O)(=O)c3cccc(c3)C#N)nc12 InChI=1S/C25H26N10O4S/c26-12-14-2-1-3-19(10-14)40(38,39)34-18-8-6-16(7-9-18)28-23-31-21-15(11-20-22(36)32-25(37)30-20)13-27-35(21)24(33-23)29-17-4-5-17/h1-3,10-11,13,16-18,34H,4-9H2,(H2,28,29,31,33)(H2,30,32,36,37)/b20-11-/t16-,18- UDRLTZIQMKICOH-QDZQTYHFSA-N 219785 US9303033, R37, Table 41A, Compound 30 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219785&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336206 329994959 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384275 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(N[C@H]3CC[C@@H](CC3)NS(=O)(=O)c3cccc(c3)C#N)nc12 InChI=1S/C26H27N9O4S/c27-13-15-2-1-3-20(10-15)40(38,39)34-19-8-6-17(7-9-19)29-22-12-23(30-18-4-5-18)35-24(32-22)16(14-28-35)11-21-25(36)33-26(37)31-21/h1-3,10-12,14,17-19,30,34H,4-9H2,(H,29,32)(H2,31,33,36,37)/b21-11-/t17-,19- DZMWEQILLGGIHD-HPJHBVMLSA-N 219786 US9303033, S37, Table 41A, Compound 31 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219786&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335900 329994960 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384276 Fc1ccc(c(F)c1)S(=O)(=O)N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H25F2N9O4S/c25-13-1-8-19(17(26)10-13)40(38,39)34-16-6-4-14(5-7-16)28-22-31-20-12(9-18-21(36)32-24(37)30-18)11-27-35(20)23(33-22)29-15-2-3-15/h1,8-11,14-16,34H,2-7H2,(H2,28,29,31,33)(H2,30,32,36,37)/b18-9-/t14-,16- QGKOTRPSRKVCJE-CEJLKXFESA-N 219787 US9303033, T37, Table 41A, Compound 32 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219787&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335277 329994961 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384277 Fc1ccc(c(F)c1)S(=O)(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C25H26F2N8O4S/c26-14-1-8-20(18(27)10-14)40(38,39)34-17-6-4-15(5-7-17)29-21-11-22(30-16-2-3-16)35-23(32-21)13(12-28-35)9-19-24(36)33-25(37)31-19/h1,8-12,15-17,30,34H,2-7H2,(H,29,32)(H2,31,33,36,37)/b19-9-/t15-,17- RTTZTZWNXHGKFM-CZPSMWBFSA-N 219788 US9303033, U37, Table 41A, Compound 33 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219788&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335283 329994962 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384278 O=C(CC1CC1)N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H29N9O3/c33-18(9-12-1-2-12)25-14-3-5-15(6-4-14)26-21-29-19-13(10-17-20(34)30-23(35)28-17)11-24-32(19)22(31-21)27-16-7-8-16/h10-12,14-16H,1-9H2,(H,25,33)(H2,26,27,29,31)(H2,28,30,34,35)/b17-10-/t14-,15- GGHDVXJEAFPLAL-HJGBLPHTSA-N 219789 US9303033, V37, Table 41A, Compound 34 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219789 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219789&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335451 329994963 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384279 O=C(CC1CC1)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H30N8O3/c33-21(9-13-1-2-13)28-17-7-3-15(4-8-17)26-19-11-20(27-16-5-6-16)32-22(30-19)14(12-25-32)10-18-23(34)31-24(35)29-18/h10-13,15-17,27H,1-9H2,(H,26,30)(H,28,33)(H2,29,31,34,35)/b18-10-/t15-,17- LRJHBYZSFZMVLY-KTZIATJXSA-N 219790 US9303033, W37, Table 41A, Compound 35 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219790&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335689 329994964 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384280 CC1(CC1)C(=O)N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H29N9O3/c1-23(8-9-23)19(34)25-13-2-4-14(5-3-13)26-20-29-17-12(10-16-18(33)30-22(35)28-16)11-24-32(17)21(31-20)27-15-6-7-15/h10-11,13-15H,2-9H2,1H3,(H,25,34)(H2,26,27,29,31)(H2,28,30,33,35)/b16-10-/t13-,14- HPBFUCJUVCAWAD-CCYAHBIWSA-N 219791 US9303033, X37, Table 41A, Compound 36 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219791&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335295 329994965 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384281 CC1(CC1)C(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H30N8O3/c1-24(8-9-24)22(34)28-16-6-2-14(3-7-16)26-18-11-19(27-15-4-5-15)32-20(30-18)13(12-25-32)10-17-21(33)31-23(35)29-17/h10-12,14-16,27H,2-9H2,1H3,(H,26,30)(H,28,34)(H2,29,31,33,35)/b17-10-/t14-,16- RWPZDIBQLDPCCB-HKBWDPEPSA-N 219792 US9303033, Y37, Table 41A, Compound 37 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219792&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335904 329994966 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384282 CC1CC1C(=O)N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H29N9O3/c1-11-8-16(11)19(33)25-13-2-4-14(5-3-13)26-21-29-18-12(9-17-20(34)30-23(35)28-17)10-24-32(18)22(31-21)27-15-6-7-15/h9-11,13-16H,2-8H2,1H3,(H,25,33)(H2,26,27,29,31)(H2,28,30,34,35)/b17-9-/t11?,13-,14-,16? OGPQYUHAWMORIN-ONVOUZOSSA-N 219793 US9303033, Z37, Table 41A, Compound 38 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219793&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335902 329994967 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384283 CC1CC1C(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H30N8O3/c1-12-8-17(12)22(33)28-16-6-2-14(3-7-16)26-19-10-20(27-15-4-5-15)32-21(30-19)13(11-25-32)9-18-23(34)31-24(35)29-18/h9-12,14-17,27H,2-8H2,1H3,(H,26,30)(H,28,33)(H2,29,31,34,35)/b18-9-/t12?,14-,16-,17? DTHKOXUXMYRVNZ-FHJSTBRPSA-N 219794 US9303033, A38, Table 41A, Compound 39 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219794&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335692 329994968 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384284 O=C(N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C1CCC1 InChI=1S/C23H29N9O3/c33-19(12-2-1-3-12)25-14-4-6-15(7-5-14)26-21-29-18-13(10-17-20(34)30-23(35)28-17)11-24-32(18)22(31-21)27-16-8-9-16/h10-12,14-16H,1-9H2,(H,25,33)(H2,26,27,29,31)(H2,28,30,34,35)/b17-10-/t14-,15- BSNUVJBTCSOABH-HJGBLPHTSA-N 219795 US9303033, B38, Table 41A, Compound 40 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219795 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219795&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335281 329994969 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384285 O=C(N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C1CCC1 InChI=1S/C24H30N8O3/c33-22(13-2-1-3-13)28-17-8-4-15(5-9-17)26-19-11-20(27-16-6-7-16)32-21(30-19)14(12-25-32)10-18-23(34)31-24(35)29-18/h10-13,15-17,27H,1-9H2,(H,26,30)(H,28,33)(H2,29,31,34,35)/b18-10-/t15-,17- PVUDYFYEKUGCCF-KTZIATJXSA-N 219796 US9303033, C38, Table 41A, Compound 41 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219796&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335270 329994970 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384286 O=C(N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C1(CC1)C#N InChI=1S/C23H26N10O3/c24-11-23(7-8-23)19(35)26-13-1-3-14(4-2-13)27-20-30-17-12(9-16-18(34)31-22(36)29-16)10-25-33(17)21(32-20)28-15-5-6-15/h9-10,13-15H,1-8H2,(H,26,35)(H2,27,28,30,32)(H2,29,31,34,36)/b16-9-/t13-,14- JERODNYRQVNCSF-YCKYOMLYSA-N 219797 US9303033, D38, Table 41A, Compound 42 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219797&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335292 329994971 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384287 O=C(N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C1(CC1)C#N InChI=1S/C24H27N9O3/c25-12-24(7-8-24)22(35)29-16-5-1-14(2-6-16)27-18-10-19(28-15-3-4-15)33-20(31-18)13(11-26-33)9-17-21(34)32-23(36)30-17/h9-11,14-16,28H,1-8H2,(H,27,31)(H,29,35)(H2,30,32,34,36)/b17-9-/t14-,16- IYSAVKHZVMUFFQ-ACPNVMACSA-N 219798 US9303033, E38, Table 41A, Compound 43 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219798&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336090 329994972 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384288 FC1(F)CC1C(=O)N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H25F2N9O3/c23-22(24)8-14(22)17(34)26-11-1-3-12(4-2-11)27-19-30-16-10(7-15-18(35)31-21(36)29-15)9-25-33(16)20(32-19)28-13-5-6-13/h7,9,11-14H,1-6,8H2,(H,26,34)(H2,27,28,30,32)(H2,29,31,35,36)/b15-7-/t11-,12-,14? VDYXOCDDOJJUIK-PVOOEDNYSA-N 219799 US9303033, F38, Table 41A, Compound 44 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219799&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335917 329994973 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384289 FC1(F)CC1C(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H26F2N8O3/c24-23(25)9-15(23)20(34)29-14-5-1-12(2-6-14)27-17-8-18(28-13-3-4-13)33-19(31-17)11(10-26-33)7-16-21(35)32-22(36)30-16/h7-8,10,12-15,28H,1-6,9H2,(H,27,31)(H,29,34)(H2,30,32,35,36)/b16-7-/t12-,14-,15? YSAASCDMJJWNGI-XWMVHJNJSA-N 219800 US9303033, G38, Table 41A, Compound 45 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219800&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336092 329994974 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384290 O=C(CN1CCCCC1)N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C25H34N10O3/c36-20(14-34-10-2-1-3-11-34)27-16-4-6-17(7-5-16)28-23-31-21-15(12-19-22(37)32-25(38)30-19)13-26-35(21)24(33-23)29-18-8-9-18/h12-13,16-18H,1-11,14H2,(H,27,36)(H2,28,29,31,33)(H2,30,32,37,38)/b19-12-/t16-,17- KECDEXXKYHIXJV-DWBADKDHSA-N 219801 US9303033, H38, Table 41A, Compound 46 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219801 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219801&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336095 329994975 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384291 O=C(CN1CCCCC1)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C26H35N9O3/c36-23(15-34-10-2-1-3-11-34)30-19-8-4-17(5-9-19)28-21-13-22(29-18-6-7-18)35-24(32-21)16(14-27-35)12-20-25(37)33-26(38)31-20/h12-14,17-19,29H,1-11,15H2,(H,28,32)(H,30,36)(H2,31,33,37,38)/b20-12-/t17-,19- SPKQXCYNRMEKPC-JDVBLMHDSA-N 219802 US9303033, I38, Table 41A, Compound 47 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219802&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335436 329994976 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384292 O=C(CCN1CCCC1)N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C25H34N10O3/c36-20(9-12-34-10-1-2-11-34)27-16-3-5-17(6-4-16)28-23-31-21-15(13-19-22(37)32-25(38)30-19)14-26-35(21)24(33-23)29-18-7-8-18/h13-14,16-18H,1-12H2,(H,27,36)(H2,28,29,31,33)(H2,30,32,37,38)/b19-13-/t16-,17- LYXCOFWLXSTEFL-AVZOKDFDSA-N 219803 US9303033, J38, Table 41A, Compound 48 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219803&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336207 329994977 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384293 O=C(CCN1CCCC1)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C26H35N9O3/c36-23(9-12-34-10-1-2-11-34)30-19-7-3-17(4-8-19)28-21-14-22(29-18-5-6-18)35-24(32-21)16(15-27-35)13-20-25(37)33-26(38)31-20/h13-15,17-19,29H,1-12H2,(H,28,32)(H,30,36)(H2,31,33,37,38)/b20-13-/t17-,19- PGOIHGRYPSJCHC-SOEVKJKVSA-N 219804 US9303033, K38, Table 41A, Compound 49 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219804 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219804&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335911 329994978 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384294 CC(N1CCCC1)C(=O)N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C25H34N10O3/c1-14(34-10-2-3-11-34)21(36)27-16-4-6-17(7-5-16)28-23-31-20-15(12-19-22(37)32-25(38)30-19)13-26-35(20)24(33-23)29-18-8-9-18/h12-14,16-18H,2-11H2,1H3,(H,27,36)(H2,28,29,31,33)(H2,30,32,37,38)/b19-12-/t14?,16-,17- FHGAYCHBEWJHQZ-HHUBOPOISA-N 219805 US9303033, L38, Table 41A, Compound 50 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219805&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335920 329994979 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384295 CC(N1CCCC1)C(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C26H35N9O3/c1-15(34-10-2-3-11-34)24(36)30-19-8-4-17(5-9-19)28-21-13-22(29-18-6-7-18)35-23(32-21)16(14-27-35)12-20-25(37)33-26(38)31-20/h12-15,17-19,29H,2-11H2,1H3,(H,28,32)(H,30,36)(H2,31,33,37,38)/b20-12-/t15?,17-,19- ASKFQCKMOCVFQI-CKEUUVCCSA-N 219806 US9303033, M38, Table 41A, Compound 51 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219806&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335291 329994980 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384296 O=C(CN1CCOCC1)N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H32N10O4/c35-19(13-33-7-9-38-10-8-33)26-15-1-3-16(4-2-15)27-22-30-20-14(11-18-21(36)31-24(37)29-18)12-25-34(20)23(32-22)28-17-5-6-17/h11-12,15-17H,1-10,13H2,(H,26,35)(H2,27,28,30,32)(H2,29,31,36,37)/b18-11-/t15-,16- WOIDFINVIBSQCD-JPBSBIHGSA-N 219807 US9303033, N38, Table 41A, Compound 52 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219807&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336101 329994981 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384297 O=C(CN1CCOCC1)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C25H33N9O4/c35-22(14-33-7-9-38-10-8-33)29-18-5-1-16(2-6-18)27-20-12-21(28-17-3-4-17)34-23(31-20)15(13-26-34)11-19-24(36)32-25(37)30-19/h11-13,16-18,28H,1-10,14H2,(H,27,31)(H,29,35)(H2,30,32,36,37)/b19-11-/t16-,18- XWWHMSLNFBJYSV-UUCHLSOYSA-N 219808 US9303033, O38, Table 41A, Compound 53 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219808&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335247 329994982 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384298 FC(F)(F)C1(CC1)C(=O)N[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H26F3N9O3/c24-23(25,26)22(7-8-22)18(37)28-12-1-3-13(4-2-12)29-19-32-16-11(9-15-17(36)33-21(38)31-15)10-27-35(16)20(34-19)30-14-5-6-14/h9-10,12-14H,1-8H2,(H,28,37)(H2,29,30,32,34)(H2,31,33,36,38)/b15-9-/t12-,13- IFKQKXWTHZSFOU-JNZTXQQWSA-N 219809 US9303033, P38, Table 41A, Compound 54 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219809&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335456 329994983 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384299 FC(F)(F)C1(CC1)C(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H27F3N8O3/c25-24(26,27)23(7-8-23)21(37)31-15-5-1-13(2-6-15)29-17-10-18(30-14-3-4-14)35-19(33-17)12(11-28-35)9-16-20(36)34-22(38)32-16/h9-11,13-15,30H,1-8H2,(H,29,33)(H,31,37)(H2,32,34,36,38)/b16-9-/t13-,15- NNBVSENUCFXJIU-AAMARJQVSA-N 219810 US9303033, Q38, Table 41A, Compound 55 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219810 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219810&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335293 329994984 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384300 CN1CCN(CC(=O)N[C@H]2CC[C@@H](CC2)Nc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)CC1 InChI=1S/C25H35N11O3/c1-34-8-10-35(11-9-34)14-20(37)27-16-2-4-17(5-3-16)28-23-31-21-15(12-19-22(38)32-25(39)30-19)13-26-36(21)24(33-23)29-18-6-7-18/h12-13,16-18H,2-11,14H2,1H3,(H,27,37)(H2,28,29,31,33)(H2,30,32,38,39)/b19-12-/t16-,17- QHESEHNFQFGHML-DWBADKDHSA-N 219811 US9303033, R38, Table 41A, Compound 56 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219811 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219811&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335915 329994985 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384301 CN1CCN(CC(=O)N[C@H]2CC[C@@H](CC2)Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)CC1 InChI=1S/C26H36N10O3/c1-34-8-10-35(11-9-34)15-23(37)30-19-6-2-17(3-7-19)28-21-13-22(29-18-4-5-18)36-24(32-21)16(14-27-36)12-20-25(38)33-26(39)31-20/h12-14,17-19,29H,2-11,15H2,1H3,(H,28,32)(H,30,37)(H2,31,33,38,39)/b20-12-/t17-,19- GEWYACBQKWWUPS-JDVBLMHDSA-N 219812 US9303033, S38, Table 41A, Compound 57 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219812 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219812&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336085 329994986 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384302 CC(C)CN[C@H]1CC[C@@H](CC1)Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H31N9O2/c1-12(2)10-23-14-3-5-15(6-4-14)25-20-28-18-13(9-17-19(32)29-22(33)27-17)11-24-31(18)21(30-20)26-16-7-8-16/h9,11-12,14-16,23H,3-8,10H2,1-2H3,(H2,25,26,28,30)(H2,27,29,32,33)/b17-9-/t14-,15- BYALRTMHRQHOIZ-MDYDWWASSA-N 219813 US9303033, T38, Table 41A, Compound 58 Casein kinase II subunit beta >1000 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219813 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219813&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67254829 329994987 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384303 Clc1cccc(Oc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C19H15ClN6O3/c20-11-2-1-3-13(7-11)29-16-8-15(22-12-4-5-12)26-17(24-16)10(9-21-26)6-14-18(27)25-19(28)23-14/h1-3,6-9,12,22H,4-5H2,(H2,23,25,27,28)/b14-6- NEUNGLKFGZTDAL-NSIKDUERSA-N 219814 US9303033, U38, Table 42A, Compound 1 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219814 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219814&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67254736 329994988 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384304 Clc1cc(ccc1Oc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C#N InChI=1S/C20H14ClN7O3/c21-13-5-10(8-22)1-4-15(13)31-17-7-16(24-12-2-3-12)28-18(26-17)11(9-23-28)6-14-19(29)27-20(30)25-14/h1,4-7,9,12,24H,2-3H2,(H2,25,27,29,30)/b14-6- FOGCNJQZHYCMFI-NSIKDUERSA-N 219815 US9303033, V38, Table 42A, Compound 2 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219815 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219815&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335455 329994989 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384305 CC(=O)N1CCN(CC1)c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H22N8O3/c1-11(28)25-4-6-26(7-5-25)15-9-16(21-13-2-3-13)27-17(23-15)12(10-20-27)8-14-18(29)24-19(30)22-14/h8-10,13,21H,2-7H2,1H3,(H2,22,24,29,30)/b14-8- ZCPILKDDOATINX-ZSOIEALJSA-N 220025 US9303033, U46, Table 57A, Compound 1 Casein kinase II subunit beta 42842 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220025&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 89888230 329995188 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384306 O=C(C1CC1)N1CCN(CC1)c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H24N8O3/c30-19-15(24-21(32)26-19)9-13-11-22-29-17(23-14-3-4-14)10-16(25-18(13)29)27-5-7-28(8-6-27)20(31)12-1-2-12/h9-12,14,23H,1-8H2,(H2,24,26,30,32)/b15-9- GJALBHOAIMJJLI-DHDCSXOGSA-N 220026 US9303033, V46, Table 57A, Compound 2 Casein kinase II subunit beta 38513 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220026&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 71114390 329995189 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384307 FC(F)(F)C1(CC1)C(=O)N1CCN(CC1)c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H23F3N8O3/c23-22(24,25)21(3-4-21)19(35)32-7-5-31(6-8-32)15-10-16(27-13-1-2-13)33-17(29-15)12(11-26-33)9-14-18(34)30-20(36)28-14/h9-11,13,27H,1-8H2,(H2,28,30,34,36)/b14-9- BXFLCLIUJGTFTB-ZROIWOOFSA-N 220027 US9303033, W46, Table 57A, Compound 3 Casein kinase II subunit beta 70354 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220027&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336006 329995190 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384308 O=C(C1CCC1)N1CCN(CC1)c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H26N8O3/c31-20-16(25-22(33)27-20)10-14-12-23-30-18(24-15-4-5-15)11-17(26-19(14)30)28-6-8-29(9-7-28)21(32)13-2-1-3-13/h10-13,15,24H,1-9H2,(H2,25,27,31,33)/b16-10- ZBTGRDCFPHFAGA-YBEGLDIGSA-N 220028 US9303033, X46, Table 57A, Compound 4 Casein kinase II subunit beta 41170 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220028&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 71114385 329995191 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384309 O=C(CN1CCOCC1)N1CCN(CC1)c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H29N9O4/c33-20(14-29-7-9-36-10-8-29)31-5-3-30(4-6-31)18-12-19(25-16-1-2-16)32-21(27-18)15(13-24-32)11-17-22(34)28-23(35)26-17/h11-13,16,25H,1-10,14H2,(H2,26,28,34,35)/b17-11- HVMGYPYCSCRYBR-BOPFTXTBSA-N 220029 US9303033, Y46, Table 57A, Compound 5 Casein kinase II subunit beta 52820 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220029&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336257 329995192 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384310 CC(C)(C)OC(=O)N1CCN(CC1)c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H28N8O4/c1-22(2,3)34-21(33)29-8-6-28(7-9-29)16-11-17(24-14-4-5-14)30-18(26-16)13(12-23-30)10-15-19(31)27-20(32)25-15/h10-12,14,24H,4-9H2,1-3H3,(H2,25,27,31,32)/b15-10- LVARICONRYDKIM-GDNBJRDFSA-N 220030 US9303033, Z46, Table 57A, Compound 6 Casein kinase II subunit beta 51843 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220030&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67255515 329995193 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384311 CC1(CC1)C(=O)N1CCN(CC1)c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H26N8O3/c1-22(4-5-22)20(32)29-8-6-28(7-9-29)16-11-17(24-14-2-3-14)30-18(26-16)13(12-23-30)10-15-19(31)27-21(33)25-15/h10-12,14,24H,2-9H2,1H3,(H2,25,27,31,33)/b15-10- VBPMXGNBEBYHJI-GDNBJRDFSA-N 220031 US9303033, A47, Table 57A, Compound 7 Casein kinase II subunit beta 60724 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220031&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336251 329995194 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384312 FC1(F)CC1C(=O)N1CCN(CC1)c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H22F2N8O3/c22-21(23)9-13(21)19(33)30-5-3-29(4-6-30)15-8-16(25-12-1-2-12)31-17(27-15)11(10-24-31)7-14-18(32)28-20(34)26-14/h7-8,10,12-13,25H,1-6,9H2,(H2,26,28,32,34)/b14-7- XLDPATMKVYWXOK-AUWJEWJLSA-N 220032 US9303033, B47, Table 57A, Compound 8 Casein kinase II subunit beta 41017 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220032&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335734 329995195 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384313 O=C(CC1CC1)N1CCN(CC1)c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H26N8O3/c31-19(9-13-1-2-13)29-7-5-28(6-8-29)17-11-18(24-15-3-4-15)30-20(26-17)14(12-23-30)10-16-21(32)27-22(33)25-16/h10-13,15,24H,1-9H2,(H2,25,27,32,33)/b16-10- DJDIZUSJIOWTBU-YBEGLDIGSA-N 220033 US9303033, C47, Table 57A, Compound 9 Casein kinase II subunit beta 3668 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220033&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313849 329995196 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384314 O=C(Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C1CNCCO1 InChI=1S/C18H20N8O4/c27-16-11(22-18(29)25-16)5-9-7-20-26-14(21-10-1-2-10)6-13(23-15(9)26)24-17(28)12-8-19-3-4-30-12/h5-7,10,12,19,21H,1-4,8H2,(H,23,24,28)(H2,22,25,27,29)/b11-5- ALJCIPGXDJVJSG-WZUFQYTHSA-N 220039 US9303033, I47, Table 58A, Compound 6 Casein kinase II subunit beta 45534 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220039&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336179 329995202 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384315 CCNC(=O)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C16H18N8O3/c1-2-17-15(26)22-11-6-12(19-9-3-4-9)24-13(21-11)8(7-18-24)5-10-14(25)23-16(27)20-10/h5-7,9,19H,2-4H2,1H3,(H2,17,21,22,26)(H2,20,23,25,27)/b10-5- HTNSAFNSBVKMAA-YHYXMXQVSA-N 220041 US9303033, K47, Table 58A, Compound 8 Casein kinase II subunit beta 24910 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220041 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220041&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335745 329995204 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384316 O=C(Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccncn1 InChI=1S/C18H15N9O3/c28-16(11-3-4-19-8-20-11)25-13-6-14(22-10-1-2-10)27-15(24-13)9(7-21-27)5-12-17(29)26-18(30)23-12/h3-8,10,22H,1-2H2,(H,24,25,28)(H2,23,26,29,30)/b12-5- YNCYGFGZHKUZDJ-XGICHPGQSA-N 220042 US9303033, L47, Table 58A, Compound 9 Casein kinase II subunit beta 34040 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220042&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335348 329995205 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384317 O=C(Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1cnsc1 InChI=1S/C17H14N8O3S/c26-15(9-6-19-29-7-9)23-12-4-13(20-10-1-2-10)25-14(22-12)8(5-18-25)3-11-16(27)24-17(28)21-11/h3-7,10,20H,1-2H2,(H,22,23,26)(H2,21,24,27,28)/b11-3- TWIUEVAZDKIVMM-JYOAFUTRSA-N 220043 US9303033, M47, Table 58A, Compound 10 Casein kinase II subunit beta 8709 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220043&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335747 329995206 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384318 Fc1cccc(c1)C(=O)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H16FN7O3/c21-12-3-1-2-10(6-12)18(29)26-15-8-16(23-13-4-5-13)28-17(25-15)11(9-22-28)7-14-19(30)27-20(31)24-14/h1-3,6-9,13,23H,4-5H2,(H,25,26,29)(H2,24,27,30,31)/b14-7- CZQAFKNGARPOKB-AUWJEWJLSA-N 220046 US9303033, P47, Table 58A, Compound 13 Casein kinase II subunit beta 19381 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220046&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335754 329995209 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384319 Fc1ccc(Cl)cc1C(=O)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H15ClFN7O3/c21-10-1-4-13(22)12(6-10)18(30)27-15-7-16(24-11-2-3-11)29-17(26-15)9(8-23-29)5-14-19(31)28-20(32)25-14/h1,4-8,11,24H,2-3H2,(H,26,27,30)(H2,25,28,31,32)/b14-5- AHNNLAHFOYPQLX-RZNTYIFUSA-N 220048 US9303033, R47, Table 58A, Compound 15 Casein kinase II subunit beta 35033 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220048&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335756 329995211 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384320 Fc1ccc(C(=O)Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c(F)c1 InChI=1S/C20H15F2N7O3/c21-10-1-4-12(13(22)6-10)18(30)27-15-7-16(24-11-2-3-11)29-17(26-15)9(8-23-29)5-14-19(31)28-20(32)25-14/h1,4-8,11,24H,2-3H2,(H,26,27,30)(H2,25,28,31,32)/b14-5- XGACHZITAXTTLM-RZNTYIFUSA-N 220049 US9303033, S47, Table 58A, Compound 16 Casein kinase II subunit beta 23660 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220049 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220049&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335355 329995212 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384321 Fc1c(Cl)cccc1C(=O)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H15ClFN7O3/c21-12-3-1-2-11(16(12)22)18(30)27-14-7-15(24-10-4-5-10)29-17(26-14)9(8-23-29)6-13-19(31)28-20(32)25-13/h1-3,6-8,10,24H,4-5H2,(H,26,27,30)(H2,25,28,31,32)/b13-6- CMNXJVSRKIPLRI-MLPAPPSSSA-N 220050 US9303033, T47, Table 58A, Compound 17 Casein kinase II subunit beta 2891 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220050 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220050&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336173 329995213 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384322 C[C@@H](NC(=O)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C1CC1 InChI=1S/C19H22N8O3/c1-9(10-2-3-10)21-18(29)25-14-7-15(22-12-4-5-12)27-16(24-14)11(8-20-27)6-13-17(28)26-19(30)23-13/h6-10,12,22H,2-5H2,1H3,(H2,21,24,25,29)(H2,23,26,28,30)/b13-6-/t9-/m1/s1 COGOUZZLIFLGQM-JHFYRWCBSA-N 220051 US9303033, U47, Table 58A, Compound 18 Casein kinase II subunit beta 19928 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220051&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336177 329995214 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384323 COc1cc(Cl)ccc1C(=O)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H18ClN7O4/c1-33-15-7-11(22)2-5-13(15)19(30)27-16-8-17(24-12-3-4-12)29-18(26-16)10(9-23-29)6-14-20(31)28-21(32)25-14/h2,5-9,12,24H,3-4H2,1H3,(H,26,27,30)(H2,25,28,31,32)/b14-6- UBRNYBSDZJHUFR-NSIKDUERSA-N 220052 US9303033, V47, Table 58A, Compound 19 Casein kinase II subunit beta 29314 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220052 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220052&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335357 329995215 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384324 Cc1ccc(cc1F)C(=O)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H18FN7O3/c1-10-2-3-11(6-14(10)22)19(30)27-16-8-17(24-13-4-5-13)29-18(26-16)12(9-23-29)7-15-20(31)28-21(32)25-15/h2-3,6-9,13,24H,4-5H2,1H3,(H,26,27,30)(H2,25,28,31,32)/b15-7- ZWBGIVRPYAFQIC-CHHVJCJISA-N 220053 US9303033, W47, Table 58A, Compound 20 Casein kinase II subunit beta 41784 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220053&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335360 329995216 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384325 COc1ccnc(COc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C19H18N8O4/c1-30-13-4-5-20-12(7-13)9-31-19-24-15-10(6-14-16(28)25-18(29)23-14)8-21-27(15)17(26-19)22-11-2-3-11/h4-8,11H,2-3,9H2,1H3,(H,22,24,26)(H2,23,25,28,29)/b14-6- FCFZPSYAFYOHPF-NSIKDUERSA-N 220055 US9303033, E49, Table 59A, Compound 15::US9303033, Y47, Table 58A, Compound 22 Casein kinase II subunit beta 39441 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220055 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220055&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335497 329995218 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384326 C[C@@H](Oc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccn1 InChI=1S/C19H18N8O3/c1-10(13-4-2-3-7-20-13)30-19-24-15-11(8-14-16(28)25-18(29)23-14)9-21-27(15)17(26-19)22-12-5-6-12/h2-4,7-10,12H,5-6H2,1H3,(H,22,24,26)(H2,23,25,28,29)/b14-8-/t10-/m1/s1 TXZPHCDDLXLASA-DOQDJBIESA-N 220056 US9303033, F49, Table 59A, Compound 16::US9303033, Z47, Table 58A, Compound 23 Casein kinase II subunit beta 28144 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220056 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220056&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335488 329995219 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384327 Clc1ccc(COc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C19H16ClN7O3/c20-12-3-1-10(2-4-12)9-30-19-24-15-11(7-14-16(28)25-18(29)23-14)8-21-27(15)17(26-19)22-13-5-6-13/h1-4,7-8,13H,5-6,9H2,(H,22,24,26)(H2,23,25,28,29)/b14-7- YTWUMEOPIJMKEC-AUWJEWJLSA-N 220057 US9303033, A48, Table 58A, Compound 24::US9303033, G49, Table 59A, Compound 17 Casein kinase II subunit beta 11381 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220057 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220057&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335381 329995220 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384328 CC(C)N1CCN(CC1)c1ccc(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C25H29N9O3/c1-15(2)32-9-11-33(12-10-32)18-5-7-19(8-6-18)37-25-29-21-16(13-20-22(35)30-24(36)28-20)14-26-34(21)23(31-25)27-17-3-4-17/h5-8,13-15,17H,3-4,9-12H2,1-2H3,(H,27,29,31)(H2,28,30,35,36)/b20-13- XXMCDIDYNPVKBF-MOSHPQCFSA-N 219752 US9303033, B48, Table 58A, Compound 25::US9303033, H49, Table 59A, Compound 18::US9303033, K36, Table 39A, Compound 59 Casein kinase II subunit beta 65249 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=219752 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=219752&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335490 329994930 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384329 Nc1cc(Nc2cc(Cl)ccc2F)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C16H11ClFN7O2/c17-8-1-2-9(18)10(4-8)21-13-5-12(19)25-14(23-13)7(6-20-25)3-11-15(26)24-16(27)22-11/h1-6H,19H2,(H,21,23)(H2,22,24,26,27)/b11-3- LGEPKJARNKBUNX-JYOAFUTRSA-N 220059 US9303033, C48, Table 58A, Compound 26::US9303033, I49, Table 59A, Compound 19 Casein kinase II subunit beta 80785 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220059 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220059&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335378 329995221 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384330 COc1c(F)cccc1Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H18FN7O3/c1-31-17-12(21)3-2-4-13(17)24-15-8-16(23-11-5-6-11)28-18(26-15)10(9-22-28)7-14-19(29)27-20(30)25-14/h2-4,7-9,11,23H,5-6H2,1H3,(H,24,26)(H2,25,27,29,30)/b14-7- APWSAWRZKWXPED-AUWJEWJLSA-N 220060 US9303033, D48, Table 58A, Compound 27::US9303033, J49, Table 59A, Compound 20 Casein kinase II subunit beta 47119 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220060 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220060&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336181 329995222 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384331 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(Nc3ccc(cc3)N3CCCCC3)nc12 InChI=1S/C24H26N8O2/c33-23-19(28-24(34)30-23)12-15-14-25-32-21(27-17-4-5-17)13-20(29-22(15)32)26-16-6-8-18(9-7-16)31-10-2-1-3-11-31/h6-9,12-14,17,27H,1-5,10-11H2,(H,26,29)(H2,28,30,33,34)/b19-12- VABIAMOMEHWDTJ-UNOMPAQXSA-N 220061 US9303033, E48, Table 58A, Compound 28 Casein kinase II subunit beta 21326 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220061 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220061&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335377 329995223 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384332 C[C@H](Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1cc(Cl)ccc1F InChI=1S/C21H19ClFN7O2/c1-10(14-7-12(22)2-5-15(14)23)25-17-8-18(26-13-3-4-13)30-19(28-17)11(9-24-30)6-16-20(31)29-21(32)27-16/h2,5-10,13,26H,3-4H2,1H3,(H,25,28)(H2,27,29,31,32)/b16-6-/t10-/m0/s1 NJJIFTBJMGOWPK-KCUAXXGYSA-N 220062 US9303033, F48, Table 58A, Compound 29 Casein kinase II subunit beta 26323 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220062 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220062&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313734 329995224 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384333 Clc1cnc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c(Cl)c1 InChI=1S/C18H14Cl2N8O2/c19-9-4-11(20)15(21-7-9)25-13-5-14(23-10-1-2-10)28-16(26-13)8(6-22-28)3-12-17(29)27-18(30)24-12/h3-7,10,23H,1-2H2,(H,21,25,26)(H2,24,27,29,30)/b12-3- DFXNKHZZJAAAIJ-BASWHVEKSA-N 220064 BDBM220084::US9303033, H48, Table 58A, Compound 31 Casein kinase II subunit beta 36311 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220064&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314640 329995226 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384334 Nc1cc(Nc2cc(Cl)ccc2F)nc2c(\C=C3/CC(=O)NC3=O)cnn12 InChI=1S/C17H12ClFN6O2/c18-10-1-2-11(19)12(5-10)22-14-6-13(20)25-16(23-14)9(7-21-25)3-8-4-15(26)24-17(8)27/h1-3,5-7H,4,20H2,(H,22,23)(H,24,26,27)/b8-3+ JQZXCMCTEKIIGS-FPYGCLRLSA-N 220065 US9303033, I48, Table 58A, Compound 32 Casein kinase II subunit beta 6687 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220065&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314659 329995227 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384335 CC(C)(C)CC(=O)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H23N7O3/c1-19(2,3)8-15(27)23-13-7-14(21-11-4-5-11)26-16(24-13)10(9-20-26)6-12-17(28)25-18(29)22-12/h6-7,9,11,21H,4-5,8H2,1-3H3,(H,23,24,27)(H2,22,25,28,29)/b12-6- HUXMZQUONJTBEH-SDQBBNPISA-N 218880 US9303033, K48, Table 58A, Compound 34::US9303033, L2, Table 7A, Compound 3 Casein kinase II subunit beta 25886 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218880 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218880&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335356 329994103 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384336 FC(F)(F)c1cccc(c1)C(=O)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H16F3N7O3/c22-21(23,24)12-3-1-2-10(6-12)18(32)29-15-8-16(26-13-4-5-13)31-17(28-15)11(9-25-31)7-14-19(33)30-20(34)27-14/h1-3,6-9,13,26H,4-5H2,(H,28,29,32)(H2,27,30,33,34)/b14-7- ATFBLRRPYUJUSX-AUWJEWJLSA-N 220068 US9303033, L48, Table 58A, Compound 35 Casein kinase II subunit beta 12626 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220068 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220068&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336009 329995229 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384337 Fc1ccccc1C(=O)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H16FN7O3/c21-13-4-2-1-3-12(13)18(29)26-15-8-16(23-11-5-6-11)28-17(25-15)10(9-22-28)7-14-19(30)27-20(31)24-14/h1-4,7-9,11,23H,5-6H2,(H,25,26,29)(H2,24,27,30,31)/b14-7- WSRXUPMRXMZWQP-AUWJEWJLSA-N 220069 US9303033, M48, Table 58A, Compound 36 Casein kinase II subunit beta 10818 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220069 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220069&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314283 329995230 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384338 Fc1cc(F)c(F)c(c1)C(=O)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H14F3N7O3/c21-9-4-11(16(23)12(22)5-9)18(31)28-14-6-15(25-10-1-2-10)30-17(27-14)8(7-24-30)3-13-19(32)29-20(33)26-13/h3-7,10,25H,1-2H2,(H,27,28,31)(H2,26,29,32,33)/b13-3- SRBCHFWLSVRQIB-DXNYSGJVSA-N 220070 US9303033, N48, Table 58A, Compound 37 Casein kinase II subunit beta 6252 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220070 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220070&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335731 329995231 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384339 CC(C)(C)OC(=O)N1CCOC(C1)C(=O)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C23H28N8O6/c1-23(2,3)37-22(35)30-6-7-36-15(11-30)20(33)28-16-9-17(25-13-4-5-13)31-18(27-16)12(10-24-31)8-14-19(32)29-21(34)26-14/h8-10,13,15,25H,4-7,11H2,1-3H3,(H,27,28,33)(H2,26,29,32,34)/b14-8- RQHPKLZXGGCKDN-ZSOIEALJSA-N 220071 US9303033, O48, Table 58A, Compound 38 Casein kinase II subunit beta 28649 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220071&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68336166 329995232 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384340 O=C(C1CC1C#N)N1CCN(CC1)c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H23N9O3/c23-10-12-7-15(12)21(33)30-5-3-29(4-6-30)17-9-18(25-14-1-2-14)31-19(27-17)13(11-24-31)8-16-20(32)28-22(34)26-16/h8-9,11-12,14-15,25H,1-7H2,(H2,26,28,32,34)/b16-8- UMCRUETTXKWAEP-PXNMLYILSA-N 220081 US9303033, Y48, Table 59A, Compound 9 Casein kinase II subunit beta 2026 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220081&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313986 329995241 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384341 FC(F)(F)c1cnc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c(Cl)c1 InChI=1S/C19H14ClF3N8O2/c20-11-4-9(19(21,22)23)7-24-15(11)28-13-5-14(26-10-1-2-10)31-16(29-13)8(6-25-31)3-12-17(32)30-18(33)27-12/h3-7,10,26H,1-2H2,(H,24,28,29)(H2,27,30,32,33)/b12-3- RCPTZYLAIZBHNY-BASWHVEKSA-N 220083 US9303033, A49, Table 59A, Compound 11 Casein kinase II subunit beta 87627 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220083 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220083&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315043 329995243 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384342 Clc1cnc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c(Cl)c1 InChI=1S/C18H14Cl2N8O2/c19-9-4-11(20)15(21-7-9)25-13-5-14(23-10-1-2-10)28-16(26-13)8(6-22-28)3-12-17(29)27-18(30)24-12/h3-7,10,23H,1-2H2,(H,21,25,26)(H2,24,27,29,30)/b12-3- DFXNKHZZJAAAIJ-BASWHVEKSA-N 220064 BDBM220084::US9303033, H48, Table 58A, Compound 31 Casein kinase II subunit beta 26245 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220064&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314640 329995226 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384343 C[C@@H](Oc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccn1 InChI=1S/C19H18N8O3/c1-10(13-4-2-3-7-20-13)30-19-24-15-11(8-14-16(28)25-18(29)23-14)9-21-27(15)17(26-19)22-12-5-6-12/h2-4,7-10,12H,5-6H2,1H3,(H,22,24,26)(H2,23,25,28,29)/b14-8-/t10-/m1/s1 TXZPHCDDLXLASA-DOQDJBIESA-N 220056 US9303033, F49, Table 59A, Compound 16::US9303033, Z47, Table 58A, Compound 23 Casein kinase II subunit beta 49170 7 US Patent 10.7270/Q2CN72RX aid1802517 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=220056 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=220056&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335488 329995219 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384344 Nc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12 InChI=1S/C16H12ClN7O2/c17-9-2-1-3-10(5-9)20-13-6-12(18)24-14(22-13)8(7-19-24)4-11-15(25)23-16(26)21-11/h1-7H,18H2,(H,20,22)(H2,21,23,25,26)/b11-4- HNZIQNMBDOAHAU-WCIBSUBMSA-N 218843 US9303033, A1, Example 5 Casein kinase II subunit beta 1177.9 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218843 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218843&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 53240560 329994066 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384345 Clc1cccc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C19H16ClN7O2/c20-11-2-1-3-13(7-11)22-15-8-16(23-12-4-5-12)27-17(25-15)10(9-21-27)6-14-18(28)26-19(29)24-14/h1-3,6-9,12,23H,4-5H2,(H,22,25)(H2,24,26,28,29)/b14-6- JFIDFEQEKNROTB-NSIKDUERSA-N 218845 US9303033, C1, Table 2A, Compound 1 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218845 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218845&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 53240563 329994068 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384346 Fc1cccc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C19H16FN7O2/c20-11-2-1-3-13(7-11)22-15-8-16(23-12-4-5-12)27-17(25-15)10(9-21-27)6-14-18(28)26-19(29)24-14/h1-3,6-9,12,23H,4-5H2,(H,22,25)(H2,24,26,28,29)/b14-6- IPCBMEUQLIRWSA-NSIKDUERSA-N 218846 US9303033, D1, Table 2A, Compound 2 Casein kinase II subunit beta 2200.2 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218846 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218846&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 53240654 329994069 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384347 FC(F)(F)Oc1cccc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C20H16F3N7O3/c21-20(22,23)33-13-3-1-2-12(7-13)25-15-8-16(26-11-4-5-11)30-17(28-15)10(9-24-30)6-14-18(31)29-19(32)27-14/h1-3,6-9,11,26H,4-5H2,(H,25,28)(H2,27,29,31,32)/b14-6- BTJAIBYSVLJCME-NSIKDUERSA-N 218847 US9303033, E1, Table 2A, Compound 3 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218847&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314991 329994070 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384348 COc1cccc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C20H19N7O3/c1-30-14-4-2-3-13(8-14)22-16-9-17(23-12-5-6-12)27-18(25-16)11(10-21-27)7-15-19(28)26-20(29)24-15/h2-4,7-10,12,23H,5-6H2,1H3,(H,22,25)(H2,24,26,28,29)/b15-7- BOPJPRDVSOJKEO-CHHVJCJISA-N 218848 US9303033, F1, Table 2A, Compound 4 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218848 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218848&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68334960 329994071 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384349 CC(N1CC(C)OC(C)C1)c1cccc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C27H32N8O3/c1-15-13-34(14-16(2)38-15)17(3)18-5-4-6-21(9-18)29-23-11-24(30-20-7-8-20)35-25(32-23)19(12-28-35)10-22-26(36)33-27(37)31-22/h4-6,9-12,15-17,20,30H,7-8,13-14H2,1-3H3,(H,29,32)(H2,31,33,36,37)/b22-10- NJSAKNWAULOJDA-YVNNLAQVSA-N 218849 US9303033, G1, Table 4A, Compound 1 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218849 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218849&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68334968 329994072 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384350 FC(F)(F)c1cc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)ccc1Cl InChI=1S/C20H15ClF3N7O2/c21-13-4-3-11(6-12(13)20(22,23)24)26-15-7-16(27-10-1-2-10)31-17(29-15)9(8-25-31)5-14-18(32)30-19(33)28-14/h3-8,10,27H,1-2H2,(H,26,29)(H2,28,30,32,33)/b14-5- UTDYMTRMVYOYIR-RZNTYIFUSA-N 218850 US9303033, H1, Table 4A, Compound 2 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218850 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218850&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335505 329994073 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384351 Clc1ccc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1 InChI=1S/C19H16ClN7O2/c20-11-1-3-12(4-2-11)22-15-8-16(23-13-5-6-13)27-17(25-15)10(9-21-27)7-14-18(28)26-19(29)24-14/h1-4,7-9,13,23H,5-6H2,(H,22,25)(H2,24,26,28,29)/b14-7- AUHBJUZOEOGVGH-AUWJEWJLSA-N 218851 US9303033, I1, Table 4A, Compound 3 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218851&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335598 329994074 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384352 FC(F)(F)c1cccc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C20H16F3N7O2/c21-20(22,23)11-2-1-3-13(7-11)25-15-8-16(26-12-4-5-12)30-17(28-15)10(9-24-30)6-14-18(31)29-19(32)27-14/h1-3,6-9,12,26H,4-5H2,(H,25,28)(H2,27,29,31,32)/b14-6- IUUVGECHVYLVCB-NSIKDUERSA-N 218852 US9303033, J1, Table 4A, Compound 4::US9303033, Z38, Table 43A, Compound 3 Casein kinase II subunit beta 2479.9 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218852&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335111 329994075 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384353 COc1ccc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1Cl InChI=1S/C20H18ClN7O3/c1-31-15-5-4-12(7-13(15)21)23-16-8-17(24-11-2-3-11)28-18(26-16)10(9-22-28)6-14-19(29)27-20(30)25-14/h4-9,11,24H,2-3H2,1H3,(H,23,26)(H2,25,27,29,30)/b14-6- BIRPCVRELQKJSX-NSIKDUERSA-N 218853 US9303033, B39, Table 43A, Compound 5::US9303033, K1, Table 4A, Compound 5 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218853&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68334997 329994076 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384354 Fc1ccc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c(Cl)c1 InChI=1S/C19H15ClFN7O2/c20-12-6-10(21)1-4-13(12)24-15-7-16(23-11-2-3-11)28-17(26-15)9(8-22-28)5-14-18(29)27-19(30)25-14/h1,4-8,11,23H,2-3H2,(H,24,26)(H2,25,27,29,30)/b14-5- PSUYQUFWOBTWBY-RZNTYIFUSA-N 218854 US9303033, D39, Table 43A, Compound 7::US9303033, L1, Table 4A, Compound 6 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218854&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335597 329994077 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384355 CC(C)Oc1cccc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C22H23N7O3/c1-12(2)32-16-5-3-4-15(9-16)24-18-10-19(25-14-6-7-14)29-20(27-18)13(11-23-29)8-17-21(30)28-22(31)26-17/h3-5,8-12,14,25H,6-7H2,1-2H3,(H,24,27)(H2,26,28,30,31)/b17-8- MWRXPVUOFUGJNR-IUXPMGMMSA-N 218855 US9303033, F39, Table 43A, Compound 9::US9303033, M1, Table 4A, Compound 7 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218855&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335722 329994078 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384356 Fc1cc(F)cc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C19H15F2N7O2/c20-10-4-11(21)6-13(5-10)23-15-7-16(24-12-1-2-12)28-17(26-15)9(8-22-28)3-14-18(29)27-19(30)25-14/h3-8,12,24H,1-2H2,(H,23,26)(H2,25,27,29,30)/b14-3- KUHWYPFQFWKCLL-BNNQUZSASA-N 218856 US9303033, N1, Table 4A, Compound 8 Casein kinase II subunit beta 1970.6 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218856 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218856&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314367 329994079 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384357 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(Nc3ccccn3)nc12 InChI=1S/C18H16N8O2/c27-17-12(22-18(28)25-17)7-10-9-20-26-15(21-11-4-5-11)8-14(24-16(10)26)23-13-3-1-2-6-19-13/h1-3,6-9,11,21H,4-5H2,(H,19,23,24)(H2,22,25,27,28)/b12-7- HSWIYUXCTPMBRM-GHXNOFRVSA-N 218857 US9303033, O1, Table 4A, Compound 9 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218857&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335083 329994080 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384358 COc1cccc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1Cl InChI=1S/C20H18ClN7O3/c1-31-14-4-2-3-12(17(14)21)24-15-8-16(23-11-5-6-11)28-18(26-15)10(9-22-28)7-13-19(29)27-20(30)25-13/h2-4,7-9,11,23H,5-6H2,1H3,(H,24,26)(H2,25,27,29,30)/b13-7- WOROEHKEGUNXHA-QPEQYQDCSA-N 218858 US9303033, P1, Table 4A, Compound 10 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218858 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218858&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335600 329994081 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384359 Fc1ccc(Cl)cc1Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H15ClFN7O2/c20-10-1-4-12(21)13(6-10)24-15-7-16(23-11-2-3-11)28-17(26-15)9(8-22-28)5-14-18(29)27-19(30)25-14/h1,4-8,11,23H,2-3H2,(H,24,26)(H2,25,27,29,30)/b14-5- MPLIXQKBZMDAJK-RZNTYIFUSA-N 218859 US9303033, A39, Table 43A, Compound 4::US9303033, Q1, Table 4A, Compound 11 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218859&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313965 329994082 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384360 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(Nc3ccc(cc3)-n3cccn3)nc12 InChI=1S/C22H19N9O2/c32-21-17(27-22(33)29-21)10-13-12-24-31-19(26-15-2-3-15)11-18(28-20(13)31)25-14-4-6-16(7-5-14)30-9-1-8-23-30/h1,4-12,15,26H,2-3H2,(H,25,28)(H2,27,29,32,33)/b17-10- MSAYOPJLIGLEAB-YVLHZVERSA-N 218860 US9303033, C39, Table 43A, Compound 6::US9303033, Example 275, Table 52, Compound 1::US9303033, R1, Table 4A, Compound 12 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218860&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 53240655 329994083 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384361 Fc1ccc(Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1Cl InChI=1S/C19H15ClFN7O2/c20-12-6-11(3-4-13(12)21)23-15-7-16(24-10-1-2-10)28-17(26-15)9(8-22-28)5-14-18(29)27-19(30)25-14/h3-8,10,24H,1-2H2,(H,23,26)(H2,25,27,29,30)/b14-5- HGNZZERUXOSBIR-RZNTYIFUSA-N 218861 US9303033, E39, Table 43A, Compound 8::US9303033, S1, Table 4A, Compound 13 Casein kinase II subunit beta 2041 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218861&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335726 329994084 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384362 Clc1cccc(Nc2cc(NCC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C20H18ClN7O2/c21-13-2-1-3-14(7-13)24-16-8-17(22-9-11-4-5-11)28-18(26-16)12(10-23-28)6-15-19(29)27-20(30)25-15/h1-3,6-8,10-11,22H,4-5,9H2,(H,24,26)(H2,25,27,29,30)/b15-6- BFYIETOTLUQMJQ-UUASQNMZSA-N 218862 US9303033, T1, Table 6A, Compound 1 Casein kinase II subunit beta 508.7 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218862&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335601 329994085 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384363 CCOC(=O)c1cc(F)cc(Nc2cc(NCC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C23H22FN7O4/c1-2-35-22(33)13-5-15(24)8-16(6-13)27-18-9-19(25-10-12-3-4-12)31-20(29-18)14(11-26-31)7-17-21(32)30-23(34)28-17/h5-9,11-12,25H,2-4,10H2,1H3,(H,27,29)(H2,28,30,32,34)/b17-7- LTHNDYXDEKHMOS-IDUWFGFVSA-N 218863 US9303033, U1, Table 6A, Compound 2 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218863&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335730 329994086 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384364 O=C1NC(=O)\C(N1)=C\c1cnn2c(NCC3CC3)cc(Nc3cccnc3)nc12 InChI=1S/C19H18N8O2/c28-18-14(24-19(29)26-18)6-12-9-22-27-16(21-8-11-3-4-11)7-15(25-17(12)27)23-13-2-1-5-20-10-13/h1-2,5-7,9-11,21H,3-4,8H2,(H,23,25)(H2,24,26,28,29)/b14-6- CZTDEVWNTYEOEH-NSIKDUERSA-N 218864 US9303033, V1, Table 6A, Compound 3 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218864&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335732 329994087 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384365 Cc1ccc(Nc2cc(NCC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)nc1 InChI=1S/C20H20N8O2/c1-11-2-5-15(21-8-11)25-16-7-17(22-9-12-3-4-12)28-18(26-16)13(10-23-28)6-14-19(29)27-20(30)24-14/h2,5-8,10,12,22H,3-4,9H2,1H3,(H,21,25,26)(H2,24,27,29,30)/b14-6- UHQNZOMCFVHEPN-NSIKDUERSA-N 218865 US9303033, W1, Table 6A, Compound 4 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218865&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335814 329994088 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384366 Clc1ccc(Nc2cc(NCC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cn1 InChI=1S/C19H17ClN8O2/c20-14-4-3-12(9-21-14)24-15-6-16(22-7-10-1-2-10)28-17(26-15)11(8-23-28)5-13-18(29)27-19(30)25-13/h3-6,8-10,22H,1-2,7H2,(H,24,26)(H2,25,27,29,30)/b13-5- PRJTVGRLGCNUTI-ACAGNQJTSA-N 218866 US9303033, X1, Table 6A, Compound 5 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218866&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 88941166 329994089 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384367 CC(=O)Nc1cccc(Nc2cc(NCC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1 InChI=1S/C22H22N8O3/c1-12(31)25-15-3-2-4-16(8-15)26-18-9-19(23-10-13-5-6-13)30-20(28-18)14(11-24-30)7-17-21(32)29-22(33)27-17/h2-4,7-9,11,13,23H,5-6,10H2,1H3,(H,25,31)(H,26,28)(H2,27,29,32,33)/b17-7- IHMGHVQNRLYZDW-IDUWFGFVSA-N 218867 US9303033, Y1, Table 6A, Compound 6 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218867&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68334981 329994090 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384368 Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C13H13N7O2/c14-9-4-10(16-7-1-2-7)20-11(18-9)6(5-15-20)3-8-12(21)19-13(22)17-8/h3-5,7,16H,1-2H2,(H2,14,18)(H2,17,19,21,22)/b8-3- NUJZHVVLHDDEAQ-BAQGIRSFSA-N 218878 US9303033, J2, Table 7A, Compound 1 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218878 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218878&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314476 329994101 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384369 O=C(Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C1CC1 InChI=1S/C17H17N7O3/c25-15(8-1-2-8)22-12-6-13(19-10-3-4-10)24-14(21-12)9(7-18-24)5-11-16(26)23-17(27)20-11/h5-8,10,19H,1-4H2,(H,21,22,25)(H2,20,23,26,27)/b11-5- UBYVOQDIVWWYHS-WZUFQYTHSA-N 218879 US9303033, K2, Table 7A, Compound 2 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218879 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218879&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315141 329994102 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384370 FC1(F)CCN(CC1)c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H19F2N7O2/c19-18(20)3-5-26(6-4-18)13-8-14(22-11-1-2-11)27-15(24-13)10(9-21-27)7-12-16(28)25-17(29)23-12/h7-9,11,22H,1-6H2,(H2,23,25,28,29)/b12-7- SZOBWMZGRHTRNG-GHXNOFRVSA-N 218881 US9303033, M2, Example 25 Casein kinase II subunit beta 359 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218881 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218881&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313789 329994104 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384371 O=Cc1cnn2c(NC3CC3)cc(NC3CCCC3)nc12 InChI=1S/C15H19N5O/c21-9-10-8-16-20-14(18-12-5-6-12)7-13(19-15(10)20)17-11-3-1-2-4-11/h7-9,11-12,18H,1-6H2,(H,17,19) YMLFRUATSMBCCP-UHFFFAOYSA-N 218882 US9303033, N2, Example 26 Casein kinase II subunit beta 845.3 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218882 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218882&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314303 329994105 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384372 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(NC3CCCC3)nc12 InChI=1S/C18H21N7O2/c26-17-13(22-18(27)24-17)7-10-9-19-25-15(21-12-5-6-12)8-14(23-16(10)25)20-11-3-1-2-4-11/h7-9,11-12,21H,1-6H2,(H,20,23)(H2,22,24,26,27)/b13-7- NBQJLSZPMCVDJI-QPEQYQDCSA-N 218883 US9303033, O2, Example 27 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218883 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218883&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67252472 329994106 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384373 F[C@@H]1CCN(C1)c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C17H18FN7O2/c18-10-3-4-24(8-10)13-6-14(20-11-1-2-11)25-15(22-13)9(7-19-25)5-12-16(26)23-17(27)21-12/h5-7,10-11,20H,1-4,8H2,(H2,21,23,26,27)/b12-5-/t10-/m1/s1 WYQRMIAXGHCXIP-CGYDICSFSA-N 218884 US9303033, P2, Table 9A, Compound 1 Casein kinase II subunit beta 707.6 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218884&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68334993 329994107 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384374 O=C1NC(=O)\C(N1)=C\c1cnn2c(NCC3CC3)cc(NN3CCOCC3)nc12 InChI=1S/C18H22N8O3/c27-17-13(21-18(28)23-17)7-12-10-20-26-15(19-9-11-1-2-11)8-14(22-16(12)26)24-25-3-5-29-6-4-25/h7-8,10-11,19H,1-6,9H2,(H,22,24)(H2,21,23,27,28)/b13-7- TWQKOGWPLWPDDD-QPEQYQDCSA-N 218885 US9303033, Q2, Table 9A, Compound 2 Casein kinase II subunit beta 284.1 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218885&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335755 329994108 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384375 N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H24N8O2/c20-11-1-3-12(4-2-11)22-15-8-16(23-13-5-6-13)27-17(25-15)10(9-21-27)7-14-18(28)26-19(29)24-14/h7-9,11-13,23H,1-6,20H2,(H,22,25)(H2,24,26,28,29)/b14-7-/t11-,12- BFKWWMRDPZCHKV-URQBRDCWSA-N 218886 US9303033, O36, Table 41A, Compound 1::US9303033, R2, Table 9A, Compound 3 Casein kinase II subunit beta 878.3 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218886 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218886&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67253135 329994109 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384376 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(NN3CCOCC3)nc12 InChI=1S/C17H20N8O3/c26-16-12(20-17(27)22-16)7-10-9-18-25-14(19-11-1-2-11)8-13(21-15(10)25)23-24-3-5-28-6-4-24/h7-9,11,19H,1-6H2,(H,21,23)(H2,20,22,26,27)/b12-7- NUJUZGJOAHAYFW-GHXNOFRVSA-N 218887 US9303033, S2, Table 9A, Compound 4 Casein kinase II subunit beta 1298.4 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218887 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218887&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68334986 329994110 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384377 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(NCC3CC3)nc12 InChI=1S/C17H19N7O2/c25-16-12(21-17(26)23-16)5-10-8-19-24-14(20-11-3-4-11)6-13(22-15(10)24)18-7-9-1-2-9/h5-6,8-9,11,20H,1-4,7H2,(H,18,22)(H2,21,23,25,26)/b12-5- OIROTWLDYCLPOT-XGICHPGQSA-N 218888 US9303033, T2, Table 9A, Compound 5 Casein kinase II subunit beta 997.8 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218888&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335610 329994111 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384378 C[C@H](Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C1CC1 InChI=1S/C18H21N7O2/c1-9(10-2-3-10)20-14-7-15(21-12-4-5-12)25-16(23-14)11(8-19-25)6-13-17(26)24-18(27)22-13/h6-10,12,21H,2-5H2,1H3,(H,20,23)(H2,22,24,26,27)/b13-6-/t9-/m0/s1 ISOROGJOHADWEE-FVNYMESBSA-N 218889 US9303033, U2, Table 9A, Compound 6 Casein kinase II subunit beta 765.9 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218889 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218889&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335760 329994112 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384379 CN1CCC(CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H24N8O2/c1-26-6-4-13(5-7-26)21-15-9-16(22-12-2-3-12)27-17(24-15)11(10-20-27)8-14-18(28)25-19(29)23-14/h8-10,12-13,22H,2-7H2,1H3,(H,21,24)(H2,23,25,28,29)/b14-8- BESZLGFYFGJYDA-ZSOIEALJSA-N 218890 US9303033, V2, Table 9A, Compound 7 Casein kinase II subunit beta 1365.2 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218890&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335513 329994113 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384380 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(NC3CCNCC3)nc12 InChI=1S/C18H22N8O2/c27-17-13(23-18(28)25-17)7-10-9-20-26-15(22-11-1-2-11)8-14(24-16(10)26)21-12-3-5-19-6-4-12/h7-9,11-12,19,22H,1-6H2,(H,21,24)(H2,23,25,27,28)/b13-7- QXMGXTIJONVBND-QPEQYQDCSA-N 218891 US9303033, W2, Table 9A, Compound 8 Casein kinase II subunit beta 877.1 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218891 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218891&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335514 329994114 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384381 C[C@@H](Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)C1CC1 InChI=1S/C18H21N7O2/c1-9(10-2-3-10)20-14-7-15(21-12-4-5-12)25-16(23-14)11(8-19-25)6-13-17(26)24-18(27)22-13/h6-10,12,21H,2-5H2,1H3,(H,20,23)(H2,22,24,26,27)/b13-6-/t9-/m1/s1 ISOROGJOHADWEE-JHFYRWCBSA-N 218892 US9303033, Q45, Table 50A, Compound 74::US9303033, X2, Table 9A, Compound 9 Casein kinase II subunit beta 1952 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218892 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218892&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335079 329994115 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384382 CC(=O)N[C@H]1CCC(CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H26N8O3/c1-11(30)23-13-2-4-14(5-3-13)24-17-9-18(25-15-6-7-15)29-19(27-17)12(10-22-29)8-16-20(31)28-21(32)26-16/h8-10,13-15,25H,2-7H2,1H3,(H,23,30)(H,24,27)(H2,26,28,31,32)/b16-8-/t13-,14? KOWNENOOSKDGQV-QBUKKXEESA-N 218893 US9303033, A3, Table 10A, Compound 1::US9303033, D3, Table 10A, Compound 4::US9303033, P36, Table 41A, Compound 2 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218893 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218893&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67256299 329994116 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384383 CN(C)C(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H29N9O3/c1-30(2)22(34)26-15-7-3-13(4-8-15)24-17-10-18(25-14-5-6-14)31-19(28-17)12(11-23-31)9-16-20(32)29-21(33)27-16/h9-11,13-15,25H,3-8H2,1-2H3,(H,24,28)(H,26,34)(H2,27,29,32,33)/b16-9-/t13-,15- QQEUIJMSNYEALQ-AAMARJQVSA-N 218894 US9303033, B3, Table 10A, Compound 2 Casein kinase II subunit beta 538.5 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218894 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218894&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67253200 329994117 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384384 COC(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H26N8O4/c1-33-21(32)25-14-6-2-12(3-7-14)23-16-9-17(24-13-4-5-13)29-18(27-16)11(10-22-29)8-15-19(30)28-20(31)26-15/h8-10,12-14,24H,2-7H2,1H3,(H,23,27)(H,25,32)(H2,26,28,30,31)/b15-8-/t12-,14- DJXAOVVHHRACPC-WLOSUKBJSA-N 218895 US9303033, C3, Table 10A, Compound 3::US9303033, S36, Table 41A, Compound 5 Casein kinase II subunit beta 679.1 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218895 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218895&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335515 329994118 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384385 CC(=O)N[C@H]1CCC(CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H26N8O3/c1-11(30)23-13-2-4-14(5-3-13)24-17-9-18(25-15-6-7-15)29-19(27-17)12(10-22-29)8-16-20(31)28-21(32)26-16/h8-10,13-15,25H,2-7H2,1H3,(H,23,30)(H,24,27)(H2,26,28,31,32)/b16-8-/t13-,14? KOWNENOOSKDGQV-QBUKKXEESA-N 218893 US9303033, A3, Table 10A, Compound 1::US9303033, D3, Table 10A, Compound 4::US9303033, P36, Table 41A, Compound 2 Casein kinase II subunit beta 476 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218893 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218893&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67256299 329994116 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384386 CS(=O)(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H26N8O4S/c1-33(31,32)27-14-6-4-12(5-7-14)22-16-9-17(23-13-2-3-13)28-18(25-16)11(10-21-28)8-15-19(29)26-20(30)24-15/h8-10,12-14,23,27H,2-7H2,1H3,(H,22,25)(H2,24,26,29,30)/b15-8-/t12-,14- YQNATXAICQCDQY-WLOSUKBJSA-N 218897 US9303033, E3, Table 10A, Compound 5::US9303033, R36, Table 41A, Compound 4 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218897 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218897&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335828 329994119 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384387 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(SCc3ccccc3)nc12 InChI=1S/C20H18N6O2S/c27-19-15(23-20(28)25-19)8-13-10-21-26-16(22-14-6-7-14)9-17(24-18(13)26)29-11-12-4-2-1-3-5-12/h1-5,8-10,14,22H,6-7,11H2,(H2,23,25,27,28)/b15-8- HKVGQMZATWPSMH-NVNXTCNLSA-N 218898 US9303033, Example 33, Table 11, Compound 1 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218898 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218898&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314318 329994120 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384388 CC(C)CNc1cc(NC2CC2)n2ncc(\C=C3/SC(=O)NC3=O)c2n1 InChI=1S/C17H20N6O2S/c1-9(2)7-18-13-6-14(20-11-3-4-11)23-15(21-13)10(8-19-23)5-12-16(24)22-17(25)26-12/h5-6,8-9,11,20H,3-4,7H2,1-2H3,(H,18,21)(H,22,24,25)/b12-5- CERNOHHTNQVWNF-XGICHPGQSA-N 218899 US9303033, F3, Table 12A, Compound 1 Casein kinase II subunit beta 1643.8 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218899 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218899&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313752 329994121 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384389 CCN1CCCC1CNc1cc(NC2CC2)n2ncc(\C=C3/SC(=O)NC3=O)c2n1 InChI=1S/C20H25N7O2S/c1-2-26-7-3-4-14(26)11-21-16-9-17(23-13-5-6-13)27-18(24-16)12(10-22-27)8-15-19(28)25-20(29)30-15/h8-10,13-14,23H,2-7,11H2,1H3,(H,21,24)(H,25,28,29)/b15-8- FAQOWDYZKXSJDW-NVNXTCNLSA-N 218900 US9303033, G3, Table 12A, Compound 2 Casein kinase II subunit beta 1845.6 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218900 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218900&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315022 329994122 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384390 CC(O)CNc1cc(NC2CC2)n2ncc(\C=C3/SC(=O)NC3=O)c2n1 InChI=1S/C16H18N6O3S/c1-8(23)6-17-12-5-13(19-10-2-3-10)22-14(20-12)9(7-18-22)4-11-15(24)21-16(25)26-11/h4-5,7-8,10,19,23H,2-3,6H2,1H3,(H,17,20)(H,21,24,25)/b11-4- NAMKQURFKKDWSF-WCIBSUBMSA-N 218901 US9303033, H3, Table 12A, Compound 3 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218901 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218901&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314397 329994123 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384391 CN(C)c1cc(NC2CC2)n2ncc(\C=C3/SC(=O)NC3=O)c2n1 InChI=1S/C15H16N6O2S/c1-20(2)11-6-12(17-9-3-4-9)21-13(18-11)8(7-16-21)5-10-14(22)19-15(23)24-10/h5-7,9,17H,3-4H2,1-2H3,(H,19,22,23)/b10-5- MYRPEVBCFHHODE-YHYXMXQVSA-N 218902 US9303033, I3, Table 12A, Compound 4 Casein kinase II subunit beta 875.9 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218902 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218902&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313856 329994124 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384392 Clc1cccc(Nc2cc(NC3CC3)n3ncc(\C=C4/SC(=O)NC4=O)c3n2)c1 InChI=1S/C19H15ClN6O2S/c20-11-2-1-3-13(7-11)22-15-8-16(23-12-4-5-12)26-17(24-15)10(9-21-26)6-14-18(27)25-19(28)29-14/h1-3,6-9,12,23H,4-5H2,(H,22,24)(H,25,27,28)/b14-6- OQCGIQIYJLJGFM-NSIKDUERSA-N 218903 US9303033, J3, Table 12A, Compound 5 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218903 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218903&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314041 329994125 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384393 O=C1NC(=O)\C(S1)=C\c1cnn2c(NC3CC3)cc(nc12)N1CCOCC1 InChI=1S/C17H18N6O3S/c24-16-12(27-17(25)21-16)7-10-9-18-23-14(19-11-1-2-11)8-13(20-15(10)23)22-3-5-26-6-4-22/h7-9,11,19H,1-6H2,(H,21,24,25)/b12-7- IWXYYNAAQZFOCB-GHXNOFRVSA-N 218904 US9303033, K3, Table 12A, Compound 6 Casein kinase II subunit beta 1393.4 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218904 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218904&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314715 329994126 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384394 CCN(CC)c1cc(NC2CC2)n2ncc(\C=C3/SC(=O)NC3=O)c2n1 InChI=1S/C17H20N6O2S/c1-3-22(4-2)13-8-14(19-11-5-6-11)23-15(20-13)10(9-18-23)7-12-16(24)21-17(25)26-12/h7-9,11,19H,3-6H2,1-2H3,(H,21,24,25)/b12-7- ADPHKYSCOAMTIB-GHXNOFRVSA-N 218905 US9303033, L3, Table 12A, Compound 7 Casein kinase II subunit beta 1432.7 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218905 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218905&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313840 329994127 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384395 CN(C1CCN(C)C1)c1cc(NC2CC2)n2ncc(\C=C3/SC(=O)NC3=O)c2n1 InChI=1S/C19H23N7O2S/c1-24-6-5-13(10-24)25(2)15-8-16(21-12-3-4-12)26-17(22-15)11(9-20-26)7-14-18(27)23-19(28)29-14/h7-9,12-13,21H,3-6,10H2,1-2H3,(H,23,27,28)/b14-7- GHSYEUMFGDGCIY-AUWJEWJLSA-N 218906 US9303033, M3, Table 12A, Compound 8 Casein kinase II subunit beta 1437.9 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218906 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218906&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314045 329994128 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384396 FCCNc1cc(NC2CC2)n2ncc(\C=C3/SC(=O)NC3=O)c2n1 InChI=1S/C15H15FN6O2S/c16-3-4-17-11-6-12(19-9-1-2-9)22-13(20-11)8(7-18-22)5-10-14(23)21-15(24)25-10/h5-7,9,19H,1-4H2,(H,17,20)(H,21,23,24)/b10-5- UXANIPGYPUMQLK-YHYXMXQVSA-N 218907 US9303033, N3, Table 12A, Compound 9 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218907&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58313811 329994129 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384397 CCN(CC)CCNc1cc(NC2CC2)n2ncc(\C=C3/SC(=O)NC3=O)c2n1 InChI=1S/C19H25N7O2S/c1-3-25(4-2)8-7-20-15-10-16(22-13-5-6-13)26-17(23-15)12(11-21-26)9-14-18(27)24-19(28)29-14/h9-11,13,22H,3-8H2,1-2H3,(H,20,23)(H,24,27,28)/b14-9- NZZLFLVZTNYMHW-ZROIWOOFSA-N 218908 US9303033, O3, Table 12A, Compound 10 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218908 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218908&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 53240859 329994130 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384398 CN1C(=O)S\C(=C/c2cnn3c(NC4CC4)cc(Nc4cccc(Cl)c4)nc23)C1=O InChI=1S/C20H17ClN6O2S/c1-26-19(28)15(30-20(26)29)7-11-10-22-27-17(24-13-5-6-13)9-16(25-18(11)27)23-14-4-2-3-12(21)8-14/h2-4,7-10,13,24H,5-6H2,1H3,(H,23,25)/b15-7- KLCOGJOUUQJTDZ-CHHVJCJISA-N 218909 US9303033, P3, Table 12A, Compound 11 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218909 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218909&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314133 329994131 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384399 CN1CCCN(CC1)c1cc(NC2CC2)n2ncc(\C=C3/SC(=O)NC3=O)c2n1 InChI=1S/C19H23N7O2S/c1-24-5-2-6-25(8-7-24)15-10-16(21-13-3-4-13)26-17(22-15)12(11-20-26)9-14-18(27)23-19(28)29-14/h9-11,13,21H,2-8H2,1H3,(H,23,27,28)/b14-9- WFDPANBYIQXCNR-ZROIWOOFSA-N 218910 US9303033, Q3, Table 12A, Compound 12 Casein kinase II subunit beta 2046.1 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218910 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218910&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 53240858 329994132 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384400 O=C1NC(=O)\C(S1)=C\c1cnn2c(NC3CC3)cc(nc12)N1CCN(CC1)c1ccccn1 InChI=1S/C22H22N8O2S/c31-21-16(33-22(32)27-21)11-14-13-24-30-19(25-15-4-5-15)12-18(26-20(14)30)29-9-7-28(8-10-29)17-3-1-2-6-23-17/h1-3,6,11-13,15,25H,4-5,7-10H2,(H,27,31,32)/b16-11- YLJSJPVEHUBDGL-WJDWOHSUSA-N 218911 US9303033, R3, Table 12A, Compound 13 Casein kinase II subunit beta 1820 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218911 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218911&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 53240860 329994133 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384401 Oc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H16N6O3/c26-13-3-1-2-10(6-13)14-8-16(21-12-4-5-12)25-17(22-14)11(9-20-25)7-15-18(27)24-19(28)23-15/h1-3,6-9,12,21,26H,4-5H2,(H2,23,24,27,28)/b15-7- LHKXGWCPNBKTJF-CHHVJCJISA-N 218912 US9303033, G7, Table 22A, Compound 1::US9303033, S3, Table 13A, Compound 1 Casein kinase II subunit beta 613.5 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218912 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218912&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 69940306 329994134 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384402 FC(F)(F)Oc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H15F3N6O3/c21-20(22,23)32-13-3-1-2-10(6-13)14-8-16(25-12-4-5-12)29-17(26-14)11(9-24-29)7-15-18(30)28-19(31)27-15/h1-3,6-9,12,25H,4-5H2,(H2,27,28,30,31)/b15-7- NNYBSRTZNHMIIX-CHHVJCJISA-N 218913 US9303033, H7, Table 22A, Compound 2::US9303033, T3, Table 13A, Compound 2 Casein kinase II subunit beta 890.8 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218913 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218913&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 69940617 329994135 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384403 NC(=O)c1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H17N7O3/c21-17(28)11-3-1-2-10(6-11)14-8-16(23-13-4-5-13)27-18(24-14)12(9-22-27)7-15-19(29)26-20(30)25-15/h1-3,6-9,13,23H,4-5H2,(H2,21,28)(H2,25,26,29,30)/b15-7- OEJVZJDCQDIZGA-CHHVJCJISA-N 218914 US9303033, U3, Table 13A, Compound 3::US9303033, Z7, Table 22A, Compound 20 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218914&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335018 329994136 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384404 OCc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H18N6O3/c27-10-11-2-1-3-12(6-11)15-8-17(22-14-4-5-14)26-18(23-15)13(9-21-26)7-16-19(28)25-20(29)24-16/h1-3,6-9,14,22,27H,4-5,10H2,(H2,24,25,28,29)/b16-7- XDJDNFVTLAZCED-APSNUPSMSA-N 218915 US9303033, A8, Table 22A, Compound 21::US9303033, V3, Table 13A, Compound 4 Casein kinase II subunit beta 649.2 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218915 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218915&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 69939970 329994137 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384405 COC(=O)c1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H18N6O4/c1-31-20(29)12-4-2-3-11(7-12)15-9-17(23-14-5-6-14)27-18(24-15)13(10-22-27)8-16-19(28)26-21(30)25-16/h2-4,7-10,14,23H,5-6H2,1H3,(H2,25,26,28,30)/b16-8- HVPPFXPMHYLOKC-PXNMLYILSA-N 218916 US9303033, I7, Table 22A, Compound 3::US9303033, W3, Table 13A, Compound 5 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218916 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218916&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 69939738 329994138 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384406 CS(=O)(=O)c1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H18N6O4S/c1-31(29,30)14-4-2-3-11(7-14)15-9-17(22-13-5-6-13)26-18(23-15)12(10-21-26)8-16-19(27)25-20(28)24-16/h2-4,7-10,13,22H,5-6H2,1H3,(H2,24,25,27,28)/b16-8- LYSQLMKWDVAPMI-PXNMLYILSA-N 218917 US9303033, J7, Table 22A, Compound 4::US9303033, X3, Table 13A, Compound 6 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218917&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 69940147 329994139 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384407 CNS(=O)(=O)c1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H19N7O4S/c1-21-32(30,31)14-4-2-3-11(7-14)15-9-17(23-13-5-6-13)27-18(24-15)12(10-22-27)8-16-19(28)26-20(29)25-16/h2-4,7-10,13,21,23H,5-6H2,1H3,(H2,25,26,28,29)/b16-8- ACVJJCQOPQXKOF-PXNMLYILSA-N 218918 US9303033, K7, Table 22A, Compound 5::US9303033, Y3, Table 13A, Compound 7 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218918&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67253335 329994140 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384408 CN(C)CCCOc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C24H27N7O3/c1-30(2)9-4-10-34-18-6-3-5-15(11-18)19-13-21(26-17-7-8-17)31-22(27-19)16(14-25-31)12-20-23(32)29-24(33)28-20/h3,5-6,11-14,17,26H,4,7-10H2,1-2H3,(H2,28,29,32,33)/b20-12- XYHIAKXKQJOMIP-NDENLUEZSA-N 218919 US9303033, L7, Table 22A, Compound 6::US9303033, Z3, Table 13A, Compound 8 Casein kinase II subunit beta 2214.4 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218919 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218919&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335014 329994141 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384409 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(nc12)-c1cccc(OCCN2CCOCC2)c1 InChI=1S/C25H27N7O4/c33-24-21(29-25(34)30-24)13-17-15-26-32-22(27-18-4-5-18)14-20(28-23(17)32)16-2-1-3-19(12-16)36-11-8-31-6-9-35-10-7-31/h1-3,12-15,18,27H,4-11H2,(H2,29,30,33,34)/b21-13- UVWPUNVBYWZTEH-BKUYFWCQSA-N 218920 US9303033, A4, Table 13A, Compound 9::US9303033, M7, Table 22A, Compound 7 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218920&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335016 329994142 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384410 OCCCOc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H22N6O4/c29-7-2-8-32-16-4-1-3-13(9-16)17-11-19(24-15-5-6-15)28-20(25-17)14(12-23-28)10-18-21(30)27-22(31)26-18/h1,3-4,9-12,15,24,29H,2,5-8H2,(H2,26,27,30,31)/b18-10- TXBFPRVTKAITKV-ZDLGFXPLSA-N 218921 US9303033, B4, Table 13A, Compound 10::US9303033, B8, Table 22A, Compound 22 Casein kinase II subunit beta 2168.5 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218921 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218921&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335117 329994143 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384411 CS(=O)(=O)Nc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H19N7O4S/c1-32(30,31)26-14-4-2-3-11(7-14)15-9-17(22-13-5-6-13)27-18(23-15)12(10-21-27)8-16-19(28)25-20(29)24-16/h2-4,7-10,13,22,26H,5-6H2,1H3,(H2,24,25,28,29)/b16-8- XJGIBEVYLAJXHY-PXNMLYILSA-N 218922 US9303033, C4, Table 13A, Compound 11::US9303033, C8, Table 22A, Compound 23 Casein kinase II subunit beta 2403.2 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218922 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218922&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67254249 329994144 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384412 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(nc12)-c1cccc(c1)C#N InChI=1S/C20H15N7O2/c21-9-11-2-1-3-12(6-11)15-8-17(23-14-4-5-14)27-18(24-15)13(10-22-27)7-16-19(28)26-20(29)25-16/h1-3,6-8,10,14,23H,4-5H2,(H2,25,26,28,29)/b16-7- ZDDJUFMUPQETHV-APSNUPSMSA-N 218923 US9303033, D4, Table 13A, Compound 12::US9303033, D8, Table 22A, Compound 24 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218923 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218923&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 67253406 329994145 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384413 C=CCOc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C22H20N6O3/c1-2-8-31-16-5-3-4-13(9-16)17-11-19(24-15-6-7-15)28-20(25-17)14(12-23-28)10-18-21(29)27-22(30)26-18/h2-5,9-12,15,24H,1,6-8H2,(H2,26,27,29,30)/b18-10- GQYRYCFHJUAKOP-ZDLGFXPLSA-N 218924 US9303033, E4, Table 13A, Compound 13::US9303033, E8, Table 22A, Compound 25 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218924&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335547 329994146 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384414 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(nc12)-c1cccc(OCC2CC2)c1 InChI=1S/C23H22N6O3/c30-22-19(27-23(31)28-22)9-15-11-24-29-20(25-16-6-7-16)10-18(26-21(15)29)14-2-1-3-17(8-14)32-12-13-4-5-13/h1-3,8-11,13,16,25H,4-7,12H2,(H2,27,28,30,31)/b19-9- ILQVTSAQOCHIRH-OCKHKDLRSA-N 218925 US9303033, F4, Table 13A, Compound 14::US9303033, F8, Table 22A, Compound 26 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218925 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218925&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335049 329994147 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384415 Cc1cc(COc2cccc(c2)-c2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)no1 InChI=1S/C24H21N7O4/c1-13-7-17(30-35-13)12-34-18-4-2-3-14(8-18)19-10-21(26-16-5-6-16)31-22(27-19)15(11-25-31)9-20-23(32)29-24(33)28-20/h2-4,7-11,16,26H,5-6,12H2,1H3,(H2,28,29,32,33)/b20-9- UXWXYJUNIQAEIC-UKWGHVSLSA-N 218926 US9303033, G4, Table 13A, Compound 15::US9303033, N7, Table 22A, Compound 8 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218926 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218926&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335859 329994148 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384416 O=C(COc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)N1CCCC1 InChI=1S/C25H25N7O4/c33-22(31-8-1-2-9-31)14-36-18-5-3-4-15(10-18)19-12-21(27-17-6-7-17)32-23(28-19)16(13-26-32)11-20-24(34)30-25(35)29-20/h3-5,10-13,17,27H,1-2,6-9,14H2,(H2,29,30,34,35)/b20-11- WHEWGZZABMFCDD-JAIQZWGSSA-N 218927 US9303033, H4, Table 13A, Compound 16::US9303033, O7, Table 22A, Compound 9 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218927 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218927&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335256 329994149 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384417 CN1CCN(Cc2cccc(c2)-c2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)CC1 InChI=1S/C25H28N8O2/c1-31-7-9-32(10-8-31)15-16-3-2-4-17(11-16)20-13-22(27-19-5-6-19)33-23(28-20)18(14-26-33)12-21-24(34)30-25(35)29-21/h2-4,11-14,19,27H,5-10,15H2,1H3,(H2,29,30,34,35)/b21-12- NASXYRSFUJAXCS-MTJSOVHGSA-N 218928 US9303033, I4, Table 13A, Compound 17::US9303033, P7, Table 22A, Compound 10 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218928 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218928&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314157 329994150 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384418 CN(C)c1ccc(cc1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C21H21N7O2/c1-27(2)15-7-3-12(4-8-15)16-10-18(23-14-5-6-14)28-19(24-16)13(11-22-28)9-17-20(29)26-21(30)25-17/h3-4,7-11,14,23H,5-6H2,1-2H3,(H2,25,26,29,30)/b17-9- UXBZGXCXOAYKLC-MFOYZWKCSA-N 218929 US9303033, J4, Table 13A, Compound 18::US9303033, Q7, Table 22A, Compound 11 Casein kinase II subunit beta 867 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218929 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218929&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 69940163 329994151 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384419 Fc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H15FN6O2/c20-12-3-1-2-10(6-12)14-8-16(22-13-4-5-13)26-17(23-14)11(9-21-26)7-15-18(27)25-19(28)24-15/h1-3,6-9,13,22H,4-5H2,(H2,24,25,27,28)/b15-7- QOLYMTWFVJPYPN-CHHVJCJISA-N 218930 US9303033, K4, Table 13A, Compound 19::US9303033, R7, Table 22A, Compound 12 Casein kinase II subunit beta 1308.2 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218930 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218930&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 69940082 329994152 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384420 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(nc12)-c1cccc(OCC2=NCCN2)c1 InChI=1S/C23H22N8O3/c32-22-18(29-23(33)30-22)9-14-11-26-31-20(27-15-4-5-15)10-17(28-21(14)31)13-2-1-3-16(8-13)34-12-19-24-6-7-25-19/h1-3,8-11,15,27H,4-7,12H2,(H,24,25)(H2,29,30,32,33)/b18-9- HRDNKNMDOIXOCX-NVMNQCDNSA-N 218931 US9303033, G8, Table 22A, Compound 27::US9303033, L4, Table 13A, Compound 20 Casein kinase II subunit beta 1474.8 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218931 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218931&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335113 329994153 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384421 Oc1ccc(cc1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C19H16N6O3/c26-13-5-1-10(2-6-13)14-8-16(21-12-3-4-12)25-17(22-14)11(9-20-25)7-15-18(27)24-19(28)23-15/h1-2,5-9,12,21,26H,3-4H2,(H2,23,24,27,28)/b15-7- QGEGZWRMRSYNPW-CHHVJCJISA-N 218932 US9303033, H8, Table 22A, Compound 28::US9303033, M4, Table 13A, Compound 21 Casein kinase II subunit beta 1249.7 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218932 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218932&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58314143 329994154 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384422 O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(nc12)-c1cccc(CN2CCOCC2)c1 InChI=1S/C24H25N7O3/c32-23-20(28-24(33)29-23)11-17-13-25-31-21(26-18-4-5-18)12-19(27-22(17)31)16-3-1-2-15(10-16)14-30-6-8-34-9-7-30/h1-3,10-13,18,26H,4-9,14H2,(H2,28,29,32,33)/b20-11- GFDSSUVFRVZXDV-JAIQZWGSSA-N 218933 US9303033, I8, Table 22A, Compound 29::US9303033, N4, Table 13A, Compound 22 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218933 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218933&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 58315024 329994155 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384423 FC(F)(F)c1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H15F3N6O2/c21-20(22,23)12-3-1-2-10(6-12)14-8-16(25-13-4-5-13)29-17(26-14)11(9-24-29)7-15-18(30)28-19(31)27-15/h1-3,6-9,13,25H,4-5H2,(H2,27,28,30,31)/b15-7- UYTCCVYCCVAMRJ-CHHVJCJISA-N 218934 US9303033, J8, Table 22A, Compound 30::US9303033, O4, Table 13A, Compound 23 Casein kinase II subunit beta >2500.0 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218934 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218934&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 68335528 329994156 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384424 Fc1cc(ccn1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C18H14FN7O2/c19-14-6-9(3-4-20-14)12-7-15(22-11-1-2-11)26-16(23-12)10(8-21-26)5-13-17(27)25-18(28)24-13/h3-8,11,22H,1-2H2,(H2,24,25,27,28)/b13-5- NTLUHAJDTISTSQ-ACAGNQJTSA-N 218935 US9303033, K8, Table 22A, Compound 31::US9303033, P4, Table 13A, Compound 24 Casein kinase II subunit beta 75.4 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218935 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218935&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 69940129 329994157 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 384425 CN(C)c1ccc(cn1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 InChI=1S/C20H20N8O2/c1-27(2)16-6-3-11(9-21-16)14-8-17(23-13-4-5-13)28-18(24-14)12(10-22-28)7-15-19(29)26-20(30)25-15/h3,6-10,13,23H,4-5H2,1-2H3,(H2,25,26,29,30)/b15-7- UDMJTEJFYBAYJS-CHHVJCJISA-N 218936 US9303033, Q4, Table 13A, Compound 25::US9303033, S7, Table 22A, Compound 13 Casein kinase II subunit beta 256.2 7 US Patent 10.7270/Q2CN72RX aid1802518 US9303033 Haddach, M; Tran, JA; Pierre, F; Regan, CF; Raffaele, N; Ravula, S; Ryckman, DM SENHWA BIOSCIENCES, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=218936 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=218936&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 69939749 329994158 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 51303452 OC(=O)c1ccc2c(c1)nc(Nc1cccc(Cl)c1)c1ccncc21 InChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25) MUOKSQABCJCOPU-UHFFFAOYSA-N 50335638 5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-8-carboxylic acid::5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid::CHEMBL1230165::US9062043, Table 13, Compound 17::US9062043, Table 20b, Compound 12 Casein kinase II subunit beta 2000 ChEMBL 10.1021/acs.jmedchem.8b01765 10.7270/Q2SJ1Q27 30689946 Bestgen, B; Kufareva, I; Seetoh, W; Abell, C; Hartmann, RW; Abagyan, R; Le Borgne, M; Filhol, O; Cochet, C; Lomberget, T; Engel, M Universit£ de Lyon http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50335638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50335638&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 3NG 3PE1,6P5S,7Z5N,6ISJ,5O11,6FYP,6FYL,6FYV,6K3L,6KHE,6KHD,6KHF,3NGA,7Z1F,6HMB,7Z1G 24748573 125085740 CHEMBL1230165 ZINC58638454 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 51303453 OC(=O)c1ccc(Nc2nc(cs2)-c2cccc(Br)c2)cc1 InChI=1S/C16H11BrN2O2S/c17-12-3-1-2-11(8-12)14-9-22-16(19-14)18-13-6-4-10(5-7-13)15(20)21/h1-9H,(H,18,19)(H,20,21) BQIQIDNGQSNUJD-UHFFFAOYSA-N 50530325 CHEMBL4458300 Casein kinase II subunit beta 7000 ChEMBL 10.1021/acs.jmedchem.8b01765 10.7270/Q2SJ1Q27 30689946 Bestgen, B; Kufareva, I; Seetoh, W; Abell, C; Hartmann, RW; Abagyan, R; Le Borgne, M; Filhol, O; Cochet, C; Lomberget, T; Engel, M Universit£ de Lyon http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50530325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50530325&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 139593287 440738907 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 51303488 OC(=O)c1ccc(Nc2nc(cs2)-c2ccc3ccccc3c2)cc1O InChI=1S/C20H14N2O3S/c23-18-10-15(7-8-16(18)19(24)25)21-20-22-17(11-26-20)14-6-5-12-3-1-2-4-13(12)9-14/h1-11,23H,(H,21,22)(H,24,25) HUECFCSRZKSRJF-UHFFFAOYSA-N 50530315 CHEMBL4520531 Casein kinase II subunit beta 1000 ChEMBL 10.1021/acs.jmedchem.8b01765 10.7270/Q2SJ1Q27 30689946 Bestgen, B; Kufareva, I; Seetoh, W; Abell, C; Hartmann, RW; Abagyan, R; Le Borgne, M; Filhol, O; Cochet, C; Lomberget, T; Engel, M Universit£ de Lyon http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50530315 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50530315&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search N5Q 6TEW,6YPG,6YPH 7328982 440738897 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 51303498 OC(=O)c1ccc(Nc2nc(cs2)-c2cccc(Br)c2)cc1 InChI=1S/C16H11BrN2O2S/c17-12-3-1-2-11(8-12)14-9-22-16(19-14)18-13-6-4-10(5-7-13)15(20)21/h1-9H,(H,18,19)(H,20,21) BQIQIDNGQSNUJD-UHFFFAOYSA-N 50530325 CHEMBL4458300 Casein kinase II subunit beta 7000 ChEMBL 10.1021/acs.jmedchem.8b01765 10.7270/Q2SJ1Q27 30689946 Bestgen, B; Kufareva, I; Seetoh, W; Abell, C; Hartmann, RW; Abagyan, R; Le Borgne, M; Filhol, O; Cochet, C; Lomberget, T; Engel, M Universit£ de Lyon http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50530325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50530325&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 139593287 440738907 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 51303521 OC(=O)c1ccc(Nc2nc(cs2)-c2ccc3ccccc3c2)cc1O InChI=1S/C20H14N2O3S/c23-18-10-15(7-8-16(18)19(24)25)21-20-22-17(11-26-20)14-6-5-12-3-1-2-4-13(12)9-14/h1-11,23H,(H,21,22)(H,24,25) HUECFCSRZKSRJF-UHFFFAOYSA-N 50530315 CHEMBL4520531 Casein kinase II subunit beta 1000 ChEMBL 10.1021/acs.jmedchem.8b01765 10.7270/Q2SJ1Q27 30689946 Bestgen, B; Kufareva, I; Seetoh, W; Abell, C; Hartmann, RW; Abagyan, R; Le Borgne, M; Filhol, O; Cochet, C; Lomberget, T; Engel, M Universit£ de Lyon http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50530315 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50530315&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search N5Q 6TEW,6YPG,6YPH 7328982 440738897 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 51303530 OC(=O)c1ccc2c(c1)nc(Nc1cccc(Cl)c1)c1ccncc21 InChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25) MUOKSQABCJCOPU-UHFFFAOYSA-N 50335638 5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-8-carboxylic acid::5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid::CHEMBL1230165::US9062043, Table 13, Compound 17::US9062043, Table 20b, Compound 12 Casein kinase II subunit beta 2000 ChEMBL 10.1021/acs.jmedchem.8b01765 10.7270/Q2SJ1Q27 30689946 Bestgen, B; Kufareva, I; Seetoh, W; Abell, C; Hartmann, RW; Abagyan, R; Le Borgne, M; Filhol, O; Cochet, C; Lomberget, T; Engel, M Universit£ de Lyon http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50335638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50335638&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search 3NG 3PE1,6P5S,7Z5N,6ISJ,5O11,6FYP,6FYL,6FYV,6K3L,6KHE,6KHD,6KHF,3NGA,7Z1F,6HMB,7Z1G 24748573 125085740 CHEMBL1230165 ZINC58638454 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 1JWH,1QF8,1RQF,2R6M,3EED,4DGL,4MD7,4MD8,4MD9 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47 51571941 OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2cc(Cl)c(Cl)cc12 InChI=1S/C12H12Cl2N2O4/c13-5-1-7-8(2-6(5)14)16(4-15-7)12-11(19)10(18)9(3-17)20-12/h1-2,4,9-12,17-19H,3H2/t9-,10-,11-,12-/m1/s1 XHSQDZXAVJRBMX-DDHJBXDOSA-N 11324 (2R,3R,4S,5R)-2-(5,6-dichloro-1H-1,3-benzodiazol-1-yl)-5-(hydroxymethyl)oxolane-3,4-diol::5,6-Dichloro-1-.beta.-D-ribofuranosylbenzimidazole::5,6-dichloro-ribofuranosylbenzimidazole::CHEMBL375530::DRB Casein kinase II subunit beta Homo sapiens 23000 ChEMBL 10.1021/acs.jmedchem.2c01523 10.7270/Q22B93GM 36745746 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9122&target=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11324&enzyme=Casein+kinase+II+subunit+beta&column=ki&startPg=0&Increment=50&submit=Search RFZ 3MY1,3MY5,3H30 5894 46511870 CHEMBL375530 DB08473 5178 ZINC03873418 1 MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR 4MD9,4MD8,4MD7,4DGL,2R6M,1JWH,3EED,1QF8,1RQF,1DS5 Casein kinase II subunit beta CSK2B_HUMAN P67870 B0UXA9 P07312 P13862 Q4VX47