BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 377110 CCCCN(CCCC)c1ccc(\C=C(/C#N)C(O)=O)cc1 InChI=1S/C22H33NO/c1-7-23-21(24)16-18(3)11-8-10-17(2)13-14-20-19(4)12-9-15-22(20,5)6/h8,10-11,13-14,16H,7,9,12,15H2,1-6H3,(H,23,24)/b11-8+,14-13+,17-10+,18-16+ WKYDOCGICAMTKE-NBIQJRODSA-N 50092057 CHEMBL3582409::US9296728, 4 Monocarboxylate transporter 1 26 7.43 37.00 C US Patent 10.7270/Q2KH0M5R aid1802446 US9296728 Mereddy, VR; Drewes, LR; Alam, MA; Jonnalagadda, SK; Gurrapu, S Regents of the University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092057 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092057&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 19772866 103990269 CHEMBL3582409 ZINC12504028 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 377111 CCCCCN(CCCCC)c1ccc(\C=C(/C#N)C(O)=O)cc1 InChI=1S/C20H28N2O2/c1-3-5-7-13-22(14-8-6-4-2)19-11-9-17(10-12-19)15-18(16-21)20(23)24/h9-12,15H,3-8,13-14H2,1-2H3,(H,23,24)/b18-15+ WRMVQBCCLSJRCQ-OBGWFSINSA-N 50092017 CHEMBL3582411::US9296728, 5 Monocarboxylate transporter 1 120 7.43 37.00 C US Patent 10.7270/Q2KH0M5R aid1802446 US9296728 Mereddy, VR; Drewes, LR; Alam, MA; Jonnalagadda, SK; Gurrapu, S Regents of the University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092017&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667414 318473159 CHEMBL3582411 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 377112 CCCCCCN(CCCCCC)c1ccc(\C=C(/C#N)C(O)=O)cc1 InChI=1S/C22H32N2O2/c1-3-5-7-9-15-24(16-10-8-6-4-2)21-13-11-19(12-14-21)17-20(18-23)22(25)26/h11-14,17H,3-10,15-16H2,1-2H3,(H,25,26)/b20-17+ NHKITMWAKQWENA-LVZFUZTISA-N 50092016 CHEMBL3582412::US9296728, 6 Monocarboxylate transporter 1 950 7.43 37.00 C US Patent 10.7270/Q2KH0M5R aid1802446 US9296728 Mereddy, VR; Drewes, LR; Alam, MA; Jonnalagadda, SK; Gurrapu, S Regents of the University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092016 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092016&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 19825479 318473158 CHEMBL3582412 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 377113 OC(=O)C(=C\c1ccc(cc1)N(CC=C)CC=C)\C#N InChI=1S/C16H16N2O2/c1-3-9-18(10-4-2)15-7-5-13(6-8-15)11-14(12-17)16(19)20/h3-8,11H,1-2,9-10H2,(H,19,20)/b14-11+ AISGAELWENFDCQ-SDNWHVSQSA-N 50092078 CHEMBL3582413::US9296728, 7 Monocarboxylate transporter 1 88 7.43 37.00 C US Patent 10.7270/Q2KH0M5R aid1802446 US9296728 Mereddy, VR; Drewes, LR; Alam, MA; Jonnalagadda, SK; Gurrapu, S Regents of the University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092078&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667415 103990290 CHEMBL3582413 ZINC36272961 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 377114 OC(=O)C(=C\c1ccc(cc1)N(CC#C)CC#C)\C#N InChI=1S/C16H12N2O2/c1-3-9-18(10-4-2)15-7-5-13(6-8-15)11-14(12-17)16(19)20/h1-2,5-8,11H,9-10H2,(H,19,20)/b14-11+ YOJPLQRGAYWLBC-SDNWHVSQSA-N 50092077 CHEMBL3582414::US9296728, 8 Monocarboxylate transporter 1 340 7.43 37.00 C US Patent 10.7270/Q2KH0M5R aid1802446 US9296728 Mereddy, VR; Drewes, LR; Alam, MA; Jonnalagadda, SK; Gurrapu, S Regents of the University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092077&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667416 103990289 CHEMBL3582414 ZINC34800637 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 377115 CC(C)CN(CC(C)C)c1ccc(\C=C(/C#N)C(O)=O)cc1 InChI=1S/C18H24N2O2/c1-13(2)11-20(12-14(3)4)17-7-5-15(6-8-17)9-16(10-19)18(21)22/h5-9,13-14H,11-12H2,1-4H3,(H,21,22)/b16-9+ OGFXLFTUQIXIEM-CXUHLZMHSA-N 50092018 CHEMBL3582410::US9296728, 9 Monocarboxylate transporter 1 66 7.43 37.00 C US Patent 10.7270/Q2KH0M5R aid1802446 US9296728 Mereddy, VR; Drewes, LR; Alam, MA; Jonnalagadda, SK; Gurrapu, S Regents of the University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092018&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667417 318473160 CHEMBL3582410 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 377116 OC(=O)C(=C\c1ccc(cc1)N(Cc1ccccc1)Cc1ccccc1)\C#N InChI=1S/C24H20N2O2/c25-16-22(24(27)28)15-19-11-13-23(14-12-19)26(17-20-7-3-1-4-8-20)18-21-9-5-2-6-10-21/h1-15H,17-18H2,(H,27,28)/b22-15+ HVZSJLIGRHWSJP-PXLXIMEGSA-N 214695 US9296728, 10 Monocarboxylate transporter 1 43 7.43 37.00 C US Patent 10.7270/Q2KH0M5R aid1802446 US9296728 Mereddy, VR; Drewes, LR; Alam, MA; Jonnalagadda, SK; Gurrapu, S Regents of the University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=214695 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=214695&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667418 329965573 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 377117 OC(=O)C(=C\c1ccc(cc1)N1CCCC1)\C#N InChI=1S/C14H14N2O2/c15-10-12(14(17)18)9-11-3-5-13(6-4-11)16-7-1-2-8-16/h3-6,9H,1-2,7-8H2,(H,17,18)/b12-9+ WSOGLEOJLSVLQF-FMIVXFBMSA-N 50092075 CHEMBL3582416::US9296728, 11 Monocarboxylate transporter 1 64 7.43 37.00 C US Patent 10.7270/Q2KH0M5R aid1802446 US9296728 Mereddy, VR; Drewes, LR; Alam, MA; Jonnalagadda, SK; Gurrapu, S Regents of the University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092075 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092075&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667419 103990287 CHEMBL3582416 ZINC34800641 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 377118 OC(=O)C(=C\c1ccc(cc1)N1CCCCC1)\C#N InChI=1S/C15H16N2O2/c16-11-13(15(18)19)10-12-4-6-14(7-5-12)17-8-2-1-3-9-17/h4-7,10H,1-3,8-9H2,(H,18,19)/b13-10+ JADPBIFXTKFCDU-JLHYYAGUSA-N 50092074 CHEMBL3582417::US9296728, 12 Monocarboxylate transporter 1 110 7.43 37.00 C US Patent 10.7270/Q2KH0M5R aid1802446 US9296728 Mereddy, VR; Drewes, LR; Alam, MA; Jonnalagadda, SK; Gurrapu, S Regents of the University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092074&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 8272191 103990286 CHEMBL3582417 ZINC34800647 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 377119 CCCN(CCC)c1ccc(\C=C(/C#N)C(O)=O)c(OC)c1 InChI=1S/C17H13ClN2O4/c1-9(21)14-8-11-10(5-6-13(23-2)15(11)24-14)17(22)20-12-4-3-7-19-16(12)18/h3-8H,1-2H3,(H,20,22) QHCGTIDBZVWMRI-UHFFFAOYSA-N 50092073 CHEMBL3582418::US9296728, 13 Monocarboxylate transporter 1 9.5 7.43 37.00 C US Patent 10.7270/Q2KH0M5R aid1802446 US9296728 Mereddy, VR; Drewes, LR; Alam, MA; Jonnalagadda, SK; Gurrapu, S Regents of the University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092073&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667547 103990285 CHEMBL3582418 ZINC26267136 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 377120 CCCCN(CCCC)c1ccc(\C=C(/C#N)C(O)=O)c(OC)c1 InChI=1S/C18H16N2O4/c1-10-5-4-8-19-17(10)20-18(22)12-6-7-14(23-3)16-13(12)9-15(24-16)11(2)21/h4-9H,1-3H3,(H,19,20,22) DMEAFSHMAYVGOV-UHFFFAOYSA-N 50092072 CHEMBL3582419::US9296728, 14 Monocarboxylate transporter 1 7.6 7.43 37.00 C US Patent 10.7270/Q2KH0M5R aid1802446 US9296728 Mereddy, VR; Drewes, LR; Alam, MA; Jonnalagadda, SK; Gurrapu, S Regents of the University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092072&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667548 103990284 CHEMBL3582419 ZINC26256005 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 377121 CCCCCN(CCCCC)c1ccc(\C=C(/C#N)C(O)=O)c(OC)c1 InChI=1S/C18H14Cl2N2O4/c1-9(23)15-6-11-10(4-5-14(25-3)17(11)26-15)18(24)22(2)16-12(19)7-21-8-13(16)20/h4-8H,1-3H3 FBVRPENWLNLGLG-UHFFFAOYSA-N 50092070 CHEMBL3582421::US9296728, 15 Monocarboxylate transporter 1 23 7.43 37.00 C US Patent 10.7270/Q2KH0M5R aid1802446 US9296728 Mereddy, VR; Drewes, LR; Alam, MA; Jonnalagadda, SK; Gurrapu, S Regents of the University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092070 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092070&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667549 103990282 CHEMBL3582421 ZINC26276047 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 377122 COc1cc(ccc1\C=C(/C#N)C(O)=O)N(CC=C)CC=C InChI=1S/C17H14Cl2N2O3/c1-3-9-6-11-10(4-5-14(23-2)16(11)24-9)17(22)21-15-12(18)7-20-8-13(15)19/h4-8H,3H2,1-2H3,(H,20,21,22) VQTBBBGKBIKAAN-UHFFFAOYSA-N 50092067 CHEMBL3582424::US9296728, 16 Monocarboxylate transporter 1 25 7.43 37.00 C US Patent 10.7270/Q2KH0M5R aid1802446 US9296728 Mereddy, VR; Drewes, LR; Alam, MA; Jonnalagadda, SK; Gurrapu, S Regents of the University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092067&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667550 103990279 CHEMBL3582424 ZINC26253942 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 377123 COc1cc(ccc1\C=C(/C#N)C(O)=O)N(CC#C)CC#C InChI=1S/C17H14N2O3/c1-4-8-19(9-5-2)15-7-6-13(16(11-15)22-3)10-14(12-18)17(20)21/h1-2,6-7,10-11H,8-9H2,3H3,(H,20,21)/b14-10+ AUELJRMSNKLDTD-GXDHUFHOSA-N 214696 US9296728, 17 Monocarboxylate transporter 1 91 7.43 37.00 C US Patent 10.7270/Q2KH0M5R aid1802446 US9296728 Mereddy, VR; Drewes, LR; Alam, MA; Jonnalagadda, SK; Gurrapu, S Regents of the University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=214696 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=214696&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667551 329965574 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 377124 COc1cc(ccc1\C=C(/C#N)C(O)=O)N(CC(C)C)CC(C)C InChI=1S/C16H10Cl2N2O5/c1-24-11-3-2-7(8-4-12(16(22)23)25-14(8)11)15(21)20-13-9(17)5-19-6-10(13)18/h2-6H,1H3,(H,22,23)(H,19,20,21) JJFBEGVKIVBBHB-UHFFFAOYSA-N 50092071 CHEMBL3582420::US9296728, 18 Monocarboxylate transporter 1 15 7.43 37.00 C US Patent 10.7270/Q2KH0M5R aid1802446 US9296728 Mereddy, VR; Drewes, LR; Alam, MA; Jonnalagadda, SK; Gurrapu, S Regents of the University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092071&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667552 103990283 CHEMBL3582420 ZINC26251681 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 377125 COc1cc(ccc1\C=C(/C#N)C(O)=O)N(Cc1ccccc1)Cc1ccccc1 InChI=1S/C25H22N2O3/c1-30-24-15-23(13-12-21(24)14-22(16-26)25(28)29)27(17-19-8-4-2-5-9-19)18-20-10-6-3-7-11-20/h2-15H,17-18H2,1H3,(H,28,29)/b22-14+ VOPFDHPGYLVCCO-HYARGMPZSA-N 214697 US9296728, 19 Monocarboxylate transporter 1 19 7.43 37.00 C US Patent 10.7270/Q2KH0M5R aid1802446 US9296728 Mereddy, VR; Drewes, LR; Alam, MA; Jonnalagadda, SK; Gurrapu, S Regents of the University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=214697 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=214697&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667553 329965575 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 377126 COc1cc(ccc1\C=C(/C#N)C(O)=O)N(c1ccccc1)c1ccccc1 InChI=1S/C17H13ClN2O4/c1-9(21)15-7-11-10(3-4-14(23-2)16(11)24-15)17(22)20-13-5-6-19-8-12(13)18/h3-8H,1-2H3,(H,19,20,22) SHWIKYNKCMPTHS-UHFFFAOYSA-N 50092069 CHEMBL3582422::US9296728, 20 Monocarboxylate transporter 1 8 7.43 37.00 C US Patent 10.7270/Q2KH0M5R aid1802446 US9296728 Mereddy, VR; Drewes, LR; Alam, MA; Jonnalagadda, SK; Gurrapu, S Regents of the University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092069 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092069&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71623055 103990281 CHEMBL3582422 ZINC26267142 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 377127 COc1cc(ccc1\C=C(/C#N)C(O)=O)N1CCCC1 InChI=1S/C15H16N2O3/c1-20-14-9-13(17-6-2-3-7-17)5-4-11(14)8-12(10-16)15(18)19/h4-5,8-9H,2-3,6-7H2,1H3,(H,18,19)/b12-8+ JIYZMSFJSKOOBF-XYOKQWHBSA-N 214698 US9296728, 21 Monocarboxylate transporter 1 59 7.43 37.00 C US Patent 10.7270/Q2KH0M5R aid1802446 US9296728 Mereddy, VR; Drewes, LR; Alam, MA; Jonnalagadda, SK; Gurrapu, S Regents of the University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=214698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=214698&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667684 329965576 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 377128 CCCN(CCC)c1ccc2cc(C(O)=O)c(=O)oc2c1 InChI=1S/C16H19NO4/c1-3-7-17(8-4-2)12-6-5-11-9-13(15(18)19)16(20)21-14(11)10-12/h5-6,9-10H,3-4,7-8H2,1-2H3,(H,18,19) HUMXOCRYJWDWNY-UHFFFAOYSA-N 214699 US9296728, 22 Monocarboxylate transporter 1 299 7.43 37.00 C US Patent 10.7270/Q2KH0M5R aid1802446 US9296728 Mereddy, VR; Drewes, LR; Alam, MA; Jonnalagadda, SK; Gurrapu, S Regents of the University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=214699 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=214699&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667685 329965577 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 377129 OC(=O)c1cc2ccc(cc2oc1=O)N(CC=C)CC=C InChI=1S/C16H15NO4/c1-3-7-17(8-4-2)12-6-5-11-9-13(15(18)19)16(20)21-14(11)10-12/h3-6,9-10H,1-2,7-8H2,(H,18,19) CNKJPGDJYDBWCI-UHFFFAOYSA-N 214700 US9296728, 23 Monocarboxylate transporter 1 250 7.43 37.00 C US Patent 10.7270/Q2KH0M5R aid1802446 US9296728 Mereddy, VR; Drewes, LR; Alam, MA; Jonnalagadda, SK; Gurrapu, S Regents of the University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=214700 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=214700&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667686 329965578 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 377130 OC(=O)c1cc2ccc(cc2oc1=O)N(CC#C)CC#C InChI=1S/C16H11NO4/c1-3-7-17(8-4-2)12-6-5-11-9-13(15(18)19)16(20)21-14(11)10-12/h1-2,5-6,9-10H,7-8H2,(H,18,19) UDBJVBGONKDLFY-UHFFFAOYSA-N 214701 US9296728, 24 Monocarboxylate transporter 1 150 7.43 37.00 C US Patent 10.7270/Q2KH0M5R aid1802446 US9296728 Mereddy, VR; Drewes, LR; Alam, MA; Jonnalagadda, SK; Gurrapu, S Regents of the University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=214701 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=214701&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667687 329965579 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 377131 OC(=O)c1cc2ccc(cc2oc1=O)N(Cc1ccccc1)Cc1ccccc1 InChI=1S/C24H19NO4/c26-23(27)21-13-19-11-12-20(14-22(19)29-24(21)28)25(15-17-7-3-1-4-8-17)16-18-9-5-2-6-10-18/h1-14H,15-16H2,(H,26,27) JRHSORWQTHPWJB-UHFFFAOYSA-N 214702 US9296728, 25 Monocarboxylate transporter 1 48 7.43 37.00 C US Patent 10.7270/Q2KH0M5R aid1802446 US9296728 Mereddy, VR; Drewes, LR; Alam, MA; Jonnalagadda, SK; Gurrapu, S Regents of the University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=214702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=214702&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667688 329965580 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 377132 OC(=O)c1cc2ccc(cc2oc1=O)N1CCCC1 InChI=1S/C14H13NO4/c16-13(17)11-7-9-3-4-10(15-5-1-2-6-15)8-12(9)19-14(11)18/h3-4,7-8H,1-2,5-6H2,(H,16,17) AZGXIHFVKOMJRL-UHFFFAOYSA-N 50442702 CHEMBL2442511::US9296728, 26 Monocarboxylate transporter 1 220 7.43 37.00 C US Patent 10.7270/Q2KH0M5R aid1802446 US9296728 Mereddy, VR; Drewes, LR; Alam, MA; Jonnalagadda, SK; Gurrapu, S Regents of the University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50442702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50442702&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667689 175455019 CHEMBL2442511 ZINC96286380 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 377133 OC(=O)c1cc2ccc(cc2oc1=O)N(Cc1ccc(F)cc1)Cc1ccc(F)cc1 InChI=1S/C24H17F2NO4/c25-18-6-1-15(2-7-18)13-27(14-16-3-8-19(26)9-4-16)20-10-5-17-11-21(23(28)29)24(30)31-22(17)12-20/h1-12H,13-14H2,(H,28,29) QIMUJZXUWHPQCH-UHFFFAOYSA-N 214703 US9296728, 27 Monocarboxylate transporter 1 200 7.43 37.00 C US Patent 10.7270/Q2KH0M5R aid1802446 US9296728 Mereddy, VR; Drewes, LR; Alam, MA; Jonnalagadda, SK; Gurrapu, S Regents of the University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=214703 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=214703&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667690 329965581 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 377134 OC(=O)c1cc2ccc(cc2oc1=O)N(Cc1ccc(Cl)cc1)Cc1ccc(Cl)cc1 InChI=1S/C24H17Cl2NO4/c25-18-6-1-15(2-7-18)13-27(14-16-3-8-19(26)9-4-16)20-10-5-17-11-21(23(28)29)24(30)31-22(17)12-20/h1-12H,13-14H2,(H,28,29) DBYIZUGYTCROSW-UHFFFAOYSA-N 214704 US9296728, 28 Monocarboxylate transporter 1 920 7.43 37.00 C US Patent 10.7270/Q2KH0M5R aid1802446 US9296728 Mereddy, VR; Drewes, LR; Alam, MA; Jonnalagadda, SK; Gurrapu, S Regents of the University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=214704 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=214704&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667835 329965582 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 377135 OC(=O)c1cc2ccc(cc2oc1=O)N(Cc1ccc2OCOc2c1)Cc1ccc2OCOc2c1 InChI=1S/C26H19NO8/c28-25(29)19-9-17-3-4-18(10-22(17)35-26(19)30)27(11-15-1-5-20-23(7-15)33-13-31-20)12-16-2-6-21-24(8-16)34-14-32-21/h1-10H,11-14H2,(H,28,29) JDYUAPKUEHRILP-UHFFFAOYSA-N 214705 US9296728, 29 Monocarboxylate transporter 1 110 7.43 37.00 C US Patent 10.7270/Q2KH0M5R aid1802446 US9296728 Mereddy, VR; Drewes, LR; Alam, MA; Jonnalagadda, SK; Gurrapu, S Regents of the University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=214705 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=214705&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667836 329965583 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50348677 CCCCCCN(CCCCCC)c1ccc(\C=C(/C#N)C(O)=O)cc1 InChI=1S/C22H32N2O2/c1-3-5-7-9-15-24(16-10-8-6-4-2)21-13-11-19(12-14-21)17-20(18-23)22(25)26/h11-14,17H,3-10,15-16H2,1-2H3,(H,25,26)/b20-17+ NHKITMWAKQWENA-LVZFUZTISA-N 50092016 CHEMBL3582412::US9296728, 6 Monocarboxylate transporter 1 880 ChEMBL 10.1021/acsmedchemlett.5b00049 10.7270/Q2ZC84MV 26005533 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Nelson, GL; Sneve, MG; Drewes, LR; Mereddy, VR Medical School Duluth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092016 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092016&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 19825479 318473158 CHEMBL3582412 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50348678 CCCCCN(CCCCC)c1ccc(\C=C(/C#N)C(O)=O)cc1 InChI=1S/C20H28N2O2/c1-3-5-7-13-22(14-8-6-4-2)19-11-9-17(10-12-19)15-18(16-21)20(23)24/h9-12,15H,3-8,13-14H2,1-2H3,(H,23,24)/b18-15+ WRMVQBCCLSJRCQ-OBGWFSINSA-N 50092017 CHEMBL3582411::US9296728, 5 Monocarboxylate transporter 1 140 ChEMBL 10.1021/acsmedchemlett.5b00049 10.7270/Q2ZC84MV 26005533 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Nelson, GL; Sneve, MG; Drewes, LR; Mereddy, VR Medical School Duluth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092017&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667414 318473159 CHEMBL3582411 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50348679 CC(C)CN(CC(C)C)c1ccc(\C=C(/C#N)C(O)=O)cc1 InChI=1S/C18H24N2O2/c1-13(2)11-20(12-14(3)4)17-7-5-15(6-8-17)9-16(10-19)18(21)22/h5-9,13-14H,11-12H2,1-4H3,(H,21,22)/b16-9+ OGFXLFTUQIXIEM-CXUHLZMHSA-N 50092018 CHEMBL3582410::US9296728, 9 Monocarboxylate transporter 1 100 ChEMBL 10.1021/acsmedchemlett.5b00049 10.7270/Q2ZC84MV 26005533 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Nelson, GL; Sneve, MG; Drewes, LR; Mereddy, VR Medical School Duluth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092018&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667417 318473160 CHEMBL3582410 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50348680 CCCCN(CCCC)c1ccc(\C=C(/C#N)C(O)=O)cc1 InChI=1S/C22H33NO/c1-7-23-21(24)16-18(3)11-8-10-17(2)13-14-20-19(4)12-9-15-22(20,5)6/h8,10-11,13-14,16H,7,9,12,15H2,1-6H3,(H,23,24)/b11-8+,14-13+,17-10+,18-16+ WKYDOCGICAMTKE-NBIQJRODSA-N 50092057 CHEMBL3582409::US9296728, 4 Monocarboxylate transporter 1 30 ChEMBL 10.1021/acsmedchemlett.5b00049 10.7270/Q2ZC84MV 26005533 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Nelson, GL; Sneve, MG; Drewes, LR; Mereddy, VR Medical School Duluth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092057 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092057&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 19772866 103990269 CHEMBL3582409 ZINC12504028 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50348681 CCCN(CCC)c1ccc(\C=C(/C#N)C(O)=O)cc1 InChI=1S/C17H12Cl2N2O4/c1-8(22)14-5-10-9(3-4-13(24-2)16(10)25-14)17(23)21-15-11(18)6-20-7-12(15)19/h3-7H,1-2H3,(H,20,21,23) IURSWTQMXOIIAU-UHFFFAOYSA-N 50092058 CHEMBL3582408 Monocarboxylate transporter 1 10.0 ChEMBL 10.1021/acsmedchemlett.5b00049 10.7270/Q2ZC84MV 26005533 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Nelson, GL; Sneve, MG; Drewes, LR; Mereddy, VR Medical School Duluth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092058 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092058&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 8272111 103990270 CHEMBL3582408 ZINC00602183 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50348682 CCN(CC)c1ccc(\C=C(/C#N)C(O)=O)cc1 InChI=1S/C16H12ClN3O4/c1-8(21)13-5-10-9(3-4-12(23-2)14(10)24-13)16(22)20-15-11(17)6-18-7-19-15/h3-7H,1-2H3,(H,18,19,20,22) RAFCFNZBQHYJSO-UHFFFAOYSA-N 50092059 CHEMBL3582407 Monocarboxylate transporter 1 70 ChEMBL 10.1021/acsmedchemlett.5b00049 10.7270/Q2ZC84MV 26005533 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Nelson, GL; Sneve, MG; Drewes, LR; Mereddy, VR Medical School Duluth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092059 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092059&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 5376626 103990271 CHEMBL3582407 ZINC26255998 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50348683 CN(C)c1ccc(\C=C(/C#N)C(O)=O)cc1 InChI=1S/C12H12N2O2/c1-14(2)11-5-3-9(4-6-11)7-10(8-13)12(15)16/h3-7H,1-2H3,(H,15,16)/b10-7+ CXZXLLVNQYUMAW-JXMROGBWSA-N 4345 (2E)-2-cyano-3-[4-(dimethylamino)phenyl]prop-2-enoic acid::benzylidenemalononitrile (BMN) deriv. 29 Monocarboxylate transporter 1 140 ChEMBL 10.1021/acsmedchemlett.5b00049 10.7270/Q2ZC84MV 26005533 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Nelson, GL; Sneve, MG; Drewes, LR; Mereddy, VR Medical School Duluth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4345 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4345&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 1550166 8034022 ZINC00130232 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50348685 OC(=O)C(=C\c1ccc2OCOc2c1)\C#N InChI=1S/C18H14Cl2N2O4/c1-8-14-10(18(24)22-15-11(19)6-21-7-12(15)20)4-5-13(25-3)17(14)26-16(8)9(2)23/h4-7H,1-3H3,(H,21,22,24) WHVLKHKNUNQGLI-UHFFFAOYSA-N 50092060 CHEMBL3582406 Monocarboxylate transporter 1 500 ChEMBL 10.1021/acsmedchemlett.5b00049 10.7270/Q2ZC84MV 26005533 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Nelson, GL; Sneve, MG; Drewes, LR; Mereddy, VR Medical School Duluth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092060 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092060&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 5715288 103990272 CHEMBL3582406 ZINC26259888 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50348686 COc1ccc(\C=C(/C#N)C(O)=O)cc1 InChI=1S/C11H9NO3/c1-15-10-4-2-8(3-5-10)6-9(7-12)11(13)14/h2-6H,1H3,(H,13,14)/b9-6+ KMHNRJDDHTZZDZ-RMKNXTFCSA-N 4343 (2E)-2-cyano-3-(4-methoxyphenyl)prop-2-enoic acid::benzylidenemalononitrile (BMN) deriv. 27 Monocarboxylate transporter 1 500 ChEMBL 10.1021/acsmedchemlett.5b00049 10.7270/Q2ZC84MV 26005533 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Nelson, GL; Sneve, MG; Drewes, LR; Mereddy, VR Medical School Duluth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4343 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4343&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 736236 8034020 ZINC00156538 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50348687 OC(=O)C(=C\c1ccc(cc1)[N+]([O-])=O)\C#N InChI=1S/C10H6N2O4/c11-6-8(10(13)14)5-7-1-3-9(4-2-7)12(15)16/h1-5H,(H,13,14)/b8-5+ WVRIVHWJJWXSTM-VMPITWQZSA-N 4347 (2E)-2-cyano-3-(4-nitrophenyl)prop-2-enoic acid::benzylidenemalononitrile (BMN) deriv. 31::p-Nitro-a-cyanocinnamic Acid Monocarboxylate transporter 1 500 ChEMBL 10.1021/acsmedchemlett.5b00049 10.7270/Q2ZC84MV 26005533 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Nelson, GL; Sneve, MG; Drewes, LR; Mereddy, VR Medical School Duluth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4347&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 5328789 8034024 ZINC14944539 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50348688 OC(=O)C(=C\c1ccc(cc1)C#N)\C#N InChI=1S/C21H13Cl2N3O4/c1-29-16-3-2-12(21(28)26-18-14(22)9-25-10-15(18)23)13-8-17(30-20(13)16)19(27)11-4-6-24-7-5-11/h2-10H,1H3,(H,25,26,28) UHJAPZBOKPPKGD-UHFFFAOYSA-N 50092061 CHEMBL3582405 Monocarboxylate transporter 1 500 ChEMBL 10.1021/acsmedchemlett.5b00049 10.7270/Q2ZC84MV 26005533 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Nelson, GL; Sneve, MG; Drewes, LR; Mereddy, VR Medical School Duluth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092061 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092061&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 5388688 103990273 CHEMBL3582405 ZINC26272955 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50348689 OC(=O)C(=C\c1ccc(Br)cc1)\C#N InChI=1S/C16H9Cl2N3O3/c1-23-13-3-2-9(10-4-8(5-19)24-15(10)13)16(22)21-14-11(17)6-20-7-12(14)18/h2-4,6-7H,1H3,(H,20,21,22) ATETVUDHVLJVIY-UHFFFAOYSA-N 50092062 CHEMBL3582404 Monocarboxylate transporter 1 500 ChEMBL 10.1021/acsmedchemlett.5b00049 10.7270/Q2ZC84MV 26005533 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Nelson, GL; Sneve, MG; Drewes, LR; Mereddy, VR Medical School Duluth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092062 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092062&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 15556465 103990274 CHEMBL3582404 ZINC26257573 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50348690 OC(=O)C(=C\c1ccc(Cl)cc1)\C#N InChI=1S/C10H6ClNO2/c11-9-3-1-7(2-4-9)5-8(6-12)10(13)14/h1-5H,(H,13,14)/b8-5+ MXCRRKYUQNHWLJ-VMPITWQZSA-N 50092063 CHEMBL3582403 Monocarboxylate transporter 1 500 ChEMBL 10.1021/acsmedchemlett.5b00049 10.7270/Q2ZC84MV 26005533 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Nelson, GL; Sneve, MG; Drewes, LR; Mereddy, VR Medical School Duluth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092063 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092063&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 2363776 103990275 CHEMBL3582403 ZINC26275455 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50348692 OC(=O)C(=C\c1ccc(F)cc1)\C#N InChI=1S/C10H6FNO2/c11-9-3-1-7(2-4-9)5-8(6-12)10(13)14/h1-5H,(H,13,14)/b8-5+ OBZAFMILNGLRAL-VMPITWQZSA-N 4344 (2E)-2-cyano-3-(4-fluorophenyl)prop-2-enoic acid::benzylidenemalononitrile (BMN) deriv. 28 Monocarboxylate transporter 1 500 ChEMBL 10.1021/acsmedchemlett.5b00049 10.7270/Q2ZC84MV 26005533 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Nelson, GL; Sneve, MG; Drewes, LR; Mereddy, VR Medical School Duluth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4344&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 1550170 8034021 ZINC01625445 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50348693 CCc1ccc(\C=C(/C#N)C(O)=O)cc1 InChI=1S/C19H12Cl2N2O4/c1-9(24)16-7-12-11(3-4-15(26-2)18(12)27-16)19(25)23-17-13(20)5-10(8-22)6-14(17)21/h3-7H,1-2H3,(H,23,25) IPVSYDHNAKLEPK-UHFFFAOYSA-N 50092064 CHEMBL3582402 Monocarboxylate transporter 1 500 ChEMBL 10.1021/acsmedchemlett.5b00049 10.7270/Q2ZC84MV 26005533 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Nelson, GL; Sneve, MG; Drewes, LR; Mereddy, VR Medical School Duluth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092064&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 8271996 103990276 CHEMBL3582402 ZINC26254074 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50348695 Cc1ccc(\C=C(/C#N)C(O)=O)cc1 InChI=1S/C11H9NO2/c1-8-2-4-9(5-3-8)6-10(7-12)11(13)14/h2-6H,1H3,(H,13,14)/b10-6+ VSMAAVBAABUVMQ-UXBLZVDNSA-N 4346 (2E)-2-cyano-3-(4-methylphenyl)prop-2-enoic acid::benzylidenemalononitrile (BMN) deriv. 30 Monocarboxylate transporter 1 500 ChEMBL 10.1021/acsmedchemlett.5b00049 10.7270/Q2ZC84MV 26005533 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Nelson, GL; Sneve, MG; Drewes, LR; Mereddy, VR Medical School Duluth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4346&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 1558661 8034023 ZINC00163685 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50348696 [Na+].COc1cc(ccc1\C=C(/C#N)C([O-])=O)N1CCCCC1 InChI=1S/C20H20Cl2N2O3/c1-20(2,3)8-11-7-13-12(5-6-16(26-4)18(13)27-11)19(25)24-17-14(21)9-23-10-15(17)22/h5-7,9-10H,8H2,1-4H3,(H,23,24,25) OCELOSKSDRCMQK-UHFFFAOYSA-N 50092065 CHEMBL3582426 Monocarboxylate transporter 1 25 ChEMBL 10.1021/acsmedchemlett.5b00049 10.7270/Q2ZC84MV 26005533 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Nelson, GL; Sneve, MG; Drewes, LR; Mereddy, VR Medical School Duluth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092065&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 122179538 103990277 CHEMBL3582426 ZINC26270573 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50348697 [Na+].COc1cc(ccc1\C=C(/C#N)C([O-])=O)N1CCCC1 InChI=1S/C18H14ClNO4/c1-10(21)16-9-12-11(7-8-15(23-2)17(12)24-16)18(22)20-14-6-4-3-5-13(14)19/h3-9H,1-2H3,(H,20,22) MPXKKKYXZROOTK-UHFFFAOYSA-N 50092066 CHEMBL3582425 Monocarboxylate transporter 1 48 ChEMBL 10.1021/acsmedchemlett.5b00049 10.7270/Q2ZC84MV 26005533 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Nelson, GL; Sneve, MG; Drewes, LR; Mereddy, VR Medical School Duluth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092066&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 122179537 103990278 CHEMBL3582425 ZINC26267647 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50348698 COc1cc(ccc1\C=C(/C#N)C(O)=O)N(CC=C)CC=C InChI=1S/C17H14Cl2N2O3/c1-3-9-6-11-10(4-5-14(23-2)16(11)24-9)17(22)21-15-12(18)7-20-8-13(15)19/h4-8H,3H2,1-2H3,(H,20,21,22) VQTBBBGKBIKAAN-UHFFFAOYSA-N 50092067 CHEMBL3582424::US9296728, 16 Monocarboxylate transporter 1 29 ChEMBL 10.1021/acsmedchemlett.5b00049 10.7270/Q2ZC84MV 26005533 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Nelson, GL; Sneve, MG; Drewes, LR; Mereddy, VR Medical School Duluth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092067&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667550 103990279 CHEMBL3582424 ZINC26253942 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50348699 [Na+].COc1cc(ccc1\C=C(/C#N)C([O-])=O)N(c1ccccc1)c1ccccc1 InChI=1S/C17H14N2O4/c1-10(20)15-9-13-12(3-4-14(22-2)16(13)23-15)17(21)19-11-5-7-18-8-6-11/h3-9H,1-2H3,(H,18,19,21) PVLQCKVDYPCWRJ-UHFFFAOYSA-N 50092068 CHEMBL3582423 Monocarboxylate transporter 1 11 ChEMBL 10.1021/acsmedchemlett.5b00049 10.7270/Q2ZC84MV 26005533 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Nelson, GL; Sneve, MG; Drewes, LR; Mereddy, VR Medical School Duluth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092068 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092068&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 122179536 103990280 CHEMBL3582423 ZINC00022327 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50348700 COc1cc(ccc1\C=C(/C#N)C(O)=O)N(c1ccccc1)c1ccccc1 InChI=1S/C17H13ClN2O4/c1-9(21)15-7-11-10(3-4-14(23-2)16(11)24-15)17(22)20-13-5-6-19-8-12(13)18/h3-8H,1-2H3,(H,19,20,22) SHWIKYNKCMPTHS-UHFFFAOYSA-N 50092069 CHEMBL3582422::US9296728, 20 Monocarboxylate transporter 1 8.0 ChEMBL 10.1021/acsmedchemlett.5b00049 10.7270/Q2ZC84MV 26005533 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Nelson, GL; Sneve, MG; Drewes, LR; Mereddy, VR Medical School Duluth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092069 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092069&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71623055 103990281 CHEMBL3582422 ZINC26267142 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50348701 CCCCCN(CCCCC)c1ccc(\C=C(/C#N)C(O)=O)c(OC)c1 InChI=1S/C18H14Cl2N2O4/c1-9(23)15-6-11-10(4-5-14(25-3)17(11)26-15)18(24)22(2)16-12(19)7-21-8-13(16)20/h4-8H,1-3H3 FBVRPENWLNLGLG-UHFFFAOYSA-N 50092070 CHEMBL3582421::US9296728, 15 Monocarboxylate transporter 1 34 ChEMBL 10.1021/acsmedchemlett.5b00049 10.7270/Q2ZC84MV 26005533 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Nelson, GL; Sneve, MG; Drewes, LR; Mereddy, VR Medical School Duluth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092070 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092070&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667549 103990282 CHEMBL3582421 ZINC26276047 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50348702 COc1cc(ccc1\C=C(/C#N)C(O)=O)N(CC(C)C)CC(C)C InChI=1S/C16H10Cl2N2O5/c1-24-11-3-2-7(8-4-12(16(22)23)25-14(8)11)15(21)20-13-9(17)5-19-6-10(13)18/h2-6H,1H3,(H,22,23)(H,19,20,21) JJFBEGVKIVBBHB-UHFFFAOYSA-N 50092071 CHEMBL3582420::US9296728, 18 Monocarboxylate transporter 1 11 ChEMBL 10.1021/acsmedchemlett.5b00049 10.7270/Q2ZC84MV 26005533 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Nelson, GL; Sneve, MG; Drewes, LR; Mereddy, VR Medical School Duluth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092071&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667552 103990283 CHEMBL3582420 ZINC26251681 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50348704 CCCCN(CCCC)c1ccc(\C=C(/C#N)C(O)=O)c(OC)c1 InChI=1S/C18H16N2O4/c1-10-5-4-8-19-17(10)20-18(22)12-6-7-14(23-3)16-13(12)9-15(24-16)11(2)21/h4-9H,1-3H3,(H,19,20,22) DMEAFSHMAYVGOV-UHFFFAOYSA-N 50092072 CHEMBL3582419::US9296728, 14 Monocarboxylate transporter 1 9.0 ChEMBL 10.1021/acsmedchemlett.5b00049 10.7270/Q2ZC84MV 26005533 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Nelson, GL; Sneve, MG; Drewes, LR; Mereddy, VR Medical School Duluth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092072&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667548 103990284 CHEMBL3582419 ZINC26256005 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50348705 CCCN(CCC)c1ccc(\C=C(/C#N)C(O)=O)c(OC)c1 InChI=1S/C17H13ClN2O4/c1-9(21)14-8-11-10(5-6-13(23-2)15(11)24-14)17(22)20-12-4-3-7-19-16(12)18/h3-8H,1-2H3,(H,20,22) QHCGTIDBZVWMRI-UHFFFAOYSA-N 50092073 CHEMBL3582418::US9296728, 13 Monocarboxylate transporter 1 12 ChEMBL 10.1021/acsmedchemlett.5b00049 10.7270/Q2ZC84MV 26005533 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Nelson, GL; Sneve, MG; Drewes, LR; Mereddy, VR Medical School Duluth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092073&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667547 103990285 CHEMBL3582418 ZINC26267136 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50348708 OC(=O)C(=C\c1ccc(cc1)N1CCCCC1)\C#N InChI=1S/C15H16N2O2/c16-11-13(15(18)19)10-12-4-6-14(7-5-12)17-8-2-1-3-9-17/h4-7,10H,1-3,8-9H2,(H,18,19)/b13-10+ JADPBIFXTKFCDU-JLHYYAGUSA-N 50092074 CHEMBL3582417::US9296728, 12 Monocarboxylate transporter 1 140 ChEMBL 10.1021/acsmedchemlett.5b00049 10.7270/Q2ZC84MV 26005533 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Nelson, GL; Sneve, MG; Drewes, LR; Mereddy, VR Medical School Duluth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092074&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 8272191 103990286 CHEMBL3582417 ZINC34800647 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50348712 OC(=O)C(=C\c1ccc(cc1)N1CCCC1)\C#N InChI=1S/C14H14N2O2/c15-10-12(14(17)18)9-11-3-5-13(6-4-11)16-7-1-2-8-16/h3-6,9H,1-2,7-8H2,(H,17,18)/b12-9+ WSOGLEOJLSVLQF-FMIVXFBMSA-N 50092075 CHEMBL3582416::US9296728, 11 Monocarboxylate transporter 1 70 ChEMBL 10.1021/acsmedchemlett.5b00049 10.7270/Q2ZC84MV 26005533 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Nelson, GL; Sneve, MG; Drewes, LR; Mereddy, VR Medical School Duluth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092075 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092075&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667419 103990287 CHEMBL3582416 ZINC34800641 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50348715 OC(=O)C(=C\c1ccc(cc1)N(c1ccccc1)c1ccccc1)\C#N InChI=1S/C22H16N2O2/c23-16-18(22(25)26)15-17-11-13-21(14-12-17)24(19-7-3-1-4-8-19)20-9-5-2-6-10-20/h1-15H,(H,25,26)/b18-15+ DTGGJUIFYJXAJI-OBGWFSINSA-N 50092076 CHEMBL3582415 Monocarboxylate transporter 1 30 ChEMBL 10.1021/acsmedchemlett.5b00049 10.7270/Q2ZC84MV 26005533 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Nelson, GL; Sneve, MG; Drewes, LR; Mereddy, VR Medical School Duluth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092076&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 27160378 103990288 CHEMBL3582415 ZINC34800645 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50348720 OC(=O)C(=C\c1ccc(cc1)N(CC#C)CC#C)\C#N InChI=1S/C16H12N2O2/c1-3-9-18(10-4-2)15-7-5-13(6-8-15)11-14(12-17)16(19)20/h1-2,5-8,11H,9-10H2,(H,19,20)/b14-11+ YOJPLQRGAYWLBC-SDNWHVSQSA-N 50092077 CHEMBL3582414::US9296728, 8 Monocarboxylate transporter 1 400 ChEMBL 10.1021/acsmedchemlett.5b00049 10.7270/Q2ZC84MV 26005533 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Nelson, GL; Sneve, MG; Drewes, LR; Mereddy, VR Medical School Duluth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092077&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667416 103990289 CHEMBL3582414 ZINC34800637 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50348721 OC(=O)C(=C\c1ccc(cc1)N(CC=C)CC=C)\C#N InChI=1S/C16H16N2O2/c1-3-9-18(10-4-2)15-7-5-13(6-8-15)11-14(12-17)16(19)20/h3-8,11H,1-2,9-10H2,(H,19,20)/b14-11+ AISGAELWENFDCQ-SDNWHVSQSA-N 50092078 CHEMBL3582413::US9296728, 7 Monocarboxylate transporter 1 110 ChEMBL 10.1021/acsmedchemlett.5b00049 10.7270/Q2ZC84MV 26005533 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Nelson, GL; Sneve, MG; Drewes, LR; Mereddy, VR Medical School Duluth http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092078&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667415 103990290 CHEMBL3582413 ZINC36272961 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50500621 OC(=O)c1cc2ccc(cc2oc1=O)N(CC#C)CC#C InChI=1S/C16H11NO4/c1-3-7-17(8-4-2)12-6-5-11-9-13(15(18)19)16(20)21-14(11)10-12/h1-2,5-6,9-10H,7-8H2,(H,18,19) UDBJVBGONKDLFY-UHFFFAOYSA-N 214701 US9296728, 24 Monocarboxylate transporter 1 210 ChEMBL 10.1016/j.bmcl.2016.05.054 10.7270/Q2BP04QP 27241692 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Ronayne, CT; Nelson, GL; Solano, LN; Lueth, EA; Drewes, LR; Mereddy, VR University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=214701 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=214701&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667687 329965579 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50500622 OC(=O)c1cc2ccc(cc2oc1=O)N(CC=C)CC=C InChI=1S/C16H15NO4/c1-3-7-17(8-4-2)12-6-5-11-9-13(15(18)19)16(20)21-14(11)10-12/h3-6,9-10H,1-2,7-8H2,(H,18,19) CNKJPGDJYDBWCI-UHFFFAOYSA-N 214700 US9296728, 23 Monocarboxylate transporter 1 170 ChEMBL 10.1016/j.bmcl.2016.05.054 10.7270/Q2BP04QP 27241692 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Ronayne, CT; Nelson, GL; Solano, LN; Lueth, EA; Drewes, LR; Mereddy, VR University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=214700 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=214700&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667686 329965578 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50500623 CCCN(CCC)c1ccc2cc(C(O)=O)c(=O)oc2c1 InChI=1S/C16H19NO4/c1-3-7-17(8-4-2)12-6-5-11-9-13(15(18)19)16(20)21-14(11)10-12/h5-6,9-10H,3-4,7-8H2,1-2H3,(H,18,19) HUMXOCRYJWDWNY-UHFFFAOYSA-N 214699 US9296728, 22 Monocarboxylate transporter 1 450 ChEMBL 10.1016/j.bmcl.2016.05.054 10.7270/Q2BP04QP 27241692 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Ronayne, CT; Nelson, GL; Solano, LN; Lueth, EA; Drewes, LR; Mereddy, VR University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=214699 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=214699&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667685 329965577 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50500624 OC(=O)c1cc2ccc(cc2oc1=O)N1CCCC1 InChI=1S/C14H13NO4/c16-13(17)11-7-9-3-4-10(15-5-1-2-6-15)8-12(9)19-14(11)18/h3-4,7-8H,1-2,5-6H2,(H,16,17) AZGXIHFVKOMJRL-UHFFFAOYSA-N 50442702 CHEMBL2442511::US9296728, 26 Monocarboxylate transporter 1 380 ChEMBL 10.1016/j.bmcl.2016.05.054 10.7270/Q2BP04QP 27241692 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Ronayne, CT; Nelson, GL; Solano, LN; Lueth, EA; Drewes, LR; Mereddy, VR University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50442702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50442702&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667689 175455019 CHEMBL2442511 ZINC96286380 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50500625 OC(=O)c1cc2ccc(cc2oc1=O)N(Cc1ccccc1)Cc1ccccc1 InChI=1S/C24H19NO4/c26-23(27)21-13-19-11-12-20(14-22(19)29-24(21)28)25(15-17-7-3-1-4-8-17)16-18-9-5-2-6-10-18/h1-14H,15-16H2,(H,26,27) JRHSORWQTHPWJB-UHFFFAOYSA-N 214702 US9296728, 25 Monocarboxylate transporter 1 90 ChEMBL 10.1016/j.bmcl.2016.05.054 10.7270/Q2BP04QP 27241692 Gurrapu, S; Jonnalagadda, SK; Alam, MA; Ronayne, CT; Nelson, GL; Solano, LN; Lueth, EA; Drewes, LR; Mereddy, VR University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=214702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=214702&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 71667688 329965580 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50952612 Oc1cc(O)c2c(c1)oc(-c1ccc(O)c(O)c1)c(O)c2=O InChI=1S/C15H10O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,16-19,21H REFJWTPEDVJJIY-UHFFFAOYSA-N 7460 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one::2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromen-4-one::2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;hydrate::CHEMBL50::Quercetin::Quercetin (10)::Quercetin (21)::Quercetin (Qur)::US11021454, Compound Quercetin::US9180183, Quercetin::med.21724, Compound 4 Monocarboxylate transporter 1 14000 ChEMBL 10.1042/0264-6021:3410529 10.7270/Q2125TQV 10417314 Broer, S; Broer, A; Schneider, HP; Stegen, C; Halestrap, AP; Deitmer, JW Physiologisch-chemisches Institut der Eberhard-Karls-Universit£t T£bingen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=7460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=7460&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search QUE 3BPT,2HCK,3LJ0,4LMU,5FLI,5FLJ,3CF8,4DFU,4MRA,4WNJ,2O3P,2MS6,5AUW,3BXX,6M89,3LM5,1GP6,6AWS,6QCN,6QCD,7VUM,6B1D,2N6C,1E8W,2C9Z,5XG4,5A4V,2UXH,1H1I,2JJ2,6TTA,6IJD,3NVY 5280343 11108251 16243 CHEMBL50 DB04216 5346 C00389 ZINC03869685 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50952614 CCc1oc2ccccc2c1C(=O)c1cc(Br)c(O)c(Br)c1 InChI=1S/C17H12Br2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)17(21)12(19)8-9/h3-8,21H,2H2,1H3 WHQCHUCQKNIQEC-UHFFFAOYSA-N 50158460 (3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran-3-yl)methanone::2-ethyl-3-(3,5-dibrom-4-hydroxybenzoyl)benzofuran::3,5-dibromo-4-hydroxyphenyl-2-ethyl-3-benzofuranyl ketone::Benzbromarone::CHEMBL388590::US9725430, Compound 1::US9856239, benzbromarone::US9962362, Compound 1::Uroleap (TN)::cid_2333 Monocarboxylate transporter 1 22000 ChEMBL 10.1042/0264-6021:3410529 10.7270/Q2125TQV 10417314 Broer, S; Broer, A; Schneider, HP; Stegen, C; Halestrap, AP; Deitmer, JW Physiologisch-chemisches Institut der Eberhard-Karls-Universit£t T£bingen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158460&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search R75 7D6J,7ACU 2333 104045206 3023 CHEMBL388590 ZINC00608205 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50952616 Oc1ccc(CCC(=O)c2c(O)cc(O)cc2O)cc1 InChI=1S/C15H14O5/c16-10-4-1-9(2-5-10)3-6-12(18)15-13(19)7-11(17)8-14(15)20/h1-2,4-5,7-8,16-17,19-20H,3,6H2 VGEREEWJJVICBM-UHFFFAOYSA-N 23446 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one::CHEMBL45068::Phloretin::cid_4788 Monocarboxylate transporter 1 28000 ChEMBL 10.1042/0264-6021:3410529 10.7270/Q2125TQV 10417314 Broer, S; Broer, A; Schneider, HP; Stegen, C; Halestrap, AP; Deitmer, JW Physiologisch-chemisches Institut der Eberhard-Karls-Universit£t T£bingen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23446 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23446&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search G50 6L5S,6L5R,2UXI 4788 50091709 17276 CHEMBL45068 DB07810 4285 C00774 ZINC00047553 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 50952620 OC(=O)C(=C\c1ccc(O)cc1)\C#N InChI=1S/C10H7NO3/c11-6-8(10(13)14)5-7-1-3-9(12)4-2-7/h1-5,12H,(H,13,14)/b8-5+ AFVLVVWMAFSXCK-VMPITWQZSA-N 4350 (2E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enoic acid::benzylidenemalononitrile (BMN) deriv. 34 Monocarboxylate transporter 1 425000 ChEMBL 10.1042/0264-6021:3410529 10.7270/Q2125TQV 10417314 Broer, S; Broer, A; Schneider, HP; Stegen, C; Halestrap, AP; Deitmer, JW Physiologisch-chemisches Institut der Eberhard-Karls-Universit£t T£bingen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4350&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 5328791 8034027 64340 ZINC00155109 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 51505701 OC(=O)C(=C\c1ccc(O)cc1)\C#N InChI=1S/C10H7NO3/c11-6-8(10(13)14)5-7-1-3-9(12)4-2-7/h1-5,12H,(H,13,14)/b8-5+ AFVLVVWMAFSXCK-VMPITWQZSA-N 4350 (2E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enoic acid::benzylidenemalononitrile (BMN) deriv. 34 Monocarboxylate transporter 1 281 ChEMBL 10.7270/Q2M61QBT 34517305 Wang, Y; Qin, L; Chen, W; Chen, Q; Sun, J; Wang, G Guang Xi University of Chinese Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4350&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 5328791 8034027 64340 ZINC00155109 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 51505702 CC(C)c1ccc(\C=C(/C#N)C(O)=O)cc1 InChI=1S/C13H13NO2/c1-9(2)11-5-3-10(4-6-11)7-12(8-14)13(15)16/h3-7,9H,1-2H3,(H,15,16)/b12-7+ MFDAAQBTCZHEOT-KPKJPENVSA-N 50606661 CHEMBL5220706 Monocarboxylate transporter 1 66 ChEMBL 10.7270/Q2M61QBT 34517305 Wang, Y; Qin, L; Chen, W; Chen, Q; Sun, J; Wang, G Guang Xi University of Chinese Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50606661 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50606661&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 2461725 482617512 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 51505703 CC(C)Cn1c2sc(Cc3c(C)n[nH]c3C)c(C(=O)N3C[C@@H](O)CO3)c2c(=O)n(C)c1=O InChI=1S/C21H27N5O5S/c1-10(2)7-25-20-17(18(28)24(5)21(25)30)16(19(29)26-8-13(27)9-31-26)15(32-20)6-14-11(3)22-23-12(14)4/h10,13,27H,6-9H2,1-5H3,(H,22,23)/t13-/m1/s1 ISIVOJWVBJIOFM-CYBMUJFWSA-N 50606662 CHEMBL5221129 Monocarboxylate transporter 1 2.3 ChEMBL 10.7270/Q2M61QBT 34517305 Wang, Y; Qin, L; Chen, W; Chen, Q; Sun, J; Wang, G Guang Xi University of Chinese Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50606662 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50606662&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 156899746 482617513 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 51512102 OCCOc1ccc(\C=C(/C#N)C(O)=O)cc1 InChI=1S/C12H11NO4/c13-8-10(12(15)16)7-9-1-3-11(4-2-9)17-6-5-14/h1-4,7,14H,5-6H2,(H,15,16)/b10-7+ DAPMAHDYORYPJP-JXMROGBWSA-N 50608634 CHEMBL5280998 Monocarboxylate transporter 1 >5000 ChEMBL 10.7270/Q2P55SQC 32388280 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50608634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50608634&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 171353789 494498382 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 51512103 OC(=O)C(=C\c1ccc(OCCBr)cc1)\C#N InChI=1S/C12H10BrNO3/c13-5-6-17-11-3-1-9(2-4-11)7-10(8-14)12(15)16/h1-4,7H,5-6H2,(H,15,16)/b10-7+ MQIBBXQCRJJCQO-JXMROGBWSA-N 50608635 CHEMBL5268352 Monocarboxylate transporter 1 >5000 ChEMBL 10.7270/Q2P55SQC 32388280 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50608635 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50608635&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 171343398 494498383 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 51512104 CC(C)(C)[Si](Oc1ccc(\C=C(/C#N)C(O)=O)cc1)(c1ccccc1)c1ccccc1 InChI=1S/C26H25NO3Si/c1-26(2,3)31(23-10-6-4-7-11-23,24-12-8-5-9-13-24)30-22-16-14-20(15-17-22)18-21(19-27)25(28)29/h4-18H,1-3H3,(H,28,29)/b21-18+ ISJVSHIKNUAOEB-DYTRJAOYSA-N 50608636 CHEMBL5285345 Monocarboxylate transporter 1 408 ChEMBL 10.7270/Q2P55SQC 32388280 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50608636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50608636&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 171344712 494498384 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 51512105 CC(C)(C)[Si](OCCOc1ccc(\C=C(/C#N)C(O)=O)cc1)(c1ccccc1)c1ccccc1 InChI=1S/C28H29NO4Si/c1-28(2,3)34(25-10-6-4-7-11-25,26-12-8-5-9-13-26)33-19-18-32-24-16-14-22(15-17-24)20-23(21-29)27(30)31/h4-17,20H,18-19H2,1-3H3,(H,30,31)/b23-20+ RZNFGGZVNAMPLT-BSYVCWPDSA-N 50608637 CHEMBL5280660 Monocarboxylate transporter 1 97 ChEMBL 10.7270/Q2P55SQC 32388280 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50608637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50608637&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 171353089 494498385 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 51512106 OC(=O)C(=C\c1cn(-c2ccccc2)c2ccccc12)\C#N InChI=1S/C18H12N2O2/c19-11-13(18(21)22)10-14-12-20(15-6-2-1-3-7-15)17-9-5-4-8-16(14)17/h1-10,12H,(H,21,22)/b13-10+ BIZNHCWFGNKBBZ-JLHYYAGUSA-N 50608638 CHEMBL4303684 Monocarboxylate transporter 1 13 ChEMBL 10.7270/Q2P55SQC 32388280 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50608638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50608638&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 6438504 494498386 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 51512107 OC(=O)C(=C\c1cn(Cc2ccccc2)c2ccccc12)\C#N InChI=1S/C19H14N2O2/c20-11-15(19(22)23)10-16-13-21(12-14-6-2-1-3-7-14)18-9-5-4-8-17(16)18/h1-10,13H,12H2,(H,22,23)/b15-10+ PPKOZKHGVCZFNB-XNTDXEJSSA-N 50608639 CHEMBL4793546 Monocarboxylate transporter 1 66 ChEMBL 10.7270/Q2P55SQC 32388280 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50608639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50608639&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 137374807 494498387 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 51512108 OC(=O)C(=C\c1cn(-c2ccccn2)c2ccccc12)\C#N InChI=1S/C17H11N3O2/c18-10-12(17(21)22)9-13-11-20(16-7-3-4-8-19-16)15-6-2-1-5-14(13)15/h1-9,11H,(H,21,22)/b12-9+ PBSMJFLWDXXGJH-FMIVXFBMSA-N 50608640 CHEMBL5283025 Monocarboxylate transporter 1 >1000 ChEMBL 10.7270/Q2P55SQC 32388280 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50608640 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50608640&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 171356722 494498388 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987 51512109 CC(C)Cn1c2sc(Cc3c(C)n[nH]c3C)c(C(=O)N3C[C@@H](O)CO3)c2c(=O)n(C)c1=O InChI=1S/C21H27N5O5S/c1-10(2)7-25-20-17(18(28)24(5)21(25)30)16(19(29)26-8-13(27)9-31-26)15(32-20)6-14-11(3)22-23-12(14)4/h10,13,27H,6-9H2,1-5H3,(H,22,23)/t13-/m1/s1 ISIVOJWVBJIOFM-CYBMUJFWSA-N 50606662 CHEMBL5221129 Monocarboxylate transporter 1 2.0 ChEMBL 10.7270/Q2P55SQC 32388280 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50606662 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=9048&target=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50606662&enzyme=Monocarboxylate+transporter+1&column=ki&startPg=0&Increment=50&submit=Search 156899746 482617513 1 MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV Monocarboxylate transporter 1 MOT1_RAT P53987