BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 933293 NCCC#N InChI=1S/C3H6N2/c4-2-1-3-5/h1-2,4H2 AGSPXMVUFBBBMO-UHFFFAOYSA-N 50232678 CHEBI:27413::CHEMBL1618272::US10717734, Compound BAPN::US11098045, Compound BAPN Oxidized low-density lipoprotein receptor 1 >1000 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50232678 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50232678&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 1647 384583164 CHEMBL1618272 C05670 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933295 NC\C=C(/F)Cn1cc(-c2ccc(F)cc2)c2ccccc12 InChI=1S/C18H16F2N2/c19-14-7-5-13(6-8-14)17-12-22(11-15(20)9-10-21)18-4-2-1-3-16(17)18/h1-9,12H,10-11,21H2/b15-9- JPFSOENZKKNKEN-DHDCSXOGSA-N 454208 (Z)-3-fluoro-4-(3-(4-fluorophenyl)-1H- indol-1-yl)but-2-en-1-amine::US10717733, Compound 1::US11098045, Compound 1 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454208 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454208&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340972 440970088 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933297 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccccc12 InChI=1S/C21H24FN3O2S/c1-15-21(16-7-6-8-18(13-16)28(26,27)24(2)3)19-9-4-5-10-20(19)25(15)14-17(22)11-12-23/h4-11,13H,12,14,23H2,1-3H3/b17-11- FFWWSSGIANHKJO-BOPFTXTBSA-N 454209 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2-methyl-1H-indol-3-yl)-N,N- dimethylbenzenesulfonamide::US10717733, Compound 2::US11098045, Compound 2 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454209 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454209&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340971 440970089 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933299 CN(C)S(=O)(=O)c1ccc(cc1)-c1c(C)n(C\C(F)=C\CN)c2ccccc12 InChI=1S/C21H24FN3O2S/c1-15-21(16-8-10-18(11-9-16)28(26,27)24(2)3)19-6-4-5-7-20(19)25(15)14-17(22)12-13-23/h4-12H,13-14,23H2,1-3H3/b17-12- SVIHWIJPHXHIBN-ATVHPVEESA-N 454210 (Z)-4-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2-methyl-1H-indol-3-yl)-N,N- dimethylbenzenesulfonamide::US10717733, Compound 3::US11098045, Compound 3 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454210 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454210&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302638 440970090 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933301 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ncccc12 InChI=1S/C20H23FN4O2S/c1-14-19(15-6-4-7-17(12-15)28(26,27)24(2)3)18-8-5-11-23-20(18)25(14)13-16(21)9-10-22/h4-9,11-12H,10,13,22H2,1-3H3/b16-9- CFXHPCRZYKWUPK-SXGWCWSVSA-N 454211 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)- N,N-dimethylbenzenesulfonamide::US10717733, Compound 4::US11098045, Compound 4 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454211 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454211&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302811 440970091 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933303 COC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2c1 InChI=1S/C23H26FN3O4S/c1-15-22(16-6-5-7-19(12-16)32(29,30)26(2)3)20-13-17(23(28)31-4)8-9-21(20)27(15)14-18(24)10-11-25/h5-10,12-13H,11,14,25H2,1-4H3/b18-10- NRSYNKVPOCKDIH-ZDLGFXPLSA-N 454212 (Z)-methyl 1-(4-amino-2-fluorobut-2-en- 1-yl)-3-(3-N,N- dimethylsulfamoyl)phenyl)-2-methyl-1H- indole-5-carboxylate::US10717733, Compound 5::US11098045, Compound 5 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454212&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340289 440970092 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933305 CN(C)C(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2c1 InChI=1S/C24H29FN4O3S/c1-16-23(17-7-6-8-20(13-17)33(31,32)28(4)5)21-14-18(24(30)27(2)3)9-10-22(21)29(16)15-19(25)11-12-26/h6-11,13-14H,12,15,26H2,1-5H3/b19-11- NJTKSIQWDDYXEM-ODLFYWEKSA-N 454213 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)- N,N,2-trimethyl-1H-indole-5-carboxamide::US10717733, Compound 52::US10717733, Compound 6::US11098045, Compound 52 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454213&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302612 440970093 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933307 COC(=O)c1ccc2c(c(C)n(C\C(F)=C\CN)c2c1)-c1cccc(c1)S(=O)(=O)N(C)C InChI=1S/C23H26FN3O4S/c1-15-22(16-6-5-7-19(12-16)32(29,30)26(2)3)20-9-8-17(23(28)31-4)13-21(20)27(15)14-18(24)10-11-25/h5-10,12-13H,11,14,25H2,1-4H3/b18-10- CTWQNEGONIXSFR-ZDLGFXPLSA-N 454214 (Z)-methyl 1-(4-amino-2-fluorobut-2-en- 1-yl)-3-(3-(N,N- dimethylsulfamoyl)phenyl)-2-methyl-1H- indole-6-carboxylate::US10717733, Compound 7::US11098045, Compound 7 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454214 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454214&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340290 440970094 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933309 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O InChI=1S/C22H24FN3O4S/c1-14-21(15-5-4-6-18(11-15)31(29,30)25(2)3)19-12-16(22(27)28)7-8-20(19)26(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H,27,28)/b17-9- IAOICZAENMLTOU-MFOYZWKCSA-N 454215 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)-2- methyl-1H-indole-5-carboxylic acid::US10717733, Compound 8::US11098045, Compound 8 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454215 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454215&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302629 440970095 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933311 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2cc(ccc12)C(O)=O InChI=1S/C22H24FN3O4S/c1-14-21(15-5-4-6-18(11-15)31(29,30)25(2)3)19-8-7-16(22(27)28)12-20(19)26(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H,27,28)/b17-9- JKFARAGHJZMDQI-MFOYZWKCSA-N 454216 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)-2- methyl-1H-indole-6-carboxylic acid::US10717733, Compound 9::US11098045, Compound 9 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454216 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454216&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340717 440970096 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933313 CN(C)C(=O)c1ccc2c(c(C)n(C\C(F)=C\CN)c2c1)-c1cccc(c1)S(=O)(=O)N(C)C InChI=1S/C24H29FN4O3S/c1-16-23(17-7-6-8-20(13-17)33(31,32)28(4)5)21-10-9-18(24(30)27(2)3)14-22(21)29(16)15-19(25)11-12-26/h6-11,13-14H,12,15,26H2,1-5H3/b19-11- GJILSAQRIPFPDI-ODLFYWEKSA-N 454217 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)- N,N,2-trimethyl-1H-indole-6-carboxamide::US10717733, Compound 10::US11098045, Compound 10 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454217 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454217&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340719 440970097 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933315 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2cc(ccc12)C(N)=O InChI=1S/C22H25FN4O3S/c1-14-21(15-5-4-6-18(11-15)31(29,30)26(2)3)19-8-7-16(22(25)28)12-20(19)27(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H2,25,28)/b17-9- QUUGFFMFKSQZFN-MFOYZWKCSA-N 454218 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)-2- methyl-1H-indole-6-carboxamide::US10717733, Compound 11::US11098045, Compound 11 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454218 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454218&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340720 440970098 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933317 CCOC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2c1 InChI=1S/C24H28FN3O4S/c1-5-32-24(29)18-9-10-22-21(14-18)23(16(2)28(22)15-19(25)11-12-26)17-7-6-8-20(13-17)33(30,31)27(3)4/h6-11,13-14H,5,12,15,26H2,1-4H3/b19-11- HTLNQVKMQMVOPI-ODLFYWEKSA-N 454219 (Z)-ethyl 1-(4-amino-2-fluorobut-2-en-1- yl)-3-(3-(N,N-dimethylsulfamoyl)phenyl)- 2-methyl-1H-indole-5-carboxylate::US10717733, Compound 12::US11098045, Compound 12 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454219 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454219&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340718 440970099 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933319 CN(C)S(=O)(=O)c1cccc(-c2c(C)n(C\C(F)=C\CN)c3ccc(cc23)C(O)=O)c1C InChI=1S/C23H26FN3O4S/c1-14-18(6-5-7-21(14)32(30,31)26(3)4)22-15(2)27(13-17(24)10-11-25)20-9-8-16(23(28)29)12-19(20)22/h5-10,12H,11,13,25H2,1-4H3,(H,28,29)/b17-10- CZPQNEQWQQHYLE-YVLHZVERSA-N 454220 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)-2- methylphenyl)-2-methyl-1H-indole-5- carboxylic acid::US10717733, Compound 13::US11098045, Compound 13 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454220 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454220&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302746 440970100 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933321 Cc1c(-c2cccc(c2)S(C)(=O)=O)c2cc(ccc2n1C\C(F)=C\CN)C(O)=O InChI=1S/C21H21FN2O4S/c1-13-20(14-4-3-5-17(10-14)29(2,27)28)18-11-15(21(25)26)6-7-19(18)24(13)12-16(22)8-9-23/h3-8,10-11H,9,12,23H2,1-2H3,(H,25,26)/b16-8- XAABKVNXUAWXSU-PXNMLYILSA-N 454221 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-2- methyl-3-(3-(methylsulfonyl)phenyl)-1H- indole-5-carboxylic acid::US10717733, Compound 14::US11098045, Compound 14 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454221 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454221&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340281 440970101 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933323 CCOC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)C(=O)N(C)C)c2c1 InChI=1S/C25H28FN3O3/c1-5-32-25(31)19-9-10-22-21(14-19)23(16(2)29(22)15-20(26)11-12-27)17-7-6-8-18(13-17)24(30)28(3)4/h6-11,13-14H,5,12,15,27H2,1-4H3/b20-11- CKGAHBWUJAZHHP-JAIQZWGSSA-N 454222 (Z)-ethyl 1-(4-amino-2-fluorobut-2-en-1- yl)-3-(3-(dimethylcarbamoyl)phenyl)-2- methyl-1H-indole-5-carboxylate::US10717733, Compound 15::US11098045, Compound 15 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454222&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340280 440970102 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933325 CN(C)C(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O InChI=1S/C23H24FN3O3/c1-14-21(15-5-4-6-16(11-15)22(28)26(2)3)19-12-17(23(29)30)7-8-20(19)27(14)13-18(24)9-10-25/h4-9,11-12H,10,13,25H2,1-3H3,(H,29,30)/b18-9- KJKWDAGGVYNCGG-NVMNQCDNSA-N 454223 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(dimethylcarbamoyl)phenyl)-2-methyl- 1H-indole-5-carboxylic acid::US10717733, Compound 16::US11098045, Compound 16 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454223&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340282 440970103 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933327 CCOC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(C)(=O)=O)c2c1 InChI=1S/C23H25FN2O4S/c1-4-30-23(27)17-8-9-21-20(13-17)22(15(2)26(21)14-18(24)10-11-25)16-6-5-7-19(12-16)31(3,28)29/h5-10,12-13H,4,11,14,25H2,1-3H3/b18-10- HLBARMATWYKFAL-ZDLGFXPLSA-N 454224 (Z)-ethyl 1-(4-amino-2-fluorobut-2-en-1- yl)-2-methyl-3-(3- (methylsulfonyl)phenyl)-1H-indole-5- carboxylate::US10717733, Compound 17::US11098045, Compound 17 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454224 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454224&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340921 440970104 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933329 CNS(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O InChI=1S/C21H22FN3O4S/c1-13-20(14-4-3-5-17(10-14)30(28,29)24-2)18-11-15(21(26)27)6-7-19(18)25(13)12-16(22)8-9-23/h3-8,10-11,24H,9,12,23H2,1-2H3,(H,26,27)/b16-8- PCPBDUMNYRZIDJ-PXNMLYILSA-N 454225 (Z)-1-(4-amino-2-fluorobut-2-en-l-yl)-2- methyl-3-(3-(N-methylsulfamoyl)phenyl)- 1H-indole-5-carboxylic acid::US10717733, Compound 18::US11098045, Compound 18 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454225 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454225&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302574 440970105 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933331 CCOC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cc(ccc3C)S(=O)(=O)N(C)C)c2c1 InChI=1S/C25H30FN3O4S/c1-6-33-25(30)18-8-10-23-22(13-18)24(17(3)29(23)15-19(26)11-12-27)21-14-20(9-7-16(21)2)34(31,32)28(4)5/h7-11,13-14H,6,12,15,27H2,1-5H3/b19-11- AYOBNOKYKOMHDO-ODLFYWEKSA-N 454226 (Z)-ethyl 1-(4-amino-2-fluorobut-2-en-1- yl)-3-(5-(N,N-dimethylsulfamoyl)-2- methylphenyl)-2-methyl-1H-indole-5- carboxylate::US10717733, Compound 19::US11098045, Compound 19 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454226 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454226&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340922 440970106 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933333 CN(C)S(=O)(=O)c1ccc(C)c(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O InChI=1S/C23H26FN3O4S/c1-14-5-7-18(32(30,31)26(3)4)12-19(14)22-15(2)27(13-17(24)9-10-25)21-8-6-16(23(28)29)11-20(21)22/h5-9,11-12H,10,13,25H2,1-4H3,(H,28,29)/b17-9- CWGVGNOSBIENPA-MFOYZWKCSA-N 454227 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (5-(N,N-dimethylsulfamoyl)-2- methylphenyl)-2-methyl-1H-indole-5- carboxylic acid::US10717733, Compound 20::US11098045, Compound 20 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454227 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454227&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302751 440970107 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933335 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2cc(F)c(cc12)C(O)=O InChI=1S/C22H23F2N3O4S/c1-13-21(14-5-4-6-16(9-14)32(30,31)26(2)3)18-10-17(22(28)29)19(24)11-20(18)27(13)12-15(23)7-8-25/h4-7,9-11H,8,12,25H2,1-3H3,(H,28,29)/b15-7- FFTPACJQQYAFHN-CHHVJCJISA-N 454228 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)-6- fluoro-2-methyl-1H-indole-5-carboxylic acid::US10717733, Compound 21::US11098045, Compound 21 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454228 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454228&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340437 440970108 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933337 CCOC(=O)c1cc2c(c(C)n(C\C(F)=C\CN)c2cc1F)-c1cccc(c1)S(=O)(=O)N(C)C InChI=1S/C24H27F2N3O4S/c1-5-33-24(30)19-12-20-22(13-21(19)26)29(14-17(25)9-10-27)15(2)23(20)16-7-6-8-18(11-16)34(31,32)28(3)4/h6-9,11-13H,5,10,14,27H2,1-4H3/b17-9- CUXNKRROGVMNPP-MFOYZWKCSA-N 454229 (Z)-ethyl 1-(4-amino-2-fluorobut-2-en-1- yl)-3-(3-(N,N-dimethylsulfamoyl)phenyl)- 6-fluoro-2-methyl-1H-indole-5- carboxylate::US10717733, Compound 22::US11098045, Compound 22 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454229 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454229&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340435 440970109 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933339 Cc1c(-c2ccc(F)cc2)c2cc(ccc2n1C\C(F)=C\CN)C(O)=O InChI=1S/C20H18F2N2O2/c1-12-19(13-2-5-15(21)6-3-13)17-10-14(20(25)26)4-7-18(17)24(12)11-16(22)8-9-23/h2-8,10H,9,11,23H2,1H3,(H,25,26)/b16-8- LVTLXVHXXRMAAZ-PXNMLYILSA-N 454230 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (4-fluorophenyl)-2-methyl-1H-indole-5- carboxylic acid::US10717733, Compound 23::US11098045, Compound 23 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454230 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454230&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302717 440970110 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933341 CCOC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3ccc(F)cc3)c2c1 InChI=1S/C22H22F2N2O2/c1-3-28-22(27)16-6-9-20-19(12-16)21(15-4-7-17(23)8-5-15)14(2)26(20)13-18(24)10-11-25/h4-10,12H,3,11,13,25H2,1-2H3/b18-10- YDGMIZHGNYKRQY-ZDLGFXPLSA-N 454231 US10717733, Compound 24::US11098045, Compound 24::ethyl (Z)-1-(4-amino-2-fluorobut-2-en-1- yl)-3-(4-fluorophenyl)-2-methyl-1H- indole-5-carboxylate Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454231 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454231&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340436 440970111 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933343 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2cccnc12 InChI=1S/C20H23FN4O2S/c1-14-19(15-6-4-7-17(12-15)28(26,27)24(2)3)20-18(8-5-11-23-20)25(14)13-16(21)9-10-22/h4-9,11-12H,10,13,22H2,1-3H3/b16-9- YNYGVGYGPMQAEL-SXGWCWSVSA-N 454232 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2-methyl-1H-pyrrolo[3,2-b]pyridin-3-yl)- N,N-dimethylbenzenesulfonamide::US10717733, Compound 25::US11098045, Compound 25 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454232 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454232&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302687 440970112 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933345 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccncc12 InChI=1S/C20H23FN4O2S/c1-14-20(15-5-4-6-17(11-15)28(26,27)24(2)3)18-12-23-10-8-19(18)25(14)13-16(21)7-9-22/h4-8,10-12H,9,13,22H2,1-3H3/b16-7- NMIOMTWURASXJN-APSNUPSMSA-N 454233 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2-methyl-1H-pyrrolo[3,2-c]pyridin-3-yl- N,N-dimethylbenzenesulfonamide::US10717733, Compound 26::US11098045, Compound 26 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454233 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454233&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340434 440970113 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933347 CCOC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(Cl)c3)c2c1 InChI=1S/C22H22ClFN2O2/c1-3-28-22(27)16-7-8-20-19(12-16)21(15-5-4-6-17(23)11-15)14(2)26(20)13-18(24)9-10-25/h4-9,11-12H,3,10,13,25H2,1-2H3/b18-9- MTEAJOPQXXRPIV-NVMNQCDNSA-N 454234 US10717733, Compound 27::US11098045, Compound 27::ethyl (Z)-1-(4-amino-2-fluorobut-2-en-1- yl)-3-(3-chlorophenyl)-2-methyl-1H- indole-5-carboxylate Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454234 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454234&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340736 440970114 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933349 Cc1c(-c2cccc(Cl)c2)c2cc(ccc2n1C\C(F)=C\CN)C(O)=O InChI=1S/C20H18ClFN2O2/c1-12-19(13-3-2-4-15(21)9-13)17-10-14(20(25)26)5-6-18(17)24(12)11-16(22)7-8-23/h2-7,9-10H,8,11,23H2,1H3,(H,25,26)/b16-7- JPDKCTYHCKAPJF-APSNUPSMSA-N 454235 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-chlorophenyl)-2-methyl-1H-indole-5- carboxylic acid::US10717733, Compound 28::US11098045, Compound 28 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454235 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454235&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302758 440970115 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933351 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)-c1nn[nH]n1 InChI=1S/C22H24FN7O2S/c1-14-21(15-5-4-6-18(11-15)33(31,32)29(2)3)19-12-16(22-25-27-28-26-22)7-8-20(19)30(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H,25,26,27,28)/b17-9- HFXSXVBYINJBIZ-MFOYZWKCSA-N 454236 (Z)-3-(1-(4-amino-2-fluorobut-2-en-l-yl)- 2-methyl-5-(2H-tetrazol-5-yl)-1H-indol-3- yl)-N,N-dimethylbenzenesulfonamide::US10717733, Compound 29::US11098045, Compound 29 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454236 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454236&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302666 440970116 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933353 CCOC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)C(C)(C)C)c2c1 InChI=1S/C26H31FN2O2/c1-6-31-25(30)19-10-11-23-22(15-19)24(17(2)29(23)16-21(27)12-13-28)18-8-7-9-20(14-18)26(3,4)5/h7-12,14-15H,6,13,16,28H2,1-5H3/b21-12- KHWFSMWHXXFYJJ-MTJSOVHGSA-N 454237 US10717733, Compound 30::US11098045, Compound 30::ethyl (Z)-1-(4-amino-2-fluorobut-2-en-1- yl)-3-(3-(tert-butyl)phenyl)-2-methyl-1H- indole-5-carboxylate Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454237 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454237&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340809 440970117 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933355 Cc1c(-c2cccc(c2)C(C)(C)C)c2cc(ccc2n1C\C(F)=C\CN)C(O)=O InChI=1S/C24H27FN2O2/c1-15-22(16-6-5-7-18(12-16)24(2,3)4)20-13-17(23(28)29)8-9-21(20)27(15)14-19(25)10-11-26/h5-10,12-13H,11,14,26H2,1-4H3,(H,28,29)/b19-10- CSAVUFJECWFWKT-GRSHGNNSSA-N 454238 (Z)-1-(4-amino-2-fluorobut-2-en-l-yl)-3- (3-(tert-butyl)phenyl)-2-methyl-1H- indole-5-carboxylic acid::US10717733, Compound 31::US11098045, Compound 31 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454238 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454238&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340810 440970118 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933357 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2cnccc12 InChI=1S/C20H23FN4O2S/c1-14-20(15-5-4-6-17(11-15)28(26,27)24(2)3)18-8-10-23-12-19(18)25(14)13-16(21)7-9-22/h4-8,10-12H,9,13,22H2,1-3H3/b16-7- BKXMWBDHBUXWLZ-APSNUPSMSA-N 454239 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2-methyl-1H-pyrrolo[2,3-c]pyridin-3-yl)- N,N-dimethylbenzenesulfonamide::US10717733, Compound 32::US11098045, Compound 32 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454239 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454239&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302602 440970119 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933359 CCOC(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)S(=O)(=O)N(C)C InChI=1S/C24H28FN3O4S/c1-5-32-24(29)18-8-6-7-17(13-18)23-16(2)28(15-19(25)11-12-26)22-10-9-20(14-21(22)23)33(30,31)27(3)4/h6-11,13-14H,5,12,15,26H2,1-4H3/b19-11- NXNSCGDXGSAYPX-ODLFYWEKSA-N 454240 US10717733, Compound 33::US11098045, Compound 33::ethyl (Z)-3-(1-(4-amino-2-fluorobut-2-en- 1-yl)-5-(N,N-dimethylsulfamoyl)-2- methyl-1H-indol-3-yl)benzoate Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454240 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454240&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340811 440970120 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933361 CN(C)S(=O)(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)C(O)=O)c2c1 InChI=1S/C22H24FN3O4S/c1-14-21(15-5-4-6-16(11-15)22(27)28)19-12-18(31(29,30)25(2)3)7-8-20(19)26(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H,27,28)/b17-9- OAUNHIUUACPTIJ-MFOYZWKCSA-N 454241 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-(N,N-dimethylsulfamoyl)-2-methyl-1H- indol-3-yl)benzoic acid::US10717733, Compound 34::US11098045, Compound 34 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454241 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454241&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302631 440970121 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933363 CC(C)NC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2c1 InChI=1S/C25H31FN4O3S/c1-16(2)28-25(31)19-9-10-23-22(14-19)24(17(3)30(23)15-20(26)11-12-27)18-7-6-8-21(13-18)34(32,33)29(4)5/h6-11,13-14,16H,12,15,27H2,1-5H3,(H,28,31)/b20-11- LUKZWYDVODUKGO-JAIQZWGSSA-N 454242 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)-N- isopropyl-2-methyl-1H-indole-5- carboxamide::US10717733, Compound 35::US11098045, Compound 35 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454242 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454242&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302724 440970122 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933365 CC(C)N(C)C(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2c1 InChI=1S/C26H33FN4O3S/c1-17(2)30(6)26(32)20-10-11-24-23(15-20)25(18(3)31(24)16-21(27)12-13-28)19-8-7-9-22(14-19)35(33,34)29(4)5/h7-12,14-15,17H,13,16,28H2,1-6H3/b21-12- ISPGIAVPCFRBFX-MTJSOVHGSA-N 454243 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)-N- isopropyl-N,2-dimethyl-1H-indole-5- carboxamide::US10717733, Compound 36::US11098045, Compound 36 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454243 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454243&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302642 440970123 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933367 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(O)cc12 InChI=1S/C21H24FN3O3S/c1-14-21(15-5-4-6-18(11-15)29(27,28)24(2)3)19-12-17(26)7-8-20(19)25(14)13-16(22)9-10-23/h4-9,11-12,26H,10,13,23H2,1-3H3/b16-9- VMZRQLIVPKQUDC-SXGWCWSVSA-N 454244 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-hydroxy-2-methyl-1H-indol-3-yl)-N,N- dimethylbenzenesulfonamide::US10717733, Compound 37::US11098045, Compound 37 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454244 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454244&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302576 440970124 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933369 CN(c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O)S(C)(=O)=O InChI=1S/C22H24FN3O4S/c1-14-21(15-5-4-6-18(11-15)25(2)31(3,29)30)19-12-16(22(27)28)7-8-20(19)26(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H,27,28)/b17-9- AWHJWMCKUCEZQN-MFOYZWKCSA-N 454245 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-2- methyl-3-(3-(N- methylmethylsulfonamido)phenyl)-1H- indole-5-carboxylic acid::US10717733, Compound 38::US11098045, Compound 38 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454245 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454245&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340360 440970125 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933371 CN(C)C(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)N(C)S(C)(=O)=O)c2c1 InChI=1S/C24H29FN4O3S/c1-16-23(17-7-6-8-20(13-17)28(4)33(5,31)32)21-14-18(24(30)27(2)3)9-10-22(21)29(16)15-19(25)11-12-26/h6-11,13-14H,12,15,26H2,1-5H3/b19-11- VMMRBXSHHGEQJL-ODLFYWEKSA-N 454246 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)- N,N,2-trimethyl-3-(3-(N- methylmethylsulfonamido)phenyl)-1H- indole-5-carboxamide::US10717733, Compound 39::US11098045, Compound 39 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454246 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454246&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340361 440970126 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933373 CN(C)S(=O)(=O)c1cncc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O InChI=1S/C21H23FN4O4S/c1-13-20(15-8-17(11-24-10-15)31(29,30)25(2)3)18-9-14(21(27)28)4-5-19(18)26(13)12-16(22)6-7-23/h4-6,8-11H,7,12,23H2,1-3H3,(H,27,28)/b16-6- OFAYGIARESMFII-SOFYXZRVSA-N 454247 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (5-(N,N-dimethylsulfamoyl)pyridin-3-yl)- 2-methyl-1H-indole-5-carboxylic acid::US10717733, Compound 40::US11098045, Compound 40 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454247&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340661 440970127 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933375 CN(C)C(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cncc(c3)S(=O)(=O)N(C)C)c2c1 InChI=1S/C23H28FN5O3S/c1-15-22(17-10-19(13-26-12-17)33(31,32)28(4)5)20-11-16(23(30)27(2)3)6-7-21(20)29(15)14-18(24)8-9-25/h6-8,10-13H,9,14,25H2,1-5H3/b18-8- QYOGHIVVCYVEFQ-LSCVHKIXSA-N 454248 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (5-(N,N-dimethylsulfamoyl)pyridin-3-yl)- N,N,2-trimethyl-1H-indole-5-carboxamide::US10717733, Compound 41::US11098045, Compound 41 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454248 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454248&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130341090 440970128 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933377 CCOC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2n1 InChI=1S/C23H27FN4O4S/c1-5-32-23(29)19-9-10-20-22(26-19)21(15(2)28(20)14-17(24)11-12-25)16-7-6-8-18(13-16)33(30,31)27(3)4/h6-11,13H,5,12,14,25H2,1-4H3/b17-11- GPMKXMJMTMCLLA-BOPFTXTBSA-N 454249 (Z)-ethyl 1-(4-amino-2-fluorobut-2-en-1- yl)-3-(3-(N,N-dimethylsulfamoyl)phenyl- 2-methyl-1H-pyrrolo[3,2-b]pyridine-5- carboxylate::US10717733, Compound 42::US11098045, Compound 42 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454249 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454249&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340615 440970129 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933379 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(nc12)C(O)=O InChI=1S/C21H23FN4O4S/c1-13-19(14-5-4-6-16(11-14)31(29,30)25(2)3)20-18(8-7-17(24-20)21(27)28)26(13)12-15(22)9-10-23/h4-9,11H,10,12,23H2,1-3H3,(H,27,28)/b15-9- UORJLETWCVEPJY-DHDCSXOGSA-N 454250 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)-2- methyl-1H-pyrrolo[3,2-b]pyridine-5- carboxylic acid::US10717733, Compound 43::US11098045, Compound 43 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454250 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454250&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340616 440970130 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933381 CN(C)C(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2n1 InChI=1S/C23H28FN5O3S/c1-15-21(16-7-6-8-18(13-16)33(31,32)28(4)5)22-20(29(15)14-17(24)11-12-25)10-9-19(26-22)23(30)27(2)3/h6-11,13H,12,14,25H2,1-5H3/b17-11- ZCENNGVQLLWGOA-BOPFTXTBSA-N 454251 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)- N,N,2-trimethyl-1H-pyrrolo[3,2- b]pyridine-5-carboxamide::US10717733, Compound 44::US10717733, Compound 53::US11098045, Compound 53 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454251 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454251&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302714 440970131 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933383 CC(C)NC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2n1 InChI=1S/C24H30FN5O3S/c1-15(2)27-24(31)20-9-10-21-23(28-20)22(16(3)30(21)14-18(25)11-12-26)17-7-6-8-19(13-17)34(32,33)29(4)5/h6-11,13,15H,12,14,26H2,1-5H3,(H,27,31)/b18-11- NNNIZIIPUJHYKF-WQRHYEAKSA-N 454252 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)-N- isopropyl-2-methyl-1H-pyrrolo[3,2- b]pyridine-5-carboxamide::US10717733, Compound 45::US11098045, Compound 45 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454252 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454252&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302795 440970132 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933385 CNC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2n1 InChI=1S/C22H26FN5O3S/c1-14-20(15-6-5-7-17(12-15)32(30,31)27(3)4)21-19(28(14)13-16(23)10-11-24)9-8-18(26-21)22(29)25-2/h5-10,12H,11,13,24H2,1-4H3,(H,25,29)/b16-10- CNOSXHWIAUWTRO-YBEGLDIGSA-N 454253 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)-N,2- dimethyl-1H-pyrrolo[3,2-b]pyridine-5- carboxamide::US10717733, Compound 46::US11098045, Compound 46 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454253 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454253&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340386 440970133 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933387 CN(C)C(=O)c1cccc2c(c(C)n(C\C(F)=C\CN)c12)-c1cccc(c1)S(=O)(=O)N(C)C InChI=1S/C24H29FN4O3S/c1-16-22(17-8-6-9-19(14-17)33(31,32)28(4)5)20-10-7-11-21(24(30)27(2)3)23(20)29(16)15-18(25)12-13-26/h6-12,14H,13,15,26H2,1-5H3/b18-12- SNHOXOFEINYVMA-PDGQHHTCSA-N 454254 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)- N,N,2-trimethyl-1H-indole-7-carboxamide::US10717733, Compound 47::US11098045, Compound 47 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454254&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340383 440970134 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933389 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2c(cccc12)C(O)=O InChI=1S/C22H24FN3O4S/c1-14-20(15-6-4-7-17(12-15)31(29,30)25(2)3)18-8-5-9-19(22(27)28)21(18)26(14)13-16(23)10-11-24/h4-10,12H,11,13,24H2,1-3H3,(H,27,28)/b16-10- AEPLTXCPSKDZBR-YBEGLDIGSA-N 454255 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)-2- methyl-1H-indole-7-carboxylic acid::US10717733, Compound 48::US11098045, Compound 48 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454255 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454255&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340617 440970135 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933391 COc1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2c1 InChI=1S/C22H26FN3O3S/c1-15-22(16-6-5-7-19(12-16)30(27,28)25(2)3)20-13-18(29-4)8-9-21(20)26(15)14-17(23)10-11-24/h5-10,12-13H,11,14,24H2,1-4H3/b17-10- MMCWIOMFLQMOQR-YVLHZVERSA-N 454256 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-methoxy-2-methyl-1H-indol-3-yl)-N,N- dimethylbenzenesulfonamide::US10717733, Compound 49::US11098045, Compound 49 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454256&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340619 440970136 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933393 CN(C)C(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(C)(=O)=O)c2c1 InChI=1S/C23H26FN3O3S/c1-15-22(16-6-5-7-19(12-16)31(4,29)30)20-13-17(23(28)26(2)3)8-9-21(20)27(15)14-18(24)10-11-25/h5-10,12-13H,11,14,25H2,1-4H3/b18-10- VHQUEPCPKULQLT-ZDLGFXPLSA-N 454257 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)- N,N,2-trimethyl-3-(3- (methylsulfonyl)phenyl)-1H-indole-5- carboxamide::US10717733, Compound 50::US11098045, Compound 50 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454257&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340730 440970137 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933395 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C#N InChI=1S/C22H23FN4O2S/c1-15-22(17-5-4-6-19(12-17)30(28,29)26(2)3)20-11-16(13-25)7-8-21(20)27(15)14-18(23)9-10-24/h4-9,11-12H,10,14,24H2,1-3H3/b18-9- IDNUNCWRGCTLCS-NVMNQCDNSA-N 454258 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-cyano-2-methyl-1H-indol-3-yl)-N,N- dimethylbenzenesulfonamide::US10717733, Compound 51::US11098045, Compound 51 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454258 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454258&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302582 440970138 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933397 CN(C)C(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2c1 InChI=1S/C24H29FN4O3S/c1-16-23(17-7-6-8-20(13-17)33(31,32)28(4)5)21-14-18(24(30)27(2)3)9-10-22(21)29(16)15-19(25)11-12-26/h6-11,13-14H,12,15,26H2,1-5H3/b19-11- NJTKSIQWDDYXEM-ODLFYWEKSA-N 454213 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)- N,N,2-trimethyl-1H-indole-5-carboxamide::US10717733, Compound 52::US10717733, Compound 6::US11098045, Compound 52 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454213&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302612 440970093 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933399 CN(C)C(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2n1 InChI=1S/C23H28FN5O3S/c1-15-21(16-7-6-8-18(13-16)33(31,32)28(4)5)22-20(29(15)14-17(24)11-12-25)10-9-19(26-22)23(30)27(2)3/h6-11,13H,12,14,25H2,1-5H3/b17-11- ZCENNGVQLLWGOA-BOPFTXTBSA-N 454251 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)- N,N,2-trimethyl-1H-pyrrolo[3,2- b]pyridine-5-carboxamide::US10717733, Compound 44::US10717733, Compound 53::US11098045, Compound 53 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454251 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454251&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302714 440970131 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933401 CN(C)C(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(N)(=O)=O)c2c1 InChI=1S/C22H25FN4O3S/c1-14-21(15-5-4-6-18(11-15)31(25,29)30)19-12-16(22(28)26(2)3)7-8-20(19)27(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H2,25,29,30)/b17-9- CICGNEQHRCXYPB-MFOYZWKCSA-N 454261 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)- N,N,2-trimethyl-3-(3-sulfamoylphenyl)- 1H-indole-5-carboxamide::US10717733, Compound 54::US11098045, Compound 54 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454261 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454261&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302650 440970139 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933403 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)-c1ncon1 InChI=1S/C23H24FN5O3S/c1-15-22(16-5-4-6-19(11-16)33(30,31)28(2)3)20-12-17(23-26-14-32-27-23)7-8-21(20)29(15)13-18(24)9-10-25/h4-9,11-12,14H,10,13,25H2,1-3H3/b18-9- QSNLOFPNPBRZAJ-NVMNQCDNSA-N 454262 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2-methyl-5-(1,2,4-oxadiazol-3-yl)-1H- indol-3-yl)-N,N- dimethylbenzenesulfonamide::US10717733, Compound 55::US11098045, Compound 55 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454262 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454262&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302689 440970140 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933405 CN(C)C(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)C(F)(F)F)c2c1 InChI=1S/C23H23F4N3O/c1-14-21(15-5-4-6-17(11-15)23(25,26)27)19-12-16(22(31)29(2)3)7-8-20(19)30(14)13-18(24)9-10-28/h4-9,11-12H,10,13,28H2,1-3H3/b18-9- DLAGRBXZINHTKW-NVMNQCDNSA-N 454263 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)- N,N,2-trimethyl-3-(3- (trifluoromethyl)phenyl)-1H-indole-5- carboxamide::US10717733, Compound 56::US11098045, Compound 56 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454263 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454263&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340278 440970141 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933407 CN(C)C(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)C(F)(F)F)c2c1 InChI=1S/C23H23F4N3O3S/c1-14-21(15-5-4-6-18(11-15)34(32,33)23(25,26)27)19-12-16(22(31)29(2)3)7-8-20(19)30(14)13-17(24)9-10-28/h4-9,11-12H,10,13,28H2,1-3H3/b17-9- FEHDFLZXUYTLKR-MFOYZWKCSA-N 454264 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)- N,N,2-trimethyl-3-(3- ((trifluoromethyl)sulfonyl)phenyl)-1H- indole-5-carboxamide::US10717733, Compound 57::US11098045, Compound 57 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454264 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454264&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302645 440970142 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933409 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)S(=O)(=O)N(C)C InChI=1S/C23H29FN4O4S2/c1-16-23(17-7-6-8-19(13-17)33(29,30)26(2)3)21-14-20(34(31,32)27(4)5)9-10-22(21)28(16)15-18(24)11-12-25/h6-11,13-14H,12,15,25H2,1-5H3/b18-11- HZZNVSRPZUPPMJ-WQRHYEAKSA-N 454265 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)- N,N,2-trimethyl-1H-indole-5-sulfonamide::US10717733, Compound 58::US11098045, Compound 58 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454265 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454265&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340927 440970143 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933411 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(F)F InChI=1S/C22H24F3N3O2S/c1-14-21(15-5-4-6-18(11-15)31(29,30)27(2)3)19-12-16(22(24)25)7-8-20(19)28(14)13-17(23)9-10-26/h4-9,11-12,22H,10,13,26H2,1-3H3/b17-9- QAFDQOGRSXZVEP-MFOYZWKCSA-N 454266 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-(difluoromethyl)-2-methyl-1H-indol-3- yl)-N,N-dimethylbenzene-sulfonamide::US10717733, Compound 59::US11098045, Compound 59 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454266 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454266&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302565 440970144 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933413 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(O)nc12 InChI=1S/C20H23FN4O3S/c1-13-19(14-5-4-6-16(11-14)29(27,28)24(2)3)20-17(7-8-18(26)23-20)25(13)12-15(21)9-10-22/h4-9,11H,10,12,22H2,1-3H3,(H,23,26)/b15-9- RUJYRUBFVZJLCY-DHDCSXOGSA-N 454267 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-hydroxy-2-methyl-1H-pyrrolo[3,2- b]pyridin-3-yl)-N,N-dimethylbenzene- sulfonamide::US10717733, Compound 60::US11098045, Compound 60 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454267 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454267&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302546 440970145 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933415 COc1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2n1 InChI=1S/C21H25FN4O3S/c1-14-20(15-6-5-7-17(12-15)30(27,28)25(2)3)21-18(8-9-19(24-21)29-4)26(14)13-16(22)10-11-23/h5-10,12H,11,13,23H2,1-4H3/b16-10- GFVITOWSGPXAGC-YBEGLDIGSA-N 454268 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-methoxy-2-methyl-1H-pyrrolo[3,2- b]pyridin-3-yl)-N,N-dimethylbenzene- sulfonamide::US10717733, Compound 61::US11098045, Compound 61 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454268 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454268&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302708 440970146 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933417 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(Cl)cc12 InChI=1S/C21H23ClFN3O2S/c1-14-21(15-5-4-6-18(11-15)29(27,28)25(2)3)19-12-16(22)7-8-20(19)26(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3/b17-9- GDLVXWLFNXIEER-MFOYZWKCSA-N 454269 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-chloro-2-methyl-1H-indol-3-yl)-N,N- dimethylbenzenesulfonamide::US10717733, Compound 62::US11098045, Compound 62 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454269 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454269&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302766 440970147 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933419 CN(C)S(=O)(=O)c1cncc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccccc12 InChI=1S/C20H23FN4O2S/c1-14-20(15-10-17(12-23-11-15)28(26,27)24(2)3)18-6-4-5-7-19(18)25(14)13-16(21)8-9-22/h4-8,10-12H,9,13,22H2,1-3H3/b16-8- YRTJAKHAIIIFHD-PXNMLYILSA-N 454270 (Z)-5-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2-methyl-1H-indol-3-yl)-N,N- dimethylpyridine-3-sulfonamide::US10717733, Compound 63::US11098045, Compound 63 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454270 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454270&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302695 440970148 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933421 CN(C)S(=O)(=O)c1cncc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(Cl)cc12 InChI=1S/C20H22ClFN4O2S/c1-13-20(14-8-17(11-24-10-14)29(27,28)25(2)3)18-9-15(21)4-5-19(18)26(13)12-16(22)6-7-23/h4-6,8-11H,7,12,23H2,1-3H3/b16-6- YJGKFXFYARFULF-SOFYXZRVSA-N 454271 (Z)-5-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-chloro-2-methyl-1H-indol-3-yl)-N,N- dimethylpyridine-3-sulfonamide::US10717733, Compound 64::US11098045, Compound 64 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454271 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454271&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302671 440970149 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933423 Cc1c(-c2cncc(c2)S(C)(=O)=O)c2cc(Cl)ccc2n1C\C(F)=C\CN InChI=1S/C19H19ClFN3O2S/c1-12-19(13-7-16(10-23-9-13)27(2,25)26)17-8-14(20)3-4-18(17)24(12)11-15(21)5-6-22/h3-5,7-10H,6,11,22H2,1-2H3/b15-5- LYXQDOCFRZPEMI-WCSRMQSCSA-N 454272 (Z)-4-(5-chloro-2-methyl-3-(5- (methylsulfonyl)pyridin-3-yl)-1H-indol-1- yl)-3-fluorobut-2-en-1-amine::US10717733, Compound 65::US11098045, Compound 65 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454272 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454272&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340721 440970150 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933425 CN(C)S(=O)(=O)c1cncc(c1)-c1cn(C\C(F)=C\CN)c2ccc(Cl)cc12 InChI=1S/C19H20ClFN4O2S/c1-24(2)28(26,27)16-7-13(9-23-10-16)18-12-25(11-15(21)5-6-22)19-4-3-14(20)8-17(18)19/h3-5,7-10,12H,6,11,22H2,1-2H3/b15-5- IPTVKPDQJDWFRX-WCSRMQSCSA-N 454273 (Z)-5-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-chloro-1H-indol-3-yl)-N,N- dimethylpyridine-3-sulfonamide::US10717733, Compound 66::US11098045, Compound 66 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454273 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454273&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302693 440970151 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933427 CN(C)S(=O)(=O)c1cncc(c1)-c1c(C)n(C\C(F)=C\CN)c2cc(Cl)ccc12 InChI=1S/C20H22ClFN4O2S/c1-13-20(14-8-17(11-24-10-14)29(27,28)25(2)3)18-5-4-15(21)9-19(18)26(13)12-16(22)6-7-23/h4-6,8-11H,7,12,23H2,1-3H3/b16-6- WMRDUKQHVNVGMA-SOFYXZRVSA-N 454274 (Z)-5-(1-(4-amino-2-fluorobut-2-en-l-yl)- 6-chloro-2-methyl-1H-indol-3-yl)-N,N- dimethylpyridine-3-sulfonamide::US10717733, Compound 67::US11098045, Compound 67 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454274 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454274&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302614 440970152 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933429 COc1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(SC)c3)c2n1 InChI=1S/C20H22FN3OS/c1-13-19(14-5-4-6-16(11-14)26-3)20-17(7-8-18(23-20)25-2)24(13)12-15(21)9-10-22/h4-9,11H,10,12,22H2,1-3H3/b15-9- KMSZGJIQCLEWBE-DHDCSXOGSA-N 454275 (Z)-3-fluoro-4-(5-methoxy-2-methyl-3-(3- (methylthio)phenyl)-1H-pyrrolo[3,2- b]pyridin-1-yl)but-2-en-1-amine::US10717733, Compound 68::US11098045, Compound 68 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454275 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454275&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340813 440970153 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933431 COc1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(C)(=O)=O)c2n1 InChI=1S/C20H22FN3O3S/c1-13-19(14-5-4-6-16(11-14)28(3,25)26)20-17(7-8-18(23-20)27-2)24(13)12-15(21)9-10-22/h4-9,11H,10,12,22H2,1-3H3/b15-9- LONHJBOQCASDGC-DHDCSXOGSA-N 454276 (Z)-3-fluoro-4-(5-methoxy-2-methyl-3-(3- (methylsulfonyl)phenyl)-1H-pyrrolo[3,2- b]pyridin-1-yl)but-2-en-1-amine::US10717733, Compound 69::US11098045, Compound 69 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454276 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454276&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340812 440970154 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933433 CNS(=O)(=O)c1cncc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(Cl)cc12 InChI=1S/C19H20ClFN4O2S/c1-12-19(13-7-16(10-24-9-13)28(26,27)23-2)17-8-14(20)3-4-18(17)25(12)11-15(21)5-6-22/h3-5,7-10,23H,6,11,22H2,1-2H3/b15-5- AIRDSXKULYLFHT-WCSRMQSCSA-N 454277 (Z)-5-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-chloro-2-methyl-1H-indol-3-yl)-N- methylpyridine-3-sulfonamide::US10717733, Compound 70::US11098045, Compound 70 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454277 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454277&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302737 440970155 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933435 CN(C)S(=O)(=O)c1cncc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(F)cc12 InChI=1S/C20H22F2N4O2S/c1-13-20(14-8-17(11-24-10-14)29(27,28)25(2)3)18-9-15(21)4-5-19(18)26(13)12-16(22)6-7-23/h4-6,8-11H,7,12,23H2,1-3H3/b16-6- VGFSHMFFCDJALG-SOFYXZRVSA-N 454278 (Z)-5-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-fluoro-2-methyl-1H-indol-3-yl)-N,N- dimethylpyridine-3-sulfonamide::US10717733, Compound 71::US11098045, Compound 71 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454278 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454278&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130341152 440970156 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933437 CN(C)S(=O)(=O)c1cncc(c1)-c1c(C)n(C\C(F)=C\CN)c2cc(Cl)cnc12 InChI=1S/C19H21ClFN5O2S/c1-12-18(13-6-16(10-23-8-13)29(27,28)25(2)3)19-17(7-14(20)9-24-19)26(12)11-15(21)4-5-22/h4,6-10H,5,11,22H2,1-3H3/b15-4- SBPPRHMQFPOAQA-TVPGTPATSA-N 454279 (Z)-5-(1-(4-amino-2-fluorobut-2-en-1-yl)- 6-chloro-2-methyl-1H-pyrrolo[3,2- b]pyridin-3-yl)-N,N-dimethylpyridine-3- sulfonamide::US10717733, Compound 72::US11098045, Compound 72 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454279 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454279&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130341153 440970157 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933439 CN(C)S(=O)(=O)c1cncc(c1)-c1c(C)n(C\C(F)=C\CN)c2ncc(Cl)cc12 InChI=1S/C19H21ClFN5O2S/c1-12-18(13-6-16(10-23-8-13)29(27,28)25(2)3)17-7-14(20)9-24-19(17)26(12)11-15(21)4-5-22/h4,6-10H,5,11,22H2,1-3H3/b15-4- BAHGGRQZWUCPLS-TVPGTPATSA-N 454280 (Z)-5-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-chloro-2-methyl-1H-pyrrolo[2,3- b]pyridin-3-yl)-N,N-dimethylpyridine-3- sulfonamide::US10717733, Compound 73::US11098045, Compound 73 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454280 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454280&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130341151 440970158 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933441 CN(C)S(=O)(=O)c1cncc(c1)-c1c(C)n(C\C(F)=C\CN)c2c(Cl)cccc12 InChI=1S/C20H22ClFN4O2S/c1-13-19(14-9-16(11-24-10-14)29(27,28)25(2)3)17-5-4-6-18(21)20(17)26(13)12-15(22)7-8-23/h4-7,9-11H,8,12,23H2,1-3H3/b15-7- DMQBNXWLVZYSHY-CHHVJCJISA-N 454281 (Z)-5-(1-(4-amino-2-fluorobut-2-en-1-yl)- 7-chloro-2-methyl-1H-indol-3-yl)-N,N- dimethylpyridine-3-sulfonamide::US10717733, Compound 74::US11098045, Compound 74 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454281 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454281&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302749 440970159 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933443 CN(C)S(=O)(=O)c1cncc(c1)-c1c(C)n(C\C(F)=C\CN)c2cccc(Cl)c12 InChI=1S/C20H22ClFN4O2S/c1-13-19(14-9-16(11-24-10-14)29(27,28)25(2)3)20-17(21)5-4-6-18(20)26(13)12-15(22)7-8-23/h4-7,9-11H,8,12,23H2,1-3H3/b15-7- BGUIUILVCOCCOJ-CHHVJCJISA-N 454282 (Z)-5-(1-(4-amino-2-fluorobut-2-en-1-yl)- 4-chloro-2-methyl-1H-indol-3-yl)-N,N- dimethylpyridine-3-sulfonamide::US10717733, Compound 75::US11098045, Compound 75 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454282 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454282&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302604 440970160 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933445 Cc1c(-c2ccncc2)c2cc(Cl)ccc2n1C\C(F)=C\CN InChI=1S/C18H17ClFN3/c1-12-18(13-5-8-22-9-6-13)16-10-14(19)2-3-17(16)23(12)11-15(20)4-7-21/h2-6,8-10H,7,11,21H2,1H3/b15-4- RTJBWWUDJSWTAR-TVPGTPATSA-N 454283 (Z)-4-(5-chloro-2-methyl-3-(pyridin-4-yl)- 1H-indol-1-yl)-3-fluorobut-2-en-1-amine::US10717733, Compound 76::US11098045, Compound 76 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454283 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454283&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340808 440970161 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933447 Cc1c(-c2cccnc2)c2cc(Cl)ccc2n1C\C(F)=C\CN InChI=1S/C18H17ClFN3/c1-12-18(13-3-2-8-22-10-13)16-9-14(19)4-5-17(16)23(12)11-15(20)6-7-21/h2-6,8-10H,7,11,21H2,1H3/b15-6- RMTFSHKGTBCWAW-UUASQNMZSA-N 454284 (Z)-4-(5-chloro-2-methyl-3-(pyridin-3-yl)- 1H-indol-1-yl)-3-fluorobut-2-en-1-amine::US10717733, Compound 77::US11098045, Compound 77 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454284 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454284&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302625 440970162 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933449 CN(C)S(=O)(=O)c1cccc(n1)-c1c(C)n(C\C(F)=C\CN)c2ccc(Cl)cc12 InChI=1S/C20H22ClFN4O2S/c1-13-20(17-5-4-6-19(24-17)29(27,28)25(2)3)16-11-14(21)7-8-18(16)26(13)12-15(22)9-10-23/h4-9,11H,10,12,23H2,1-3H3/b15-9- HRGFULBVHRNBTG-DHDCSXOGSA-N 454285 (Z)-6-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-chloro-2-methyl-1H-indol-3-yl)-N,N- dimethylpyridine-2-sulfonamide::US10717733, Compound 78::US11098045, Compound 78 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454285 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454285&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302730 440970163 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933451 CN(C)S(=O)(=O)c1cncc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C1CC1 InChI=1S/C23H27FN4O2S/c1-15-23(18-10-20(13-26-12-18)31(29,30)27(2)3)21-11-17(16-4-5-16)6-7-22(21)28(15)14-19(24)8-9-25/h6-8,10-13,16H,4-5,9,14,25H2,1-3H3/b19-8- WRZUTJXQDIEVCW-UWVJOHFNSA-N 454286 (Z)-5-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-cyclopropyl-2-methyl-1H-indol-3-yl)- N,N-dimethylpyridine-3-sulfonamide::US10717733, Compound 79::US11098045, Compound 79 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454286 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454286&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302778 440970164 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933453 Cc1c(-c2cncnc2)c2cc(Cl)ccc2n1C\C(F)=C\CN InChI=1S/C17H16ClFN4/c1-11-17(12-7-21-10-22-8-12)15-6-13(18)2-3-16(15)23(11)9-14(19)4-5-20/h2-4,6-8,10H,5,9,20H2,1H3/b14-4- PBOOZGOWDGVWFI-CPSFFCFKSA-N 454287 (Z)-4-(5-chloro-2-methyl-3-(pyrimidin-5- yl)-1H-indol-1-yl)-3-fluorobut-2-en-1- amine::US10717733, Compound 80::US11098045, Compound 80 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454287 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454287&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302636 440970165 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933455 CN(C)S(=O)(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3ccncc3)c2c1 InChI=1S/C20H23FN4O2S/c1-14-20(15-7-10-23-11-8-15)18-12-17(28(26,27)24(2)3)4-5-19(18)25(14)13-16(21)6-9-22/h4-8,10-12H,9,13,22H2,1-3H3/b16-6- OZLSSHJXSURSTI-SOFYXZRVSA-N 454288 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)- N,N,2-trimethyl-3-(pyridin-4-yl)-1H- indole-5-sulfonamide::US10717733, Compound 81::US11098045, Compound 81 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454288 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454288&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302643 440970166 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933457 CN(C)S(=O)(=O)c1ccc(C)c(c1)-c1c(C)n(C\C(F)=C\CN)c2c(F)cc(Cl)cc12 InChI=1S/C22H24ClF2N3O2S/c1-13-5-6-17(31(29,30)27(3)4)11-18(13)21-14(2)28(12-16(24)7-8-26)22-19(21)9-15(23)10-20(22)25/h5-7,9-11H,8,12,26H2,1-4H3/b16-7- PUUTWSFCFSHISQ-APSNUPSMSA-N 454289 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-chloro-7-fluoro-2-methyl-1H-indol-3- yl)-N,N,4-trimethylbenzenesulfonamide::US10717733, Compound 82::US11098045, Compound 82 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454289&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302722 440970167 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933459 Cc1c(-c2cncc(c2)S(N)(=O)=O)c2cc(Cl)ccc2n1C\C(F)=C\CN InChI=1S/C18H18ClFN4O2S/c1-11-18(12-6-15(9-23-8-12)27(22,25)26)16-7-13(19)2-3-17(16)24(11)10-14(20)4-5-21/h2-4,6-9H,5,10,21H2,1H3,(H2,22,25,26)/b14-4- ALOYLRIYXMBLRE-CPSFFCFKSA-N 454290 (Z)-5-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-chloro-2-methyl-1H-indol-3- yl)pyridine-3-sulfonamide::US10717733, Compound 83::US11098045, Compound 83 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454290&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302607 440970168 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933461 Cc1c(-c2ccncc2)c2cc(ccc2n1C\C(F)=C\CN)S(N)(=O)=O InChI=1S/C18H19FN4O2S/c1-12-18(13-5-8-22-9-6-13)16-10-15(26(21,24)25)2-3-17(16)23(12)11-14(19)4-7-20/h2-6,8-10H,7,11,20H2,1H3,(H2,21,24,25)/b14-4- DIOYUFSKSAVHOY-CPSFFCFKSA-N 454291 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-2- methyl-3-(pyridin-4-yl)-1H-indole-5- sulfonamide::US10717733, Compound 84::US11098045, Compound 84 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454291 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454291&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130341091 440970169 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933463 CN(C)S(=O)(=O)c1cncc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(OC(F)(F)F)cc12 InChI=1S/C21H22F4N4O3S/c1-13-20(14-8-17(11-27-10-14)33(30,31)28(2)3)18-9-16(32-21(23,24)25)4-5-19(18)29(13)12-15(22)6-7-26/h4-6,8-11H,7,12,26H2,1-3H3/b15-6- QHPTXOQKFWZNAU-UUASQNMZSA-N 454292 (Z)-5-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2-methyl-5-(trifluoromethoxy)-1H-indol- 3-yl)-N,N-dimethylpyridine-3- sulfonamide::US10717733, Compound 85::US11098045, Compound 85 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454292 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454292&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340694 440970170 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933465 CN(C)S(=O)(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3ccccc3)c2c1 InChI=1S/C21H24FN3O2S/c1-15-21(16-7-5-4-6-8-16)19-13-18(28(26,27)24(2)3)9-10-20(19)25(15)14-17(22)11-12-23/h4-11,13H,12,14,23H2,1-3H3/b17-11- PAEBSSCCJBOUPY-BOPFTXTBSA-N 454293 (Z,)-1-(4-amino-2-fluorobut-2-en-1-yl)- N,N,2-trimethyl-3-phenyl-1H-indole-5- sulfonamide::US10717733, Compound 86::US11098045, Compound 86 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454293&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 140959835 440970171 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933467 Cc1c(-c2ccccc2)c2cc(ccc2n1C\C(F)=C\CN)S(C)(=O)=O InChI=1S/C20H21FN2O2S/c1-14-20(15-6-4-3-5-7-15)18-12-17(26(2,24)25)8-9-19(18)23(14)13-16(21)10-11-22/h3-10,12H,11,13,22H2,1-2H3/b16-10- VVUZMZSGTNBEMW-YBEGLDIGSA-N 454294 (Z)-3-fluoro-4-(2-methyl-5- (methylsulfonyl)-3-phenyl-1H-indol-1- yl)but-2-en-1-amine::US10717733, Compound 87::US11098045, Compound 87 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454294 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454294&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302599 440970172 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933469 Cc1c(-c2ccncc2)c2cc(ccc2n1C\C(F)=C\CN)S(C)(=O)=O InChI=1S/C19H20FN3O2S/c1-13-19(14-6-9-22-10-7-14)17-11-16(26(2,24)25)3-4-18(17)23(13)12-15(20)5-8-21/h3-7,9-11H,8,12,21H2,1-2H3/b15-5- RKIUZNHFBMWLKB-WCSRMQSCSA-N 454295 (Z)-3-fluoro-4-(2-methyl-5- (methylsulfonyl)-3-(pyridin-4-yl)-1H- indol-1-yl)but-2-en-1-amine::US10717733, Compound 88::US11098045, Compound 88 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454295 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454295&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340618 440970173 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933471 Cc1c(-c2cc(C)nc(C)c2)c2cc(ccc2n1C\C(F)=C\CN)S(C)(=O)=O InChI=1S/C21H24FN3O2S/c1-13-9-16(10-14(2)24-13)21-15(3)25(12-17(22)7-8-23)20-6-5-18(11-19(20)21)28(4,26)27/h5-7,9-11H,8,12,23H2,1-4H3/b17-7- YXVDHWKOLDGTAF-IDUWFGFVSA-N 454296 (Z)-4-(3-(2,6-dimethylpyridin-4-yl)-2- methyl-5-(methylsulfonyl)-1H-indol-1- yl)-3-fluorobut-2-en-1-amine::US10717733, Compound 89::US11098045, Compound 89 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454296&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302706 440970174 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933473 CN(C)C(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cc(C)nc(C)c3)c2c1 InChI=1S/C23H27FN4O/c1-14-10-18(11-15(2)26-14)22-16(3)28(13-19(24)8-9-25)21-7-6-17(12-20(21)22)23(29)27(4)5/h6-8,10-12H,9,13,25H2,1-5H3/b19-8- JNYPGWNXROHHDU-UWVJOHFNSA-N 454297 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (2,6-dimethylpyridin-4-yl)-N,N,2- trimethyl-1H-indole-5-carboxamide::US10717733, Compound 90::US11098045, Compound 90 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454297 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454297&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302718 440970175 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933475 Cc1c(-c2ccncc2)c2cc(ccc2n1C\C(F)=C\CN)C(=O)NC(C)(C)C InChI=1S/C23H27FN4O/c1-15-21(16-8-11-26-12-9-16)19-13-17(22(29)27-23(2,3)4)5-6-20(19)28(15)14-18(24)7-10-25/h5-9,11-13H,10,14,25H2,1-4H3,(H,27,29)/b18-7- HNUNUFDNZBBBMV-WSVATBPTSA-N 454298 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-N- (tert-butyl)-2-methyl-3-(pyridin-4-yl)-1H- indole-5-carboxamide::US10717733, Compound 91::US11098045, Compound 91 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454298 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454298&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302679 440970176 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933477 Cc1c(-c2ccc3OCOc3c2)c2cc(ccc2n1C\C(F)=C\CN)S(C)(=O)=O InChI=1S/C21H21FN2O4S/c1-13-21(14-3-6-19-20(9-14)28-12-27-19)17-10-16(29(2,25)26)4-5-18(17)24(13)11-15(22)7-8-23/h3-7,9-10H,8,11-12,23H2,1-2H3/b15-7- NZCZZVYLRXZCSO-CHHVJCJISA-N 454299 (Z)-4-(3-(benzo[d][1,3]dioxol-5-yl)-2- methyl-5-(methylsulfonyl)-1H-indol-1- yl)-3-fluorobut-2-en-1-amine::US10717733, Compound 92::US11098045, Compound 92 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454299&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340975 440970177 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933479 Cc1c(-c2ccc(F)cc2)c2cc(ccc2n1C\C(F)=C\CN)S(C)(=O)=O InChI=1S/C20H20F2N2O2S/c1-13-20(14-3-5-15(21)6-4-14)18-11-17(27(2,25)26)7-8-19(18)24(13)12-16(22)9-10-23/h3-9,11H,10,12,23H2,1-2H3/b16-9- QVVSHBGWCLBQFS-SXGWCWSVSA-N 454300 (Z)-3-fluoro-4-(3-(4-fluorophenyl)-2- methyl-5-(methylsulfonyl)-1H-indol-1- yl)but-2-en-1-amine::US10717733, Compound 93::US11098045, Compound 93 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454300 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454300&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340381 440970178 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933481 Cc1c(-c2ccnc(C)c2)c2cc(ccc2n1C\C(F)=C\CN)S(C)(=O)=O InChI=1S/C20H22FN3O2S/c1-13-10-15(7-9-23-13)20-14(2)24(12-16(21)6-8-22)19-5-4-17(11-18(19)20)27(3,25)26/h4-7,9-11H,8,12,22H2,1-3H3/b16-6- QWPMTVONEHGSQW-SOFYXZRVSA-N 454301 (Z)-3-fluoro-4-(2-methyl-3-(2- methylpyridin-4-yl)-5-(methylsulfonyl)- 1H-indol-1-yl)but-2-en-l-amine::US10717733, Compound 94::US11098045, Compound 94 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454301 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454301&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340382 440970179 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933483 Cc1c(-c2ccc(F)cc2)c2cc(ccc2n1C\C(F)=C\CN)S(N)(=O)=O InChI=1S/C19H19F2N3O2S/c1-12-19(13-2-4-14(20)5-3-13)17-10-16(27(23,25)26)6-7-18(17)24(12)11-15(21)8-9-22/h2-8,10H,9,11,22H2,1H3,(H2,23,25,26)/b15-8- PPAMXDACGNFUAY-NVNXTCNLSA-N 454302 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (4-fluorophenyl)-2-methyl-1H-indole-5- sulfonamide::US10717733, Compound 95::US11098045, Compound 95 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454302 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454302&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340380 440970180 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933485 CN(C)S(=O)(=O)c1cncc(c1)-c1c(Cl)n(C\C(F)=C\CN)c2ccccc12 InChI=1S/C19H20ClFN4O2S/c1-24(2)28(26,27)15-9-13(10-23-11-15)18-16-5-3-4-6-17(16)25(19(18)20)12-14(21)7-8-22/h3-7,9-11H,8,12,22H2,1-2H3/b14-7- YZFJULKNOVCHHD-AUWJEWJLSA-N 454303 (Z)-5-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2-chloro-1H-indol-3-yl)-N,N- dimethylpyridine-3-sulfonamide::US10717733, Compound 96::US11098045, Compound 96 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454303 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454303&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302673 440970181 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933487 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)S(C)(=O)=O InChI=1S/C22H26FN3O4S2/c1-15-22(16-6-5-7-19(12-16)32(29,30)25(2)3)20-13-18(31(4,27)28)8-9-21(20)26(15)14-17(23)10-11-24/h5-10,12-13H,11,14,24H2,1-4H3/b17-10- WIUGYCXDLGMJMM-YVLHZVERSA-N 454304 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2-methyl-5-(methylsulfonyl)-1H-indol-3- yl)-N,N-dimethylbenzenesulfonamide::US10717733, Compound 97::US11098045, Compound 97 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454304 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454304&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340283 440970182 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933489 COc1cc(ccn1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)S(C)(=O)=O InChI=1S/C20H22FN3O3S/c1-13-20(14-7-9-23-19(10-14)27-2)17-11-16(28(3,25)26)4-5-18(17)24(13)12-15(21)6-8-22/h4-7,9-11H,8,12,22H2,1-3H3/b15-6- ZVNJXJYCLKMNIS-UUASQNMZSA-N 454305 (Z)-3-fluoro-4-(3-(2-methoxypyridin-4- yl)-2-methyl-5-(methylsulfonyl)-1H- indol-1-yl)but-2-en-1-amine::US10717733, Compound 98::US11098045, Compound 98 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454305 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454305&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340284 440970183 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933491 CN(C)S(=O)(=O)c1cccc(c1)-c1c(Cl)n(C\C(F)=C\CN)c2cccnc12 InChI=1S/C19H20ClFN4O2S/c1-24(2)28(26,27)15-6-3-5-13(11-15)17-18-16(7-4-10-23-18)25(19(17)20)12-14(21)8-9-22/h3-8,10-11H,9,12,22H2,1-2H3/b14-8- YJIHEXTWFQRSBT-ZSOIEALJSA-N 454306 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2-chloro-1H-pyrrolo[3,2-b]pyridin-3-yl)- N,N-dimethylbenzenesulfonamide::US10717733, Compound 99::US11098045, Compound 99 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454306 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454306&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302627 440970184 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933493 CN(C)S(=O)(=O)c1cccc(c1)-c1c(Cl)n(C\C(F)=C\CN)c2ccc(cc12)S(C)(=O)=O InChI=1S/C21H23ClFN3O4S2/c1-25(2)32(29,30)17-6-4-5-14(11-17)20-18-12-16(31(3,27)28)7-8-19(18)26(21(20)22)13-15(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3/b15-9- PPSPBSQSGKQUMI-DHDCSXOGSA-N 454307 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2-chloro-5-(methylsulfonyl)-1H-indol-3- yl)-N,N-dimethylbenzenesulfonamide::US10717733, Compound 100::US11098045, Compound 100 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454307 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454307&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340285 440970185 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933495 Cc1c(-c2cc(C)nc(C)c2)c2cc(ccc2n1C\C(F)=C\CN)[N+]([O-])=O InChI=1S/C20H21FN4O2/c1-12-8-15(9-13(2)23-12)20-14(3)24(11-16(21)6-7-22)19-5-4-17(25(26)27)10-18(19)20/h4-6,8-10H,7,11,22H2,1-3H3/b16-6- AIJWVRGDHRJJNV-SOFYXZRVSA-N 454308 (Z)-4-(3-(2,6-dimethylpyridin-4-yl)-2- methyl-5-nitro-1H-indol-1-yl)-3- fluorobut-2-en-1-amine::US10717733, Compound 101::US11098045, Compound 101 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454308 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454308&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340286 440970186 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933497 Cc1c(-c2cc(C)nc(C)c2)c2cc(NS(C)(=O)=O)ccc2n1C\C(F)=C\CN InChI=1S/C21H25FN4O2S/c1-13-9-16(10-14(2)24-13)21-15(3)26(12-17(22)7-8-23)20-6-5-18(11-19(20)21)25-29(4,27)28/h5-7,9-11,25H,8,12,23H2,1-4H3/b17-7- IKBVLJQUKOAAGC-IDUWFGFVSA-N 454309 (Z)-N-(1-(4-amino-2-fluorobut-2-en-1-yl)- 3-(2,6-dimethylpyridin-4-yl)-2-methyl- 1H-indol-5-yl)methanesulfonamide::US10717733, Compound 102::US11098045, Compound 102 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454309 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454309&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302712 440970187 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933499 COCc1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2n1 InChI=1S/C22H27FN4O3S/c1-15-21(16-6-5-7-19(12-16)31(28,29)26(2)3)22-20(9-8-18(25-22)14-30-4)27(15)13-17(23)10-11-24/h5-10,12H,11,13-14,24H2,1-4H3/b17-10- RYVSADMCIOYOQZ-YVLHZVERSA-N 454310 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-(methoxymethyl)-2-methyl-1H- pyrrolo[3,2-b]pyridin-3-yl)-N,N- dimethylbenzenesulfonamide::US10717733, Compound 103::US11098045, Compound 103 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454310 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454310&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130341128 440970188 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933501 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(NS(C)(=O)=O)cc12 InChI=1S/C22H27FN4O4S2/c1-15-22(16-6-5-7-19(12-16)33(30,31)26(2)3)20-13-18(25-32(4,28)29)8-9-21(20)27(15)14-17(23)10-11-24/h5-10,12-13,25H,11,14,24H2,1-4H3/b17-10- FHUDTBDZOLHKBL-YVLHZVERSA-N 454311 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2-methyl-5-(methylsulfonamido)-1H- indol-3-yl)-N,N- dimethylbenzenesulfonamide::US10717733, Compound 104::US11098045, Compound 104 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454311 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454311&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302697 440970189 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933503 CN(C)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2n1 InChI=1S/C22H28FN5O2S/c1-15-21(16-7-6-8-18(13-16)31(29,30)27(4)5)22-19(9-10-20(25-22)26(2)3)28(15)14-17(23)11-12-24/h6-11,13H,12,14,24H2,1-5H3/b17-11- RFHRANNTRQLTOA-BOPFTXTBSA-N 454312 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-(dimethylamino)-2-methyl-1H- pyrrolo[3,2-b]pyridin-3-yl)-N,N- dimethylbenzenesulfonamide::US10717733, Compound 105::US11098045, Compound 105 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454312 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454312&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302578 440970190 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933505 CC(C)S(=O)(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2c1 InChI=1S/C24H30FN3O4S2/c1-16(2)33(29,30)20-9-10-23-22(14-20)24(17(3)28(23)15-19(25)11-12-26)18-7-6-8-21(13-18)34(31,32)27(4)5/h6-11,13-14,16H,12,15,26H2,1-5H3/b19-11- YMDVIXFCDYEIOK-ODLFYWEKSA-N 454313 (Z)-3-(1-(4-amino-2-fluorobut-2-en-l-yl)- 5-(isopropylsulfonyl)-2-methyl-1H-indol- 3-yl)-N,N-dimethylbenzenesulfonamide::US10717733, Compound 106::US11098045, Compound 106 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454313 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454313&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302726 440970191 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933507 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(C)nc12 InChI=1S/C21H25FN4O2S/c1-14-8-9-19-21(24-14)20(15(2)26(19)13-17(22)10-11-23)16-6-5-7-18(12-16)29(27,28)25(3)4/h5-10,12H,11,13,23H2,1-4H3/b17-10- AQVVXVOWPOXVME-YVLHZVERSA-N 454314 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2,5-dimethyl-1H-pyrrolo[3,2-b]pyridin-3- yl)-N,N-dimethylbenzenesulfonamide::US10717733, Compound 107::US11098045, Compound 107 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454314&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340700 440970192 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933509 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2cc(F)cnc12 InChI=1S/C20H22F2N4O2S/c1-13-19(14-5-4-6-17(9-14)29(27,28)25(2)3)20-18(10-16(22)11-24-20)26(13)12-15(21)7-8-23/h4-7,9-11H,8,12,23H2,1-3H3/b15-7- GTWOFLYRSQOOCV-CHHVJCJISA-N 454315 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 6-fluoro-2-methyl-1H-pyrrolo[3,2- b]pyridin-3-yl)-N,N- dimethylbenzenesulfonamide::US10717733, Compound 108::US11098045, Compound 108 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454315 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454315&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302805 440970193 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933511 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(F)nc12 InChI=1S/C20H22F2N4O2S/c1-13-19(14-5-4-6-16(11-14)29(27,28)25(2)3)20-17(7-8-18(22)24-20)26(13)12-15(21)9-10-23/h4-9,11H,10,12,23H2,1-3H3/b15-9- GTHWWFKHEBCKQA-DHDCSXOGSA-N 454316 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-fluoro-2-methyl-1H-pyrrolo[3,2- b]pyridin-3-yl)-N,N- dimethylbenzenesulfonamide::US10717733, Compound 109::US11098045, Compound 109 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454316 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454316&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302799 440970194 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933513 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(nc12)C(F)(F)F InChI=1S/C21H22F4N4O2S/c1-13-19(14-5-4-6-16(11-14)32(30,31)28(2)3)20-17(29(13)12-15(22)9-10-26)7-8-18(27-20)21(23,24)25/h4-9,11H,10,12,26H2,1-3H3/b15-9- JKEQDBASFYMVAI-DHDCSXOGSA-N 454317 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2-methyl-5-(trifluoromethyl)-1H- pyrrolo[3,2-b]pyridin-3-yl)-N,N- dimethylbenzenesulfonamide::US10717733, Compound 110::US11098045, Compound 110 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454317 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454317&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340701 440970195 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933515 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(nc12)C(C)(F)F InChI=1S/C22H25F3N4O2S/c1-14-20(15-6-5-7-17(12-15)32(30,31)28(3)4)21-18(29(14)13-16(23)10-11-26)8-9-19(27-21)22(2,24)25/h5-10,12H,11,13,26H2,1-4H3/b16-10- NGRUWSPCBZSMMF-YBEGLDIGSA-N 454318 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-(1,1-difluoroethyl)-2-methyl-1H- pyrrolo[3,2-b]pyridin-3-yl)-N,N- dimethylbenzenesulfonamide::US10717733, Compound 111::US11098045, Compound 111 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454318 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454318&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340723 440970196 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933517 Cc1c(-c2cccc(c2)S(C)(=O)=O)c2nc(C)ccc2n1C\C(F)=C\CN InChI=1S/C20H22FN3O2S/c1-13-7-8-18-20(23-13)19(14(2)24(18)12-16(21)9-10-22)15-5-4-6-17(11-15)27(3,25)26/h4-9,11H,10,12,22H2,1-3H3/b16-9- NYZBHVWJAALINP-SXGWCWSVSA-N 454319 (Z)-4-(2,5-dimethyl-3-(3- (methylsulfonyl)phenyl)-1H-pyrrolo[3,2- b]pyridin-1-yl)-3-fluorobut-2-en-1-amine::US10717733, Compound 112::US11098045, Compound 112 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454319 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454319&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130338729 440970197 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933519 CCS(=O)(=O)c1cccc(c1)-c1c(C(C)C)n(C\C(F)=C\CN)c2ccc(C)nc12 InChI=1S/C23H28FN3O2S/c1-5-30(28,29)19-8-6-7-17(13-19)21-22-20(10-9-16(4)26-22)27(23(21)15(2)3)14-18(24)11-12-25/h6-11,13,15H,5,12,14,25H2,1-4H3/b18-11- JMDGXURWTPBBKZ-WQRHYEAKSA-N 454320 (Z)-4-(3-(3-(ethylsulfonyl)phenyl)-2- isopropyl-5-methyl-1H-pyrrolo[3,2- b]pyridin-1-yl)-3-fluorobut-2-en-1-amine::US10717733, Compound 113::US11098045, Compound 113 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454320&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340722 440970198 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933521 CCS(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(C)nc12 InChI=1S/C21H24FN3O2S/c1-4-28(26,27)18-7-5-6-16(12-18)20-15(3)25(13-17(22)10-11-23)19-9-8-14(2)24-21(19)20/h5-10,12H,4,11,13,23H2,1-3H3/b17-10- AYZZKAOGENBSFB-YVLHZVERSA-N 454321 (Z)-4-(3-(3-(ethylsulfonyl)phenyl)-2,5- dimethyl-1H-pyrrolo[3,2-b]pyridin-1-yl)- 3-fluorobut-2-en-1-amine::US10717733, Compound 114::US11098045, Compound 114 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454321 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454321&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302734 440970199 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933523 Cc1c(-c2cccc(c2)S(C)(=O)=O)c2nc(CF)ccc2n1C\C(F)=C\CN InChI=1S/C20H21F2N3O2S/c1-13-19(14-4-3-5-17(10-14)28(2,26)27)20-18(7-6-16(11-21)24-20)25(13)12-15(22)8-9-23/h3-8,10H,9,11-12,23H2,1-2H3/b15-8- JPBMGMVQTZIBNS-NVNXTCNLSA-N 454322 (Z)-3-fluoro-4-(5-(fluoromethyl)-2- methyl-3-(3-(methylsulfonyl)phenyl)-1H- pyrrolo[3,2-b]pyridin-1-yl)but-2-en-1- amine::US10717733, Compound 115::US11098045, Compound 115 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454322 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454322&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302771 440970200 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933525 Cc1c(-c2cccc(c2)S(C)(=O)=O)c2nc(ccc2n1C\C(F)=C\CN)C(C)(C)O InChI=1S/C22H26FN3O3S/c1-14-20(15-6-5-7-17(12-15)30(4,28)29)21-18(26(14)13-16(23)10-11-24)8-9-19(25-21)22(2,3)27/h5-10,12,27H,11,13,24H2,1-4H3/b16-10- GTDQVLPLHMHYBU-YBEGLDIGSA-N 454323 (Z)-2-(1-(4-amino-2-fluorobut-2-en-1-yl- 2-methyl-3-(3-(methylsulfonyl)phenyl)- 1H-pyrrolo[3,2-b]pyridin-5-yl)propan-2-ol::US10717733, Compound 116::US11098045, Compound 116 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454323 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454323&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340699 440970201 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933527 CC(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(nc12)C(C)(C)O InChI=1S/C24H30FN3O3S/c1-15(2)32(30,31)19-8-6-7-17(13-19)22-16(3)28(14-18(25)11-12-26)20-9-10-21(24(4,5)29)27-23(20)22/h6-11,13,15,29H,12,14,26H2,1-5H3/b18-11- RKQWCPPUHXDGML-WQRHYEAKSA-N 454324 (Z)-2-(1-(4-amino-2-fluorobut-2-en-1-yl)- 3-(3-(isopropylsulfonyl)phenyl)-2-methyl- 1H-pyrrolo[3,2-b]pyridin-5-yl)propan-2-ol::US10717733, Compound 117::US11098045, Compound 117 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q29K4F8R aid1804629 US10717733 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454324&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302754 440970202 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933755 NCCC#N InChI=1S/C3H6N2/c4-2-1-3-5/h1-2,4H2 AGSPXMVUFBBBMO-UHFFFAOYSA-N 50232678 CHEBI:27413::CHEMBL1618272::US10717734, Compound BAPN::US11098045, Compound BAPN Oxidized low-density lipoprotein receptor 1 >1000000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50232678 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50232678&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 1647 384583164 CHEMBL1618272 C05670 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933757 CN(C)S(=O)(=O)c1ccc(Cc2c(C)n(C\C(F)=C\CN)c3ccc(cc23)C(O)=O)cc1 InChI=1S/C23H26FN3O4S/c1-15-20(12-16-4-7-19(8-5-16)32(30,31)26(2)3)21-13-17(23(28)29)6-9-22(21)27(15)14-18(24)10-11-25/h4-10,13H,11-12,14,25H2,1-3H3,(H,28,29)/b18-10- UFVLHUTZCSGQSG-ZDLGFXPLSA-N 454325 US10717734, Compound 1 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454325&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130335759 440970203 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933759 COC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(Cc3ccc(cc3)S(=O)(=O)N(C)C)c2c1 InChI=1S/C24H28FN3O4S/c1-16-21(13-17-5-8-20(9-6-17)33(30,31)27(2)3)22-14-18(24(29)32-4)7-10-23(22)28(16)15-19(25)11-12-26/h5-11,14H,12-13,15,26H2,1-4H3/b19-11- MPHGPIVRFONGMX-ODLFYWEKSA-N 454326 US10717734, Compound 2 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454326 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454326&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130335893 440970204 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933761 CN(C)C(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(Cc3ccc(cc3)S(=O)(=O)N(C)C)c2c1 InChI=1S/C25H31FN4O3S/c1-17-22(14-18-6-9-21(10-7-18)34(32,33)29(4)5)23-15-19(25(31)28(2)3)8-11-24(23)30(17)16-20(26)12-13-27/h6-12,15H,13-14,16,27H2,1-5H3/b20-12- SQBSNZNAVXCFGJ-NDENLUEZSA-N 454327 US10717734, Compound 3 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454327 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454327&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130335653 440970205 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933763 CN(C)S(=O)(=O)c1ccc(Cc2c(C)n(C\C(F)=C\CN)c3ccc(cc23)C(N)=O)cc1 InChI=1S/C23H27FN4O3S/c1-15-20(12-16-4-7-19(8-5-16)32(30,31)27(2)3)21-13-17(23(26)29)6-9-22(21)28(15)14-18(24)10-11-25/h4-10,13H,11-12,14,25H2,1-3H3,(H2,26,29)/b18-10- SJEJOZWJWTZACG-ZDLGFXPLSA-N 454328 US10717734, Compound 4 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454328 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454328&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130335649 440970206 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933765 CN(C)C(=O)c1c(Cc2ccc(cc2)S(=O)(=O)N(C)C)c2ccccc2n1C\C(F)=C\CN InChI=1S/C24H29FN4O3S/c1-27(2)24(30)23-21(15-17-9-11-19(12-10-17)33(31,32)28(3)4)20-7-5-6-8-22(20)29(23)16-18(25)13-14-26/h5-13H,14-16,26H2,1-4H3/b18-13- BGDMXNVSBAZIDX-AQTBWJFISA-N 454329 US10717734, Compound 5 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454329 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454329&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130335655 440970207 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933767 CN(C)S(=O)(=O)c1ccc(Cc2c(C)n(C\C(F)=C\CN)c3ccc(cc23)S(=O)(=O)N(C)C)cc1 InChI=1S/C24H31FN4O4S2/c1-17-22(14-18-6-8-20(9-7-18)34(30,31)27(2)3)23-15-21(35(32,33)28(4)5)10-11-24(23)29(17)16-19(25)12-13-26/h6-12,15H,13-14,16,26H2,1-5H3/b19-12- MYJLNDZKDKIMLC-UNOMPAQXSA-N 454330 US10717734, Compound 6 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454330&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130335648 440970208 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933769 CN(C)S(=O)(=O)c1cccc(Cc2c(C)n(C\C(F)=C\CN)c3ccc(cc23)S(=O)(=O)N(C)C)c1 InChI=1S/C24H31FN4O4S2/c1-17-22(14-18-7-6-8-20(13-18)34(30,31)27(2)3)23-15-21(35(32,33)28(4)5)9-10-24(23)29(17)16-19(25)11-12-26/h6-11,13,15H,12,14,16,26H2,1-5H3/b19-11- GREZYWHAPQLZSP-ODLFYWEKSA-N 454331 US10717734, Compound 7 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454331 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454331&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130335927 440970209 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933771 CN(C)S(=O)(=O)c1ccc(Cc2c(C)n(C\C(F)=C\CN)c3cccnc23)cc1 InChI=1S/C21H25FN4O2S/c1-15-19(13-16-6-8-18(9-7-16)29(27,28)25(2)3)21-20(5-4-12-24-21)26(15)14-17(22)10-11-23/h4-10,12H,11,13-14,23H2,1-3H3/b17-10- NZYJHODIVBUAHN-YVLHZVERSA-N 454332 US10717734, Compound 8 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454332 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454332&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130335929 440970210 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933773 CN(C)S(=O)(=O)c1ccc(Cc2c(C)n(C\C(F)=C\CN)c3ccc(C)nc23)cc1 InChI=1S/C22H27FN4O2S/c1-15-5-10-21-22(25-15)20(16(2)27(21)14-18(23)11-12-24)13-17-6-8-19(9-7-17)30(28,29)26(3)4/h5-11H,12-14,24H2,1-4H3/b18-11- DRNXFUVCBCNQHP-WQRHYEAKSA-N 454333 US10717734, Compound 9 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454333 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454333&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130335666 440970211 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933775 Cc1c(Cc2ccc(cc2)S(C)(=O)=O)c2ncccc2n1C\C(F)=C\CN InChI=1S/C20H22FN3O2S/c1-14-18(12-15-5-7-17(8-6-15)27(2,25)26)20-19(4-3-11-23-20)24(14)13-16(21)9-10-22/h3-9,11H,10,12-13,22H2,1-2H3/b16-9- NMSRUUWTHLKRDU-SXGWCWSVSA-N 454334 US10717734, Compound 10 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454334 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454334&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130335928 440970212 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933777 CN(C)S(=O)(=O)c1ccc(Cc2c(C)n(C\C(F)=C\CN)c3cc(C)cnc23)cc1 InChI=1S/C22H27FN4O2S/c1-15-11-21-22(25-13-15)20(16(2)27(21)14-18(23)9-10-24)12-17-5-7-19(8-6-17)30(28,29)26(3)4/h5-9,11,13H,10,12,14,24H2,1-4H3/b18-9- WNJDRVPTWPAQOE-NVMNQCDNSA-N 454335 US10717734, Compound 11 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454335 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454335&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130335756 440970213 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933779 Cc1c(Cc2ccc(cc2)S(C)(=O)=O)c2nc(C)ccc2n1C\C(F)=C\CN InChI=1S/C21H24FN3O2S/c1-14-4-9-20-21(24-14)19(15(2)25(20)13-17(22)10-11-23)12-16-5-7-18(8-6-16)28(3,26)27/h4-10H,11-13,23H2,1-3H3/b17-10- RNSIYLQIYZOPAG-YVLHZVERSA-N 454336 US10717734, Compound 12 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454336 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454336&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130335650 440970214 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933781 Cc1c(Cc2ccc(nc2)S(C)(=O)=O)c2nc(C)ccc2n1C\C(F)=C\CN InChI=1S/C20H23FN4O2S/c1-13-4-6-18-20(24-13)17(14(2)25(18)12-16(21)8-9-22)10-15-5-7-19(23-11-15)28(3,26)27/h4-8,11H,9-10,12,22H2,1-3H3/b16-8- XYIBLZFCWWUHBV-PXNMLYILSA-N 454337 US10717734, Compound 13 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454337 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454337&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130335652 440970215 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933783 Cc1c(Cc2ccc(cn2)S(C)(=O)=O)c2nc(C)ccc2n1C\C(F)=C\CN InChI=1S/C20H23FN4O2S/c1-13-4-7-19-20(24-13)18(14(2)25(19)12-15(21)8-9-22)10-16-5-6-17(11-23-16)28(3,26)27/h4-8,11H,9-10,12,22H2,1-3H3/b15-8- PDLZPUKGZZHLND-NVNXTCNLSA-N 454338 US10717734, Compound 14 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454338&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130303343 440970216 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933785 CN(C)S(=O)(=O)c1ccc(Cc2c(C)n(C\C(F)=C\CN)c3ccc(C)nc23)nc1 InChI=1S/C21H26FN5O2S/c1-14-5-8-20-21(25-14)19(15(2)27(20)13-16(22)9-10-23)11-17-6-7-18(12-24-17)30(28,29)26(3)4/h5-9,12H,10-11,13,23H2,1-4H3/b16-9- GHWXXHYOOFDZKN-SXGWCWSVSA-N 454339 US10717734, Compound 15 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454339 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454339&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130335651 440970217 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933787 CN(C)S(=O)(=O)c1ccc(Cc2c(C)n(C\C(F)=C\CN)c3ccc(C)nc23)cn1 InChI=1S/C21H26FN5O2S/c1-14-5-7-19-21(25-14)18(15(2)27(19)13-17(22)9-10-23)11-16-6-8-20(24-12-16)30(28,29)26(3)4/h5-9,12H,10-11,13,23H2,1-4H3/b17-9- PSGOGNKVMSGUBO-MFOYZWKCSA-N 454340 US10717734, Compound 16 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454340 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454340&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130335654 440970218 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933789 Cc1c(Cc2cccc(c2)S(C)(=O)=O)c2nc(C)ccc2n1C\C(F)=C\CN InChI=1S/C21H24FN3O2S/c1-14-7-8-20-21(24-14)19(15(2)25(20)13-17(22)9-10-23)12-16-5-4-6-18(11-16)28(3,26)27/h4-9,11H,10,12-13,23H2,1-3H3/b17-9- LXVXWUDYPIPAKE-MFOYZWKCSA-N 454341 US10717734, Compound 17 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454341&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130335932 440970219 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933791 CN(C)S(=O)(=O)c1cccc(Cc2c(C)n(C\C(F)=C\CN)c3ccc(C)nc23)c1 InChI=1S/C22H27FN4O2S/c1-15-8-9-21-22(25-15)20(16(2)27(21)14-18(23)10-11-24)13-17-6-5-7-19(12-17)30(28,29)26(3)4/h5-10,12H,11,13-14,24H2,1-4H3/b18-10- FVVWNLUUKIPVLO-ZDLGFXPLSA-N 454342 US10717734, Compound 18 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454342 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454342&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 138558641 440970220 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933793 CN(C)S(=O)(=O)c1ccc(Cc2c(C)n(C\C(F)=C\CN)c3cc(C)c(O)nc23)cc1 InChI=1S/C22H27FN4O3S/c1-14-11-20-21(25-22(14)28)19(15(2)27(20)13-17(23)9-10-24)12-16-5-7-18(8-6-16)31(29,30)26(3)4/h5-9,11H,10,12-13,24H2,1-4H3,(H,25,28)/b17-9- HJMPZWDNLQPDAT-MFOYZWKCSA-N 454343 US10717734, Compound 19 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454343 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454343&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130303333 440970221 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933795 Cc1c(Cc2ccc(cc2Cl)S(C)(=O)=O)c2ncccc2n1C\C(F)=C\CN InChI=1S/C20H21ClFN3O2S/c1-13-17(10-14-5-6-16(11-18(14)21)28(2,26)27)20-19(4-3-9-24-20)25(13)12-15(22)7-8-23/h3-7,9,11H,8,10,12,23H2,1-2H3/b15-7- TYKLJVDJCYXMLI-CHHVJCJISA-N 454344 US10717734, Compound 20 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454344&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130335933 440970222 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933797 C\C=C(/F)Cn1c(C)c(Oc2ccc(cc2)S(=O)(=O)N(C)C)c2ccccc12 InChI=1S/C21H23FN2O3S/c1-5-16(22)14-24-15(2)21(19-8-6-7-9-20(19)24)27-17-10-12-18(13-11-17)28(25,26)23(3)4/h5-13H,14H2,1-4H3/b16-5- YTVZFTJTYZMEBV-BNCCVWRVSA-N 454345 US10717734, Compound 21 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454345 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454345&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 155883661 440970223 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933799 CN(C)S(=O)(=O)c1ccc(Cc2c(C)n(C\C(F)=C\CN)c3ccc(F)nc23)cc1 InChI=1S/C21H24F2N4O2S/c1-14-18(12-15-4-6-17(7-5-15)30(28,29)26(2)3)21-19(8-9-20(23)25-21)27(14)13-16(22)10-11-24/h4-10H,11-13,24H2,1-3H3/b16-10- FDPCPAZFWYCATQ-YBEGLDIGSA-N 454346 US10717734, Compound 22::US10717734, Compound 23 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454346&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130336187 440970224 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933801 CN(C)S(=O)(=O)c1ccc(Cc2c(C)n(C\C(F)=C\CN)c3ccc(F)nc23)cc1 InChI=1S/C21H24F2N4O2S/c1-14-18(12-15-4-6-17(7-5-15)30(28,29)26(2)3)21-19(8-9-20(23)25-21)27(14)13-16(22)10-11-24/h4-10H,11-13,24H2,1-3H3/b16-10- FDPCPAZFWYCATQ-YBEGLDIGSA-N 454346 US10717734, Compound 22::US10717734, Compound 23 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454346&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130336187 440970224 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933803 CN(C)S(=O)(=O)c1ccc(Cc2c(C)n(C\C(F)=C\CN)c3cc(F)cnc23)cc1 InChI=1S/C21H24F2N4O2S/c1-14-19(10-15-4-6-18(7-5-15)30(28,29)26(2)3)21-20(11-17(23)12-25-21)27(14)13-16(22)8-9-24/h4-8,11-12H,9-10,13,24H2,1-3H3/b16-8- DWWZTEIUFVLJHZ-PXNMLYILSA-N 454348 US10717734, Compound 24 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454348 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454348&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130335917 440970225 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933805 CC(C)(O)c1c(Cc2ccc(cc2)S(C)(=O)=O)c2ncccc2n1C\C(F)=C\CN InChI=1S/C22H26FN3O3S/c1-22(2,27)21-18(13-15-6-8-17(9-7-15)30(3,28)29)20-19(5-4-12-25-20)26(21)14-16(23)10-11-24/h4-10,12,27H,11,13-14,24H2,1-3H3/b16-10- YNUOGUXJDXXSCR-YBEGLDIGSA-N 454349 US10717734, Compound 25 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454349&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 138558618 440970226 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933807 CN(C)S(=O)(=O)c1ccc(Cc2c(C)n(C\C(F)=C\CN)c3ccccc23)cc1 InChI=1S/C22H26FN3O2S/c1-16-21(14-17-8-10-19(11-9-17)29(27,28)25(2)3)20-6-4-5-7-22(20)26(16)15-18(23)12-13-24/h4-12H,13-15,24H2,1-3H3/b18-12- CBQJSFSCVJDQFY-PDGQHHTCSA-N 454350 US10717734, Compound 26 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454350&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130335661 440970227 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933809 Cc1c(Cc2ccc(nc2)S(C)(=O)=O)c2nc(ccc2n1C\C(F)=C\CN)C1CC1 InChI=1S/C22H25FN4O2S/c1-14-18(11-15-3-8-21(25-12-15)30(2,28)29)22-20(27(14)13-17(23)9-10-24)7-6-19(26-22)16-4-5-16/h3,6-9,12,16H,4-5,10-11,13,24H2,1-2H3/b17-9- NOJNQZDSMWHCKX-MFOYZWKCSA-N 454351 US10717734, Compound 27 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454351&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130335660 440970228 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933811 CN(C)S(=O)(=O)c1ccc(Cc2c(C)n(C\C(F)=C\CN)c3ccc(nc23)C(C)(C)O)cc1 InChI=1S/C24H31FN4O3S/c1-16-20(14-17-6-8-19(9-7-17)33(31,32)28(4)5)23-21(29(16)15-18(25)12-13-26)10-11-22(27-23)24(2,3)30/h6-12,30H,13-15,26H2,1-5H3/b18-12- MDYCUMUJRNXZOV-PDGQHHTCSA-N 454352 US10717734, Compound 28 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454352 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454352&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130335663 440970229 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933813 CC(O)c1c(Cc2ccc(cc2)S(=O)(=O)N(C)C)c2ncccc2n1C\C(F)=C\CN InChI=1S/C22H27FN4O3S/c1-15(28)22-19(13-16-6-8-18(9-7-16)31(29,30)26(2)3)21-20(5-4-12-25-21)27(22)14-17(23)10-11-24/h4-10,12,15,28H,11,13-14,24H2,1-3H3/b17-10- QZJVGNWPJBOTRW-YVLHZVERSA-N 454353 US10717734, Compound 29 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454353&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130303339 440970230 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933815 Cc1c(Cc2ccc(nc2)S(C)(=O)=O)c2nc(ccc2n1C\C(F)=C\CN)C(C)(F)F InChI=1S/C21H23F3N4O2S/c1-13-16(10-14-4-7-19(26-11-14)31(3,29)30)20-17(28(13)12-15(22)8-9-25)5-6-18(27-20)21(2,23)24/h4-8,11H,9-10,12,25H2,1-3H3/b15-8- NKZJFBGESYRVGV-NVNXTCNLSA-N 454354 US10717734, Compound 30 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454354 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454354&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130335662 440970231 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933817 Cc1c(Cc2ccc(nc2)S(C)(=O)=O)c2nc(ccc2n1C\C(F)=C\CN)C(F)(F)F InChI=1S/C20H20F4N4O2S/c1-12-15(9-13-3-6-18(26-10-13)31(2,29)30)19-16(28(12)11-14(21)7-8-25)4-5-17(27-19)20(22,23)24/h3-7,10H,8-9,11,25H2,1-2H3/b14-7- CDUNOPMZBFLOLR-AUWJEWJLSA-N 454355 US10717734, Compound 31 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454355 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454355&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130336179 440970232 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933819 CN(C)S(=O)(=O)c1ccc(Cc2c(C)n(C\C(F)=C\CN)c3ccncc23)cc1 InChI=1S/C21H25FN4O2S/c1-15-19(12-16-4-6-18(7-5-16)29(27,28)25(2)3)20-13-24-11-9-21(20)26(15)14-17(22)8-10-23/h4-9,11,13H,10,12,14,23H2,1-3H3/b17-8- ZLTOLOZKNKVNCB-IUXPMGMMSA-N 454356 US10717734, Compound 32 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454356&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130335936 440970233 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933821 CC(C)c1c(Cc2ccc(cc2)S(C)(=O)=O)c2ncccc2n1C\C(F)=C\CN InChI=1S/C22H26FN3O2S/c1-15(2)22-19(13-16-6-8-18(9-7-16)29(3,27)28)21-20(5-4-12-25-21)26(22)14-17(23)10-11-24/h4-10,12,15H,11,13-14,24H2,1-3H3/b17-10- RPVREYBVSIJBAA-YVLHZVERSA-N 454357 US10717734, Compound 33 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454357 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454357&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130303301 440970234 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933823 Cc1c(Cc2ccc(cc2C)S(C)(=O)=O)c2ncccc2n1C\C(F)=C\CN InChI=1S/C21H24FN3O2S/c1-14-11-18(28(3,26)27)7-6-16(14)12-19-15(2)25(13-17(22)8-9-23)20-5-4-10-24-21(19)20/h4-8,10-11H,9,12-13,23H2,1-3H3/b17-8- SPWGPEBXVUBGMH-IUXPMGMMSA-N 454358 US10717734, Compound 34 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454358 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454358&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130303344 440970235 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933825 Cc1c(Cc2ccc(c(Cl)c2)S(C)(=O)=O)c2ncccc2n1C\C(F)=C\CN InChI=1S/C20H21ClFN3O2S/c1-13-16(10-14-5-6-19(17(21)11-14)28(2,26)27)20-18(4-3-9-24-20)25(13)12-15(22)7-8-23/h3-7,9,11H,8,10,12,23H2,1-2H3/b15-7- BVAOUQAQMVOOJV-CHHVJCJISA-N 454359 US10717734, Compound 35 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454359 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454359&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130336008 440970236 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933827 Cc1c(Cc2ccc(cc2)S(C)(=O)=O)c2cnc(C)cc2n1C\C(F)=C\CN InChI=1S/C21H24FN3O2S/c1-14-10-21-20(12-24-14)19(15(2)25(21)13-17(22)8-9-23)11-16-4-6-18(7-5-16)28(3,26)27/h4-8,10,12H,9,11,13,23H2,1-3H3/b17-8- BOOIHBMQEKFNSJ-IUXPMGMMSA-N 454360 US10717734, Compound 36 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454360&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130303293 440970237 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933829 CN(C)S(=O)(=O)c1ccc(Cc2c(C)n(C\C(F)=C\CN)c3cc(C)nnc23)cc1 InChI=1S/C21H26FN5O2S/c1-14-11-20-21(25-24-14)19(15(2)27(20)13-17(22)9-10-23)12-16-5-7-18(8-6-16)30(28,29)26(3)4/h5-9,11H,10,12-13,23H2,1-4H3/b17-9- MXPFPFGRIOXRSC-MFOYZWKCSA-N 454361 US10717734, Compound 37 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454361 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454361&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130336002 440970238 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933831 Cc1c(Cc2ccc(cc2)S(C)(=O)=O)c2nc(C)ncc2n1C\C(F)=C\CN InChI=1S/C20H23FN4O2S/c1-13-18(10-15-4-6-17(7-5-15)28(3,26)27)20-19(11-23-14(2)24-20)25(13)12-16(21)8-9-22/h4-8,11H,9-10,12,22H2,1-3H3/b16-8- MZVIVWJFOKCJPB-PXNMLYILSA-N 454362 US10717734, Compound 38 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454362 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454362&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130335718 440970239 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933833 CN(C)S(=O)(=O)c1ccc(Cc2c(C)n(C\C(F)=C\CN)c3cnc(C)nc23)cc1 InChI=1S/C21H26FN5O2S/c1-14-19(11-16-5-7-18(8-6-16)30(28,29)26(3)4)21-20(12-24-15(2)25-21)27(14)13-17(22)9-10-23/h5-9,12H,10-11,13,23H2,1-4H3/b17-9- MAFORJXJXGOEGW-MFOYZWKCSA-N 454363 US10717734, Compound 39 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454363 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454363&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130335705 440970240 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933835 Cc1c(CCc2ccc(cc2)S(C)(=O)=O)c2nc(C)ccc2n1C\C(F)=C\CN InChI=1S/C22H26FN3O2S/c1-15-4-11-21-22(25-15)20(16(2)26(21)14-18(23)12-13-24)10-7-17-5-8-19(9-6-17)29(3,27)28/h4-6,8-9,11-12H,7,10,13-14,24H2,1-3H3/b18-12- VEMXPBOWLXFFSF-PDGQHHTCSA-N 454364 US10717734, Compound 40 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454364 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454364&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130335710 440970241 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933837 CC(C)c1c(Cc2ccc(nc2)S(=O)(=O)C(C)C)c2ncccc2n1C\C(F)=C\CN InChI=1S/C23H29FN4O2S/c1-15(2)23-19(12-17-7-8-21(27-13-17)31(29,30)16(3)4)22-20(6-5-11-26-22)28(23)14-18(24)9-10-25/h5-9,11,13,15-16H,10,12,14,25H2,1-4H3/b18-9- GIOPVJWOYZBTNW-NVMNQCDNSA-N 454365 US10717734, Compound 41 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454365 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454365&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130335719 440970242 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933839 CC(C)c1c(C(O)c2ccc(nc2)S(C)(=O)=O)c2ncccc2n1C\C(F)=C\CN InChI=1S/C21H25FN4O3S/c1-13(2)20-18(21(27)14-6-7-17(25-11-14)30(3,28)29)19-16(5-4-10-24-19)26(20)12-15(22)8-9-23/h4-8,10-11,13,21,27H,9,12,23H2,1-3H3/b15-8- IGAHCCXZSLYWHZ-NVNXTCNLSA-N 454366 US10717734, Compound 42 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454366 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454366&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130335720 440970243 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933841 CCS(=O)(=O)c1ccc(Cc2c(C(C)C)n(C\C(F)=C\CN)c3cccnc23)cn1 InChI=1S/C22H27FN4O2S/c1-4-30(28,29)20-8-7-16(13-26-20)12-18-21-19(6-5-11-25-21)27(22(18)15(2)3)14-17(23)9-10-24/h5-9,11,13,15H,4,10,12,14,24H2,1-3H3/b17-9- NPLBQMHXRGINNC-MFOYZWKCSA-N 454367 US10717734, Compound 43 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454367 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454367&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130303322 440970244 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 933843 CC(C)c1c(Cc2ccc(nc2)S(=O)(=O)C2CC2)c2ncccc2n1C\C(F)=C\CN InChI=1S/C23H27FN4O2S/c1-15(2)23-19(12-16-5-8-21(27-13-16)31(29,30)18-6-7-18)22-20(4-3-11-26-22)28(23)14-17(24)9-10-25/h3-5,8-9,11,13,15,18H,6-7,10,12,14,25H2,1-2H3/b17-9- GVILXUAFGOZZHX-MFOYZWKCSA-N 454368 US10717734, Compound 44 Oxidized low-density lipoprotein receptor 1 >300000 US Patent 10.7270/Q25T3PHK aid1804632 US10717734 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454368 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454368&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130335715 440970245 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1080999 NCCC#N InChI=1S/C3H6N2/c4-2-1-3-5/h1-2,4H2 AGSPXMVUFBBBMO-UHFFFAOYSA-N 50232678 CHEBI:27413::CHEMBL1618272::US10717734, Compound BAPN::US11098045, Compound BAPN Oxidized low-density lipoprotein receptor 1 >1000 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50232678 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50232678&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 1647 384583164 CHEMBL1618272 C05670 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081001 NC\C=C(/F)Cn1cc(-c2ccc(F)cc2)c2ccccc12 InChI=1S/C18H16F2N2/c19-14-7-5-13(6-8-14)17-12-22(11-15(20)9-10-21)18-4-2-1-3-16(17)18/h1-9,12H,10-11,21H2/b15-9- JPFSOENZKKNKEN-DHDCSXOGSA-N 454208 (Z)-3-fluoro-4-(3-(4-fluorophenyl)-1H- indol-1-yl)but-2-en-1-amine::US10717733, Compound 1::US11098045, Compound 1 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454208 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454208&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340972 440970088 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081003 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccccc12 InChI=1S/C21H24FN3O2S/c1-15-21(16-7-6-8-18(13-16)28(26,27)24(2)3)19-9-4-5-10-20(19)25(15)14-17(22)11-12-23/h4-11,13H,12,14,23H2,1-3H3/b17-11- FFWWSSGIANHKJO-BOPFTXTBSA-N 454209 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2-methyl-1H-indol-3-yl)-N,N- dimethylbenzenesulfonamide::US10717733, Compound 2::US11098045, Compound 2 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454209 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454209&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340971 440970089 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081005 CN(C)S(=O)(=O)c1ccc(cc1)-c1c(C)n(C\C(F)=C\CN)c2ccccc12 InChI=1S/C21H24FN3O2S/c1-15-21(16-8-10-18(11-9-16)28(26,27)24(2)3)19-6-4-5-7-20(19)25(15)14-17(22)12-13-23/h4-12H,13-14,23H2,1-3H3/b17-12- SVIHWIJPHXHIBN-ATVHPVEESA-N 454210 (Z)-4-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2-methyl-1H-indol-3-yl)-N,N- dimethylbenzenesulfonamide::US10717733, Compound 3::US11098045, Compound 3 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454210 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454210&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302638 440970090 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081007 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ncccc12 InChI=1S/C20H23FN4O2S/c1-14-19(15-6-4-7-17(12-15)28(26,27)24(2)3)18-8-5-11-23-20(18)25(14)13-16(21)9-10-22/h4-9,11-12H,10,13,22H2,1-3H3/b16-9- CFXHPCRZYKWUPK-SXGWCWSVSA-N 454211 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)- N,N-dimethylbenzenesulfonamide::US10717733, Compound 4::US11098045, Compound 4 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454211 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454211&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302811 440970091 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081009 COC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2c1 InChI=1S/C23H26FN3O4S/c1-15-22(16-6-5-7-19(12-16)32(29,30)26(2)3)20-13-17(23(28)31-4)8-9-21(20)27(15)14-18(24)10-11-25/h5-10,12-13H,11,14,25H2,1-4H3/b18-10- NRSYNKVPOCKDIH-ZDLGFXPLSA-N 454212 (Z)-methyl 1-(4-amino-2-fluorobut-2-en- 1-yl)-3-(3-N,N- dimethylsulfamoyl)phenyl)-2-methyl-1H- indole-5-carboxylate::US10717733, Compound 5::US11098045, Compound 5 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454212&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340289 440970092 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081011 CN(C)C(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2c1 InChI=1S/C24H29FN4O3S/c1-16-23(17-7-6-8-20(13-17)33(31,32)28(4)5)21-14-18(24(30)27(2)3)9-10-22(21)29(16)15-19(25)11-12-26/h6-11,13-14H,12,15,26H2,1-5H3/b19-11- NJTKSIQWDDYXEM-ODLFYWEKSA-N 454213 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)- N,N,2-trimethyl-1H-indole-5-carboxamide::US10717733, Compound 52::US10717733, Compound 6::US11098045, Compound 52 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454213&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302612 440970093 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081013 COC(=O)c1ccc2c(c(C)n(C\C(F)=C\CN)c2c1)-c1cccc(c1)S(=O)(=O)N(C)C InChI=1S/C23H26FN3O4S/c1-15-22(16-6-5-7-19(12-16)32(29,30)26(2)3)20-9-8-17(23(28)31-4)13-21(20)27(15)14-18(24)10-11-25/h5-10,12-13H,11,14,25H2,1-4H3/b18-10- CTWQNEGONIXSFR-ZDLGFXPLSA-N 454214 (Z)-methyl 1-(4-amino-2-fluorobut-2-en- 1-yl)-3-(3-(N,N- dimethylsulfamoyl)phenyl)-2-methyl-1H- indole-6-carboxylate::US10717733, Compound 7::US11098045, Compound 7 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454214 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454214&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340290 440970094 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081015 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O InChI=1S/C22H24FN3O4S/c1-14-21(15-5-4-6-18(11-15)31(29,30)25(2)3)19-12-16(22(27)28)7-8-20(19)26(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H,27,28)/b17-9- IAOICZAENMLTOU-MFOYZWKCSA-N 454215 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)-2- methyl-1H-indole-5-carboxylic acid::US10717733, Compound 8::US11098045, Compound 8 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454215 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454215&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302629 440970095 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081017 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2cc(ccc12)C(O)=O InChI=1S/C22H24FN3O4S/c1-14-21(15-5-4-6-18(11-15)31(29,30)25(2)3)19-8-7-16(22(27)28)12-20(19)26(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H,27,28)/b17-9- JKFARAGHJZMDQI-MFOYZWKCSA-N 454216 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)-2- methyl-1H-indole-6-carboxylic acid::US10717733, Compound 9::US11098045, Compound 9 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454216 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454216&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340717 440970096 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081019 CN(C)C(=O)c1ccc2c(c(C)n(C\C(F)=C\CN)c2c1)-c1cccc(c1)S(=O)(=O)N(C)C InChI=1S/C24H29FN4O3S/c1-16-23(17-7-6-8-20(13-17)33(31,32)28(4)5)21-10-9-18(24(30)27(2)3)14-22(21)29(16)15-19(25)11-12-26/h6-11,13-14H,12,15,26H2,1-5H3/b19-11- GJILSAQRIPFPDI-ODLFYWEKSA-N 454217 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)- N,N,2-trimethyl-1H-indole-6-carboxamide::US10717733, Compound 10::US11098045, Compound 10 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454217 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454217&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340719 440970097 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081021 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2cc(ccc12)C(N)=O InChI=1S/C22H25FN4O3S/c1-14-21(15-5-4-6-18(11-15)31(29,30)26(2)3)19-8-7-16(22(25)28)12-20(19)27(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H2,25,28)/b17-9- QUUGFFMFKSQZFN-MFOYZWKCSA-N 454218 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)-2- methyl-1H-indole-6-carboxamide::US10717733, Compound 11::US11098045, Compound 11 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454218 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454218&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340720 440970098 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081023 CCOC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2c1 InChI=1S/C24H28FN3O4S/c1-5-32-24(29)18-9-10-22-21(14-18)23(16(2)28(22)15-19(25)11-12-26)17-7-6-8-20(13-17)33(30,31)27(3)4/h6-11,13-14H,5,12,15,26H2,1-4H3/b19-11- HTLNQVKMQMVOPI-ODLFYWEKSA-N 454219 (Z)-ethyl 1-(4-amino-2-fluorobut-2-en-1- yl)-3-(3-(N,N-dimethylsulfamoyl)phenyl)- 2-methyl-1H-indole-5-carboxylate::US10717733, Compound 12::US11098045, Compound 12 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454219 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454219&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340718 440970099 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081025 CN(C)S(=O)(=O)c1cccc(-c2c(C)n(C\C(F)=C\CN)c3ccc(cc23)C(O)=O)c1C InChI=1S/C23H26FN3O4S/c1-14-18(6-5-7-21(14)32(30,31)26(3)4)22-15(2)27(13-17(24)10-11-25)20-9-8-16(23(28)29)12-19(20)22/h5-10,12H,11,13,25H2,1-4H3,(H,28,29)/b17-10- CZPQNEQWQQHYLE-YVLHZVERSA-N 454220 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)-2- methylphenyl)-2-methyl-1H-indole-5- carboxylic acid::US10717733, Compound 13::US11098045, Compound 13 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454220 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454220&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302746 440970100 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081027 Cc1c(-c2cccc(c2)S(C)(=O)=O)c2cc(ccc2n1C\C(F)=C\CN)C(O)=O InChI=1S/C21H21FN2O4S/c1-13-20(14-4-3-5-17(10-14)29(2,27)28)18-11-15(21(25)26)6-7-19(18)24(13)12-16(22)8-9-23/h3-8,10-11H,9,12,23H2,1-2H3,(H,25,26)/b16-8- XAABKVNXUAWXSU-PXNMLYILSA-N 454221 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-2- methyl-3-(3-(methylsulfonyl)phenyl)-1H- indole-5-carboxylic acid::US10717733, Compound 14::US11098045, Compound 14 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454221 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454221&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340281 440970101 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081029 CCOC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)C(=O)N(C)C)c2c1 InChI=1S/C25H28FN3O3/c1-5-32-25(31)19-9-10-22-21(14-19)23(16(2)29(22)15-20(26)11-12-27)17-7-6-8-18(13-17)24(30)28(3)4/h6-11,13-14H,5,12,15,27H2,1-4H3/b20-11- CKGAHBWUJAZHHP-JAIQZWGSSA-N 454222 (Z)-ethyl 1-(4-amino-2-fluorobut-2-en-1- yl)-3-(3-(dimethylcarbamoyl)phenyl)-2- methyl-1H-indole-5-carboxylate::US10717733, Compound 15::US11098045, Compound 15 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454222&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340280 440970102 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081031 CN(C)C(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O InChI=1S/C23H24FN3O3/c1-14-21(15-5-4-6-16(11-15)22(28)26(2)3)19-12-17(23(29)30)7-8-20(19)27(14)13-18(24)9-10-25/h4-9,11-12H,10,13,25H2,1-3H3,(H,29,30)/b18-9- KJKWDAGGVYNCGG-NVMNQCDNSA-N 454223 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(dimethylcarbamoyl)phenyl)-2-methyl- 1H-indole-5-carboxylic acid::US10717733, Compound 16::US11098045, Compound 16 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454223&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340282 440970103 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081033 CCOC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(C)(=O)=O)c2c1 InChI=1S/C23H25FN2O4S/c1-4-30-23(27)17-8-9-21-20(13-17)22(15(2)26(21)14-18(24)10-11-25)16-6-5-7-19(12-16)31(3,28)29/h5-10,12-13H,4,11,14,25H2,1-3H3/b18-10- HLBARMATWYKFAL-ZDLGFXPLSA-N 454224 (Z)-ethyl 1-(4-amino-2-fluorobut-2-en-1- yl)-2-methyl-3-(3- (methylsulfonyl)phenyl)-1H-indole-5- carboxylate::US10717733, Compound 17::US11098045, Compound 17 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454224 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454224&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340921 440970104 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081035 CNS(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O InChI=1S/C21H22FN3O4S/c1-13-20(14-4-3-5-17(10-14)30(28,29)24-2)18-11-15(21(26)27)6-7-19(18)25(13)12-16(22)8-9-23/h3-8,10-11,24H,9,12,23H2,1-2H3,(H,26,27)/b16-8- PCPBDUMNYRZIDJ-PXNMLYILSA-N 454225 (Z)-1-(4-amino-2-fluorobut-2-en-l-yl)-2- methyl-3-(3-(N-methylsulfamoyl)phenyl)- 1H-indole-5-carboxylic acid::US10717733, Compound 18::US11098045, Compound 18 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454225 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454225&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302574 440970105 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081037 CCOC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cc(ccc3C)S(=O)(=O)N(C)C)c2c1 InChI=1S/C25H30FN3O4S/c1-6-33-25(30)18-8-10-23-22(13-18)24(17(3)29(23)15-19(26)11-12-27)21-14-20(9-7-16(21)2)34(31,32)28(4)5/h7-11,13-14H,6,12,15,27H2,1-5H3/b19-11- AYOBNOKYKOMHDO-ODLFYWEKSA-N 454226 (Z)-ethyl 1-(4-amino-2-fluorobut-2-en-1- yl)-3-(5-(N,N-dimethylsulfamoyl)-2- methylphenyl)-2-methyl-1H-indole-5- carboxylate::US10717733, Compound 19::US11098045, Compound 19 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454226 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454226&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340922 440970106 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081039 CN(C)S(=O)(=O)c1ccc(C)c(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O InChI=1S/C23H26FN3O4S/c1-14-5-7-18(32(30,31)26(3)4)12-19(14)22-15(2)27(13-17(24)9-10-25)21-8-6-16(23(28)29)11-20(21)22/h5-9,11-12H,10,13,25H2,1-4H3,(H,28,29)/b17-9- CWGVGNOSBIENPA-MFOYZWKCSA-N 454227 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (5-(N,N-dimethylsulfamoyl)-2- methylphenyl)-2-methyl-1H-indole-5- carboxylic acid::US10717733, Compound 20::US11098045, Compound 20 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454227 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454227&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302751 440970107 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081041 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2cc(F)c(cc12)C(O)=O InChI=1S/C22H23F2N3O4S/c1-13-21(14-5-4-6-16(9-14)32(30,31)26(2)3)18-10-17(22(28)29)19(24)11-20(18)27(13)12-15(23)7-8-25/h4-7,9-11H,8,12,25H2,1-3H3,(H,28,29)/b15-7- FFTPACJQQYAFHN-CHHVJCJISA-N 454228 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)-6- fluoro-2-methyl-1H-indole-5-carboxylic acid::US10717733, Compound 21::US11098045, Compound 21 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454228 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454228&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340437 440970108 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081043 CCOC(=O)c1cc2c(c(C)n(C\C(F)=C\CN)c2cc1F)-c1cccc(c1)S(=O)(=O)N(C)C InChI=1S/C24H27F2N3O4S/c1-5-33-24(30)19-12-20-22(13-21(19)26)29(14-17(25)9-10-27)15(2)23(20)16-7-6-8-18(11-16)34(31,32)28(3)4/h6-9,11-13H,5,10,14,27H2,1-4H3/b17-9- CUXNKRROGVMNPP-MFOYZWKCSA-N 454229 (Z)-ethyl 1-(4-amino-2-fluorobut-2-en-1- yl)-3-(3-(N,N-dimethylsulfamoyl)phenyl)- 6-fluoro-2-methyl-1H-indole-5- carboxylate::US10717733, Compound 22::US11098045, Compound 22 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454229 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454229&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340435 440970109 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081045 Cc1c(-c2ccc(F)cc2)c2cc(ccc2n1C\C(F)=C\CN)C(O)=O InChI=1S/C20H18F2N2O2/c1-12-19(13-2-5-15(21)6-3-13)17-10-14(20(25)26)4-7-18(17)24(12)11-16(22)8-9-23/h2-8,10H,9,11,23H2,1H3,(H,25,26)/b16-8- LVTLXVHXXRMAAZ-PXNMLYILSA-N 454230 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (4-fluorophenyl)-2-methyl-1H-indole-5- carboxylic acid::US10717733, Compound 23::US11098045, Compound 23 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454230 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454230&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302717 440970110 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081047 CCOC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3ccc(F)cc3)c2c1 InChI=1S/C22H22F2N2O2/c1-3-28-22(27)16-6-9-20-19(12-16)21(15-4-7-17(23)8-5-15)14(2)26(20)13-18(24)10-11-25/h4-10,12H,3,11,13,25H2,1-2H3/b18-10- YDGMIZHGNYKRQY-ZDLGFXPLSA-N 454231 US10717733, Compound 24::US11098045, Compound 24::ethyl (Z)-1-(4-amino-2-fluorobut-2-en-1- yl)-3-(4-fluorophenyl)-2-methyl-1H- indole-5-carboxylate Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454231 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454231&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340436 440970111 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081049 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2cccnc12 InChI=1S/C20H23FN4O2S/c1-14-19(15-6-4-7-17(12-15)28(26,27)24(2)3)20-18(8-5-11-23-20)25(14)13-16(21)9-10-22/h4-9,11-12H,10,13,22H2,1-3H3/b16-9- YNYGVGYGPMQAEL-SXGWCWSVSA-N 454232 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2-methyl-1H-pyrrolo[3,2-b]pyridin-3-yl)- N,N-dimethylbenzenesulfonamide::US10717733, Compound 25::US11098045, Compound 25 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454232 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454232&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302687 440970112 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081051 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccncc12 InChI=1S/C20H23FN4O2S/c1-14-20(15-5-4-6-17(11-15)28(26,27)24(2)3)18-12-23-10-8-19(18)25(14)13-16(21)7-9-22/h4-8,10-12H,9,13,22H2,1-3H3/b16-7- NMIOMTWURASXJN-APSNUPSMSA-N 454233 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2-methyl-1H-pyrrolo[3,2-c]pyridin-3-yl- N,N-dimethylbenzenesulfonamide::US10717733, Compound 26::US11098045, Compound 26 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454233 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454233&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340434 440970113 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081053 CCOC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(Cl)c3)c2c1 InChI=1S/C22H22ClFN2O2/c1-3-28-22(27)16-7-8-20-19(12-16)21(15-5-4-6-17(23)11-15)14(2)26(20)13-18(24)9-10-25/h4-9,11-12H,3,10,13,25H2,1-2H3/b18-9- MTEAJOPQXXRPIV-NVMNQCDNSA-N 454234 US10717733, Compound 27::US11098045, Compound 27::ethyl (Z)-1-(4-amino-2-fluorobut-2-en-1- yl)-3-(3-chlorophenyl)-2-methyl-1H- indole-5-carboxylate Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454234 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454234&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340736 440970114 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081055 Cc1c(-c2cccc(Cl)c2)c2cc(ccc2n1C\C(F)=C\CN)C(O)=O InChI=1S/C20H18ClFN2O2/c1-12-19(13-3-2-4-15(21)9-13)17-10-14(20(25)26)5-6-18(17)24(12)11-16(22)7-8-23/h2-7,9-10H,8,11,23H2,1H3,(H,25,26)/b16-7- JPDKCTYHCKAPJF-APSNUPSMSA-N 454235 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-chlorophenyl)-2-methyl-1H-indole-5- carboxylic acid::US10717733, Compound 28::US11098045, Compound 28 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454235 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454235&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302758 440970115 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081057 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)-c1nn[nH]n1 InChI=1S/C22H24FN7O2S/c1-14-21(15-5-4-6-18(11-15)33(31,32)29(2)3)19-12-16(22-25-27-28-26-22)7-8-20(19)30(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H,25,26,27,28)/b17-9- HFXSXVBYINJBIZ-MFOYZWKCSA-N 454236 (Z)-3-(1-(4-amino-2-fluorobut-2-en-l-yl)- 2-methyl-5-(2H-tetrazol-5-yl)-1H-indol-3- yl)-N,N-dimethylbenzenesulfonamide::US10717733, Compound 29::US11098045, Compound 29 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454236 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454236&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302666 440970116 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081059 CCOC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)C(C)(C)C)c2c1 InChI=1S/C26H31FN2O2/c1-6-31-25(30)19-10-11-23-22(15-19)24(17(2)29(23)16-21(27)12-13-28)18-8-7-9-20(14-18)26(3,4)5/h7-12,14-15H,6,13,16,28H2,1-5H3/b21-12- KHWFSMWHXXFYJJ-MTJSOVHGSA-N 454237 US10717733, Compound 30::US11098045, Compound 30::ethyl (Z)-1-(4-amino-2-fluorobut-2-en-1- yl)-3-(3-(tert-butyl)phenyl)-2-methyl-1H- indole-5-carboxylate Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454237 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454237&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340809 440970117 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081061 Cc1c(-c2cccc(c2)C(C)(C)C)c2cc(ccc2n1C\C(F)=C\CN)C(O)=O InChI=1S/C24H27FN2O2/c1-15-22(16-6-5-7-18(12-16)24(2,3)4)20-13-17(23(28)29)8-9-21(20)27(15)14-19(25)10-11-26/h5-10,12-13H,11,14,26H2,1-4H3,(H,28,29)/b19-10- CSAVUFJECWFWKT-GRSHGNNSSA-N 454238 (Z)-1-(4-amino-2-fluorobut-2-en-l-yl)-3- (3-(tert-butyl)phenyl)-2-methyl-1H- indole-5-carboxylic acid::US10717733, Compound 31::US11098045, Compound 31 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454238 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454238&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340810 440970118 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081063 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2cnccc12 InChI=1S/C20H23FN4O2S/c1-14-20(15-5-4-6-17(11-15)28(26,27)24(2)3)18-8-10-23-12-19(18)25(14)13-16(21)7-9-22/h4-8,10-12H,9,13,22H2,1-3H3/b16-7- BKXMWBDHBUXWLZ-APSNUPSMSA-N 454239 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2-methyl-1H-pyrrolo[2,3-c]pyridin-3-yl)- N,N-dimethylbenzenesulfonamide::US10717733, Compound 32::US11098045, Compound 32 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454239 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454239&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302602 440970119 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081065 CCOC(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)S(=O)(=O)N(C)C InChI=1S/C24H28FN3O4S/c1-5-32-24(29)18-8-6-7-17(13-18)23-16(2)28(15-19(25)11-12-26)22-10-9-20(14-21(22)23)33(30,31)27(3)4/h6-11,13-14H,5,12,15,26H2,1-4H3/b19-11- NXNSCGDXGSAYPX-ODLFYWEKSA-N 454240 US10717733, Compound 33::US11098045, Compound 33::ethyl (Z)-3-(1-(4-amino-2-fluorobut-2-en- 1-yl)-5-(N,N-dimethylsulfamoyl)-2- methyl-1H-indol-3-yl)benzoate Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454240 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454240&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340811 440970120 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081067 CN(C)S(=O)(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)C(O)=O)c2c1 InChI=1S/C22H24FN3O4S/c1-14-21(15-5-4-6-16(11-15)22(27)28)19-12-18(31(29,30)25(2)3)7-8-20(19)26(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H,27,28)/b17-9- OAUNHIUUACPTIJ-MFOYZWKCSA-N 454241 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-(N,N-dimethylsulfamoyl)-2-methyl-1H- indol-3-yl)benzoic acid::US10717733, Compound 34::US11098045, Compound 34 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454241 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454241&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302631 440970121 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081069 CC(C)NC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2c1 InChI=1S/C25H31FN4O3S/c1-16(2)28-25(31)19-9-10-23-22(14-19)24(17(3)30(23)15-20(26)11-12-27)18-7-6-8-21(13-18)34(32,33)29(4)5/h6-11,13-14,16H,12,15,27H2,1-5H3,(H,28,31)/b20-11- LUKZWYDVODUKGO-JAIQZWGSSA-N 454242 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)-N- isopropyl-2-methyl-1H-indole-5- carboxamide::US10717733, Compound 35::US11098045, Compound 35 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454242 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454242&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302724 440970122 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081071 CC(C)N(C)C(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2c1 InChI=1S/C26H33FN4O3S/c1-17(2)30(6)26(32)20-10-11-24-23(15-20)25(18(3)31(24)16-21(27)12-13-28)19-8-7-9-22(14-19)35(33,34)29(4)5/h7-12,14-15,17H,13,16,28H2,1-6H3/b21-12- ISPGIAVPCFRBFX-MTJSOVHGSA-N 454243 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)-N- isopropyl-N,2-dimethyl-1H-indole-5- carboxamide::US10717733, Compound 36::US11098045, Compound 36 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454243 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454243&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302642 440970123 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081073 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(O)cc12 InChI=1S/C21H24FN3O3S/c1-14-21(15-5-4-6-18(11-15)29(27,28)24(2)3)19-12-17(26)7-8-20(19)25(14)13-16(22)9-10-23/h4-9,11-12,26H,10,13,23H2,1-3H3/b16-9- VMZRQLIVPKQUDC-SXGWCWSVSA-N 454244 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-hydroxy-2-methyl-1H-indol-3-yl)-N,N- dimethylbenzenesulfonamide::US10717733, Compound 37::US11098045, Compound 37 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454244 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454244&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302576 440970124 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081075 CN(c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O)S(C)(=O)=O InChI=1S/C22H24FN3O4S/c1-14-21(15-5-4-6-18(11-15)25(2)31(3,29)30)19-12-16(22(27)28)7-8-20(19)26(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H,27,28)/b17-9- AWHJWMCKUCEZQN-MFOYZWKCSA-N 454245 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-2- methyl-3-(3-(N- methylmethylsulfonamido)phenyl)-1H- indole-5-carboxylic acid::US10717733, Compound 38::US11098045, Compound 38 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454245 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454245&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340360 440970125 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081077 CN(C)C(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)N(C)S(C)(=O)=O)c2c1 InChI=1S/C24H29FN4O3S/c1-16-23(17-7-6-8-20(13-17)28(4)33(5,31)32)21-14-18(24(30)27(2)3)9-10-22(21)29(16)15-19(25)11-12-26/h6-11,13-14H,12,15,26H2,1-5H3/b19-11- VMMRBXSHHGEQJL-ODLFYWEKSA-N 454246 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)- N,N,2-trimethyl-3-(3-(N- methylmethylsulfonamido)phenyl)-1H- indole-5-carboxamide::US10717733, Compound 39::US11098045, Compound 39 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454246 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454246&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340361 440970126 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081079 CN(C)S(=O)(=O)c1cncc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O InChI=1S/C21H23FN4O4S/c1-13-20(15-8-17(11-24-10-15)31(29,30)25(2)3)18-9-14(21(27)28)4-5-19(18)26(13)12-16(22)6-7-23/h4-6,8-11H,7,12,23H2,1-3H3,(H,27,28)/b16-6- OFAYGIARESMFII-SOFYXZRVSA-N 454247 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (5-(N,N-dimethylsulfamoyl)pyridin-3-yl)- 2-methyl-1H-indole-5-carboxylic acid::US10717733, Compound 40::US11098045, Compound 40 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454247&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340661 440970127 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081081 CN(C)C(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cncc(c3)S(=O)(=O)N(C)C)c2c1 InChI=1S/C23H28FN5O3S/c1-15-22(17-10-19(13-26-12-17)33(31,32)28(4)5)20-11-16(23(30)27(2)3)6-7-21(20)29(15)14-18(24)8-9-25/h6-8,10-13H,9,14,25H2,1-5H3/b18-8- QYOGHIVVCYVEFQ-LSCVHKIXSA-N 454248 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (5-(N,N-dimethylsulfamoyl)pyridin-3-yl)- N,N,2-trimethyl-1H-indole-5-carboxamide::US10717733, Compound 41::US11098045, Compound 41 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454248 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454248&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130341090 440970128 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081083 CCOC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2n1 InChI=1S/C23H27FN4O4S/c1-5-32-23(29)19-9-10-20-22(26-19)21(15(2)28(20)14-17(24)11-12-25)16-7-6-8-18(13-16)33(30,31)27(3)4/h6-11,13H,5,12,14,25H2,1-4H3/b17-11- GPMKXMJMTMCLLA-BOPFTXTBSA-N 454249 (Z)-ethyl 1-(4-amino-2-fluorobut-2-en-1- yl)-3-(3-(N,N-dimethylsulfamoyl)phenyl- 2-methyl-1H-pyrrolo[3,2-b]pyridine-5- carboxylate::US10717733, Compound 42::US11098045, Compound 42 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454249 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454249&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340615 440970129 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081085 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(nc12)C(O)=O InChI=1S/C21H23FN4O4S/c1-13-19(14-5-4-6-16(11-14)31(29,30)25(2)3)20-18(8-7-17(24-20)21(27)28)26(13)12-15(22)9-10-23/h4-9,11H,10,12,23H2,1-3H3,(H,27,28)/b15-9- UORJLETWCVEPJY-DHDCSXOGSA-N 454250 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)-2- methyl-1H-pyrrolo[3,2-b]pyridine-5- carboxylic acid::US10717733, Compound 43::US11098045, Compound 43 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454250 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454250&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340616 440970130 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081087 CN(C)C(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2n1 InChI=1S/C23H28FN5O3S/c1-15-21(16-7-6-8-18(13-16)33(31,32)28(4)5)22-20(29(15)14-17(24)11-12-25)10-9-19(26-22)23(30)27(2)3/h6-11,13H,12,14,25H2,1-5H3/b17-11- ZCENNGVQLLWGOA-BOPFTXTBSA-N 454251 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)- N,N,2-trimethyl-1H-pyrrolo[3,2- b]pyridine-5-carboxamide::US10717733, Compound 44::US10717733, Compound 53::US11098045, Compound 53 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454251 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454251&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302714 440970131 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081089 CC(C)NC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2n1 InChI=1S/C24H30FN5O3S/c1-15(2)27-24(31)20-9-10-21-23(28-20)22(16(3)30(21)14-18(25)11-12-26)17-7-6-8-19(13-17)34(32,33)29(4)5/h6-11,13,15H,12,14,26H2,1-5H3,(H,27,31)/b18-11- NNNIZIIPUJHYKF-WQRHYEAKSA-N 454252 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)-N- isopropyl-2-methyl-1H-pyrrolo[3,2- b]pyridine-5-carboxamide::US10717733, Compound 45::US11098045, Compound 45 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454252 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454252&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302795 440970132 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081091 CNC(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2n1 InChI=1S/C22H26FN5O3S/c1-14-20(15-6-5-7-17(12-15)32(30,31)27(3)4)21-19(28(14)13-16(23)10-11-24)9-8-18(26-21)22(29)25-2/h5-10,12H,11,13,24H2,1-4H3,(H,25,29)/b16-10- CNOSXHWIAUWTRO-YBEGLDIGSA-N 454253 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)-N,2- dimethyl-1H-pyrrolo[3,2-b]pyridine-5- carboxamide::US10717733, Compound 46::US11098045, Compound 46 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454253 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454253&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340386 440970133 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081093 CN(C)C(=O)c1cccc2c(c(C)n(C\C(F)=C\CN)c12)-c1cccc(c1)S(=O)(=O)N(C)C InChI=1S/C24H29FN4O3S/c1-16-22(17-8-6-9-19(14-17)33(31,32)28(4)5)20-10-7-11-21(24(30)27(2)3)23(20)29(16)15-18(25)12-13-26/h6-12,14H,13,15,26H2,1-5H3/b18-12- SNHOXOFEINYVMA-PDGQHHTCSA-N 454254 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)- N,N,2-trimethyl-1H-indole-7-carboxamide::US10717733, Compound 47::US11098045, Compound 47 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454254&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340383 440970134 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081095 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2c(cccc12)C(O)=O InChI=1S/C22H24FN3O4S/c1-14-20(15-6-4-7-17(12-15)31(29,30)25(2)3)18-8-5-9-19(22(27)28)21(18)26(14)13-16(23)10-11-24/h4-10,12H,11,13,24H2,1-3H3,(H,27,28)/b16-10- AEPLTXCPSKDZBR-YBEGLDIGSA-N 454255 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)-2- methyl-1H-indole-7-carboxylic acid::US10717733, Compound 48::US11098045, Compound 48 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454255 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454255&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340617 440970135 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081097 COc1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2c1 InChI=1S/C22H26FN3O3S/c1-15-22(16-6-5-7-19(12-16)30(27,28)25(2)3)20-13-18(29-4)8-9-21(20)26(15)14-17(23)10-11-24/h5-10,12-13H,11,14,24H2,1-4H3/b17-10- MMCWIOMFLQMOQR-YVLHZVERSA-N 454256 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-methoxy-2-methyl-1H-indol-3-yl)-N,N- dimethylbenzenesulfonamide::US10717733, Compound 49::US11098045, Compound 49 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454256&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340619 440970136 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081099 CN(C)C(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(C)(=O)=O)c2c1 InChI=1S/C23H26FN3O3S/c1-15-22(16-6-5-7-19(12-16)31(4,29)30)20-13-17(23(28)26(2)3)8-9-21(20)27(15)14-18(24)10-11-25/h5-10,12-13H,11,14,25H2,1-4H3/b18-10- VHQUEPCPKULQLT-ZDLGFXPLSA-N 454257 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)- N,N,2-trimethyl-3-(3- (methylsulfonyl)phenyl)-1H-indole-5- carboxamide::US10717733, Compound 50::US11098045, Compound 50 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454257&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340730 440970137 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081101 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C#N InChI=1S/C22H23FN4O2S/c1-15-22(17-5-4-6-19(12-17)30(28,29)26(2)3)20-11-16(13-25)7-8-21(20)27(15)14-18(23)9-10-24/h4-9,11-12H,10,14,24H2,1-3H3/b18-9- IDNUNCWRGCTLCS-NVMNQCDNSA-N 454258 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-cyano-2-methyl-1H-indol-3-yl)-N,N- dimethylbenzenesulfonamide::US10717733, Compound 51::US11098045, Compound 51 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454258 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454258&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302582 440970138 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081103 CN(C)C(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2c1 InChI=1S/C24H29FN4O3S/c1-16-23(17-7-6-8-20(13-17)33(31,32)28(4)5)21-14-18(24(30)27(2)3)9-10-22(21)29(16)15-19(25)11-12-26/h6-11,13-14H,12,15,26H2,1-5H3/b19-11- NJTKSIQWDDYXEM-ODLFYWEKSA-N 454213 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)- N,N,2-trimethyl-1H-indole-5-carboxamide::US10717733, Compound 52::US10717733, Compound 6::US11098045, Compound 52 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454213&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302612 440970093 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081105 CN(C)C(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2n1 InChI=1S/C23H28FN5O3S/c1-15-21(16-7-6-8-18(13-16)33(31,32)28(4)5)22-20(29(15)14-17(24)11-12-25)10-9-19(26-22)23(30)27(2)3/h6-11,13H,12,14,25H2,1-5H3/b17-11- ZCENNGVQLLWGOA-BOPFTXTBSA-N 454251 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)- N,N,2-trimethyl-1H-pyrrolo[3,2- b]pyridine-5-carboxamide::US10717733, Compound 44::US10717733, Compound 53::US11098045, Compound 53 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454251 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454251&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302714 440970131 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081107 CN(C)C(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(N)(=O)=O)c2c1 InChI=1S/C22H25FN4O3S/c1-14-21(15-5-4-6-18(11-15)31(25,29)30)19-12-16(22(28)26(2)3)7-8-20(19)27(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H2,25,29,30)/b17-9- CICGNEQHRCXYPB-MFOYZWKCSA-N 454261 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)- N,N,2-trimethyl-3-(3-sulfamoylphenyl)- 1H-indole-5-carboxamide::US10717733, Compound 54::US11098045, Compound 54 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454261 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454261&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302650 440970139 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081109 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)-c1ncon1 InChI=1S/C23H24FN5O3S/c1-15-22(16-5-4-6-19(11-16)33(30,31)28(2)3)20-12-17(23-26-14-32-27-23)7-8-21(20)29(15)13-18(24)9-10-25/h4-9,11-12,14H,10,13,25H2,1-3H3/b18-9- QSNLOFPNPBRZAJ-NVMNQCDNSA-N 454262 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2-methyl-5-(1,2,4-oxadiazol-3-yl)-1H- indol-3-yl)-N,N- dimethylbenzenesulfonamide::US10717733, Compound 55::US11098045, Compound 55 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454262 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454262&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302689 440970140 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081111 CN(C)C(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)C(F)(F)F)c2c1 InChI=1S/C23H23F4N3O/c1-14-21(15-5-4-6-17(11-15)23(25,26)27)19-12-16(22(31)29(2)3)7-8-20(19)30(14)13-18(24)9-10-28/h4-9,11-12H,10,13,28H2,1-3H3/b18-9- DLAGRBXZINHTKW-NVMNQCDNSA-N 454263 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)- N,N,2-trimethyl-3-(3- (trifluoromethyl)phenyl)-1H-indole-5- carboxamide::US10717733, Compound 56::US11098045, Compound 56 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454263 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454263&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340278 440970141 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081113 CN(C)C(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)C(F)(F)F)c2c1 InChI=1S/C23H23F4N3O3S/c1-14-21(15-5-4-6-18(11-15)34(32,33)23(25,26)27)19-12-16(22(31)29(2)3)7-8-20(19)30(14)13-17(24)9-10-28/h4-9,11-12H,10,13,28H2,1-3H3/b17-9- FEHDFLZXUYTLKR-MFOYZWKCSA-N 454264 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)- N,N,2-trimethyl-3-(3- ((trifluoromethyl)sulfonyl)phenyl)-1H- indole-5-carboxamide::US10717733, Compound 57::US11098045, Compound 57 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454264 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454264&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302645 440970142 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081115 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)S(=O)(=O)N(C)C InChI=1S/C23H29FN4O4S2/c1-16-23(17-7-6-8-19(13-17)33(29,30)26(2)3)21-14-20(34(31,32)27(4)5)9-10-22(21)28(16)15-18(24)11-12-25/h6-11,13-14H,12,15,25H2,1-5H3/b18-11- HZZNVSRPZUPPMJ-WQRHYEAKSA-N 454265 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (3-(N,N-dimethylsulfamoyl)phenyl)- N,N,2-trimethyl-1H-indole-5-sulfonamide::US10717733, Compound 58::US11098045, Compound 58 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454265 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454265&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340927 440970143 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081117 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(F)F InChI=1S/C22H24F3N3O2S/c1-14-21(15-5-4-6-18(11-15)31(29,30)27(2)3)19-12-16(22(24)25)7-8-20(19)28(14)13-17(23)9-10-26/h4-9,11-12,22H,10,13,26H2,1-3H3/b17-9- QAFDQOGRSXZVEP-MFOYZWKCSA-N 454266 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-(difluoromethyl)-2-methyl-1H-indol-3- yl)-N,N-dimethylbenzene-sulfonamide::US10717733, Compound 59::US11098045, Compound 59 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454266 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454266&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302565 440970144 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081119 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(O)nc12 InChI=1S/C20H23FN4O3S/c1-13-19(14-5-4-6-16(11-14)29(27,28)24(2)3)20-17(7-8-18(26)23-20)25(13)12-15(21)9-10-22/h4-9,11H,10,12,22H2,1-3H3,(H,23,26)/b15-9- RUJYRUBFVZJLCY-DHDCSXOGSA-N 454267 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-hydroxy-2-methyl-1H-pyrrolo[3,2- b]pyridin-3-yl)-N,N-dimethylbenzene- sulfonamide::US10717733, Compound 60::US11098045, Compound 60 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454267 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454267&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302546 440970145 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081121 COc1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2n1 InChI=1S/C21H25FN4O3S/c1-14-20(15-6-5-7-17(12-15)30(27,28)25(2)3)21-18(8-9-19(24-21)29-4)26(14)13-16(22)10-11-23/h5-10,12H,11,13,23H2,1-4H3/b16-10- GFVITOWSGPXAGC-YBEGLDIGSA-N 454268 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-methoxy-2-methyl-1H-pyrrolo[3,2- b]pyridin-3-yl)-N,N-dimethylbenzene- sulfonamide::US10717733, Compound 61::US11098045, Compound 61 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454268 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454268&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302708 440970146 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081123 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(Cl)cc12 InChI=1S/C21H23ClFN3O2S/c1-14-21(15-5-4-6-18(11-15)29(27,28)25(2)3)19-12-16(22)7-8-20(19)26(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3/b17-9- GDLVXWLFNXIEER-MFOYZWKCSA-N 454269 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-chloro-2-methyl-1H-indol-3-yl)-N,N- dimethylbenzenesulfonamide::US10717733, Compound 62::US11098045, Compound 62 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454269 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454269&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302766 440970147 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081125 CN(C)S(=O)(=O)c1cncc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccccc12 InChI=1S/C20H23FN4O2S/c1-14-20(15-10-17(12-23-11-15)28(26,27)24(2)3)18-6-4-5-7-19(18)25(14)13-16(21)8-9-22/h4-8,10-12H,9,13,22H2,1-3H3/b16-8- YRTJAKHAIIIFHD-PXNMLYILSA-N 454270 (Z)-5-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2-methyl-1H-indol-3-yl)-N,N- dimethylpyridine-3-sulfonamide::US10717733, Compound 63::US11098045, Compound 63 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454270 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454270&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302695 440970148 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081127 CN(C)S(=O)(=O)c1cncc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(Cl)cc12 InChI=1S/C20H22ClFN4O2S/c1-13-20(14-8-17(11-24-10-14)29(27,28)25(2)3)18-9-15(21)4-5-19(18)26(13)12-16(22)6-7-23/h4-6,8-11H,7,12,23H2,1-3H3/b16-6- YJGKFXFYARFULF-SOFYXZRVSA-N 454271 (Z)-5-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-chloro-2-methyl-1H-indol-3-yl)-N,N- dimethylpyridine-3-sulfonamide::US10717733, Compound 64::US11098045, Compound 64 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454271 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454271&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302671 440970149 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081129 Cc1c(-c2cncc(c2)S(C)(=O)=O)c2cc(Cl)ccc2n1C\C(F)=C\CN InChI=1S/C19H19ClFN3O2S/c1-12-19(13-7-16(10-23-9-13)27(2,25)26)17-8-14(20)3-4-18(17)24(12)11-15(21)5-6-22/h3-5,7-10H,6,11,22H2,1-2H3/b15-5- LYXQDOCFRZPEMI-WCSRMQSCSA-N 454272 (Z)-4-(5-chloro-2-methyl-3-(5- (methylsulfonyl)pyridin-3-yl)-1H-indol-1- yl)-3-fluorobut-2-en-1-amine::US10717733, Compound 65::US11098045, Compound 65 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454272 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454272&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340721 440970150 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081131 CN(C)S(=O)(=O)c1cncc(c1)-c1cn(C\C(F)=C\CN)c2ccc(Cl)cc12 InChI=1S/C19H20ClFN4O2S/c1-24(2)28(26,27)16-7-13(9-23-10-16)18-12-25(11-15(21)5-6-22)19-4-3-14(20)8-17(18)19/h3-5,7-10,12H,6,11,22H2,1-2H3/b15-5- IPTVKPDQJDWFRX-WCSRMQSCSA-N 454273 (Z)-5-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-chloro-1H-indol-3-yl)-N,N- dimethylpyridine-3-sulfonamide::US10717733, Compound 66::US11098045, Compound 66 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454273 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454273&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302693 440970151 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081133 CN(C)S(=O)(=O)c1cncc(c1)-c1c(C)n(C\C(F)=C\CN)c2cc(Cl)ccc12 InChI=1S/C20H22ClFN4O2S/c1-13-20(14-8-17(11-24-10-14)29(27,28)25(2)3)18-5-4-15(21)9-19(18)26(13)12-16(22)6-7-23/h4-6,8-11H,7,12,23H2,1-3H3/b16-6- WMRDUKQHVNVGMA-SOFYXZRVSA-N 454274 (Z)-5-(1-(4-amino-2-fluorobut-2-en-l-yl)- 6-chloro-2-methyl-1H-indol-3-yl)-N,N- dimethylpyridine-3-sulfonamide::US10717733, Compound 67::US11098045, Compound 67 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454274 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454274&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302614 440970152 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081135 COc1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(SC)c3)c2n1 InChI=1S/C20H22FN3OS/c1-13-19(14-5-4-6-16(11-14)26-3)20-17(7-8-18(23-20)25-2)24(13)12-15(21)9-10-22/h4-9,11H,10,12,22H2,1-3H3/b15-9- KMSZGJIQCLEWBE-DHDCSXOGSA-N 454275 (Z)-3-fluoro-4-(5-methoxy-2-methyl-3-(3- (methylthio)phenyl)-1H-pyrrolo[3,2- b]pyridin-1-yl)but-2-en-1-amine::US10717733, Compound 68::US11098045, Compound 68 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454275 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454275&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340813 440970153 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081137 COc1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(C)(=O)=O)c2n1 InChI=1S/C20H22FN3O3S/c1-13-19(14-5-4-6-16(11-14)28(3,25)26)20-17(7-8-18(23-20)27-2)24(13)12-15(21)9-10-22/h4-9,11H,10,12,22H2,1-3H3/b15-9- LONHJBOQCASDGC-DHDCSXOGSA-N 454276 (Z)-3-fluoro-4-(5-methoxy-2-methyl-3-(3- (methylsulfonyl)phenyl)-1H-pyrrolo[3,2- b]pyridin-1-yl)but-2-en-1-amine::US10717733, Compound 69::US11098045, Compound 69 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454276 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454276&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340812 440970154 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081139 CNS(=O)(=O)c1cncc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(Cl)cc12 InChI=1S/C19H20ClFN4O2S/c1-12-19(13-7-16(10-24-9-13)28(26,27)23-2)17-8-14(20)3-4-18(17)25(12)11-15(21)5-6-22/h3-5,7-10,23H,6,11,22H2,1-2H3/b15-5- AIRDSXKULYLFHT-WCSRMQSCSA-N 454277 (Z)-5-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-chloro-2-methyl-1H-indol-3-yl)-N- methylpyridine-3-sulfonamide::US10717733, Compound 70::US11098045, Compound 70 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454277 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454277&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302737 440970155 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081141 CN(C)S(=O)(=O)c1cncc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(F)cc12 InChI=1S/C20H22F2N4O2S/c1-13-20(14-8-17(11-24-10-14)29(27,28)25(2)3)18-9-15(21)4-5-19(18)26(13)12-16(22)6-7-23/h4-6,8-11H,7,12,23H2,1-3H3/b16-6- VGFSHMFFCDJALG-SOFYXZRVSA-N 454278 (Z)-5-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-fluoro-2-methyl-1H-indol-3-yl)-N,N- dimethylpyridine-3-sulfonamide::US10717733, Compound 71::US11098045, Compound 71 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454278 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454278&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130341152 440970156 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081143 CN(C)S(=O)(=O)c1cncc(c1)-c1c(C)n(C\C(F)=C\CN)c2cc(Cl)cnc12 InChI=1S/C19H21ClFN5O2S/c1-12-18(13-6-16(10-23-8-13)29(27,28)25(2)3)19-17(7-14(20)9-24-19)26(12)11-15(21)4-5-22/h4,6-10H,5,11,22H2,1-3H3/b15-4- SBPPRHMQFPOAQA-TVPGTPATSA-N 454279 (Z)-5-(1-(4-amino-2-fluorobut-2-en-1-yl)- 6-chloro-2-methyl-1H-pyrrolo[3,2- b]pyridin-3-yl)-N,N-dimethylpyridine-3- sulfonamide::US10717733, Compound 72::US11098045, Compound 72 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454279 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454279&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130341153 440970157 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081145 CN(C)S(=O)(=O)c1cncc(c1)-c1c(C)n(C\C(F)=C\CN)c2ncc(Cl)cc12 InChI=1S/C19H21ClFN5O2S/c1-12-18(13-6-16(10-23-8-13)29(27,28)25(2)3)17-7-14(20)9-24-19(17)26(12)11-15(21)4-5-22/h4,6-10H,5,11,22H2,1-3H3/b15-4- BAHGGRQZWUCPLS-TVPGTPATSA-N 454280 (Z)-5-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-chloro-2-methyl-1H-pyrrolo[2,3- b]pyridin-3-yl)-N,N-dimethylpyridine-3- sulfonamide::US10717733, Compound 73::US11098045, Compound 73 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454280 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454280&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130341151 440970158 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081147 CN(C)S(=O)(=O)c1cncc(c1)-c1c(C)n(C\C(F)=C\CN)c2c(Cl)cccc12 InChI=1S/C20H22ClFN4O2S/c1-13-19(14-9-16(11-24-10-14)29(27,28)25(2)3)17-5-4-6-18(21)20(17)26(13)12-15(22)7-8-23/h4-7,9-11H,8,12,23H2,1-3H3/b15-7- DMQBNXWLVZYSHY-CHHVJCJISA-N 454281 (Z)-5-(1-(4-amino-2-fluorobut-2-en-1-yl)- 7-chloro-2-methyl-1H-indol-3-yl)-N,N- dimethylpyridine-3-sulfonamide::US10717733, Compound 74::US11098045, Compound 74 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454281 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454281&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302749 440970159 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081149 CN(C)S(=O)(=O)c1cncc(c1)-c1c(C)n(C\C(F)=C\CN)c2cccc(Cl)c12 InChI=1S/C20H22ClFN4O2S/c1-13-19(14-9-16(11-24-10-14)29(27,28)25(2)3)20-17(21)5-4-6-18(20)26(13)12-15(22)7-8-23/h4-7,9-11H,8,12,23H2,1-3H3/b15-7- BGUIUILVCOCCOJ-CHHVJCJISA-N 454282 (Z)-5-(1-(4-amino-2-fluorobut-2-en-1-yl)- 4-chloro-2-methyl-1H-indol-3-yl)-N,N- dimethylpyridine-3-sulfonamide::US10717733, Compound 75::US11098045, Compound 75 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454282 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454282&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302604 440970160 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081151 Cc1c(-c2ccncc2)c2cc(Cl)ccc2n1C\C(F)=C\CN InChI=1S/C18H17ClFN3/c1-12-18(13-5-8-22-9-6-13)16-10-14(19)2-3-17(16)23(12)11-15(20)4-7-21/h2-6,8-10H,7,11,21H2,1H3/b15-4- RTJBWWUDJSWTAR-TVPGTPATSA-N 454283 (Z)-4-(5-chloro-2-methyl-3-(pyridin-4-yl)- 1H-indol-1-yl)-3-fluorobut-2-en-1-amine::US10717733, Compound 76::US11098045, Compound 76 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454283 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454283&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340808 440970161 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081153 Cc1c(-c2cccnc2)c2cc(Cl)ccc2n1C\C(F)=C\CN InChI=1S/C18H17ClFN3/c1-12-18(13-3-2-8-22-10-13)16-9-14(19)4-5-17(16)23(12)11-15(20)6-7-21/h2-6,8-10H,7,11,21H2,1H3/b15-6- RMTFSHKGTBCWAW-UUASQNMZSA-N 454284 (Z)-4-(5-chloro-2-methyl-3-(pyridin-3-yl)- 1H-indol-1-yl)-3-fluorobut-2-en-1-amine::US10717733, Compound 77::US11098045, Compound 77 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454284 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454284&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302625 440970162 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081155 CN(C)S(=O)(=O)c1cccc(n1)-c1c(C)n(C\C(F)=C\CN)c2ccc(Cl)cc12 InChI=1S/C20H22ClFN4O2S/c1-13-20(17-5-4-6-19(24-17)29(27,28)25(2)3)16-11-14(21)7-8-18(16)26(13)12-15(22)9-10-23/h4-9,11H,10,12,23H2,1-3H3/b15-9- HRGFULBVHRNBTG-DHDCSXOGSA-N 454285 (Z)-6-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-chloro-2-methyl-1H-indol-3-yl)-N,N- dimethylpyridine-2-sulfonamide::US10717733, Compound 78::US11098045, Compound 78 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454285 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454285&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302730 440970163 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081157 CN(C)S(=O)(=O)c1cncc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C1CC1 InChI=1S/C23H27FN4O2S/c1-15-23(18-10-20(13-26-12-18)31(29,30)27(2)3)21-11-17(16-4-5-16)6-7-22(21)28(15)14-19(24)8-9-25/h6-8,10-13,16H,4-5,9,14,25H2,1-3H3/b19-8- WRZUTJXQDIEVCW-UWVJOHFNSA-N 454286 (Z)-5-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-cyclopropyl-2-methyl-1H-indol-3-yl)- N,N-dimethylpyridine-3-sulfonamide::US10717733, Compound 79::US11098045, Compound 79 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454286 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454286&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302778 440970164 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081159 Cc1c(-c2cncnc2)c2cc(Cl)ccc2n1C\C(F)=C\CN InChI=1S/C17H16ClFN4/c1-11-17(12-7-21-10-22-8-12)15-6-13(18)2-3-16(15)23(11)9-14(19)4-5-20/h2-4,6-8,10H,5,9,20H2,1H3/b14-4- PBOOZGOWDGVWFI-CPSFFCFKSA-N 454287 (Z)-4-(5-chloro-2-methyl-3-(pyrimidin-5- yl)-1H-indol-1-yl)-3-fluorobut-2-en-1- amine::US10717733, Compound 80::US11098045, Compound 80 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454287 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454287&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302636 440970165 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081161 CN(C)S(=O)(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3ccncc3)c2c1 InChI=1S/C20H23FN4O2S/c1-14-20(15-7-10-23-11-8-15)18-12-17(28(26,27)24(2)3)4-5-19(18)25(14)13-16(21)6-9-22/h4-8,10-12H,9,13,22H2,1-3H3/b16-6- OZLSSHJXSURSTI-SOFYXZRVSA-N 454288 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)- N,N,2-trimethyl-3-(pyridin-4-yl)-1H- indole-5-sulfonamide::US10717733, Compound 81::US11098045, Compound 81 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454288 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454288&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302643 440970166 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081163 CN(C)S(=O)(=O)c1ccc(C)c(c1)-c1c(C)n(C\C(F)=C\CN)c2c(F)cc(Cl)cc12 InChI=1S/C22H24ClF2N3O2S/c1-13-5-6-17(31(29,30)27(3)4)11-18(13)21-14(2)28(12-16(24)7-8-26)22-19(21)9-15(23)10-20(22)25/h5-7,9-11H,8,12,26H2,1-4H3/b16-7- PUUTWSFCFSHISQ-APSNUPSMSA-N 454289 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-chloro-7-fluoro-2-methyl-1H-indol-3- yl)-N,N,4-trimethylbenzenesulfonamide::US10717733, Compound 82::US11098045, Compound 82 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454289&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302722 440970167 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081165 Cc1c(-c2cncc(c2)S(N)(=O)=O)c2cc(Cl)ccc2n1C\C(F)=C\CN InChI=1S/C18H18ClFN4O2S/c1-11-18(12-6-15(9-23-8-12)27(22,25)26)16-7-13(19)2-3-17(16)24(11)10-14(20)4-5-21/h2-4,6-9H,5,10,21H2,1H3,(H2,22,25,26)/b14-4- ALOYLRIYXMBLRE-CPSFFCFKSA-N 454290 (Z)-5-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-chloro-2-methyl-1H-indol-3- yl)pyridine-3-sulfonamide::US10717733, Compound 83::US11098045, Compound 83 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454290&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302607 440970168 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081167 Cc1c(-c2ccncc2)c2cc(ccc2n1C\C(F)=C\CN)S(N)(=O)=O InChI=1S/C18H19FN4O2S/c1-12-18(13-5-8-22-9-6-13)16-10-15(26(21,24)25)2-3-17(16)23(12)11-14(19)4-7-20/h2-6,8-10H,7,11,20H2,1H3,(H2,21,24,25)/b14-4- DIOYUFSKSAVHOY-CPSFFCFKSA-N 454291 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-2- methyl-3-(pyridin-4-yl)-1H-indole-5- sulfonamide::US10717733, Compound 84::US11098045, Compound 84 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454291 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454291&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130341091 440970169 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081169 CN(C)S(=O)(=O)c1cncc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(OC(F)(F)F)cc12 InChI=1S/C21H22F4N4O3S/c1-13-20(14-8-17(11-27-10-14)33(30,31)28(2)3)18-9-16(32-21(23,24)25)4-5-19(18)29(13)12-15(22)6-7-26/h4-6,8-11H,7,12,26H2,1-3H3/b15-6- QHPTXOQKFWZNAU-UUASQNMZSA-N 454292 (Z)-5-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2-methyl-5-(trifluoromethoxy)-1H-indol- 3-yl)-N,N-dimethylpyridine-3- sulfonamide::US10717733, Compound 85::US11098045, Compound 85 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454292 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454292&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340694 440970170 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081171 CN(C)S(=O)(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3ccccc3)c2c1 InChI=1S/C21H24FN3O2S/c1-15-21(16-7-5-4-6-8-16)19-13-18(28(26,27)24(2)3)9-10-20(19)25(15)14-17(22)11-12-23/h4-11,13H,12,14,23H2,1-3H3/b17-11- PAEBSSCCJBOUPY-BOPFTXTBSA-N 454293 (Z,)-1-(4-amino-2-fluorobut-2-en-1-yl)- N,N,2-trimethyl-3-phenyl-1H-indole-5- sulfonamide::US10717733, Compound 86::US11098045, Compound 86 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454293&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 140959835 440970171 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081173 Cc1c(-c2ccccc2)c2cc(ccc2n1C\C(F)=C\CN)S(C)(=O)=O InChI=1S/C20H21FN2O2S/c1-14-20(15-6-4-3-5-7-15)18-12-17(26(2,24)25)8-9-19(18)23(14)13-16(21)10-11-22/h3-10,12H,11,13,22H2,1-2H3/b16-10- VVUZMZSGTNBEMW-YBEGLDIGSA-N 454294 (Z)-3-fluoro-4-(2-methyl-5- (methylsulfonyl)-3-phenyl-1H-indol-1- yl)but-2-en-1-amine::US10717733, Compound 87::US11098045, Compound 87 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454294 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454294&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302599 440970172 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081175 Cc1c(-c2ccncc2)c2cc(ccc2n1C\C(F)=C\CN)S(C)(=O)=O InChI=1S/C19H20FN3O2S/c1-13-19(14-6-9-22-10-7-14)17-11-16(26(2,24)25)3-4-18(17)23(13)12-15(20)5-8-21/h3-7,9-11H,8,12,21H2,1-2H3/b15-5- RKIUZNHFBMWLKB-WCSRMQSCSA-N 454295 (Z)-3-fluoro-4-(2-methyl-5- (methylsulfonyl)-3-(pyridin-4-yl)-1H- indol-1-yl)but-2-en-1-amine::US10717733, Compound 88::US11098045, Compound 88 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454295 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454295&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340618 440970173 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081177 Cc1c(-c2cc(C)nc(C)c2)c2cc(ccc2n1C\C(F)=C\CN)S(C)(=O)=O InChI=1S/C21H24FN3O2S/c1-13-9-16(10-14(2)24-13)21-15(3)25(12-17(22)7-8-23)20-6-5-18(11-19(20)21)28(4,26)27/h5-7,9-11H,8,12,23H2,1-4H3/b17-7- YXVDHWKOLDGTAF-IDUWFGFVSA-N 454296 (Z)-4-(3-(2,6-dimethylpyridin-4-yl)-2- methyl-5-(methylsulfonyl)-1H-indol-1- yl)-3-fluorobut-2-en-1-amine::US10717733, Compound 89::US11098045, Compound 89 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454296&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302706 440970174 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081179 CN(C)C(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cc(C)nc(C)c3)c2c1 InChI=1S/C23H27FN4O/c1-14-10-18(11-15(2)26-14)22-16(3)28(13-19(24)8-9-25)21-7-6-17(12-20(21)22)23(29)27(4)5/h6-8,10-12H,9,13,25H2,1-5H3/b19-8- JNYPGWNXROHHDU-UWVJOHFNSA-N 454297 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (2,6-dimethylpyridin-4-yl)-N,N,2- trimethyl-1H-indole-5-carboxamide::US10717733, Compound 90::US11098045, Compound 90 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454297 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454297&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302718 440970175 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081181 Cc1c(-c2ccncc2)c2cc(ccc2n1C\C(F)=C\CN)C(=O)NC(C)(C)C InChI=1S/C23H27FN4O/c1-15-21(16-8-11-26-12-9-16)19-13-17(22(29)27-23(2,3)4)5-6-20(19)28(15)14-18(24)7-10-25/h5-9,11-13H,10,14,25H2,1-4H3,(H,27,29)/b18-7- HNUNUFDNZBBBMV-WSVATBPTSA-N 454298 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-N- (tert-butyl)-2-methyl-3-(pyridin-4-yl)-1H- indole-5-carboxamide::US10717733, Compound 91::US11098045, Compound 91 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454298 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454298&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302679 440970176 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081183 Cc1c(-c2ccc3OCOc3c2)c2cc(ccc2n1C\C(F)=C\CN)S(C)(=O)=O InChI=1S/C21H21FN2O4S/c1-13-21(14-3-6-19-20(9-14)28-12-27-19)17-10-16(29(2,25)26)4-5-18(17)24(13)11-15(22)7-8-23/h3-7,9-10H,8,11-12,23H2,1-2H3/b15-7- NZCZZVYLRXZCSO-CHHVJCJISA-N 454299 (Z)-4-(3-(benzo[d][1,3]dioxol-5-yl)-2- methyl-5-(methylsulfonyl)-1H-indol-1- yl)-3-fluorobut-2-en-1-amine::US10717733, Compound 92::US11098045, Compound 92 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454299&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340975 440970177 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081185 Cc1c(-c2ccc(F)cc2)c2cc(ccc2n1C\C(F)=C\CN)S(C)(=O)=O InChI=1S/C20H20F2N2O2S/c1-13-20(14-3-5-15(21)6-4-14)18-11-17(27(2,25)26)7-8-19(18)24(13)12-16(22)9-10-23/h3-9,11H,10,12,23H2,1-2H3/b16-9- QVVSHBGWCLBQFS-SXGWCWSVSA-N 454300 (Z)-3-fluoro-4-(3-(4-fluorophenyl)-2- methyl-5-(methylsulfonyl)-1H-indol-1- yl)but-2-en-1-amine::US10717733, Compound 93::US11098045, Compound 93 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454300 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454300&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340381 440970178 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081187 Cc1c(-c2ccnc(C)c2)c2cc(ccc2n1C\C(F)=C\CN)S(C)(=O)=O InChI=1S/C20H22FN3O2S/c1-13-10-15(7-9-23-13)20-14(2)24(12-16(21)6-8-22)19-5-4-17(11-18(19)20)27(3,25)26/h4-7,9-11H,8,12,22H2,1-3H3/b16-6- QWPMTVONEHGSQW-SOFYXZRVSA-N 454301 (Z)-3-fluoro-4-(2-methyl-3-(2- methylpyridin-4-yl)-5-(methylsulfonyl)- 1H-indol-1-yl)but-2-en-l-amine::US10717733, Compound 94::US11098045, Compound 94 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454301 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454301&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340382 440970179 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081189 Cc1c(-c2ccc(F)cc2)c2cc(ccc2n1C\C(F)=C\CN)S(N)(=O)=O InChI=1S/C19H19F2N3O2S/c1-12-19(13-2-4-14(20)5-3-13)17-10-16(27(23,25)26)6-7-18(17)24(12)11-15(21)8-9-22/h2-8,10H,9,11,22H2,1H3,(H2,23,25,26)/b15-8- PPAMXDACGNFUAY-NVNXTCNLSA-N 454302 (Z)-1-(4-amino-2-fluorobut-2-en-1-yl)-3- (4-fluorophenyl)-2-methyl-1H-indole-5- sulfonamide::US10717733, Compound 95::US11098045, Compound 95 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454302 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454302&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340380 440970180 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081191 CN(C)S(=O)(=O)c1cncc(c1)-c1c(Cl)n(C\C(F)=C\CN)c2ccccc12 InChI=1S/C19H20ClFN4O2S/c1-24(2)28(26,27)15-9-13(10-23-11-15)18-16-5-3-4-6-17(16)25(19(18)20)12-14(21)7-8-22/h3-7,9-11H,8,12,22H2,1-2H3/b14-7- YZFJULKNOVCHHD-AUWJEWJLSA-N 454303 (Z)-5-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2-chloro-1H-indol-3-yl)-N,N- dimethylpyridine-3-sulfonamide::US10717733, Compound 96::US11098045, Compound 96 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454303 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454303&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302673 440970181 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081193 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)S(C)(=O)=O InChI=1S/C22H26FN3O4S2/c1-15-22(16-6-5-7-19(12-16)32(29,30)25(2)3)20-13-18(31(4,27)28)8-9-21(20)26(15)14-17(23)10-11-24/h5-10,12-13H,11,14,24H2,1-4H3/b17-10- WIUGYCXDLGMJMM-YVLHZVERSA-N 454304 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2-methyl-5-(methylsulfonyl)-1H-indol-3- yl)-N,N-dimethylbenzenesulfonamide::US10717733, Compound 97::US11098045, Compound 97 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454304 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454304&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340283 440970182 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081195 COc1cc(ccn1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)S(C)(=O)=O InChI=1S/C20H22FN3O3S/c1-13-20(14-7-9-23-19(10-14)27-2)17-11-16(28(3,25)26)4-5-18(17)24(13)12-15(21)6-8-22/h4-7,9-11H,8,12,22H2,1-3H3/b15-6- ZVNJXJYCLKMNIS-UUASQNMZSA-N 454305 (Z)-3-fluoro-4-(3-(2-methoxypyridin-4- yl)-2-methyl-5-(methylsulfonyl)-1H- indol-1-yl)but-2-en-1-amine::US10717733, Compound 98::US11098045, Compound 98 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454305 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454305&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340284 440970183 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081197 CN(C)S(=O)(=O)c1cccc(c1)-c1c(Cl)n(C\C(F)=C\CN)c2cccnc12 InChI=1S/C19H20ClFN4O2S/c1-24(2)28(26,27)15-6-3-5-13(11-15)17-18-16(7-4-10-23-18)25(19(17)20)12-14(21)8-9-22/h3-8,10-11H,9,12,22H2,1-2H3/b14-8- YJIHEXTWFQRSBT-ZSOIEALJSA-N 454306 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2-chloro-1H-pyrrolo[3,2-b]pyridin-3-yl)- N,N-dimethylbenzenesulfonamide::US10717733, Compound 99::US11098045, Compound 99 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454306 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454306&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302627 440970184 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081199 CN(C)S(=O)(=O)c1cccc(c1)-c1c(Cl)n(C\C(F)=C\CN)c2ccc(cc12)S(C)(=O)=O InChI=1S/C21H23ClFN3O4S2/c1-25(2)32(29,30)17-6-4-5-14(11-17)20-18-12-16(31(3,27)28)7-8-19(18)26(21(20)22)13-15(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3/b15-9- PPSPBSQSGKQUMI-DHDCSXOGSA-N 454307 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2-chloro-5-(methylsulfonyl)-1H-indol-3- yl)-N,N-dimethylbenzenesulfonamide::US10717733, Compound 100::US11098045, Compound 100 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454307 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454307&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340285 440970185 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081201 Cc1c(-c2cc(C)nc(C)c2)c2cc(ccc2n1C\C(F)=C\CN)[N+]([O-])=O InChI=1S/C20H21FN4O2/c1-12-8-15(9-13(2)23-12)20-14(3)24(11-16(21)6-7-22)19-5-4-17(25(26)27)10-18(19)20/h4-6,8-10H,7,11,22H2,1-3H3/b16-6- AIJWVRGDHRJJNV-SOFYXZRVSA-N 454308 (Z)-4-(3-(2,6-dimethylpyridin-4-yl)-2- methyl-5-nitro-1H-indol-1-yl)-3- fluorobut-2-en-1-amine::US10717733, Compound 101::US11098045, Compound 101 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454308 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454308&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340286 440970186 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081203 Cc1c(-c2cc(C)nc(C)c2)c2cc(NS(C)(=O)=O)ccc2n1C\C(F)=C\CN InChI=1S/C21H25FN4O2S/c1-13-9-16(10-14(2)24-13)21-15(3)26(12-17(22)7-8-23)20-6-5-18(11-19(20)21)25-29(4,27)28/h5-7,9-11,25H,8,12,23H2,1-4H3/b17-7- IKBVLJQUKOAAGC-IDUWFGFVSA-N 454309 (Z)-N-(1-(4-amino-2-fluorobut-2-en-1-yl)- 3-(2,6-dimethylpyridin-4-yl)-2-methyl- 1H-indol-5-yl)methanesulfonamide::US10717733, Compound 102::US11098045, Compound 102 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454309 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454309&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302712 440970187 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081205 COCc1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2n1 InChI=1S/C22H27FN4O3S/c1-15-21(16-6-5-7-19(12-16)31(28,29)26(2)3)22-20(9-8-18(25-22)14-30-4)27(15)13-17(23)10-11-24/h5-10,12H,11,13-14,24H2,1-4H3/b17-10- RYVSADMCIOYOQZ-YVLHZVERSA-N 454310 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-(methoxymethyl)-2-methyl-1H- pyrrolo[3,2-b]pyridin-3-yl)-N,N- dimethylbenzenesulfonamide::US10717733, Compound 103::US11098045, Compound 103 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454310 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454310&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130341128 440970188 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081207 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(NS(C)(=O)=O)cc12 InChI=1S/C22H27FN4O4S2/c1-15-22(16-6-5-7-19(12-16)33(30,31)26(2)3)20-13-18(25-32(4,28)29)8-9-21(20)27(15)14-17(23)10-11-24/h5-10,12-13,25H,11,14,24H2,1-4H3/b17-10- FHUDTBDZOLHKBL-YVLHZVERSA-N 454311 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2-methyl-5-(methylsulfonamido)-1H- indol-3-yl)-N,N- dimethylbenzenesulfonamide::US10717733, Compound 104::US11098045, Compound 104 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454311 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454311&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302697 440970189 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081209 CN(C)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2n1 InChI=1S/C22H28FN5O2S/c1-15-21(16-7-6-8-18(13-16)31(29,30)27(4)5)22-19(9-10-20(25-22)26(2)3)28(15)14-17(23)11-12-24/h6-11,13H,12,14,24H2,1-5H3/b17-11- RFHRANNTRQLTOA-BOPFTXTBSA-N 454312 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-(dimethylamino)-2-methyl-1H- pyrrolo[3,2-b]pyridin-3-yl)-N,N- dimethylbenzenesulfonamide::US10717733, Compound 105::US11098045, Compound 105 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454312 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454312&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302578 440970190 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081211 CC(C)S(=O)(=O)c1ccc2n(C\C(F)=C\CN)c(C)c(-c3cccc(c3)S(=O)(=O)N(C)C)c2c1 InChI=1S/C24H30FN3O4S2/c1-16(2)33(29,30)20-9-10-23-22(14-20)24(17(3)28(23)15-19(25)11-12-26)18-7-6-8-21(13-18)34(31,32)27(4)5/h6-11,13-14,16H,12,15,26H2,1-5H3/b19-11- YMDVIXFCDYEIOK-ODLFYWEKSA-N 454313 (Z)-3-(1-(4-amino-2-fluorobut-2-en-l-yl)- 5-(isopropylsulfonyl)-2-methyl-1H-indol- 3-yl)-N,N-dimethylbenzenesulfonamide::US10717733, Compound 106::US11098045, Compound 106 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454313 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454313&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302726 440970191 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081213 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(C)nc12 InChI=1S/C21H25FN4O2S/c1-14-8-9-19-21(24-14)20(15(2)26(19)13-17(22)10-11-23)16-6-5-7-18(12-16)29(27,28)25(3)4/h5-10,12H,11,13,23H2,1-4H3/b17-10- AQVVXVOWPOXVME-YVLHZVERSA-N 454314 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2,5-dimethyl-1H-pyrrolo[3,2-b]pyridin-3- yl)-N,N-dimethylbenzenesulfonamide::US10717733, Compound 107::US11098045, Compound 107 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454314&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340700 440970192 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081215 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2cc(F)cnc12 InChI=1S/C20H22F2N4O2S/c1-13-19(14-5-4-6-17(9-14)29(27,28)25(2)3)20-18(10-16(22)11-24-20)26(13)12-15(21)7-8-23/h4-7,9-11H,8,12,23H2,1-3H3/b15-7- GTWOFLYRSQOOCV-CHHVJCJISA-N 454315 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 6-fluoro-2-methyl-1H-pyrrolo[3,2- b]pyridin-3-yl)-N,N- dimethylbenzenesulfonamide::US10717733, Compound 108::US11098045, Compound 108 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454315 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454315&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302805 440970193 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081217 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(F)nc12 InChI=1S/C20H22F2N4O2S/c1-13-19(14-5-4-6-16(11-14)29(27,28)25(2)3)20-17(7-8-18(22)24-20)26(13)12-15(21)9-10-23/h4-9,11H,10,12,23H2,1-3H3/b15-9- GTHWWFKHEBCKQA-DHDCSXOGSA-N 454316 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-fluoro-2-methyl-1H-pyrrolo[3,2- b]pyridin-3-yl)-N,N- dimethylbenzenesulfonamide::US10717733, Compound 109::US11098045, Compound 109 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454316 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454316&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302799 440970194 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081219 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(nc12)C(F)(F)F InChI=1S/C21H22F4N4O2S/c1-13-19(14-5-4-6-16(11-14)32(30,31)28(2)3)20-17(29(13)12-15(22)9-10-26)7-8-18(27-20)21(23,24)25/h4-9,11H,10,12,26H2,1-3H3/b15-9- JKEQDBASFYMVAI-DHDCSXOGSA-N 454317 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 2-methyl-5-(trifluoromethyl)-1H- pyrrolo[3,2-b]pyridin-3-yl)-N,N- dimethylbenzenesulfonamide::US10717733, Compound 110::US11098045, Compound 110 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454317 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454317&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340701 440970195 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081221 CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(nc12)C(C)(F)F InChI=1S/C22H25F3N4O2S/c1-14-20(15-6-5-7-17(12-15)32(30,31)28(3)4)21-18(29(14)13-16(23)10-11-26)8-9-19(27-21)22(2,24)25/h5-10,12H,11,13,26H2,1-4H3/b16-10- NGRUWSPCBZSMMF-YBEGLDIGSA-N 454318 (Z)-3-(1-(4-amino-2-fluorobut-2-en-1-yl)- 5-(1,1-difluoroethyl)-2-methyl-1H- pyrrolo[3,2-b]pyridin-3-yl)-N,N- dimethylbenzenesulfonamide::US10717733, Compound 111::US11098045, Compound 111 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454318 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454318&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340723 440970196 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081223 Cc1c(-c2cccc(c2)S(C)(=O)=O)c2nc(C)ccc2n1C\C(F)=C\CN InChI=1S/C20H22FN3O2S/c1-13-7-8-18-20(23-13)19(14(2)24(18)12-16(21)9-10-22)15-5-4-6-17(11-15)27(3,25)26/h4-9,11H,10,12,22H2,1-3H3/b16-9- NYZBHVWJAALINP-SXGWCWSVSA-N 454319 (Z)-4-(2,5-dimethyl-3-(3- (methylsulfonyl)phenyl)-1H-pyrrolo[3,2- b]pyridin-1-yl)-3-fluorobut-2-en-1-amine::US10717733, Compound 112::US11098045, Compound 112 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454319 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454319&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130338729 440970197 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081225 CCS(=O)(=O)c1cccc(c1)-c1c(C(C)C)n(C\C(F)=C\CN)c2ccc(C)nc12 InChI=1S/C23H28FN3O2S/c1-5-30(28,29)19-8-6-7-17(13-19)21-22-20(10-9-16(4)26-22)27(23(21)15(2)3)14-18(24)11-12-25/h6-11,13,15H,5,12,14,25H2,1-4H3/b18-11- JMDGXURWTPBBKZ-WQRHYEAKSA-N 454320 (Z)-4-(3-(3-(ethylsulfonyl)phenyl)-2- isopropyl-5-methyl-1H-pyrrolo[3,2- b]pyridin-1-yl)-3-fluorobut-2-en-1-amine::US10717733, Compound 113::US11098045, Compound 113 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454320&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340722 440970198 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081227 CCS(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(C)nc12 InChI=1S/C21H24FN3O2S/c1-4-28(26,27)18-7-5-6-16(12-18)20-15(3)25(13-17(22)10-11-23)19-9-8-14(2)24-21(19)20/h5-10,12H,4,11,13,23H2,1-3H3/b17-10- AYZZKAOGENBSFB-YVLHZVERSA-N 454321 (Z)-4-(3-(3-(ethylsulfonyl)phenyl)-2,5- dimethyl-1H-pyrrolo[3,2-b]pyridin-1-yl)- 3-fluorobut-2-en-1-amine::US10717733, Compound 114::US11098045, Compound 114 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454321 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454321&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302734 440970199 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081229 Cc1c(-c2cccc(c2)S(C)(=O)=O)c2nc(CF)ccc2n1C\C(F)=C\CN InChI=1S/C20H21F2N3O2S/c1-13-19(14-4-3-5-17(10-14)28(2,26)27)20-18(7-6-16(11-21)24-20)25(13)12-15(22)8-9-23/h3-8,10H,9,11-12,23H2,1-2H3/b15-8- JPBMGMVQTZIBNS-NVNXTCNLSA-N 454322 (Z)-3-fluoro-4-(5-(fluoromethyl)-2- methyl-3-(3-(methylsulfonyl)phenyl)-1H- pyrrolo[3,2-b]pyridin-1-yl)but-2-en-1- amine::US10717733, Compound 115::US11098045, Compound 115 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454322 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454322&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302771 440970200 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081231 Cc1c(-c2cccc(c2)S(C)(=O)=O)c2nc(ccc2n1C\C(F)=C\CN)C(C)(C)O InChI=1S/C22H26FN3O3S/c1-14-20(15-6-5-7-17(12-15)30(4,28)29)21-18(26(14)13-16(23)10-11-24)8-9-19(25-21)22(2,3)27/h5-10,12,27H,11,13,24H2,1-4H3/b16-10- GTDQVLPLHMHYBU-YBEGLDIGSA-N 454323 (Z)-2-(1-(4-amino-2-fluorobut-2-en-1-yl- 2-methyl-3-(3-(methylsulfonyl)phenyl)- 1H-pyrrolo[3,2-b]pyridin-5-yl)propan-2-ol::US10717733, Compound 116::US11098045, Compound 116 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454323 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454323&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130340699 440970201 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391 1081233 CC(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(nc12)C(C)(C)O InChI=1S/C24H30FN3O3S/c1-15(2)32(30,31)19-8-6-7-17(13-19)22-16(3)28(14-18(25)11-12-26)20-9-10-21(24(4,5)29)27-23(20)22/h6-11,13,15,29H,12,14,26H2,1-5H3/b18-11- RKQWCPPUHXDGML-WQRHYEAKSA-N 454324 (Z)-2-(1-(4-amino-2-fluorobut-2-en-1-yl)- 3-(3-(isopropylsulfonyl)phenyl)-2-methyl- 1H-pyrrolo[3,2-b]pyridin-5-yl)propan-2-ol::US10717733, Compound 117::US11098045, Compound 117 Oxidized low-density lipoprotein receptor 1 >300 US Patent 10.7270/Q2QC06PC aid1805856 US11098045 Findlay, AD; Turner, CI; Deodhar, M; Foot, JS; Jarolimek, W; Zhou, W; Robertson, AD Pharmaxis Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=894&target=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454324&enzyme=Oxidized+low-density+lipoprotein+receptor+1&column=ki&startPg=0&Increment=50&submit=Search 130302754 440970202 1 MTVDDPKGMKDQLDQKPNGKTAKGFVSSWRWYPAAVTLGVLCLGLLVTVILLILQLSQVSDLIKKQQANITHQEDILEGQILAQRRSEKSAQESQKELKEMIETLAHKLDEKSKKLMELHRQNLNLQEVLKEAANYSGPCPQDWLWHEENCYQFSSGSFNWEKSQENCLSLDAHLLKINSTDELEFIQQMIAHSSFPFWMGLSMRKPNYSWLWEDGTPLTPHLFRIQGAVSRMYPSGTCAYIQRGTVFAENCILTAFSICQKKANLLRAQ Oxidized low-density lipoprotein receptor 1 OLR1_BOVIN P79391